JP2008528210A - 薬物送出の装置、システムおよび方法 - Google Patents
薬物送出の装置、システムおよび方法 Download PDFInfo
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- JP2008528210A JP2008528210A JP2007553358A JP2007553358A JP2008528210A JP 2008528210 A JP2008528210 A JP 2008528210A JP 2007553358 A JP2007553358 A JP 2007553358A JP 2007553358 A JP2007553358 A JP 2007553358A JP 2008528210 A JP2008528210 A JP 2008528210A
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Abstract
【解決手段】特定の例示的実施形態は自動注入器を備えることができ、これは注入可能な薬物を貯蔵および/または含むように構成されたバイアルを備えることができ、バイアルはバイアル縦軸を画定し、さらにバイアルを有するハウジングを備えることができる。様々な実施形態で、注入可能な薬物は、実質的にすぐ注入できる状態の薬、薬剤、薬品、調合薬、処方薬、作用物質、解毒薬、抗毒素、ホルモン、類似物、血管拡張剤、麻酔薬および/または栄養補助剤でよい。
【選択図】図1
Description
[1] 本出願は以下の係属中の米国仮特許出願に対する優先権を主張し、参照によりその全体を組み込む。
[35] 本明細書で実質的に以下の用語を使用する場合、付随する定義が適用される。
[125] トリガ可能な−起動されることができる。
[165] この例示的実施形態は、薬物を投与するためにばねおよび/またはガス駆動のシステムを使用する、および/または針保護システムを備える、自動注入器の実現方法について述べる。
[167] 図16は、使用者を偶発的起動から保護するために使用される安全タブを示す。図16は、溝が追加された安全タブの延長部分も示す。これは、より大きい把持表面および/またはタブをさらに触知できる感触を生成することによって、使用者が安全タブを外す際に補助することができる。
[171] 自動注入器の特定の例示的実施形態は、薬物を患者に注入するために、ばねまたは複数のばねを使用することができる。このシステムの新規性は、起動ばねおよびバイアルシステム(プランジャ、バイアル、リザーバおよび針/カニューレを備える)の方位にある。起動ばねは、バイアルシステムに平行に配置することができるので、デバイスは市場にある既存のデバイス(直線の性質である)より小型化することができ、潜在的にほぼクレジットカードのサイズである形状係数を有する。
[174] この例示的実施形態は、薬物を患者に注入する起動機構としてプーリシステムを使用することができ、針保護システムも備えることができる。
[177] この例示的実施形態は、気体および/またはばねで起動することができ、使用者が針を使用せずに薬物を患者に注入できるようにする針なし注入器を備えることができる。複数のバイアルを使用することが、新規の構成要素と見なされ、これによってデバイスは、例えばクレジットカードとほぼ同様の長さおよび幅を有するなど、コンパクトな性質にすることができる。
[180] この例示的実施形態は、複数のバイアルを組み込んで、複数の薬物を1回で、または複数回で注入することができるコンパクトな自動注入器を備えることができる。複数のバイアルを使用することは、新規の構成要素と見なされ、クレジットカードの長さおよび幅を有するなど、コンパクトな性質であるデバイスを生成するという利点を有することもできる。
[183] この例示的実施形態は、液体または粉末の形態の2つ以上の薬物を混合して、1つの注入可能な薬物を生成する能力を有することができるコンパクトな自動注入器を備えることができる。このデバイスの新規の構成要素は、複数のバイアルを使用して薬物を送出することであると見なすことができる。デバイスは、針保護システムも備えることができる。
[186] 特定の例示的実施形態は、自動注入器ハウジングの針が配置されているのと同じ端部で使用者が何らかのキャップ、バー、ロックを外すことができるようにする安全システムを備えることができる。これによって、デバイスをすぐ起動できるようにしながら、同時に針をまだ保護することができる。大部分のペン様注入器のような多くの自動注入器は、針が配置されているのとは反対の端部に起動安全機構を有する。緊急の状況では、使用者はこの安全キャップを、針を保護するものと誤ることがあり、実際にはそうではない。この理由から、使用者の親指または他の指にデジタル注入されたという事例が多く文書化されている。安全機構が針と同じ端部にあると、この危険を解消することができる。
