JP2014167026A5 - - Google Patents
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- Publication number
- JP2014167026A5 JP2014167026A5 JP2014121055A JP2014121055A JP2014167026A5 JP 2014167026 A5 JP2014167026 A5 JP 2014167026A5 JP 2014121055 A JP2014121055 A JP 2014121055A JP 2014121055 A JP2014121055 A JP 2014121055A JP 2014167026 A5 JP2014167026 A5 JP 2014167026A5
- Authority
- JP
- Japan
- Prior art keywords
- sustained
- release preparation
- hydroxypropylmethylcellulose
- preparation according
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 16
- 239000003405 delayed action preparation Substances 0.000 claims 12
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 12
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 11
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 11
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 11
- 238000009472 formulation Methods 0.000 claims 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims 6
- -1 2-hydroxyethoxy Chemical group 0.000 claims 5
- 239000003349 gelling agent Substances 0.000 claims 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- URKOMYMAXPYINW-UHFFFAOYSA-N quetiapine Chemical compound C1CN(CCOCCO)CCN1C1=NC2=CC=CC=C2SC2=CC=CC=C12 URKOMYMAXPYINW-UHFFFAOYSA-N 0.000 claims 3
- 239000001509 sodium citrate Substances 0.000 claims 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- 239000008101 lactose Substances 0.000 claims 2
- 235000019359 magnesium stearate Nutrition 0.000 claims 2
- 239000008108 microcrystalline cellulose Substances 0.000 claims 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 2
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 2
- 239000003002 pH adjusting agent Substances 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 229940069328 povidone Drugs 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 208000028017 Psychotic disease Diseases 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 238000007906 compression Methods 0.000 claims 1
- 230000006835 compression Effects 0.000 claims 1
- UZVGSSNIUNSOFA-UHFFFAOYSA-N dibenzofuran-1-carboxylic acid Chemical compound O1C2=CC=CC=C2C2=C1C=CC=C2C(=O)O UZVGSSNIUNSOFA-UHFFFAOYSA-N 0.000 claims 1
- 239000011363 dried mixture Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 229960001375 lactose Drugs 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 229940057948 magnesium stearate Drugs 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 229960001790 sodium citrate Drugs 0.000 claims 1
- 235000011083 sodium citrates Nutrition 0.000 claims 1
- NYERMPLPURRVGM-UHFFFAOYSA-N thiazepine Chemical compound S1C=CC=CC=N1 NYERMPLPURRVGM-UHFFFAOYSA-N 0.000 claims 1
- 238000005550 wet granulation Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9611328.7 | 1996-05-31 | ||
| GBGB9611328.7A GB9611328D0 (en) | 1996-05-31 | 1996-05-31 | Pharmaceutical compositions |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011243832A Division JP5888549B2 (ja) | 1996-05-31 | 2011-11-07 | 医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014167026A JP2014167026A (ja) | 2014-09-11 |
| JP2014167026A5 true JP2014167026A5 (enExample) | 2014-10-23 |
Family
ID=10794541
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09541846A Pending JP2000511170A (ja) | 1996-05-31 | 1997-05-27 | 医薬組成物 |
