|
JPS5531159A
(en)
|
1978-08-26 |
1980-03-05 |
Sumitomo Metal Ind Ltd |
Manufacture of high strength cold rolled steel plate for press working
|
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
|
US4504586A
(en)
*
|
1983-02-03 |
1985-03-12 |
Amgen |
Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
|
|
US4740461A
(en)
|
1983-12-27 |
1988-04-26 |
Genetics Institute, Inc. |
Vectors and methods for transformation of eucaryotic cells
|
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US5573930A
(en)
|
1985-02-05 |
1996-11-12 |
Cetus Oncology Corporation |
DNA encoding various forms of colony stimulating factor-1
|
|
AU594045B2
(en)
|
1985-02-05 |
1990-03-01 |
Chiron Corporation |
Recombinant colony stimulating factor-1
|
|
US5792450A
(en)
|
1985-02-05 |
1998-08-11 |
Chiron Corporation |
Purified human CSF-1
|
|
US5837229A
(en)
|
1985-02-05 |
1998-11-17 |
Chiron Corporation |
Uses of recombinant colony stimulating factor-1
|
|
US6146851A
(en)
|
1985-02-05 |
2000-11-14 |
Chiron Corporation |
DNA encoding NV2 (long form) and carboxy truncated fragments thereof
|
|
US4847201A
(en)
|
1985-02-05 |
1989-07-11 |
Cetus Corporation |
DNA encoding for CSF-1 and accompanying recombinant systems
|
|
AU584417B2
(en)
|
1985-04-01 |
1989-05-25 |
Lonza Group Ag |
Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
|
|
US4968615A
(en)
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US4868119A
(en)
|
1986-12-11 |
1989-09-19 |
Genetics Institute, Inc. |
Hematopoietic growth factors
|
|
MX9203130A
(es)
|
1986-05-06 |
1992-07-01 |
Genetics Inst |
Produccion de m-csf
|
|
US4959455A
(en)
|
1986-07-14 |
1990-09-25 |
Genetics Institute, Inc. |
Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
|
|
GB8624899D0
(en)
|
1986-10-17 |
1986-11-19 |
Sandoz Ltd |
Monoclonal antibodies
|
|
US4912040A
(en)
|
1986-11-14 |
1990-03-27 |
Genetics Institute, Inc. |
Eucaryotic expression system
|
|
US4929700A
(en)
|
1987-04-16 |
1990-05-29 |
Cetus Corporation |
Production of purified, biologically active, bacterially produced recombinant human CSF-1
|
|
CA1339757C
(en)
|
1987-04-16 |
1998-03-17 |
Robert F. Halenbeck |
Production of purified biologically active, bacterially produced recombinant human csf-1
|
|
US5750172A
(en)
|
1987-06-23 |
1998-05-12 |
Pharming B.V. |
Transgenic non human mammal milk
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
US4929455A
(en)
*
|
1988-07-07 |
1990-05-29 |
Mallinckrodt, Inc. |
Flour-based pot pie crusts with improved texture
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
ATE141290T1
(de)
*
|
1989-02-10 |
1996-08-15 |
Cetus Oncology Corp |
M-csf-monoklonale antikörper, die ein neutralisierendes konformationales epitop erkennen
|
|
CA2062975A1
(en)
|
1989-07-14 |
1991-01-15 |
Gail F. Seelig |
Antagonists of gm-csf derived from the carboxyl terminus
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
AU7160391A
(en)
|
1989-12-15 |
1991-07-18 |
Lucien A Aarden |
Cytokine antibody for the treatment of sepsis
|
|
DK0710719T3
(da)
*
|
1990-01-12 |
2007-07-09 |
Amgen Fremont Inc |
Frembringelse af xenogene antistoffer
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5151510A
(en)
|
1990-04-20 |
1992-09-29 |
Applied Biosystems, Inc. |
Method of synethesizing sulfurized oligonucleotide analogs
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
JPH06508511A
(ja)
|
1990-07-10 |
1994-09-29 |
ケンブリッジ アンティボディー テクノロジー リミティド |
特異的な結合ペアーの構成員の製造方法
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
CA2090473A1
(en)
|
1990-08-29 |
1992-03-01 |
Robert M. Kay |
Homologous recombinatin in mammalian cells
|
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US7041871B1
(en)
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
ATE164395T1
(de)
|
1990-12-03 |
1998-04-15 |
Genentech Inc |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
|
CA2060741A1
(en)
|
1991-02-11 |
1992-08-12 |
Robert S. Greenfield |
Gm-csf inhibiting oligopeptides
|
|
EP1279731B1
(en)
|
1991-03-01 |
2007-05-30 |
Dyax Corporation |
Process for the development of binding mini-proteins
|
|
ES2315612T3
(es)
|
1991-04-10 |
2009-04-01 |
The Scripps Research Institute |
Genotecas de receptores heterodimericos usando fagemidos.
