|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US6218525B1
(en)
|
1988-02-25 |
2001-04-17 |
The General Hospital Corporation |
Nucleic acid encoding CD28
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
|
US6534055B1
(en)
|
1988-11-23 |
2003-03-18 |
Genetics Institute, Inc. |
Methods for selectively stimulating proliferation of T cells
|
|
US6685941B1
(en)
|
1988-11-23 |
2004-02-03 |
The Regents Of The University Of Michigan |
Methods of treating autoimmune disease via CTLA-4Ig
|
|
US6291159B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
|
US6641809B1
(en)
|
1990-03-26 |
2003-11-04 |
Bristol-Myers Squibb Company |
Method of regulating cellular processes mediated by B7 and CD28
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US7063943B1
(en)
|
1990-07-10 |
2006-06-20 |
Cambridge Antibody Technology |
Methods for producing members of specific binding pairs
|
|
WO1992009690A2
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
|
US5871907A
(en)
|
1991-05-15 |
1999-02-16 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
CA2103059C
(en)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Method for making humanized antibodies
|
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
US5844095A
(en)
|
1991-06-27 |
1998-12-01 |
Bristol-Myers Squibb Company |
CTLA4 Ig fusion proteins
|
|
US6887471B1
(en)
|
1991-06-27 |
2005-05-03 |
Bristol-Myers Squibb Company |
Method to inhibit T cell interactions with soluble B7
|
|
ES2123001T5
(es)
|
1991-06-27 |
2009-04-16 |
Bristol-Myers Squibb Company |
Receptor ctl4a, proteinas de fusion que lo contienen y sus usos.
|
|
US5851795A
(en)
|
1991-06-27 |
1998-12-22 |
Bristol-Myers Squibb Company |
Soluble CTLA4 molecules and uses thereof
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5773253A
(en)
|
1993-01-22 |
1998-06-30 |
Bristol-Myers Squibb Company |
MYPPPY variants of CTL A4 and uses thereof
|
|
US6482919B2
(en)
|
1993-02-01 |
2002-11-19 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
|
US5942607A
(en)
|
1993-07-26 |
1999-08-24 |
Dana-Farber Cancer Institute |
B7-2: a CTLA4/CD28 ligand
|
|
US6130316A
(en)
|
1993-07-26 |
2000-10-10 |
Dana Farber Cancer Institute |
Fusion proteins of novel CTLA4/CD28 ligands and uses therefore
|
|
US6084067A
(en)
|
1993-07-26 |
2000-07-04 |
Dana-Farber Cancer Institute |
CTLA4/CD28 ligands and uses therefor
|
|
US6218510B1
(en)
|
1994-03-02 |
2001-04-17 |
Brigham & Woman's Hospital |
B7-1 and B7-2 polypeptides
|
|
US6713279B1
(en)
|
1995-12-07 |
2004-03-30 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines and enzymes
|
|
US6750334B1
(en)
|
1996-02-02 |
2004-06-15 |
Repligen Corporation |
CTLA4-immunoglobulin fusion proteins having modified effector functions and uses therefor
|
|
AU737910B2
(en)
|
1997-01-31 |
2001-09-06 |
Regents Of The University Of California, The |
Chimeric antibody fusion proteins for the recruitment and stimulation of an antitumor immune response
|
|
US6294170B1
(en)
|
