JP2012511560A5 - - Google Patents

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Publication number
JP2012511560A5
JP2012511560A5 JP2011540197A JP2011540197A JP2012511560A5 JP 2012511560 A5 JP2012511560 A5 JP 2012511560A5 JP 2011540197 A JP2011540197 A JP 2011540197A JP 2011540197 A JP2011540197 A JP 2011540197A JP 2012511560 A5 JP2012511560 A5 JP 2012511560A5
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JP
Japan
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compound
bis
formula
treatment
saturated
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JP2011540197A
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English (en)
Japanese (ja)
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JP2012511560A (ja
JP5814125B2 (ja
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Priority claimed from PCT/GB2009/002865 external-priority patent/WO2010067078A2/en
Publication of JP2012511560A publication Critical patent/JP2012511560A/ja
Publication of JP2012511560A5 publication Critical patent/JP2012511560A5/ja
Application granted granted Critical
Publication of JP5814125B2 publication Critical patent/JP5814125B2/ja
Expired - Fee Related legal-status Critical Current
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JP2011540197A 2008-12-10 2009-12-10 3,6−二置換キサンチリウム塩 Expired - Fee Related JP5814125B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12128808P 2008-12-10 2008-12-10
US61/121,288 2008-12-10
PCT/GB2009/002865 WO2010067078A2 (en) 2008-12-10 2009-12-10 3,6-disubstituted xanthylium salts as medicaments

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015042371A Division JP6148270B2 (ja) 2008-12-10 2015-03-04 3,6−二置換キサンチリウム塩

Publications (3)

Publication Number Publication Date
JP2012511560A JP2012511560A (ja) 2012-05-24
JP2012511560A5 true JP2012511560A5 (enExample) 2013-01-31
JP5814125B2 JP5814125B2 (ja) 2015-11-17

Family

ID=41716277

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011540197A Expired - Fee Related JP5814125B2 (ja) 2008-12-10 2009-12-10 3,6−二置換キサンチリウム塩
JP2015042371A Active JP6148270B2 (ja) 2008-12-10 2015-03-04 3,6−二置換キサンチリウム塩
JP2016159662A Pending JP2017019823A (ja) 2008-12-10 2016-08-16 3,6−二置換キサンチリウム塩

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015042371A Active JP6148270B2 (ja) 2008-12-10 2015-03-04 3,6−二置換キサンチリウム塩
JP2016159662A Pending JP2017019823A (ja) 2008-12-10 2016-08-16 3,6−二置換キサンチリウム塩

Country Status (17)

Country Link
US (3) US8658665B2 (enExample)
EP (4) EP3689346B1 (enExample)
JP (3) JP5814125B2 (enExample)
KR (6) KR102508594B1 (enExample)
CN (2) CN104367571A (enExample)
AU (1) AU2009326173B2 (enExample)
BR (3) BRPI0922326B8 (enExample)
CA (3) CA2745203C (enExample)
DK (3) DK2373660T3 (enExample)
ES (3) ES2799892T3 (enExample)
FI (1) FI3689346T3 (enExample)
HK (1) HK1207319A1 (enExample)
MX (3) MX367131B (enExample)
PL (3) PL3112358T3 (enExample)
PT (3) PT3689346T (enExample)
SI (3) SI3689346T1 (enExample)
WO (1) WO2010067078A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3689346B1 (en) 2008-12-10 2024-01-24 WisTa Laboratories Ltd. 3,6-disubstituted xanthylium salts for treating tauopathies
US8785434B2 (en) 2010-04-30 2014-07-22 Prosetta Antiviral Inc. Antiviral compounds
US8828986B2 (en) 2011-04-20 2014-09-09 Prosetta Antiviral Inc. Antiviral compounds
US9084720B2 (en) * 2013-05-07 2015-07-21 BioBlast Pharma Ltd. Compositions and methods for treating oculopharyngeal muscular dystrophy
WO2014181333A2 (en) 2013-05-07 2014-11-13 Bio Blast Pharma Ltd. Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
KR102229645B1 (ko) 2013-06-07 2021-03-18 가부시키가이샤 아데카 착색 감광성 조성물 및 신규 화합물
WO2016184911A1 (en) * 2015-05-18 2016-11-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of the neuropathology of patients suffering from myotonic dystrophy type 1 (dm1)
CN106009761B (zh) * 2016-05-31 2017-08-15 延边大学 一种派洛宁染料的制备方法
EP3357928B1 (en) 2017-02-03 2021-01-06 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Novel dyes with phosphinic acid, phosphinate, phosphonate and phosphonamidate substituents as auxochromic groups and methods for preparing the same
CN108570032B (zh) * 2017-03-09 2021-04-02 华东理工大学 新型罗丹明染料及其在抗致病菌中的应用
WO2020019289A1 (zh) * 2018-07-27 2020-01-30 华东理工大学 新型罗丹明染料及其在抗致病菌中的应用
KR102496845B1 (ko) * 2018-08-08 2023-02-08 서울대학교산학협력단 진단 지표로서 베타-아밀로이드 수준과 함께 혈장 타우 수준을 사용하는 알츠하이머병의 진단 및 치료 방법
CA3150309A1 (en) 2019-10-01 2021-04-08 Seelos Therapeutics, Inc. Trehalose formulations and uses thereof
CA3164184A1 (en) 2020-01-24 2021-07-29 Oregon Health & Science University Oxazine-based fluorophore compounds for nerve-specific imaging
GB2703562A (en) * 2024-12-13 2026-08-05 Wista Lab Ltd Fused heterocyclic compounds and uses thereof

