|
US5703058A
(en)
*
|
1995-01-27 |
1997-12-30 |
Emory University |
Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
|
|
EP2390257A1
(en)
*
|
1998-02-25 |
2011-11-30 |
Emory University |
2'-fluoronucleosides
|
|
CN1427722A
(zh)
|
2000-02-18 |
2003-07-02 |
希拉生物化学股份有限公司 |
用核苷类似物治疗或预防黄病毒感染的方法
|
|
WO2001079246A2
(en)
|
2000-04-13 |
2001-10-25 |
Pharmasset, Ltd. |
3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections
|
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
PL359169A1
(en)
*
|
2000-05-26 |
2004-08-23 |
Idenix (Cayman) Limited |
Methods and compositions for treating flaviviruses and pestiviruses
|
|
FR2810319A1
(fr)
*
|
2000-06-15 |
2001-12-21 |
Ppg Sipsy |
Composes alpha-phenylsulfinyl-alpha-halogeno-butyrolactone et halogeno-2-buten-2-olide-4 utiles pour la preparation de composes halogeno-2-oxymethyl-4-furanone (4h)
|
|
US20030008841A1
(en)
*
|
2000-08-30 |
2003-01-09 |
Rene Devos |
Anti-HCV nucleoside derivatives
|
|
CN101862345B
(zh)
*
|
2000-10-18 |
2014-06-04 |
吉利德制药有限责任公司 |
用于治疗病毒感染和异常细胞增殖的修饰核苷类化合物
|
|
EA007491B1
(ru)
*
|
2001-01-22 |
2006-10-27 |
Мерк Энд Ко., Инк. |
Производные нуклеозидов в качестве ингибиторов рнк-зависимой рнк вирусной полимеразы
|
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
WO2002062123A2
(en)
*
|
2001-02-06 |
2002-08-15 |
Yale University |
Novel compounds and methods for inhibiting/treating hiv infections and aids related symptoms
|
|
IL157478A0
(en)
|
2001-03-01 |
2004-03-28 |
Pharmasset Ltd |
Method for the synthesis of 2', 3'-didehydronucleosides
|
|
WO2002069903A2
(en)
*
|
2001-03-06 |
2002-09-12 |
Biocryst Pharmaceuticals, Inc. |
Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
|
GB0112617D0
(en)
*
|
2001-05-23 |
2001-07-18 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
|
GB0114286D0
(en)
*
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
JP2005503358A
(ja)
|
2001-06-22 |
2005-02-03 |
フアーマセツト・リミテツド |
β−2’−または3’−ハロヌクレオシド
|
|
US7138376B2
(en)
|
2001-09-28 |
2006-11-21 |
Idenix Pharmaceuticals, Inc. |
Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides
|
|
US7049303B2
(en)
|
2001-11-07 |
2006-05-23 |
Medical Research Council |
Inhibition of viruses
|
|
WO2003063771A2
(en)
|
2001-12-14 |
2003-08-07 |
Pharmasset Ltd. |
N4-acylcytosine nucleosides for treatment of viral iinfections
|
|
CN1646534A
(zh)
*
|
2002-02-14 |
2005-07-27 |
法玛塞特有限公司 |
修饰的氟化核苷类似物
|
|
US7608600B2
(en)
*
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
NZ537662A
(en)
*
|
2002-06-28 |
2007-10-26 |
Idenix Cayman Ltd |
2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
|
TW200500374A
(en)
