JP2010259446A5 - - Google Patents
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- Publication number
- JP2010259446A5 JP2010259446A5 JP2010176512A JP2010176512A JP2010259446A5 JP 2010259446 A5 JP2010259446 A5 JP 2010259446A5 JP 2010176512 A JP2010176512 A JP 2010176512A JP 2010176512 A JP2010176512 A JP 2010176512A JP 2010259446 A5 JP2010259446 A5 JP 2010259446A5
- Authority
- JP
- Japan
- Prior art keywords
- poxvirus
- gene
- recombinant poxvirus
- recombinant
- homologous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200200752 | 2002-05-16 | ||
| DKPA200200753 | 2002-05-16 | ||
| DKPA200200752 | 2002-05-16 | ||
| DKPA200200753 | 2002-05-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004506501A Division JP4693092B2 (ja) | 2002-05-16 | 2003-05-14 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010259446A JP2010259446A (ja) | 2010-11-18 |
| JP2010259446A5 true JP2010259446A5 (OSRAM) | 2011-07-28 |
| JP5777199B2 JP5777199B2 (ja) | 2015-09-09 |
Family
ID=29551228
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004506500A Expired - Lifetime JP4895505B2 (ja) | 2002-05-16 | 2003-05-14 | 変異ワクシニアウイルスアンカラ(mva)ゲノム中の挿入部位としての遺伝子間領域 |
| JP2004506501A Expired - Lifetime JP4693092B2 (ja) | 2002-05-16 | 2003-05-14 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
| JP2010176512A Expired - Lifetime JP5777199B2 (ja) | 2002-05-16 | 2010-08-05 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
| JP2010176511A Pending JP2011004755A (ja) | 2002-05-16 | 2010-08-05 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004506500A Expired - Lifetime JP4895505B2 (ja) | 2002-05-16 | 2003-05-14 | 変異ワクシニアウイルスアンカラ(mva)ゲノム中の挿入部位としての遺伝子間領域 |
| JP2004506501A Expired - Lifetime JP4693092B2 (ja) | 2002-05-16 | 2003-05-14 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010176511A Pending JP2011004755A (ja) | 2002-05-16 | 2010-08-05 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Country Status (22)
| Country | Link |
|---|---|
| US (14) | US7550147B2 (OSRAM) |
| EP (3) | EP1407033B1 (OSRAM) |
| JP (4) | JP4895505B2 (OSRAM) |
| KR (4) | KR101138067B1 (OSRAM) |
| CN (6) | CN101831411A (OSRAM) |
| AT (1) | ATE315660T1 (OSRAM) |
| AU (4) | AU2003236646B2 (OSRAM) |
| BR (2) | BR0310051A (OSRAM) |
| CA (3) | CA2812019A1 (OSRAM) |
| DE (1) | DE60303218T2 (OSRAM) |
| DK (2) | DK1407033T3 (OSRAM) |
| EA (3) | EA007811B1 (OSRAM) |
| ES (1) | ES2256776T3 (OSRAM) |
| IL (4) | IL164177A0 (OSRAM) |
| MX (2) | MXPA04011194A (OSRAM) |
| NO (3) | NO334273B1 (OSRAM) |
| NZ (2) | NZ536502A (OSRAM) |
| PL (2) | PL218318B1 (OSRAM) |
| PT (1) | PT1407033E (OSRAM) |
| SI (1) | SI1407033T1 (OSRAM) |
| UA (1) | UA82479C2 (OSRAM) |
| WO (2) | WO2003097845A1 (OSRAM) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4101327C1 (OSRAM) * | 1991-01-18 | 1991-10-24 | Mercedes-Benz Aktiengesellschaft, 7000 Stuttgart, De | |
| AU3163902A (en) * | 2000-11-23 | 2002-06-03 | Bavarian Nordic Res Inst As | Modified vaccinia ankara virus variant |
| WO2003088994A2 (en) * | 2002-04-19 | 2003-10-30 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| EA007811B1 (ru) * | 2002-05-16 | 2007-02-27 | Бавариан Нордик А/С | Межгенные области, используемые в качестве инсерционных сайтов в геноме модифицированного вируса коровьей оспы анкара (mva) |
| US7501127B2 (en) * | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| ATE393212T2 (de) * | 2002-09-05 | 2008-05-15 | Bavarian Nordic As | Verfahren zur amplifikation von einem poxvirus in serumfreien verhältnissen |
| EP1601333B1 (en) * | 2003-02-20 | 2013-01-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services | Novel insertion sites in pox vectors |
