JP2018512856A - 調整可能な親和性を有する免疫調節タンパク質 - Google Patents

調整可能な親和性を有する免疫調節タンパク質 Download PDF

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JP2018512856A
JP2018512856A JP2017553418A JP2017553418A JP2018512856A JP 2018512856 A JP2018512856 A JP 2018512856A JP 2017553418 A JP2017553418 A JP 2017553418A JP 2017553418 A JP2017553418 A JP 2017553418A JP 2018512856 A JP2018512856 A JP 2018512856A
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protein
affinity
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JP2018512856A5 (enExample
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ライアン スワンソン
ライアン スワンソン
マイケル コルナッカー
マイケル コルナッカー
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アルパイン イミューン サイエンシズ インコーポレイテッド
アルパイン イミューン サイエンシズ インコーポレイテッド
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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JP2017553418A 2015-04-17 2016-04-15 調整可能な親和性を有する免疫調節タンパク質 Pending JP2018512856A (ja)

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US201562149437P 2015-04-17 2015-04-17
US62/149,437 2015-04-17
US201562218534P 2015-09-14 2015-09-14
US62/218,534 2015-09-14
PCT/US2016/027995 WO2016168771A2 (en) 2015-04-17 2016-04-15 Immunomodulatory proteins with tunable affinities

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JP2018534245A (ja) * 2015-09-14 2018-11-22 アルパイン イミューン サイエンシズ インコーポレイテッド 調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法
JP2022510276A (ja) * 2018-11-30 2022-01-26 アルパイン イミューン サイエンシズ インコーポレイテッド Ｃｄ８６バリアント免疫調節タンパク質およびその使用

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* Cited by examiner, † Cited by third party
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JP2018534245A (ja) * 2015-09-14 2018-11-22 アルパイン イミューン サイエンシズ インコーポレイテッド 調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法
JP2022510276A (ja) * 2018-11-30 2022-01-26 アルパイン イミューン サイエンシズ インコーポレイテッド Ｃｄ８６バリアント免疫調節タンパク質およびその使用
JP2025060939A (ja) * 2018-11-30 2025-04-10 アルパイン イミューン サイエンシズ インコーポレイテッド Ｃｄ８６バリアント免疫調節タンパク質およびその使用
JP7713886B2 (ja) 2018-11-30 2025-07-28 アルパイン イミューン サイエンシズ インコーポレイテッド Ｃｄ８６バリアント免疫調節タンパク質およびその使用

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