|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4263428A
(en)
|
1978-03-24 |
1981-04-21 |
The Regents Of The University Of California |
Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
|
|
US4289872A
(en)
|
1979-04-06 |
1981-09-15 |
Allied Corporation |
Macromolecular highly branched homogeneous compound based on lysine units
|
|
ZA811368B
(en)
|
1980-03-24 |
1982-04-28 |
Genentech Inc |
Bacterial polypedtide expression employing tryptophan promoter-operator
|
|
EP0052322B1
(de)
|
1980-11-10 |
1985-03-27 |
Gersonde, Klaus, Prof. Dr. |
Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
|
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
|
FR2504010B1
(fr)
|
1981-04-15 |
1985-10-25 |
Sanofi Sa |
Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
|
|
US4551433A
(en)
|
1981-05-18 |
1985-11-05 |
Genentech, Inc. |
Microbial hybrid promoters
|
|
JPS57206622A
(en)
|
1981-06-10 |
1982-12-18 |
Ajinomoto Co Inc |
Blood substitute
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
NZ201705A
(en)
|
1981-08-31 |
1986-03-14 |
Genentech Inc |
Recombinant dna method for production of hepatitis b surface antigen in yeast
|
|
DE3374837D1
(en)
|
1982-02-17 |
1988-01-21 |
Ciba Geigy Ag |
Lipids in the aqueous phase
|
|
US4671958A
(en)
|
1982-03-09 |
1987-06-09 |
Cytogen Corporation |
Antibody conjugates for the delivery of compounds to target sites
|
|
DE3218121A1
(de)
|
1982-05-14 |
1983-11-17 |
Leskovar, Peter, Dr.-Ing., 8000 München |
Arzneimittel zur tumorbehandlung
|
|
EP0102324A3
(de)
|
1982-07-29 |
1984-11-07 |
Ciba-Geigy Ag |
Lipide und Tenside in wässriger Phase
|
|
EP0101309B1
(en)
|
1982-08-12 |
1991-01-16 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Molecular cloning and characterization of a gene sequence coding for human relaxin
|
|
US5145962A
(en)
*
|
1982-08-12 |
1992-09-08 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Human pro relaxin polypeptides
|
|
US5179195A
(en)
|
1982-12-13 |
1993-01-12 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Human relaxin polypeptides
|
|
IL70414A
(en)
|
1982-12-13 |
1991-06-10 |
Florey Howard Inst |
Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors
|
|
US4512922A
(en)
|
1982-12-22 |
1985-04-23 |
Genentech, Inc. |
Purification and activity assurance of precipitated heterologous proteins
|
|
US4511503A
(en)
|
1982-12-22 |
1985-04-16 |
Genentech, Inc. |
Purification and activity assurance of precipitated heterologous proteins
|
|
US4511502A
(en)
|
1982-12-22 |
1985-04-16 |
Genentech, Inc. |
Purification and activity assurance of precipitated heterologous proteins
|
|
CA1341116C
(en)
|
1983-02-22 |
2000-10-17 |
Rae Lyn Burke |
Yeast expression systems with vectors having gapdh or pyk promoters and synthesis or foreign protein
|
|
US5089398A
(en)
|
1983-02-22 |
1992-02-18 |
Chiron Corporation |
Enhanced yeast transcription employing hybrid GAPDH promoter region constructs
|
|
US4876197A
(en)
|
1983-02-22 |
1989-10-24 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
|
JPS59166086A
(ja)
|
1983-03-09 |
1984-09-19 |
Teruhiko Beppu |
新規な発現型プラスミドとそれらを用いて仔牛プロキモシン遺伝子を大腸菌内で発現させる方法
|
|
US4755465A
(en)
|
1983-04-25 |
1988-07-05 |
Genentech, Inc. |
Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
|
|
US4859600A
(en)
|
1983-04-25 |
1989-08-22 |
Genentech, Inc. |
Recombinant procaryotic cell containing correctly processed human growth hormone
|
|
EP0127839B1
(en)
|
1983-05-27 |
1992-07-15 |
THE TEXAS A&M UNIVERSITY SYSTEM |
Method for producing a recombinant baculovirus expression vector
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
JPS607934A
(ja)
|
1983-06-29 |
1985-01-16 |
Dai Ichi Seiyaku Co Ltd |
リポソ−ムの製造方法
|
|
GB8317880D0
(en)
|
1983-07-01 |
1983-08-03 |
Searle & Co |
Structure and synthesis of interferons
|
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
|
US4689406A
(en)
|
1983-08-10 |
1987-08-25 |
Amgen |
Enhancement of microbial expression of polypeptides
|
|
US4870008A
(en)
|
1983-08-12 |
1989-09-26 |
Chiron Corporation |
Secretory expression in eukaryotes
|
|
ATE159858T1
(de)
|
1983-09-26 |
1997-11-15 |
Ehrenfeld Udo |
Mittel und erzeugnis für die diagnose und therapie von tumoren sowie zur behandlung von schwächen der zelligen und humoralen immunabwehr
|
|
DE3474511D1
(en)
|
1983-11-01 |
1988-11-17 |
Terumo Corp |
Pharmaceutical composition containing urokinase
|
|
JPS60118008A
(ja)
|
1983-11-28 |
1985-06-25 |
株式会社竹中工務店 |
コンクリ−ト直埋配線工法
|
|
ZA848495B
(en)
|
1984-01-31 |
1985-09-25 |
Idaho Res Found |
Production of polypeptides in insect cells
|
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
|
DE3587759T2
(de)
|
1984-05-11 |
1994-07-07 |
Chiron Corp., Emeryville, Calif. |
Erhöhte Hefetranskription unter Verwendung einer Hybridkonstruktion der Promotorregion.