|
|
DE4122599C2
(de)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid zum Screenen von Antikörpern
|
|
WO1993004169A1
(en)
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
|
CA2119930C
(en)
|
1991-09-23 |
2002-10-01 |
Hendricus R. J. M. Hoogenboom |
Production of chimeric antibodies - a combinatorial approach
|
|
JPH0595794A
(ja)
*
|
1991-10-04 |
1993-04-20 |
Otsuka Pharmaceut Co Ltd |
ヒトｍ−ｃｓｆ抗体及びヒトｍ−ｃｓｆの測定法
|
|
FI941572A7
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
|
|
EP0618970A1
(en)
|
1991-12-10 |
1994-10-12 |
Dana Farber Cancer Institute |
Reactive neutralizing human anti-gp120 recombinant antibody, dna coding the same and use thereof
|
|
JPH067189A
(ja)
|
1991-12-17 |
1994-01-18 |
Morinaga Milk Ind Co Ltd |
ヒトＭ−ＣＳＦ β型ダイマ−に特異性を有するモノクロ− ナル抗体と、この抗体を産生するハイブリドーマ、お よびこの抗体の利用
|
|
ATE503496T1
(de)
|
1992-02-06 |
2011-04-15 |
Novartis Vaccines & Diagnostic |
Biosynthetisches bindeprotein für tumormarker
|
|
JPH0595794U
(ja)
|
1992-06-04 |
1993-12-27 |
智子 中嶋 |
ものさし目盛り付ボールペン
|
|
JPH08507916A
(ja)
|
1992-06-09 |
1996-08-27 |
カイロン コーポレイション |
Ｍ−ｃｓｆの結晶化
|
|
NZ255101A
(en)
|
1992-07-24 |
1997-08-22 |
Cell Genesys Inc |
A yeast artificial chromosome (yac) vector containing an hprt minigene expressible in murine stem cells and genetically modified rodent therefor
|
|
JP3714683B2
(ja)
|
1992-07-30 |
2005-11-09 |
生化学工業株式会社 |
抗リウマチ剤
|
|
US6177401B1
(en)
|
1992-11-13 |
2001-01-23 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften |
Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
|
|
JPH06194367A
(ja)
|
1992-12-25 |
1994-07-15 |
Morinaga Milk Ind Co Ltd |
リウマチ疾患の診断方法
|
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
|
EP0804070B1
(en)
|
1993-03-09 |
2000-05-24 |
Genzyme Corporation |
Process of isolation of proteins from milk
|
|
JPH06319584A
(ja)
|
1993-05-07 |
1994-11-22 |
Morinaga Milk Ind Co Ltd |
抗ｍ−ｃｓｆモノクロ−ナル抗体と、この抗体を産生 するハイブリド−マ
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
IL112248A0
(en)
|
1994-01-25 |
1995-03-30 |
Warner Lambert Co |
Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
|
|
WO1995029690A1
(en)
|
1994-04-29 |
1995-11-09 |
The Trustees Of The University Of Pennsylvania |
Biologically active peptides and methods of identifying the same
|
|
US5643763A
(en)
|
1994-11-04 |
1997-07-01 |
Genpharm International, Inc. |
Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating
|
|
US6046037A
(en)
|
1994-12-30 |
2000-04-04 |
Hiatt; Andrew C. |
Method for producing immunoglobulins containing protection proteins in plants and their use
|
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US6091001A
(en)
|
1995-03-29 |
2000-07-18 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US5861510A
(en)
|
1995-04-20 |
1999-01-19 |
Pfizer Inc |
Arylsulfonyl hydroxamic acid derivatives as MMP and TNF inhibitors
