JP2015512450A5 - - Google Patents
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- Publication number
- JP2015512450A5 JP2015512450A5 JP2015504701A JP2015504701A JP2015512450A5 JP 2015512450 A5 JP2015512450 A5 JP 2015512450A5 JP 2015504701 A JP2015504701 A JP 2015504701A JP 2015504701 A JP2015504701 A JP 2015504701A JP 2015512450 A5 JP2015512450 A5 JP 2015512450A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- hyo
- antigen
- pcv2
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000036639 antigens Human genes 0.000 claims description 36
- 108091007433 antigens Proteins 0.000 claims description 36
- 239000000427 antigen Substances 0.000 claims description 31
- 241001673669 Porcine circovirus 2 Species 0.000 claims description 24
- 241000700605 Viruses Species 0.000 claims description 24
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims description 22
- 239000002671 adjuvant Substances 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 11
- 230000002163 immunogen Effects 0.000 claims description 9
- 108060003951 Immunoglobulin Proteins 0.000 claims description 7
- 102000018358 immunoglobulin Human genes 0.000 claims description 7
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 claims description 6
- 101710113540 ORF2 protein Proteins 0.000 claims description 6
- 101710090523 Putative movement protein Proteins 0.000 claims description 6
- 230000001413 cellular effect Effects 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 241000204045 Mycoplasma hyopneumoniae Species 0.000 claims description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 230000028993 immune response Effects 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 241001533384 Circovirus Species 0.000 claims description 2
- 241000928435 Porcine circovirus 1 Species 0.000 claims description 2
- 101710120037 Toxin CcdB Proteins 0.000 claims description 2
- 229930003427 Vitamin E Natural products 0.000 claims description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
- 230000003053 immunization Effects 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 241000701447 unidentified baculovirus Species 0.000 claims description 2
- 229940046009 vitamin E Drugs 0.000 claims description 2
- 235000019165 vitamin E Nutrition 0.000 claims description 2
- 239000011709 vitamin E Substances 0.000 claims description 2
- 229960005486 vaccine Drugs 0.000 claims 4
- 241000282887 Suidae Species 0.000 claims 3
- 241000282898 Sus scrofa Species 0.000 claims 3
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 241000202347 Porcine circovirus Species 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 244000144972 livestock Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 description 1
- 241000202934 Mycoplasma pneumoniae Species 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261620189P | 2012-04-04 | 2012-04-04 | |
| US61/620,189 | 2012-04-04 | ||
| PCT/US2013/035091 WO2013152086A1 (en) | 2012-04-04 | 2013-04-03 | Pcv/mycoplasma hyopneumoniae/prrs combination vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512450A JP2015512450A (ja) | 2015-04-27 |
| JP2015512450A5 true JP2015512450A5 (https=) | 2016-06-02 |
| JP6271504B2 JP6271504B2 (ja) | 2018-01-31 |
Family
ID=48140160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015504701A Active JP6271504B2 (ja) | 2012-04-04 | 2013-04-03 | Ｐｃｖ／マイコプラズマ・ハイオニューモニエ／ｐｒｒｓ混合ワクチン |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US9125886B2 (https=) |
| EP (2) | EP2833909B1 (https=) |
| JP (1) | JP6271504B2 (https=) |
