DE69714739T2 - Arzneimittel mit verzögerter freisetzung, das ein dibenzothiazepinderivat enthält - Google Patents
Arzneimittel mit verzögerter freisetzung, das ein dibenzothiazepinderivat enthältInfo
- Publication number
- DE69714739T2 DE69714739T2 DE69714739T DE69714739T DE69714739T2 DE 69714739 T2 DE69714739 T2 DE 69714739T2 DE 69714739 T DE69714739 T DE 69714739T DE 69714739 T DE69714739 T DE 69714739T DE 69714739 T2 DE69714739 T2 DE 69714739T2
- Authority
- DE
- Germany
- Prior art keywords
- hydroxypropylmethylcellulose
- weight
- formulation according
- pharmaceutically acceptable
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 229940126601 medicinal product Drugs 0.000 title 1
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- -1 hydroxypropoxy Chemical group 0.000 claims description 49
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims description 44
- URKOMYMAXPYINW-UHFFFAOYSA-N quetiapine Chemical compound C1CN(CCOCCO)CCN1C1=NC2=CC=CC=C2SC2=CC=CC=C12 URKOMYMAXPYINW-UHFFFAOYSA-N 0.000 claims description 41
- 150000003839 salts Chemical class 0.000 claims description 32
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9611328.7A GB9611328D0 (en) | 1996-05-31 | 1996-05-31 | Pharmaceutical compositions |
| PCT/GB1997/001432 WO1997045124A1 (en) | 1996-05-31 | 1997-05-27 | Pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69714739D1 DE69714739D1 (de) | 2002-09-19 |
| DE69714739T2 true DE69714739T2 (de) | 2003-05-15 |
Family
ID=10794541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69714739T Expired - Lifetime DE69714739T2 (de) | 1996-05-31 | 1997-05-27 | Arzneimittel mit verzögerter freisetzung, das ein dibenzothiazepinderivat enthält |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP0907364B1 (enExample) |
| JP (5) | JP2000511170A (enExample) |
| CN (3) | CN1142780C (enExample) |
| AR (1) | AR003662A1 (enExample) |
| AT (1) | ATE222105T1 (enExample) |
| AU (1) | AU727219B2 (enExample) |
| BR (1) | BR9709271A (enExample) |
| CA (1) | CA2251944C (enExample) |
| CZ (1) | CZ293760B6 (enExample) |
| DE (1) | DE69714739T2 (enExample) |
| DK (1) | DK0907364T3 (enExample) |
| EG (1) | EG24118A (enExample) |
| ES (1) | ES2182079T3 (enExample) |
| GB (2) | GB9611328D0 (enExample) |
| HR (1) | HRP970299B1 (enExample) |
| HU (1) | HU225152B1 (enExample) |
| ID (1) | ID18352A (enExample) |
| IL (1) | IL127222A (enExample) |
| MY (1) | MY120120A (enExample) |
| NO (1) | NO327801B1 (enExample) |
| NZ (1) | NZ332198A (enExample) |
| PL (1) | PL189887B1 (enExample) |
| PT (1) | PT907364E (enExample) |
| RU (1) | RU2201754C2 (enExample) |
| SI (1) | SI0907364T1 (enExample) |
| SK (1) | SK284131B6 (enExample) |
| TR (1) | TR199802483T2 (enExample) |
| TW (1) | TW550076B (enExample) |
| UA (1) | UA50772C2 (enExample) |
| WO (1) | WO1997045124A1 (enExample) |
| ZA (1) | ZA974735B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9922271D0 (en) | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Formulation |
| SE0003126D0 (sv) * | 2000-09-05 | 2000-09-05 | Astrazeneca Ab | Method of treatment |
| JP2004525109A (ja) | 2001-02-15 | 2004-08-19 | キング・ファーマシューティカルズ・インコーポレイティッド | 安定化された甲状腺ホルモン医薬組成物、及びその製法 |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| SE0102855D0 (sv) * | 2001-08-27 | 2001-08-27 | Astrazeneca Ab | Method of treatment |
| EP1448169A1 (en) | 2001-11-07 | 2004-08-25 | Fujisawa Pharmaceutical Co., Ltd. | Method for improving dissolution of poorly dispersible medicaments |
| TW200735878A (en) * | 2005-11-18 | 2007-10-01 | Astrazeneca Ab | Pharmaceutical compositions |
