|
JPS5531159A
(en)
|
1978-08-26 |
1980-03-05 |
Sumitomo Metal Ind Ltd |
Manufacture of high strength cold rolled steel plate for press working
|
|
US4399216A
(en)
*
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
*
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
|
US4504586A
(en)
*
|
1983-02-03 |
1985-03-12 |
Amgen |
Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
|
|
US4740461A
(en)
|
1983-12-27 |
1988-04-26 |
Genetics Institute, Inc. |
Vectors and methods for transformation of eucaryotic cells
|
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US6117422A
(en)
*
|
1985-02-05 |
2000-09-12 |
Chiron Corporation |
N∇2-CSF-1(long form) and carboxy truncated fragments thereof
|
|
AU594045B2
(en)
*
|
1985-02-05 |
1990-03-01 |
Chiron Corporation |
Recombinant colony stimulating factor-1
|
|
US5573930A
(en)
*
|
1985-02-05 |
1996-11-12 |
Cetus Oncology Corporation |
DNA encoding various forms of colony stimulating factor-1
|
|
US5837229A
(en)
|
1985-02-05 |
1998-11-17 |
Chiron Corporation |
Uses of recombinant colony stimulating factor-1
|
|
US5792450A
(en)
*
|
1985-02-05 |
1998-08-11 |
Chiron Corporation |
Purified human CSF-1
|
|
US4847201A
(en)
*
|
1985-02-05 |
1989-07-11 |
Cetus Corporation |
DNA encoding for CSF-1 and accompanying recombinant systems
|
|
DE3668186D1
(de)
|
1985-04-01 |
1990-02-15 |
Celltech Ltd |
Transformierte myeloma-zell-linie und dieselbe verwendendes verfahren zur expression eines gens, das ein eukaryontisches polypeptid kodiert.
|
|
US4968615A
(en)
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
HU212277B
(en)
*
|
1986-05-06 |
1996-04-29 |
Genetics Inst |
Process for producing m-csf
|
|
US4868119A
(en)
*
|
1986-12-11 |
1989-09-19 |
Genetics Institute, Inc. |
Hematopoietic growth factors
|
|
US4959455A
(en)
*
|
1986-07-14 |
1990-09-25 |
Genetics Institute, Inc. |
Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
|
|
GB8624899D0
(en)
|
1986-10-17 |
1986-11-19 |
Sandoz Ltd |
Monoclonal antibodies
|
|
US4912040A
(en)
|
1986-11-14 |
1990-03-27 |
Genetics Institute, Inc. |
Eucaryotic expression system
|
|
CA1339757C
(en)
*
|
1987-04-16 |
1998-03-17 |
Robert F. Halenbeck |
Production of purified biologically active, bacterially produced recombinant human csf-1
|
|
US4929700A
(en)
*
|
1987-04-16 |
1990-05-29 |
Cetus Corporation |
Production of purified, biologically active, bacterially produced recombinant human CSF-1
|
|
US5750172A
(en)
|
1987-06-23 |
1998-05-12 |
Pharming B.V. |
Transgenic non human mammal milk
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
US4929455A
(en)
*
|
1988-07-07 |
1990-05-29 |
Mallinckrodt, Inc. |
Flour-based pot pie crusts with improved texture
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
GB8823869D0
(en)
*
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
ES2091816T3
(es)
*
|
1989-02-10 |
1996-11-16 |
Cetus Oncology Corp |
Anticuerpos monoclonales del factor estimulador de colonias de macrofagos (m-csf) que reconocen un epitope conformacional neutralizante.
|
|
CA2062975A1
(en)
|
1989-07-14 |
1991-01-15 |
Gail F. Seelig |
Antagonists of gm-csf derived from the carboxyl terminus
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
US5633076A
(en)
*
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
JPH05503098A
(ja)
|
1989-12-15 |
1993-05-27 |
カイロン コーポレイション |
セプシスの処理のためのサイトカイン抗体
|
|
US6075181A
(en)
*
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
ES2284161T3
(es)
*
|
1990-01-12 |
2007-11-01 |
Amgen Fremont Inc. |
Generacion de anticuerpos xenogenicos.
