TR201905176T4 - Pcv/mycoplasma hyopneumonıae/prrs kombinasyon aşısı. - Google Patents

Pcv/mycoplasma hyopneumonıae/prrs kombinasyon aşısı. Download PDF

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Publication number
TR201905176T4
TR201905176T4 TR2019/05176T TR201905176T TR201905176T4 TR 201905176 T4 TR201905176 T4 TR 201905176T4 TR 2019/05176 T TR2019/05176 T TR 2019/05176T TR 201905176 T TR201905176 T TR 201905176T TR 201905176 T4 TR201905176 T4 TR 201905176T4
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TR
Turkey
Prior art keywords
mycoplasma hyopneumoniae
pcv
combination vaccine
antigen
prrs combination
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TR2019/05176T
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English (en)
Inventor
P Nitzel Gregory
E Galvin Jeffrey
Keith Garrett John
R Ii Kulawik James
L Ricker Tracy
Marie Smutzer Megan
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Zoetis Services Llc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48140160&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR201905176(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of TR201905176T4 publication Critical patent/TR201905176T4/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
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  • Virology (AREA)
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  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Bu buluş, bir Mycoplasma hyopneumoniae (M.hyo) tam hücre preparasyonunun çözülebilir bir bölümünü; bir domuz sirkovirüsü tip 2 (PCV2) antijeni; ve bir PRRS virüsü antijeni içeren bir trivalent immünojenik kompozisyon sağlar; burada M.hyo preparasyonunun çözülebilir bölümü, hem (i) IgG hem de (ii) immünoglobüline bağlı antijenden müteşekkil immünokomplekslerden önemli ölçüde muaftır.
TR2019/05176T 2012-04-04 2013-04-03 Pcv/mycoplasma hyopneumonıae/prrs kombinasyon aşısı. TR201905176T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261620189P 2012-04-04 2012-04-04

Publications (1)

Publication Number Publication Date
TR201905176T4 true TR201905176T4 (tr) 2019-05-21

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TR2019/05176T TR201905176T4 (tr) 2012-04-04 2013-04-03 Pcv/mycoplasma hyopneumonıae/prrs kombinasyon aşısı.