|
|
US4880734A
(en)
|
1984-05-11 |
1989-11-14 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
|
GB8412564D0
(en)
|
1984-05-17 |
1984-06-20 |
Searle & Co |
Structure and properties
|
|
US4931373A
(en)
|
1984-05-25 |
1990-06-05 |
Zymogenetics, Inc. |
Stable DNA constructs for expression of α-1 antitrypsin
|
|
US4542225A
(en)
|
1984-08-29 |
1985-09-17 |
Dana-Farber Cancer Institute, Inc. |
Acid-cleavable compound
|
|
US4738921A
(en)
|
1984-09-27 |
1988-04-19 |
Eli Lilly And Company |
Derivative of the tryptophan operon for expression of fused gene products
|
|
US4659839A
(en)
|
1984-10-10 |
1987-04-21 |
Mallinckrodt, Inc. |
Coupling agents for radiolabeled antibody fragments
|
|
US4837148A
(en)
|
1984-10-30 |
1989-06-06 |
Phillips Petroleum Company |
Autonomous replication sequences for yeast strains of the genus pichia
|
|
GB8430252D0
(en)
|
1984-11-30 |
1985-01-09 |
Beecham Group Plc |
Compounds
|
|
EP0188256B1
(en)
|
1985-01-14 |
1991-08-21 |
NeoRx |
Metal radionuclide labeled proteins for diagnosis and therapy
|
|
EP0206448B1
(en)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
|
DE3676670D1
(de)
|
1985-06-26 |
1991-02-07 |
Cetus Corp |
Solubilisierung von proteinen fuer pharmazeutische zusammensetzungen mittels polymerkonjugierung.
|
|
PH25772A
(en)
|
1985-08-30 |
1991-10-18 |
Novo Industri As |
Insulin analogues, process for their preparation
|
|
US4680338A
(en)
|
1985-10-17 |
1987-07-14 |
Immunomedics, Inc. |
Bifunctional linker
|
|
UA41863C2
(uk)
|
1985-10-25 |
2001-10-15 |
Займодженетікс Інк. |
Спосіб одержання гетерологічного поліпептиду в еукаріотичних мікроорганізмах
|
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
|
US4835251A
(en)
|
1986-06-23 |
1989-05-30 |
Genetech, Inc. |
Method of chain combination
|
|
JPS63123383A
(ja)
|
1986-11-11 |
1988-05-27 |
Mitsubishi Kasei Corp |
ハイブリツドプロモ−タ−、発現調節ｄｎａ配列および発現ベクタ−
|
|
US5186933A
(en)
|
1986-12-30 |
1993-02-16 |
Baylor College Of Medicine |
Synthesis and immunogenicity of rotavirus genes using a baculovirus expression system
|
|
WO1988007082A1
(en)
|
1987-03-16 |
1988-09-22 |
American Biogenetic Sciences, Inc. |
Recombinant baculovirus occlusion bodies in vaccines and biological insecticides
|
|
DE3888561T2
(de)
|
1987-03-23 |
1994-09-01 |
Zymogenetics Inc |
Hohe Proteinsyntheserate in Hefe.
|
|
US5229490A
(en)
|
1987-05-06 |
1993-07-20 |
The Rockefeller University |
Multiple antigen peptide system
|
|
WO1989001037A1
(en)
|
1987-07-24 |
1989-02-09 |
Cetus Corporation |
Production of ricin toxins in a baculovirus-insect cell expression system
|
|
CA1317244C
(en)
|
1987-07-24 |
1993-05-04 |
Ernest Seigo Kawasaki |
Production of biologically active forms of csf using a baculovirus (acnpv)-insect cell expression system
|
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
|
US4929555A
(en)
|
1987-10-19 |
1990-05-29 |
Phillips Petroleum Company |
Pichia transformation
|
|
GB8725529D0
(en)
|
1987-10-30 |
1987-12-02 |
Delta Biotechnology Ltd |
Polypeptides
|
|
US4904584A
(en)
|
1987-12-23 |
1990-02-27 |
Genetics Institute, Inc. |
Site-specific homogeneous modification of polypeptides
|
|
CA1340772C
(en)
|
1987-12-30 |
1999-09-28 |
Patricia Tekamp-Olson |
Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
|
|
US4847325A
(en)
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
|
AU626840B2
(en)
|
1988-02-26 |
1992-08-13 |
Genentech Inc. |
Human relaxin formulation
|
|
US5674706A
(en)
|
1988-05-06 |
1997-10-07 |
Chiron Corporation |
High level expression of proteins in yeast
|
|
CA1324969C
(en)
|
1988-05-06 |
1993-12-07 |
Jeffrey R. Shuster |
High level expression of proteins in yeast
|
|
FR2631974B1
(fr)
|
1988-05-31 |
1992-12-11 |
Agronomique Inst Nat Rech |
Baculovirus modifie, son procede de preparation et son application en tant que vecteur d'expression de genes
|
|
WO1990001556A1
(en)
|
1988-08-05 |
1990-02-22 |
Mount Sinai School Of Medicine Of The City University Of New York |
In vivo infection of live insects with a recombinant baculovirus
|
|
GB8819453D0
(en)
|
1988-08-16 |
1988-09-21 |
Roy P |
Production of bluetongue virus non-structural proteins using baculovirus expression vector
|
|
NZ230425A
(en)
|
1988-09-02 |
1992-07-28 |
Molecular Eng Ass |
Production of paramyxovirus fusion (f) protein using recombinant baculovirus expression vector
|
|
GB8824591D0
(en)
|
1988-10-20 |
1988-11-23 |
Royal Free Hosp School Med |
Fractionation process
|
|
CA2345497A1
(en)
|
1988-10-28 |
1990-04-28 |
Genentech, Inc. |
Growth hormone variants and method for forming growth hormone variants
|
|
US6780613B1
(en)
|
1988-10-28 |
2004-08-24 |
Genentech, Inc. |
Growth hormone variants
|
|
JPH04504651A
(ja)
|
1988-11-18 |
1992-08-20 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
自然に存在しないアミノ酸をタンパク質に部位特異的に導入する方法
|
|
US5047335A
(en)
|
1988-12-21 |
1991-09-10 |
The Regents Of The University Of Calif. |
Process for controlling intracellular glycosylation of proteins
|
|
JP2989002B2
(ja)
|
1988-12-22 |
1999-12-13 |
キリン―アムジエン・インコーポレーテツド |
化学修飾顆粒球コロニー刺激因子
|
|
HUT56857A
(en)
|
1988-12-23 |
1991-10-28 |
Novo Nordisk As |
Human insulin analogues
|
|
US4902502A
(en)
|
1989-01-23 |
1990-02-20 |
Cetus Corporation |
Preparation of a polymer/interleukin-2 conjugate
|
|
US5514646A
(en)
|
1989-02-09 |
1996-05-07 |
Chance; Ronald E. |
Insulin analogs modified at position 29 of the B chain
|
|
AU5187190A
(en)
|
1989-02-23 |
1990-09-26 |
University Of Ottawa |
Improved baculovirus expression system capable of producing foreign gene proteins at high levels
|
|
WO1990010277A1
(en)
|
1989-02-24 |
1990-09-07 |
Cell Analysis Systems, Inc. |
Method and apparatus for determining a proliferation index of a cell sample
|
|
WO1990013540A1
(en)
|
1989-04-19 |
1990-11-15 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
US5324844A
(en)
|
1989-04-19 |
1994-06-28 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
US5122614A
(en)
|
1989-04-19 |
1992-06-16 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
ATE92107T1
(de)
|
1989-04-29 |
1993-08-15 |
Delta Biotechnology Ltd |
N-terminale fragmente von menschliches serumalbumin enthaltenden fusionsproteinen.