|
|
AU705616B2
(en)
|
1995-04-21 |
1999-05-27 |
Cell Genesys, Inc. |
Generation of large genomic DNA deletions
|
|
EP1978033A3
(en)
|
1995-04-27 |
2008-12-24 |
Amgen Fremont Inc. |
Human antibodies derived from immunized xenomice
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
GB9520822D0
(en)
|
1995-10-11 |
1995-12-13 |
Wellcome Found |
Therapeutically active compounds
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
PT780386E
(pt)
|
1995-12-20 |
2003-02-28 |
Hoffmann La Roche |
Inibidores de metaloprotease de matriz
|
|
IL125954A
(en)
|
1996-03-05 |
2003-06-24 |
Zeneca Ltd |
Quinazoline derivatives, processes for their preparation, pharmaceutical compositions containing them and use thereof in the manufacture of medicaments having an antiangiogenic and/or vascular permeability reducing effect
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
US5994619A
(en)
|
1996-04-01 |
1999-11-30 |
University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus |
Production of chimeric bovine or porcine animals using cultured inner cell mass cells
|
|
EP0818442A3
(en)
|
1996-07-12 |
1998-12-30 |
Pfizer Inc. |
Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor
|
|
ATE227283T1
(de)
|
1996-07-13 |
2002-11-15 |
Glaxo Group Ltd |
Kondensierte heterozyklische verbindungen als protein kinase inhibitoren
|
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
|
AU3693697A
(en)
|
1996-07-13 |
1998-02-09 |
Glaxo Group Limited |
Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
|
|
CN1225639A
(zh)
|
1996-07-18 |
1999-08-11 |
美国辉瑞有限公司 |
基于次膦酸酯的基质金属蛋白酶抑制剂
|
|
SK21499A3
(en)
|
1996-08-23 |
2000-05-16 |
Pfizer |
Arylsulfonylamino hydroxamic acid derivatives
|
|
ID18494A
(id)
|
1996-10-02 |
1998-04-16 |
Novartis Ag |
Turunan pirazola leburan dan proses pembuatannya
|
|
US6255455B1
(en)
|
1996-10-11 |
2001-07-03 |
The Trustees Of The University Of Pennsylvania |
Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
ATE549918T1
(de)
|
1996-12-03 |
2012-04-15 |
Amgen Fremont Inc |
Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden
|
|
EP0950059B1
(en)
|
1997-01-06 |
2004-08-04 |
Pfizer Inc. |
Cyclic sulfone derivatives
|
|
SK283963B6
(sk)
|
1997-02-03 |
2004-06-08 |
Pfizer Products Inc. |
Deriváty arylsulfonylaminohydroxamovej kyseliny, farmaceutický prostriedok, spôsob inhibície matričných metaloproteináz alebo produkcie faktora nekrózy nádorov
|
|
WO1998034915A1
(en)
|
1997-02-07 |
1998-08-13 |
Pfizer Inc. |
N-hydroxy-beta-sulfonyl-propionamide derivatives and their use as inhibitors of matrix metalloproteinases
|
|
JP3710489B2
(ja)
|
1997-02-11 |
2005-10-26 |
ファイザー・インク |
アリールスルホニルヒドロキサム酸誘導体
|
|
ES2234099T3
(es)
|
1997-03-12 |
2005-06-16 |
Smithkline Beecham Corporation |
Anticuerpos monoclanales humanizados anti-alfa beta 3.
