JP2011116780A5 - - Google Patents
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- JP2011116780A5 JP2011116780A5 JP2011049671A JP2011049671A JP2011116780A5 JP 2011116780 A5 JP2011116780 A5 JP 2011116780A5 JP 2011049671 A JP2011049671 A JP 2011049671A JP 2011049671 A JP2011049671 A JP 2011049671A JP 2011116780 A5 JP2011116780 A5 JP 2011116780A5
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- Prior art keywords
- compound
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- hydrochloride
- Prior art date
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- 0 *C(C*CC(*)(*)c1c(*)c(*)c(*)c(*)c1)O Chemical compound *C(C*CC(*)(*)c1c(*)c(*)c(*)c(*)c1)O 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47928003P | 2003-06-17 | 2003-06-17 | |
| US60/479,280 | 2003-06-17 | ||
| US51296703P | 2003-10-21 | 2003-10-21 | |
| US60/512,967 | 2003-10-21 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006517336A Division JP4920409B2 (ja) | 2003-06-17 | 2004-06-16 | 3−ベンズアゼピンを調製する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012049640A Division JP5667593B2 (ja) | 2003-06-17 | 2012-03-06 | 3−ベンズアゼピンを調製する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011116780A JP2011116780A (ja) | 2011-06-16 |
| JP2011116780A5 true JP2011116780A5 (enExample) | 2012-04-26 |
| JP5421311B2 JP5421311B2 (ja) | 2014-02-19 |
Family
ID=34221229
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006517336A Expired - Fee Related JP4920409B2 (ja) | 2003-06-17 | 2004-06-16 | 3−ベンズアゼピンを調製する方法 |
| JP2011049671A Expired - Fee Related JP5421311B2 (ja) | 2003-06-17 | 2011-03-07 | 3−ベンズアゼピンを調製する方法 |
| JP2012049640A Expired - Fee Related JP5667593B2 (ja) | 2003-06-17 | 2012-03-06 | 3−ベンズアゼピンを調製する方法 |
| JP2014090162A Withdrawn JP2014133771A (ja) | 2003-06-17 | 2014-04-24 | 3−ベンズアゼピンを調製する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006517336A Expired - Fee Related JP4920409B2 (ja) | 2003-06-17 | 2004-06-16 | 3−ベンズアゼピンを調製する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012049640A Expired - Fee Related JP5667593B2 (ja) | 2003-06-17 | 2012-03-06 | 3−ベンズアゼピンを調製する方法 |
| JP2014090162A Withdrawn JP2014133771A (ja) | 2003-06-17 | 2014-04-24 | 3−ベンズアゼピンを調製する方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US8367657B2 (enExample) |
| EP (4) | EP1636191A2 (enExample) |
| JP (4) | JP4920409B2 (enExample) |
| KR (1) | KR101215107B1 (enExample) |
| AU (1) | AU2004267016B2 (enExample) |
| BR (1) | BRPI0411613B8 (enExample) |
| CA (1) | CA2529401C (enExample) |
| CY (1) | CY1117619T1 (enExample) |
| DK (1) | DK2332921T3 (enExample) |
| EA (1) | EA016485B1 (enExample) |
| ES (1) | ES2571220T3 (enExample) |
| HU (1) | HUE028976T2 (enExample) |
| IL (1) | IL172331A (enExample) |
| MX (1) | MXPA05013364A (enExample) |
| PL (1) | PL2332921T3 (enExample) |
| SI (1) | SI2332921T1 (enExample) |
| WO (1) | WO2005019179A2 (enExample) |
Families Citing this family (45)
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| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
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| SI2332921T1 (sl) | 2003-06-17 | 2016-06-30 | Arena Pharmaceuticals, Inc. | 8-kloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzazapin hidroklorid |
| CA2589988C (en) * | 2004-12-21 | 2017-02-14 | Arena Pharmaceuticals, Inc. | Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride |
| PT1833473E (pt) | 2004-12-23 | 2009-12-17 | Arena Pharm Inc | Composições de modulador de receptor 5ht2c e métodos de utilização |
| BRPI0615048A2 (pt) | 2005-09-01 | 2010-03-30 | Lilly Co Eli | composto, composição farmacêutica, e, uso de um composto |
| EP1924560B1 (en) | 2005-09-01 | 2009-08-05 | Eli Lilly And Company | 6-substituted- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists |
| BRPI0615033A2 (pt) | 2005-09-01 | 2011-04-26 | Lilly Co Eli | composto, composição farmacêutica, e, uso de um composto |
| JP5249031B2 (ja) | 2005-09-01 | 2013-07-31 | イーライ リリー アンド カンパニー | 5−HT2C受容体アゴニストとしての6−N結合型へテロ環置換された2,3,4,5−テトラヒドロ−1H−ベンゾ[d]アゼピン |
| MX2008009178A (es) | 2006-01-19 | 2008-12-05 | Athersys Inc | Tiofenil y pirrolil acepinas como ligandos del receptor de serotonina 5-ht2c y sus usos. |
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| EP2018863B9 (en) | 2006-05-16 | 2015-02-18 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and use thereof |
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| EP2789338A3 (en) | 2007-11-15 | 2015-01-14 | Takeda Pharmaceutical Company Limited | Condensed pyridine derivate and use thereof |
| JP5491421B2 (ja) * | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 5−ht2cアゴニストである(r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンゾアゼピンに関連する中間体の調製のためのプロセス |