|
|
US5766883A
(en)
|
1989-04-29 |
1998-06-16 |
Delta Biotechnology Limited |
Polypeptides
|
|
CA2033070A1
(en)
|
1989-05-17 |
1990-11-18 |
Lois K. Miller |
Baculovirus expression vectors
|
|
ES2085297T3
(es)
|
1989-05-27 |
1996-06-01 |
Sumitomo Pharma |
Procedimiento para preparar derivados de poli(etilenglicol) y proteina modificada.
|
|
FR2649120B1
(fr)
|
1989-06-30 |
1994-01-28 |
Cayla |
Nouvelle souche et ses mutants de champignons filamenteux, procede de production de proteines recombinantes a l'aide de ladite souche et souches et proteines obtenues selon ce procede
|
|
US5312808A
(en)
|
1989-11-22 |
1994-05-17 |
Enzon, Inc. |
Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
|
|
US5162601A
(en)
|
1989-11-22 |
1992-11-10 |
The Upjohn Company |
Plant potyvirus expression vector with a gene for protease
|
|
US5219564A
(en)
|
1990-07-06 |
1993-06-15 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
|
US5074598A
(en)
|
1990-06-28 |
1991-12-24 |
Dayco Products, Inc. |
Hose construction, coupling unit and system therefor
|
|
FR2664905B1
(fr)
|
1990-07-18 |
1994-08-12 |
Agronomique Inst Nat Rech |
Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus.
|
|
WO1992001800A1
(en)
|
1990-07-20 |
1992-02-06 |
Chiron Corporation |
Method for integrative transformation of yeast using dispersed repetitive elements
|
|
EP0541721A4
(en)
|
1990-08-02 |
1993-12-29 |
Chiron Corporation |
Expression of human cmv glycoprotein-h using the baculovirus-insect cell expression system
|
|
CA2090969C
(en)
|
1990-09-04 |
2001-08-21 |
Russell Arthur Brierley |
Production of insulin-like growth factor-1 in methylotrophic yeast cells
|
|
CA2073511A1
(en)
|
1990-11-14 |
1992-05-29 |
Matthew R. Callstrom |
Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
DE69129154T2
(de)
|
1990-12-03 |
1998-08-20 |
Genentech, Inc., South San Francisco, Calif. |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
|
US5231178A
(en)
|
1991-01-16 |
1993-07-27 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Method for the purification of intact, correctly-folded insulin-like growth factor-1
|
|
JPH06506217A
(ja)
|
1991-03-18 |
1994-07-14 |
エンゾン，インコーポレーテッド |
ポリペプチドまたはグリコポリペプチドとポリマーとのヒドラジン含有結合体
|
|
AU1651992A
(en)
|
1991-03-19 |
1992-10-21 |
United States of America, as represented by the Secretary, U.S. Department of Commerce, The |
Expression of influenza nucleoprotein antigens in baculovirus
|
|
US5595732A
(en)
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
|
US6013433A
(en)
|
1991-04-26 |
2000-01-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Baculovirus expression vectors and recombinant antigens for detecting type-specific antibodies to herpes simplex virus
|
|
US5281698A
(en)
|
1991-07-23 |
1994-01-25 |
Cetus Oncology Corporation |
Preparation of an activated polymer ester for protein conjugation
|
|
US5290686A
(en)
|
1991-07-31 |
1994-03-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Expression of influenza a M2 protein in baculovirus
|
|
US5166191A
(en)
|
1991-08-19 |
1992-11-24 |
Genentech, Inc. |
Use of relaxin in cardiovascular therapy
|
|
IT1260468B
(it)
|
1992-01-29 |
1996-04-09 |
|
Metodo per mantenere l'attivita' di enzimi proteolitici modificati con polietilenglicole
|
|
US6256642B1
(en)
|
1992-01-29 |
2001-07-03 |
Microsoft Corporation |
Method and system for file system management using a flash-erasable, programmable, read-only memory
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
DE69312700T2
(de)
|
1992-04-14 |
1998-02-19 |
Cornell Res Foundation Inc |
Makromoleküle auf basis von dendritischen polymeren und verfahren zur herstellung
|
|
US5516657A
(en)
|
1992-05-11 |
1996-05-14 |
Cambridge Biotech Corporation |
Baculovirus vectors for expression of secretory and membrane-bound proteins
|
|
ZA933926B
(en)
|
1992-06-17 |
1994-01-03 |
Amgen Inc |
Polyoxymethylene-oxyethylene copolymers in conjuction with blomolecules
|
|
US6095713A
(en)
|
1992-06-24 |
2000-08-01 |
D & D Group Pty Ltd |
Engagement device and coupling member
|
|
WO1994004193A1
(en)
|
1992-08-21 |
1994-03-03 |
Enzon, Inc. |
Novel attachment of polyalkylene oxides to bio-effecting substances
|
|
US5382657A
(en)
|
1992-08-26 |
1995-01-17 |
Hoffmann-La Roche Inc. |
Peg-interferon conjugates
|
|
NZ250375A
(en)
|
1992-12-09 |
1995-07-26 |
Ortho Pharma Corp |
Peg hydrazone and peg oxime linkage forming reagents and protein derivatives
|
|
US5298643A
(en)
|
1992-12-22 |
1994-03-29 |
Enzon, Inc. |
Aryl imidate activated polyalkylene oxides
|
|
AU6029594A
(en)
|
1993-01-15 |
1994-08-15 |
Enzon, Inc. |
Factor viii - polymeric conjugates
|
|
US5349001A
(en)
|
1993-01-19 |
1994-09-20 |
Enzon, Inc. |
Cyclic imide thione activated polyalkylene oxides
|
|
US5321095A
(en)
|
1993-02-02 |
1994-06-14 |
Enzon, Inc. |
Azlactone activated polyalkylene oxides
|
|
US5532142A
(en)
|
1993-02-12 |
1996-07-02 |
Board Of Regents, The University Of Texas System |
Method of isolation and purification of fusion polypeptides
|
|
IL104734A0
(en)
|
1993-02-15 |
1993-06-10 |
Univ Bar Ilan |
Bioactive conjugates of cellulose with amino compounds
|
|
AU7097094A
(en)
|
1993-06-01 |
1994-12-20 |
Enzon, Inc. |
Carbohydrate-modified polymer conjugates with erythropoietic activity
|
|
WO1995000645A2
(en)
|
1993-06-21 |