|
|
CA2257247C
(en)
|
1997-04-15 |
2012-09-11 |
Snow Brand Milk Products Co., Ltd. |
Novel protein binding to osteoclastogenesis inhibitory factor and process for producing the same
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
WO1998050356A1
(en)
|
1997-05-07 |
1998-11-12 |
Sugen, Inc. |
2-indolinone derivatives as modulators of protein kinase activity
|
|
CA2290485C
(en)
|
1997-05-21 |
2008-08-05 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
WO1998054093A1
(en)
|
1997-05-30 |
1998-12-03 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
UA61963C2
(en)
|
1997-08-08 |
2003-12-15 |
Pfizer Prod Inc |
Aryloxysulfonylaminohydroxamic acid derivatives
|
|
DE69838172T2
(de)
|
1997-08-22 |
2008-04-10 |
Astrazeneca Ab |
Oxindolylchinazolinderivate als angiogenesehemmer
|
|
WO1999016755A1
(en)
|
1997-09-26 |
1999-04-08 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
JP2001522853A
(ja)
|
1997-11-11 |
2001-11-20 |
ファイザー・プロダクツ・インク |
抗癌剤として有用なチエノピリミジンおよびチエノピリジン誘導体
|
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
GB9800575D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
|
CA2322749A1
(en)
|
1998-03-03 |
1999-09-10 |
Abgenix, Inc. |
Cd147 binding molecules as therapeutics
|
|
JP4462654B2
(ja)
|
1998-03-26 |
2010-05-12 |
ソニー株式会社 |
映像素材選択装置及び映像素材選択方法
|
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
|
TR200003514T2
(tr)
|
1998-05-29 |
2002-05-21 |
Sugen Inc. |
Pirol ikame edilmiş 2-indolinon protein kinaz inhibitörleri
|
|
UA60365C2
(uk)
|
1998-06-04 |
2003-10-15 |
Пфайзер Продактс Інк. |
Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
|
|
AUPP525198A0
(en)
|
1998-08-13 |
1998-09-03 |
Medvet Science Pty. Ltd. |
Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
|
|
AU770555B2
(en)
|
1998-08-17 |
2004-02-26 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
|
EP1004578B1
(en)
|
1998-11-05 |
2004-02-25 |
Pfizer Products Inc. |
5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives
|
|
WO2001054477A2
(en)
|
2000-01-25 |
2001-08-02 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
EP1051432B1
(en)
|
1998-12-08 |
2007-01-24 |
Biovation Limited |
Method for reducing immunogenicity of proteins
|
|
WO2000035956A1
(fr)
*
|
1998-12-16 |
2000-06-22 |
Kyowa Hakko Kogyo Co., Ltd. |
Anticorps monoclonal anti-vegf humain
|
|
HK1041274B
(zh)
*
|
1998-12-23 |
2017-12-01 |
辉瑞大药厂 |
抗ctla-4的人单克隆抗体
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
US6471429B1
(en)
*
|
1999-01-29 |
2002-10-29 |
Canon Kabushiki Kaisha |
Sheet processing apparatus for discharging sheets in a bundle
|
|
WO2001000678A1
(en)
|
1999-06-30 |
2001-01-04 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies to hiv-1 envelope glycoprotein gp120
|
|
CN1371416B
(zh)
|
1999-08-24 |
2012-10-10 |
梅达里克斯公司 |
人ctla-4抗体及其应用
|
|
US6794132B2
(en)
|
1999-10-02 |
2004-09-21 |
Biosite, Inc. |
Human antibodies
|
|
US7135287B1
(en)
|
1999-10-02 |
2006-11-14 |
