JP2008534511A5 - - Google Patents
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- Publication number
- JP2008534511A5 JP2008534511A5 JP2008503223A JP2008503223A JP2008534511A5 JP 2008534511 A5 JP2008534511 A5 JP 2008534511A5 JP 2008503223 A JP2008503223 A JP 2008503223A JP 2008503223 A JP2008503223 A JP 2008503223A JP 2008534511 A5 JP2008534511 A5 JP 2008534511A5
- Authority
- JP
- Japan
- Prior art keywords
- oxo
- adamantyl
- substituted
- acetamide
- unsubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66490305P | 2005-03-24 | 2005-03-24 | |
| US70918605P | 2005-08-18 | 2005-08-18 | |
| US71007705P | 2005-08-22 | 2005-08-22 | |
| US71277805P | 2005-08-31 | 2005-08-31 | |
| US72139005P | 2005-09-28 | 2005-09-28 | |
| US75319405P | 2005-12-22 | 2005-12-22 | |
| PCT/US2006/010774 WO2006102588A1 (en) | 2005-03-24 | 2006-03-24 | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008534511A JP2008534511A (ja) | 2008-08-28 |
| JP2008534511A5 true JP2008534511A5 (https=) | 2009-04-16 |
Family
ID=37024169
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503245A Withdrawn JP2008537741A (ja) | 2005-03-24 | 2006-03-24 | Ｐ２ｘ７調節因子としてのビシクロヘテロアリール化合物およびそれらの使用 |
| JP2008503223A Withdrawn JP2008534511A (ja) | 2005-03-24 | 2006-03-24 | Ｐ２ｘ７調節因子としてのビシクロヘテロアリール化合物およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503245A Withdrawn JP2008537741A (ja) | 2005-03-24 | 2006-03-24 | Ｐ２ｘ７調節因子としてのビシクロヘテロアリール化合物およびそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US7402596B2 (https=) |
| EP (2) | EP1865774A4 (https=) |
| JP (2) | JP2008537741A (https=) |
| CA (2) | CA2602717A1 (https=) |
| MX (2) | MX2007011854A (https=) |
| WO (2) | WO2006102610A2 (https=) |
Families Citing this family (92)
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| HRP20211752T1 (hr) | 2010-04-07 | 2022-02-18 | Vertex Pharmaceuticals Incorporated | Farmaceutski pripravci 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojeve kiseline i njihova primjena |
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| CN103687860B (zh) | 2011-07-22 | 2016-06-08 | 埃科特莱茵药品有限公司 | 作为p2x7受体拮抗剂的杂环酰胺衍生物 |
| TWI561521B (en) * | 2011-10-14 | 2016-12-11 | Abbvie Inc | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
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| KR102232744B1 (ko) | 2012-12-18 | 2021-03-26 | 이도르시아 파마슈티컬스 리미티드 | Ｐ２ｘ７ 수용체 길항제로서의 인돌 카르복사미드 유도체 |
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| KR100751604B1 (ko) | 2003-03-03 | 2007-08-22 | 에프. 호프만-라 로슈 아게 | 5-ｈｔ6 조절자로서 사용되는 2,5- 및 2,6-치환된테트라하이드로아이소퀴놀린 |
| US7223766B2 (en) | 2003-03-28 | 2007-05-29 | Scios, Inc. | Bi-cyclic pyrimidine inhibitors of TGFβ |
| GB0312609D0 (en) * | 2003-06-02 | 2003-07-09 | Astrazeneca Ab | Novel compounds |
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| CN1566099A (zh) * | 2003-06-13 | 2005-01-19 | 中国科学院上海药物研究所 | 异喹啉－1,3,4－三酮类化合物、制备方法及其用途 |
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| CN1894222A (zh) | 2003-08-05 | 2007-01-10 | 沃泰克斯药物股份有限公司 | 作为电压门控离子通道抑制剂的稠合嘧啶化合物 |
| PT1670458E (pt) | 2003-10-08 | 2007-03-30 | Schering Ag | Derivados de tetra-hidronaftaleno, processo para a sua preparação e utilização como inibidor de inflamação |
| JP2007008816A (ja) | 2003-10-15 | 2007-01-18 | Ube Ind Ltd | 新規イソキノリン誘導体 |
| US7419978B2 (en) | 2003-10-22 | 2008-09-02 | Bristol-Myers Squibb Company | Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors |
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| SE0400284D0 (sv) | 2004-02-10 | 2004-02-10 | Astrazeneca Ab | Novel compounds |
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| US20050267202A1 (en) * | 2004-05-19 | 2005-12-01 | Konrad Krolikiewicz | Chromanol derivatives, a process for their production and their use as anti-inflammatory agents |
| GB0420722D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| KR20070058602A (ko) | 2004-09-30 | 2007-06-08 | 티보텍 파마슈티칼즈 리미티드 | Ｈｃｖ 저해 바이-사이클릭 피리미딘 |
| DE102004055633A1 (de) | 2004-11-12 | 2006-05-18 | Schering Ag | 5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| WO2006057270A1 (ja) | 2004-11-26 | 2006-06-01 | Asahi Kasei Pharma Corporation | 含窒素３環化合物 |
| US20060128710A1 (en) | 2004-12-09 | 2006-06-15 | Chih-Hung Lee | Antagonists to the vanilloid receptor subtype 1 (VR1) and uses thereof |
| DE102004063227A1 (de) | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
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| CA2645551C (en) * | 2006-03-16 | 2016-06-28 | Renovis, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
-
2006
- 2006-03-17 US US11/384,199 patent/US7402596B2/en not_active Expired - Fee Related
- 2006-03-17 US US11/384,045 patent/US7297700B2/en not_active Expired - Fee Related
- 2006-03-24 JP JP2008503245A patent/JP2008537741A/ja not_active Withdrawn
- 2006-03-24 WO PCT/US2006/010880 patent/WO2006102610A2/en not_active Ceased
- 2006-03-24 MX MX2007011854A patent/MX2007011854A/es active IP Right Grant
- 2006-03-24 EP EP06739520A patent/EP1865774A4/en not_active Withdrawn
- 2006-03-24 EP EP06739589A patent/EP1860942A4/en not_active Withdrawn
- 2006-03-24 JP JP2008503223A patent/JP2008534511A/ja not_active Withdrawn
- 2006-03-24 MX MX2007011855A patent/MX2007011855A/es active IP Right Grant
- 2006-03-24 WO PCT/US2006/010774 patent/WO2006102588A1/en not_active Ceased
- 2006-03-24 CA CA002602717A patent/CA2602717A1/en not_active Abandoned
- 2006-03-24 CA CA002602718A patent/CA2602718A1/en not_active Abandoned
-
2007
- 2007-07-03 US US11/773,106 patent/US20080039478A1/en not_active Abandoned
-
2008
- 2008-07-16 US US12/218,620 patent/US20090170838A1/en not_active Abandoned
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