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US (2) US9125886B2 (tr)
EP (2) EP2833909B1 (tr)
JP (1) JP6271504B2 (tr)
KR (1) KR101808903B1 (tr)
AR (1) AR090614A1 (tr)
AU (1) AU2013243540C1 (tr)
BR (1) BR112014024775B1 (tr)
CA (1) CA2869601C (tr)
CL (1) CL2014002676A1 (tr)
CO (1) CO7160027A2 (tr)
CR (1) CR20140438A (tr)
CY (1) CY1121578T1 (tr)
DK (1) DK2833909T3 (tr)
ES (1) ES2719483T3 (tr)
GT (1) GT201400212A (tr)
HK (1) HK1207283A1 (tr)
HR (2) HRP20140956A2 (tr)
HU (1) HUE042405T2 (tr)
LT (1) LT2833909T (tr)
MX (2) MX336502B (tr)
MY (1) MY168549A (tr)
NI (1) NI201400118A (tr)
PH (1) PH12014502252A1 (tr)
PL (1) PL2833909T3 (tr)
PT (1) PT2833909T (tr)
RS (1) RS58480B1 (tr)
RU (1) RU2644256C2 (tr)
SI (1) SI2833909T1 (tr)
TR (1) TR201905176T4 (tr)
TW (1) TWI504406B (tr)
UA (1) UA114504C2 (tr)
WO (1) WO2013152086A1 (tr)
ZA (1) ZA201407133B (tr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK288010B6 (sk) 2001-07-02 2012-10-02 Pfizer Products Inc. Use of Mycoplasma hyopneumoniae for the manufacture of a medicament
US8546149B2 (en) 2010-08-27 2013-10-01 Intervet Inc. Potency test for vaccine formulations
US9120859B2 (en) * 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114503C2 (uk) * 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
WO2014105671A1 (en) 2012-12-28 2014-07-03 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition comprising mycoplasma antigens
EA032772B1 (ru) 2012-12-28 2019-07-31 Бёрингер Ингельхайм Ветмедика Гмбх Способ получения иммуногенной композиции, предназначенной для лечения и/или профилактики вызываемых микоплазмами инфекций у субъекта
EP2994162B1 (en) 2013-05-08 2021-04-07 Pharmgate Biologics Inc. Vaccine for pcv2 and mycoplasma
MX368864B (es) * 2013-11-21 2019-10-18 Agricultural Tech Res Inst Composicion para prevenir infeccion por mycoplasma spp.
DK3076996T3 (en) * 2013-12-03 2020-03-09 Intervet Int Bv Vaccine mod porcint circovirus type 2
EP3076997B1 (en) * 2013-12-03 2018-08-29 Intervet International B.V. Swine vaccine against prrs and lawsonia intracellularis
CN104056265B (zh) * 2014-07-11 2016-04-27 江苏南农高科技股份有限公司 猪圆环病毒2型、猪繁殖与呼吸综合征二联疫苗及其制备方法
WO2016038194A1 (en) * 2014-09-12 2016-03-17 Intervet International B.V. Vaccine for use in protecting a pig against porcine endemic diarrhea virus
WO2016038197A1 (en) * 2014-09-12 2016-03-17 Intervet International B.V. Vaccine for use in protecting offspring of a sow against porcine endemic diarrhea virus
CN106999567B (zh) * 2014-12-11 2021-08-31 英特维特国际股份有限公司 用于即用型PCV2/M.hyo组合疫苗的方法
RU2018127403A (ru) * 2015-12-28 2020-01-30 Мериал, Инк. Поливалентная вакцина против hyo и ее применение
CN108697782A (zh) * 2016-03-23 2018-10-23 英特维特国际股份有限公司 针对pcv2病毒和猪肺炎支原体感染的组合疫苗
RU2746127C2 (ru) 2016-03-23 2021-04-07 Интервет Интернэшнл Б.В. Вакцина для внутрикожного применения против инфекции вируса pcv2 и prrs
JP7009445B2 (ja) * 2016-08-09 2022-02-10 アグリカルチュラル テクノロジー リサーチ インスティテュート マイコプラズマ・ヒオリニス感染を予防治療する組成物
RU2755345C2 (ru) * 2016-12-14 2021-09-15 Зоэтис Сервисиз Ллс Эффективная вакцинация против европейских штаммов вируса репродуктивного и респираторного синдрома (prrs) до отлучения от матери
RU2761453C2 (ru) * 2016-12-23 2021-12-08 Интервет Интернэшнл Б.В. Комбинированная вакцина для свиней
US11311614B2 (en) 2017-04-13 2022-04-26 Intervet Inc. Vaccines containing swine pathogens for associated non-mixed use
CN109280642B (zh) * 2017-07-21 2022-07-22 浙江海隆生物科技有限公司 CHO细胞株及其制备方法和使用该CHO细胞株制备猪圆环病毒2型Cap蛋白及其应用
EP3727432A1 (en) 2017-12-22 2020-10-28 Hipra Scientific, S.L.U. Intradermal combination vaccine against mycoplasma and porcine circovirus
KR20200135505A (ko) * 2018-03-26 2020-12-02 베링거 인겔하임 애니멀 헬스 유에스에이 인크. 면역원성 조성물의 제조방법

