|
US7217689B1
(en)
|
1989-10-13 |
2007-05-15 |
Amgen Inc. |
Glycosylation analogs of erythropoietin
|
|
FR2686899B1
(fr)
*
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
DE69724241T2
(de)
|
1996-03-14 |
2004-06-09 |
Genentech, Inc., South San Francisco |
Gdnf-rezeptor und dessen verwendung
|
|
ES2221717T3
(es)
|
1997-12-08 |
2005-01-01 |
Emd Lexigen Research Center Corp. |
Proteinas de fusion heterodimeras utiles para inmunoterapia dirigida e inmunoestimulacion general.
|
|
US7304150B1
(en)
|
1998-10-23 |
2007-12-04 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
|
US6831060B2
(en)
|
1999-05-07 |
2004-12-14 |
Genentech, Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
US6555343B1
(en)
|
1999-05-07 |
2003-04-29 |
Genentech Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
EP1177285A1
(en)
*
|
1999-05-07 |
2002-02-06 |
Genentech, Inc. |
Chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
US6617135B1
(en)
|
1999-08-09 |
2003-09-09 |
Emd Lexigen Research Center Corp. |
Multiple cytokine protein complexes
|
|
CA2391080A1
(en)
|
1999-11-12 |
2001-05-25 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Erythropoietin forms with improved properties
|
|
DK1252192T3
(da)
|
2000-02-11 |
2006-11-20 |
Merck Patent Gmbh |
Forbedring af antistofbaserede fusionsproteiners serumhalveringstid
|
|
JP2003530838A
(ja)
|
2000-04-12 |
2003-10-21 |
ヒューマン ゲノム サイエンシズ インコーポレイテッド |
アルブミン融合タンパク質
|
|
EP2292651A1
(en)
*
|
2000-04-21 |
2011-03-09 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
|
ATE291436T2
(de)
|
2000-05-15 |
2005-04-15 |
Hoffmann La Roche |
Flüssige arzneizubereitung enthaltend ein erythropoietin derivat
|
|
RU2272644C2
(ru)
|
2000-06-29 |
2006-03-27 |
Мерк Патент Гмбх |
Усиление иммунной реакции, медиатором которой является слитый протеин антитело-цитокин, при помощи комбинированного лечения агентами, увеличивающими поглощение иммуноцитокина
|
|
US7078376B1
(en)
*
|
2000-08-11 |
2006-07-18 |
Baxter Healthcare S.A. |
Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
|
|
US7087224B2
(en)
*
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
KR100900176B1
(ko)
|
2001-03-07 |
2009-06-02 |
메르크 파텐트 게엠베하 |
하이브리드 이소타입 항체 부분구조를 포함하는 단백질을위한 발현 기술
|
|
US6992174B2
(en)
|
2001-03-30 |
2006-01-31 |
Emd Lexigen Research Center Corp. |
Reducing the immunogenicity of fusion proteins
|
|
CA2446087C
(en)
|
2001-05-03 |
2013-06-18 |
Stephen D. Gillies |
Recombinant tumor specific antibody and use thereof
|
|
BR0214650A
(pt)
|
2001-12-04 |
2005-05-03 |
Merck Patent Gmbh |
Imunocitoquinas com seletividade modulada
|
|
ES2425738T3
(es)
|
2001-12-21 |
2013-10-17 |
Human Genome Sciences, Inc. |
Proteínas de fusión de la albúmina
|
|
NZ537306A
(en)
*
|
2002-07-01 |
2008-11-28 |
Kenneth S Warren Inst Inc |
