|
US5703058A
(en)
|
1995-01-27 |
1997-12-30 |
Emory University |
Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
|
|
WO1999043691A1
(en)
|
1998-02-25 |
1999-09-02 |
Emory University |
2'-fluoronucleosides
|
|
KR20030005197A
(ko)
|
2000-02-18 |
2003-01-17 |
샤이어 바이오켐 인코포레이티드 |
뉴클레오시드유도체를 이용한 플라비바이러스 감염의 치료또는 예방 방법
|
|
EP1964569A3
(en)
|
2000-04-13 |
2009-07-22 |
Pharmasset, Inc. |
3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of viral infections
|
|
MY164523A
(en)
*
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
EP1736478B1
(en)
*
|
2000-05-26 |
2015-07-22 |
IDENIX Pharmaceuticals, Inc. |
Methods and compositions for treating flaviviruses and pestiviruses
|
|
FR2810319A1
(fr)
*
|
2000-06-15 |
2001-12-21 |
Ppg Sipsy |
Composes alpha-phenylsulfinyl-alpha-halogeno-butyrolactone et halogeno-2-buten-2-olide-4 utiles pour la preparation de composes halogeno-2-oxymethyl-4-furanone (4h)
|
|
US20030008841A1
(en)
*
|
2000-08-30 |
2003-01-09 |
Rene Devos |
Anti-HCV nucleoside derivatives
|
|
WO2002032920A2
(en)
*
|
2000-10-18 |
2002-04-25 |
Pharmasset Limited |
Modified nucleosides for treatment of viral infections and abnormal cellular proliferation
|
|
US7105499B2
(en)
*
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
SK286630B6
(sk)
*
|
2001-01-22 |
2009-02-05 |
Merck & Co., Inc. |
Nukleozidové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
|
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
US6900315B2
(en)
|
2001-02-06 |
2005-05-31 |
Yale University |
2-amino-9H-purin-9-yl compounds and methods for inhibiting/treating HIV infections and AIDS related symptoms
|
|
CA2439836A1
(en)
|
2001-03-01 |
2002-09-12 |
Pharmasset, Inc. |
Method for the synthesis of 2',3'-dideoxy-2',3'-didehydronucleosides
|
|
WO2002069903A2
(en)
*
|
2001-03-06 |
2002-09-12 |
Biocryst Pharmaceuticals, Inc. |
Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
|
GB0112617D0
(en)
*
|
2001-05-23 |
2001-07-18 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
EP1478322A4
(en)
|
2001-06-22 |
2007-08-08 |
Pharmasset Ltd |
Beta 2'-OR 3'-HALONUCLEOSIDE
|
|
EP1435974A4
(en)
|
2001-09-28 |
2006-09-06 |
Idenix Cayman Ltd |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEPATITIS C VIRUS USING 4 'MODIFIED NUCLEOSIDES
|
|
US7049303B2
(en)
*
|
2001-11-07 |
2006-05-23 |
Medical Research Council |
Inhibition of viruses
|
|
AU2002365234B2
(en)
*
|
2001-12-14 |
2009-01-29 |
Pharmasset Inc |
N4-acylcytosine nucleosides for treatment of viral infections
|
|
JP2005522443A
(ja)
*
|
2002-02-14 |
2005-07-28 |
フアーマセツト・リミテツド |
改変フッ素化ヌクレオシド類似体
|
|
TW200500375A
(en)
|
2002-06-28 |
2005-01-01 |
Idenix Cayman Ltd |
Modified 2' and 3'-nucleoside prodrugs for treating flaviviridae
|
|
NZ537662A
(en)
*
|
2002-06-28 |
2007-10-26 |
Idenix Cayman Ltd |
2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
CN1678326A
(zh)
|
2002-06-28 |
2005-10-05 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2'－c－甲基－3'－o－l－缬氨酸酯核糖呋喃基胞苷
|
|
WO2004013300A2
(en)
|
2002-08-01 |
2004-02-12 |
Pharmasset Inc. |
Compounds with the bicyclo[4.2.1]nonane system for the treatment of flaviviridae infections
|
|
US20040067877A1
(en)
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
|
US6884880B2
(en)
*
|
2002-08-21 |
2005-04-26 |