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4606918A (en) 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4681870A (en) * 1985-01-11 1987-07-21 Imre Corporation Protein A-silica immunoadsorbent and process for its production
JPH0832637B2 (ja) 1985-02-14 1996-03-29 アクゾ・エヌ・ヴエー 合成免疫原
US5084269A (en) 1986-11-06 1992-01-28 Kullenberg Fred W Adjuvant for dose treatment with antigens
DE3875762T2 (de) 1987-03-17 1993-05-13 Akzo Nv Adjuvanzienmischung.
US5252328A (en) * 1987-03-26 1993-10-12 Martin Marietta Energy Systems, Inc. Mycoplasma hyopneumoniae antigen and uses therefor
EP0283840A3 (en) 1987-03-26 1989-08-09 Ml Technology Ventures, L.P. Mycoplasma hyopneumoniae antigen and uses therefor
EP0513861B1 (en) 1987-11-03 1997-02-26 Syntex (U.S.A.) Inc. Vaccine adjuvant comprising a tetra-polyol
US4985243A (en) 1988-01-20 1991-01-15 Ml Technology Ventures, L.P. Composition and method for protecting against diseases caused by microorganisms
US5240706A (en) 1989-04-07 1993-08-31 Ml Technology Ventures, L.P. Intranasal administration of Mycoplasma hyopneumoniae antigen
ZA906806B (en) 1989-08-31 1991-06-26 Ici Australia Operations Plants
WO1991018627A1 (en) 1990-05-29 1991-12-12 Smithkline Beecham Corporation Swine pneumonia vaccine and method for the preparation thereof
US6113916A (en) 1990-05-29 2000-09-05 American Cyanamid Company Method of enhancing cell mediated immune responses
US5695769A (en) 1990-06-13 1997-12-09 Pfizer Inc. Pasteurella multocida toxoid vaccines
US5565205A (en) 1990-08-16 1996-10-15 Solvay Animal Health, Inc. Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof
HU218431B (hu) 1991-06-06 2000-08-28 Stichting Centraal Diergeneeskundig Instituut A rejtélyes sertésvészt okozó Lelystad-vírus, a vírusból származtatható polipeptidek, antigének és nukleinsavak és rejtélyes sertésvész elleni vakcinakészítmények
US5269315A (en) 1991-08-16 1993-12-14 The Regents Of The University Of California Determining the nature of brain lesions by electroencephalography
DE69214657T4 (de) 1991-08-26 2003-07-17 Boehringer Ingelheim Vetmed Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)
EP0610250B2 (en) 1991-10-14 2008-10-29 Intervet International BV Porcine reproductive respiratory syndrome (prrs) vaccine and diagnostic
JP3043809B2 (ja) 1991-11-15 2000-05-22 ファイザー・インコーポレイテッド グラム陰性菌ワクチン
FR2686097B1 (fr) 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5338543A (en) 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
US5534256A (en) 1992-07-02 1996-07-09 University Of Saskatchewan Haemophilus somnus outer membrane protein extract enriched with iron-regulated proteins
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6251397B1 (en) 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
US5695766A (en) 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
ES2074950B1 (es) 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
DE69518316T2 (de) 1994-05-10 2001-03-29 American Home Products Corp., Madison Modifizierter,verbesserter,lebender brsv impfstoff
BE1008978A5 (fr) 1994-12-27 1996-10-01 Solvay Adjuvants pour vaccins.
US5788962A (en) 1995-01-17 1998-08-04 The Curators Of The University Of Missouri DNA sequences coding for mycoplasma hyopneumoniae surface antigens, corresponding proteins and use in vaccines and diagnostic procedures
AUPN178995A0 (en) 1995-03-16 1995-04-13 University Of Melbourne, The Antigen composition
US5820869A (en) 1995-06-07 1998-10-13 American Home Products Corporation Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection
DE19601754A1 (de) 1996-01-19 1997-07-24 Hoechst Ag Dictyocaulus viviparus Antigen zur Diagnose des Lungenwurmbefalls und zur Vakzinierung
US5846735A (en) 1996-04-18 1998-12-08 University Of Iowa Research Foundation Hepatitis C virus Fc-binding function
