US20030225344A1 - Apparatus and method to access the bone marrow for oncology and stem cell applications - Google Patents

Apparatus and method to access the bone marrow for oncology and stem cell applications Download PDF

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Publication number
US20030225344A1
US20030225344A1 US10/448,650 US44865003A US2003225344A1 US 20030225344 A1 US20030225344 A1 US 20030225344A1 US 44865003 A US44865003 A US 44865003A US 2003225344 A1 US2003225344 A1 US 2003225344A1
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United States
Prior art keywords
drive shaft
hollow drive
bone marrow
operable
bone
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US10/448,650
Inventor
Larry Miller
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Teleflex Life Sciences Ltd
Vidacare LLC
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Vidacare LLC
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Priority to US10/448,650 priority Critical patent/US20030225344A1/en
Application filed by Vidacare LLC filed Critical Vidacare LLC
Assigned to VIDACARE CORPORATION reassignment VIDACARE CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MILLER, LARRY J.
Publication of US20030225344A1 publication Critical patent/US20030225344A1/en
Priority to US11/389,732 priority patent/US20060167378A1/en
Priority to US11/389,733 priority patent/US20060167379A1/en
Priority to US11/380,340 priority patent/US9072543B2/en
Priority to US11/427,501 priority patent/US7951089B2/en
Priority to US11/781,597 priority patent/US20080015468A1/en
Priority to US11/781,568 priority patent/US20080015467A1/en
Priority to US11/853,685 priority patent/US7850620B2/en
Priority to US11/853,691 priority patent/US9545243B2/en
Priority to US12/259,745 priority patent/US9078637B2/en
Priority to US12/427,310 priority patent/US8690791B2/en
Priority to US12/701,268 priority patent/US20100137740A1/en
Priority to US12/963,255 priority patent/US9717564B2/en
Priority to US14/791,654 priority patent/US9872703B2/en
Priority to US14/798,182 priority patent/US10413282B2/en
Priority to US15/615,596 priority patent/US11298202B2/en
Priority to US16/571,937 priority patent/US20200022686A1/en
Assigned to TELEFLEX LIFE SCIENCES LIMITED reassignment TELEFLEX LIFE SCIENCES LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: TELEFLEX MEDICAL DEVICES S.À R.L.
Abandoned legal-status Critical Current

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Definitions

  • the present invention is related to an apparatus and method for withdrawing specimens from the bone or bone marrow.
  • the apparatus and method can be used to extract stem cells or bone marrow for transplantation or diagnostic purposes.
  • bone marrow There are many clinical conditions where it is important to be able to access and retrieve bone marrow. In some cases it may be necessary to treat diseases with a bone marrow or stem cell transplant to restore functioning blood cells in the body after high-dose chemotherapy. Such conditions may include acute leukemias, brain tumors, breast cancer, Hodgkin's disease, multiple myeloma, neuroblastoma, non-Hodgkin's lymphomas, ovarian cancer, sarcoma and testicular cancer. In other cases it is necessary to access the bone marrow to obtain a sample of the marrow for diagnostic testing. These conditions may include cancer of any type and hematologic disease of any origin.
  • the devices available for gaining access to the medullary cavity of the bone, where the bone marrow is located include a trocar-fitted needle, with handles to facilitate application of pressure and rotation.
  • These types of devices require substantial force to break through the outer cortex of the bone by a fracturing technique.
  • the exertion of high pressure upon the needle causes pain for the patient and often damages the tip of the needle. This is particularly a problem when harvesting from the sternum of a patient because the excess force can cause penetration through the sternum and can damage underlying structures such as the heart and great vessels.
  • Another disadvantage of current techniques to access the bone marrow is that frequently more than one penetration site into the bone is required to retrieve enough bone marrow to either perform diagnostic tests or for transplantation purposes.
  • a physician may need to put the needle into several different parts of the pelvis which may require up to six needle puncture sites or more.
  • This multiple-pass requirement can be extremely painful for a patient and may deter people from donating bone marrow.
  • This technique of using multiple passes can also cause fatigue in smaller operators who may lack strength to complete multiple-pass procedures.