| EP1976487A2 (en) | 2006-01-25 | 2008-10-08 | Astron Research Limited | Sustained release dosage form of phenothiazine derivatives containing channelizer |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| GB0618879D0 (en) * | 2006-09-26 | 2006-11-01 | Zysis Ltd | Pharmaceutical compositions |
| DE602007009036D1 (de) | 2007-02-14 | 2010-10-21 | Lesvi Laboratorios Sl | Pharmazeutische Zusammensetzungen mit Quetiapinfumarat |
| EP2131817A2 (en) | 2007-03-09 | 2009-12-16 | Synthon B.V. | Pharmaceutical composition of quetiapine fumarate |
| US20080287418A1 (en) * | 2007-05-16 | 2008-11-20 | Astrazeneca Ab | Extended Release Compositions and Methods for Their Manufacture |
| DK2262486T3 (da) | 2008-08-01 | 2013-03-25 | Krka Tovarna Zdravil D D Novo Mesto | Quetiapin sammensætning |
| EP2153834A3 (en) | 2008-08-07 | 2010-02-24 | Farmaprojects, S.A. | Extended release pharmaceutical compositions comprising quetiapine salts |
| DE102008046650A1 (de) | 2008-09-10 | 2010-03-11 | Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg | Quetiapin enthaltende Retardtablette |
| US20110280938A1 (en) * | 2009-01-05 | 2011-11-17 | Torrent Pharmaceuticals Limited | Sustained release pharmaceutical composition of quetiapine and process for preparation thereof |
| WO2010089259A2 (en) | 2009-02-04 | 2010-08-12 | Woerwag R&D Gmbh | Sustained release composition containing quetiapine |
| EP2233130A1 (en) * | 2009-03-23 | 2010-09-29 | Genepharm (Europe) Trading Limited | A sustained release oral composition of an antipsychotic agent |
| AR076907A1 (es) * | 2009-05-13 | 2011-07-20 | Wyeth Llc | Composiciones con liberacion rapida de farmaco |
| WO2011132008A2 (en) | 2010-04-22 | 2011-10-27 | EGIS Gyűgyszergyár Nyilvánosan Múködő Részvény társaság | Controlled release pharmaceutical composition |
| WO2011154118A1 (en) | 2010-06-07 | 2011-12-15 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Quetiapine prolonged-release tablets |
| DE102010033527A1 (de) | 2010-08-05 | 2012-02-09 | Acino Pharma Ag | Quetiapin-Tabletten |
| TR201008261A1 (tr) | 2010-10-08 | 2012-04-24 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Kontrollü salım gerçekleştiren ketiapin formülasyonları |
| CN102218042A (zh) * | 2011-05-26 | 2011-10-19 | 青岛黄海制药有限责任公司 | 富马酸喹硫平组合物的缓释片剂及其制备方法 |
| DE102011115690A1 (de) | 2011-10-11 | 2013-04-11 | Acino Pharma Ag | Quetiapin enthaltende Formulierungen |
| CN102406606B (zh) * | 2011-11-29 | 2013-01-23 | 海南美大制药有限公司 | 富马酸喹硫平脂质体固体制剂 |
| PL2822541T3 (pl) | 2012-09-10 | 2019-02-28 | Pharmathen S.A. | Kompozycja farmaceutyczna zawierająca nietypowy środek przeciwpsychotyczny i sposób jej wytwarzania |
| EP2848244A1 (en) | 2013-09-16 | 2015-03-18 | Yildiz Özsoy Erginer | Extended release tablet formulations of quetiapine |
| EP3310344A1 (en) * | 2015-06-19 | 2018-04-25 | Biotie Therapies, Inc. | Controlled-release tozadenant formulations |
| CN106187873B (zh) * | 2016-07-25 | 2019-11-05 | 宜春学院 | 一种芳胺基烷基氧类化合物及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| US4775535A (en) * | 1986-04-04 | 1988-10-04 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4756911A (en) * | 1986-04-16 | 1988-07-12 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| EP0266707B1 (en) * | 1986-11-03 | 1992-01-22 | Schering Corporation | Sustained release labetalol tablet |
| IE59540B1 (en) * | 1987-01-09 | 1994-03-09 | Elan Corp | Sustained release capsule or tablet formulation |
| GB8705574D0 (en) * | 1987-03-10 | 1987-04-15 | Ici Plc | Preparation of thiazepine compound |
| US4983398A (en) * | 1987-12-21 | 1991-01-08 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
| IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Dispensing devices powered by hydrogel |
