ATE355303T1 - Methoden und zusammensetzungen zur prävention und behandlung der anämie - Google Patents

Methoden und zusammensetzungen zur prävention und behandlung der anämie

Info

Publication number
ATE355303T1
ATE355303T1 AT99955046T AT99955046T ATE355303T1 AT E355303 T1 ATE355303 T1 AT E355303T1 AT 99955046 T AT99955046 T AT 99955046T AT 99955046 T AT99955046 T AT 99955046T AT E355303 T1 ATE355303 T1 AT E355303T1
Authority
AT
Austria
Prior art keywords
anemia
prevention
compositions
treatment
methods
Prior art date
Application number
AT99955046T
Other languages
English (en)
Inventor
Joan C Egrie
Steven G Elliott
Jeffrey K Brown
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22651968&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE355303(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE355303T1 publication Critical patent/ATE355303T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT99955046T 1998-10-23 1999-10-18 Methoden und zusammensetzungen zur prävention und behandlung der anämie ATE355303T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17829298A 1998-10-23 1998-10-23

Publications (1)

Publication Number Publication Date
ATE355303T1 true ATE355303T1 (de) 2006-03-15

Family

ID=22651968

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99955046T ATE355303T1 (de) 1998-10-23 1999-10-18 Methoden und zusammensetzungen zur prävention und behandlung der anämie
AT07004087T ATE477270T1 (de) 1998-10-23 1999-10-18 Verfahren und zusammensetzungen zur prävention und behandlung von anämie

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT07004087T ATE477270T1 (de) 1998-10-23 1999-10-18 Verfahren und zusammensetzungen zur prävention und behandlung von anämie

Country Status (19)

Country Link
EP (2) EP1123313B2 (de)
JP (2) JP4809977B2 (de)
KR (1) KR20010075661A (de)
CN (2) CN1346369B (de)
AR (1) AR020848A1 (de)
AT (2) ATE355303T1 (de)
AU (1) AU774989B2 (de)
CA (1) CA2345882C (de)
CY (2) CY1107584T1 (de)
DE (2) DE69942680D1 (de)
DK (2) DK1813624T3 (de)
ES (2) ES2283139T5 (de)
HK (1) HK1040944B (de)
HU (1) HU228492B1 (de)
IL (2) IL142334A (de)
PT (2) PT1123313E (de)
SI (2) SI1123313T1 (de)
TW (1) TWI234583B (de)
WO (1) WO2000024893A2 (de)

