JP6898060B2 - Ｄｎａ抗体構築物およびその使用方法 - Google Patents

Ｄｎａ抗体構築物およびその使用方法 Download PDF

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JP6898060B2
JP6898060B2 JP2015548014A JP2015548014A JP6898060B2 JP 6898060 B2 JP6898060 B2 JP 6898060B2 JP 2015548014 A JP2015548014 A JP 2015548014A JP 2015548014 A JP2015548014 A JP 2015548014A JP 6898060 B2 JP6898060 B2 JP 6898060B2
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nucleic acid
acid sequence
seq
antigen
env
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JP2016501535A5 (enExample
JP2016501535A (ja
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ビー．ウェイナー デイビッド
ビー．ウェイナー デイビッド
マトゥマニ カルピア
マトゥマニ カルピア
サーデサイ ニランジャン
サーデサイ ニランジャン
フリンガイ セリーク
フリンガイ セリーク
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
イノビオ ファーマシューティカルズ，インコーポレイティド
イノビオ ファーマシューティカルズ，インコーポレイティド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
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    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
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    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
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    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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JP2015548014A 2012-12-13 2013-12-13 Ｄｎａ抗体構築物およびその使用方法 Expired - Fee Related JP6898060B2 (ja)

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US201261737094P 2012-12-13 2012-12-13
US61/737,094 2012-12-13
US201361881376P 2013-09-23 2013-09-23
US61/881,376 2013-09-23
US201361896646P 2013-10-28 2013-10-28
US61/896,646 2013-10-28
PCT/US2013/075137 WO2014093894A2 (en) 2012-12-13 2013-12-13 Dna antibody constructs and method of using same

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JP2019061531A Division JP2019115355A (ja) 2012-12-13 2019-03-27 Ｄｎａ抗体構築物およびその使用方法
JP2021016537A Division JP2021087433A (ja) 2012-12-13 2021-02-04 Ｄｎａ抗体構築物およびその使用方法

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JP2016501535A JP2016501535A (ja) 2016-01-21
JP2016501535A5 JP2016501535A5 (enExample) 2017-02-02
JP6898060B2 true JP6898060B2 (ja) 2021-07-07

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JP2015548014A Expired - Fee Related JP6898060B2 (ja) 2012-12-13 2013-12-13 Ｄｎａ抗体構築物およびその使用方法
JP2019061531A Pending JP2019115355A (ja) 2012-12-13 2019-03-27 Ｄｎａ抗体構築物およびその使用方法
JP2020035240A Pending JP2020108381A (ja) 2012-12-13 2020-03-02 Ｄｎａ抗体構築物及びその使用方法
JP2021016537A Withdrawn JP2021087433A (ja) 2012-12-13 2021-02-04 Ｄｎａ抗体構築物およびその使用方法
JP2023040876A Pending JP2023080085A (ja) 2012-12-13 2023-03-15 Ｄｎａ抗体構築物およびその使用方法
JP2023108341A Pending JP2023138998A (ja) 2012-12-13 2023-06-30 Ｄｎａ抗体構築物及びその使用方法

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JP2020035240A Pending JP2020108381A (ja) 2012-12-13 2020-03-02 Ｄｎａ抗体構築物及びその使用方法
JP2021016537A Withdrawn JP2021087433A (ja) 2012-12-13 2021-02-04 Ｄｎａ抗体構築物およびその使用方法
JP2023040876A Pending JP2023080085A (ja) 2012-12-13 2023-03-15 Ｄｎａ抗体構築物およびその使用方法
JP2023108341A Pending JP2023138998A (ja) 2012-12-13 2023-06-30 Ｄｎａ抗体構築物及びその使用方法

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US (4) US9994629B2 (enExample)
EP (1) EP2931318A4 (enExample)
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KR (4) KR20210088741A (enExample)
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AU (7) AU2013358944B2 (enExample)
BR (2) BR112015013700A8 (enExample)
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EP2931318A4 (en) 2012-12-13 2016-07-20 Univ Pennsylvania DNA ANTIBODY CONSTRUCTS AND METHODS FOR USE THEREOF
SG11201604719WA (en) * 2013-12-13 2016-07-28 Univ Pennsylvania Dna antibody constructs and method of using same
KR102586707B1 (ko) * 2014-10-01 2023-10-11 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 항원 및 어쥬번트로서 인터류킨-21을 갖는 백신
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