| SE9003902D0 (sv) * | 1990-12-07 | 1990-12-07 | Astra Ab | Solid dosage forms of a drug |
| IT1256651B (it) * | 1992-12-11 | 1995-12-12 | Giancarlo Santus | Composizione farmaceutica a rilascio controllato in sospensione liquida |
| JP3116970B2 (ja) * | 1991-06-12 | 2000-12-11 | 三菱東京製薬株式会社 | ペミロラストカリウムの徐放性製剤 |
| IT1256393B (it) * | 1992-11-17 | 1995-12-04 | Inverni Della Beffa Spa | Forme matriciali multistrato per il rilascio controllato di principi attivi |
| US5393765A (en) * | 1993-12-13 | 1995-02-28 | Hoffmann-La Roche Inc. | Pharmaceutical compositions with constant erosion volume for zero order controlled release |
| EP0759745A4 (en) * | 1994-05-13 | 1997-11-19 | Smithkline Beecham Corp | METHOD AND COMPOSITION FOR INCREASING FIXATION OF CALCIUM |
-
1996
- 1996-05-31 GB GBGB9611328.7A patent/GB9611328D0/en active Pending
-
1997
- 1997-05-15 GB GBGB9709761.2A patent/GB9709761D0/en active Pending
- 1997-05-27 CN CNB971949611A patent/CN1142780C/zh not_active Expired - Lifetime
- 1997-05-27 HU HU9902194A patent/HU225152B1/hu unknown
- 1997-05-27 TR TR1998/02483T patent/TR199802483T2/xx unknown
- 1997-05-27 JP JP09541846A patent/JP2000511170A/ja active Pending
- 1997-05-27 IL IL12722297A patent/IL127222A/xx not_active IP Right Cessation
- 1997-05-27 EP EP97924103A patent/EP0907364B1/en not_active Expired - Lifetime
- 1997-05-27 PL PL97330223A patent/PL189887B1/pl not_active IP Right Cessation
- 1997-05-27 DK DK97924103T patent/DK0907364T3/da active
- 1997-05-27 AU AU29675/97A patent/AU727219B2/en not_active Expired
- 1997-05-27 RU RU98123601/14A patent/RU2201754C2/ru active
- 1997-05-27 WO PCT/GB1997/001432 patent/WO1997045124A1/en not_active Ceased
- 1997-05-27 SI SI9730410T patent/SI0907364T1/xx unknown
- 1997-05-27 CA CA002251944A patent/CA2251944C/en not_active Expired - Lifetime
- 1997-05-27 UA UA98127026A patent/UA50772C2/uk unknown
- 1997-05-27 BR BR9709271A patent/BR9709271A/pt not_active Application Discontinuation
- 1997-05-27 ES ES97924103T patent/ES2182079T3/es not_active Expired - Lifetime
- 1997-05-27 AT AT97924103T patent/ATE222105T1/de active
- 1997-05-27 DE DE69714739T patent/DE69714739T2/de not_active Expired - Lifetime
- 1997-05-27 NZ NZ332198A patent/NZ332198A/xx not_active IP Right Cessation
- 1997-05-27 CZ CZ19983880A patent/CZ293760B6/cs not_active IP Right Cessation
- 1997-05-27 CN CNA2004100033798A patent/CN1511532A/zh active Pending
- 1997-05-27 CN CNA2006101016820A patent/CN101006985A/zh active Pending
- 1997-05-27 PT PT97924103T patent/PT907364E/pt unknown
- 1997-05-27 SK SK1639-98A patent/SK284131B6/sk not_active IP Right Cessation
- 1997-05-28 HR HR970299A patent/HRP970299B1/xx not_active IP Right Cessation
- 1997-05-28 MY MYPI97002306A patent/MY120120A/en unknown
- 1997-05-28 EG EG47397A patent/EG24118A/xx active
- 1997-05-29 ZA ZA9704735A patent/ZA974735B/xx unknown
- 1997-05-30 AR ARP970102352A patent/AR003662A1/es active IP Right Grant
- 1997-05-30 ID IDP971846A patent/ID18352A/id unknown
- 1997-06-04 TW TW086107689A patent/TW550076B/zh not_active IP Right Cessation
-
1998
- 1998-11-27 NO NO19985539A patent/NO327801B1/no not_active IP Right Cessation
-
2006
- 2006-03-15 JP JP2006071695A patent/JP2006152006A/ja active Pending
-
2007
- 2007-02-09 JP JP2007030991A patent/JP2007119495A/ja active Pending
-
2011
- 2011-11-07 JP JP2011243832A patent/JP5888549B2/ja not_active Expired - Lifetime
-
2014
- 2014-06-12 JP JP2014121055A patent/JP2014167026A/ja not_active Withdrawn
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| 8364 | No opposition during term of opposition | ||
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