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE65282C (de) A. Leonhardt & Co. in Mühlheim i. H Verfahren zur Ueberführung von Rhodaminfarbstoffen in gelbere Farbstoffe durch Oxydationsmittel
US2397423A (en) 1943-03-17 1946-03-26 Us Rubber Co Parasiticidal preparations
US3284205A (en) * 1963-09-17 1966-11-08 Horizons Inc Benzotriazole and heterocyclic ketimide activators for leuco compounds
US3620748A (en) 1966-01-07 1971-11-16 Horizons Research Inc N-vinyl amine/halogen liberating composition sensitized with 9-vinyl carbazoles or polyacenes, or transannular peroxides of polyacenes
DE1915910A1 (de) * 1969-03-28 1970-10-08 Agfa Gevaert Ag Spektral sensibilisierte photographische Direktpositiv-Emulsion
BE756085A (de) 1969-09-12 1971-03-15 Agfa Gevaert Nv Spectraal gesensibiliseerd fotografisch materiaal
US3873940A (en) * 1971-08-09 1975-03-25 Eastman Kodak Co Laser media containing rigidized dyes
US3932415A (en) * 1972-04-17 1976-01-13 Eastman Kodak Company Pyrylium dyes having a fused rigidized nitrogen-containing ring
BE806408A (nl) 1973-10-23 1974-04-23 Oce Van Der Grinten Nv Tonerpoeder voor het ontwikkelen van elektrostatische beelden
JPS52113738A (en) * 1976-03-19 1977-09-24 Canon Inc Electrostatically developing toner
US4065315A (en) 1976-04-26 1977-12-27 Dynachem Corporation Phototropic dye system and photosensitive compositions containing the same
CS193815B1 (en) 1977-03-28 1979-11-30 Jaroslav Senkyr Fluid membranes in function of the ionto-convertors for the nitrate iont selective electrode
DE3322945A1 (de) 1983-06-25 1985-01-03 Bayer Ag, 5090 Leverkusen Laserfarbstoffe
JPS61165307A (ja) * 1985-01-18 1986-07-26 Asahi Chem Ind Co Ltd 3,6−ジアミノキサンテン誘導体を含有する除草剤
JPS62278571A (ja) 1986-05-27 1987-12-03 Ricoh Co Ltd 静電荷像現像用トナ−
JPS63131148A (ja) 1986-11-21 1988-06-03 Ricoh Co Ltd 静電潜像現像用乾式トナ−
DE3714288A1 (de) 1987-04-29 1988-11-10 Bayer Ag Fanalpigmente ringgeschlossener indamin- und diphenylmethanfarbstoffe enthaltende trockentoner
DE3714289A1 (de) * 1987-04-29 1988-11-10 Bayer Ag Fanalpigmente ringgeschlossener indamin- und diphenylmethanfarbstoffe enthaltende trockentoner
AU3008289A (en) 1988-02-22 1989-08-24 Eastman Kodak Company Novel thiorhodamines and a novel method of preparation
JPH01229003A (ja) 1988-03-09 1989-09-12 Fuji Photo Film Co Ltd 光重合性組成物
DE4326460A1 (de) 1992-08-10 1994-02-17 Ciba Geigy Verfahren zum Färben von Materialien auf der Basis von Hydroxyapatit
JPH06208191A (ja) 1992-11-18 1994-07-26 Oriental Photo Ind Co Ltd 乾式銀塩感光体及びこの乾式銀塩感光体を用いた画像形成方法
EP0599184A3 (en) * 1992-11-18 1996-12-04 Canon Kk Dry process silver salt photosensitive material and image forming method making use of this dry process silver salt photosensitive material.
JPH06236000A (ja) 1993-02-12 1994-08-23 Showa Denko Kk 光消色性記録材料
JPH0785972A (ja) 1993-09-20 1995-03-31 Toshiba Corp 有機el素子
US5459268A (en) 1993-10-25 1995-10-17 Molecular Probes, Inc. Xanthylium dyes that are well retained in mitochondria
GB9506197D0 (en) * 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
JPH08324117A (ja) 1995-05-30 1996-12-10 Ricoh Co Ltd 光情報記録媒体
EP0805441B1 (de) * 1996-05-03 2003-10-08 Ciba SC Holding AG Optische Speichermedien mit hoher Kapazität, die Xanthenfarbstoffe enthalten