Compositions comprising mutein recombinant tissue protective cytokines having one or more amino acid substitutions facilitating transport of a molecule via transcytosis across an endothelial cell barrier
|
|
AU2003246486A1
(en)
*
|
2002-07-19 |
2004-02-09 |
Cangene Corporation |
Pegylated erythropoietic compounds
|
|
JP4494977B2
(ja)
|
2002-12-17 |
2010-06-30 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Gd2に結合するマウス14.18抗体のヒト化抗体(h14.18)およびそのil−2融合タンパク質
|
|
EP1594530A4
(en)
|
2003-01-22 |
2006-10-11 |
Human Genome Sciences Inc |
HYBRID PROTEINS OF ALBUMIN
|
|
JP4980715B2
(ja)
|
2003-05-30 |
2012-07-18 |
ジェミン エックス ファーマシューティカルズ カナダ インコーポレイテッド |
がんまたはウイルス疾患を治療するための三環性複素環化合物、組成物および方法
|
|
WO2005063808A1
(en)
|
2003-12-31 |
2005-07-14 |
Merck Patent Gmbh |
Fc-ERYTHROPOIETIN FUSION PROTEIN WITH IMPROVED PHARMACOKINETICS
|
|
TWI376234B
(en)
|
2005-02-01 |
2012-11-11 |
Msd Oss Bv |
Conjugates of a polypeptide and an oligosaccharide
|
|
EP1888630A2
(en)
*
|
2005-05-24 |
2008-02-20 |
Avestha Gengraine Technologies PVT Ltd |
A recombinant method for production of an erythropoiesis stimulating protein
|
|
US7972810B2
(en)
|
2005-12-08 |
2011-07-05 |
Amgen Inc. |
Production of glycoproteins using manganese
|
|
US7888101B2
(en)
|
2005-12-08 |
2011-02-15 |
Amgen Inc. |
Host cells comprising alpha 1,2 mannosidase and culture methods thereof
|
|
WO2008011158A2
(en)
|
2006-07-21 |
2008-01-24 |
Amgen Inc. |
Method of detecting and/ or measuring hepcidin in a sample
|
|
WO2009043049A2
(en)
|
2007-09-27 |
2009-04-02 |
Amgen Inc. |
Pharmaceutical formulations
|
|
WO2009064838A1
(en)
|
2007-11-15 |
2009-05-22 |
Amgen, Inc. |
Aqueous formulation of erythropoiesis stimulating protein stablised by antioxidants for parenteral administration
|
|
CA2711826C
(en)
|
2008-01-25 |
2018-02-27 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
|
US9315577B2
(en)
|
2008-05-01 |
2016-04-19 |
Amgen Inc. |
Anti-hepcidin antibodies and methods of use
|
|
CN101323630B
(zh)
*
|
2008-07-25 |
2013-06-05 |
中国科学院上海有机化学研究所 |
一种过渡金属络合物、合成方法及其用途
|
|
US8318167B2
(en)
|
2008-11-13 |
2012-11-27 |
The General Hospital Corporation |
Methods and compositions for regulating iron homeostasis by modulation of BMP-6
|
|
EP3009447B1
(en)
|
2009-07-24 |
2018-06-06 |
Dr. Reddy's Laboratories, Ltd. |
Production of erythropoiesis stimulating protein using metal ions
|
|
US8435516B2
(en)
|
2009-10-12 |
2013-05-07 |
Pfizer Inc. |
Cancer treatment
|
|
MX344382B
(es)
|
2009-10-23 |
2016-12-14 |
Amgen Inc * |
Adaptador de vial y sistema.
|
|
HUE026173T2
(en)
|
2010-06-07 |
2016-05-30 |
Amgen Inc |
pharmaceutical Pump
|
|
AU2012236573B2
(en)
|
2011-03-31 |
2016-06-02 |
Amgen Inc. |
Vial adapter and system
|
|
US20140178368A1
(en)
|
2011-04-19 |
2014-06-26 |
Leslie Lynne SHARP |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
TR201905991T4
(tr)
|
2011-04-20 |
2019-05-21 |
Amgen Inc |
Oto enjektör aparatı.
