JP2018536433A5 - - Google Patents
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- Publication number
- JP2018536433A5 JP2018536433A5 JP2018541546A JP2018541546A JP2018536433A5 JP 2018536433 A5 JP2018536433 A5 JP 2018536433A5 JP 2018541546 A JP2018541546 A JP 2018541546A JP 2018541546 A JP2018541546 A JP 2018541546A JP 2018536433 A5 JP2018536433 A5 JP 2018536433A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- hbv
- nucleotide sequence
- antigenic fragment
- arenavirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021116562A JP2021182922A (ja) | 2015-11-04 | 2021-07-14 | B型肝炎ウイルスに対するワクチン |
| JP2023180121A JP7777907B2 (ja) | 2015-11-04 | 2023-10-19 | B型肝炎ウイルスに対するワクチン |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250639P | 2015-11-04 | 2015-11-04 | |
| US62/250,639 | 2015-11-04 | ||
| PCT/EP2016/076591 WO2017076988A1 (en) | 2015-11-04 | 2016-11-03 | Vaccines against hepatitis b virus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021116562A Division JP2021182922A (ja) | 2015-11-04 | 2021-07-14 | B型肝炎ウイルスに対するワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018536433A JP2018536433A (ja) | 2018-12-13 |
| JP2018536433A5 true JP2018536433A5 (enExample) | 2020-03-26 |
| JP6914950B2 JP6914950B2 (ja) | 2021-08-11 |
Family
ID=57249796
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541546A Active JP6914950B2 (ja) | 2015-11-04 | 2016-11-03 | B型肝炎ウイルスに対するワクチン |
| JP2021116562A Pending JP2021182922A (ja) | 2015-11-04 | 2021-07-14 | B型肝炎ウイルスに対するワクチン |
| JP2023180121A Active JP7777907B2 (ja) | 2015-11-04 | 2023-10-19 | B型肝炎ウイルスに対するワクチン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021116562A Pending JP2021182922A (ja) | 2015-11-04 | 2021-07-14 | B型肝炎ウイルスに対するワクチン |
| JP2023180121A Active JP7777907B2 (ja) | 2015-11-04 | 2023-10-19 | B型肝炎ウイルスに対するワクチン |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US11214598B2 (enExample) |
| EP (2) | EP3371316B1 (enExample) |
| JP (3) | JP6914950B2 (enExample) |
| KR (2) | KR102832178B1 (enExample) |
| CN (2) | CN108779472B (enExample) |
| AU (2) | AU2016348675B2 (enExample) |
| CA (1) | CA3003557A1 (enExample) |
| DK (1) | DK3371316T3 (enExample) |
| ES (1) | ES2934698T3 (enExample) |
| FI (1) | FI3371316T3 (enExample) |
| HR (1) | HRP20221474T1 (enExample) |
| HU (1) | HUE060648T2 (enExample) |
| IL (2) | IL259077B2 (enExample) |
| LT (1) | LT3371316T (enExample) |
| MX (2) | MX2018005569A (enExample) |
| PL (1) | PL3371316T3 (enExample) |
| PT (1) | PT3371316T (enExample) |
| SG (1) | SG11201803474UA (enExample) |
| SI (1) | SI3371316T1 (enExample) |
| WO (1) | WO2017076988A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2604695B1 (en) | 2007-12-27 | 2022-11-16 | Universität Zürich | Replication-defective arenavirus vectors |
| AU2014359276B2 (en) | 2013-12-03 | 2021-01-28 | Hookipa Biotech Gmbh | CMV vaccines |
| PL3218504T3 (pl) | 2014-11-13 | 2021-02-08 | Université De Genève | Trójsegmentowe arenawirusy jako wektory szczepionkowe |
| WO2016198531A2 (en) | 2015-06-10 | 2016-12-15 | Hookipa Biotech Ag | Hpv vaccines |
| CN108779472B (zh) * | 2015-11-04 | 2022-09-09 | 霍欧奇帕生物科技有限公司 | 针对乙型肝炎病毒的疫苗 |
