JP2014218523A5 - - Google Patents
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- Publication number
- JP2014218523A5 JP2014218523A5 JP2014167814A JP2014167814A JP2014218523A5 JP 2014218523 A5 JP2014218523 A5 JP 2014218523A5 JP 2014167814 A JP2014167814 A JP 2014167814A JP 2014167814 A JP2014167814 A JP 2014167814A JP 2014218523 A5 JP2014218523 A5 JP 2014218523A5
- Authority
- JP
- Japan
- Prior art keywords
- orally disintegrating
- disintegrating tablet
- tablet according
- outer shell
- mass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000006191 orally-disintegrating tablet Substances 0.000 claims 16
- RYYCJUAHISIHTL-UHFFFAOYSA-N 5-azaorotic acid Chemical compound OC(=O)C1=NC(=O)NC(=O)N1 RYYCJUAHISIHTL-UHFFFAOYSA-N 0.000 claims 4
- ZPLQIPFOCGIIHV-UHFFFAOYSA-N Gimeracil Chemical compound OC1=CC(=O)C(Cl)=CN1 ZPLQIPFOCGIIHV-UHFFFAOYSA-N 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 4
- 229950009822 gimeracil Drugs 0.000 claims 4
- 229950000193 oteracil Drugs 0.000 claims 4
- 239000003826 tablet Substances 0.000 claims 4
- WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 claims 4
- 229960001674 tegafur Drugs 0.000 claims 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 3
- 229920000881 Modified starch Polymers 0.000 claims 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 3
- 229960000913 crospovidone Drugs 0.000 claims 3
- 239000007884 disintegrant Substances 0.000 claims 3
- 239000008101 lactose Substances 0.000 claims 3
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 3
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 3
- 229920002678 cellulose Polymers 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 239000008358 core component Substances 0.000 claims 2
- 230000001186 cumulative effect Effects 0.000 claims 2
- 238000010998 test method Methods 0.000 claims 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920002261 Corn starch Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 229950008138 carmellose Drugs 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 229940099112 cornstarch Drugs 0.000 claims 1
- 238000012812 general test Methods 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000012360 testing method Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014167814A JP5769853B2 (ja) | 2011-05-25 | 2014-08-20 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011116884 | 2011-05-25 | ||
| JP2011116884 | 2011-05-25 | ||
| JP2014167814A JP5769853B2 (ja) | 2011-05-25 | 2014-08-20 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516428A Division JP5689173B2 (ja) | 2011-05-25 | 2012-05-24 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014218523A JP2014218523A (ja) | 2014-11-20 |
| JP2014218523A5 true JP2014218523A5 (enExample) | 2015-04-09 |
| JP5769853B2 JP5769853B2 (ja) | 2015-08-26 |
Family
ID=47217314
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516428A Active JP5689173B2 (ja) | 2011-05-25 | 2012-05-24 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
| JP2014167814A Active JP5769853B2 (ja) | 2011-05-25 | 2014-08-20 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516428A Active JP5689173B2 (ja) | 2011-05-25 | 2012-05-24 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20140335174A1 (enExample) |
| EP (1) | EP2716290B1 (enExample) |
| JP (2) | JP5689173B2 (enExample) |
| KR (2) | KR101869127B1 (enExample) |
| AU (1) | AU2012259803B2 (enExample) |
| BR (1) | BR112013030093B1 (enExample) |
| CA (1) | CA2836865C (enExample) |
| ES (1) | ES2671926T3 (enExample) |
| IL (1) | IL229372B (enExample) |
| MX (1) | MX353289B (enExample) |
| MY (1) | MY167883A (enExample) |
| PH (1) | PH12013502323A1 (enExample) |
| RU (1) | RU2601620C2 (enExample) |
| SG (2) | SG194922A1 (enExample) |
| TW (2) | TWI488659B (enExample) |
| WO (1) | WO2012161240A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013030093B1 (pt) * | 2011-05-25 | 2019-12-10 | Taiho Pharmaceutical Co Ltd | comprimido revestido seco de desintegração oral contendo tegafur, gimeracilo e oteracilo potássico |
| CN107837273A (zh) * | 2016-09-18 | 2018-03-27 | 江苏金甙生物技术有限公司 | 一种肠溶替吉奥缓释制剂及其制备方法 |