|
|
EP3045188B1
(en)
|
2011-10-14 |
2020-12-23 |
Amgen Inc. |
Injector and method of assembly
|
|
EP2922590B1
(en)
|
2012-11-21 |
2020-02-05 |
Amgen Inc. |
Drug delivery device
|
|
TWI614041B
(zh)
|
2013-03-15 |
2018-02-11 |
安美基公司 |
用於注射器之匣盒
|
|
US10092703B2
(en)
|
2013-03-15 |
2018-10-09 |
Amgen Inc. |
Drug cassette, autoinjector, and autoinjector system
|
|
KR102218494B1
(ko)
|
2013-03-15 |
2021-02-19 |
인트린식 라이프사이언시스, 엘엘씨 |
항-헵시딘 항체 및 그의 용도
|
|
SG11201507417RA
(en)
|
2013-03-15 |
2015-10-29 |
Amgen Inc |
Body contour adaptable autoinjector device
|
|
EP2976117B1
(en)
|
2013-03-22 |
2020-12-30 |
Amgen Inc. |
Injector and method of assembly
|
|
EP3957345B1
(en)
|
2013-10-24 |
2025-12-10 |
Amgen Inc. |
Drug delivery system with temperature-sensitive control
|
|
CA2920894C
(en)
|
2013-10-24 |
2023-03-14 |
Amgen Inc. |
Injector and method of assembly
|
|
US10994112B2
(en)
|
2014-02-05 |
2021-05-04 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
|
MX388536B
(es)
|
2014-05-07 |
2025-03-20 |
Amgen Inc |
Autoinyector con elementos reductores del shock.
|
|
CN106470717B
(zh)
|
2014-06-03 |
2020-09-11 |
安姆根有限公司 |
药物递送系统和使用方法
|
|
AU2015321462B2
(en)
|
2014-09-22 |
2020-04-30 |
Intrinsic Lifesciences Llc |
Humanized anti-hepcidin antibodies and uses thereof
|
|
AU2015332557B2
(en)
|
2014-10-14 |
2020-05-14 |
Amgen Inc. |
Drug injection device with visual and audio indicators
|
|
ES2785311T3
(es)
|
2014-12-19 |
2020-10-06 |
Amgen Inc |
Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario
|
|
EP3848072A1
(en)
|
2014-12-19 |
2021-07-14 |
Amgen Inc. |
Drug delivery device with proximity sensor
|
|
LT3240801T
(lt)
|
2014-12-31 |
2021-02-25 |
Checkmate Pharmaceuticals, Inc. |
Kombinuota navikų imunoterapija
|
|
CA3069716C
(en)
|
2015-02-17 |
2021-11-09 |
Amgen Inc. |
Drug delivery device with vacuum assisted securement and/or feedback
|
|
EP3261690B1
(en)
|
2015-02-27 |
2021-12-15 |
Amgen Inc. |
Drug delivery device having a needle guard mechanism with a tunable threshold of resistance to needle guard movement
|
|
WO2017039786A1
(en)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Syringe assembly adapter for a syringe
|
|
WO2017100501A1
(en)
|
2015-12-09 |
2017-06-15 |
Amgen Inc. |
Auto-injector with signaling cap
|
|
US11154661B2
(en)
|
2016-01-06 |
2021-10-26 |
Amgen Inc. |
Auto-injector with signaling electronics
|
|
WO2017160799A1
(en)
|
2016-03-15 |
2017-09-21 |
Amgen Inc. |
Reducing probability of glass breakage in drug delivery devices
|
|
WO2017189089A1
(en)
|
2016-04-29 |
2017-11-02 |
Amgen Inc. |
Drug delivery device with messaging label
|
|
US11389588B2
(en)
|
2016-05-02 |
2022-07-19 |
Amgen Inc. |
Syringe adapter and guide for filling an on-body injector
|
|
AU2017263558B2
(en)
|
2016-05-13 |
2022-12-22 |
Amgen Inc. |
Vial sleeve assembly
|
|
EP3458988B1
(en)
|
2016-05-16 |
2023-10-18 |
Amgen Inc. |
Data encryption in medical devices with limited computational capability
|
|
WO2017209899A1
(en)