Ash Stevens, Inc. |
Process for the preparation of 9-β-anomeric nucleoside analogs
|
|
US7902203B2
(en)
*
|
2002-11-01 |
2011-03-08 |
Abbott Laboratories, Inc. |
Anti-infective agents
|
|
LT1576138T
(lt)
|
2002-11-15 |
2017-06-26 |
Idenix Pharmaceuticals Llc |
2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija
|
|
AU2003300901A1
(en)
*
|
2002-12-12 |
2004-06-30 |
Idenix (Cayman) Limited |
Process for the production of 2'-branched nucleosides
|
|
NZ540913A
(en)
*
|
2002-12-23 |
2008-02-29 |
Idenix Cayman Ltd |
Process for the production of 3'-nucleoside prodrugs
|
|
WO2004084796A2
(en)
*
|
2003-03-28 |
2004-10-07 |
Pharmasset Ltd. |
Compounds for the treatment of flaviviridae infections
|
|
KR20060015542A
(ko)
*
|
2003-04-28 |
2006-02-17 |
이데닉스 (케이만) 리미티드 |
산업 규모의 뉴클레오시드 합성
|
|
HUE029877T2
(en)
|
2003-05-30 |
2017-04-28 |
Gilead Pharmasset Llc |
Modified fluorinated nucleoside analogues
|
|
WO2005003374A2
(en)
*
|
2003-06-30 |
2005-01-13 |
Idenix (Cayman) Limited |
SYNTHESIS OF β-L-2-DEOXY NUCLEOSIDES
|
|
US20050075309A1
(en)
|
2003-07-25 |
2005-04-07 |
Richard Storer |
Purine nucleoside analogues for treating Flaviviridae including hepatitis C
|
|
WO2005018330A1
(en)
*
|
2003-08-18 |
2005-03-03 |
Pharmasset, Inc. |
Dosing regimen for flaviviridae therapy
|
|
NZ546055A
(en)
|
2003-08-27 |
2010-05-28 |
Biota Scient Management |
Novel tricyclic nucleosides or nucleotides as therapeutic agents
|
|
WO2005026186A1
(de)
*
|
2003-09-12 |
2005-03-24 |
Max-Delbrück-Centrum für Molekulare Medizin |
Β-l-nucleoside und ihre verwendung als pharmazeutische mittel zur behandlung viraler erkrankungen
|
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
|
US7405220B2
(en)
*
|
2004-06-09 |
2008-07-29 |
Hoffmann-La Roche Inc. |
Pyrazolopyrimidines
|
|
KR100839394B1
(ko)
*
|
2004-06-09 |
2008-06-20 |
에프. 호프만-라 로슈 아게 |
피라졸로 피리미딘
|
|
CA2568379A1
(en)
|
2004-06-15 |
2005-12-29 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
|
CA2571675A1
(en)
*
|
2004-06-23 |
2006-01-05 |
Idenix (Cayman) Limited |
5-aza-7-deazapurine derivatives for treating infections with flaviviridae
|
|
CA2571079A1
(en)
|
2004-06-24 |
2006-02-02 |
Merck & Co., Inc. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
CN101023094B
(zh)
*
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
WO2006021341A1
(en)
*
|
2004-08-23 |
2006-03-02 |
F. Hoffmann-La Roche Ag |
Antiviral 4’-azido-nucleosides
|
|
US8492539B2
(en)
*
|
2004-09-14 |
2013-07-23 |
Gilead Pharmasset Llc |
Preparation of 2′-fluoro-2′-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
|
|
WO2006093801A1
(en)
*
|
2005-02-25 |
2006-09-08 |
Abbott Laboratories |
Thiadiazine derivatives useful as anti-infective agents
|
|
US7524831B2
(en)
*
|
2005-03-02 |
2009-04-28 |
Schering Corporation |
Treatments for Flaviviridae virus infection
|
|
CA2600886A1
(en)
|
2005-03-08 |
2006-09-14 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
|
JP4516863B2
(ja)
*
|
2005-03-11 |
2010-08-04 |
株式会社ケンウッド |
音声合成装置、音声合成方法及びプログラム
|
|
AU2006242475B2
(en)
|
2005-05-02 |
2011-07-07 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
TWI387603B
(zh)
|
2005-07-20 |
2013-03-01 |
Merck Sharp & Dohme |
Ｈｃｖ ｎｓ３蛋白酶抑制劑
|
|
BRPI0614205A2
(pt)
|
2005-08-01 |
2016-11-22 |
Merck & Co Inc |