Families Citing this family (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US6504007B1 (en) 1996-03-14 2003-01-07 Genentech, Inc. GDNF receptor
ES2221717T3 (es) 1997-12-08 2005-01-01 Emd Lexigen Research Center Corp. Proteinas de fusion heterodimeras utiles para inmunoterapia dirigida e inmunoestimulacion general.
US7304150B1 (en) 1998-10-23 2007-12-04 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
US6831060B2 (en) 1999-05-07 2004-12-14 Genentech, Inc. Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
MXPA01011264A (es) * 1999-05-07 2002-07-02 Genentech Inc Nuevos polipeptidos de eritropoyetina de chimpance (chepo) y aciodos nucleicos que codifican los mismos.
US6555343B1 (en) 1999-05-07 2003-04-29 Genentech Inc. Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
US7067110B1 (en) 1999-07-21 2006-06-27 Emd Lexigen Research Center Corp. Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
RU2263118C2 (ru) 1999-08-09 2005-10-27 Лексиген Фармасьютикэлс Корп. Комплексы антител с несколькими цитокинами
JP2003514552A (ja) 1999-11-12 2003-04-22 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 改善された性質を有するエリトロポエチンの形態
ATE336514T1 (de) 2000-02-11 2006-09-15 Merck Patent Gmbh Steigerung der zirkulierenden halbwertzeit von auf antikörpern basierenden fusionsproteinen
EP1803730A1 (de) 2000-04-12 2007-07-04 Human Genome Sciences, Inc. Albuminfusionsproteine
EP1274728B1 (de) * 2000-04-21 2008-05-14 Amgen Inc. Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie
DK1311285T4 (en) 2000-05-15 2017-07-24 Hoffmann La Roche Liquid pharmaceutical composition containing an erythropoietin derivative
US7517526B2 (en) 2000-06-29 2009-04-14 Merck Patent Gmbh Enhancement of antibody-cytokine fusion protein mediated immune responses by combined treatment with immunocytokine uptake enhancing agents
US7078376B1 (en) 2000-08-11 2006-07-18 Baxter Healthcare S.A. Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
US7087224B2 (en) * 2000-10-31 2006-08-08 Amgen Inc. Method of treating anemia by administering IL-1ra
PT1366067E (pt) 2001-03-07 2012-11-29 Merck Patent Gmbh Tecnologia de expressão para proteínas contendo uma unidade de anticorpo de isotipo híbrido
US6992174B2 (en) 2001-03-30 2006-01-31 Emd Lexigen Research Center Corp. Reducing the immunogenicity of fusion proteins
DE60239454D1 (de) 2001-05-03 2011-04-28 Merck Patent Gmbh Rekombinanter, tumorspezifischer antikörper und dessen verwendung
AU2002357784B2 (en) 2001-12-04 2008-07-31 Merck Patent Gmbh Immunocytokines with modulated selectivity
EP1997829A1 (de) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin Fusionsproteine
AU2003251770B9 (en) * 2002-07-01 2009-06-04 H. Lundbeck A/S Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
AU2003246486A1 (en) * 2002-07-19 2004-02-09 Cangene Corporation Pegylated erythropoietic compounds
ES2346205T3 (es) 2002-12-17 2010-10-13 Merck Patent Gmbh Anticuerpo humanizado (h14.18) del anticurpo 14.18 de raton que se enlaza con gd2 y su fusion con la il-2.
CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
EP1644363B1 (de) 2003-05-30 2012-02-22 Gemin X Pharmaceuticals Canada Inc. Triheterocyclische verbindungen, zusammensetzungen, und verfahren zur behandlung von krebs
WO2005063808A1 (en) 2003-12-31 2005-07-14 Merck Patent Gmbh Fc-ERYTHROPOIETIN FUSION PROTEIN WITH IMPROVED PHARMACOKINETICS
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
RU2007147422A (ru) * 2005-05-24 2009-06-27 Эйвестаджен Лимитед,In (In) Способ рекомбинантного получения стимулирующего эритропоэз белка