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5151510A
(en)
*
|
1990-04-20 |
1992-09-29 |
Applied Biosystems, Inc. |
Method of synethesizing sulfurized oligonucleotide analogs
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
CA2109602C
(en)
|
1990-07-10 |
2002-10-01 |
Gregory P. Winter |
Methods for producing members of specific binding pairs
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
AU8507191A
(en)
|
1990-08-29 |
1992-03-30 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69133557D1
(de)
|
1990-08-29 |
2007-03-15 |
Pharming Intellectual Pty Bv |
Homologe rekombination in säugetier-zellen
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6255458B1
(en)
*
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5814318A
(en)
*
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US7084260B1
(en)
*
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
US7041871B1
(en)
*
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5789650A
(en)
*
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
ES2113940T3
(es)
|
1990-12-03 |
1998-05-16 |
Genentech Inc |
Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
|
|
CA2060741A1
(en)
|
1991-02-11 |
1992-08-12 |
Robert S. Greenfield |
Gm-csf inhibiting oligopeptides
|
|
DE69233769D1
(de)
|
1991-03-01 |
2009-09-24 |
Dyax Corp |
Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon
|
|
AU662148B2
(en)
|
1991-04-10 |
1995-08-24 |
Scripps Research Institute, The |
Heterodimeric receptor libraries using phagemids
|
|
DE4122599C2
(de)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid zum Screenen von Antikörpern
|
|
WO1993004169A1
(en)
*
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
|
EP0605522B1
(en)
|
1991-09-23 |
1999-06-23 |
Medical Research Council |
Methods for the production of humanized antibodies
|
|
JPH0595794A
(ja)
*
|
1991-10-04 |
1993-04-20 |
Otsuka Pharmaceut Co Ltd |
ヒトｍ−ｃｓｆ抗体及びヒトｍ−ｃｓｆの測定法
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
AU668374B2
(en)
|
1991-12-10 |
1996-05-02 |
Dana-Farber Cancer Institute |
Reactive neutralizing human anti-GP120 recombinant antibody, DNA coding the same and use thereof
|
|
JPH067189A
(ja)
|
1991-12-17 |
1994-01-18 |
Morinaga Milk Ind Co Ltd |
ヒトＭ−ＣＳＦ β型ダイマ−に特異性を有するモノクロ− ナル抗体と、この抗体を産生するハイブリドーマ、お よびこの抗体の利用
|
|
WO1993016185A2
(en)
|
1992-02-06 |
1993-08-19 |
Creative Biomolecules, Inc. |
Biosynthetic binding protein for cancer marker
|
|
JPH0595794U
(ja)
|
1992-06-04 |
1993-12-27 |
智子 中嶋 |
ものさし目盛り付ボールペン
|
|
US5866114A
(en)
*
|
1992-06-09 |
1999-02-02 |
Chiron Corporation |
Crystallization of M-CSFα
|
|
ES2301158T3
(es)
|
1992-07-24 |
2008-06-16 |
Amgen Fremont Inc. |
Produccion de anticuerpos xenogenicos.
|
|
JP3714683B2
(ja)
*
|
1992-07-30 |
2005-11-09 |
生化学工業株式会社 |
抗リウマチ剤
|
|
US6177401B1
(en)
|
1992-11-13 |
2001-01-23 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften |
Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
|
|
JPH06194367A
(ja)
|
1992-12-25 |
1994-07-15 |
Morinaga Milk Ind Co Ltd |
リウマチ疾患の診断方法
|
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
|
ES2146648T3
(es)
*
|
1993-03-09 |
2000-08-16 |
Genzyme Corp |
Procedimiento de aislamiento de proteinas de la leche.