composto, composição farmacêutica, e, uso de composto
|
|
US7705009B2
(en)
*
|
2005-11-22 |
2010-04-27 |
Hoffman-La Roche Inc. |
4-aminopyrimidine-5-thione derivatives
|
|
CA2632626C
(en)
*
|
2005-12-09 |
2011-10-11 |
F. Hoffmann-La Roche Ag |
Ester prodrugs of 2'-fluoro-2'-alkyl-2'-deoxycytidines and their use in the treatment of hcv infection
|
|
EP1979349B1
(en)
*
|
2005-12-21 |
2010-07-28 |
Abbott Laboratories |
Anti-viral compounds
|
|
WO2007081517A2
(en)
|
2005-12-21 |
2007-07-19 |
Abbott Laboratories |
Anti-viral compounds
|
|
US7910595B2
(en)
*
|
2005-12-21 |
2011-03-22 |
Abbott Laboratories |
Anti-viral compounds
|
|
EP2345652A1
(en)
|
2005-12-21 |
2011-07-20 |
Abbott Laboratories |
Antiviral compounds
|
|
ES2422290T3
(es)
*
|
2005-12-23 |
2013-09-10 |
Idenix Pharmaceuticals Inc |
Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados
|
|
KR101237312B1
(ko)
*
|
2006-02-10 |
2013-03-04 |
삼진제약주식회사 |
피리미딘다이온 유도체를 포함하는 ｃ형 간염의 예방 및치료용 약학 조성물
|
|
US8895531B2
(en)
*
|
2006-03-23 |
2014-11-25 |
Rfs Pharma Llc |
2′-fluoronucleoside phosphonates as antiviral agents
|
|
US9644039B2
(en)
|
2006-03-24 |
2017-05-09 |
The Regents Of The University Of California |
Acid-degradable and bioerodible modified polyhydroxylated materials
|
|
WO2010005847A1
(en)
*
|
2008-07-08 |
2010-01-14 |
The Regents Of The University Of California |
Acid-degradable and bioerodible modified polyhydroxylated materials
|
|
EP2007789B1
(en)
|
2006-04-11 |
2015-05-20 |
Novartis AG |
Spirocyclic HCV/HIV inhibitors and their uses
|
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
GB0612423D0
(en)
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
WO2008011337A1
(en)
*
|
2006-07-19 |
2008-01-24 |
Abbott Laboratories |
Hcv inhibitors
|
|
US20090298708A1
(en)
*
|
2006-08-23 |
2009-12-03 |
Masad Damha J |
2'-deoxy-2'-fluoro-beta-d-arabinonucleoside 5'-triphosphates and their use in enzymatic nucleic acid synthesis
|
|
KR101057239B1
(ko)
|
2006-10-10 |
2011-08-16 |
에프. 호프만-라 로슈 아게 |
뉴클레오사이드 리보푸라노실 피리미딘의 제조
|
|
AP2009004812A0
(en)
*
|
2006-10-10 |
2009-04-30 |
Medivir Ab |
HCV nucleoside inhibitor
|
|
CN101583372A
(zh)
|
2006-10-24 |
2009-11-18 |
默克公司 |
Hcv ns3蛋白酶抑制剂
|
|
JP2010507656A
(ja)
|
2006-10-24 |
2010-03-11 |
メルク エンド カムパニー インコーポレーテッド |
Ｈｃｖｎｓ３プロテアーゼ阻害剤
|
|
US8138164B2
(en)
|
2006-10-24 |
2012-03-20 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
WO2008057209A1
(en)
|
2006-10-27 |
2008-05-15 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
AU2007318164B2
(en)
|
2006-10-27 |
2013-02-07 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
GB0625349D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
US8236950B2
(en)
*
|
2006-12-20 |
2012-08-07 |
Abbott Laboratories |
Anti-viral compounds
|
|
CN103224506A
(zh)
|
2006-12-20 |
2013-07-31 |
P.安杰莱蒂分子生物学研究所 |
抗病毒的吲哚
|
|
GB0625345D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
US20080261913A1
(en)
|
2006-12-28 |
2008-10-23 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of liver disorders
|
|
JP2010515680A
(ja)
|
2007-01-05 |
2010-05-13 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Ｒｎａ依存性ｒｎａウイルス感染症の治療用としてのヌクレオシドアリールホスホロアミデート
|
|
JP2010520200A
(ja)
|
2007-02-28 |
2010-06-10 |
クオナトウス ファーマシューティカルズ，インコーポレイテッド |
特定のマトリックスメタロプロテイナーゼ（ｍｍｐ）阻害剤を使用する肝疾患を治療する方法