EP1957637B1 (de) 2005-12-08 2013-08-14 Amgen, Inc. Verbesserte wirtszellen und kulturverfahren
EP4155385A1 (de) 2005-12-08 2023-03-29 Amgen Inc. Verbesserte herstellung von glykoproteinen unter verwendung von mangan
MX2009000685A (es) 2006-07-21 2009-01-30 Amgen Inc Metodo para detectar y/o cuantificar hepcidina en una muestra.
WO2009043049A2 (en) 2007-09-27 2009-04-02 Amgen Inc. Pharmaceutical formulations
ES2962777T3 (es) 2007-11-15 2024-03-21 Amgen Inc Formulación acuosa de anticuerpos estabilizada por antioxidantes para la administración parenteral
CA2711826C (en) 2008-01-25 2018-02-27 Amgen Inc. Ferroportin antibodies and methods of use
US9315577B2 (en) 2008-05-01 2016-04-19 Amgen Inc. Anti-hepcidin antibodies and methods of use
CN101323630B (zh) * 2008-07-25 2013-06-05 中国科学院上海有机化学研究所 一种过渡金属络合物、合成方法及其用途
CA3019967A1 (en) 2008-11-13 2010-05-20 The General Hospital Corporation Methods and compositions for regulating iron homeostasis by modulation of bmp-6
EP2456871B1 (de) 2009-07-24 2016-09-07 Dr. Reddy's Laboratories, Ltd. Herstellung erythropoese-stimulierender proteine mithilfe von metallionen
AU2010308030B2 (en) 2009-10-12 2014-05-29 Pfizer Inc. Cancer treatment
MX344382B (es) 2009-10-23 2016-12-14 Amgen Inc * Adaptador de vial y sistema.
PT2575935E (pt) 2010-06-07 2015-10-20 Amgen Inc Dispositivo de administração de medicamento
EP2691065B1 (de) 2011-03-31 2017-03-01 Amgen Inc. Fläschchenadapter und system damit
TR201905909T4 (tr) 2011-04-19 2019-05-21 Pfizer Kanser tedavisi için anti-4-1bb antikorlarının ve adcc indükleyici antikorların kombinasyonları.
US10092706B2 (en) 2011-04-20 2018-10-09 Amgen Inc. Autoinjector apparatus
PL3045187T3 (pl) 2011-10-14 2019-09-30 Amgen Inc. Wstrzykiwacz i sposób montażu
SI3081249T1 (sl) 2012-11-21 2021-03-31 Amgen Inc. Naprava za dajanje zdravila
CN110041427B (zh) 2013-03-15 2023-05-23 本质生命科学有限公司 抗铁调素抗体及其用途
SG11201507417RA (en) 2013-03-15 2015-10-29 Amgen Inc Body contour adaptable autoinjector device
TWI580451B (zh) 2013-03-15 2017-05-01 安美基公司 用於注射器之匣盒及使用具有自動注射器及匣盒之自動注射器設備之方法
CA2904661C (en) 2013-03-15 2022-03-15 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
EP2976117B1 (de) 2013-03-22 2020-12-30 Amgen Inc. Injektor und verfahren zur montage
AU2014340174B2 (en) 2013-10-24 2019-09-12 Amgen Inc. Drug delivery system with temperature-sensitive control
EP3060275B1 (de) 2013-10-24 2019-07-03 Amgen Inc. Injektor und verfahren zur montage
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
EP3785749B1 (de) 2014-05-07 2026-04-01 Amgen Inc. Autoinjektor mit stossabsorbierenden elementen
EP4036924A1 (de) 2014-06-03 2022-08-03 Amgen, Inc Vorrichtungen und verfahren zur unterstützung eines benutzers einer arzneimittelabgabevorrichtung
NZ730186A (en) 2014-09-22 2020-04-24 Intrinsic Lifesciences Llc Humanized anti-hepcidin antibodies and uses thereof
WO2016061220A2 (en) 2014-10-14 2016-04-21 Amgen Inc. Drug injection device with visual and audio indicators
US10799630B2 (en) 2014-12-19 2020-10-13 Amgen Inc. Drug delivery device with proximity sensor
EP3689394A1 (de) 2014-12-19 2020-08-05 Amgen Inc. Arzneimittelabgabevorrichtung mit live-knopf oder benutzerschnittstellenfeld
CN107428813B (zh) 2014-12-31 2021-08-03 查克美特制药公司 组合肿瘤免疫疗法
WO2016133947A1 (en) 2015-02-17 2016-08-25 Amgen Inc. Drug delivery device with vacuum assisted securement and/or feedback
EP3981450A1 (de) 2015-02-27 2022-04-13 Amgen, Inc Arzneimittelabgabevorrichtung mit nadelschutzmechanismus mit abstimmbarem widerstandsschwellwert gegenüber der bewegung des nadelschutzes