Biosite, Inc. |
Human antibodies
|
|
AU1759501A
(en)
|
1999-11-08 |
2001-06-06 |
Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The |
Method of treating a viral infection using antagonists of macrophage colony stimulating factor
|
|
US6517529B1
(en)
|
1999-11-24 |
2003-02-11 |
Radius International Limited Partnership |
Hemodialysis catheter
|
|
US6680209B1
(en)
|
1999-12-06 |
2004-01-20 |
Biosite, Incorporated |
Human antibodies as diagnostic reagents
|
|
US20030232054A1
(en)
|
2000-01-25 |
2003-12-18 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US7108852B2
(en)
|
2000-03-20 |
2006-09-19 |
Warner-Lambert Company Llc |
Methods of treating inflammation using antibodies to M-CSF
|
|
US20030059427A1
(en)
|
2000-04-28 |
2003-03-27 |
Force Walker R. |
Isolation and characterization of highly active anti-CD40 antibody
|
|
EP2292665B1
(en)
|
2000-05-26 |
2015-07-08 |
Immunex Corporation |
Use of interleukin-4 antibodies and compositions thereof
|
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
PT2275449T
(pt)
|
2000-06-16 |
2016-12-27 |
Human Genome Sciences Inc |
Anticorpos que se ligam imunoespecificamente a blys
|
|
US20040253242A1
(en)
|
2000-12-05 |
2004-12-16 |
Bowdish Katherine S. |
Rationally designed antibodies
|
|
US7396917B2
(en)
|
2000-12-05 |
2008-07-08 |
Alexion Pharmaceuticals, Inc. |
Rationally designed antibodies
|
|
WO2002059340A1
(en)
|
2001-01-26 |
2002-08-01 |
The Scripps Research Institute |
Immunopolypeptides to hepatitis c virus
|
|
US7192582B2
(en)
|
2001-02-12 |
2007-03-20 |
Medarex, Inc. |
Human monoclonal antibodies to FC alpha receptor (CD89)
|
|
US20020146753A1
(en)
|
2001-04-06 |
2002-10-10 |
Henrik Ditzel |
Autoantibodies to glucose-6-phosphate isomerase and their participation in autoimmune disease
|
|
ATE374214T1
(de)
|
2001-04-27 |
2007-10-15 |
Kirin Brewery |
Monoklonaler anti-cd-40-antikörper
|
|
JP4025881B2
(ja)
|
2001-04-27 |
2007-12-26 |
キリンファーマ株式会社 |
抗ｃｄ４０モノクローナル抗体
|
|
FI112501B
(fi)
|
2001-05-18 |
2003-12-15 |
Valtion Teknillinen |
Heveiiniä sitovat monoklonaaliset vasta-aineet
|
|
WO2002094880A1
(fr)
|
2001-05-18 |
2002-11-28 |
Kirin Beer Kabushiki Kaisha |
Anticorps anti-trail-r
|
|
JP2005168497A
(ja)
|
2001-05-18 |
2005-06-30 |
Kirin Brewery Co Ltd |
抗ｔｒａｉｌ−ｒ抗体およびその用途
|
|
US7171311B2
(en)
|
2001-06-18 |
2007-01-30 |
Rosetta Inpharmatics Llc |
Methods of assigning treatment to breast cancer patients
|
|
CA2451074C
(en)
|
2001-06-18 |
2014-02-11 |
Rosetta Inpharmatics, Inc. |
Diagnosis and prognosis of breast cancer patients
|
|
JP4190005B2
(ja)
|
2001-08-22 |
2008-12-03 |
株式会社抗体研究所 |
結合性分子の選択方法
|
|
US7262278B2
(en)
|
2001-10-15 |
2007-08-28 |
Kirin Beer Kabushiki Kaisha |
Anti-HLA-DR antibody
|
|
JP3729841B2
(ja)
|
2001-10-15 |
2005-12-21 |
麒麟麦酒株式会社 |
抗ｈｌａ−ｄｒ抗体の利用
|
|
CA2467521A1
(en)
|
2001-11-16 |
2003-07-10 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to blys
|
|
WO2003048328A2
(en)
|
2001-12-03 |