|
|
KR101582570B1
(ko)
*
|
2007-03-23 |
2016-01-06 |
써던 리서취 인스티튜트 |
관절염 치료 및 예방 방법
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
CN100532388C
(zh)
*
|
2007-07-16 |
2009-08-26 |
郑州大学 |
2’-氟-4’-取代-核苷类似物、其制备方法及应用
|
|
AU2008277440A1
(en)
|
2007-07-17 |
2009-01-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Macrocyclic indole derivatives for the treatment of hepatitis C infections
|
|
AU2008277377B2
(en)
|
2007-07-19 |
2013-08-01 |
Msd Italia S.R.L. |
Macrocyclic compounds as antiviral agents
|
|
WO2009058800A2
(en)
*
|
2007-10-29 |
2009-05-07 |
President And Fellows Of Harvard College |
Synthesis of nucleosides
|
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
AU2009241445A1
(en)
|
2008-04-28 |
2009-11-05 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
US20090274686A1
(en)
*
|
2008-05-02 |
2009-11-05 |
Yat Sun Or |
Nucleoside phosphonate derivatives
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
TW201004632A
(en)
|
2008-07-02 |
2010-02-01 |
Idenix Pharmaceuticals Inc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2010002877A2
(en)
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
PT2540350E
(pt)
|
2008-07-22 |
2014-08-27 |
Merck Sharp & Dohme |
Combinações de um composto de quinoxalina macrocílico o qual é um inibidor da protease ns3 do hcv com outros agentes do hcv
|
|
NZ593649A
(en)
|
2008-12-23 |
2013-11-29 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
PA8855601A1
(es)
|
2008-12-23 |
2010-07-27 |
|
Forformidatos de nucleósidos
|
|
AU2009329872B2
(en)
|
2008-12-23 |
2016-07-07 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
|
JP5690286B2
(ja)
|
2009-03-04 |
2015-03-25 |
イデニク プハルマセウティカルス，インコーポレイテッド |
ホスホチオフェン及びホスホチアゾールｈｃｖポリメラーゼ阻害剤
|
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
BRPI1010809A2
(pt)
*
|
2009-05-12 |
2015-10-13 |
Southern Res Inst |
composto, composição farmacêutica, métodos de tratar câncer em mamífero e usos de compostos e de composição farmacêutica
|
|
EP2429568B1
(en)
|
2009-05-13 |
2016-08-17 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic compounds as hepatitis c virus inhibitors
|
|
TWI583692B
(zh)
*
|
2009-05-20 |
2017-05-21 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
US8828930B2
(en)
|
2009-07-30 |
2014-09-09 |
Merck Sharp & Dohme Corp. |
Hepatitis C virus NS3 protease inhibitors
|
|
EP2459211A1
(en)
|
2009-07-31 |
2012-06-06 |
Medtronic, Inc. |
Continuous subcutaneous administration of interferon- to hepatitis c infected patients
|
|
TW201117812A
(en)
|
2009-08-05 |
2011-06-01 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
CA2780044A1
(en)
|
2009-11-14 |
2011-05-19 |
F. Hoffmann-La Roche Ag |
Biomarkers for predicting rapid response to hcv treatment
|
|
US8816074B2
(en)
*
|
2009-11-16 |
2014-08-26 |
University of Georgia Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
|
US9700560B2
(en)
|
2009-11-16 |
2017-07-11 |
University Of Georgia Research Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
WO2011067195A1
(en)
|
2009-12-02 |
2011-06-09 |
F. Hoffmann-La Roche Ag |
Biomarkers for predicting sustained response to hcv treatment
|
|
MX2012006877A
(es)
|
2009-12-18 |
2012-08-31 |
Idenix Pharmaceuticals Inc |
Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado.