WO2017039786A1 (en) 2015-09-02 2017-03-09 Amgen Inc. Syringe assembly adapter for a syringe
US11351308B2 (en) 2015-12-09 2022-06-07 Amgen Inc. Auto-injector with signaling cap
WO2017120178A1 (en) 2016-01-06 2017-07-13 Amgen Inc. Auto-injector with signaling electronics
EP3721922B1 (de) 2016-03-15 2022-05-04 Amgen Inc. Verringerung der wahrscheinlichkeit auf glasbruch in arzneimittelabgabevorrichtungen
US11541168B2 (en) 2016-04-29 2023-01-03 Amgen Inc. Drug delivery device with messaging label
US11389588B2 (en) 2016-05-02 2022-07-19 Amgen Inc. Syringe adapter and guide for filling an on-body injector
AU2017263558B2 (en) 2016-05-13 2022-12-22 Amgen Inc. Vial sleeve assembly
US11238150B2 (en) 2016-05-16 2022-02-01 Amgen Inc. Data encryption in medical devices with limited computational capability
US11541176B2 (en) 2016-06-03 2023-01-03 Amgen Inc. Impact testing apparatuses and methods for drug delivery devices
US11285266B2 (en) 2016-07-01 2022-03-29 Amgen Inc. Drug delivery device having minimized risk of component fracture upon impact events
US20190328965A1 (en) 2016-08-17 2019-10-31 Amgen Inc. Drug delivery device with placement detection
WO2018053142A2 (en) * 2016-09-14 2018-03-22 President And Fellows Of Harvard College Methods and compositions for modulating erythropoiesis
WO2018081234A1 (en) 2016-10-25 2018-05-03 Amgen Inc. On-body injector
CA3049780A1 (en) 2017-01-17 2018-07-26 Amgen Inc. Injection devices and related methods of use and assembly
EP3582825A1 (de) 2017-02-17 2019-12-25 Amgen Inc. Wirkstofffreisetzungsvorrichtung mit steriler fluidströmung und zugehöriges verfahren zur montage
JP7280189B2 (ja) 2017-02-17 2023-05-23 アムジエン・インコーポレーテツド 薬物送達装置用の挿入機構
MX2019010544A (es) 2017-03-06 2019-10-21 Amgen Inc Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion.
KR102627069B1 (ko) 2017-03-07 2024-01-18 암겐 인코포레이티드 과압에 의한 바늘 삽입
KR102893480B1 (ko) 2017-03-09 2025-11-28 암겐 인코포레이티드 약물 전달 장치용 삽입 메커니즘
JP2020511499A (ja) 2017-03-20 2020-04-16 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 赤血球生成刺激タンパク質のインビトロでの糖鎖改変のための方法
BR112019020053B1 (pt) 2017-03-28 2023-10-10 Amgen Inc Máquina para acoplar uma haste de êmbolo a um conjunto de seringa e método de utilização da referida máquina
MX2019014615A (es) 2017-06-08 2020-02-07 Amgen Inc Dispositivo de administracion de farmacos accionado por par de torsion.
WO2018226515A1 (en) 2017-06-08 2018-12-13 Amgen Inc. Syringe assembly for a drug delivery device and method of assembly
AU2018288604B2 (en) 2017-06-22 2023-12-21 Amgen Inc. Device activation impact/shock reduction
AU2018290302B2 (en) 2017-06-23 2024-02-29 Amgen Inc. Electronic drug delivery device comprising a cap activated by a switch assembly
MA49562A (fr) 2017-07-14 2020-05-20 Amgen Inc Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion
EP4292576A3 (de) 2017-07-21 2024-01-17 Amgen Inc. Gasdurchlässiges dichtungselement für arzneimittelbehälter und verfahren zur montage
WO2019022950A1 (en) 2017-07-25 2019-01-31 Amgen Inc. DRUG DELIVERY DEVICE WITH CONTAINER ACCESS SYSTEM AND ASSEMBLY METHOD THEREOF
WO2019022951A1 (en) 2017-07-25 2019-01-31 Amgen Inc. DRUG DELIVERY DEVICE WITH GEAR MODULE AND ASSEMBLY METHOD THEREOF
EP3664863A2 (de) 2017-08-09 2020-06-17 Amgen Inc. Hydraulisch-pneumatisches druckkammer-arzneimittelabgabesystem
US11077246B2 (en) 2017-08-18 2021-08-03 Amgen Inc. Wearable injector with sterile adhesive patch
US11103636B2 (en) 2017-08-22 2021-08-31 Amgen Inc. Needle insertion mechanism for drug delivery device
ES2939292T3 (es) 2017-10-04 2023-04-20 Amgen Inc Adaptador de flujo para dispositivo de administración de fármacos