| GB2402391A (en) * | 2003-06-04 | 2004-12-08 | Oxxon Pharmaccines Ltd | Fowlpox recombinant genome |
| EP1807508A4 (en) * | 2004-11-05 | 2008-03-12 | Us Gov Health & Human Serv | METHODS FOR PREPARING CELLS AND VIRUSES |
| HUE030037T2 (en) | 2005-02-23 | 2017-04-28 | Bavarian Nordic As | Use of modified anemic virus for rapid induction of immunity against gluten virus or other agents |
| US8741633B2 (en) * | 2006-05-19 | 2014-06-03 | Glycofi, Inc. | Recombinant vectors |
| EP2062023B2 (en) * | 2006-08-25 | 2016-11-09 | The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services | Intergenic sites between conserved genes in the genome of modified vaccinia ankara (mva) vaccinia virus |
| US8052968B2 (en) * | 2006-10-16 | 2011-11-08 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
| US8440202B2 (en) * | 2006-11-09 | 2013-05-14 | The United States Of America As Represented By The Secretary Of The Navy | Induction of an immune response against dengue virus using the prime-boost approach |
| ES2517615T3 (es) * | 2006-11-09 | 2014-11-03 | The United States Of America As Represented By The Secretary Of The Navy | Inducción de una respuesta inmunitaria frente al virus del dengue usando un enfoque de sensibilización-refuerzo |
| RU2482189C2 (ru) * | 2007-01-30 | 2013-05-20 | Трансген С.А. | Полипептиды е2 папилломавируса, применяемые для вакцинации |
| US8268327B2 (en) | 2007-04-27 | 2012-09-18 | Bavarian Nordic A/S | Immediate protection against pathogens via MVA |
| EP2162544B1 (en) * | 2007-05-15 | 2013-04-17 | Transgene SA | Vectors for multiple gene expression |
| TW200907058A (en) * | 2007-05-30 | 2009-02-16 | Wyeth Corp | Raccoon poxvirus expressing rabies glycoproteins |
| US20080299149A1 (en) * | 2007-05-30 | 2008-12-04 | Wyeth | Raccoon Poxvirus Expressing Genes of Feline Antigens |
| EP2207564B1 (en) * | 2007-10-18 | 2016-10-05 | Bavarian Nordic A/S | Use of mva to treat prostate cancer |
| EP2303322A1 (en) * | 2008-06-20 | 2011-04-06 | Bavarian Nordic A/S | Recombinant modified vaccinia virus measles vaccine |
| KR100894430B1 (ko) * | 2008-11-11 | 2009-04-22 | 시스템디엔디(주) | 초음파, 음향 및 온도변화를 이용한 밸브의 유체누설 측정장치 및 이를 이용한 유체누설 측정방법 |
| EA024749B1 (ru) | 2008-11-21 | 2016-10-31 | Бавариан Нордик А/С | Экспрессионный вектор со сниженным уровнем внутримолекулярной рекомбинации, содержащий гомологичные или гетерологичные нуклеотидные последовательности |
| US8580276B2 (en) | 2009-06-05 | 2013-11-12 | City Of Hope | Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof |
| SG178909A1 (en) | 2009-10-08 | 2012-04-27 | Bavarian Nordic As | Generation of a broad t-cell response in humans against hiv |
| JP5789263B2 (ja) | 2009-10-16 | 2015-10-07 | ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズThe U.S.A.As Represented By The Secretary,Department Of Health And Human Services | 再構築された挿入部位を含有する組換え改変ワクシニアアンカラ(mva)ワクシニアウイルス |
| WO2011087839A1 (en) | 2009-12-22 | 2011-07-21 | Baxter International Inc. | Vaccine to influenza a virus |
| CN103118709A (zh) * | 2010-03-26 | 2013-05-22 | 新兴产品开发盖瑟斯堡有限公司 | 流感病毒基质2蛋白的胞外域、其表达系统和应用 |
| US10087423B2 (en) | 2010-07-20 | 2018-10-02 | Bavarian Nordic A/S | Method for harvesting expression products |
| AU2011305348A1 (en) * | 2010-09-23 | 2013-04-18 | Baxter Healthcare Sa | Recombinant viral vectors and methods for inducing an immune response to yellow fever virus |
| US9173933B2 (en) | 2010-10-15 | 2015-11-03 | Bavarian Nordic A/S | Recombinant modified vaccinia virus Ankara influenza vaccine |
| CN114262690A (zh) | 2011-04-15 | 2022-04-01 | 吉恩勒克斯公司 | 减毒的痘苗病毒的克隆毒株及其使用方法 |