|
|
JPH06319584A
(ja)
|
1993-05-07 |
1994-11-22 |
Morinaga Milk Ind Co Ltd |
抗ｍ−ｃｓｆモノクロ−ナル抗体と、この抗体を産生 するハイブリド−マ
|
|
US5827690A
(en)
*
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
IL112248A0
(en)
|
1994-01-25 |
1995-03-30 |
Warner Lambert Co |
Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
|
|
WO1995029690A1
(en)
*
|
1994-04-29 |
1995-11-09 |
The Trustees Of The University Of Pennsylvania |
Biologically active peptides and methods of identifying the same
|
|
US5643763A
(en)
*
|
1994-11-04 |
1997-07-01 |
Genpharm International, Inc. |
Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating
|
|
US6046037A
(en)
|
1994-12-30 |
2000-04-04 |
Hiatt; Andrew C. |
Method for producing immunoglobulins containing protection proteins in plants and their use
|
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US6130364A
(en)
*
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US6091001A
(en)
*
|
1995-03-29 |
2000-07-18 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
JP3053222B2
(ja)
|
1995-04-20 |
2000-06-19 |
ファイザー・インコーポレーテッド |
Ｍｍｐおよびｔｎｆ抑制剤としてのアリールスルホニルヒドロキサム酸誘導体
|
|
AU705616B2
(en)
|
1995-04-21 |
1999-05-27 |
Cell Genesys, Inc. |
Generation of large genomic DNA deletions
|
|
EP0822830B1
(en)
|
1995-04-27 |
2008-04-02 |
Amgen Fremont Inc. |
Human anti-IL-8 antibodies, derived from immunized xenomice
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
GB9520822D0
(en)
|
1995-10-11 |
1995-12-13 |
Wellcome Found |
Therapeutically active compounds
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
ATE225343T1
(de)
|
1995-12-20 |
2002-10-15 |
Hoffmann La Roche |
Matrix-metalloprotease inhibitoren
|
|
ES2169355T3
(es)
|
1996-03-05 |
2002-07-01 |
Astrazeneca Ab |
Derivados de 4-anilinoquinazolina.
|
|
US5714352A
(en)
*
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
US5994619A
(en)
*
|
1996-04-01 |
1999-11-30 |
University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus |
Production of chimeric bovine or porcine animals using cultured inner cell mass cells
|
|
EP0818442A3
(en)
|
1996-07-12 |
1998-12-30 |
Pfizer Inc. |
Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor
|
|
DE69716916T2
(de)
|
1996-07-13 |
2003-07-03 |
Glaxo Group Ltd., Greenford |
Kondensierte heterozyklische verbindungen als protein kinase inhibitoren
|
|
EA199900021A1
(ru)
|
1996-07-13 |
1999-08-26 |
Глаксо, Груп Лимитед |
Бициклические гетероароматические соединения в качестве ингибиторов протеинтирозинкиназы
|
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
|
CA2260898C
(en)
|
1996-07-18 |
2002-05-14 |
Pfizer Limited |
Phosphinate based inhibitors of matrix metalloproteases
|
|
PL331895A1
(en)
|
1996-08-23 |
1999-08-16 |
Pfizer |
Arylosulphonylamino derivatives of hydroxamic acid
|
|
ID18494A
(id)
|
1996-10-02 |
1998-04-16 |
Novartis Ag |
Turunan pirazola leburan dan proses pembuatannya
|
|
US6255455B1
(en)
*
|
1996-10-11 |
2001-07-03 |
The Trustees Of The University Of Pennsylvania |
Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
ATE549918T1
(de)
*
|
1996-12-03 |
2012-04-15 |
Amgen Fremont Inc |
Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden
|
|
DE69730151T2
(de)
|
1997-01-06 |
2005-08-04 |
Pfizer Inc. |
Cyclische sulfonderivate
|
|