1995-01-05 |
Genentech, Inc. |
Process for producing relaxin
|
|
AU7113594A
(en)
|
1993-06-21 |
1995-01-17 |
Enzon, Inc. |
Site specific synthesis of conjugated peptides
|
|
GB9317618D0
(en)
|
1993-08-24 |
1993-10-06 |
Royal Free Hosp School Med |
Polymer modifications
|
|
US5762939A
(en)
|
1993-09-13 |
1998-06-09 |
Mg-Pmc, Llc |
Method for producing influenza hemagglutinin multivalent vaccines using baculovirus
|
|
US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5491076A
(en)
|
1993-11-01 |
1996-02-13 |
The Texas A&M University System |
Expression of foreign genes using a replicating polyprotein producing virus vector
|
|
US5605792A
(en)
|
1993-11-04 |
1997-02-25 |
The Ohio State University Research Foundation |
Infectious bursal disease virus VP2 fusion protein expressed by baculovirus, use as diagnostic
|
|
US5951974A
(en)
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
|
HUT75533A
(en)
|
1993-11-10 |
1997-05-28 |
Schering Corp |
Improved interferon polymer conjugates
|
|
US5446090A
(en)
|
1993-11-12 |
1995-08-29 |
Shearwater Polymers, Inc. |
Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
|
|
US6852507B1
(en)
|
1994-01-31 |
2005-02-08 |
L'institut National De La Recherche Agronomique |
Recombinant baculovirus and use thereof in the production of monoclonal antibodies
|
|
FR2715664B1
(fr)
|
1994-01-31 |
1996-04-12 |
Proteine Performance Sa |
Baculovirus recombinant et son utilisation pour la production d'anticorps monoclonaux.
|
|
JP3090586B2
(ja)
|
1994-03-15 |
2000-09-25 |
片倉工業株式会社 |
システインプロテアーゼ遺伝子欠損バキュロウイルスおよびその製造法並びにこれを利用する有用タンパク質の製造法
|
|
US5473034A
(en)
|
1994-03-18 |
1995-12-05 |
Hyogo Prefectural Government |
Method for producing protein-synthetic polymer conjugate and said conjugate produced thereby
|
|
US5629384A
(en)
|
1994-05-17 |
1997-05-13 |
Consiglio Nazionale Delle Ricerche |
Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces
|
|
US5686110A
(en)
|
1994-06-02 |
1997-11-11 |
Enzon, Inc. |
Water soluble complex of an alkyl or olefinic end capped polyalkylene oxide and a water insoluble substance
|
|
US5730990A
(en)
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
|
US6403375B1
(en)
|
1994-08-24 |
2002-06-11 |
Boyce Thompson Institute For Plant Research, Inc. |
Establishment of Trichoplusia ni cell lines in serum-free medium for recombinant protein and baculovirus production
|
|
US5650234A
(en)
|
1994-09-09 |
1997-07-22 |
Surface Engineering Technologies, Division Of Innerdyne, Inc. |
Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
|
|
US5871986A
(en)
|
1994-09-23 |
1999-02-16 |
The General Hospital Corporation |
Use of a baculovirus to express and exogenous gene in a mammalian cell
|
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
|
EP0788375A2
(en)
|
1994-11-09 |
1997-08-13 |
Robin Ewart Offord |
Functionalized polymers for site-specific attachment
|
|
US5738846A
(en)
|
1994-11-10 |
1998-04-14 |
Enzon, Inc. |
Interferon polymer conjugates and process for preparing the same
|
|
US5932462A
(en)
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
|
EP0842275A1
(en)
|
1995-02-17 |
1998-05-20 |
Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) |
PRODUCTION OF BIOLOGICALLY ACTIVE RECOMBINANT BOVINE FOLLICLE STIMULATING HORMONE (REC bFSH) IN THE BACULOVIRUS EXPRESSION SYSTEM
|
|
FR2732035B1
(fr)
|
1995-03-23 |
1997-05-30 |
Agronomique Inst Nat Rech |
Procede de regulation de l'expression d'un gene dans un baculovirus, par un site de fixation d'un recepteur de l'acide retinoique, et vecteur pour la mise en oeuvre du dit procede
|
|
US6184344B1
(en)
|
1995-05-04 |
2001-02-06 |
The Scripps Research Institute |
Synthesis of proteins by native chemical ligation
|
|
NZ308772A
(en)
|
1995-05-17 |
1999-04-29 |
Du Pont |
Recombinant baculovirus insecticides
|
|
US5911997A
(en)
|
1995-06-07 |
1999-06-15 |
Connetics Corporation |
Relaxin-like factor and methods and uses thereof
|
|
AU5893696A
(en)
|
1995-06-07 |
1996-12-30 |
Novo Nordisk A/S |
Modification of polypeptides
|
|
US5833948A
(en)
|
1995-06-15 |
1998-11-10 |
Bracco Research S.A. |
Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
|
|
US5672662A
(en)
|
1995-07-07 |
1997-09-30 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
|
|
CA2229479C
(en)
|
1995-08-15 |
2010-03-30 |
Connective Therapeutics, Inc. |
Method of promoting angiogenesis
|
|
GB9526733D0
(en)
|
1995-12-30 |
1996-02-28 |
Delta Biotechnology Ltd |
Fusion proteins
|
|
US5861279A
(en)
|
1996-01-17 |
1999-01-19 |
Schering Corporation |
Baculovirus expression system for human interleukin 5 receptor and method of screening for interleukin 5 antagonists
|
|
AU1690697A
(en)
|
1996-01-17 |
1997-08-11 |
Schering Corporation |
Baculovirus expression system for human interleukin 5 receptor and method of screening for interleukin antagonists
|
|
US5747639A
(en)
|
1996-03-06 |
1998-05-05 |
Amgen Boulder Inc. |
Use of hydrophobic interaction chromatography to purify polyethylene glycols
|
|
TW517067B
(en)
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
|
AU3908597A
(en)
|
1996-08-02 |
1998-02-25 |
Ortho-Mcneil Pharmaceutical, Inc. |
Polypeptides having a single covalently bound n-terminal water-soluble polymer
|
|
US5980948A
(en)
|
1996-08-16 |
1999-11-09 |
Osteotech, Inc. |
