JP2015512448A5 - - Google Patents
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- JP2015512448A5 JP2015512448A5 JP2015504698A JP2015504698A JP2015512448A5 JP 2015512448 A5 JP2015512448 A5 JP 2015512448A5 JP 2015504698 A JP2015504698 A JP 2015504698A JP 2015504698 A JP2015504698 A JP 2015504698A JP 2015512448 A5 JP2015512448 A5 JP 2015512448A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- antigen
- hyo
- porcine
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000036639 antigens Human genes 0.000 claims description 30
- 108091007433 antigens Proteins 0.000 claims description 30
- 239000000427 antigen Substances 0.000 claims description 24
- 241001673669 Porcine circovirus 2 Species 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 17
- 239000002671 adjuvant Substances 0.000 claims description 14
- 241000282898 Sus scrofa Species 0.000 claims description 12
- 230000002163 immunogen Effects 0.000 claims description 12
- 241000282887 Suidae Species 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 10
- 244000005700 microbiome Species 0.000 claims description 10
- 241000700605 Viruses Species 0.000 claims description 9
- 201000010099 disease Diseases 0.000 claims description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 9
- 230000001681 protective effect Effects 0.000 claims description 9
- 230000001413 cellular effect Effects 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 108060003951 Immunoglobulin Proteins 0.000 claims description 7
- 102000018358 immunoglobulin Human genes 0.000 claims description 7
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 claims description 6
- 241000204045 Mycoplasma hyopneumoniae Species 0.000 claims description 6
- 101710113540 ORF2 protein Proteins 0.000 claims description 6
- 241000702619 Porcine parvovirus Species 0.000 claims description 6
- 101710090523 Putative movement protein Proteins 0.000 claims description 6
- 241000725681 Swine influenza virus Species 0.000 claims description 6
- 241000960387 Torque teno virus Species 0.000 claims description 6
- 230000028993 immune response Effects 0.000 claims description 6
- 244000052769 pathogen Species 0.000 claims description 6
- 241000202938 Mycoplasma hyorhinis Species 0.000 claims description 5
- 241000194021 Streptococcus suis Species 0.000 claims description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 241000606748 Actinobacillus pleuropneumoniae Species 0.000 claims description 3
- 241000588779 Bordetella bronchiseptica Species 0.000 claims description 3
- 241001148534 Brachyspira Species 0.000 claims description 3
- 206010012735 Diarrhoea Diseases 0.000 claims description 3
- 241000710188 Encephalomyocarditis virus Species 0.000 claims description 3
- 241000709661 Enterovirus Species 0.000 claims description 3
- 241000588724 Escherichia coli Species 0.000 claims description 3
- 208000005577 Gastroenteritis Diseases 0.000 claims description 3
- 241000606790 Haemophilus Species 0.000 claims description 3
- 241001148567 Lawsonia intracellularis Species 0.000 claims description 3
- 241000204031 Mycoplasma Species 0.000 claims description 3
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims description 3
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 claims description 3
- 241000711493 Porcine respiratory coronavirus Species 0.000 claims description 3
- 206010037660 Pyrexia Diseases 0.000 claims description 3
- 241000702670 Rotavirus Species 0.000 claims description 3
- 241000607142 Salmonella Species 0.000 claims description 3
- 208000015181 infectious disease Diseases 0.000 claims description 3