|
|
US8563530B2
(en)
|
2010-03-31 |
2013-10-22 |
Gilead Pharmassel LLC |
Purine nucleoside phosphoramidate
|
|
SG184324A1
(en)
|
2010-03-31 |
2012-11-29 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
EP2552203B1
(en)
|
2010-04-01 |
2017-03-22 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US9284188B2
(en)
|
2010-09-03 |
2016-03-15 |
The Regents Of The University Of California |
Cytosolic delivery of materials with endosome-disrupting colloids
|
|
JP5857053B2
(ja)
|
2010-09-21 |
2016-02-10 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
大環式プロリン由来ｈｃｖセリンプロテアーゼ阻害剤
|
|
JP5909495B2
(ja)
|
2010-10-08 |
2016-04-26 |
ノバルティス アーゲー |
スルファミドｎｓ３阻害剤のビタミンｅ製剤
|
|
CA2818853A1
(en)
|
2010-11-30 |
2012-06-07 |
Gilead Pharmasset Llc |
2'-spirocyclo-nucleosides for use in therapy of hcv or dengue virus
|
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
|
US9353100B2
(en)
|
2011-02-10 |
2016-05-31 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
|
|
US9243025B2
(en)
|
2011-03-31 |
2016-01-26 |
Idenix Pharmaceuticals, Llc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
BR112013026345A2
(pt)
|
2011-04-13 |
2019-04-24 |
Merck Sharp & Dohe Corp. |
composto, composição farmacêutica, uso de um composto, e, método para tratar um paciente infectado com hcv
|
|
EP2697242B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2012142093A2
(en)
|
2011-04-13 |
2012-10-18 |
Merck Sharp & Dohme Corp. |
2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013009735A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
US9408863B2
(en)
|
2011-07-13 |
2016-08-09 |
Merck Sharp & Dohme Corp. |
5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
|
|
AR088441A1
(es)
|
2011-09-12 |
2014-06-11 |
Idenix Pharmaceuticals Inc |
Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
CA2847892A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2709613B2
(en)
|
2011-09-16 |
2020-08-12 |
Gilead Pharmasset LLC |
Methods for treating hcv
|
|
US8507460B2
(en)
|
2011-10-14 |
2013-08-13 |
Idenix Pharmaceuticals, Inc. |
Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2776438A4
(en)
*
|
2011-11-10 |
2015-04-29 |
Inhibitex Inc |
SUBSTITUTED PURIN NUCLEOSIDES, PHOSPHORAMIDATE AND PHOSPHORDIAMIDATE DERIVATIVES FOR THE TREATMENT OF VIRUS INFECTIONS
|
|
US9328138B2
(en)
|
2011-11-15 |
2016-05-03 |
Msd Italia S.R.L. |
HCV NS3 protease inhibitors
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
ES3018133T3
(en)
|
2011-11-30 |
2025-05-14 |
Univ Emory |
Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
|
|
WO2013106344A1
(en)
|
2012-01-12 |
2013-07-18 |
Ligand Pharmaceuticals, Inc. |
2 '-c-methyl nucleosides containing a cyclic phosphate diester of 1, 3-propanediol (2-oxo-[1, 3, 2]-dioxaphosphorinane) at position 5'
|
|
US20130217644A1
(en)
|
2012-02-13 |
2013-08-22 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical Compositions of 2'-C-Methyl-Guanosine, 5'-[2[(3-Hydroxy-2,2-Dimethyl-1-Oxopropyl)Thio]Ethyl N-(Phenylmethyl)Phosphoramidate]
|
|
US8673926B2
(en)
|
2012-02-14 |
2014-03-18 |
University Of Georgia Research Foundation, Inc. |
Spiro[2.4]heptanes for treatment of flaviviridae infections
|
|
US9296778B2
(en)
|
2012-05-22 |
2016-03-29 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphate prodrugs for HCV infection
|
|
JP6165848B2
(ja)
|
2012-05-22 |
2017-07-19 |
イデニク ファーマシューティカルズ エルエルシー |
肝疾患のためのｄ−アミノ酸化合物
|
|
WO2013177188A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
|
MX2014014323A
(es)
|
2012-05-25 |
2015-02-12 |
Janssen R & D Ireland |
Nucleosidos de espirooxetano de uracilo.