| JP2006071695A Pending JP2006152006A (ja) | 1996-05-31 | 2006-03-15 | 医薬組成物 |
| JP2007030991A Pending JP2007119495A (ja) | 1996-05-31 | 2007-02-09 | 医薬組成物 |
| JP2011243832A Expired - Lifetime JP5888549B2 (ja) | 1996-05-31 | 2011-11-07 | 医薬組成物 |
| JP2014121055A Withdrawn JP2014167026A (ja) | 1996-05-31 | 2014-06-12 | 医薬組成物 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09541846A Pending JP2000511170A (ja) | 1996-05-31 | 1997-05-27 | 医薬組成物 |
| JP2006071695A Pending JP2006152006A (ja) | 1996-05-31 | 2006-03-15 | 医薬組成物 |
| JP2007030991A Pending JP2007119495A (ja) | 1996-05-31 | 2007-02-09 | 医薬組成物 |
| JP2011243832A Expired - Lifetime JP5888549B2 (ja) | 1996-05-31 | 2011-11-07 | 医薬組成物 |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP0907364B1 (enExample) |
| JP (5) | JP2000511170A (enExample) |
| CN (3) | CN1142780C (enExample) |
| AR (1) | AR003662A1 (enExample) |
| AT (1) | ATE222105T1 (enExample) |
| AU (1) | AU727219B2 (enExample) |
| BR (1) | BR9709271A (enExample) |
| CA (1) | CA2251944C (enExample) |
| CZ (1) | CZ293760B6 (enExample) |
| DE (1) | DE69714739T2 (enExample) |
| DK (1) | DK0907364T3 (enExample) |
| EG (1) | EG24118A (enExample) |
| ES (1) | ES2182079T3 (enExample) |
| GB (2) | GB9611328D0 (enExample) |
| HR (1) | HRP970299B1 (enExample) |
| HU (1) | HU225152B1 (enExample) |
| ID (1) | ID18352A (enExample) |
| IL (1) | IL127222A (enExample) |
| MY (1) | MY120120A (enExample) |
| NO (1) | NO327801B1 (enExample) |
| NZ (1) | NZ332198A (enExample) |
| PL (1) | PL189887B1 (enExample) |
| PT (1) | PT907364E (enExample) |
| RU (1) | RU2201754C2 (enExample) |
| SI (1) | SI0907364T1 (enExample) |
| SK (1) | SK284131B6 (enExample) |
| TR (1) | TR199802483T2 (enExample) |
| TW (1) | TW550076B (enExample) |
| UA (1) | UA50772C2 (enExample) |
| WO (1) | WO1997045124A1 (enExample) |
| ZA (1) | ZA974735B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9922271D0 (en) | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Formulation |
| SE0003126D0 (sv) * | 2000-09-05 | 2000-09-05 | Astrazeneca Ab | Method of treatment |
| BR0207297A (pt) | 2001-02-15 | 2005-04-19 | King Pharmaceuticals Inc | Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| SE0102855D0 (sv) * | 2001-08-27 | 2001-08-27 | Astrazeneca Ab | Method of treatment |
| JP3624954B1 (ja) | 2001-11-07 | 2005-03-02 | 藤沢薬品工業株式会社 | 分散不良薬物の溶出性を改善する方法 |
| TW200735878A (en) * | 2005-11-18 | 2007-10-01 | Astrazeneca Ab | Pharmaceutical compositions |
| US20100178333A1 (en) | 2006-01-25 | 2010-07-15 | Astron Research Limited | Sustained release dosage form of phenothiazine derivatives containing channelizer |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| GB0618879D0 (en) * | 2006-09-26 | 2006-11-01 | Zysis Ltd | Pharmaceutical compositions |
| PT103884A (pt) * | 2006-11-17 | 2008-05-19 | Astrazeneca Ab | Composições de libertação prolongada e métodos para a sua preparação |
| PT1958617E (pt) | 2007-02-14 | 2010-10-28 | Lesvi Laboratorios Sl | Composições farmacêuticas contendo fumarato de quetiapina |
| WO2008110337A2 (en) | 2007-03-09 | 2008-09-18 | Synthon B.V. | Pharmaceutical composition of quetiapine fumarate |
| EA018638B1 (ru) * | 2008-08-01 | 2013-09-30 | Крка, Товарна Здравил, Д. Д., Ново Место | Композиция кветиапина |
