JP2006516643A5 - - Google Patents
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- Publication number
- JP2006516643A5 JP2006516643A5 JP2006503254A JP2006503254A JP2006516643A5 JP 2006516643 A5 JP2006516643 A5 JP 2006516643A5 JP 2006503254 A JP2006503254 A JP 2006503254A JP 2006503254 A JP2006503254 A JP 2006503254A JP 2006516643 A5 JP2006516643 A5 JP 2006516643A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- tianeptine
- group
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/358,034 US6683072B1 (en) | 2003-02-04 | 2003-02-04 | Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia |
| PCT/US2004/002931 WO2004069188A2 (en) | 2003-02-04 | 2004-02-02 | Methods for treatment of ibs and nud |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006516643A JP2006516643A (ja) | 2006-07-06 |
| JP2006516643A5 true JP2006516643A5 (enExample) | 2007-03-15 |
Family
ID=30115458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006503254A Pending JP2006516643A (ja) | 2003-02-04 | 2004-02-02 | 過敏性大腸症候群及び神経性胃炎の治療用組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6683072B1 (enExample) |
| EP (1) | EP1594509B1 (enExample) |
| JP (1) | JP2006516643A (enExample) |
| AT (1) | ATE476982T1 (enExample) |
| CA (1) | CA2515048A1 (enExample) |
| DE (1) | DE602004028574D1 (enExample) |
| WO (1) | WO2004069188A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05005895A (es) * | 2002-12-03 | 2006-02-08 | Vela Pharmaceuticals Inc | Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma. |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| FR2881350B1 (fr) * | 2005-02-02 | 2007-04-06 | Merck Generiques Soc En Comman | Nouvelle forme galenique orale de la tianeptine |
| US7541355B2 (en) * | 2005-05-23 | 2009-06-02 | Vela Acquisition Corporation | Conversion process for 2,3-benzodiazepine enantiomers |
| EP1752143A1 (en) * | 2005-08-08 | 2007-02-14 | NewThera | Novel uses for drugs targeting glutamine synthetase |
| EP2137157A4 (en) * | 2007-03-05 | 2010-12-15 | Transform Pharmaceuticals Inc | POLYMORPHES OF 7 - [(3-CHLORO-6,11-DIHYDRO-6-METHYLDIBENZO [C, F] [1,2] THIAZEPIN-11-YL) AMNO] HEPTANIC ACID S, S-DIOXIDE AND PROCESS FOR THEIR PREPARATION AND THEIR USE |
| DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EP2328910B1 (en) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US8198268B2 (en) * | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
| CN102977053B (zh) * | 2012-11-30 | 2015-04-15 | 山东诚创医药技术开发有限公司 | 一种噻奈普汀钠杂质d的制备方法 |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| GB201517133D0 (en) * | 2015-09-28 | 2015-11-11 | Numedicus Ltd | New pharmaceutical use |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL138423C (enExample) | 1966-07-14 | |||
| GB1269551A (en) | 1969-03-27 | 1972-04-06 | Science Union & Cie | New tricyclic derivatives and process for their manufacture |
| US3821249A (en) | 1970-03-13 | 1974-06-28 | En Nom Collectif Science Union | Dibenzothiazefin derivatives |
| US3758528A (en) | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
| CH629667A5 (fr) * | 1978-03-28 | 1982-05-14 | Science Union & Cie | Composition pharmaceutique agissant sur la motricite gastro-intestinale. |
| FR2480283A1 (fr) | 1980-04-10 | 1981-10-16 | Science Union & Cie | Nouveaux derives tricycliques, leurs procedes de preparation et leur utilisation comme medicament |
| FR2594827B1 (fr) | 1986-02-21 | 1988-05-20 | Adir | Nouveau derive tricyclique denomme acide ((chloro-3 methyl-6 dioxo-5,5 dihydro-6, 11 dibenzo (c,f) thiazepine (1,2) yl-11 amino)-5 pentazoique, son procede de preparation et les compositions pharmaceutiques qui le contiennent |
| FR2747921B1 (fr) | 1996-04-24 | 1998-10-30 | Adir | Comprime matriciel permettant la liberation prolongee du sel de sodium de tianeptine apres administration par voie orale |
| US6150376A (en) * | 1998-08-05 | 2000-11-21 | Georgetown University | Bi- and tri-cyclic aza compounds and their uses |
| FR2807039A1 (fr) * | 2000-03-31 | 2001-10-05 | Adir | NOUVEAU PROCEDE DE PREPARATION DE LA 11-AMINO-3-CHLORO-6,11- DIHYDRO-5,5-DIOXO-6-METHYL-DIBENZO[c,f][1,2]-THIAZEPINE ET APPLICATION A LA SYNTHESE DE LA TIANEPTINE |
-
2003
- 2003-02-04 US US10/358,034 patent/US6683072B1/en not_active Expired - Lifetime
-
2004
- 2004-02-02 EP EP04707447A patent/EP1594509B1/en not_active Expired - Lifetime
- 2004-02-02 WO PCT/US2004/002931 patent/WO2004069188A2/en not_active Ceased
- 2004-02-02 AT AT04707447T patent/ATE476982T1/de not_active IP Right Cessation
- 2004-02-02 CA CA002515048A patent/CA2515048A1/en not_active Abandoned
- 2004-02-02 JP JP2006503254A patent/JP2006516643A/ja active Pending
- 2004-02-02 DE DE602004028574T patent/DE602004028574D1/de not_active Expired - Lifetime
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