GB9622159D0 (en) 1996-10-24 1996-12-18 Solvay Sociutu Anonyme Polyanionic polymers as adjuvants for mucosal immunization
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
ATE497004T1 (de) 1996-12-20 2011-02-15 Univ Texas Moraxella catarrhalis antigene uspa1 und uspa2
BR9815321A (pt) 1997-11-26 2002-01-02 Univ Iowa State Res Found Inc Vacina de mycoplasma hyopneumoniae recombinante
US6342231B1 (en) 1998-07-01 2002-01-29 Akzo Nobel N.V. Haemophilus parasuis vaccine and diagnostic
CA2440933A1 (en) 1998-12-22 2000-06-22 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
US6632439B2 (en) 1999-09-29 2003-10-14 Novartis Animal Health, Inc. Fusobacterium necrophorum vaccine and method for making such vaccine
US6585981B1 (en) 2000-07-27 2003-07-01 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae
MY129765A (en) 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
US7018638B2 (en) 2000-12-19 2006-03-28 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
SK288010B6 (sk) 2001-07-02 2012-10-02 Pfizer Products Inc. Use of Mycoplasma hyopneumoniae for the manufacture of a medicament
CN1612749A (zh) * 2001-07-02 2005-05-04 辉瑞产品公司 用于减弱牲畜体内牛支原体肺炎的猪肺炎支原体疫苗和方法
US7279166B2 (en) * 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
SI1546357T1 (sl) 2002-06-28 2013-10-30 Iowa State University Research Foundation, Inc. Imunogeni polipeptidi mycoplasma hyopneumoniae
RU2354399C2 (ru) 2003-07-24 2009-05-10 Мериал Лимитед Вакцинная композиция и способ индуцирования иммунологического ответа у животного
JP2008526921A (ja) 2005-01-13 2008-07-24 ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング 改善されたｐｒｒｓワクチン
ES2425228T3 (es) * 2005-09-09 2013-10-14 Intervet International B.V. Vacuna contra el PCV-2
EP1792996A1 (en) 2005-12-01 2007-06-06 Consejo Superior de Investigaciones Cientificas Nucleic acid sequences encoding vaccines against Porcine reproductive and respiratory syndrome virus (PRRSV)
BRPI0620859A2 (pt) 2005-12-29 2011-11-22 Boehringer Ingelheim Vetmedica, Inc. vacina de combinação multivalente contra pcv2
ES2377576T3 (es) * 2006-04-10 2012-03-29 Intervet International Bv Vacuna contra microplasma PRRV
CA2646574C (en) 2006-04-10 2012-08-21 Intervet International B.V. Vaccine against mycoplasma and prrsv
BRPI0820341B1 (pt) 2007-11-06 2021-11-09 Zoetis Services Llc Composição imunogênica para uso na proteção de um animal contra uma doença associada a uma cepa virulenta de mycoplasma hyopneumoniae
BRPI0907438A2 (pt) * 2008-01-23 2015-08-04 Boehringer Ingelheim Vetmed Composições imunogênicas para mycoplasma hyopneumoniae e pcv2 e métodos para produzir tais composições
US8444989B1 (en) 2008-04-18 2013-05-21 Boehringer Ingelheim Vetmedica Gmbh One dose vaccination against mycoplasma infections of pigs
TWI449533B (zh) 2008-04-18 2014-08-21 Intervet Int Bv 防備胞內勞森菌（Ｌａｗｓｏｎｉａ ｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）、豬肺炎黴漿菌（Ｍｙｃｏｐｌａｓｍａ ｈｙｏｐｎｅｕｍｏｎｉａｅ）及豬環狀病毒（Ｐｏｒｃｉｎｅ ｃｉｒｃｏ ｖｉｒｕｓ）用疫苗
CN102256997A (zh) 2008-10-16 2011-11-23 美国辉瑞有限公司 细环病毒分离株和组合物
EP2569007B1 (en) 2010-05-11 2015-10-14 Intervet International B.V. Vaccine against mycoplasma hyopneumoniae, suitable for administration in the presence of maternally derived antibodies
US8546149B2 (en) 2010-08-27 2013-10-01 Intervet Inc. Potency test for vaccine formulations
WO2012025612A1 (en) * 2010-08-27 2012-03-01 Intervet International B.V. Potency test for vaccine formulations
UA108902C2 (uk) 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
WO2013131565A1 (en) 2012-03-07 2013-09-12 Ceva Sante Animale Novel veterinary vaccine
US9120859B2 (en) * 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114504C2 (uk) * 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) * 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae

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