EP4257164A3 (de) 2017-10-06 2024-01-17 Amgen Inc. Arzneimittelabgabevorrichtung mit verriegelungsvorrichtung und zugehöriges montageverfahren
MA50348A (fr) 2017-10-09 2020-08-19 Amgen Inc Dispositif d'administration de médicament comprenant un ensemble d'entraînement et procédé d'assemblage associé
EP3703779B1 (de) 2017-11-03 2026-01-28 Amgen Inc. Systeme und vorgehen zur sterilisation einer arzneimittelabgabevorrichtung
US12053618B2 (en) 2017-11-06 2024-08-06 Amgen Inc. Fill-finish assemblies and related methods
MA50553A (fr) 2017-11-06 2020-09-16 Amgen Inc Dispositif d'administration de médicament avec détection de positionnement et de débit
IL273637B2 (en) 2017-11-10 2025-09-01 Amgen Inc Pistons for drug delivery devices
AU2018368340B2 (en) 2017-11-16 2024-03-07 Amgen Inc. Door latch mechanism for drug delivery device
CN111263651B (zh) 2017-11-16 2022-06-17 安进公司 具有停顿和终点检测的自动注射器
EP3752194A4 (de) 2018-02-13 2022-03-16 Checkmate Pharmaceuticals, Inc. Zusammensetzungen und verfahren für die tumorimmuntherapie
KR102890791B1 (ko) 2018-04-09 2025-11-24 체크메이트 파마슈티칼스, 인크. 바이러스-유사 입자 내로의 올리고뉴클레오타이드의 포장
US10835685B2 (en) 2018-05-30 2020-11-17 Amgen Inc. Thermal spring release mechanism for a drug delivery device
US11083840B2 (en) 2018-06-01 2021-08-10 Amgen Inc. Modular fluid path assemblies for drug delivery devices
WO2020023336A1 (en) 2018-07-24 2020-01-30 Amgen Inc. Hybrid drug delivery devices with grip portion
WO2020023451A1 (en) 2018-07-24 2020-01-30 Amgen Inc. Delivery devices for administering drugs
WO2020023444A1 (en) 2018-07-24 2020-01-30 Amgen Inc. Delivery devices for administering drugs
WO2020023220A1 (en) 2018-07-24 2020-01-30 Amgen Inc. Hybrid drug delivery devices with tacky skin attachment portion and related method of preparation
CA3103105A1 (en) 2018-07-31 2020-02-06 Amgen Inc. Fluid path assembly for a drug delivery device
JP2022500095A (ja) 2018-09-24 2022-01-04 アムジエン・インコーポレーテツド インターベンション投薬システム及び方法
IL281469B2 (en) 2018-09-28 2024-08-01 Amgen Inc Muscle wire escapement activation assembly for a drug delivery device
MA53815A (fr) 2018-10-02 2022-01-05 Amgen Inc Systèmes d'injection pour administration de médicament avec transmission de force interne
AU2019355979B2 (en) 2018-10-05 2024-12-05 Amgen Inc. Drug delivery device having dose indicator
TWI846741B (zh) 2018-10-15 2024-07-01 美商安進公司 用於藥物遞送裝置之平台組裝方法
JP7719714B2 (ja) 2018-10-15 2025-08-06 アムジエン・インコーポレーテツド ダンピング機構を有する薬物送達装置
TWI831847B (zh) 2018-11-01 2024-02-11 美商安進公司 部分針頭縮回之藥物遞送裝置及其操作方法
CA3113076A1 (en) 2018-11-01 2020-05-07 Amgen Inc. Drug delivery devices with partial drug delivery member retraction
ES3010833T3 (en) 2018-11-01 2025-04-04 Amgen Inc Drug delivery devices with partial drug delivery member retraction
JP7510952B2 (ja) 2019-04-24 2024-07-04 アムジエン・インコーポレーテツド シリンジ滅菌確認アセンブリ及び方法
CA3148261A1 (en) 2019-08-23 2021-03-04 Amgen Inc. Drug delivery device with configurable needle shield engagement components and related methods
US20240208680A1 (en) 2021-05-21 2024-06-27 Amgen Inc. Method of optimizing a filling recipe for a drug container
WO2023209074A1 (en) 2022-04-28 2023-11-02 Institut National de la Santé et de la Recherche Médicale Methods of restoring erythropoiesis in patients suffering from a sf3b1 mutant myelodysplastic syndrome by correcting coasy mis-splicing
KR20250099137A (ko) 2022-11-02 2025-07-01 에프. 호프만-라 로슈 아게 당단백질 조성물의 생산 방법
WO2026030152A1 (en) 2024-07-29 2026-02-05 Amgen Inc. System and method for assessing transferability of a fill recipe