*
|
2002-06-28 |
2005-01-01 |
Idenlx Cayman Ltd |
2' and 3' -nucleoside produrgs for treating flavivridae infections
|
|
CA2489552A1
(en)
|
2002-06-28 |
2004-01-08 |
Idenix (Cayman) Limited |
2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
|
JP2006507235A
(ja)
|
2002-08-01 |
2006-03-02 |
フアーマセツト・インコーポレイテツド |
フラビウイルス科ウイルス感染治療のためのビシクロ[4.2.1]ノナン系を有する化合物
|
|
US20040067877A1
(en)
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
|
US6884880B2
(en)
*
|
2002-08-21 |
2005-04-26 |
Ash Stevens, Inc. |
Process for the preparation of 9-β-anomeric nucleoside analogs
|
|
US7902203B2
(en)
*
|
2002-11-01 |
2011-03-08 |
Abbott Laboratories, Inc. |
Anti-infective agents
|
|
SI1576138T1
(sl)
|
2002-11-15 |
2017-07-31 |
Idenix Pharmaceuticals Llc |
2'-metil nukleozidi v kombinaciji z interferon in flaviviridae mutacijo
|
|
ES2470771T3
(es)
*
|
2002-12-12 |
2014-06-24 |
Idenix Pharmaceuticals, Inc |
Procedimiento para la producción de nucle�sidos ramificados en 2'
|
|
EP1575971A4
(en)
*
|
2002-12-23 |
2008-03-05 |
Idenix Cayman Ltd |
PROCESS FOR THE PREPARATION OF 3-NUCLEOSIDE PRODRUGS
|
|
RU2005133093A
(ru)
*
|
2003-03-28 |
2006-07-27 |
Фармассет, Инк. (Us) |
Соединения для лечения флавивирусных инфекций
|
|
CN1812995A
(zh)
*
|
2003-04-28 |
2006-08-02 |
艾登尼科斯(开曼)有限公司 |
工业化规模的核苷合成
|
|
PT1633766T
(pt)
|
2003-05-30 |
2019-06-04 |
Gilead Pharmasset Llc |
Análogos de nucleósido fluorado modificado
|
|
EP2157095A3
(en)
|
2003-06-30 |
2010-09-08 |
Novartis AG |
Synthesis of beta-L-2-Deoxy nucleosides
|
|
EP1658302B1
(en)
*
|
2003-07-25 |
2010-08-25 |
IDENIX Pharmaceuticals, Inc. |
Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis c
|
|
WO2005018330A1
(en)
*
|
2003-08-18 |
2005-03-03 |
Pharmasset, Inc. |
Dosing regimen for flaviviridae therapy
|
|
BRPI0414019A
(pt)
|
2003-08-27 |
2006-10-24 |
Biota Inc |
nucleosìdios ou nucleotìdio tricìclicos como agentes terapêuticos
|
|
EP1668023A1
(de)
*
|
2003-09-12 |
2006-06-14 |
Max-Delbrück-Centrum Für Molekulare Medizin |
B-l-nucleoside und ihre verwendung als pharmazeutische mittel zur behandlung viraler erkrankungen
|
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
|
KR100839394B1
(ko)
*
|
2004-06-09 |
2008-06-20 |
에프. 호프만-라 로슈 아게 |
피라졸로 피리미딘
|
|
US7405220B2
(en)
*
|
2004-06-09 |
2008-07-29 |
Hoffmann-La Roche Inc. |
Pyrazolopyrimidines
|
|
US7534767B2
(en)
|
2004-06-15 |
2009-05-19 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase
|
|
EP1912643A2
(en)
*
|
2004-06-23 |
2008-04-23 |
Idenix (Cayman) Limited |
5-aza-7-deazapurine derivatives for treating infections with flaviviridae
|
|
WO2006012078A2