| US11266727B2 (en) | 2015-11-12 | 2022-03-08 | Hookipa Biotech Gmbh | Arenavirus particles as cancer vaccines |
| FI3526323T3 (fi) | 2016-10-14 | 2023-06-06 | Prec Biosciences Inc | Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja |
| JP2022010188A (ja) * | 2017-02-03 | 2022-01-14 | 株式会社三洋物産 | 遊技機 |
| JP2022010187A (ja) * | 2017-02-03 | 2022-01-14 | 株式会社三洋物産 | 遊技機 |
| EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
| US11389531B2 (en) | 2017-12-19 | 2022-07-19 | Janssen Sciences Ireland Unlimited Company | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| EA202091516A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv) |
| US10870691B2 (en) | 2018-04-05 | 2020-12-22 | Gilead Sciences, Inc. | Antibodies and fragments thereof that bind hepatitis B virus protein X |
| US11142750B2 (en) | 2018-04-12 | 2021-10-12 | Precision Biosciences, Inc. | Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome |
| MA56524A (fr) | 2019-06-18 | 2022-04-27 | Janssen Sciences Ireland Unlimited Co | Vecteurs d'arénavirus pour vaccins contre le virus de l'hépatite b (vhb) et utilisations associées |
| KR20220041080A (ko) * | 2019-06-18 | 2022-03-31 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | B형 간염 바이러스(hbv) 백신 및 항-pd-1 또는 항-pc-l1 항체의 조합 |
| BR112021026376A2 (pt) | 2019-06-25 | 2022-05-10 | Gilead Sciences Inc | Proteínas de fusão flt3l-fc e métodos de uso |
| JP7398556B2 (ja) | 2019-09-30 | 2023-12-14 | ギリアード サイエンシーズ, インコーポレイテッド | Hbvワクチン及びhbvを治療する方法 |
| CN114981443A (zh) * | 2019-11-07 | 2022-08-30 | 巴塞尔大学 | 作为载体的沙粒病毒 |
| WO2021113765A1 (en) | 2019-12-06 | 2021-06-10 | Precision Biosciences, Inc. | Optimized engineered meganucleases having specificity for a recognition sequence in the hepatitis b virus genome |
| US11845723B2 (en) | 2019-12-24 | 2023-12-19 | Gilead Sciences, Inc. | Diacylglycerol kinase modulating compounds |
| WO2021188959A1 (en) | 2020-03-20 | 2021-09-23 | Gilead Sciences, Inc. | Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same |
| KR102375703B1 (ko) | 2020-07-28 | 2022-03-17 | 경북대학교 산학협력단 | 사물 인터넷 환경에서 CoAP 기반의 데이터 스트리밍 방법 및 통신 시스템 |
| WO2022200373A2 (en) | 2021-03-23 | 2022-09-29 | Hookipa Biotech Gmbh | Arenaviruses used in treatments of prostate cancer |
| WO2022226242A1 (en) * | 2021-04-21 | 2022-10-27 | La Jolla Institute For Immunology | Engineered arenavirus glycoprotein compositions, methods and use thereof |
| CN113201051B (zh) * | 2021-04-27 | 2022-08-02 | 复旦大学 | 一种乙肝病毒表面蛋白突变体及其在抗乙肝病毒中的应用 |
| WO2022241134A1 (en) | 2021-05-13 | 2022-11-17 | Gilead Sciences, Inc. | COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS |
| CN117377671A (zh) | 2021-06-23 | 2024-01-09 | 吉利德科学公司 | 二酰基甘油激酶调节化合物 |
| AU2022297367B2 (en) | 2021-06-23 | 2025-04-10 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| IL309378A (en) | 2021-06-23 | 2024-02-01 | Gilead Sciences Inc | Diacylglyercol kinase modulating compounds |
| CA3222277A1 (en) | 2021-06-23 | 2022-12-29 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| WO2025056782A1 (en) | 2023-09-15 | 2025-03-20 | Hookipa Biotech Gmbh | Arenavirus formulations, methods and uses thereof |
| WO2025240246A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies with ribavirin |
