|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
RU2644243C2
(ru)
*
|
2011-10-20 |
2018-02-08 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерные антигенные рецепторы к cd22
|
|
HUE064187T2
(hu)
|
2012-05-25 |
2024-02-28 |
Cellectis |
Eljárás immunterápiára alkalmas allogén és immunszupresszív-rezisztens T-sejt módosítására
|
|
US11142563B2
(en)
|
2012-06-14 |
2021-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule containing modified Fc region
|
|
CA2889055C
(en)
*
|
2012-10-24 |
2024-01-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
M971 chimeric antigen receptors
|
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
|
ES2949648T3
(es)
|
2012-12-20 |
2023-10-02 |
Purdue Research Foundation |
Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
|
|
EP2958943B1
(en)
|
2013-02-20 |
2019-09-11 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
|
WO2014130635A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
HK1220205A1
(zh)
|
2013-03-15 |
2017-04-28 |
Celgene Corporation |
修饰的t淋巴细胞
|
|
US9745368B2
(en)
|
2013-03-15 |
2017-08-29 |
The Trustees Of The University Of Pennsylvania |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
WO2014160627A1
(en)
|
2013-03-25 |
2014-10-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-cd276 polypeptides, proteins, and chimeric antigen receptors
|
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
|
EP3783098A1
(en)
|
2013-05-14 |
2021-02-24 |
Board Of Regents, The University Of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
|
SG11201509609SA
(en)
|
2013-05-24 |
2015-12-30 |
Univ Texas |
Chimeric antigen receptor-targeting monoclonal antibodies
|
|
EP3492094A1
(en)
|
2013-08-30 |
2019-06-05 |
Board of Regents, The University of Texas System |
Administration of kynurenine depleting enzymes for tumor therapy
|
|
ES2960807T3
(es)
|
2013-10-11 |
2024-03-06 |
Us Health |
Anticuerpos contra TEM8 y su uso
|
|
US20160280798A1
(en)
*
|
2013-11-06 |
2016-09-29 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Service |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
|
CN103589742A
(zh)
*
|
2013-11-07 |
2014-02-19 |
申峰 |
嵌合体抗原受体胞内段的基因及其编码蛋白
|
|
CN105940107B
(zh)
|
2013-11-11 |
2021-06-15 |
中外制药株式会社 |
含有改变了抗体可变区的抗原结合分子
|
|
AU2014352638B2
(en)
|
2013-11-25 |
2018-08-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors to control HIV infection
|
|
WO2015090230A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
JP6793902B2
(ja)
|
2013-12-20 |
2020-12-02 |
ノバルティス アーゲー |
調節可能キメラ抗原受容体
|
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
ES2963718T3
(es)
|
2014-01-21 |
2024-04-01 |
Novartis Ag |
Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras
|
|
WO2015120187A1
(en)
|
2014-02-05 |
2015-08-13 |
The University Of Chicago |
Chimeric antigen receptors recognizing cancer-spevific tn glycopeptide variants
|
|
KR102375998B1
(ko)
|
2014-02-14 |
2022-03-21 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
키메라 항원 수용체 및 제조방법
|
|
CN103820393B
(zh)
*
|
2014-02-24 |
2016-09-07 |
西比曼生物科技(上海)有限公司 |
工程化cd20靶向性的nkt细胞及其制备方法和应用
|
|
PL3888674T3
(pl)
|
2014-04-07 |
2024-09-23 |
Novartis Ag |
Leczenie nowotworu złośliwego z zastosowaniem chimerycznego receptora antygenowego anty-CD19
|
|
KR102463529B1
(ko)
|
2014-04-10 |
2022-11-07 |