AU721748B2
(en)
|
1997-02-03 |
2000-07-13 |
Pfizer Products Inc. |
Arylsulfonylamino hydroxamic acid derivatives
|
|
CA2279863A1
(en)
|
1997-02-07 |
1998-08-13 |
Pfizer Inc. |
N-hydroxy-beta-sulfonyl-propionamide derivatives and their use as inhibitors of matrix metalloproteinases
|
|
WO1998034918A1
(en)
|
1997-02-11 |
1998-08-13 |
Pfizer Inc. |
Arylsulfonyl hydroxamic acid derivatives
|
|
DE69828154T2
(de)
|
1997-03-12 |
2005-06-23 |
Smithkline Beecham Corp. |
Anti-alphavbeta3 humanizierte monoklonale antikörper
|
|
WO1998046644A1
(fr)
|
1997-04-15 |
1998-10-22 |
Snow Brand Milk Products Co., Ltd. |
Nouvelle proteine et methode de production associee
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
CA2289102A1
(en)
|
1997-05-07 |
1998-11-12 |
Sugen, Inc. |
2-indolinone derivatives as modulators of protein kinase activity
|
|
WO1998052976A1
(en)
|
1997-05-21 |
1998-11-26 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
JP2002501532A
(ja)
|
1997-05-30 |
2002-01-15 |
メルク エンド カンパニー インコーポレーテッド |
新規血管形成阻害薬
|
|
ID23668A
(id)
|
1997-08-08 |
2000-05-11 |
Pfizer Prod Inc |
Turunan asam ariloksiarilsulfonilamino hidroksamat
|
|
ATE368665T1
(de)
|
1997-08-22 |
2007-08-15 |
Astrazeneca Ab |
Oxindolylchinazolinderivate als angiogenesehemmer
|
|
JP2001518470A
(ja)
|
1997-09-26 |
2001-10-16 |
メルク エンド カムパニー インコーポレーテッド |
新規な血管形成阻害剤
|
|
WO1999024440A1
(en)
|
1997-11-11 |
1999-05-20 |
Pfizer Products Inc. |
Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
|
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
|
GB9800575D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
|
AU2978899A
(en)
|
1998-03-03 |
1999-09-20 |
Abgenix, Inc. |
Cd147 binding molecules as therapeutics
|
|
JP4462654B2
(ja)
|
1998-03-26 |
2010-05-12 |
ソニー株式会社 |
映像素材選択装置及び映像素材選択方法
|
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
|
IL139934A0
(en)
|
1998-05-29 |
2002-02-10 |
Sugen Inc |
Pyrrole substituted 2-indolinone derivatives and pharmaceutical compositions containing the same
|
|
UA60365C2
(uk)
|
1998-06-04 |
2003-10-15 |
Пфайзер Продактс Інк. |
Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
|
|
AUPP525198A0
(en)
*
|
1998-08-13 |
1998-09-03 |
Medvet Science Pty. Ltd. |
Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
|
|
EP1105427A2
(en)
|
1998-08-17 |
2001-06-13 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
|
DK1004578T3
(da)
|
1998-11-05 |
2004-06-28 |
Pfizer Prod Inc |
5-oxo-pyrrolidin-2-carboxylsyrehydroxamidderivater
|
|
EP1051432B1
(en)
|
1998-12-08 |
2007-01-24 |
Biovation Limited |
Method for reducing immunogenicity of proteins
|
|
WO2000035956A1
(fr)
*
|
1998-12-16 |
2000-06-22 |
Kyowa Hakko Kogyo Co., Ltd. |
Anticorps monoclonal anti-vegf humain
|
|
HRP20130077A2
(hr)
|
1998-12-23 |
2013-07-31 |
Pfizer Inc. |
Humana monoklonalna protutjela za ctla-4
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
US6471429B1
(en)
*
|
1999-01-29 |
2002-10-29 |
Canon Kabushiki Kaisha |
Sheet processing apparatus for discharging sheets in a bundle
|
|
WO2001000678A1
(en)
|
1999-06-30 |
2001-01-04 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies to hiv-1 envelope glycoprotein gp120
|
|
CN102766210B
(zh)
|
1999-08-24 |
2015-07-08 |
E.R.施贵宝&圣斯有限责任公司 |
人ctla-4抗体及其应用