(en)
|
2004-06-24 |
2006-02-02 |
Merck & Co., Inc. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
DE602005015466D1
(de)
*
|
2004-08-23 |
2009-08-27 |
Hoffmann La Roche |
Antivirale 4'-azidonucleoside
|
|
SI3109244T1
(sl)
|
2004-09-14 |
2019-06-28 |
Gilead Pharmasset Llc |
Priprava 2'fluoro-2'-alkil-substituiranih ali drugih neobvezno substituiranih ribofuranozil pirimidinov in purinov in njihovih derivatov
|
|
WO2006093801A1
(en)
*
|
2005-02-25 |
2006-09-08 |
Abbott Laboratories |
Thiadiazine derivatives useful as anti-infective agents
|
|
US7524831B2
(en)
|
2005-03-02 |
2009-04-28 |
Schering Corporation |
Treatments for Flaviviridae virus infection
|
|
US8802840B2
(en)
|
2005-03-08 |
2014-08-12 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
|
JP4516863B2
(ja)
*
|
2005-03-11 |
2010-08-04 |
株式会社ケンウッド |
音声合成装置、音声合成方法及びプログラム
|
|
JP4705164B2
(ja)
|
2005-05-02 |
2011-06-22 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Hcvns3プロテアーゼ阻害剤
|
|
TWI387603B
(zh)
|
2005-07-20 |
2013-03-01 |
Merck Sharp & Dohme |
Hcv ns3蛋白酶抑制劑
|
|
WO2007016441A1
(en)
|
2005-08-01 |
2007-02-08 |
Merck & Co., Inc. |
Macrocyclic peptides as hcv ns3 protease inhibitors
|
|
US7705009B2
(en)
*
|
2005-11-22 |
2010-04-27 |
Hoffman-La Roche Inc. |
4-aminopyrimidine-5-thione derivatives
|
|
NZ568909A
(en)
|
2005-12-09 |
2011-10-28 |
Hoffmann La Roche |
Antiviral 4-fluoro-4-methyl nucleoside prodrugs
|
|
US7763731B2
(en)
|
2005-12-21 |
2010-07-27 |
Abbott Laboratories |
Anti-viral compounds
|
|
US7915411B2
(en)
|
2005-12-21 |
2011-03-29 |
Abbott Laboratories |
Anti-viral compounds
|
|
AU2006330924B2
(en)
*
|
2005-12-21 |
2012-03-15 |
Abbvie Inc. |
Anti-viral compounds
|
|
EP2345652A1
(en)
|
2005-12-21 |
2011-07-20 |
Abbott Laboratories |
Antiviral compounds
|
|
WO2007075876A2
(en)
*
|
2005-12-23 |
2007-07-05 |
Idenix Pharmaceuticals, Inc. |
Process for preparing a synthetic intermediate for preparation of branched nucleosides
|
|
KR101237312B1
(ko)
*
|
2006-02-10 |
2013-03-04 |
삼진제약주식회사 |
피리미딘다이온 유도체를 포함하는 c형 간염의 예방 및치료용 약학 조성물
|
|
US8895531B2
(en)
|
2006-03-23 |
2014-11-25 |
Rfs Pharma Llc |
2′-fluoronucleoside phosphonates as antiviral agents
|
|
WO2010005847A1
(en)
*
|
2008-07-08 |
2010-01-14 |
The Regents Of The University Of California |
Acid-degradable and bioerodible modified polyhydroxylated materials
|
|
US9644039B2
(en)
*
|
2006-03-24 |
2017-05-09 |
The Regents Of The University Of California |
Acid-degradable and bioerodible modified polyhydroxylated materials
|
|
MX2008013119A
(es)
|
2006-04-11 |
2008-10-21 |
Novartis Ag |
Inhibidores de hcv/vih y sus usos.