2003-06-12 |
Abgenix, Inc. |
Antibodies against carboxic anhydrase ix (ca ix) tumor antigen
|
|
AU2002357060A1
(en)
|
2001-12-03 |
2003-06-17 |
Abgenix, Inc. |
Antibody categorization based on binding characteristics
|
|
EP1322146A1
(en)
|
2001-12-18 |
2003-06-25 |
Phoenix Precision Technology Corporation |
Method of electroplating solder bumps on an organic circuit board
|
|
KR100668538B1
(ko)
|
2002-01-09 |
2007-01-16 |
메다렉스, 인코포레이티드 |
Ｃｄ３０에 대한 인간 모노클로날 항체
|
|
EP1485075A4
(en)
|
2002-02-20 |
2006-04-26 |
Dyax Corp |
MHC-PEPTIDE COMPLEX BINDING LIGANDS
|
|
PT1490405E
(pt)
|
2002-03-21 |
2007-11-07 |
Lilly Co Eli |
Anticorpos humanos anti-ligando de hfas antagonistas e fragmentos dos mesmos
|
|
JP2005537784A
(ja)
|
2002-04-23 |
2005-12-15 |
ザ スクリップス リサーチ インスティテュート |
葉緑体におけるポリペプチドの発現、ならびにそのポリペプチドを発現するための組成物および方法
|
|
WO2003093313A2
(en)
|
2002-04-29 |
2003-11-13 |
Baxter International Inc. |
Antagonists of factor viii interaction with low-density lipoprotein receptor-related protein
|
|
US20040110933A1
(en)
|
2002-09-13 |
2004-06-10 |
Dyax Corporation |
CD44-binding ligands
|
|
US7396913B2
(en)
|
2002-10-14 |
2008-07-08 |
Abbott Laboratories |
Erythropoietin receptor binding antibodies
|
|
TWI320716B
(en)
|
2002-10-14 |
2010-02-21 |
Abbott Lab |
Erythropoietin receptor binding antibodies
|
|
US7438907B2
(en)
|
2002-11-15 |
2008-10-21 |
Genmab A/S |
Human monoclonal antibodies against CD25
|
|
DK1572106T3
(da)
|
2002-11-15 |
2010-08-23 |
Novartis Vaccines & Diagnostic |
Fremgangsmåde til forebyggelse og behandling af cancermetastase og knogletab forbundet med cancermetastase
|
|
AR042145A1
(es)
|
2002-11-27 |
2005-06-08 |
Dow Agrociences Llc |
Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
|
|
AU2003298799A1
(en)
|
2002-12-02 |
2004-06-23 |
Abgenix, Inc. |
Antibodies directed to phospholipase a2 and uses thereof
|
|
WO2004050032A2
(en)
|
2002-12-02 |
2004-06-17 |
Abgenix, Inc. |
Antibodies against drugs of abuse
|
|
US20050009136A1
(en)
|
2003-02-19 |
2005-01-13 |
Dyax Corporation |
PAPP-A ligands
|
|
US8067544B2
(en)
|
2003-03-19 |
2011-11-29 |
Curagen Corporation |
Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof
|
|
AU2004236263A1
(en)
|
2003-05-06 |
2004-11-18 |
Albert Einstein College Of Medicine Of Yeshiva University |
Compositions and methods for treatment of cryptococcosis
|
|
US20090005257A1
(en)
|
2003-05-14 |
2009-01-01 |
Jespers Laurent S |
Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire
|
|
AU2004270103B2
(en)
|
2003-05-21 |
2012-02-23 |
E. R. Squibb & Sons, L.L.C. |
Human monoclonal antibodies against Bacillusanthracis protective antigen
|
|
WO2004108078A2
(en)
|
2003-06-02 |
2004-12-16 |
Alexion Pharmaceuticals Inc. |
Rationally designed antibodies
|
|
EP1648509B8
(en)
|
2003-07-15 |
2012-10-24 |
Amgen Inc. |
Human anti-ngf neutralizing antibodies as selective ngf pathway inhibitors
|
|
TWI353992B
(en)
|
2003-07-22 |