- 230000002458 infectious effect Effects 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 241001533384 Circovirus Species 0.000 claims description 2
- 241000928435 Porcine circovirus 1 Species 0.000 claims description 2
- 101710120037 Toxin CcdB Proteins 0.000 claims description 2
- 229930003427 Vitamin E Natural products 0.000 claims description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
- 230000003053 immunization Effects 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 241000701447 unidentified baculovirus Species 0.000 claims description 2
- 229940046009 vitamin E Drugs 0.000 claims description 2
- 235000019165 vitamin E Nutrition 0.000 claims description 2
- 239000011709 vitamin E Substances 0.000 claims description 2
- 229960005486 vaccine Drugs 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 3
- 241000701022 Cytomegalovirus Species 0.000 claims 1
- 241000589902 Leptospira Species 0.000 claims 1
- 241000606860 Pasteurella Species 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 244000144972 livestock Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 description 4
- 241000202934 Mycoplasma pneumoniae Species 0.000 description 2
- 241000606856 Pasteurella multocida Species 0.000 description 2
- 241001354013 Salmonella enterica subsp. enterica serovar Enteritidis Species 0.000 description 2
- 241001485053 Suid betaherpesvirus 2 Species 0.000 description 2
- 229940051027 pasteurella multocida Drugs 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261620165P | 2012-04-04 | 2012-04-04 | |
| US61/620,165 | 2012-04-04 | ||
| PCT/US2013/035083 WO2013152081A1 (en) | 2012-04-04 | 2013-04-03 | Mycoplasma hyopneumoniae vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512448A JP2015512448A (ja) | 2015-04-27 |
| JP2015512448A5 true JP2015512448A5 (https=) | 2016-06-02 |
| JP6271502B2 JP6271502B2 (ja) | 2018-01-31 |
Family
ID=48087777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015504698A Active JP6271502B2 (ja) | 2012-04-04 | 2013-04-03 | マイコプラズマ・ハイオニューモニエワクチン |
Country Status (31)
| Country | Link |
|---|---|
| US (5) | US9120859B2 (https=) |
| EP (2) | EP2833908B1 (https=) |
| JP (1) | JP6271502B2 (https=) |
| KR (1) | KR101747507B1 (https=) |
| CN (1) | CN104271154B (https=) |
| AR (1) | AR090611A1 (https=) |
| AU (1) | AU2013243535C1 (https=) |
| BR (1) | BR112014024533B1 (https=) |
| CA (1) | CA2869603C (https=) |
| CL (1) | CL2014002674A1 (https=) |
| CO (1) | CO7160026A2 (https=) |
| CR (1) | CR20140436A (https=) |
| CY (1) | CY1124982T1 (https=) |
| DK (1) | DK2833908T3 (https=) |
| ES (1) | ES2905302T3 (https=) |
| GT (1) | GT201400210A (https=) |
| HR (2) | HRP20220175T1 (https=) |
| HU (1) | HUE058321T2 (https=) |
| LT (1) | LT2833908T (https=) |
| MX (2) | MX336504B (https=) |
| MY (1) | MY166792A (https=) |
| NI (1) | NI201400117A (https=) |
| PH (1) | PH12014502250A1 (https=) |
| PL (1) | PL2833908T3 (https=) |
| PT (1) | PT2833908T (https=) |
| RS (1) | RS62881B1 (https=) |
| RU (1) | RU2644254C2 (https=) |
| SI (1) | SI2833908T1 (https=) |
| TW (1) | TWI602575B (https=) |
| UA (1) | UA114502C2 (https=) |
| WO (1) | WO2013152081A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8546149B2 (en) | 2010-08-27 | 2013-10-01 | Intervet Inc. | Potency test for vaccine formulations |
| UA114503C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| UA114504C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| SG11201505086QA (en) * | 2012-12-28 | 2015-07-30 | Boehringer Ingelheim Vetmed | Immunogenic composition comprising mycoplasma antigens |
| PT2938747T (pt) | 2012-12-28 | 2019-08-01 | Boehringer Ingelheim Vetmedica Gmbh | Método de preparação de uma vacina de micoplasma |