| WO2025240242A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies with ribavirin |
| US20250345389A1 (en) | 2024-05-13 | 2025-11-13 | Gilead Sciences, Inc. | Combination therapies |
| WO2025240244A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies comprising bulevirtide and lonafarnib for use in the treatment of hepatitis d virus infection |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4722840A (en) * | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| JPH1084967A (ja) | 1996-09-19 | 1998-04-07 | Fujirebio Inc | B型肝炎のe抗原 |
| BR9915942A (pt) * | 1998-12-04 | 2001-08-21 | Biogen Inc | Patìculas de antìgeno de núcleo de hbv com componentes imunogênicos múltiplos ligados através de ligantes de peptìdeo |
| FR2803599B1 (fr) * | 2000-01-06 | 2004-11-19 | Inst Nat Sante Rech Med | Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications |
| US20100183652A1 (en) * | 2002-02-21 | 2010-07-22 | Mark Page | STABILIZED HBc CHIMER PARTICLES AS THERAPEUTIC VACCINE FOR CHRONIC HEPATITIS |
| WO2006125983A1 (en) * | 2005-05-23 | 2006-11-30 | Oxxon Therapeutics Ltd | Compositions for inducing an immune response against hepatitis b |
| CN101037476A (zh) * | 2006-03-15 | 2007-09-19 | 复旦大学 | 一种用于制备抗体化乙肝疫苗的融合蛋白及其载体 |
| CA2646891A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Immunopotentiating compounds |
| ES2376492T3 (es) | 2006-03-23 | 2012-03-14 | Novartis Ag | Compuestos de imidazoquinoxalina como inmunomoduladores. |
| NZ594510A (en) * | 2006-12-27 | 2012-06-29 | Harvard College | Compositions and methods for the treatment of infections and tumors |
| EP2604695B1 (en) | 2007-12-27 | 2022-11-16 | Universität Zürich | Replication-defective arenavirus vectors |
| US10076570B2 (en) * | 2009-08-07 | 2018-09-18 | Transgene S.A. | Composition for treating HBV infection |
| US9393299B2 (en) | 2009-08-07 | 2016-07-19 | Transgene S.A. | Composition for treating HBV infection |
| PH12013501683A1 (en) * | 2011-02-12 | 2019-07-17 | Globeimmune Inc | Yeast-based therapeutic for chronic hepatitis b infection |
| WO2012162428A1 (en) | 2011-05-23 | 2012-11-29 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prime-boost vaccination for viral infection |
| KR102195196B1 (ko) | 2012-01-24 | 2020-12-28 | 샌포드 헬스 | 종양원성 바이러스성 폴리펩티드 양성 종양 치료용 폴리뉴클레오티드 |
| US9809801B2 (en) | 2013-03-15 | 2017-11-07 | Université De Genève | Anti-mycobacterial vaccines |
| GB201305361D0 (en) | 2013-03-25 | 2013-05-08 | Univ Edinburgh | Enhanced expression |
| AU2014359276B2 (en) | 2013-12-03 | 2021-01-28 | Hookipa Biotech Gmbh | CMV vaccines |
| US10342861B2 (en) | 2014-05-27 | 2019-07-09 | University Of Rochester | Arenavirus vaccine |
| US9943585B2 (en) | 2014-07-30 | 2018-04-17 | University Of Rochester | Methods and compositions related to reorganization of arenavirus genome for development of novel arenavirus live-attenuated vaccines (LAV) |
| US10533159B2 (en) | 2014-09-22 | 2020-01-14 | Regents Of The University Of Minnesota | Pichinde virus reverse genetics systems and methods of use |
| GB201419572D0 (en) | 2014-11-03 | 2014-12-17 | Pirbright Inst The | Virus |