|
|
US6794132B2
(en)
|
1999-10-02 |
2004-09-21 |
Biosite, Inc. |
Human antibodies
|
|
US7135287B1
(en)
|
1999-10-02 |
2006-11-14 |
Biosite, Inc. |
Human antibodies
|
|
WO2001034177A2
(en)
|
1999-11-08 |
2001-05-17 |
The Government Of The United States Of America, A S Represented By The Secretary, Department Of Hea Lth & Human Services, The National Institutes Of Health |
Method of treating a viral infection using antagonists of macrophage colony stimulating factor
|
|
US6517529B1
(en)
*
|
1999-11-24 |
2003-02-11 |
Radius International Limited Partnership |
Hemodialysis catheter
|
|
US6680209B1
(en)
*
|
1999-12-06 |
2004-01-20 |
Biosite, Incorporated |
Human antibodies as diagnostic reagents
|
|
US20030232054A1
(en)
|
2000-01-25 |
2003-12-18 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
EP1285084A1
(en)
|
2000-01-25 |
2003-02-26 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US7108852B2
(en)
*
|
2000-03-20 |
2006-09-19 |
Warner-Lambert Company Llc |
Methods of treating inflammation using antibodies to M-CSF
|
|
US20030059427A1
(en)
|
2000-04-28 |
2003-03-27 |
Force Walker R. |
Isolation and characterization of highly active anti-CD40 antibody
|
|
WO2001092340A2
(en)
*
|
2000-05-26 |
2001-12-06 |
Immunex Corporation |
Use of interleukin-4 antagonists and compositions thereof
|
|
AU2001268427B2
(en)
|
2000-06-16 |
2007-03-29 |
Glaxosmithkline Intellectual Property Limited |
Antibodies that immunospecifically bind to blys
|
|
US7879328B2
(en)
*
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
US20040253242A1
(en)
|
2000-12-05 |
2004-12-16 |
Bowdish Katherine S. |
Rationally designed antibodies
|
|
US7396917B2
(en)
|
2000-12-05 |
2008-07-08 |
Alexion Pharmaceuticals, Inc. |
Rationally designed antibodies
|
|
WO2002059340A1
(en)
|
2001-01-26 |
2002-08-01 |
The Scripps Research Institute |
Immunopolypeptides to hepatitis c virus
|
|
NZ527977A
(en)
|
2001-02-12 |
2005-10-28 |
Medarex Inc |
Human monoclonal antibodies to FC alpha receptor (CD89)
|
|
US20020146753A1
(en)
*
|
2001-04-06 |
2002-10-10 |
Henrik Ditzel |
Autoantibodies to glucose-6-phosphate isomerase and their participation in autoimmune disease
|
|
EP2011802A3
(en)
*
|
2001-04-27 |
2009-04-15 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-CD40 monoclonal antibody
|
|
JP4025881B2
(ja)
|
2001-04-27 |
2007-12-26 |
キリンファーマ株式会社 |
抗ｃｄ４０モノクローナル抗体
|
|
FI112501B
(fi)
|
2001-05-18 |
2003-12-15 |
Valtion Teknillinen |
Heveiiniä sitovat monoklonaaliset vasta-aineet
|
|
AU2002256895B2
(en)
*
|
2001-05-18 |
2008-09-18 |
Kirin Beer Kabushiki Kaisha |
Anti-TRAIL-R antibodies
|
|
JP2005168497A
(ja)
|
2001-05-18 |
2005-06-30 |
Kirin Brewery Co Ltd |
抗ｔｒａｉｌ−ｒ抗体およびその用途
|
|
DE60239535D1
(de)
|
2001-06-18 |
2011-05-05 |
Rosetta Inpharmatics Llc |
Diagnose und prognose von brustkrebspatientinnen
|
|
US7171311B2
(en)
|
2001-06-18 |
2007-01-30 |
Rosetta Inpharmatics Llc |
Methods of assigning treatment to breast cancer patients
|
|
US20040259153A1
(en)
|
2001-08-22 |
2004-12-23 |
Yoshikazu Kurosawa |
Methods for selecting biding molecule
|
|
JP3729841B2
(ja)
|
2001-10-15 |
2005-12-21 |
麒麟麦酒株式会社 |
抗ｈｌａ−ｄｒ抗体の利用
|
|
CN1571797A
(zh)
|
2001-10-15 |
2005-01-26 |
麒麟麦酒株式会社 |
抗hla－dr抗体
|
|
CA2467521A1
(en)