시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 |
약물 관련 트랜스진 발현
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
BR112017000939A2
(pt)
|
2014-07-21 |
2017-11-14 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico de cll-1
|
|
EP3722316A1
(en)
|
2014-07-21 |
2020-10-14 |
Novartis AG |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置
|
|
ES2715413T3
(es)
*
|
2014-07-29 |
2019-06-04 |
Cellectis |
Receptores de antígeno quiméricos específicos para ROR1 (NTRKR1) para inmunoterapia contra el cáncer
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
WO2016033488A1
(en)
|
2014-08-29 |
2016-03-03 |
Board Of Regents, The University Of Texas System |
Administration of kynurenine depleting enzymes for tumor therapy
|
|
JP6810685B2
(ja)
|
2014-09-04 |
2021-01-06 |
セレクティスCellectis |
癌免疫療法のための栄養膜糖タンパク質(5t4、tpbg)特異的キメラ抗原受容体
|
|
EP3193933B1
(en)
|
2014-09-17 |
2021-04-28 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Anti-cd276 antibodies (b7h3)
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
CN114107424A
(zh)
|
2014-10-08 |
2022-03-01 |
诺华股份有限公司 |
预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
|
|
EA201700181A1
(ru)
|
2014-10-14 |
2017-09-29 |
Галозим, Инк. |
Композиции аденозиндеаминазы-2 (ада-2), их варианты и способы использования
|
|
US10570186B2
(en)
|
2014-11-05 |
2020-02-25 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors (CAR) to selectively target protein complexes
|
|
EP3215535A2
(en)
*
|
2014-11-05 |
2017-09-13 |
Board of Regents, The University of Texas System |
Gene modified immune effector cells and engineered cells for expansion of immune effector cells
|
|
WO2016076345A1
(ja)
|
2014-11-11 |
2016-05-19 |
中外製薬株式会社 |
改変された抗体可変領域を含む抗原結合分子のライブラリ
|
|
KR20250067192A
(ko)
|
2014-12-03 |
2025-05-14 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 치료를 위한 방법 및 조성물
|
|
ES2921208T3
(es)
*
|
2014-12-08 |
2022-08-19 |
Us Health |
Receptores de antígeno quimérico anti-CD70
|
|
CA3224507A1
(en)
|
2014-12-24 |
2016-06-30 |
Autolus Limited |
Cell co-expressing chimeric antigen receptors binding cd19 and cd22
|
|
IL253149B2
(en)
|
2014-12-29 |
2023-11-01 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
|
JP6912386B2
(ja)
|
2015-01-26 |
2021-08-04 |
ザ ユニバーシティー オブ シカゴ |
癌特異的なIL13Rα2を認識するCAR T細胞
|
|
CN107683289B
(zh)
|
2015-01-26 |
2021-08-06 |
芝加哥大学 |
IL13Rα2结合剂和其在癌症治疗中的用途
|
|
KR102329836B1
(ko)
|
2015-01-26 |
2021-11-19 |
셀렉티스 |
암 면역치료를 위한 항-CLL1 특이적 단일-체인 키메라 항원 수용체들(scCARS)
|
|
WO2016123578A1
(en)
|
2015-01-30 |
2016-08-04 |
The Regents Of The University Of California |
Protein delivery in primary hematopoietic cells
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
AU2016219511B2
(en)
|
2015-02-09 |
2020-11-12 |
Research Development Foundation |
Engineered immunoglobulin Fc polypeptides displaying improved complement activation
|
|
WO2016149578A1
(en)
|
2015-03-19 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Dual specific anti-cd22-anti-cd19 chimeric antigen receptors
|
|
PT3271389T
(pt)
|
2015-03-20 |
2020-05-13 |
Us Health |
Anticorpos neutralizantes dirigidos contra a gp120 e sua utilização
|
|
JP6961490B2
(ja)
*
|
2015-04-08 |
2021-11-05 |
ノバルティス アーゲー |
Cd20療法、cd22療法、およびcd19キメラ抗原受容体(car)発現細胞との併用療法
|
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
GB201507111D0
(en)
