JP2014526468A5 - - Google Patents

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JP2014526468A5
JP2014526468A5 JP2014529902A JP2014529902A JP2014526468A5 JP 2014526468 A5 JP2014526468 A5 JP 2014526468A5 JP 2014529902 A JP2014529902 A JP 2014529902A JP 2014529902 A JP2014529902 A JP 2014529902A JP 2014526468 A5 JP2014526468 A5 JP 2014526468A5
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JP
Japan
Prior art keywords
pneumonia
ceftrozan
pharmaceutical composition
nosocomial
administering
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JP2014529902A
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JP2014526468A (ja
JP6151257B2 (ja
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Priority claimed from PCT/US2012/054191 external-priority patent/WO2013036783A2/en
Publication of JP2014526468A publication Critical patent/JP2014526468A/ja
Publication of JP2014526468A5 publication Critical patent/JP2014526468A5/ja
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Publication of JP6151257B2 publication Critical patent/JP6151257B2/ja
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Claims (10)

  1. gのセフトロザン及び1gのタゾバクタムを含む医薬組成物を静脈内投与する工程を含む、ヒトのを治療する方法。
  2. 前記医薬組成物が8時間毎に約1回投与される、請求項1に記載の方法。
  3. gのセフトロザンを含む医薬組成物を8時間毎に約1回静脈内投与する工程を含む、ヒトのを治療する方法。
  4. 更にタゾバクタムを前記ヒトに投与する工程を含む、請求項に記載の方法。
  5. 前記セフトロザンが遊離塩基の形態である、請求項1〜4のいずれか一項に記載の方法。
  6. 前記セフトロザンが塩の形態である、請求項1〜4のいずれか一項に記載の方法。
  7. 前記セフトロザンの塩がセフトロザン硫酸水素塩である、請求項6記載の方法。
  8. 前記肺炎が院内肺炎である、請求項1〜7のいずれか一項に記載の方法。
  9. 前記院内肺炎が院内感染性肺炎である、請求項8に記載の方法。
  10. 前記肺炎が人工呼吸器関連肺炎である、請求項1〜9のいずれか一項に記載の方法。
JP2014529902A 2011-09-09 2012-09-07 肺内感染症の治療方法 Active JP6151257B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161532914P 2011-09-09 2011-09-09
US61/532,914 2011-09-09
US201261657386P 2012-06-08 2012-06-08
US61/657,386 2012-06-08
PCT/US2012/054191 WO2013036783A2 (en) 2011-09-09 2012-09-07 Methods for treating intrapulmonary infections

Publications (3)

Publication Number Publication Date
JP2014526468A JP2014526468A (ja) 2014-10-06
JP2014526468A5 true JP2014526468A5 (ja) 2015-10-29
JP6151257B2 JP6151257B2 (ja) 2017-06-21

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ID=47830390

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014529902A Active JP6151257B2 (ja) 2011-09-09 2012-09-07 肺内感染症の治療方法

Country Status (9)

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US (5) US20130065874A1 (ja)
EP (3) EP2753326A4 (ja)
JP (1) JP6151257B2 (ja)
CN (1) CN103945842A (ja)
CA (1) CA2848012A1 (ja)
EA (1) EA028342B1 (ja)
HK (1) HK1200096A1 (ja)
MX (1) MX352760B (ja)
WO (1) WO2013036783A2 (ja)

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GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
JP6151257B2 (ja) 2011-09-09 2017-06-21 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 肺内感染症の治療方法
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US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
EP3100732A1 (en) * 2013-03-15 2016-12-07 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274993A1 (en) * 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
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WO2015196077A1 (en) * 2014-06-20 2015-12-23 Merck Sharp & Dohme Corp. Reactions of thiadiazolyl-oximinoacetic acid derivative compounds
WO2016028670A1 (en) * 2014-08-18 2016-02-25 Merck Sharp & Dohme Corp. Salt forms of ceftolozane
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