Polyetherester copolymers as drug delivery matrices
|
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
US5998595A
(en)
|
1996-11-05 |
1999-12-07 |
Wako Pure Chemical Industries, Ltd. |
Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups
|
|
WO1998025963A1
(en)
|
1996-12-13 |
1998-06-18 |
Chiron Corporation |
Analysis and separation of platelet-derived growth factor proteins
|
|
AU5773798A
(en)
|
1997-01-29 |
1998-08-18 |
Polymasc Pharmaceuticals Plc |
Pegylation process
|
|
GB9703406D0
(en)
|
1997-02-19 |
1997-04-09 |
Chiron Spa |
Expression of heterologous proteins
|
|
EP0974111B1
(en)
|
1997-04-11 |
2003-01-08 |
California Institute Of Technology |
Apparatus and method for automated protein design
|
|
JP2002505574A
(ja)
|
1997-04-30 |
2002-02-19 |
エンゾン，インコーポレイテッド |
ポリアルキレンオキシド修飾された単鎖ポリペプチド
|
|
US5990237A
(en)
|
1997-05-21 |
1999-11-23 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
|
|
US6583267B2
(en)
|
1997-06-06 |
2003-06-24 |
Kyowa Hakko Kogyo Co., Ltd. |
Chemically modified polypeptides
|
|
DE19726167B4
(de)
|
1997-06-20 |
2008-01-24 |
Sanofi-Aventis Deutschland Gmbh |
Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
|
|
US5965393A
(en)
|
1997-07-01 |
1999-10-12 |
National Institute Of Immunology |
Method for enhancing foreign gene expression in baculovirus expression vector system
|
|
IL133974A0
(en)
|
1997-07-14 |
2001-04-30 |
Bolder Biotechnology Inc |
Derivatives of growth hormone and related proteins
|
|
GB9715660D0
(en)
|
1997-07-25 |
1997-10-01 |
Zeneca Ltd |
Proteins
|
|
EP1003889A1
(en)
|
1997-08-05 |
2000-05-31 |
Chiron Corporation |
NOVEL $i(PICHIA PASTORIS) GENE SEQUENCES AND METHODS FOR THEIR USE
|
|
DE19735593C2
(de)
|
1997-08-15 |
1999-08-26 |
Hepavec Ag Fuer Gentherapie |
Hüllprotein-modifizierter Baculovirus-Vektor für die Gentherapie
|
|
US6090584A
(en)
|
1997-08-21 |
2000-07-18 |
University Technologies International Inc. |
Baculovirus artificial chromosomes and methods of use
|
|
US5989868A
(en)
|
1997-09-12 |
1999-11-23 |
The Board Of Regents Of The University Of Oklahoma |
Fusion protein systems designed to increase soluble cytoplasmic expression of heterologous proteins in esherichia coli
|
|
DK1015576T3
(da)
|
1997-09-16 |
2005-08-29 |
Egea Biosciences Llc |
Fremgangsmåde til fuldstændig kemisk syntese og aggregering af gener og genomer
|
|
AU752037B2
(en)
|
1997-09-26 |
2002-09-05 |
Uab Research Foundation |
Reduced antigenic cells and uses therefor
|
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
US6201072B1
(en)
|
1997-10-03 |
2001-03-13 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
DE19748489A1
(de)
|
1997-11-03 |
1999-05-06 |
Roche Diagnostics Gmbh |
Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
|
|
US6448369B1
(en)
|
1997-11-06 |
2002-09-10 |
Shearwater Corporation |
Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation
|
|
EP0924298A1
(en)
|
1997-12-18 |
1999-06-23 |
Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) |
Protein expression in baculovirus vector expression systems
|
|
US5981709A
(en)
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
|
US5985263A
(en)
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
|
US6225060B1
(en)
|
1998-03-04 |
2001-05-01 |
Onyx Pharmaceuticals, Inc. |
Baculovirus expression system and method for high throughput expression of genetic material
|
|
ATE279430T1
(de)
|
1998-03-05 |
2004-10-15 |
Chiron Corp |
Verfahren zur verbesserung der serum halbwertszeit von biologisch aktiven molekülen
|
|
ATE268609T1
(de)
|
1998-03-12 |
2004-06-15 |
Nektar Therapeutics Al Corp |
Polyethylenglycolderivate mit benachbarten reaktiven gruppen
|
|
KR100264953B1
(ko)
|
1998-04-03 |
2001-03-02 |
박현우 |
재조합 베큘로바이러스, 이의 제조방법 및 이를 포함하는 미생물 살충제
|
|
US6451986B1
(en)
|
1998-06-22 |
2002-09-17 |
Immunex Corporation |
Site specific protein modification
|
|
US6168932B1
(en)
|
1998-07-13 |
2001-01-02 |
Parker Hughes Institute |
Recombinant DTctGMCSF fusion toxin in a baculovirus expression vector system
|
|
US6245528B1
(en)
|
1998-07-28 |
2001-06-12 |
Academia Sinica |
Latent baculovirus expression system
|
|
US6368825B1
(en)
|
1998-08-10 |
2002-04-09 |
Academia Sinica |
Baculovirus containing minimal CMV promoter
|
|
DE69936322T2
(de)
|
1998-08-28 |
2008-02-21 |
Amylin Pharmaceuticals, Inc., San Diego |
Polyamideketten von genauer Länge und deren Konjugate mit Proteinen
|
|
US6251863B1
(en)
|
1998-09-08 |
2001-06-26 |
Samuel K. Yue |
Method of preventing and treating symptoms of aging and neurodegenerative dysfunctions with relaxin
|
|
WO2000020032A1
(en)
|
1998-10-06 |
2000-04-13 |
Trustees Of Dartmouth College |
RECOMBINANT CAT ALLERGEN, Fel dI, EXPRESSED IN BACULOVIRUS FOR DIAGNOSIS AND TREATMENT OF CAT ALLERGY
|
|
US6420339B1
(en)
|
1998-10-14 |
2002-07-16 |
Amgen Inc. |
Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
|
|
US6403312B1
(en)
|
1998-10-16 |
2002-06-11 |
Xencor |
Protein design automatic for protein libraries
|
|
WO2000026354A1
(en)
|
1998-10-30 |
2000-05-11 |
Novozymes A/S |
Glycosylated proteins having reduced allergenicity
|
|
US6451346B1
(en)
|
1998-12-23 |
2002-09-17 |
Amgen Inc |
Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
|
|
US6281211B1
(en)
|
1999-02-04 |
2001-08-28 |
Euro-Celtique S.A. |
Substituted semicarbazides and the use thereof