2011-12-11 |
Schering Ag |
Rg1 antibodies and uses thereof
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
US7348001B2
(en)
|
2003-08-12 |
2008-03-25 |
Dyax Corp. |
Tie1-binding ligands
|
|
US7273610B2
(en)
|
2003-08-14 |
2007-09-25 |
Dyax Corp. |
Endotheliase-2 ligands
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
US8119340B2
(en)
|
2003-10-08 |
2012-02-21 |
The Feinstein Institute For Medical Research |
Methods and compositions for diagnosis and treatment of B cell chronic lymphocytic leukemia
|
|
EP1692184B1
(en)
|
2003-11-07 |
2012-03-07 |
Immunex Corporation |
Antibodies that bind interleukin-4 receptor
|
|
WO2005047325A2
(en)
|
2003-11-07 |
2005-05-26 |
Amgen Inc. |
Monkey immunoglobulin sequences
|
|
JP4870348B2
(ja)
|
2003-12-04 |
2012-02-08 |
株式会社ペルセウスプロテオミクス |
細胞表面抗原に対する抗体取得とその抗原同定
|
|
SI1691837T1
(sl)
|
2003-12-10 |
2012-11-30 |
Medarex Inc |
Ip protitelesa in njihova uporaba
|
|
IN2009KN02655A
(enExample)
|
2003-12-10 |
2015-10-23 |
Medarex Inc |
|
|
ES2378767T3
(es)
|
2003-12-23 |
2012-04-17 |
Crucell Holland B.V. |
Molécula de unión humana contra CD1a
|
|
SI1704166T1
(sl)
|
2004-01-07 |
2015-06-30 |
Novartis Vaccines And Diagnostics, Inc. |
M-scf specifiäśno monoklonsko protitelo in uporabe le-tega
|
|
DK2270045T3
(en)
|
2004-02-06 |
2015-04-07 |
Univ Massachusetts |
ANTIBODIES AGAINST CLOSTRIDIUM DIFFICILE TOXINES AND APPLICATIONS THEREOF
|
|
US7271245B2
(en)
|
2004-02-13 |
2007-09-18 |
The Scripps Research Institute |
Methods and compositions for inhibition of metastasis
|
|
WO2005086713A2
(en)
|
2004-03-04 |
2005-09-22 |
Kirin Brewery Co., Ltd. |
Role of human endothelial precursor cells and vascular pericytes tumor in angiogenesis
|
|
AU2005227313A1
(en)
|
2004-03-19 |
2005-10-06 |
Amgen Inc. |
Reducing the risk of human and anti-human antibodies through V gene manipulation
|
|
EP2374817B1
(en)
|
2004-04-13 |
2017-09-06 |
F. Hoffmann-La Roche AG |
Anti-P-selectin antibodies
|
|
WO2005109266A1
(en)
|
2004-05-07 |
2005-11-17 |
Snap-On Incorporated |
Tool monitoring system
|
|
MX2007000103A
(es)
|
2004-07-06 |
2007-05-11 |
Bioren Inc |
Bibliotecas de anticuerpos universales.
|
|
JP2008512352A
(ja)
|
2004-07-17 |
2008-04-24 |
イムクローン システムズ インコーポレイティド |
新規な四価の二重特異性抗体
|
|
CA2574062A1
(en)
|
2004-07-20 |
2006-01-26 |
Symphogen A/S |
Anti-rhesus d recombinant polyclonal antibody and methods of manufacture
|
|
AU2005271523B2
(en)
|
2004-08-03 |
2011-09-15 |
Dyax Corp. |
hk1-binding proteins
|
|
WO2006017759A2
(en)
|
2004-08-05 |
2006-02-16 |
Kirin Brewery Co., Ltd. |
Tumor endothelial marker-1 (tem1) binding antibodies and uses thereof
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
WO2006020706A2
(en)
|
2004-08-12 |
2006-02-23 |
Dyax Corp. |
Tie complex binding proteins
|
|
EP1791867A2
(en)
|
2004-08-23 |
2007-06-06 |
Genesto A/S |
Binding member towards pneumolysin
|
|
US8911726B2
(en)
|
2004-09-22 |
2014-12-16 |
Kyowa Hakko Kirin Co., Ltd |