  • the apparatus includes a housing and a hollow drive shaft operable to engage a gear assembly.
  • the hollow drive shaft includes a first end operable to penetrate the bone and a second end operable to allow retrieval of portions of bone and bone marrow.
  • the hollow drive shaft also includes an inner channel operable to convey portions of bone and bone marrow.
  • the apparatus also includes a removable trocar with a first end operable to penetrate the bone and a second end.
  • the removable trocar includes an inner channel operable to convey portions of bone and bone marrow.
  • the gear assembly is able to engage and rotate the hollow drive shaft.
  • a motor operable to engage the gear assembly and drive the hollow drive shaft into the bone marrow by rotation of the hollow drive shaft and a power supply and associated circuitry operable to power the motor are also included.
  • an apparatus for removing portions of bone and bone marrow from a bone for diagnostic or therapeutic purposes includes a housing and a hollow drive shaft operable to engage a gear assembly.
  • the hollow drive shaft includes a first end operable to attach to a penetrator and a second end operable to allow retrieval of portions of bone marrow.
  • the hollow drive shaft also includes an inner channel operable to convey portions of bone marrow to an operator.
  • the detachable penetrator is able to penetrate the bone marrow and collect specimens of bone marrow.
  • a trocar having a first end operable to penetrate the bone marrow and a second end. The trocar can be removably inserted into the inner channel of the hollow drive shaft.
  • a connector operable to releasably attach the penetrator to a hollow drive shaft is also included.
  • a gear assembly operable to engage and rotate the hollow drive shaft is provided.
  • a motor operable to engage the reduction gear assembly and drive the penetrator into the bone marrow by rotation of the hollow drive shaft and a power supply and associated circuitry operable to power the motor are also provided.
  • a hollow drive shaft assembly operable to remove bone or tissue from a bone marrow.
  • An outer hollow drive shaft and a removable inner trocar operable to penetrate the bone marrow are included.
  • the outer hollow drive shaft is removably coupled to a gear assembly and the outer hollow drive shaft includes an inner channel operable to convey portions of bone and bone marrow.
  • a method for performing a bone marrow biopsy includes inserting a hollow drive shaft and trocar into the bone marrow by means of a powered apparatus.
  • the trocar may be removed from the hollow drive shaft and suction may be applied to an inner channel of the hollow drive shaft so that portions of bone and bone marrow may be retrieved from the inner channel of the hollow drive shaft.
  • An alternative method of performing a bone marrow biopsy includes attaching a penetrator to a hollow drive shaft and inserting an inner trocar into the hollow drive shaft and penetrator.
  • the penetrator is then inserted into the bone marrow by a powered apparatus.
  • the inner trocar is removed from the hollow drive shaft and penetrator, and suction may be applied to the inner channel of the hollow drive shaft to retrieve portions of bone marrow.
  • the site of bone marrow biopsy is controlled by a second end of the trocar comprising a ratcheted gear operable to control the depth of sampling from the bone marrow.
  • a method of harvesting bone marrow for transplantation includes inserting a hollow drive shaft and inner trocar into the bone marrow by means of a powered apparatus coupled with the hollow drive shaft.
  • the inner trocar is removed from the hollow drive shaft.
  • a suction is then applied to the inner channel of the hollow drive shaft to retrieve portions of bone marrow.
  • the inner trocar may be replaced into the hollow drive shaft.
  • the steps of removing the inner trocar from the hollow drive shaft and applying suction to the inner channel of the hollow drive shaft to retrieve portions of bone marrow may be repeated until a sufficient quantity of bone marrow has been harvested for bone marrow transplantation.
  • the site of harvest within the bone marrow may be changed by a ratcheted gear attached to the second end of the trocar.
  • the gear may be used to change the depth of sampling from the bone marrow.
  • FIG. 1A illustrates an embodiment of an apparatus for removing a bone marrow sample shown in longitudinal cross section.
  • FIG. 1B illustrates an embodiment of a hollow drive shaft of the current invention.
  • FIG. 1C illustrates an embodiment of a trocar of the current invention.