|
|
EP1177311B1
(en)
|
1999-03-17 |
2014-11-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
In vitro macromolecule biosynthesis methods using exogenous amino acids and a novel atp regeneration system
|
|
US6994986B2
(en)
|
1999-03-17 |
2006-02-07 |
The Board Of Trustees Of The Leland Stanford University |
In vitro synthesis of polypeptides by optimizing amino acid metabolism
|
|
US6342216B1
(en)
|
1999-03-17 |
2002-01-29 |
The Board Of Regents, The University Of Texas System |
Therapy of cancer by insect cells containing recombinant baculovirus encoding genes
|
|
US6337191B1
(en)
|
1999-03-22 |
2002-01-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Vitro protein synthesis using glycolytic intermediates as an energy source
|
|
JP2002542349A
(ja)
|
1999-04-16 |
2002-12-10 |
ダブリューエム・マーシュ・ライス・ユニバーシティー |
ポリ（プロピレンフマラート）−ジアクリレートマクロマーで交差結合された生体分解性のポリ（プロピレンフマラート）ネットワーク
|
|
US6261805B1
(en)
|
1999-07-15 |
2001-07-17 |
Boyce Thompson Institute For Plant Research, Inc. |
Sialyiation of N-linked glycoproteins in the baculovirus expression vector system
|
|
US6485937B1
(en)
|
1999-10-15 |
2002-11-26 |
The Rockefeller University |
System for rapid generation of recombinant baculovirus-based expression vectors for silkworm larvae
|
|
US6348558B1
(en)
|
1999-12-10 |
2002-02-19 |
Shearwater Corporation |
Hydrolytically degradable polymers and hydrogels made therefrom
|
|
US6376604B2
(en)
|
1999-12-22 |
2002-04-23 |
Shearwater Corporation |
Method for the preparation of 1-benzotriazolylcarbonate esters of poly(ethylene glycol)
|
|
MXPA02006216A
(es)
|
1999-12-22 |
2004-02-26 |
Nektar Therapeutics Al Corp |
Derivados estericamente impedidos de polimeros solubles en agua.
|
|
US6413507B1
(en)
|
1999-12-23 |
2002-07-02 |
Shearwater Corporation |
Hydrolytically degradable carbamate derivatives of poly (ethylene glycol)
|
|
US6646110B2
(en)
|
2000-01-10 |
2003-11-11 |
Maxygen Holdings Ltd. |
G-CSF polypeptides and conjugates
|
|
ATE362770T1
(de)
|
2000-02-09 |
2007-06-15 |
Bas Medical Inc |
Verwendung von relaxin zur behandlung von durch gefässverengung bedingten erkrankungen
|
|
WO2001062827A2
(en)
|
2000-02-22 |
2001-08-30 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
|
AU2001257577A1
(en)
|
2000-02-28 |
2001-09-03 |
Shearwater Corporation |
Water-soluble polymer conjugates of artelinic acid
|
|
US6586207B2
(en)
|
2000-05-26 |
2003-07-01 |
California Institute Of Technology |
Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues
|
|
GB0012997D0
(en)
|
2000-05-26 |
2000-07-19 |
Eurogene Limited |
Gene delivery
|
|
JP2002030098A
(ja)
|
2000-07-17 |
2002-01-29 |
Institute Of Immunology Co Ltd |
バキュロウィルスの発芽ウイルスからウイルスエンベロープを回収する方法
|
|
AU2001273385B2
(en)
|
2000-09-08 |
2005-04-07 |
Gryphon Therapeutics, Inc. |
Polymer-modified synthetic proteins
|
|
US6436386B1
(en)
|
2000-11-14 |
2002-08-20 |
Shearwater Corporation |
Hydroxyapatite-targeting poly (ethylene glycol) and related polymers
|
|
TW593427B
(en)
|
2000-12-18 |
2004-06-21 |
Nektar Therapeutics Al Corp |
Synthesis of high molecular weight non-peptidic polymer derivatives
|
|
TWI246524B
(en)
|
2001-01-19 |
2006-01-01 |
Shearwater Corp |
Multi-arm block copolymers as drug delivery vehicles
|
|
DK2322631T3
(en)
|
2001-04-19 |
2015-01-12 |
Scripps Research Inst |
Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar
|
|
GB0113657D0
(en)
|
2001-06-05 |
2001-07-25 |
Geneprot Inc |
Improved native chemical ligation with three or more components
|
|
US20040138412A1
(en)
|
2001-09-07 |
2004-07-15 |
Paolo Botti |
Extended native chemical ligation
|
|
AUPR814401A0
(en)
*
|
2001-10-08 |
2001-11-01 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Human 3 relaxin
|
|
US6908963B2
(en)
|
2001-10-09 |
2005-06-21 |
Nektar Therapeutics Al, Corporation |
Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
|
|
EP1446438A2
(en)
|
2001-11-07 |
2004-08-18 |
Nektar Therapeutics Al, Corporation |
Branched polymers and their conjugates
|
|
EP1456225A2
(en)
|
2001-11-14 |
2004-09-15 |
Geneprot, Inc. |
Extended native chemical ligation of three or more peptide fragments
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
DE60328587D1
(de)
|
2002-02-15 |
2009-09-10 |
Univ New York State Res Found |
RIBOZYME MIT BREITER tRNA-AMINOACYLIERUNGSWIRKUNG
|
|
ES2566761T3
(es)
|
2002-05-30 |
2016-04-15 |
The Scripps Research Institute |
Ligación de azidas y acetilenos catalizada por cobre
|
|
US7432092B2
(en)
|
2002-10-16 |
2008-10-07 |
The Scripps Research Institute |
Site specific incorporation of keto amino acids into proteins
|
|
CA2500653A1
(en)
|
2002-10-16 |
2004-04-29 |
The Scripps Research Institute |
Glycoprotein synthesis
|
|
EP1583816A4
(en)
|
2002-12-22 |
2007-06-13 |
Scripps Research Inst |
PROTEIN ARRAYS
|
|
KR101171397B1
(ko)
*
|
2003-04-17 |
2012-08-07 |
더 스크립스 리서치 인스티튜트 |
진핵 유전자 코드의 확장
|
|
AU2003903124A0
(en)
|
2003-06-20 |
2003-07-10 |
Mark Del Borgo |
Analogues of heteromeric proteins
|
|
WO2005007870A2
(en)
|
2003-07-07 |
2005-01-27 |
The Scripps Research Institute |
COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF
|
|
ES2301099T3
(es)
|
2003-07-07 |
2008-06-16 |
The Scripps Research Institute |
Composiciones de parejas ortogonales lisil-arnt y aminoacil-arnt sintetasa y usos de las mismas.