|
2016-06-03 |
2017-12-07 |
Amgen Inc. |
Impact testing apparatuses and methods for drug delivery devices
|
|
WO2018004842A1
(en)
|
2016-07-01 |
2018-01-04 |
Amgen Inc. |
Drug delivery device having minimized risk of component fracture upon impact events
|
|
US20190328965A1
(en)
|
2016-08-17 |
2019-10-31 |
Amgen Inc. |
Drug delivery device with placement detection
|
|
US11202818B2
(en)
|
2016-09-14 |
2021-12-21 |
President And Fellows Of Harvard College |
Methods and compositions for modulating erythropoiesis
|
|
WO2018081234A1
(en)
|
2016-10-25 |
2018-05-03 |
Amgen Inc. |
On-body injector
|
|
JP2020503976A
(ja)
|
2017-01-17 |
2020-02-06 |
アムジエン・インコーポレーテツド |
注入デバイスならびに関連する使用および組立方法
|
|
MX2019009625A
(es)
|
2017-02-17 |
2019-10-09 |
Amgen Inc |
Dispositivo de administracion de farmacos con trayectoria de flujo de fluido esteril y metodo relacionado de ensamblaje.
|
|
EP3582829A1
(en)
|
2017-02-17 |
2019-12-25 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
EP3592403B1
(en)
|
2017-03-06 |
2025-08-20 |
Amgen Inc. |
Drug delivery device with activation prevention feature
|
|
CA3052482A1
(en)
|
2017-03-07 |
2018-09-13 |
Amgen Inc. |
Needle insertion by overpressure
|
|
AU2018230486B2
(en)
|
2017-03-09 |
2023-05-11 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
EP3570871B1
(en)
|
2017-03-20 |
2020-11-18 |
H. Hoffnabb-La Roche Ag |
Method for in vitro glycoengineering of an erythropoiesis stimulating protein
|
|
CN118743804A
(zh)
|
2017-03-28 |
2024-10-08 |
美国安进公司 |
柱塞杆和注射器组件系统以及方法
|
|
CA3066399A1
(en)
|
2017-06-08 |
2018-12-13 |
Amgen Inc. |
Torque driven drug delivery device
|
|
AU2018280054B2
(en)
|
2017-06-08 |
2023-07-13 |
Amgen Inc. |
Syringe assembly for a drug delivery device and method of assembly
|
|
AU2018288604B2
(en)
|
2017-06-22 |
2023-12-21 |
Amgen Inc. |
Device activation impact/shock reduction
|
|
MA49461A
(fr)
|
2017-06-23 |
2020-04-29 |
Amgen Inc |
Dispositif électronique d'administration de médicament comprenant un bouchon activé par un ensemble commutateur
|
|
MA49562A
(fr)
|
2017-07-14 |
2020-05-20 |
Amgen Inc |
Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion
|
|
US11672733B2
(en)
|
2017-07-21 |
2023-06-13 |
Amgen Inc. |
Gas permeable sealing member for drug container and methods of assembly
|
|
US11484648B2
(en)
|
2017-07-25 |
2022-11-01 |
Amgen Inc. |
Drug delivery device with container access system and related method of assembly
|
|
JP2020528296A
(ja)
|
2017-07-25 |
2020-09-24 |
アムジエン・インコーポレーテツド |
ギヤモジュールを有する薬物送達デバイス及び関連する組立方法
|
|
WO2019032482A2
(en)
|
2017-08-09 |
2019-02-14 |
Amgen Inc. |
HYDRAULIC-PNEUMATIC PRESSURE CHAMBER DELIVERY SYSTEM
|
|
WO2019036181A1
(en)
|
2017-08-18 |
2019-02-21 |
Amgen Inc. |
BODY INJECTOR WITH STERILE ADHESIVE PATCH
|
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
|
ES2939292T3
(es)
|
2017-10-04 |
2023-04-20 |
Amgen Inc |
Adaptador de flujo para dispositivo de administración de fármacos
|
|
EP4257164A3
(en)
|
2017-10-06 |