|
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
GB0612423D0
(en)
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
WO2008011337A1
(en)
*
|
2006-07-19 |
2008-01-24 |
Abbott Laboratories |
Hcv inhibitors
|
|
US20090298708A1
(en)
*
|
2006-08-23 |
2009-12-03 |
Masad Damha J |
2'-deoxy-2'-fluoro-beta-d-arabinonucleoside 5'-triphosphates and their use in enzymatic nucleic acid synthesis
|
|
PT2084175E
(pt)
*
|
2006-10-10 |
2011-04-01 |
Medivir Ab |
Inibidor nucleosídico de vhc
|
|
JP5252459B2
(ja)
|
2006-10-10 |
2013-07-31 |
ギリアド ファーマセット エルエルシー |
リボフラノシルピリミジンヌクレオシドの調製
|
|
JP5345941B2
(ja)
|
2006-10-24 |
2013-11-20 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Hcvns3プロテアーゼ阻害剤
|
|
US8377873B2
(en)
|
2006-10-24 |
2013-02-19 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
CA2667146C
(en)
|
2006-10-24 |
2016-01-19 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
KR101615500B1
(ko)
|
2006-10-27 |
2016-04-27 |
머크 샤프 앤드 돔 코포레이션 |
Hcv ns3 프로테아제 억제제
|
|
US8377874B2
(en)
|
2006-10-27 |
2013-02-19 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
GB0625345D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
GB0625349D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
WO2008133753A2
(en)
*
|
2006-12-20 |
2008-11-06 |
Abbott Laboratories |
Anti-viral compounds
|
|
JP2010513450A
(ja)
|
2006-12-20 |
2010-04-30 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
抗ウイルス性インドール
|
|
US20080261913A1
(en)
|
2006-12-28 |
2008-10-23 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of liver disorders
|
|
WO2008085508A2
(en)
|
2007-01-05 |
2008-07-17 |
Merck & Co., Inc. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
EP2144604B1
(en)
|
2007-02-28 |
2011-09-21 |
Conatus Pharmaceuticals, Inc. |
Methods for the treatment of chronic viral hepatitis C using RO 113-0830
|
|
ZA200906010B
(en)
*
|
2007-03-23 |
2010-08-25 |
Southern Res Inst |
Method for treating and preventing arthritis
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
CN100532388C
(zh)
*
|
2007-07-16 |
2009-08-26 |
郑州大学 |
2’-氟-4’-取代-核苷类似物、其制备方法及应用
|
|
AU2008277440A1
(en)
|
2007-07-17 |
2009-01-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Macrocyclic indole derivatives for the treatment of hepatitis C infections
|
|
JP5433573B2
(ja)
|
2007-07-19 |
2014-03-05 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・エルレ・エルレ |
抗ウイルス剤としての大環状化合物
|
|
WO2009058800A2
(en)
*
|
2007-10-29 |
2009-05-07 |
President And Fellows Of Harvard College |
Synthesis of nucleosides
|
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
AU2009241445A1
(en)
|
2008-04-28 |
2009-11-05 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
US20090274686A1
(en)
*
|
2008-05-02 |
2009-11-05 |
Yat Sun Or |
Nucleoside phosphonate derivatives
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
US20100003217A1
(en)
|
2008-07-02 |
2010-01-07 |
Erika Cretton-Scott |
Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections
|
|
EP2313102A2
(en)
|
2008-07-03 |
2011-04-27 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
PT2310095E
(pt)
|
2008-07-22 |
2012-11-16 |
Angeletti P Ist Richerche Bio |
Compostos de quinoxalina macrocílicos como inibidores da protease ns3 do hcv
|
|
SG172363A1
(en)
|
2008-12-23 |
2011-07-28 |
Pharmasset Inc |
Synthesis of purine nucleosides
|
|
AR074897A1
(es)
|
2008-12-23 |
2011-02-23 |
Pharmasset Inc |
Fosforamidatos de nucleosidos