| KR (1) | KR101808903B1 (https=) |
| AR (1) | AR090614A1 (https=) |
| AU (1) | AU2013243540C1 (https=) |
| BR (1) | BR112014024775B1 (https=) |
| CA (1) | CA2869601C (https=) |
| CL (1) | CL2014002676A1 (https=) |
| CO (1) | CO7160027A2 (https=) |
| CR (1) | CR20140438A (https=) |
| CY (1) | CY1121578T1 (https=) |
| DK (1) | DK2833909T3 (https=) |
| ES (1) | ES2719483T3 (https=) |
| GT (1) | GT201400212A (https=) |
| HR (2) | HRP20140956A2 (https=) |
| HU (1) | HUE042405T2 (https=) |
| LT (1) | LT2833909T (https=) |
| MX (2) | MX336502B (https=) |
| MY (1) | MY168549A (https=) |
| NI (1) | NI201400118A (https=) |
| PH (1) | PH12014502252B1 (https=) |
| PL (1) | PL2833909T3 (https=) |
| PT (1) | PT2833909T (https=) |
| RS (1) | RS58480B1 (https=) |
| RU (1) | RU2644256C2 (https=) |
| SI (1) | SI2833909T1 (https=) |
| TR (1) | TR201905176T4 (https=) |
| TW (1) | TWI504406B (https=) |
| UA (1) | UA114504C2 (https=) |
| WO (1) | WO2013152086A1 (https=) |
| ZA (1) | ZA201407133B (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2027873B8 (en) | 2001-07-02 | 2015-11-11 | Zoetis Services LLC | One dose vaccination with mycoplasma hyopneumoniae |
| US8546149B2 (en) | 2010-08-27 | 2013-10-01 | Intervet Inc. | Potency test for vaccine formulations |
| US9120859B2 (en) * | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| UA114503C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| MX361273B (es) | 2012-12-28 | 2018-12-03 | Boehringer Ingelheim Vetmedica Gmbh | Metodo para obtener una vacuna de mycoplasma. |
| AU2013370982C9 (en) * | 2012-12-28 | 2019-01-24 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic composition comprising mycoplasma antigens |
| US9649370B2 (en) | 2013-05-08 | 2017-05-16 | Protatek International, Inc. | Vaccine for PCV2 and mycoplasma |
| BR112016010427B1 (pt) * | 2013-11-21 | 2020-06-02 | Agricultural Technology Research Institute | Composição para prevenir infecção por mycoplasma spp., vetor de expressão, e método para prepararantígeno solúvel |
| RU2655615C1 (ru) * | 2013-12-03 | 2018-05-29 | Интервет Интернэшнл Б.В. | Вакцина для свиней против prrs и lawsonia intracellularis |
| CN105848675A (zh) * | 2013-12-03 | 2016-08-10 | 英特维特国际股份有限公司 | 抗猪圆环病毒2型的疫苗 |
| CN104056265B (zh) * | 2014-07-11 | 2016-04-27 | 江苏南农高科技股份有限公司 | 猪圆环病毒2型、猪繁殖与呼吸综合征二联疫苗及其制备方法 |
| WO2016038194A1 (en) * | 2014-09-12 | 2016-03-17 | Intervet International B.V. | Vaccine for use in protecting a pig against porcine endemic diarrhea virus |
| CN107073102B (zh) * | 2014-09-12 | 2021-06-25 | 英特维特国际股份有限公司 | 用于保护母猪的后代免于猪流行性腹泻病毒的疫苗 |
| BR112017012220A2 (pt) * | 2014-12-11 | 2018-01-30 | Intervet Int Bv | processos para preparar uma composição de antígeno e uma vacina, composição de antígeno, vacina, usos de uma composição de antígeno e de uma vacina, e, método para prevenção ou redução de infecção por um vírus em suíno e sinais associados à doença. |
| JP6839714B2 (ja) * | 2015-12-28 | 2021-03-10 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | Ｍ Ｈｙｏ多重ワクチン及びその使用 |
| EP3432920A1 (en) | 2016-03-23 | 2019-01-30 | Intervet International B.V. | A vaccine for intradermal application against pcv2 and prrs virus infection |
| JP6907227B2 (ja) * | 2016-03-23 | 2021-07-21 | インターベット インターナショナル ベー． フェー． | Ｐｃｖ２ウイルス及びマイコプラズマ・ハイオニューモニエ感染症に対する混合ワクチン |
| JP7009445B2 (ja) * | 2016-08-09 | 2022-02-10 | アグリカルチュラル テクノロジー リサーチ インスティテュート | マイコプラズマ・ヒオリニス感染を予防治療する組成物 |
| MX2019006992A (es) * | 2016-12-14 | 2019-08-29 | Zoetis Services Llc | Vacunacion eficaz contra cepas europeas del virus del sindrome reproductivo y respiratorio porcino (prrs) previo al destete. |