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| WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| MX2013002422A (es) * | 2010-09-01 | 2013-05-17 | Arena Pharm Inc | Sales de lorcaserina con acidos opticamente activos. |
| WO2012030957A2 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
| US20130267500A1 (en) | 2010-09-01 | 2013-10-10 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
| SG188363A1 (en) * | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Fast-dissolve dosage forms of 5-ht2c agonists |
| KR20180118801A (ko) | 2010-09-01 | 2018-10-31 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 체중 관리에 유용한 5-ht2c 작동제의 변형-방출 투여 형태 |
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| WO2014058441A1 (en) | 2012-10-09 | 2014-04-17 | Arena Pharmaceuticals, Inc. | Method of weight management |
| WO2014060575A2 (en) | 2012-10-19 | 2014-04-24 | Medichem S.A. | Process for the enantioselective synthesis of a tetrahydrobenzazepine compound |
| EA026397B1 (ru) | 2012-12-21 | 2017-04-28 | ЭйБиТи ХОЛДИНГ КОМПАНИ | Бензазепины в качестве лигандов серотониновых 5-ht-рецепторов и их применение |
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| EP2999692A1 (en) | 2013-05-20 | 2016-03-30 | LEK Pharmaceuticals d.d. | Novel synthetic processes to 8-chloro-3-benzo[d]azepine via friedel-crafts alkylation of olefin |
| CN103333111A (zh) * | 2013-06-14 | 2013-10-02 | 苏州汇和药业有限公司 | 氯卡色林盐酸盐的制备方法 |
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| EP2868656A1 (en) | 2013-11-05 | 2015-05-06 | LEK Pharmaceuticals d.d. | Stabilized amorphous lorcaserin hydrochloride |
| WO2015096119A1 (zh) * | 2013-12-27 | 2015-07-02 | 杭州普晒医药科技有限公司 | 氯卡色林盐及其晶体、其制备方法和用途 |
| EP2924024A3 (en) | 2014-03-21 | 2016-01-20 | Medichem, S.A. | Solid forms of lorcaserin hydrochloride |
| CN105228986B (zh) | 2014-04-21 | 2017-11-07 | 杭州普晒医药科技有限公司 | 一种氯卡色林共晶及其制备方法、药物组合物和用途 |
| WO2015170346A1 (en) | 2014-05-09 | 2015-11-12 | Council Of Scientific & Industrial Research | A process for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine its enantiomers |
| WO2016057931A1 (en) | 2014-10-10 | 2016-04-14 | The Research Foundation For The State University Of New York | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration |
| WO2016069875A1 (en) | 2014-10-30 | 2016-05-06 | Arena Pharmaceuticals, Inc. | Compositions and methods for ceasing tobacco smoking |
| EP3210975A1 (en) | 2016-02-24 | 2017-08-30 | Enantia, S.L. | Cocrystals of lorcaserin |
| US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
| WO2022165382A1 (en) * | 2021-01-29 | 2022-08-04 | Neurawell Therapeutics | Phenylethylidenehydrazine combination therapies |
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-
2004
- 2004-06-16 SI SI200432322A patent/SI2332921T1/sl unknown
- 2004-06-16 EP EP04801895A patent/EP1636191A2/en not_active Withdrawn
- 2004-06-16 CA CA2529401A patent/CA2529401C/en not_active Expired - Lifetime
- 2004-06-16 BR BRPI0411613A patent/BRPI0411613B8/pt not_active IP Right Cessation
- 2004-06-16 WO PCT/US2004/019279 patent/WO2005019179A2/en not_active Ceased
- 2004-06-16 AU AU2004267016A patent/AU2004267016B2/en not_active Expired
- 2004-06-16 EP EP10010301.9A patent/EP2332921B1/en not_active Expired - Lifetime
- 2004-06-16 EP EP10010295A patent/EP2332919A3/en not_active Withdrawn
- 2004-06-16 ES ES10010301T patent/ES2571220T3/es not_active Expired - Lifetime
- 2004-06-16 US US10/560,953 patent/US8367657B2/en not_active Expired - Fee Related
- 2004-06-16 HU HUE10010301A patent/HUE028976T2/en unknown
- 2004-06-16 PL PL10010301T patent/PL2332921T3/pl unknown
- 2004-06-16 JP JP2006517336A patent/JP4920409B2/ja not_active Expired - Fee Related
- 2004-06-16 MX MXPA05013364A patent/MXPA05013364A/es active IP Right Grant
- 2004-06-16 EA EA200600049A patent/EA016485B1/ru not_active IP Right Cessation
- 2004-06-16 EP EP09012098.1A patent/EP2189448B1/en not_active Expired - Lifetime
- 2004-06-16 DK DK10010301.9T patent/DK2332921T3/en active
-
2005
- 2005-12-02 IL IL172331A patent/IL172331A/en active IP Right Grant
- 2005-12-16 KR KR1020057024265A patent/KR101215107B1/ko not_active Expired - Lifetime
-
2011
- 2011-03-07 JP JP2011049671A patent/JP5421311B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-06 JP JP2012049640A patent/JP5667593B2/ja not_active Expired - Fee Related
- 2012-09-14 US US13/619,773 patent/US8946207B2/en not_active Expired - Lifetime
- 2012-09-14 US US13/619,788 patent/US9102627B2/en not_active Expired - Lifetime
-
2014
- 2014-04-24 JP JP2014090162A patent/JP2014133771A/ja not_active Withdrawn
-
2015
- 2015-07-27 US US14/810,063 patent/US20160185729A1/en not_active Abandoned
-
2016
- 2016-05-18 CY CY20161100427T patent/CY1117619T1/el unknown
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