|
|
CN102753563A
(zh)
|
2008-12-23 |
2012-10-24 |
吉利德制药有限责任公司 |
核苷类似物
|
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
|
JP5690286B2
(ja)
|
2009-03-04 |
2015-03-25 |
イデニク プハルマセウティカルス,インコーポレイテッド |
ホスホチオフェン及びホスホチアゾールhcvポリメラーゼ阻害剤
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
CA2761880A1
(en)
*
|
2009-05-12 |
2010-11-18 |
John A. Secrist, Iii |
2'-fluoro arabino nucleosides and use thereof
|
|
WO2010132163A1
(en)
|
2009-05-13 |
2010-11-18 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic compounds as hepatitis c virus inhibitors
|
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
WO2011014487A1
(en)
|
2009-07-30 |
2011-02-03 |
Merck Sharp & Dohme Corp. |
Hepatitis c virus ns3 protease inhibitors
|
|
WO2011014882A1
(en)
|
2009-07-31 |
2011-02-03 |
Medtronic, Inc. |
CONTINUOUS SUBCUTANEOUS ADMINISTRATION OF INTERFERON-α TO HEPATITIS C INFECTED PATIENTS
|
|
US9284307B2
(en)
|
2009-08-05 |
2016-03-15 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors
|
|
BR112012011221A2
(pt)
|
2009-11-14 |
2016-04-05 |
Hoffmann La Roche |
biomarcadores para prever resposta rápida ao tratamento de hcv
|
|
US8816074B2
(en)
*
|
2009-11-16 |
2014-08-26 |
University of Georgia Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
|
US9700560B2
(en)
|
2009-11-16 |
2017-07-11 |
University Of Georgia Research Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
RU2012127201A
(ru)
|
2009-12-02 |
2014-01-20 |
Ф.Хоффманн-Ля Рош Аг |
Биомаркеры для прогнозирования устойчивого ответа на лечение вируса гепатита с
|
|
AR079528A1
(es)
|
2009-12-18 |
2012-02-01 |
Idenix Pharmaceuticals Inc |
Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
|
|
WO2011123668A2
(en)
|
2010-03-31 |
2011-10-06 |
Pharmasset, Inc. |
Stereoselective synthesis of phosphorus containing actives
|
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
|
EP2552203B1
(en)
|
2010-04-01 |
2017-03-22 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US9284188B2
(en)
|
2010-09-03 |
2016-03-15 |
The Regents Of The University Of California |
Cytosolic delivery of materials with endosome-disrupting colloids
|
|
NZ703416A
(en)
|
2010-09-21 |
2016-06-24 |
Enanta Pharm Inc |
Macrocyclic proline derived hcv serine protease inhibitors
|
|
JP5909495B2
(ja)
|
2010-10-08 |
2016-04-26 |
ノバルティス アーゲー |
スルファミドns3阻害剤のビタミンe製剤
|
|
EP2646453A1
(en)
|
2010-11-30 |
2013-10-09 |
Gilead Pharmasset LLC |
Compounds
|
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
|
US9353100B2
(en)
|
2011-02-10 |
2016-05-31 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
|
|
CA2843324A1
(en)
|
2011-03-31 |
2012-11-15 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
AU2012242978A1
(en)
|
2011-04-13 |
2013-10-24 |
Merck Sharp & Dohme Corp. |
2'-Cyano Substituted Nucleoside Derivatives and methods of use thereof for the treatment of viral diseases
|
|
JP2014515023A
(ja)
|
2011-04-13 |
2014-06-26 |
メルク・シャープ・アンド・ドーム・コーポレーション |
2’−置換ヌクレオシド誘導体およびウイルス疾患の処置のためのその使用方法
|
|
EP2697242B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
EP2731433A4
(en)
|
2011-07-13 |
2014-12-31 |
Merck Sharp & Dohme |
5'-SUBSTITUTED NUCLEOSIDE ANALOGA AND METHOD FOR THEIR USE FOR THE TREATMENT OF VIRUS DISEASES
|
|
US9416154B2
(en)
|
2011-07-13 |
2016-08-16 |
Merck Sharp & Dohme Corp. |
5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
US9403863B2
(en)
|
2011-09-12 |
2016-08-02 |