  • FIG. 1D illustrates an embodiment of an apparatus of the current invention.
  • FIG. 1E illustrates an embodiment of an apparatus for removing a bone marrow sample shown in longitudinal cross section.
  • FIG. 2A illustrates an example of a hollow drive shaft or penetrator of the current invention.
  • FIG. 2B illustrates an example of a hollow drive shaft or penetrator of the current invention.
  • FIG. 2C illustrates an example of an inner trocar of the current invention.
  • FIG. 2D illustrates an example of a hollow drive shaft or penetrator of the current invention.
  • FIG. 3A illustrates an example of an attachment of the current invention.
  • FIG. 3B is an illustration of an attachment of the current invention.
  • FIG. 4A is an illustration of a hollow drive shaft and trocar of the current invention.
  • FIG. 4B is an illustration of a hollow drive shaft and trocar of the current invention.
  • FIG. 4C is an illustration of a hollow drive shaft and trocar of the current invention in cross section.
  • FIG. 4D is an illustration of a hollow drive shaft and trocar of the current invention in cross section.
  • FIGS. 5 A-C illustrates example gear assemblies of the current invention.
  • FIGS. 1 A- 5 C Preferred embodiments of the invention and its advantages are best understood by reference to FIGS. 1 A- 5 C herein like numbers refer to same and like parts.
  • FIG. 1A illustrates an example of an apparatus for removing bone marrow from a bone.
  • Apparatus 10 may be used to obtain a sample of bone marrow from any suitable bone in the body such as the iliac crest or the sternum.
  • apparatus 10 includes housing 12 , a hollow drive shaft 14 , removable trocar 19 , gear assembly 37 , motor 38 and power supply 39 .
  • Housing 12 may include on/off switch 3 handle 5 and guard 6 .
  • Handle 5 may be angled downward to allow ease of operation and also to allow end of hollow drive shaft 14 to turn without obstruction from a hand.
  • Housing 12 encompasses power source 39 , motor 38 and associated circuitry 18 , hollow drive shaft 14 and gear assembly 37 .
  • Hollow drive shaft 14 includes inner channel 15 and collar 16 .
  • Gear 17 of gear assembly 37 engages collar 16 of hollow drill shaft 14 and thereby rotates hollow drive shaft 14 .
  • Removable trocar 19 may be inserted into inner channel 15 of hollow drive shaft 14 .
  • Trocar 19 is hollow and has an inner channel operable to convey bone and bone marrow samples.
  • Trocar 19 may have a handle 8 that can be used to tighten trocar 19 in place or to remove it from inner channel 15 of hollow drive shaft 14 .
  • Hollow drive shaft 14 may include luer lock connector 4 at the point where it exits housing 12 .
  • a luer lock connector may allow hollow drive shaft to connect to a suction apparatus such as a tubing or syringe or to any other suitable apparatus that would assist in obtaining a bone or bone marrow biopsy specimen.
  • An access port such as a suction port may also releasably attach to an end of hollow drive shaft where it exits housing 12 , for example to a luer lock connector.
  • Such an attachment may be a plug, a port, a suction apparatus, swivel port or other adapter.
  • FIG. 1B shows hollow drive shaft 14 removed from apparatus 10 .
  • hollow drive shaft 14 may include one or more thrust bearings 21 . Thrust bearings may absorb pressure from the thrust of a drive shaft into bone during drilling.
  • side ports shown in further detail in FIG. 2.
  • FIG. 1C illustrates removable trocar 19 which includes handle 8 . Handle 8 may be formed into a shape that is easily grasped and turned during the process of obtaining a biopsy.
  • Removable trocar 19 may include one or more side ports operable to access a bone marrow specimen shown in greater detail in FIG. 2.
  • housing 12 may include a releasable hatch or door 12 a that may be opened to allow hollow drive shaft and attached gear 17 to be removed after use of apparatus 10 .
  • a releasable hatch or door 12 a may be opened to allow hollow drive shaft and attached gear 17 to be removed after use of apparatus 10 .
  • This may be desirable where apparatus 10 is reusable and hollow drill shaft 14 and removable trocar 19 are disposable.