| ES2882374T3 (es) | 2013-05-08 | 2021-12-01 | Pharmgate Biologics Inc | Vacuna para PCV2 y micoplasma |
| CN104248759B (zh) * | 2013-11-19 | 2017-05-10 | 普莱柯生物工程股份有限公司 | 一种疫苗组合物及其制备方法和应用 |
| CN105792841B (zh) * | 2013-11-21 | 2019-07-26 | 财团法人农业科技研究院 | 防治霉浆菌感染的组合物 |
| WO2015187947A1 (en) * | 2014-06-04 | 2015-12-10 | Izard Ryan | Methods and compositions for orally dosing postnatal swine |
| BR102014014727B1 (pt) * | 2014-06-16 | 2018-04-03 | Ouro Fino Saúde Animal Ltda | COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, GENE SINTÉTICO CODIFICANTE DO COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, COMPOSIÇÃO ANTIGÊNICA, PROCESSO DE OBTENÇÃO DE UM COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae |
| CN104324370B (zh) * | 2014-09-30 | 2019-12-20 | 普莱柯生物工程股份有限公司 | 疫苗组合物及其制备方法和应用 |
| RU2018127200A (ru) * | 2016-01-07 | 2020-02-07 | Университейт Гент | Вакцинные штаммы brachyspira hyodysenteriae |
| WO2017162727A1 (en) * | 2016-03-23 | 2017-09-28 | Intervet International B.V. | A combination vaccine against pcv2 and prrs virus infection comprising albumin |
| CN106497850B (zh) * | 2016-12-20 | 2019-10-29 | 天津瑞普生物技术股份有限公司 | 一种纯化猪肺炎支原体的方法 |
| EP3558351B1 (en) | 2016-12-23 | 2022-01-26 | Intervet International B.V. | Combination vaccine for swine |
| US11744883B2 (en) * | 2017-12-22 | 2023-09-05 | Hipra Scientific, S.L.U. | Intradermal combination vaccine against mycoplasma and porcine circovirus |
| US20220235313A1 (en) | 2019-06-10 | 2022-07-28 | ELANCO US, Inc. | Mycoplasma media formulations |
| WO2021018806A1 (en) * | 2019-07-26 | 2021-02-04 | Ceva Sante Animale | Igg-depleted porcine serum and the uses thereof |
| JP7657287B2 (ja) | 2020-07-24 | 2025-04-04 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 組合せブタワクチン |
| KR20220168102A (ko) | 2021-06-15 | 2022-12-22 | 엘지전자 주식회사 | 조리기기 |
| KR20220168099A (ko) | 2021-06-15 | 2022-12-22 | 엘지전자 주식회사 | 조리기기 |
| KR20220168098A (ko) | 2021-06-15 | 2022-12-22 | 엘지전자 주식회사 | 조리기기 |
| KR20220168101A (ko) | 2021-06-15 | 2022-12-22 | 엘지전자 주식회사 | 조리기기 |
| KR20220168097A (ko) | 2021-06-15 | 2022-12-22 | 엘지전자 주식회사 | 조리기기 |
| KR20220168100A (ko) | 2021-06-15 | 2022-12-22 | 엘지전자 주식회사 | 조리기기 |
| CN114134098A (zh) * | 2021-12-15 | 2022-03-04 | 成都史纪生物制药有限公司 | 一种猪肺炎支原体的灭活方法 |
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| TWI449533B (zh) | 2008-04-18 | 2014-08-21 | Intervet Int Bv | 防備胞內勞森菌（Ｌａｗｓｏｎｉａ ｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）、豬肺炎黴漿菌（Ｍｙｃｏｐｌａｓｍａ ｈｙｏｐｎｅｕｍｏｎｉａｅ）及豬環狀病毒（Ｐｏｒｃｉｎｅ ｃｉｒｃｏ ｖｉｒｕｓ）用疫苗 |
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| PL2569007T3 (pl) | 2010-05-11 | 2016-04-29 | Intervet Int Bv | Szczepionka przeciwko Mycoplasma Hyopneumoniae, odpowiednia do podawania w obecności przeciwciał pochodzących od matki |
| HUE028877T2 (en) * | 2010-08-27 | 2017-01-30 | Intervet Int Bv | Test of biological activity of vaccine formulation |
| US8546149B2 (en) | 2010-08-27 | 2013-10-01 | Intervet Inc. | Potency test for vaccine formulations |
| UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
| UA115053C2 (uk) | 2012-03-07 | 2017-09-11 | Сева Санте Анімаль | Композиція, що містить антиген і ліпополісахарид у формі масло-в-воді, та спосіб її використання (варіанти) |
| UA114503C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| UA114504C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| US9120859B2 (en) * | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| CA2872789C (en) * | 2012-05-17 | 2019-09-03 | Zoetis Llc | Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning |
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