1997-08-08 |
2001-09-25 |
Amgen Inc. |
Composition and method for treating inflammatory diseases
|
|
US6730512B2
(en)
|
1997-04-09 |
2004-05-04 |
Amdl, Inc. |
Combination immunogene therapy
|
|
DE69827507T2
(de)
|
1997-06-11 |
2006-03-09 |
Borean Pharma A/S |
Trimerisierendes modul
|
|
US6165476A
(en)
|
1997-07-10 |
2000-12-26 |
Beth Israel Deaconess Medical Center |
Fusion proteins with an immunoglobulin hinge region linker
|
|
US5891432A
(en)
|
1997-07-29 |
1999-04-06 |
The Immune Response Corporation |
Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
DK1068241T3
(da)
|
1998-04-02 |
2008-02-04 |
Genentech Inc |
Antistofvarianter og fragmenter deraf
|
|
GB9823071D0
(en)
|
1998-10-21 |
1998-12-16 |
Affibody Technology Ab |
A method
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
ES2694002T3
(es)
|
1999-01-15 |
2018-12-17 |
Genentech, Inc. |
Polipéptido que comprende una región Fc de IgG1 humana variante
|
|
US8624010B1
(en)
|
1999-02-03 |
2014-01-07 |
Steven K. Yoshinaga |
Nucleic acids encoding B7RP1
|
|
US7446189B1
(en)
|
1999-04-30 |
2008-11-04 |
Institut De Recherches Cliniques De Montreal |
Nucleic acids encoding mutant human CD80 and compositions comprising the same
|
|
GB9917027D0
(en)
|
1999-07-20 |
1999-09-22 |
Affibody Technology Sweeden Ab |
In vitro selection and optional identification of polypeptides using solid support carriers
|
|
WO2001021796A2
(en)
|
1999-09-21 |
2001-03-29 |
Genetics Institute, Inc. |
Gl50 molecules and uses therefor
|
|
CA2395945C
(en)
|
2000-01-03 |
2013-12-24 |
Tr Associates, L.L.C. |
Novel chimeric proteins and methods for using the same
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
US7094874B2
(en)
|
2000-05-26 |
2006-08-22 |
Bristol-Myers Squibb Co. |
Soluble CTLA4 mutant molecules
|
|
UA87432C2
(uk)
|
2000-05-26 |
2009-07-27 |
Бристол-Майерс Сквибб Компани |
Розчинний мутантний ctla4 та його застосування
|
|
US7183376B2
(en)
|
2000-06-23 |
2007-02-27 |
Maxygen, Inc. |
Variant B7 co-stimulatory molecules
|
|
AU2001272978A1
(en)
|
2000-06-23 |
2002-01-08 |
Maxygen, Inc. |
Novel co-stimulatory molecules
|
|
US20020164600A1
(en)
|
2000-06-28 |
2002-11-07 |
Gordon Freeman |
PD-L2 molecules: novel PD-1 ligands and uses therefor
|
|
US20040022787A1
(en)
|
2000-07-03 |
2004-02-05 |
Robert Cohen |
Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
|
|
PL212205B1
(pl)
|
2000-07-03 |
2012-08-31 |
Bristol Myers Squibb Co |
Zastosowanie rozpuszczalnej zmutowanej cząsteczki CTLA4
|
|
US6635750B1
(en)
|
2000-07-20 |
2003-10-21 |
Millennium Pharmaceuticals, Inc. |
B7-H2 nucleic acids, members of the B7 family
|
|
PL204899B1
(pl)
|
2001-05-23 |
2010-02-26 |
Bristol Myers Squibb Co |
Zastosowanie rozpuszczalnej zmutowanej cząsteczki CTLA4
|
|
EP1497426A2
(en)
|
2001-06-22 |
2005-01-19 |
Maxygen, Inc. |
Co-stimulatory molecules
|
|
MXPA04000034A
(es)
|
2001-06-29 |
2005-11-23 |
Univ Leland Stanford Junior |
Genes regulatorios de celulas t metodos para utilizar los mismos.