*
|
2015-04-27 |
2015-06-10 |
Ucl Business Plc |
Nucleic acid construct
|
|
EP4424326A3
(en)
|
2015-06-10 |
2024-11-13 |
ImmunityBio, Inc. |
Modified nk-92 cells for treating cancer
|
|
FI3909972T3
(fi)
|
2015-06-19 |
2024-05-03 |
Sebastian Kobold |
Pd1-cd28-fuusioproteiineja ja niiden käyttö lääkkeessä
|
|
DK3313874T3
(da)
|
2015-06-26 |
2021-05-03 |
Univ Southern California |
Maskering af kimære antigen-receptor t-celler til tumorspecifik aktivering
|
|
AR105433A1
(es)
|
2015-07-21 |
2017-10-04 |
Novartis Ag |
Métodos para mejorar la eficacia y expansión de las células inmunes
|
|
EP3331913A1
(en)
|
2015-08-07 |
2018-06-13 |
Novartis AG |
Treatment of cancer using chimeric cd3 receptor proteins
|
|
WO2017035251A1
(en)
|
2015-08-25 |
2017-03-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cells modified to overexpress c-myb
|
|
WO2017040380A2
(en)
|
2015-08-28 |
2017-03-09 |
Research Development Foundation |
Engineered antibody fc variants
|
|
WO2017040930A2
(en)
|
2015-09-03 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Biomarkers predictive of cytokine release syndrome
|
|
WO2017044699A1
(en)
*
|
2015-09-10 |
2017-03-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-cd276 chimeric antigen receptors
|
|
WO2017062748A1
(en)
|
2015-10-07 |
2017-04-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia
|
|
CA3001507C
(en)
|
2015-10-16 |
2023-09-19 |
Ludwig-Maximilians-Universitat Munchen |
Cxcr6-transduced t cells for targeted tumor therapy
|
|
WO2017070042A1
(en)
|
2015-10-20 |
2017-04-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing t cell populations using akt inhibitors
|
|
WO2017075147A1
(en)
|
2015-10-27 |
2017-05-04 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
HK1257295A1
(zh)
|
2015-12-04 |
2019-10-18 |
Novartis Ag |
用於免疫肿瘤学的组合物和方法
|
|
EP3393504B1
(en)
|
2015-12-22 |
2025-09-24 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
WO2017139199A1
(en)
|
2016-02-10 |
2017-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Inducible arginase
|
|
US11542486B2
(en)
|
2016-03-02 |
2023-01-03 |
Board Of Regents, The University Of Texas System |
Human kynureninase enzyme variants having improved pharmacological properties
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
JP7282521B2
(ja)
|
2016-04-08 |
2023-05-29 |
パーデュー・リサーチ・ファウンデイション |
Car t細胞療法のための方法および組成物
|
|
WO2017180587A2
(en)
|
2016-04-11 |
2017-10-19 |
Obsidian Therapeutics, Inc. |
Regulated biocircuit systems
|
|
CN107298715B
(zh)
*
|
2016-04-15 |
2021-05-04 |
阿思科力(苏州)生物科技有限公司 |
Slit2D2-嵌合抗原受体及其应用
|
|
CN105968210B
(zh)
*
|
2016-05-13 |
2019-05-31 |
深圳生创精准医疗科技有限公司 |
靶向cd22的强杀伤性嵌合抗原受体t细胞及其在制备治疗肿瘤的药物中的用途
|
|
CN106167527A
(zh)
*
|
2016-06-13 |
2016-11-30 |
长沙郝怡雅医药科技有限公司 |
一种融合蛋白
|
|
GB201610512D0
(en)
*
|
2016-06-16 |
2016-08-03 |
Autolus Ltd |
Chimeric antigen receptor
|
|
CN109476749A
(zh)
|
2016-06-30 |
2019-03-15 |
豪夫迈·罗氏有限公司 |
改良的过继性t细胞疗法
|
|
CA3037518A1
(en)
|
2016-09-21 |
2018-03-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (car) that targets chemokine receptor ccr4 and its use
|
|
WO2018057447A1
(en)
|
2016-09-23 |
2018-03-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of preparing an isolated population of dendritic cells and methods of treating cancer using same
|
|
AU2017336094A1
(en)
|
2016-09-29 |