Idenix Pharmaceuticals Llc |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
|
JP2014526474A
(ja)
|
2011-09-12 |
2014-10-06 |
アイディニックス ファーマシューティカルズ インコーポレイテッド |
ウイルス感染の治療のための化合物および薬学的組成物
|
|
SG10201602044WA
(en)
|
2011-09-16 |
2016-04-28 |
Gilead Pharmassett Llc |
Methods For Treating HCV
|
|
US8507460B2
(en)
|
2011-10-14 |
2013-08-13 |
Idenix Pharmaceuticals, Inc. |
Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2776438A4
(en)
*
|
2011-11-10 |
2015-04-29 |
Inhibitex Inc |
SUBSTITUTED PURIN NUCLEOSIDES, PHOSPHORAMIDATE AND PHOSPHORDIAMIDATE DERIVATIVES FOR THE TREATMENT OF VIRUS INFECTIONS
|
|
EP2780026B1
(en)
|
2011-11-15 |
2019-10-23 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
CN107898790B
(zh)
|
2011-11-30 |
2024-06-21 |
埃默里大学 |
用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
|
|
WO2013106344A1
(en)
|
2012-01-12 |
2013-07-18 |
Ligand Pharmaceuticals, Inc. |
2 '-c-methyl nucleosides containing a cyclic phosphate diester of 1, 3-propanediol (2-oxo-[1, 3, 2]-dioxaphosphorinane) at position 5'
|
|
WO2013133927A1
(en)
|
2012-02-13 |
2013-09-12 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions of 2'-c-methyl-guanosine, 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl n-(phenylmethyl)phosphoramidate]
|
|
BR112014019897A8
(pt)
|
2012-02-14 |
2017-07-11 |
Univ Georgia |
Espiro[2.4]heptanos para tratamento de infecções por flaviviridae
|
|
AU2013266393B2
(en)
|
2012-05-22 |
2017-09-28 |
Idenix Pharmaceuticals Llc |
D-amino acid compounds for liver disease
|
|
EP2852604B1
(en)
|
2012-05-22 |
2017-04-12 |
Idenix Pharmaceuticals LLC |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
|
EP2852605B1
(en)
|
2012-05-22 |
2018-01-31 |
Idenix Pharmaceuticals LLC |
3',5'-cyclic phosphate prodrugs for hcv infection
|
|
WO2013174962A1
(en)
|
2012-05-25 |
2013-11-28 |
Janssen R&D Ireland |
Uracyl spirooxetane nucleosides
|
|
EP2900682A1
(en)
|
2012-09-27 |
2015-08-05 |
IDENIX Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
|
CN104603146B
(zh)
|
2012-09-29 |
2018-01-02 |
诺华股份有限公司 |
环肽类化合物及其作为药物的用途
|
|
EA030189B8
(ru)
|
2012-10-08 |
2018-10-31 |
Иденикс Фармасьютикалз Ллс |
Аналоги 2'-хлоронуклеозидов для инфекции вгс
|
|
EP2909223B1
(en)
|
2012-10-19 |
2017-03-22 |
Idenix Pharmaceuticals LLC |
Dinucleotide compounds for hcv infection
|
|
US10723754B2
(en)
|
2012-10-22 |
2020-07-28 |
Idenix Pharmaceuticals Llc |
2′,4′-bridged nucleosides for HCV infection
|
|
US20140140951A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-Alanine Ester of Rp-Nucleoside Analog
|
|
EP2938624A1
(en)
|
2012-11-14 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
|
WO2014099941A1
(en)
|
2012-12-19 |
2014-06-26 |
Idenix Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
|
CN110684067A
(zh)
|
2012-12-21 |
2020-01-14 |
艾丽奥斯生物制药有限公司 |
取代的核苷和核苷酸
|
|
AU2014202687A1
(en)
|
2013-01-31 |
2014-08-14 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
|
EP2970357B1
(en)
|
2013-03-13 |
2025-01-01 |
Idenix Pharmaceuticals LLC |
Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
|
|
RU2534613C2
(ru)
|
2013-03-22 |
2014-11-27 |
Александр Васильевич Иващенко |
Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения
|
|
EP2981542B1
(en)
|
2013-04-01 |
2021-09-15 |
Idenix Pharmaceuticals LLC |
2',4'-fluoro nucleosides for the treatment of hcv
|
|
WO2014197578A1
(en)
|
2013-06-05 |
2014-12-11 |
Idenix Pharmaceuticals, Inc. |