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954437A (en) 1986-09-15 1990-09-04 Integrated Genetics, Inc. Cell encoding recombinant human erythropoietin
KR100263845B1 (ko) * 1989-10-13 2000-08-16 스튜어트 엘.왓트 에리트로포이에틴 동형체와 그의 제조방법 및 그를 포함하는제약학적 조성물
US5716644A (en) * 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
CN1057534C (zh) * 1993-08-17 2000-10-18 柯瑞英-艾格公司 促红细胞生成素类似物
US5541458A (en) * 1994-11-14 1996-07-30 Hewlett-Packard Company Power supply for timed residual power after turn off
DE19535571A1 (de) * 1995-09-14 1997-03-20 Boehringer Mannheim Gmbh Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten
DE69726571T2 (de) * 1997-09-01 2004-11-04 Aventis Pharma Deutschland Gmbh Rekombinantes humanes Erythropoietin mit vorteilhaftem Glykosylierungsmuster

Also Published As

Publication number Publication date
CN1346369A (zh) 2002-04-24
DE69935345T2 (de) 2007-07-05
SI1123313T1 (sl) 2007-06-30
EP1123313A2 (de) 2001-08-16
EP1123313B1 (de) 2007-02-28
SI1813624T1 (sl) 2010-12-31
CN101703760A (zh) 2010-05-12
CA2345882C (en) 2011-02-01
DK1813624T3 (da) 2010-11-22
WO2000024893A2 (en) 2000-05-04
JP5558213B2 (ja) 2014-07-23
CA2345882A1 (en) 2000-05-04
DK1123313T3 (da) 2007-06-18
ATE477270T1 (de) 2010-08-15
HUP0103920A2 (hu) 2002-02-28
ES2283139T3 (es) 2007-10-16
KR20010075661A (ko) 2001-08-09
EP1123313B2 (de) 2018-01-10
ES2347884T3 (es) 2010-11-22
HK1040944B (en) 2007-09-07
PT1123313E (pt) 2007-04-30
DE69935345T3 (de) 2018-03-01
ES2283139T5 (es) 2018-03-05
HUP0103920A3 (en) 2006-04-28
IL142334A (en) 2010-04-29
JP2002528465A (ja) 2002-09-03
EP1813624B1 (de) 2010-08-11
CY1110801T1 (el) 2015-06-10
CN1346369B (zh) 2011-09-28
JP2010248207A (ja) 2010-11-04
CY1107584T1 (el) 2013-03-13
DE69942680D1 (de) 2010-09-23
AR020848A1 (es) 2002-05-29
PT1813624E (pt) 2010-10-27
DE69935345D1 (de) 2007-04-12
WO2000024893A3 (en) 2000-09-14
HU228492B1 (en) 2013-03-28
IL196645A (en) 2012-08-30
HK1040944A1 (en) 2002-06-28
JP4809977B2 (ja) 2011-11-09
AU1124100A (en) 2000-05-15
AU774989B2 (en) 2004-07-15
EP1813624A1 (de) 2007-08-01
TWI234583B (en) 2005-06-21

Similar Documents

Publication Publication Date Title
ATE355303T1 (de) Methoden und zusammensetzungen zur prävention und behandlung der anämie
DE60227095D1 (de) Zusammensetzungen und verfahren zur behandlung von abgebundenem gips
ATE257385T1 (de) Zusammensetzungen und verfahren zur behandlung des erhöhten augenindruckes
EP1469871A4 (de) Verfahren zur behandlung von apoptose und zusammensetzungen dafür
ATE179610T1 (de) Zusammensetzung zur behandlung ovarieller östrogenabhängiger krankheiten
DE69836915D1 (de) Mundpflegemittel zur behandlung von übelriechendem atem
ATE308997T1 (de) Mittel zur behandlung von erkrankungen der speiseröhre
DE69928542D1 (de) 5ht2-agoniste zur behandlung des glaukoms
DE69828620D1 (de) Verfahren und zusammensetzungen zur vorbeugung und behandlung der chronologischer alterung der menschliches haut
ATE349537T1 (de) Verbindung und verfahren zur bekämpfung und/oder behandlung der allergie
ATE328573T1 (de) Behandlung und zusammensetzungen zur erzielung eines hautalterungsschutzes durch corneum protease aktivatoren
EP1432431A4 (de) Verfahren und zusammensetzungen zur modulierung der wirkung des interleukin-21-rezeptors
DE69807115D1 (de) Angiostatische verbindungen und zusammensetzungen zur behandlung des glc1a glaukoms
DE60232597D1 (de) Verfahren zur bleichung von zähnen; zahnbleichzusammensetzung und zahnbleichset
DE69806801D1 (de) Galenische präparation zur prävention und behandlung von hepatokarzinomen
EP1109548A4 (de) Zusammensetzungen und verfahren zur behandlung und vorbeugung von knochenkrankheiten unter verwendung von tocotrienole
ATE415163T1 (de) Verfahren und zusammensetzungen zur behandlung von augenerkrankungen
DE69905214D1 (de) Mittel zur Behandlung der Osteoporose
DE60002226D1 (de) Zusammensetzung zur vorbeugung und/oder behandlung von kreislaufstörungen, enthaltend l-carnitin derivate und ginkgo biloba extrakte
DE69900339D1 (de) Mittel und Verfahren zur Behandlung von Kunstfasern
DE69825319D1 (de) Präparat zur vorbeugung und behandlung von entzündungen
ATE443060T1 (de) Benzoägüchinolinderivate zur behandlung von glaucom und kurzsichtigkeit
DE69924379D1 (de) Verbindungen und zubereitungen zur behandlung der ischämie des gewebes
DE69924676D1 (de) Rotor zur Behandlung von geschmolzenem Metall
ATE274044T1 (de) Zusammensetzungen zur behandlung von gewebe

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1123313

Country of ref document: EP