| EP2153834A3 (en) | 2008-08-07 | 2010-02-24 | Farmaprojects, S.A. | Extended release pharmaceutical compositions comprising quetiapine salts |
| DE102008046650A1 (de) | 2008-09-10 | 2010-03-11 | Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg | Quetiapin enthaltende Retardtablette |
| EP2373319B1 (en) * | 2009-01-05 | 2013-07-31 | Torrent Pharmaceuticals Limited | Sustained release pharmaceutical composition of quetiapine and process for preparation thereof |
| WO2010089259A2 (en) | 2009-02-04 | 2010-08-12 | Woerwag R&D Gmbh | Sustained release composition containing quetiapine |
| EP2233130A1 (en) * | 2009-03-23 | 2010-09-29 | Genepharm (Europe) Trading Limited | A sustained release oral composition of an antipsychotic agent |
| TWI478733B (zh) * | 2009-05-13 | 2015-04-01 | Wyeth Llc | 突釋藥物釋放組合物 |
| WO2011132008A2 (en) | 2010-04-22 | 2011-10-27 | EGIS Gyűgyszergyár Nyilvánosan Múködő Részvény társaság | Controlled release pharmaceutical composition |
| WO2011154118A1 (en) | 2010-06-07 | 2011-12-15 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Quetiapine prolonged-release tablets |
| DE102010033527A1 (de) | 2010-08-05 | 2012-02-09 | Acino Pharma Ag | Quetiapin-Tabletten |
| TR201008261A1 (tr) | 2010-10-08 | 2012-04-24 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Kontrollü salım gerçekleştiren ketiapin formülasyonları |
| CN102218042A (zh) * | 2011-05-26 | 2011-10-19 | 青岛黄海制药有限责任公司 | 富马酸喹硫平组合物的缓释片剂及其制备方法 |
| DE102011115690A1 (de) | 2011-10-11 | 2013-04-11 | Acino Pharma Ag | Quetiapin enthaltende Formulierungen |
| CN102406606B (zh) * | 2011-11-29 | 2013-01-23 | 海南美大制药有限公司 | 富马酸喹硫平脂质体固体制剂 |
| HRP20181758T1 (hr) | 2012-09-10 | 2018-12-28 | Pharmathen S.A. | Farmaceutski pripravak koji sadrži atipično antipsihotično sredstvo i postupak za njegovu pripravu |
| EP2848244A1 (en) | 2013-09-16 | 2015-03-18 | Yildiz Özsoy Erginer | Extended release tablet formulations of quetiapine |
| WO2016204939A1 (en) * | 2015-06-19 | 2016-12-22 | Biotie Therapies, Inc. | Controlled-release tozadenant formulations |
| CN106187873B (zh) * | 2016-07-25 | 2019-11-05 | 宜春学院 | 一种芳胺基烷基氧类化合物及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| US4775535A (en) * | 1986-04-04 | 1988-10-04 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4756911A (en) * | 1986-04-16 | 1988-07-12 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| DE3776269D1 (de) * | 1986-11-03 | 1992-03-05 | Schering Corp | Labetalol tablette mit verzoegerter wirkstoffabgabe. |
| IE59540B1 (en) * | 1987-01-09 | 1994-03-09 | Elan Corp | Sustained release capsule or tablet formulation |
| GB8705574D0 (en) * | 1987-03-10 | 1987-04-15 | Ici Plc | Preparation of thiazepine compound |
| US4983398A (en) * | 1987-12-21 | 1991-01-08 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
| IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Dispensing devices powered by hydrogel |
| SE9003902D0 (sv) * | 1990-12-07 | 1990-12-07 | Astra Ab | Solid dosage forms of a drug |
| IT1256651B (it) * | 1992-12-11 | 1995-12-12 | Giancarlo Santus | Composizione farmaceutica a rilascio controllato in sospensione liquida |
| JP3116970B2 (ja) * | 1991-06-12 | 2000-12-11 | 三菱東京製薬株式会社 | ペミロラストカリウムの徐放性製剤 |