1',4'-thio nucleosides for the treatment of hcv
|
|
EP3027636B1
(en)
|
2013-08-01 |
2022-01-05 |
Idenix Pharmaceuticals LLC |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
|
SI3038601T1
(sl)
|
2013-08-27 |
2020-07-31 |
Gilead Pharmasset Llc |
Formulacija kombinacije dveh protivirusnih spojin
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
CN105722977A
(zh)
|
2013-10-30 |
2016-06-29 |
绿色生活生物技术有限责任公司 |
用于柑橘绿化枯萎病的发病定量系统和治疗方法
|
|
EP3063165A1
(en)
|
2013-11-01 |
2016-09-07 |
Idenix Pharmaceuticals LLC |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
|
EP3074399A1
(en)
|
2013-11-27 |
2016-10-05 |
Idenix Pharmaceuticals LLC |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
|
EP3083654A1
(en)
|
2013-12-18 |
2016-10-26 |
Idenix Pharmaceuticals LLC |
4'-or nucleosides for the treatment of hcv
|
|
JP2017512183A
(ja)
|
2014-02-13 |
2017-05-18 |
リガンド・ファーマシューティカルズ・インコーポレイテッド |
プロドラッグ化合物およびそれらの使用
|
|
US20170135990A1
(en)
|
2014-03-05 |
2017-05-18 |
Idenix Pharmaceuticals Llc |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
WO2015161137A1
(en)
|
2014-04-16 |
2015-10-22 |
Idenix Pharmaceuticals, Inc. |
3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
|
|
WO2016003812A1
(en)
|
2014-07-02 |
2016-01-07 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and uses therof
|
|
KR102363946B1
(ko)
|
2015-03-06 |
2022-02-17 |
아테아 파마슈티컬즈, 인크. |
HCV 치료를 위한 β-D-2'-데옥시-2'-α-플루오로-2'-β-C-치환된-2-변형된-N6-치환된 퓨린 뉴클레오티드
|
|
CA2997170A1
(en)
*
|
2015-09-02 |
2017-03-09 |
Abbvie Inc. |
Anti-viral tetrahydrofurane derivatives
|
|
US10202412B2
(en)
|
2016-07-08 |
2019-02-12 |
Atea Pharmaceuticals, Inc. |
β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections
|
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
EP4088725A1
(en)
|
2016-09-07 |
2022-11-16 |
ATEA Pharmaceuticals, Inc. |
2'-substituted-n6-substituted purine nucleotides for the treatment of a virus from the picornaviridae family
|
|
EP3554255B1
(en)
|
2016-12-15 |
2023-07-19 |
Société des Produits Nestlé S.A. |
Compositions and methods that modulate cholesterol in a companion animal
|
|
US11758928B2
(en)
|
2016-12-15 |
2023-09-19 |
Société des Produits Nestlé S.A. |
Compositions and methods that modulate phosphorus or enzymes in a companion animal
|
|
CN110248951B
(zh)
|
2017-02-01 |
2022-10-28 |
阿堤亚制药公司 |
用于治疗丙型肝炎病毒的核苷酸半硫酸盐
|
|
ES2892402T3
(es)
|
2017-08-01 |
2022-02-04 |
Gilead Sciences Inc |
Formas cristalinas de ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-il)-4-fluoro-2,5-dihidrofuran-2-il)oxi)metil)(fenoxi)fosforil)-L-alaninato de etilo para tratar infecciones virales
|
|
CN111788196A
(zh)
|
2018-01-09 |
2020-10-16 |
配体药物公司 |
缩醛化合物及其治疗用途
|
|
WO2019200005A1
(en)
|
2018-04-10 |
2019-10-17 |
Atea Pharmaceuticals, Inc. |
Treatment of hcv infected patients with cirrhosis
|
|
JP7496132B2
(ja)
*
|
2018-08-31 |
2024-06-06 |
国立大学法人 鹿児島大学 |
核酸アナログ及び抗b型肝炎ウイルス剤
|
|
WO2020117849A1
(en)
|
2018-12-04 |
2020-06-11 |
Bristol-Myers Squibb Company |
Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
US20240261317A1
(en)
*
|
2021-05-17 |
2024-08-08 |
Rome Therapeutics, Inc. |
Methods of treating medical conditions and inhibiting line1 reverse transcriptaseusing a substituted 4-fluoro-2,5-dihydrofuranyl phosphonic acid or related compound
|
|
CA3174073A1
(en)
|
2021-06-17 |
2022-12-17 |
Atea Pharmaceuticals, Inc. |
Advantageous anti-hcv combination therapy
|