|
|
KR100453877B1
(ko)
|
2001-07-26 |
2004-10-20 |
메덱스젠 주식회사 |
연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
|
|
CA2466279A1
(en)
|
2001-11-13 |
2003-05-22 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
|
US7235631B2
(en)
|
2002-02-07 |
2007-06-26 |
Mayo Foundation For Medical Education And Research |
ICOS mutants
|
|
US7223408B2
(en)
*
|
2002-10-03 |
2007-05-29 |
Wyeth Holdings Corporation |
Human papillomavirus polypeptides and immunogenic compositions
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
AR042485A1
(es)
|
2002-12-16 |
2005-06-22 |
Genentech Inc |
Anticuerpo humanizado que se une al cd20 humano
|
|
SI1576182T2
(sl)
|
2002-12-23 |
2020-07-31 |
Bristol-Myers Squibb Company |
Izboljšava kvalitete izdelka v procesih pridelave beljakovin v celični kulturi sesalcev
|
|
WO2004072286A1
(ja)
|
2003-01-23 |
2004-08-26 |
Ono Pharmaceutical Co., Ltd. |
ヒトｐｄ−１に対し特異性を有する物質
|
|
CA2762015A1
(en)
|
2003-08-04 |
2005-02-24 |
Bristol-Myers Squibb Company |
Methods for treating cardiovascular disease using a soluble ctla4 molecule
|
|
NZ548255A
(en)
|
2004-02-02 |
2010-10-29 |
Ambrx Inc |
Modified human interferon polypeptides and their uses
|
|
CA2885854C
(en)
|
2004-04-13 |
2017-02-21 |
F. Hoffmann-La Roche Ag |
Anti-p-selectin antibodies
|
|
DK2471813T3
(en)
|
2004-07-15 |
2015-03-02 |
Xencor Inc |
Optimized Fc variants
|
|
EP1771573A4
(en)
|
2004-07-21 |
2009-02-18 |
Ambrx Inc |
BIOSYNTHETIC POLYPEPTIDES OBTAINED FROM NON-NATURALLY CITED AMINO ACIDS
|
|
TWI309240B
(en)
|
2004-09-17 |
2009-05-01 |
Hoffmann La Roche |
Anti-ox40l antibodies
|
|
JP2008520214A
(ja)
|
2004-11-22 |
2008-06-19 |
ボレアン・ファルマ・アンパルトセルスカブ |
Ｔｎｆアンタゴニスト
|
|
CN104803865A
(zh)
|
2004-12-22 |
2015-07-29 |
Ambrx公司 |
含有非天然氨基酸和多肽的组合物、涉及非天然氨基酸和多肽的方法以及其用途
|
|
EA013122B1
(ru)
|
2005-04-06 |
2010-02-26 |
Бристол-Маерс Сквибб Компани |
Способы лечения иммунных нарушений, связанных с пересадкой трансплантата, растворимым мутантным ctla4
|
|
CA2625540C
(en)
|
2005-11-08 |
2017-03-21 |
Ambrx, Inc. |
Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
|
|
JP5096369B2
(ja)
|
2005-12-20 |
2012-12-12 |
ブリストル−マイヤーズ スクイブ カンパニー |
組成物および組成物の製造方法
|
|
CN106008699A
(zh)
|
2006-09-08 |
2016-10-12 |
Ambrx公司 |
经修饰的人类血浆多肽或Fc骨架和其用途
|
|
GB0620934D0
(en)
|
2006-10-20 |
2006-11-29 |
Cambridge Antibody Tech |
Protein variants
|
|
EP2102241A2
(en)
|
2006-12-15 |
2009-09-23 |
Ablynx N.V. |
Amino acid sequences that modulate the interaction between cells of the immune system
|
|
DK2856876T3
(en)
|
2007-03-30 |
2018-04-03 |
Memorial Sloan Kettering Cancer Center |
Constitutive expression of co-stimulatory ligands on adoptively transmitted T lymphocytes
|
|
CN101675071B
(zh)
|
2007-05-02 |
2014-06-18 |
Ambrx公司 |
经修饰干扰素β多肽和其用途
|
|
JP2010533649A
(ja)
|
2007-07-13 |
2010-10-28 |
ザ ジョンズ ホプキンス ユニバーシティー |
Ｂ７−ｄｃ改変体
|
|
RU2506275C2
(ru)
|
2007-11-01 |
2014-02-10 |
Астеллас Фарма Инк. |
Иммуносупрессорные полипептиды и нуклеиновые кислоты
|
|
CA2713872A1
(en)
|
2008-02-21 |
2009-08-27 |
Burnham Institute For Medical Research |
Methods and compositions related to peptides and proteins with c-terminal elements
|
|
US20110015345A1
(en)
|
2008-03-19 |
2011-01-20 |
Ambrx, Inc. |
Modified FGF-23 Polypeptides and Their Uses
|
|
JP5770624B2
(ja)
|
2008-04-09 |
2015-08-26 |
ジェネンテック， インコーポレイテッド |
免疫関連疾患の治療のための新規組成物と方法
|
|
US7915222B2
(en)
|
2008-05-05 |
2011-03-29 |
Bristol-Myers Squibb Company |
Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis
|
|
EP2285980B1
(en)
|
2008-06-02 |
2017-05-17 |
Institut Gustave Roussy |
NATURAL KILLER p30 (NKp30) DYSFUNCTION AND THE BIOLOGICAL APPLICATIONS THEREOF
|
|
US9931386B2
(en)
|
2008-06-16 |
2018-04-03 |
Atsuo Ochi |
Recombinant multiple domain fusion protein mitogens and use thereof for inducing enhancement or repression of antigen-specific immunity
|
|
CN106928339A
(zh)
|
2008-07-23 |
2017-07-07 |
Ambrx 公司 |
经修饰的牛g‑csf多肽和其用途
|
|
MX2011002250A
(es)
|
2008-08-25 |
2011-08-17 |
Amplimmune Inc |
Antagonistas de muerte celular programada-1 y métodos de uso de los mismos.