|
2001-11-16 |
2003-07-10 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to blys
|
|
DE60226641D1
(de)
|
2001-12-03 |
2008-06-26 |
Amgen Fremont Inc |
Antikörperkategorisierung auf der grundlage von bindungseigenschaften
|
|
EP1461082A4
(en)
|
2001-12-03 |
2006-06-28 |
Abgenix Inc |
ANTIBODIES AGAINST THE TUMOR ANTIGEN OF CARBON IX ANHYDRASE (CA IX)
|
|
EP1322146A1
(en)
|
2001-12-18 |
2003-06-25 |
Phoenix Precision Technology Corporation |
Method of electroplating solder bumps on an organic circuit board
|
|
JP4562395B2
(ja)
|
2002-01-09 |
2010-10-13 |
メダレックス， インク． |
Ｃｄ３０に対するヒトモノクローナル抗体
|
|
EP1485075A4
(en)
|
2002-02-20 |
2006-04-26 |
Dyax Corp |
MHC-PEPTIDE COMPLEX BINDING LIGANDS
|
|
US7262277B2
(en)
*
|
2002-03-21 |
2007-08-28 |
Eli Lilly And Company |
Antagonistic anti-hFAS ligand human antibodies and fragments thereof
|
|
CN1886512B
(zh)
|
2002-04-23 |
2015-11-25 |
斯克里普斯研究所 |
多肽在叶绿体中的表达以及用于表达多肽的组合物和方法
|
|
WO2003093313A2
(en)
|
2002-04-29 |
2003-11-13 |
Baxter International Inc. |
Antagonists of factor viii interaction with low-density lipoprotein receptor-related protein
|
|
US20040110933A1
(en)
|
2002-09-13 |
2004-06-10 |
Dyax Corporation |
CD44-binding ligands
|
|
US7396913B2
(en)
*
|
2002-10-14 |
2008-07-08 |
Abbott Laboratories |
Erythropoietin receptor binding antibodies
|
|
TWI320716B
(en)
|
2002-10-14 |
2010-02-21 |
Abbott Lab |
Erythropoietin receptor binding antibodies
|
|
CN1787837A
(zh)
|
2002-11-15 |
2006-06-14 |
希龙公司 |
防止和治疗癌转移以及与癌转移相关的骨质损失的方法
|
|
EP1578397B1
(en)
|
2002-11-15 |
2012-12-26 |
Genmab A/S |
Human monoclonal antibodies against cd25
|
|
CL2003002461A1
(es)
|
2002-11-27 |
2005-01-07 |
Dow Chemical Company Agroscien |
Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
|
|
EP1578947A4
(en)
|
2002-12-02 |
2006-12-06 |
Abgenix Inc |
ANTIBODIES TAKEN AGAINST PHOSPHOLIPASE A2 AND USES THEREOF
|
|
WO2004050032A2
(en)
|
2002-12-02 |
2004-06-17 |
Abgenix, Inc. |
Antibodies against drugs of abuse
|
|
US20050009136A1
(en)
*
|
2003-02-19 |
2005-01-13 |
Dyax Corporation |
PAPP-A ligands
|
|
US8067544B2
(en)
|
2003-03-19 |
2011-11-29 |
Curagen Corporation |
Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof
|
|
KR20060035599A
(ko)
|
2003-05-06 |
2006-04-26 |
알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티 |
크립토코커스증 치료용 조성물 및 방법
|
|
US20090005257A1
(en)
|
2003-05-14 |
2009-01-01 |
Jespers Laurent S |
Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire
|
|
CA2526398C
(en)
|
2003-05-21 |
2014-07-15 |
Medarex, Inc. |
Human monoclonal antibodies against bacillus anthracis protective antigen
|
|
WO2004108078A2
(en)
|
2003-06-02 |
2004-12-16 |
Alexion Pharmaceuticals Inc. |
Rationally designed antibodies
|
|
MEP31508A
(hr)
|
2003-07-15 |
2010-10-10 |
Amgen Inc |
Humana anti-ngf neutrališuća antitijela kao selektivni ihibitori ngf signalne kaskade
|
|
JP4680902B2
(ja)
|
2003-07-22 |
2011-05-11 |
バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト |
Ｒｇ１抗体及びその使用
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
WO2005019267A2
(en)
|
2003-08-12 |
2005-03-03 |
Dyax Corp. |
Tie1-binding ligands
|
|
JP2007528721A
(ja)
*
|
2003-08-14 |
2007-10-18 |
ダイアックス コーポレイション |
エンドセリアーゼ−２リガンド
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