[187] 自動注入器および薬剤送出システムの使用は、医療産業では一般的なことである。自動注入器は、長期的治療から重体患者の注射液まで、ある範囲の薬物を患者に送出することができる。より多くの治療が開発されるにつれ、これらの治療を施す手段の必要性が益々増大している。現在市場にある特定の自動注入器には、使用者がデバイスの機能および/または動作を理解できるようにする特性がないことがある。したがって、自動注入器の適切な操作方法および/またはデバイスを適正に使用しない場合に生じ得る使用者関連の危険の緩和方法に関して、使用者を効果的に訓練および/または案内するために、可聴、触覚および/または視覚的フィードバックを使用者に提供できる自動注入器が必要であると考えられる。
Claims (50)
- 粉末と混合して注入可能な薬物を形成することができる液体から分離して乾性物質を貯蔵するように構成され、バイアル縦軸を画定するバイアルと、
前記乾性物質を前記液体と接触させるように構成された混合アクチュエータと、
前記バイアル内で動くように構成されると共に、前記注入可能な薬物を前記バイアルから単一の針を通って移送するように構成され、前記混合アクチュエータとは別個のピストンと、
前記注入可能な薬物に駆動力を供給するように構成され、前記バイアル縦軸と非同軸に配置された力発生体縦軸を画定する力発生体と、
を備える自動注入器。 - さらに、前記乾性物質と前記液体との混合に抵抗するように構成された脆弱体を備える、請求項1に記載の自動注入器。
- さらに、前記バイアルを備えるハウジングを備え、
前記ハウジングは、クレジットカードに近い長さおよび幅、並びに1インチ未満の厚さを画定する、請求項1に記載の自動注入器。 - 前記混合アクチュエータが前記ピストンに結合される、請求項1に記載の自動注入器。
- 前記混合アクチュエータが前記バイアルに結合される、請求項1に記載の自動注入器。
- さらに、前記ピストンに起動圧力を提供するように構成された圧縮ガス容器を備える、請求項1に記載の自動注入器。
- さらに、前記ピストンに流体結合された圧縮ガス容器の内容物の起動部分を放出するように構成されたアクチュエータを備える、請求項1に記載の自動注入器。
- 前記バイアルが、圧縮ガス容器の内容物の起動部分と流体結合可能である、請求項1に記載の自動注入器。
- さらに、前記注入可能な薬物の少なくとも一部を前記バイアルから前記単一の針へと搬送するように構成されたチャネルを備える、請求項1に記載の自動注入器。
- さらに、前記単一の針を備える、請求項1に記載の自動注入器。
- さらに、前記単一の針を保護するように構成された外装を備える、請求項1に記載の自動注入器。
- さらに、前記注入可能な薬物の注入後に、前記単一の針を隠すように構成された外装を備える、請求項1に記載の自動注入器。
- さらに、前記注入可能な薬物の注入後に、前記単一の針を保護するように構成されたシールドを備える、請求項1に記載の自動注入器。
- さらに、前記自動注入器の偶発的起動を防止するように構成された安全タブを備える、請求項1に記載の自動注入器。
- さらに、前記バイアルおよび前記ピストンを含むように構成されたハウジングを備える、請求項1に記載の自動注入器。
- さらに、前記バイアルおよび前記ピストンを含むように構成されたハウジングを備え、
前記ハウジングが、クレジットカードに近い長さおよび幅、並びに1インチ未満の厚さを画定する、請求項1に記載の自動注入器。 - 前記バイアルが複数のバイアルの1つである、請求項1に記載の自動注入器。
- 前記バイアルが複数のバイアルの1つであり、前記複数のバイアルがそれぞれバイアル縦軸を画定し、前記複数のバイアルのバイアル縦軸が平行かつ非同軸である、請求項1に記載の自動注入器。
- 前記バイアルが複数のバイアルの1つであり、前記複数のバイアルがそれぞれバイアル縦軸を画定し、前記複数のバイアルのバイアル縦軸が、前記力発生体縦軸と非同軸に配置される、請求項1に記載の自動注入器。
- 前記ピストンが複数のピストンの1つである、請求項1に記載の自動注入器。
- 注入可能な薬物を貯蔵するように構成され、バイアル縦軸を画定するバイアルと、
前記注入可能な薬物に駆動力を供給するように構成され、前記バイアル縦軸と非同軸に配置された力発生体縦軸を画定する力発生体と、
前記バイアルを備えるハウジングと、
前記ハウジングに結合され、当該自動注入器の使用者に使用指示を表すように構成された出力デバイスと、を備え、前記使用指示が、マイクロプロセッサによって自動的にトリガ可能な使用指示のグループの1つであり、前記グループが、前記注入可能な薬物の量に関係なく、前記グループが、
自動注入器の交換と、
薬物の混合と、
注入の遅延と、
安全ガードの取り外しと、
自動注入器の配置と、
自動注入器の方位と、
アクチュエータの位置と、
注入危険の回避と、