|
|
RS54233B1
(sr)
|
2008-08-25 |
2015-12-31 |
Amplimmune Inc. |
Kompozicije pd-1 antagonista i postupci za njihovu primenu
|
|
CA2737026C
(en)
|
2008-09-26 |
2019-12-24 |
Ambrx, Inc. |
Modified animal erythropoietin polypeptides and their uses
|
|
CA2751489A1
(en)
|
2009-02-04 |
2010-08-12 |
Board Of Regents, The University Of Texas System |
Dual targeting of mir-208 and mir-499 in the treatment of cardiac disorders
|
|
CA2769822C
(en)
*
|
2009-08-13 |
2019-02-19 |
The Johns Hopkins University |
Methods of modulating immune function
|
|
CN104826106B
(zh)
|
2009-09-30 |
2019-01-11 |
斯隆凯特林防癌纪念中心 |
用于治疗癌症的组合免疫疗法
|
|
US9540426B2
(en)
|
2009-10-06 |
2017-01-10 |
Bristol-Myers Squibb Company |
Mammalian cell culture processes for protein production
|
|
JP2013512251A
(ja)
|
2009-11-24 |
2013-04-11 |
アンプリミューン、インコーポレーテッド |
Ｐｄ−ｌ１／ｐｄ−ｌ２の同時阻害
|
|
ES2724451T3
(es)
|
2010-02-04 |
2019-09-11 |
Univ Pennsylvania |
ICOS regula fundamentalmente la expansión y la función de linfocitos Th17 humanos inflamatorios
|
|
LT3053932T
(lt)
|
2010-02-19 |
2020-11-10 |
Xencor, Inc. |
Nauji ctla4-ig imunoadhezinai
|
|
PL2542590T5
(pl)
|
2010-03-05 |
2020-08-10 |
The Johns Hopkins University |
Kompozycje i sposoby dla ukierunkowanych immunomodulatorowych przeciwciał i białek fuzyjnych
|
|
US8642557B2
(en)
|
2010-03-12 |
2014-02-04 |
Abbvie Biotherapeutics Inc. |
CTLA4 proteins and their uses
|
|
CN107090029B
(zh)
*
|
2010-11-11 |
2021-07-13 |
港大科桥有限公司 |
可溶性 pd-1变体、融合构建体及其用途
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
US9469676B2
(en)
|
2011-04-13 |
2016-10-18 |
Bristol-Myers Squibb Company |
Fc fusion proteins comprising novel linkers or arrangements
|
|
US9409987B2
(en)
|
2011-04-15 |
2016-08-09 |
Compugen Ltd |
Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
|
|
TWI496886B
(zh)
|
2011-06-24 |
2015-08-21 |
Taipei Veteran General Hospital |
提升感染性與惡性疾病之治療之免疫反應
|
|
EP3357511B1
(en)
|
2011-06-30 |
2020-05-13 |
Genzyme Corporation |
Inhibitors of t-cell activation
|
|
US8956619B2
(en)
|
2011-10-25 |
2015-02-17 |
University Of Maryland, Baltimore County |
Soluble CD80 as a therapeutic to reverse immune supression in cancer patients
|
|
LT2785375T
(lt)
|
2011-11-28 |
2020-11-10 |
Merck Patent Gmbh |
Anti-pd-l1 antikūnai ir jų panaudojimas
|
|
CA3179537A1
(en)
|
2012-02-27 |
2013-09-06 |
Amunix Pharmaceuticals, Inc. |
Xten conjugate compositions and methods of making same
|
|
US9758566B2
(en)
|
2012-03-29 |
2017-09-12 |
The General Hospital Corporation |
Recombinant cytotoxic T-lymphocyte-associated protein 4 (CTLA4)
|
|
JP6228971B2
(ja)
|
2012-05-11 |
2017-11-08 |
メディミューン，エルエルシー |
Ｃｔｌａ−４バリアント
|
|
KR20150018604A
(ko)
|
2012-06-06 |
2015-02-23 |
온코메드 파마슈티칼스, 인크. |
히포 경로를 조절하는 결합제 및 그의 용도
|
|
KR20150033703A
(ko)
|
2012-06-27 |
2015-04-01 |
오르반 바이오테크 엘엘씨 |
당뇨병 치료를 위한 ctla4 융합 단백질
|
|
JP5857896B2
(ja)
|
2012-07-06 |
2016-02-10 |
東京エレクトロン株式会社 |
成膜装置の運転方法及び成膜装置
|
|
CA2892831A1
(en)
|
2012-12-04 |
2014-06-12 |
Oncomed Pharmaceuticals, Inc. |
Immunotherapy with binding agents
|
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
US9944689B2
(en)
|
2013-03-07 |
2018-04-17 |