|
|
EP1658366A4
(en)
|
2003-07-07 |
2006-08-09 |
Scripps Research Inst |
COMPOSITIONS OF ORTHOGONAL GLUTAMYL-TRNA AND AMINOACYL-TRNA-SYNTHETASEPAARES AND THEIR USES
|
|
ES2737837T3
(es)
|
2003-10-09 |
2020-01-16 |
Ambrx Inc |
Derivados poliméricos
|
|
US8778880B2
(en)
|
2004-02-02 |
2014-07-15 |
Ambrx, Inc. |
Human growth hormone modified at position 35
|
|
KR101699142B1
(ko)
|
2004-06-18 |
2017-01-23 |
암브룩스, 인코포레이티드 |
신규 항원-결합 폴리펩티드 및 이의 용도
|
|
US7638299B2
(en)
|
2004-07-21 |
2009-12-29 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
US20060052304A1
(en)
*
|
2004-09-02 |
2006-03-09 |
Bas Medical, Inc. |
Method for remodeling bone and related sutures
|
|
WO2006068802A2
(en)
|
2004-12-22 |
2006-06-29 |
Ambrx, Inc. |
COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF
|
|
US8080391B2
(en)
|
2004-12-22 |
2011-12-20 |
Ambrx, Inc. |
Process of producing non-naturally encoded amino acid containing high conjugated to a water soluble polymer
|
|
EP2284191A3
(en)
|
2004-12-22 |
2011-07-20 |
Ambrx, Inc. |
Process for the preparation of hGH
|
|
MX2007007590A
(es)
|
2004-12-22 |
2007-12-10 |
Ambrx Inc |
Composiciones que contienen, metodos que involucran y usos de aminoacidos no naturales y polipeptidos.
|
|
WO2006071840A2
(en)
|
2004-12-22 |
2006-07-06 |
Ambrx, Inc. |
Formulations of human growth hormone comprising a non-naturally encoded amino acid
|
|
US7883858B2
(en)
*
|
2005-01-27 |
2011-02-08 |
Institute For Systems Biology |
Methods for identifying and monitoring drug side effects
|
|
CA2609205A1
(en)
|
2005-06-03 |
2006-12-14 |
Ambrx, Inc. |
Improved human interferon molecules and their uses
|
|
MX2007015106A
(es)
|
2005-06-03 |
2008-02-15 |
Ambrx Inc |
Incorporacion de aminoacidos codificadores de manera no natural en proteinas.
|
|
WO2007021297A1
(en)
|
2005-08-18 |
2007-02-22 |
Ambrx, Inc. |
COMPOSITIONS OF tRNA AND USES THEREOF
|
|
US20090088365A1
(en)
|
2005-11-02 |
2009-04-02 |
Roberto Mariani |
Biosynthetic Polypeptide Fusion Inhibitors
|
|
HRP20110404T1
(hr)
|
2005-11-08 |
2011-08-31 |
Ambrx |
Ubrzivači za modifikaciju ne-prirodnih aminokiselina i polipeptida ne-prirodnih aminokiselina
|
|
US20090018029A1
(en)
|
2005-11-16 |
2009-01-15 |
Ambrx, Inc. |
Methods and Compositions Comprising Non-Natural Amino Acids
|
|
ES2529065T3
(es)
|
2005-12-14 |
2015-02-16 |
Ambrx, Inc. |
Composiciones que contienen, procedimientos que implican y usos de aminoácidos no naturales y polipéptidos
|
|
CA2632832A1
(en)
|
2005-12-30 |
2007-07-12 |
Ambrx, Inc. |
Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
|
|
JP2009523815A
(ja)
|
2006-01-19 |
2009-06-25 |
アンブルックス，インコーポレイテッド |
免疫原性が調節された非天然アミノ酸ポリペプチド
|
|
ES2432391T3
(es)
*
|
2006-03-09 |
2013-12-03 |
The Scripps Research Institute |
Sistema para la expresión de componentes de traducción ortogonales en células huésped eubacterianas
|
|
WO2007115414A1
(en)
*
|
2006-04-11 |
2007-10-18 |
University Of Guelph |
Modified h2 relaxin for tumor suppression
|
|
US8035498B2
(en)
|
2006-08-15 |
2011-10-11 |
Terry Pennisi |
Wireless monitoring system with a self-powered transmitter
|
|
DK2615108T3
(en)
|
2006-09-08 |
2017-01-30 |
Ambrx Inc |
Modified human plasma polypeptide or fc scaffolds and their applications
|
|
PT2061878E
(pt)
|
2006-09-08 |
2014-04-22 |
Ambrx Inc |
Supressor híbrido arnt para células de vertebrados
|
|
NZ574673A
(en)
|
2006-09-08 |
2012-02-24 |
Ambrx Inc |
Site specific incorporation of non-natural amino acids by vertebrate cells
|
|
DK2064333T3
(da)
|
2006-09-08 |
2014-05-05 |
Ambrx Inc |
Suppressor-trna-transkription i hvirveldyrceller
|
|
JP2010512800A
(ja)
*
|
2006-12-18 |
2010-04-30 |
アンブルックス，インコーポレイテッド |
非天然のアミノ酸およびポリペプチドを含んでいる組成物、これらが関連する方法、ならびにこれらの利用
|
|
US20100098630A1
(en)
|
2006-12-28 |
2010-04-22 |
Ambrx, Inc. |
Phenazine and Quinoxaline Substituted Amino Acids and Polypeptides
|
|
PL2068909T3
(pl)
|
2007-03-30 |
2012-09-28 |
Ambrx Inc |
Modyfikowane polipeptydy fgf-21 i ich zastosowanie
|
|
EP2076533B1
(en)
|
2007-05-02 |
2014-10-08 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