2024-01-17 |
Amgen Inc. |
Drug delivery device with interlock assembly and related method of assembly
|
|
EP3694578B1
(en)
|
2017-10-09 |
2025-09-24 |
Amgen Inc. |
Drug delivery device with drive assembly and related method of assembly
|
|
MA50528A
(fr)
|
2017-11-03 |
2020-09-09 |
Amgen Inc |
Systèmes et approches pour stériliser un dispositif d'administration de médicament
|
|
WO2019089178A1
(en)
|
2017-11-06 |
2019-05-09 |
Amgen Inc. |
Drug delivery device with placement and flow sensing
|
|
US12053618B2
(en)
|
2017-11-06 |
2024-08-06 |
Amgen Inc. |
Fill-finish assemblies and related methods
|
|
IL319987A
(en)
|
2017-11-10 |
2025-06-01 |
Amgen Inc |
Plungers for drug delivery devices
|
|
JP7747438B2
(ja)
|
2017-11-16 |
2025-10-01 |
アムジエン・インコーポレーテツド |
失速及び終点検出を有するオートインジェクタ
|
|
SG11202003004RA
(en)
|
2017-11-16 |
2020-04-29 |
Amgen Inc |
Door latch mechanism for drug delivery device
|
|
US12246031B2
(en)
|
2018-02-13 |
2025-03-11 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
MX2020010410A
(es)
|
2018-04-09 |
2021-01-15 |
Checkmate Pharmaceuticals |
Empaquetado de oligonucleotidos en particulas similares a virus.
|
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
|
US12115360B2
(en)
|
2018-07-24 |
2024-10-15 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
|
MX2021000749A
(es)
|
2018-07-24 |
2021-03-29 |
Amgen Inc |
Dispositivos de suministro para administrar farmacos.
|
|
US12303677B2
(en)
|
2018-07-24 |
2025-05-20 |
Amgen Inc. |
Hybrid drug delivery devices with optional grip portion and related method of preparation
|
|
US12042645B2
(en)
|
2018-07-24 |
2024-07-23 |
Amgen Inc. |
Delivery devices for administering drugs
|
|
EP3829692A1
(en)
|
2018-07-31 |
2021-06-09 |
Amgen Inc. |
Fluid path assembly for a drug delivery device
|
|
US20210346601A1
(en)
|
2018-09-24 |
2021-11-11 |
Amgen Inc. |
Interventional dosing systems and methods
|
|
EP3856283A1
(en)
|
2018-09-28 |
2021-08-04 |
Amgen Inc. |
Muscle wire escapement activation assembly for a drug delivery device
|
|
AU2019352616B2
(en)
|
2018-10-02 |
2024-10-10 |
Amgen Inc. |
Injection systems for drug delivery with internal force transmission
|
|
US12151089B2
(en)
|
2018-10-05 |
2024-11-26 |
Amgen Inc. |
Drug delivery device having dose indicator
|
|
JP2022504805A
(ja)
|
2018-10-15 |
2022-01-13 |
アムジエン・インコーポレーテツド |
薬物送達デバイスのプラットフォーム式組み立てプロセス
|
|
SG11202103800RA
(en)
|
2018-10-15 |
2021-05-28 |
Amgen Inc |
Drug delivery device having damping mechanism
|
|
TWI831847B
(zh)
|
2018-11-01 |
2024-02-11 |
美商安進公司 |
部分針頭縮回之藥物遞送裝置及其操作方法
|
|
US11213620B2
(en)
|
2018-11-01 |
2022-01-04 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
|
AU2019370159B2
(en)
|
2018-11-01 |
2025-05-29 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
|
JP7510952B2
(ja)
|
2019-04-24 |
2024-07-04 |
アムジエン・インコーポレーテツド |
シリンジ滅菌確認アセンブリ及び方法
|
|
JP7608439B2
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Amgen Inc. |
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