|
|
WO2014052638A1
(en)
|
2012-09-27 |
2014-04-03 |
Idenix Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
|
EP2900684A2
(en)
|
2012-09-29 |
2015-08-05 |
Novartis AG |
Cyclic peptides and use as medicines
|
|
EP2906579B1
(en)
|
2012-10-08 |
2018-04-18 |
Idenix Pharmaceuticals LLC. |
2'-chloro nucleoside analogs for hcv infection
|
|
EP2909223B1
(en)
|
2012-10-19 |
2017-03-22 |
Idenix Pharmaceuticals LLC |
Dinucleotide compounds for hcv infection
|
|
US10723754B2
(en)
|
2012-10-22 |
2020-07-28 |
Idenix Pharmaceuticals Llc |
2′,4′-bridged nucleosides for HCV infection
|
|
US20140140951A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-Alanine Ester of Rp-Nucleoside Analog
|
|
EP2938624A1
(en)
|
2012-11-14 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
|
EP2935304A1
(en)
|
2012-12-19 |
2015-10-28 |
IDENIX Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
|
BR112015014457A2
(pt)
|
2012-12-21 |
2017-11-21 |
Alios Biopharma Inc |
composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica e respectivos usos e processos para melhorar ou tratar infecção de hcv, para inibir a atividade da ns5b polimerase do vírus da hepatite c e a replicação de vírus da hepatite c
|
|
EP2950786B1
(en)
|
2013-01-31 |
2019-11-27 |
Gilead Pharmasset LLC |
Combination formulation of two antiviral compounds
|
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
|
WO2014137930A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
Thiophosphate nucleosides for the treatment of hcv
|
|
WO2014160484A1
(en)
|
2013-03-13 |
2014-10-02 |
Idenix Pharmaceuticals, Inc. |
Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
|
|
RU2534613C2
(ru)
|
2013-03-22 |
2014-11-27 |
Александр Васильевич Иващенко |
Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения
|
|
EP2981542B1
(en)
|
2013-04-01 |
2021-09-15 |
Idenix Pharmaceuticals LLC |
2',4'-fluoro nucleosides for the treatment of hcv
|
|
US10005779B2
(en)
|
2013-06-05 |
2018-06-26 |
Idenix Pharmaceuticals Llc |
1′,4′-thio nucleosides for the treatment of HCV
|
|
WO2015017713A1
(en)
|
2013-08-01 |
2015-02-05 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
|
PT3038601T
(pt)
|
2013-08-27 |
2020-06-30 |
Gilead Pharmasset Llc |
Formulação combinada de dois compostos antivirais
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
CN105722977A
(zh)
|
2013-10-30 |
2016-06-29 |
绿色生活生物技术有限责任公司 |
用于柑橘绿化枯萎病的发病定量系统和治疗方法
|
|
US20160271162A1
(en)
|
2013-11-01 |
2016-09-22 |
Idenix Pharmacueticals, Llc |
D-alanine phosphoramide pronucleotides of 2'-methyl 2'-fluro guanosine nucleoside compounds for the treatment of hcv
|
|
EP3074399A1
(en)
|
2013-11-27 |
2016-10-05 |
Idenix Pharmaceuticals LLC |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
|
US10683321B2