US20030044776A1 (en) 1998-09-25 2003-03-06 James A. Dykens Compositions and methods for identifying agents that alter mitochondrial permeability transition pores
JP3886271B2 (ja) 1998-11-27 2007-02-28 シスメックス株式会社 赤芽球の分類計数用試薬及び分類計数方法
JP2000344684A (ja) 1999-03-26 2000-12-12 Bf Kenkyusho:Kk ピロニンb類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
GB0106953D0 (en) 2001-03-20 2001-05-09 Univ Aberdeen Neufofibrillary labels
JP4647187B2 (ja) * 2001-04-02 2011-03-09 セルメド バイオサイエンシズ インコーポレイテッド ハロゲン化ローダミン誘導体およびその適用
US7166478B2 (en) * 2002-03-12 2007-01-23 Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses
WO2004005389A1 (ja) 2002-07-09 2004-01-15 Orient Chemical Industries, Ltd. 核効果抑制剤、結晶性樹脂組成物及び結晶性樹脂組成物の結晶化制御法
JP2004061947A (ja) * 2002-07-30 2004-02-26 Fuji Photo Film Co Ltd 平版印刷版原版
EP1654326A1 (en) * 2003-08-01 2006-05-10 VersaMatrix A/S Triangulenium fluorescent dyes and polymers comprising such dyes
ATE531767T1 (de) 2003-08-21 2011-11-15 Merck Patent Gmbh Cyanoborat-farbstoffe
WO2005034855A2 (en) * 2003-09-05 2005-04-21 The General Hospital Corporation Photodynamic inactivation of bacterial spores
AU2004294243B2 (en) * 2003-12-05 2011-02-17 Hopital Maisonneuve-Rosemont Immunologic compounds for prevention, protection, prophylaxis or treatment of immunological disorders, infections and cancer
US8029765B2 (en) 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
EP1713457A2 (de) * 2004-02-11 2006-10-25 Max-Delbrück-Centrum Für Molekulare Medizin Neue arzneimittel und diagnostische zusammensetzungen f r be handlung und diagnose von neurodegenerativen erkrankungen und amyloid-krankheiten
CN1594463A (zh) 2004-07-02 2005-03-16 林劲冬 光催化氧化还原降解消色板书墨水及其降解促进剂
WO2006026033A2 (en) 2004-08-02 2006-03-09 The Research Foundation Of State University Of New York Stor Novel chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy
CN101132796A (zh) * 2005-02-17 2008-02-27 独立行政法人科学技术振兴机构 含有吩嗪化合物作为活性成分的药物组合物
CA2607475A1 (en) * 2005-04-22 2006-11-02 Genentech, Inc. Method for treating dementia or alzheimer's disease with a cd20 antibody
FR2889060B1 (fr) 2005-08-01 2009-05-15 Oreal Composition de teinture des fibres keratiniques comprenant un colorant direct amidoxanthenique et procede de teinture l a mettant en oeuvre
KR101341855B1 (ko) * 2005-10-06 2013-12-20 시바 홀딩 인코포레이티드 옥사진 디설파이드 염료
DK2853293T3 (en) * 2006-03-29 2018-01-22 Wista Lab Ltd Thioninium compounds and their use
CN104119294B (zh) * 2006-03-29 2018-10-30 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物的制备方法
FR2915878B1 (fr) 2007-05-07 2009-08-21 Oreal Compositions comprenant des colorants directs xantheniques fluores, procedes de mise en oeuvre et utilisations.
US8247145B2 (en) 2007-09-07 2012-08-21 Konica Minolta Business Technologies, Inc. Magenta toner for developing electrostatic image
WO2009030871A1 (en) 2007-09-07 2009-03-12 Vernalis R & D Ltd Pyrrolopyrimidine derivatives having hsp90 inhibitory activity
WO2010033011A1 (en) * 2008-09-19 2010-03-25 Cancer Research Initiatives Foundation Rosamine derivatives as agents for the treatment of cancer
EP3689346B1 (en) 2008-12-10 2024-01-24 WisTa Laboratories Ltd. 3,6-disubstituted xanthylium salts for treating tauopathies

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