WO2005034733A2
(en)
|
2003-10-08 |
2005-04-21 |
North Shore-Long Island Jewish Research Institute |
Methods and compositions for diagnosis and treatment of b cell chronic lymphocytic leukemia
|
|
CN1902228A
(zh)
|
2003-11-07 |
2007-01-24 |
安姆根有限公司 |
猴免疫球蛋白序列
|
|
NZ547588A
(en)
|
2003-11-07 |
2009-05-31 |
Immunex Corp |
Antibodies that bind interleukin-4 receptor
|
|
JP4870348B2
(ja)
|
2003-12-04 |
2012-02-08 |
株式会社ペルセウスプロテオミクス |
細胞表面抗原に対する抗体取得とその抗原同定
|
|
KR101374514B1
(ko)
|
2003-12-10 |
2014-03-13 |
메다렉스, 인코포레이티드 |
Ｉｐ―１０ 항체 및 그의 용도
|
|
ES2399050T3
(es)
|
2003-12-10 |
2013-03-25 |
Medarex, Inc. |
Anticuerpos contra interferón alfa y sus usos
|
|
ES2378767T3
(es)
|
2003-12-23 |
2012-04-17 |
Crucell Holland B.V. |
Molécula de unión humana contra CD1a
|
|
AU2005205533B2
(en)
|
2004-01-07 |
2012-03-22 |
Novartis Vaccines And Diagnostics, Inc. |
M-CSF-specific monoclonal antibody and uses thereof
|
|
EP2857418B1
(en)
|
2004-02-06 |
2017-07-26 |
University of Massachusetts |
Antibodies against Clostridium difficile toxins and uses thereof
|
|
US7271245B2
(en)
*
|
2004-02-13 |
2007-09-18 |
The Scripps Research Institute |
Methods and compositions for inhibition of metastasis
|
|
WO2005086713A2
(en)
|
2004-03-04 |
2005-09-22 |
Kirin Brewery Co., Ltd. |
Role of human endothelial precursor cells and vascular pericytes tumor in angiogenesis
|
|
AU2005227313A1
(en)
|
2004-03-19 |
2005-10-06 |
Amgen Inc. |
Reducing the risk of human and anti-human antibodies through V gene manipulation
|
|
PT1737891E
(pt)
*
|
2004-04-13 |
2013-04-16 |
Hoffmann La Roche |
Anticorpos anti p-selectina
|
|
WO2005109266A1
(en)
|
2004-05-07 |
2005-11-17 |
Snap-On Incorporated |
Tool monitoring system
|
|
US11674240B2
(en)
|
2004-07-06 |
2023-06-13 |
Pfizer Inc. |
Universal antibody libraries
|
|
WO2006020258A2
(en)
|
2004-07-17 |
2006-02-23 |
Imclone Systems Incorporated |
Novel tetravalent bispecific antibody
|
|
MX2007000644A
(es)
|
2004-07-20 |
2007-03-28 |
Symphogen As |
Anticuerpo policlonal recombinante anti-rhesus d y metodos de fabricacion.
|
|
JP2008515774A
(ja)
|
2004-08-03 |
2008-05-15 |
ダイアックス コーポレイション |
ｈＫ１結合タンパク質
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
WO2006017759A2
(en)
|
2004-08-05 |
2006-02-16 |
Kirin Brewery Co., Ltd. |
Tumor endothelial marker-1 (tem1) binding antibodies and uses thereof
|
|
CA2576886A1
(en)
|
2004-08-12 |
2006-02-23 |
Dyax Corp. |
Tie complex binding proteins
|
|
AU2005276787A1
(en)
|
2004-08-23 |
2006-03-02 |
Genpharm International, Inc. |
Binding member towards Pneumolysin
|
|
CA2580981C
(en)
|
2004-09-22 |
2013-10-22 |
Kirin Beer Kabushiki Kaisha |
Stabilized human igg4 antibodies
|
|
CN101056655A
(zh)
|
2004-10-01 |
2007-10-17 |
米德列斯公司 |
治疗cd30阳性淋巴瘤的方法
|
|
KR100619546B1
(ko)
|
2004-10-05 |
2006-09-04 |
아주대학교산학협력단 |
히스톤 ｈ2ａ 및/또는 ｈ2ｂ에 대한 인간 모노클로날자가항체 및 그 단편
|
|
DK1819358T3
(da)
|
2004-11-18 |
2014-10-27 |
Imclone Llc |
Antistoffer mod vaskulær endothel-vækstfaktor-receptor-1
|
|
WO2006071441A2
(en)
|
2004-11-30 |
2006-07-06 |
Curagen Corporation |
Antibodies directed to gpnmb and uses thereof
|
|
ES2371083T3
(es)
*
|
2004-12-21 |
2011-12-27 |
Medimmune Limited |
Anticuerpos dirigidos contra la angiopoyetina-2 y usos de los mismos.