The General Hospital Corporation |
Human CTLA4 mutants and use thereof
|
|
WO2014207748A1
(en)
|
2013-06-27 |
2014-12-31 |
Alexander Biro |
Soluble ctla-4 molecules and derivatives thereof for treatment of minimal change disease
|
|
GB201311475D0
(en)
|
2013-06-27 |
2013-08-14 |
Alligator Bioscience Ab |
Polypeptides
|
|
SG11201600310QA
(en)
|
2013-07-16 |
2016-02-26 |
Genentech Inc |
Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors
|
|
EP3101035B1
(en)
|
2014-01-28 |
2021-10-06 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Bifunctional fusion protein, preparation method therefor, and use thereof
|
|
ES2792849T3
(es)
|
2014-02-10 |
2020-11-12 |
Univ Emory |
Expresión de polipéptido químico con receptores de linfocitos variables en células inmunes y usos para tratar el cáncer
|
|
AU2015249656A1
(en)
|
2014-04-25 |
2016-11-03 |
Bristol-Myers Squibb Company |
Use of CTLA4 compound for achieving drug-free remission in subjects with early RA
|
|
ES2909957T3
(es)
|
2014-07-16 |
2022-05-11 |
Transgene |
Virus oncolítico para la expresión de moduladores de puntos de control inmunitarios
|
|
SG10201811841UA
(en)
|
2014-07-16 |
2019-02-27 |
Genentech Inc |
Methods of treating cancer using tigit inhibitors and anti-cancer agents
|
|
HRP20201153T1
(hr)
|
2014-08-08 |
2021-01-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Pd-1 sredstva visokog afiniteta i načini uporabe
|
|
SG11201701506PA
(en)
|
2014-09-03 |
2017-03-30 |
Bavarian Nordic As |
Recombinant modified vaccinia virus ankara (mva) filovirus vaccine
|
|
US20160145344A1
(en)
|
2014-10-20 |
2016-05-26 |
University Of Southern California |
Murine and human innate lymphoid cells and lung inflammation
|
|
CN107207597A
(zh)
|
2014-11-06 |
2017-09-26 |
儿研所儿童医学中心 |
用于癌症和自身免疫疾病的免疫疗法
|
|
WO2016118577A1
(en)
|
2015-01-22 |
2016-07-28 |
Medimmune, Llc |
Thymosin-beta-four fusion proteins
|
|
CN107708725A
(zh)
|
2015-04-02 |
2018-02-16 |
坎库雷有限公司 |
用于引发免疫应答的剂和组合物
|
|
WO2016164428A1
(en)
|
2015-04-06 |
2016-10-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Receptor-based antagonists of the programmed cell death 1 (pd-1) pathway
|
|
PT3283508T
(pt)
|
2015-04-17 |
2021-06-21 |
Alpine Immune Sciences Inc |
Proteínas imuno modulatórias com afinidades afináveis
|
|
TWI715587B
(zh)
|
2015-05-28 |
2021-01-11 |
美商安可美德藥物股份有限公司 |
Ｔｉｇｉｔ結合劑和彼之用途
|
|
UY36687A
(es)
|
2015-05-29 |
2016-11-30 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Anticuerpos contra ox40 y sus usos
|
|
SI3328419T1
(sl)
|
2015-07-30 |
2021-11-30 |
Macrogenics, Inc. |
PD-1-vezavne molekule in postopki uporabe le-teh
|
|
CA2993478A1
(en)
|
2015-07-31 |
2017-02-09 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immunomodulation
|
|
EP3328377A4
(en)
|
2015-07-31 |
2019-03-13 |
Tarveda Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR IMMUNE ONCOLOGY THERAPIES
|
|
CN114767833A
(zh)
|
2015-08-20 |
2022-07-22 |
弗劳恩霍夫应用研究促进协会 |
B7-h1融合多肽或多核苷酸用于治疗或预防肝衰竭的用途
|
|
MX2018003144A
(es)
|
2015-09-14 |
2018-09-11 |
Alpine Immune Sciences Inc |
Dominios de superfamilia de inmunoglobulina de variante ajustable y terapia con células genéticamente modificadas.