2019-04-18 |
Immunitybio, Inc. |
HLA class I-deficient NK-92 cells with decreased immunogenicity
|
|
WO2018067992A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
MA46649A
(fr)
|
2016-10-13 |
2019-08-21 |
Juno Therapeutics Inc |
Méthodes et compositions d'immunothérapie impliquant des modulateurs de la voie métabolique du tryptophane
|
|
EP4092049A1
(en)
|
2016-10-20 |
2022-11-23 |
Celgene Corporation |
Cereblon-based heterodimerizable chimeric antigen receptors
|
|
CN107964549B
(zh)
*
|
2016-10-20 |
2020-12-08 |
上海恒润达生生物科技有限公司 |
靶向cd22的嵌合抗原受体及其用途
|
|
EP3555266B1
(en)
|
2016-12-13 |
2023-11-15 |
The United States of America, as Represented by The Secretary, Department of Health and Human Services |
Methods of preparing an isolated or purified population of thymic emigrant cells and methods of treatment using same
|
|
IL267543B2
(en)
|
2017-01-06 |
2024-07-01 |
Immunitybio Inc |
Modified nk-92 cells and compositions thereof for use in the treatment of cancer and methods of preparation thereof
|
|
ES2880010T3
(es)
*
|
2017-01-09 |
2021-11-23 |
Lentigen Tech Inc |
Composiciones y métodos para tratar el cáncer con inmunoterapia antimesotelina
|
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
|
CN110612119B
(zh)
|
2017-02-07 |
2024-10-29 |
西雅图儿童医院(Dba西雅图儿童研究所) |
磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂
|
|
BR112019017628A2
(pt)
|
2017-02-24 |
2020-07-07 |
Macrogenics, Inc. |
molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição
|
|
US11850262B2
(en)
|
2017-02-28 |
2023-12-26 |
Purdue Research Foundation |
Compositions and methods for CAR T cell therapy
|
|
SG10202001869VA
(en)
*
|
2017-03-03 |
2020-04-29 |
Obsidian Therapeutics Inc |
Cd19 compositions and methods for immunotherapy
|
|
US11629340B2
(en)
|
2017-03-03 |
2023-04-18 |
Obsidian Therapeutics, Inc. |
DHFR tunable protein regulation
|
|
EP3601561A2
(en)
|
2017-03-22 |
2020-02-05 |
Novartis AG |
Compositions and methods for immunooncology
|
|
SG11201908659RA
(en)
*
|
2017-03-27 |
2019-10-30 |
Noile Immune Biotech Inc |
Chimeric antigen receptor
|
|
PT3592379T
(pt)
|
2017-03-31 |
2024-05-31 |
Cellectis Sa |
Células imunitárias manipuladas universais dotadas de recetor antigénico quimérico anti-cd22
|
|
AU2018243664B2
(en)
|
2017-03-31 |
2024-02-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of treating T cell exhaustion by inhibiting or modulating T cell receptor signaling
|
|
WO2018189360A1
(en)
|
2017-04-13 |
2018-10-18 |
Cellectis |
New sequence specific reagents targeting ccr5 in primary hematopoietic cells
|
|
CN110753555A
(zh)
|
2017-04-19 |
2020-02-04 |
得克萨斯州大学系统董事会 |
表达工程化抗原受体的免疫细胞
|
|
CN110650975B
(zh)
|
2017-05-15 |
2024-04-05 |
美国卫生和人力服务部 |
双顺反子嵌合抗原受体及其用途
|
|
EP3630980B1
(en)
*
|
2017-06-01 |
2023-11-01 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cell preparation and uses thereof
|
|
US12384830B2
(en)
|
2017-06-02 |
2025-08-12 |
Regents Of The University Of Minnesota |
Compositions and methods for improving immunotherapy
|
|
EP3635098B1
(en)
|
2017-06-05 |
2021-09-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T-cells modified to overexpress phf19
|
|
JP2020524992A
(ja)
*
|
2017-06-22 |
2020-08-27 |
ユニバーシティ オブ サザン カリフォルニア |
キメラ抗原受容体操作ナチュラルキラー細胞を化学療法薬物担体として使用する組み合わせがん療法
|
|
EP3645036A1
(en)
|
2017-06-30 |