| CN107865871B (zh) * | 2016-09-23 | 2021-09-03 | 江苏恒瑞医药股份有限公司 | 一种替吉奥组合物及其制备方法 |
| CN106619689B (zh) * | 2016-12-30 | 2018-05-01 | 陈晓华 | 一种用于治疗癌症的药物组合物、试剂盒及其应用 |
| US20220408745A1 (en) * | 2019-09-13 | 2022-12-29 | Meiji Co., Ltd. | Solid food and solid milk having hole penetrating first face and second face |
| CN119365195A (zh) * | 2022-06-10 | 2025-01-24 | 大鹏药品工业株式会社 | 含有匹米替比的医药组合物 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0148589B1 (ko) * | 1991-05-27 | 1998-11-02 | 고바야시 유끼오 | 항종양 효과의 상승 및 종양의 치료를 위한 조성물 및 키트 |
| DE69901938T3 (de) * | 1998-03-06 | 2012-08-02 | Aptalis Pharma S.R.L. | Schnell zerfallende tablette |
| ES2257412T3 (es) * | 2000-05-18 | 2006-08-01 | Therics, Inc. | Encapsulacion de un nucleo toxico en una region no toxica en una forma de dosificacion oral. |
| CN1284532C (zh) * | 2001-09-28 | 2006-11-15 | 株式会社三和化学研究所 | 有核型速溶崩解性成型品 |
| DK1443917T3 (da) * | 2001-11-07 | 2006-07-17 | Synthon Bv | Tamsulosintabletter |
| US6723348B2 (en) * | 2001-11-16 | 2004-04-20 | Ethypharm | Orodispersible tablets containing fexofenadine |
| US20030215502A1 (en) * | 2002-03-20 | 2003-11-20 | Elan Pharma International Limited | Fast dissolving dosage forms having reduced friability |
| MXPA05009781A (es) * | 2003-03-14 | 2005-10-26 | Taiho Pharmaceutical Co Ltd | Potenciador de efecto antitumoral y agente antitumoral. |
| EP1680092A2 (en) * | 2003-09-29 | 2006-07-19 | Cipla Ltd. | Pharmaceutical formulation with improved stability |
| CN100333726C (zh) | 2004-12-23 | 2007-08-29 | 鲁南制药集团股份有限公司 | 含有替加氟、吉莫斯特和氧嗪酸钾的口腔崩解片 |
| EP1864683B1 (en) * | 2005-04-01 | 2010-09-01 | Taiho Pharmaceutical Co., Ltd. | Radiotherapy enhancer |
| JP4994618B2 (ja) * | 2005-08-11 | 2012-08-08 | 学校法人北里研究所 | Ｔｓ−１／カンプトテシン類による化学放射線療法 |
| CN101909602B (zh) * | 2007-12-27 | 2012-06-13 | 大鹏药品工业株式会社 | 口服粉粒状抗肿瘤剂 |
| TWI468188B (zh) * | 2008-01-30 | 2015-01-11 | Univ Tokushima | Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation |
| KR100934876B1 (ko) | 2008-01-31 | 2010-01-06 | 성균관대학교산학협력단 | Ｌｉｇａ공정의 도금방법 |
| CN101380327B (zh) * | 2008-10-09 | 2011-01-26 | 北京恒瑞康达医药科技发展有限公司 | 抗癌复合缓释组合物及制备 |
| JP5553522B2 (ja) | 2009-03-31 | 2014-07-16 | 大鵬薬品工業株式会社 | 経口投与用医薬組成物 |
| JPWO2010131460A1 (ja) * | 2009-05-12 | 2012-11-01 | 大鵬薬品工業株式会社 | テガフール・ギメラシル・オテラシルカリウム配合剤及びオキサリプラチンを含有する抗腫瘍剤 |
| CN101711765B (zh) * | 2009-10-31 | 2011-03-23 | 山东新时代药业有限公司 | 一种含有替加氟、吉美嘧啶和奥替拉西钾的分散片 |
| BR112013030093B1 (pt) * | 2011-05-25 | 2019-12-10 | Taiho Pharmaceutical Co Ltd | comprimido revestido seco de desintegração oral contendo tegafur, gimeracilo e oteracilo potássico |
| CN102614183B (zh) * | 2012-03-05 | 2013-10-30 | 齐鲁制药(海南)有限公司 | 一种替吉奥的口服制剂 |
-
2012
- 2012-05-24 BR BR112013030093A patent/BR112013030093B1/pt not_active IP Right Cessation
- 2012-05-24 CA CA2836865A patent/CA2836865C/en not_active Expired - Fee Related
- 2012-05-24 KR KR1020137033946A patent/KR101869127B1/ko not_active Expired - Fee Related
- 2012-05-24 KR KR1020177016653A patent/KR20170072959A/ko not_active Ceased
- 2012-05-24 EP EP12789023.4A patent/EP2716290B1/en not_active Not-in-force
- 2012-05-24 US US14/118,952 patent/US20140335174A1/en not_active Abandoned
- 2012-05-24 SG SG2013083829A patent/SG194922A1/en unknown
- 2012-05-24 JP JP2013516428A patent/JP5689173B2/ja active Active
- 2012-05-24 ES ES12789023.4T patent/ES2671926T3/es active Active
- 2012-05-24 MX MX2013013563A patent/MX353289B/es active IP Right Grant
- 2012-05-24 WO PCT/JP2012/063260 patent/WO2012161240A1/ja not_active Ceased
- 2012-05-24 MY MYPI2013702158A patent/MY167883A/en unknown
- 2012-05-24 SG SG10201505503WA patent/SG10201505503WA/en unknown
- 2012-05-24 PH PH1/2013/502323A patent/PH12013502323A1/en unknown
- 2012-05-24 TW TW101118538A patent/TWI488659B/zh not_active IP Right Cessation
- 2012-05-24 AU AU2012259803A patent/AU2012259803B2/en not_active Ceased
- 2012-05-24 RU RU2013157528/15A patent/RU2601620C2/ru active
- 2012-05-24 TW TW104113084A patent/TWI566787B/zh not_active IP Right Cessation
-
2013
- 2013-11-11 IL IL229372A patent/IL229372B/en active IP Right Grant
-
2014
- 2014-08-20 JP JP2014167814A patent/JP5769853B2/ja active Active
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