|
|
TW200902555A
(en)
|
2005-01-03 |
2009-01-16 |
Hoffmann La Roche |
Antibodies against IL-13 receptor alpha 1 and uses thereof
|
|
EP1851245B1
(en)
|
2005-01-26 |
2012-10-10 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
EP1848745B1
(en)
|
2005-02-18 |
2014-07-09 |
Medarex, L.L.C. |
Monoclonal antibodies against cd30 lacking in fucosyl residues
|
|
AR054428A1
(es)
|
2005-03-08 |
2007-06-27 |
Pharmacia & Upjohn Co Llc |
Composiciones de anticuerpos anti factor estimulante de colonia de macrofagos (anti-m-csf) que tienen menores niveles de endotoxina
|
|
LT2620450T
(lt)
|
2005-03-08 |
2019-02-11 |
Pfizer Products Inc. |
Anti-ctla-4 antikūnų kompozicijos
|
|
DE602005027258D1
(de)
|
2005-03-14 |
2011-05-12 |
Us Gov Health & Human Serv |
Humane monoklonale antikörper gegen hendra- und nipah-viren
|
|
WO2006105338A2
(en)
|
2005-03-31 |
2006-10-05 |
Xencor, Inc. |
Fc VARIANTS WITH OPTIMIZED PROPERTIES
|
|
EP1874820A4
(en)
|
2005-04-20 |
2010-09-22 |
Amgen Fremont Inc |
HIGH AFFINE, COMPLETELY HUMAN MONOCLONAL ANTIBODY AGAINST INTERLEUKIN-8 AND EPITOPES FOR SUCH ANTIBODIES
|
|
WO2006124269A2
(en)
|
2005-05-16 |
2006-11-23 |
Amgen Fremont Inc. |
Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders
|
|
CA2612241C
(en)
|
2005-07-01 |
2018-11-06 |
Medarex, Inc. |
Human monoclonal antibodies to programmed death ligand 1 (pd-l1)
|
|
WO2007016240A2
(en)
|
2005-07-28 |
2007-02-08 |
Novartis Ag |
Use of antibody to m-csf
|
|
WO2007016285A2
(en)
|
2005-07-28 |
2007-02-08 |
Novartis Ag |
M-csf specific monoclonal antibody and uses thereof
|
|
PE20071101A1
(es)
|
2005-08-31 |
2007-12-21 |
Amgen Inc |
Polipeptidos y anticuerpos
|
|
KR101536506B1
(ko)
*
|
2005-09-07 |
2015-07-14 |
암젠 프레몬트 인코포레이티드 |
액티빈 수용체 유사 키나제-1에 대한 인간 모노클로날 항체
|
|
WO2012084704A1
(en)
|
2010-12-20 |
2012-06-28 |
Merck Serono S.A. |
Indazolyl triazole derivatives as irak inhibitors
|
|
KR101460477B1
(ko)
|
2013-06-18 |
2014-11-10 |
주식회사 엘지화학 |
연신 적층체, 박형 편광자의 제조 방법, 이를 이용하여 제조되는 박형 편광자 및 이를 포함하는 편광판
|
|
JP6319584B2
(ja)
|
2015-02-27 |
2018-05-09 |
京セラドキュメントソリューションズ株式会社 |
画像形成システム
|