2020-05-06 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
US11235004B2
(en)
|
2017-06-30 |
2022-02-01 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Lymphocyte cell lines and uses thereof
|
|
CA3076337A1
(en)
|
2017-09-19 |
2019-03-28 |
Massachusetts Institute Of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
|
US20200316122A1
(en)
|
2017-10-11 |
2020-10-08 |
The United States Of America,As Represented By The Secretary,Department Of Health And Human Services |
Methods of producing t cell populations using p38 mapk inhibitors
|
|
JP7275118B2
(ja)
*
|
2017-10-16 |
2023-05-17 |
レンティジェン・テクノロジー・インコーポレイテッド |
抗cd22免疫療法によってがんを処置するための組成物および方法
|
|
CA3079264A1
(en)
*
|
2017-10-18 |
2019-04-25 |
Intrexon Corporation |
Polypeptide compositions comprising spacers
|
|
KR20200086278A
(ko)
|
2017-10-18 |
2020-07-16 |
노파르티스 아게 |
선택적 단백질 분해를 위한 조성물 및 방법
|
|
WO2019084284A1
(en)
|
2017-10-27 |
2019-05-02 |
Coneksis, Inc. |
NK CELLS FOR USE IN THE TREATMENT OF CANCER IN DOGS
|
|
JP7357616B2
(ja)
|
2017-12-05 |
2023-10-06 |
中外製薬株式会社 |
Cd3およびcd137に結合する改変された抗体可変領域を含む抗原結合分子
|
|
WO2019117976A1
(en)
|
2017-12-17 |
2019-06-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Peptide hydrogels and use thereof
|
|
BR112020014913A2
(pt)
|
2018-01-22 |
2020-12-08 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Métodos para uso de células t car
|
|
US20210040451A1
(en)
|
2018-01-31 |
2021-02-11 |
Nantkwest, Inc. |
Use of 5% human albumin in wash and harvest media
|
|
SG11202007426XA
(en)
|
2018-02-06 |
2020-09-29 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
|
EP3749770B9
(en)
|
2018-02-09 |
2025-12-17 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Tethered interleukin-15 and interleukin-21
|
|
KR102828999B1
(ko)
|
2018-02-11 |
2025-07-04 |
메모리얼 슬로안 케터링 캔서 센터 |
비-hla 제한된 t 세포 수용체 및 이의 용도
|
|
CN111918661A
(zh)
|
2018-02-21 |
2020-11-10 |
得克萨斯大学体系董事会 |
用于活化和扩增自然杀伤细胞的方法及其用途
|
|
CA3091674A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
US10780120B2
(en)
*
|
2018-03-06 |
2020-09-22 |
The Trustees Of The University Of Pennsylvania |
Prostate-specific membrane antigen cars and methods of use thereof
|
|
WO2019177986A1
(en)
|
2018-03-12 |
2019-09-19 |
Nantkwest, Inc. |
Use of cd33car modified high affinity nk cells (t-hank) to reduce myeloid-derived suppressor cells suppressor activity (or reduce negative impact on nk cell activity)
|
|
JOP20200259A1
(ar)
*
|
2018-04-10 |
2020-10-11 |
Kite Pharma Inc |
مستقبلات خيمرية لـ dll3 وطرق استخدامها
|
|
CN112292400A
(zh)
|
2018-04-13 |
2021-01-29 |
桑格摩生物治疗法国公司 |
对白介素-23受体特异的嵌合抗原受体
|
|
SG11202009559RA
(en)
|
2018-04-16 |
2020-10-29 |
Univ Texas |
Human kynureninase enzymes and uses thereof
|
|
US12415845B2
(en)
|
2018-04-24 |
2025-09-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T cell populations using hydroxycitric acid and/or a salt thereof
|
|
IL321548A
(en)
*
|
2018-05-22 |
2025-08-01 |
Immunitybio Inc |
Recombinant NK cells expressing a chimeric antigen receptor (CAR) for epsilon-FC and uses thereof
|
|
US20210198628A1
(en)
|
2018-05-22 |
2021-07-01 |
Nantkwest, Inc. |
Basal media for growing nk-92 cells
|
|
WO2019226649A1
(en)
|
2018-05-22 |
2019-11-28 |
Nantkwest, Inc. |
Optimization of nk-92 cell growth using poloxamer
|
|
TWI890660B
(zh)
|
2018-06-13 |