| EP2788021B1 (en) | 2011-12-09 | 2017-01-18 | Bavarian Nordic A/S | Poxvirus vector for the expression of bacterial antigens linked to tetanus toxin fragment c |
| EP2620446A1 (en) | 2012-01-27 | 2013-07-31 | Laboratorios Del Dr. Esteve, S.A. | Immunogens for HIV vaccination |
| SG11201408101TA (en) | 2012-06-05 | 2015-01-29 | Univ Australian | Vaccination with interleukin-4 antagonists |
| IN2015DN01448A (OSRAM) | 2012-08-01 | 2015-07-03 | Bavarian Nordic As | |
| WO2014043535A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions for the treatment of cancer |
| US20140140959A1 (en) | 2012-10-05 | 2014-05-22 | Aladar A. Szalay | Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes |
| AU2013331328B2 (en) | 2012-10-19 | 2018-05-31 | Bavarian Nordic A/S | Methods and compositions for the treatment of cancer |
| WO2014139587A1 (en) * | 2013-03-15 | 2014-09-18 | Okairòs Ag | Improved poxviral vaccines |
| CN105163756A (zh) * | 2013-03-15 | 2015-12-16 | 赛门蒂斯有限公司 | 免疫调节 |
| DE102013004595A1 (de) | 2013-03-15 | 2014-09-18 | Emergent Product Development Germany Gmbh | RSV-Impfstoffe |
| US10238700B2 (en) | 2014-01-02 | 2019-03-26 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| KR101623498B1 (ko) | 2014-10-16 | 2016-05-24 | 대한민국 | 약독화 백시니아 바이러스주 kvac103 |
| KR101645642B1 (ko) | 2014-10-16 | 2016-08-11 | 대한민국 | Kvac103 유래의 재조합 백시니아 바이러스 |
| EP3261669B1 (en) | 2015-02-25 | 2022-08-03 | Memorial Sloan Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| US10548930B2 (en) | 2015-04-17 | 2020-02-04 | Memorial Sloan Kettering Cancer Center | Use of MVA or MVAΔE3L as immunotherapeutic agents against solid tumors |
| KR20160140075A (ko) * | 2015-05-29 | 2016-12-07 | 코오롱생명과학 주식회사 | 폭스바이러스 유래 프로모터 및 이를 포함하는 벡터 |
| CA2987159A1 (en) | 2015-06-15 | 2016-12-22 | Bavarian Nordic A/S | Recombinant modified vaccinia virus ankara (mva) foot and mouth disease virus (fmdv) vaccine |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| CN106591361A (zh) * | 2015-10-20 | 2017-04-26 | 钱文斌 | 一种重组痘溶瘤病毒及其构建方法和应用 |
| CN116064669A (zh) | 2016-01-08 | 2023-05-05 | 吉奥瓦科斯公司 | 用于产生对肿瘤相关抗原的免疫应答的组合物和方法 |
| HUE059343T2 (hu) * | 2016-01-29 | 2022-11-28 | Bavarian Nordic As | Rekombináns, módosított Ankara Vaccinia vírus (MVA) és ló encephalitis vírus oltóanyag |
| BR112018015696A2 (pt) * | 2016-02-03 | 2018-12-26 | Geovax Inc | composições e métodos para gerar uma resposta imune para um flavivírus |
| WO2017147553A2 (en) | 2016-02-25 | 2017-08-31 | Memorial Sloan-Kettering Cancer Center | Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human flt3l or gm-csf for cancer immunotherapy |
| IL261321B2 (en) | 2016-02-25 | 2023-12-01 | Memorial Sloan Kettering Cancer Center | Recombinant MVA or MVADELE3L expressing human FLT3L and their use as immunotherapeutic agents against solid tumors |
| WO2017192418A1 (en) | 2016-05-02 | 2017-11-09 | Janssen Vaccine & Prevention B.V. | Therapeutic hpv vaccine combinations |
| EP4331676A3 (en) * | 2016-08-19 | 2024-05-15 | Sementis Limited | Viral vaccines |
| WO2018064516A1 (en) * | 2016-09-30 | 2018-04-05 | Monsanto Technology Llc | Method for selecting target sites for site-specific genome modification in plants |
| CN111107872A (zh) | 2017-05-12 | 2020-05-05 | 纪念斯隆-凯特林癌症中心 | 有用于癌症免疫疗法的牛痘病毒突变体 |
| BR112019026126A2 (pt) * | 2017-06-15 | 2020-06-30 | Janssen Vaccines & Prevention B.V. | vetores de poxvírus que codificam antígenos do hiv e métodos de uso dos mesmos |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| JP2021535730A (ja) * | 2018-05-11 | 2021-12-23 | シティ・オブ・ホープCity of Hope | 複数の部位メガロウイルス(cmv)抗原の発現のためのmvaベクター及びその使用 |
| JP2021523712A (ja) | 2018-05-11 | 2021-09-09 | シティ・オブ・ホープCity of Hope | 安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 |