|
|
MY190324A
(en)
|
2015-10-02 |
2022-04-14 |
Symphogen As |
Anti-pd-1 antibodies and compositions
|
|
KR20180069903A
(ko)
|
2015-11-02 |
2018-06-25 |
파이브 프라임 테라퓨틱스, 인크. |
Cd80 세포외 도메인 폴리펩타이드 및 이들의 암 치료에서의 용도
|
|
TWI705972B
(zh)
|
2015-11-04 |
2020-10-01 |
臺北榮民總醫院 |
惡性病變的組合治療
|
|
AU2016370376B2
(en)
|
2015-12-14 |
2023-12-14 |
Macrogenics, Inc. |
Bispecific molecules having immunoreactivity with PD-1 and CTLA-4, and methods of use thereof
|
|
WO2017151818A2
(en)
|
2016-03-02 |
2017-09-08 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
IL262366B2
(en)
|
2016-04-15 |
2024-07-01 |
Alpine Immune Sciences Inc |
Immunomodulatory proteins and CD80 variants and their uses
|
|
AU2017250358B2
(en)
|
2016-04-15 |
2023-06-01 |
Alpine Immune Sciences, Inc. |
ICOS ligand variant immunomodulatory proteins and uses thereof
|
|
EP3491013A1
(en)
|
2016-07-28 |
2019-06-05 |
Alpine Immune Sciences, Inc. |
Cd155 variant immunomodulatory proteins and uses thereof
|
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
|
MA46534A
(fr)
|
2016-10-14 |
2019-08-21 |
Xencor Inc |
Protéines de fusion fc hétérodimères il15/il15r
|
|
SG11201903407XA
(en)
|
2016-10-20 |
2019-05-30 |
Alpine Immune Sciences Inc |
Secretable variant immunomodulatory proteins and engineered cell therapy
|
|
HUE064136T2
(hu)
|
2017-03-16 |
2024-02-28 |
Alpine Immune Sciences Inc |
PD-L1 variáns immunmódosító fehérjék és alkalmazásuk
|
|
US11732022B2
(en)
|
2017-03-16 |
2023-08-22 |
Alpine Immune Sciences, Inc. |
PD-L2 variant immunomodulatory proteins and uses thereof
|
|
KR20250083578A
(ko)
|
2017-03-16 |
2025-06-10 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Cd80 변이체 면역조절 단백질 및 그의 용도
|
|
CA3077509A1
(en)
|
2017-10-10 |
2019-04-18 |
Alpine Immune Sciences, Inc. |
Ctla-4 variant immunomodulatory proteins and uses thereof
|
|
IL320945A
(en)
|
2017-10-18 |
2025-07-01 |
Alpine Immune Sciences Inc |
Immunomodulatory proteins, ligands for ICOs, and compositions and methods related thereto
|
|
AU2019205273B2
(en)
|
2018-01-03 |
2024-04-04 |
Alpine Immune Sciences, Inc. |
Multi-domain immunomodulatory proteins and methods of use thereof
|
|
US12065476B2
(en)
|
2018-06-15 |
2024-08-20 |
Alpine Immune Sciences, Inc. |
PD-1 variant immunomodulatory proteins and uses thereof
|
|
JP2022501361A
(ja)
|
2018-09-19 |
2022-01-06 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
バリアントｃｄ８０融合タンパク質および関連構築物の方法および使用
|
|
JP2023517044A
(ja)
|
2020-03-09 |
2023-04-21 |
ファイザー・インク |
融合タンパク質およびその使用
|
|
EP4490173A1
(en)
|
2022-03-07 |
2025-01-15 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses
|