Stabilized human Igg4 antibodies
|
|
WO2006039644A2
(en)
|
2004-10-01 |
2006-04-13 |
Medarex, Inc. |
Methods of treating cd30 positive lymphomas
|
|
KR100619546B1
(ko)
|
2004-10-05 |
2006-09-04 |
아주대학교산학협력단 |
히스톤 ｈ2ａ 및/또는 ｈ2ｂ에 대한 인간 모노클로날자가항체 및 그 단편
|
|
SI1819358T1
(sl)
|
2004-11-18 |
2014-10-30 |
Imclone Llc |
Protitelesa proti receptorju 1 za vaskularni endotelijski rastni dejavnik (vegfr-1)
|
|
EP2305716B1
(en)
|
2004-11-30 |
2014-10-22 |
Celldex Therapeutics, Inc. |
Antibodies directed to gpnmb and uses thereof
|
|
AU2005319382B2
(en)
|
2004-12-21 |
2011-04-07 |
Astrazeneca Ab |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
TWI306862B
(en)
|
2005-01-03 |
2009-03-01 |
Hoffmann La Roche |
Antibodies against il-13 receptor alpha 1 and uses thereof
|
|
AU2006208286A1
(en)
|
2005-01-26 |
2006-08-03 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
RU2492186C2
(ru)
|
2005-02-18 |
2013-09-10 |
Медарекс Ллс |
Выделенное анти-cd30 антитело (варианты), хозяйская клетка, способ получения химерного или гуманизированного варианта анти-cd30 антител (варианты), способ ингибирования роста клеток cd30+ и способ ингибирования роста опухолевых клеток, экспрессирующих cd30
|
|
US20090110681A1
(en)
|
2005-03-08 |
2009-04-30 |
Pfizer, Inc. |
Anti-M-CSF Antibody Compositions
|
|
EP1858928A2
(en)
|
2005-03-08 |
2007-11-28 |
Pharmacia & Upjohn Company LLC |
Anti-m-csf antibody compositions having reduced levels of endotoxin
|
|
ATE503770T1
(de)
|
2005-03-14 |
2011-04-15 |
Us Gov Health & Human Serv |
Humane monoklonale antikörper gegen hendra- und nipah-viren
|
|
CA2602663A1
(en)
|
2005-03-31 |
2006-10-05 |
Xencor, Inc. |
Fc variants with optimized properties
|
|
WO2006113643A2
(en)
|
2005-04-20 |
2006-10-26 |
Amgen Fremont Inc. |
High affinity fully human monoclonal antibodies to interleukin-8 and epitopes for such antibodies
|
|
WO2006124269A2
(en)
|
2005-05-16 |
2006-11-23 |
Amgen Fremont Inc. |
Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders
|
|
AU2006265108C1
(en)
|
2005-07-01 |
2013-01-17 |
E. R. Squibb & Sons, L.L.C. |
Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
|
|
ES2538036T3
(es)
|
2005-07-28 |
2015-06-16 |
Novartis Ag |
Uso de anticuerpo a M-CSF
|
|
EP2311876A3
(en)
|
2005-07-28 |
2011-04-27 |
Novartis AG |
M-CSF-specific monoclonal antibody and uses thereof
|
|
PE20071101A1
(es)
|
2005-08-31 |
2007-12-21 |
Amgen Inc |
Polipeptidos y anticuerpos
|
|
DOP2006000195A
(es)
|
2005-09-07 |
2017-08-15 |
Amgen Fremont Inc |
Anticuerpos monoclonales humanos para la quinasa-1 tipo receptor de activina
|
|
BR122021014375B1
(pt)
|
2010-12-20 |
2021-11-30 |
Merck Serono S.A. |
Processo para preparação de derivados de indazolil triazol
|
|
KR101460477B1
(ko)
|
2013-06-18 |
2014-11-10 |
주식회사 엘지화학 |
연신 적층체, 박형 편광자의 제조 방법, 이를 이용하여 제조되는 박형 편광자 및 이를 포함하는 편광판
|
|
JP6319584B2
(ja)
|
2015-02-27 |
2018-05-09 |
京セラドキュメントソリューションズ株式会社 |
画像形成システム
|