| AU2019339535B2 (en) | 2018-09-15 | 2025-11-20 | Memorial Sloan Kettering Cancer Center | Recombinant poxviruses for cancer immunotherapy |
| CN111979204B (zh) * | 2019-05-24 | 2023-10-13 | 杭州功楚生物科技有限公司 | 携带海绵凝集素基因的溶瘤痘苗病毒、构建方法及用途 |
| AU2020384323A1 (en) | 2019-11-14 | 2022-06-02 | Aelix Therapeutics, S.L. | Dosage regimens for vaccines |
| EP3842065A1 (en) * | 2019-12-23 | 2021-06-30 | Transgene | Process for designing a recombinant poxvirus for a therapeutic vaccine |
| US20210299245A1 (en) * | 2020-03-31 | 2021-09-30 | Sementis Limited | Attenuated poxvirus vector based vaccine for protection against covid-19 |
| KR20240001116A (ko) | 2021-02-02 | 2024-01-03 | 지오박스, 인크. | 백신접종 동안 t-세포 프라이밍을 증진시키는 데 사용하기 위한 바이러스 구축물 |
| CA3260631A1 (en) | 2022-07-08 | 2024-01-11 | Viromissile, Inc. | Oncolytic and recombinant vaccine viruses and their methods of use |
| FR3160186A1 (fr) | 2024-03-13 | 2025-09-19 | Odimma Therapeutics | Vecteur non-viral pour transcription augmentee |
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| US5338683A (en) * | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| JPH0795956B2 (ja) * | 1986-09-22 | 1995-10-18 | 京都大学長 | ポックスウイルス由来発現制御領域 |
| US5093258A (en) * | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
| US5225336A (en) * | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
| US5651972A (en) | 1989-04-21 | 1997-07-29 | University Of Florida Research Foundation, Inc. | Use of recombinant swine poxvirus as a live vaccine vector |
| US5514375A (en) | 1990-08-15 | 1996-05-07 | Virogenetics Corporation | Flavivirus recombinant poxvirus vaccine |
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| EP0753581A1 (en) * | 1995-07-10 | 1997-01-15 | Immuno Ag | Improved recombinant eukaryotic cytoplasmic viruses, method for their production and their use as vaccines |
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| EA007811B1 (ru) | 2002-05-16 | 2007-02-27 | Бавариан Нордик А/С | Межгенные области, используемые в качестве инсерционных сайтов в геноме модифицированного вируса коровьей оспы анкара (mva) |
| US7300658B2 (en) * | 2002-11-25 | 2007-11-27 | Bavarian Nordic A/S | Recombinant poxvirus comprising at least two compox ATI promoters |
-
2003
- 2003-05-14 EA EA200401507A patent/EA007811B1/ru not_active IP Right Cessation
- 2003-05-14 KR KR1020107021891A patent/KR101138067B1/ko not_active Expired - Lifetime
- 2003-05-14 IL IL16417703A patent/IL164177A0/xx active IP Right Grant
- 2003-05-14 PL PL372088A patent/PL218318B1/pl unknown
- 2003-05-14 BR BR0310051A patent/BR0310051A/pt not_active IP Right Cessation
- 2003-05-14 EP EP20030752741 patent/EP1407033B1/en not_active Expired - Lifetime
- 2003-05-14 US US10/514,761 patent/US7550147B2/en not_active Expired - Lifetime
- 2003-05-14 US US10/510,189 patent/US7338662B2/en not_active Expired - Lifetime
- 2003-05-14 CN CN200910208520A patent/CN101831411A/zh active Pending
- 2003-05-14 CA CA 2812019 patent/CA2812019A1/en not_active Abandoned
- 2003-05-14 JP JP2004506500A patent/JP4895505B2/ja not_active Expired - Lifetime
- 2003-05-14 WO PCT/EP2003/005045 patent/WO2003097845A1/en not_active Ceased
- 2003-05-14 MX MXPA04011194A patent/MXPA04011194A/es active IP Right Grant
- 2003-05-14 NZ NZ536502A patent/NZ536502A/en not_active IP Right Cessation
- 2003-05-14 KR KR1020047018293A patent/KR101005630B1/ko not_active Expired - Lifetime
- 2003-05-14 NZ NZ536501A patent/NZ536501A/en not_active IP Right Cessation
- 2003-05-14 CA CA2481799A patent/CA2481799C/en not_active Expired - Lifetime
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