注入の継続時間と、
注入状態と、
注入エラーと、
自動注入器の取り外しと、
自動注入器の再使用と、
自動注入器のリサイクルと、
自動注入器の配置と、
のうち少なくとも2つに関する、
自動注入器。 - 前記ハウジングが、クレジットカードに近い長さおよび幅、並びに1インチ未満の厚さを画定する、請求項21に記載の自動注入器。
- 前記使用指示が、感知された変数の値に応答してトリガされる、請求項21に記載の自動注入器。
- 前記使用指示が、使用者の入力に応答してトリガされる、請求項21に記載の自動注入器。
- 前記使用指示が、危険な状態の判断に対応してトリガされる、請求項21に記載の自動注入器。
- 前記使用指示が視覚的に表される、請求項21に記載の自動注入器。
- 前記使用指示が聴覚的に表される、請求項21に記載の自動注入器。
- 前記使用指示が触覚的に表される、請求項21に記載の自動注入器。
- 前記ハウジングが前記出力デバイスを備える、請求項21に記載の自動注入器。
- 前記出力デバイスがスピーカを備える、請求項21に記載の自動注入器。
- 前記出力デバイスがディスプレイを備える、請求項21に記載の自動注入器。
- 前記出力デバイスが発光ダイオードを備える、請求項21に記載の自動注入器。
- 前記出力デバイスが振動器を備える、請求項21に記載の自動注入器。
- 前記出力デバイスが加熱器を備える、請求項21に記載の自動注入器。
- さらに前記マイクロプロセッサを備え、前記マイクロプロセッサが前記ハウジングに結合される、請求項21に記載の自動注入器。
- さらに、前記マイクロプロセッサに結合されたセンサを備える、請求項21に記載の自動注入器。
- さらに、前記マイクロプロセッサに結合されたスイッチを備える、請求項21に記載の自動注入器。
- さらに、前記マイクロプロセッサに結合された電池を備える、請求項21に記載の自動注入器。
- さらに、前記バイアル内で動くような構成であるピストンを備える、請求項21に記載の自動注入器。
- さらに、前記ガス容器を備える、請求項21に記載の自動注入器。
- さらに、薬物の少なくとも一部を前記バイアルから針へと搬送するような構成であるチャネルを備える、請求項21に記載の自動注入器。
- 前記注入可能な薬物が液体である、請求項21に記載の自動注入器。
- 前記注入可能な薬物が液体と固体の混合物である、請求項21に記載の自動注入器。
- さらに、前記バイアルに流体結合された針を後退させるような構成であるばねを備える、請求項21に記載の自動注入器。
- さらに、前記自動注入器の偶発的起動を防止するような構成である着脱式の起動ロックを備える、請求項21に記載の自動注入器。
- 前記バイアルが複数のバイアルの1つである、請求項21に記載の自動注入器。
- 前記バイアルが複数のバイアルの1つであり、前記複数のバイアルがそれぞれバイアル縦軸を画定し、前記複数のバイアルのバイアル縦軸が平行かつ非同軸である、請求項21に記載の自動注入器。
- 前記バイアルが複数のバイアルの1つであり、前記複数のバイアルがそれぞれバイアル縦軸を画定し、前記複数のバイアルのバイアル縦軸が、前記力発生体縦軸と非同軸に配置される、請求項21に記載の自動注入器。
- 前記バイアルが複数のバイアルの1つであり、
当該自動注入器は、さらに複数のピストンを備え、
前記複数のピストンがそれぞれ、前記複数のバイアルのうち対応するバイアル内で動くような構成である、請求項21に記載の自動注入器。 - 活動の命令を含むコンピュータが読取可能な媒体であって、
自動注入器の出力デバイスを介して、前記自動注入器の使用者に使用指示を与えることを含み、前記使用指示が、マイクロプロセッサによって自動的にトリガ可能な使用指示のグループの1つであり、前記グループが注入可能な薬物の量に関係なく、前記グループが、
自動注入器の交換と、
薬物の混合と、
注入の遅延と、
安全ガードの取り外しと、
自動注入器の配置と、
自動注入器の方位と、
アクチュエータの位置と、
注入危険の回避と、
注入の継続時間と、
注入状態と、
注入エラーと、
自動注入器の取り外しと、
自動注入器の再使用と、
自動注入器のリサイクルと、
自動注入器の配置と、
のうち少なくとも2つに関連し、
前記自動注入器が、
注入可能な薬物を貯蔵するように構成され、バイアル縦軸を画定するバイアルと、
前記注入可能な薬物に駆動力を供給するように構成され、前記バイアル縦軸と非同軸に配置された力発生体縦軸を画定する力発生体と、
前記バイアルを備えるハウジングと、を備え、前記出力デバイスが前記ハウジングに結合される、
コンピュータが読取可能な媒体。
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US60/731,886 | 2005-10-31 | ||
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