| PL3218504T3 (pl) * | 2014-11-13 | 2021-02-08 | Université De Genève | Trójsegmentowe arenawirusy jako wektory szczepionkowe |
| DE102015207036A1 (de) | 2015-04-17 | 2016-10-20 | Karl Sebastian Lang | Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften |
| WO2016198531A2 (en) | 2015-06-10 | 2016-12-15 | Hookipa Biotech Ag | Hpv vaccines |
| WO2017068190A1 (en) | 2015-10-23 | 2017-04-27 | Institut Pasteur | Recombinant mopeia virus and vaccine platform |
| CN108779472B (zh) | 2015-11-04 | 2022-09-09 | 霍欧奇帕生物科技有限公司 | 针对乙型肝炎病毒的疫苗 |
| US11266727B2 (en) | 2015-11-12 | 2022-03-08 | Hookipa Biotech Gmbh | Arenavirus particles as cancer vaccines |
| US10980877B2 (en) | 2016-04-28 | 2021-04-20 | The University Of Chicago | Method for treating melanoma using lymphangiogenesis inducers and a melanoma-specific antigen |
| MX2018013956A (es) | 2016-05-18 | 2019-07-04 | Hookipa Biotech Gmbh | Virus pichinde de tres segmentos como vectores de vacunas. |
| US20200206334A1 (en) | 2016-11-04 | 2020-07-02 | Hookipa Biotech Gmbh | Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
| US20200113995A1 (en) | 2017-04-07 | 2020-04-16 | Hookipa Biotech Gmbh | Arenavirus particles to treat solid tumors |
-
2016
- 2016-11-03 CN CN201680077751.0A patent/CN108779472B/zh active Active
- 2016-11-03 SG SG11201803474UA patent/SG11201803474UA/en unknown
- 2016-11-03 CN CN202211051785.6A patent/CN115948467A/zh active Pending
- 2016-11-03 PT PT167915735T patent/PT3371316T/pt unknown
- 2016-11-03 EP EP16791573.5A patent/EP3371316B1/en active Active
- 2016-11-03 DK DK16791573.5T patent/DK3371316T3/da active
- 2016-11-03 KR KR1020187015548A patent/KR102832178B1/ko active Active
- 2016-11-03 SI SI201631654T patent/SI3371316T1/sl unknown
- 2016-11-03 IL IL259077A patent/IL259077B2/en unknown
- 2016-11-03 US US15/773,512 patent/US11214598B2/en active Active
- 2016-11-03 MX MX2018005569A patent/MX2018005569A/es unknown
- 2016-11-03 KR KR1020257022585A patent/KR20250107977A/ko active Pending
- 2016-11-03 PL PL16791573.5T patent/PL3371316T3/pl unknown
- 2016-11-03 IL IL314371A patent/IL314371A/en unknown
- 2016-11-03 WO PCT/EP2016/076591 patent/WO2017076988A1/en not_active Ceased
- 2016-11-03 ES ES16791573T patent/ES2934698T3/es active Active
- 2016-11-03 FI FIEP16791573.5T patent/FI3371316T3/fi active
- 2016-11-03 AU AU2016348675A patent/AU2016348675B2/en active Active
- 2016-11-03 EP EP22201924.2A patent/EP4177348A1/en active Pending
- 2016-11-03 JP JP2018541546A patent/JP6914950B2/ja active Active
- 2016-11-03 LT LTEPPCT/EP2016/076591T patent/LT3371316T/lt unknown
- 2016-11-03 HR HRP20221474TT patent/HRP20221474T1/hr unknown
- 2016-11-03 CA CA3003557A patent/CA3003557A1/en active Pending
- 2016-11-03 HU HUE16791573A patent/HUE060648T2/hu unknown
-
2018
- 2018-05-03 MX MX2023013140A patent/MX2023013140A/es unknown
-
2021
- 2021-07-14 JP JP2021116562A patent/JP2021182922A/ja active Pending
- 2021-11-24 US US17/535,121 patent/US20220073568A1/en not_active Abandoned
-
2023
- 2023-01-10 AU AU2023200108A patent/AU2023200108B2/en active Active
- 2023-10-19 JP JP2023180121A patent/JP7777907B2/ja active Active
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