|
WO2008148839A2
(en)
|
2007-06-08 |
2008-12-11 |
Ascendis Pharma As |
Long-acting polymeric prodrugs of exendin
|
|
CA2707840A1
(en)
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
|
US20110178029A1
(en)
|
2007-09-14 |
2011-07-21 |
Ambrx, Inc. |
Modified Human Apolipoprotein A-1 and Their Uses
|
|
WO2009052435A1
(en)
|
2007-10-19 |
2009-04-23 |
Ambrx, Inc. |
Anti-tnfri polypeptides and their uses
|
|
US9056922B2
(en)
*
|
2007-10-30 |
2015-06-16 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Chimeric relaxin polypeptides comprising an A and B chain derived from different relaxin family peptides
|
|
CA2704494A1
(en)
*
|
2007-11-02 |
2009-05-14 |
The Scripps Research Institute |
Directed evolution using proteins comprising unnatural amino acids
|
|
US8946148B2
(en)
*
|
2007-11-20 |
2015-02-03 |
Ambrx, Inc. |
Modified insulin polypeptides and their uses
|
|
US9938333B2
(en)
|
2008-02-08 |
2018-04-10 |
Ambrx, Inc. |
Modified leptin polypeptides and their uses
|
|
WO2010051056A2
(en)
|
2008-03-11 |
2010-05-06 |
Ambrx, Inc. |
ANTI-FcεRI POLYPEPTIDES AND THEIR USES
|
|
WO2009117622A2
(en)
|
2008-03-19 |
2009-09-24 |
Ambrx, Inc. |
Modified fgf-23 polypeptides and their uses
|
|
JP5651586B2
(ja)
*
|
2008-05-16 |
2015-01-14 |
コーセラ，インコーポレーテッド |
急性心不全に伴う呼吸困難のリラキシンによる治療
|
|
WO2010006214A1
(en)
|
2008-07-09 |
2010-01-14 |
Ambrx, Inc. |
Fgf-21 neutralizing antibodies and their uses
|
|
PL2318029T3
(pl)
|
2008-07-23 |
2018-03-30 |
Elanco Us Inc. |
Zmodyfikowane polipeptydy bydlęcego G-CSF i ich zastosowania
|
|
CA2738033C
(en)
|
2008-09-26 |
2019-11-26 |
Ambrx, Inc. |
Non-natural amino acid replication-dependent microorganisms and vaccines
|
|
US8278418B2
(en)
|
2008-09-26 |
2012-10-02 |
Ambrx, Inc. |
Modified animal erythropoietin polypeptides and their uses
|
|
JP5090330B2
(ja)
|
2008-12-26 |
2012-12-05 |
Ｋｄｄｉ株式会社 |
画像処理装置、画像処理方法およびプログラム
|
|
BR112012015461A2
(pt)
|
2009-12-21 |
2017-01-10 |
Ambrx Inc |
polipeptídeos de somatotropina boviina modificados e seus usos
|
|
US20120283172A1
(en)
|
2009-12-21 |
2012-11-08 |
Ambrx, Inc. |
Modified porcine somatotropin polypeptides and their uses
|
|
WO2011079293A1
(en)
|
2009-12-23 |
2011-06-30 |
Ambrx, Inc |
Tumor necrosis factor-related apoptosis inducing ligand polypeptides and their uses
|
|
US9400699B2
(en)
|
2010-07-28 |
2016-07-26 |
Orange |
Data communication between modules
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
EP3572091B1
(en)
*
|
2010-08-17 |
2023-12-13 |
Ambrx, Inc. |
Modified relaxin polypeptides and their uses
|
|
EP2714685B1
(en)
|
2011-05-27 |
2016-10-19 |
Ambrx, Inc. |
Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives
|
|
KR102179369B1
(ko)
|
2011-05-27 |
2020-11-16 |
암브룩스, 인코포레이티드 |
비-천연 아미노산 연결된 돌라스타틴 유도체를 함유하는 조성물, 이를 수반하는 방법, 및 용도
|
|
WO2013068874A1
(en)
|
2011-11-11 |
2013-05-16 |
Pfizer Inc. |
Antibody-drug conjugates
|
|
US20150031864A1
(en)
|
2012-02-29 |
2015-01-29 |
Ambrx, Inc. |
Modified Adiponectin Polypeptides and Their Uses
|
|
CN104245722A
(zh)
|
2012-02-29 |
2014-12-24 |
Ambrx公司 |
白细胞介素-10多肽结合物和其用途
|
|
WO2013130814A1
(en)
|
2012-02-29 |
2013-09-06 |
Ambrx, Inc. |
Novel prodrug containing molecule compostions and their uses
|
|
CN104245720A
(zh)
|
2012-02-29 |
2014-12-24 |
Ambrx公司 |
白细胞介素-3多肽结合物和其用途
|
|
US9206927B2
(en)
|
2012-05-18 |
2015-12-08 |
Brian K. Carter |
Utility conduit supporting device, system, and method
|
|
KR102143664B1
(ko)
|
2012-06-07 |
2020-08-11 |
암브룩스, 인코포레이티드 |
전립선 특이적 막 항원 항체 약물 접합체
|
|
CA2876706A1
(en)
|
2012-06-14 |
2013-12-19 |
Ambrx, Inc. |
Anti-psma antibodies conjugated to nuclear receptor ligand polypeptides
|
|
SG11201408494UA
(en)
|
2012-06-19 |
2015-02-27 |
Ambrx Inc |
Anti-cd70 antibody drug conjugates
|
|
US8879813B1
(en)
|
2013-10-22 |
2014-11-04 |
Eyenuk, Inc. |
Systems and methods for automated interest region detection in retinal images
|
|
PE20191716A1
(es)
*
|
2017-02-08 |
2019-12-05 |
Bristol Myers Squibb Co |
Polipeptidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos
|