| ES2906854T3 (es) * | 2016-12-23 | 2022-04-20 | Intervet Int Bv | Vacuna combinada para cerdos |
| US11311614B2 (en) | 2017-04-13 | 2022-04-26 | Intervet Inc. | Vaccines containing swine pathogens for associated non-mixed use |
| CN109280642B (zh) * | 2017-07-21 | 2022-07-22 | 浙江海隆生物科技有限公司 | CHO细胞株及其制备方法和使用该CHO细胞株制备猪圆环病毒2型Cap蛋白及其应用 |
| BR112020011044A2 (pt) | 2017-12-04 | 2020-11-17 | Intervet International B.V. | vacinação com partículas de replicon e adjuvante de óleo |
| JP7510874B2 (ja) * | 2017-12-22 | 2024-07-04 | ヒプラ シエンティフィック エセ．エレ．ウ． | マイコプラズマ及びブタサーコウイルスに対する皮内混合ワクチン |
| MX420109B (es) | 2018-03-26 | 2025-02-10 | Boehringer Ingelheim Animal Health Usa Inc | Metodo para producir una composicion inmunogenica |
| KR102769557B1 (ko) * | 2021-11-19 | 2025-02-20 | 주식회사 이노백 | 신규한 재조합 돼지 써코바이러스 2형 단백질 및 이의 용도 |
| CN119913202B (zh) * | 2025-01-15 | 2025-09-19 | 北京华夏兴洋生物科技有限公司 | 用于制备猪三联疫苗的重组载体、重组病毒及其应用 |
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| TWI449533B (zh) | 2008-04-18 | 2014-08-21 | Intervet Int Bv | 防備胞內勞森菌（Ｌａｗｓｏｎｉａ ｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）、豬肺炎黴漿菌（Ｍｙｃｏｐｌａｓｍａ ｈｙｏｐｎｅｕｍｏｎｉａｅ）及豬環狀病毒（Ｐｏｒｃｉｎｅ ｃｉｒｃｏ ｖｉｒｕｓ）用疫苗 |
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| BR112013004594B1 (pt) | 2010-08-27 | 2020-07-28 | Intervet International B. V. | método para a determinação de um conteúdo de antígeno |
| US8546149B2 (en) | 2010-08-27 | 2013-10-01 | Intervet Inc. | Potency test for vaccine formulations |
| UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
| BR112014022067B1 (pt) | 2012-03-07 | 2022-05-31 | Ceva Sante Animale | Composição compreendendo antígeno e lipopolissacarídeo |
| UA114503C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| UA114504C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| US9120859B2 (en) * | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
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2013
- 2013-03-04 UA UAA201410839A patent/UA114504C2/uk unknown
- 2013-03-26 US US13/850,331 patent/US9125886B2/en active Active
- 2013-04-02 TW TW102111963A patent/TWI504406B/zh active
- 2013-04-03 RS RS20190354A patent/RS58480B1/sr unknown
- 2013-04-03 EP EP13717118.7A patent/EP2833909B1/en not_active Revoked
- 2013-04-03 EP EP19155397.3A patent/EP3508217A1/en active Pending
- 2013-04-03 HR HRP20140956AA patent/HRP20140956A2/hr not_active Application Discontinuation
- 2013-04-03 MX MX2014012016A patent/MX336502B/es unknown
- 2013-04-03 AU AU2013243540A patent/AU2013243540C1/en not_active Ceased
- 2013-04-03 BR BR112014024775-7A patent/BR112014024775B1/pt active IP Right Grant
- 2013-04-03 ES ES13717118T patent/ES2719483T3/es active Active
- 2013-04-03 DK DK13717118.7T patent/DK2833909T3/en active
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- 2013-04-03 CA CA2869601A patent/CA2869601C/en active Active
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- 2013-04-03 JP JP2015504701A patent/JP6271504B2/ja active Active
- 2013-04-03 TR TR2019/05176T patent/TR201905176T4/tr unknown
- 2013-04-03 HU HUE13717118A patent/HUE042405T2/hu unknown
- 2013-04-03 KR KR1020147030871A patent/KR101808903B1/ko active Active
- 2013-04-03 SI SI201331404T patent/SI2833909T1/sl unknown
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- 2013-04-03 RU RU2014140108A patent/RU2644256C2/ru active
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2014
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2015
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