(en)
|
2013-12-18 |
2020-06-16 |
Idenix Pharmaceuticals Llc |
4′-or nucleosides for the treatment of HCV
|
|
AU2015217221A1
(en)
|
2014-02-13 |
2016-08-11 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and their uses
|
|
WO2015134561A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
US10202411B2
(en)
|
2014-04-16 |
2019-02-12 |
Idenix Pharmaceuticals Llc |
3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV
|
|
CN106687118A
(zh)
|
2014-07-02 |
2017-05-17 |
配体药物公司 |
前药化合物及其用途
|
|
CA3182565A1
(en)
|
2015-03-06 |
2016-09-15 |
Atea Pharmaceuticals, Inc. |
.beta.-d-2'-deoxy-2'-.alpha.-fluoro-2'-.beta.-c-substituted-2-modified-n6-substituted purine nucleotides for hcv treatment
|
|
JP6743135B2
(ja)
|
2015-09-02 |
2020-08-19 |
アッヴィ・インコーポレイテッド |
抗ウィルス性テトラヒドロフラン誘導体
|
|
US10202412B2
(en)
|
2016-07-08 |
2019-02-12 |
Atea Pharmaceuticals, Inc. |
β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections
|
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
WO2018048937A1
(en)
|
2016-09-07 |
2018-03-15 |
Atea Pharmaceuticals, Inc. |
2'-substituted-n6-substituted purine nucleotides for rna virus treatment
|
|
US11234454B2
(en)
|
2016-12-15 |
2022-02-01 |
Société des Produits Nestlé S.A. |
Compositions and methods that modulate cholesterol in a companion animal
|
|
US11758928B2
(en)
|
2016-12-15 |
2023-09-19 |
Société des Produits Nestlé S.A. |
Compositions and methods that modulate phosphorus or enzymes in a companion animal
|
|
IL288737B
(en)
|
2017-02-01 |
2022-09-01 |
Atea Pharmaceuticals Inc |
Hemisulfate nucleotide salt for treatment of hepatitis c virus
|
|
SI3661937T1
(sl)
|
2017-08-01 |
2021-11-30 |
Gilead Sciences, Inc. |
Kristalinične oblike etil((S)-((((2R,5R)-5-(6-amino-9H-purin-9-IL)-4- fluoro-2,5-dihidrofuran-2-IL)oksi)metil)(fenoksi)fosforil)-L-alaninata (GS-9131) za zdravljenje virusnih okužb
|
|
CA3087932A1
(en)
|
2018-01-09 |
2019-07-18 |
Ligand Pharmaceuticals, Inc. |
Acetal compounds and therapeutic uses thereof
|
|
EP3773753A4
(en)
|
2018-04-10 |
2021-12-22 |
ATEA Pharmaceuticals, Inc. |
TREATMENT OF PATIENTS INFECTED WITH THE HEPATITIS C VIRUS WITH CIRRHOSIS
|
|
JP7496132B2
(ja)
*
|
2018-08-31 |
2024-06-06 |
国立大学法人 鹿児島大学 |
核酸アナログ及び抗ｂ型肝炎ウイルス剤
|
|
KR102835299B1
(ko)
|
2018-12-04 |
2025-07-18 |
브리스톨-마이어스 스큅 컴퍼니 |
다중 동위원소체 반응 모니터링에 의한 샘플내 보정 곡선을 사용한 분석 방법
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
US20240261317A1
(en)
*
|
2021-05-17 |
2024-08-08 |
Rome Therapeutics, Inc. |
Methods of treating medical conditions and inhibiting line1 reverse transcriptaseusing a substituted 4-fluoro-2,5-dihydrofuranyl phosphonic acid or related compound
|
|
IL308921A
(en)
|
2021-06-17 |
2024-01-01 |
Atea Pharmaceuticals Inc |
Combination anti-HCV therapy is beneficial
|