| IT1256393B (it) * | 1992-11-17 | 1995-12-04 | Inverni Della Beffa Spa | Forme matriciali multistrato per il rilascio controllato di principi attivi |
| US5393765A (en) * | 1993-12-13 | 1995-02-28 | Hoffmann-La Roche Inc. | Pharmaceutical compositions with constant erosion volume for zero order controlled release |
| NZ287277A (en) * | 1994-05-13 | 1998-05-27 | Smithkline Beecham Corp | Oral preparation containing calcium source within a hydrophilic polymer matrix for increasing calcium absorption in the stomach |
-
1996
- 1996-05-31 GB GBGB9611328.7A patent/GB9611328D0/en active Pending
-
1997
- 1997-05-15 GB GBGB9709761.2A patent/GB9709761D0/en active Pending
- 1997-05-27 CZ CZ19983880A patent/CZ293760B6/cs not_active IP Right Cessation
- 1997-05-27 PT PT97924103T patent/PT907364E/pt unknown
- 1997-05-27 CA CA002251944A patent/CA2251944C/en not_active Expired - Lifetime
- 1997-05-27 DE DE69714739T patent/DE69714739T2/de not_active Expired - Lifetime
- 1997-05-27 BR BR9709271A patent/BR9709271A/pt not_active Application Discontinuation
- 1997-05-27 SK SK1639-98A patent/SK284131B6/sk not_active IP Right Cessation
- 1997-05-27 CN CNB971949611A patent/CN1142780C/zh not_active Expired - Lifetime
- 1997-05-27 AT AT97924103T patent/ATE222105T1/de active
- 1997-05-27 ES ES97924103T patent/ES2182079T3/es not_active Expired - Lifetime
- 1997-05-27 AU AU29675/97A patent/AU727219B2/en not_active Expired
- 1997-05-27 RU RU98123601/14A patent/RU2201754C2/ru active
- 1997-05-27 PL PL97330223A patent/PL189887B1/pl not_active IP Right Cessation
- 1997-05-27 UA UA98127026A patent/UA50772C2/uk unknown
- 1997-05-27 SI SI9730410T patent/SI0907364T1/xx unknown
- 1997-05-27 HU HU9902194A patent/HU225152B1/hu unknown
- 1997-05-27 IL IL12722297A patent/IL127222A/xx not_active IP Right Cessation
- 1997-05-27 DK DK97924103T patent/DK0907364T3/da active
- 1997-05-27 EP EP97924103A patent/EP0907364B1/en not_active Expired - Lifetime
- 1997-05-27 CN CNA2006101016820A patent/CN101006985A/zh active Pending
- 1997-05-27 TR TR1998/02483T patent/TR199802483T2/xx unknown
- 1997-05-27 CN CNA2004100033798A patent/CN1511532A/zh active Pending
- 1997-05-27 JP JP09541846A patent/JP2000511170A/ja active Pending
- 1997-05-27 WO PCT/GB1997/001432 patent/WO1997045124A1/en not_active Ceased
- 1997-05-27 NZ NZ332198A patent/NZ332198A/xx not_active IP Right Cessation
- 1997-05-28 EG EG47397A patent/EG24118A/xx active
- 1997-05-28 HR HR970299A patent/HRP970299B1/xx not_active IP Right Cessation
- 1997-05-28 MY MYPI97002306A patent/MY120120A/en unknown
- 1997-05-29 ZA ZA9704735A patent/ZA974735B/xx unknown
- 1997-05-30 AR ARP970102352A patent/AR003662A1/es active IP Right Grant
- 1997-05-30 ID IDP971846A patent/ID18352A/id unknown
- 1997-06-04 TW TW086107689A patent/TW550076B/zh not_active IP Right Cessation
-
1998
- 1998-11-27 NO NO19985539A patent/NO327801B1/no not_active IP Right Cessation
-
2006
- 2006-03-15 JP JP2006071695A patent/JP2006152006A/ja active Pending
-
2007
- 2007-02-09 JP JP2007030991A patent/JP2007119495A/ja active Pending
-
2011
- 2011-11-07 JP JP2011243832A patent/JP5888549B2/ja not_active Expired - Lifetime
-
2014
- 2014-06-12 JP JP2014121055A patent/JP2014167026A/ja not_active Withdrawn
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