2025-07-21 |
瑞士商諾華公司 |
Bcma 嵌合抗原受體及其用途
|
|
US20210267190A1
(en)
|
2018-07-10 |
2021-09-02 |
Nantkwest, Inc. |
Cryopreservation
|
|
CN112424343B
(zh)
|
2018-07-10 |
2024-10-22 |
免疫生物公司 |
从脐带血产生cik nkt细胞
|
|
AU2019301675B2
(en)
*
|
2018-07-12 |
2025-09-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Affinity matured CD22-specific monoclonal antibody and uses thereof
|
|
US12498363B2
(en)
|
2018-08-01 |
2025-12-16 |
Immunitybio, Inc. |
Combined invasion and cytotoxicity assay using chemokine secreting target cells
|
|
AU2018434924A1
(en)
|
2018-08-01 |
2021-01-28 |
Immunitybio, Inc. |
Chemokine responsive activated natural killer cells with secondary homing activation for verified targets
|
|
IL296050B2
(en)
|
2018-08-01 |
2024-12-01 |
Immunitybio Inc |
A quadricistronic system comprising a homing receptor or a cytokine, and chimeric antigen receptor for genetic modification of immunotherapies
|
|
CN113286824A
(zh)
|
2018-08-03 |
2021-08-20 |
中外制药株式会社 |
包含两个彼此连接的抗原结合结构域的抗原结合分子
|
|
CN109022363A
(zh)
*
|
2018-08-15 |
2018-12-18 |
马晓冬 |
一种基于PiggyBac载体的CD-133-CAR-T系统构建方法
|
|
CA3113618A1
(en)
|
2018-09-28 |
2020-04-02 |
Massachusetts Institute Of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
KR102775767B1
(ko)
|
2018-10-22 |
2025-03-07 |
상하이 젠베이스 바이오테크놀로지 씨오., 엘티디. |
항-cldn18.2 항체 및 이의 용도
|
|
WO2020096646A1
(en)
|
2018-11-06 |
2020-05-14 |
Nantkwest, Inc. |
Chimeric antigen receptor-modified nk-92 cells
|
|
US12109238B2
(en)
|
2018-11-06 |
2024-10-08 |
Immunitybio, Inc. |
Chimeric antigen receptor-modified NK-92 cells
|
|
WO2020112669A1
(en)
|
2018-11-26 |
2020-06-04 |
Nantkwest, Inc. |
Il-2 dependent nk-92 cells with stable fc receptor expression
|
|
EP3670530A1
(en)
|
2018-12-18 |
2020-06-24 |
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft |
Cd22-specific t cell receptors and adoptive t cell therapy for treatment of b cell malignancies
|
|
EP3935151A1
(en)
|
2019-03-08 |
2022-01-12 |
Klinikum der Universität München |
Ccr8 expressing lymphocytes for targeted tumor therapy
|
|
WO2020264019A1
(en)
|
2019-06-24 |
2020-12-30 |
Children's Hospital Los Angeles |
Bcl11b overexpression to enhance human thymopoiesis and t cell function
|
|
EP3990491A1
(en)
|
2019-06-26 |
2022-05-04 |
Massachusetts Institute of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
JP2022539589A
(ja)
|
2019-07-02 |
2022-09-12 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
EGFRvIIIと結合するモノクローナル抗体およびその使用
|
|
AU2020315213A1
(en)
*
|
2019-07-17 |
2022-02-03 |
National University Of Singapore |
Functional binders synthesized and secreted by immune cells
|
|
EP4007809A4
(en)
|
2019-08-01 |
2023-02-22 |
ImmunityBio, Inc. |
NK-92 CELLS MODIFIED BY CHIMERIC ANTI-B7-H4 ANTIGEN RECEPTOR
|
|
JP7692897B2
(ja)
|
2019-09-10 |
2025-06-16 |
オブシディアン セラピューティクス, インコーポレイテッド |
調節可能な制御のためのca2-il15融合タンパク質
|
|
WO2021051390A1
(zh)
|
2019-09-20 |
2021-03-25 |
上海吉倍生物技术有限公司 |
靶向bcma的抗体及嵌合抗原受体
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
AR120566A1
(es)
|
2019-11-26 |
2022-02-23 |
Novartis Ag |
Receptores de antígeno quiméricos y sus usos
|
|
BR112022009679A2
(pt)
|
2019-11-26 |
2022-08-09 |
Novartis Ag |
Receptores de antígeno quimérico cd19 e cd22 e usos dos mesmos
|
|
US11230699B2
(en)
|
2020-01-28 |
2022-01-25 |
Immunitybio, Inc. |
Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors
|
|
JP2023517889A
(ja)
|
2020-03-10 |
2023-04-27 |
マサチューセッツ インスティテュート オブ テクノロジー |
NPM1c陽性がんの免疫療法のための組成物および方法
|
|
IL296242A
(en)
|
2020-03-10 |
2022-11-01 |
Massachusetts Inst Technology |
Methods for producing engineered memory-like nk cells and preparations containing them
|
|
CA3173587A1
(en)
|
2020-03-31 |
2021-10-07 |
Chugai Seiyaku Kabushiki-Kaisha |
Dll3-targeting multispecific antigen-binding molecules and uses thereof
|
|
US12448453B2
(en)
*
|
2020-04-02 |
2025-10-21 |
Nanjing IASO Biotechnology Co., Ltd. |
Fully human anti-human CD22 chimeric antigen receptor and application thereof
|
|
CN111484562B
(zh)
*
|
2020-04-25 |
2021-08-20 |
首都医科大学附属北京朝阳医院 |
一种靶向cd22蛋白的抗体、嵌合抗原受体和药物
|
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
|
IL298558A
(en)
|
2020-05-27 |
2023-01-01 |
Antion Biosciences Sa |
Adapter molecules to re-direct car t cells to an antigen of interest
|
|
CA3191211A1
(en)
|
2020-09-08 |
2022-03-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell phenotypes associated with response to adoptive cell therapy
|
|
EP4243937A2
(en)
|
2020-11-13 |
2023-09-20 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Enhanced antigen reactivity of immune cells expressing a mutant non-signaling cd3 zeta chain
|
|
AU2021386370A1
(en)
|
2020-11-24 |
2023-06-22 |
Lyell Immunopharma, Inc. |
Methods for making, compositions comprising, and methods of using rejuvenated t cells
|
|
TW202237827A
(zh)
|
2020-12-03 |
2022-10-01 |
美商世紀治療股份有限公司 |
經基因工程改造之細胞及其用途
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
WO2022133169A1
(en)
|
2020-12-18 |
2022-06-23 |
Century Therapeutics, Inc. |
Chimeric antigen receptor systems with adaptable receptor specificity
|
|
CA3212530A1
(en)
|
2021-03-05 |
2022-09-09 |
Shanghai GenBase Biotechnology Co., Ltd. |
Anti-cldn6 antibody and use thereof
|
|
US20240269182A1
(en)
*
|
2021-05-27 |
2024-08-15 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Modified Chimeric Antigen Receptor and Use thereof
|
|
WO2023021113A1
(en)
|
2021-08-18 |
2023-02-23 |
Julius-Maximilians-Universität Würzburg |
Hybrid tumor/cancer therapy based on targeting the resolution of or inducing transcription-replication conflicts (trcs)
|
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
CA3241588A1
(en)
|
2021-12-31 |
2023-07-06 |
Sri Krishna |
T cell therapy with vaccination as a combination immunotherapy against cancer
|
|
TW202340474A
(zh)
|
2022-01-11 |
2023-10-16 |
大陸商深圳市珈鈺生物科技有限公司 |
樹突細胞腫瘤疫苗和其用途
|
|
CN114774364B
(zh)
*
|
2022-04-26 |
2024-04-26 |
深圳市体内生物医药科技有限公司 |
一种嵌合抗原受体t细胞及其制备方法和应用
|
|
AU2023283773A1
(en)
|
2022-06-10 |
2024-12-19 |
Research Development Foundation |
Engineered fcriib selective igg1 fc variants and uses thereof
|
|
CN118359729A
(zh)
*
|
2023-01-19 |
2024-07-19 |
武汉昭智生物技术有限公司 |
一种car分子、包含其的细胞或外泌体及它们的应用
|
|
WO2025014896A1
(en)
|
2023-07-07 |
2025-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Humanized 40h3 antibody
|
|
WO2025160480A1
(en)
|
2024-01-26 |
2025-07-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Enhanced tumor reactivity of t cells lacking sit1, lax1, or trat1
|
|
WO2025250587A1
(en)
|
2024-05-29 |
2025-12-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Drug-regulatable, inducible cytokine expression
|