  • a releasable hatch or door may also be desirable to clean the inside of apparatus 10 .
  • detachable penetrator 20 may be attached to hollow drive shaft 14 by means of connector 36 and drilled into bone 2 .
  • removable trocar 19 may be inserted into inner channel 15 of hollow drive shaft 14 and into the hollow channel of penetrator 20 .
  • Penetrator 20 may include side ports to permit access to bone and bone marrow samples during a biopsy or bone marrow harvest procedure.
  • connector 36 includes an inner channel operable to allow retrieval of bone and bone marrow specimens.
  • FIGS. 2 A-D show an end 22 of either a hollow drive shaft or a penetrator that is suitable to penetrate a bone.
  • FIG. 2A illustrates hollow drive shaft or penetrator end 22 which may include multiple sampling ports 23 through which bone marrow or other biopsy material may be aspirated. Sampling ports 23 a , 23 b and 23 c are each operable to retrieve a portion of bone marrow.
  • sampling port 13 of removable trocar end 24 may align with sampling port 23 a , 23 b , or 23 c .
  • Hollow drive shaft or penetrator end 22 may include serrated tip 25 as shown in FIG. 2B or any other suitable configuration for sampling bone or bone marrow.
  • FIG. 2C shows removable trocar end 24 having a sampling port 23 near tip 27 through which a sample of bone or bone marrow can be retrieved as well as through a sampling port 23 a , 23 b or 23 c .
  • sampling port 23 a , 23 b or 23 c of hollow drive shaft or penetrator 22 is aligned with sampling port 13 of removable trocar 24 , a portion of bone marrow may be suctioned out of the bone.
  • Removable trocar 24 may be removed allowing bone marrow to be suctioned through one or more sampling ports 23 of hollow drive shaft or penetrator 22 at different sites in a bone marrow cavity sequentially.
  • FIG. 2D shows another example of tip 25 of hollow drive shaft or penetrator end 22 having internal threads 26 that are able to engage a specimen of bone and core it out as hollow drive shaft or penetrator 22 is drilled into bone. Threads 26 may engage and adhere to a portion of bone or to a semisolid substance such as bone marrow and maintain contact with the specimen so it may be successfully retrieved.
  • FIG. 3A shows operating mechanism 32 that may be included in some embodiments of the invention and may be attached to hollow drive shaft 14 and manipulated to change the depth in a bone marrow where sampling occurs.
  • Operating mechanism 32 includes handle 35 and gear 33 .
  • Gear 33 engages gear 34 attached to trocar 19 .
  • Suction port 28 shown attached to trocar 19 , may be used to retrieve portions of bone marrow from inner channel 15 of hollow drive shaft 14 .
  • FIG. 3B shows an example suction port 28 that may be connected to trocar 19 where it exits housing 12 .
  • a suction port or suction swivel apparatus may also be connected to the hollow drive shaft 14 .
  • This feature allows a suction apparatus of the type well known to one skilled in the art to be used to obtain bone marrow samples.
  • Suction port 28 may also be configured to attach directly to a penetrator for example in an embodiment of the invention where the penetrator is detached from the housing before it is accessed for bone marrow retrieval.
  • a suction swivel apparatus 45 that allows a suction tube 41 to attach to suction port 28 .
  • Suction swivel apparatus 45 allows suction port 28 to remain attached to suction tube 41 while an attached drilling apparatus is drilling into bone marrow without kinking or twisting suction tube 41 . Also shown in FIG. 3B is receptacle 43 that is interposed between suction tube 41 and a source of suction such that a bone marrow specimen may be successfully retrieved into receptacle 43 and not lost into a suction machine.
  • FIGS. 4 A-D shows an example hollow drive shaft end or penetrator end 44 and inner trocar 42 having a split-needle configuration.
  • An inner trocar 42 is inserted into a hollow drive shaft or penetrator end 44 .
  • Inner trocar 42 shown in the open position in FIG. 4A is advanced past the end of hollow drive shaft end or penetrator end 44 where it may be opened and inserted into bone, bone marrow or other tissue.
  • Inner trocar 42 may be closed, shown in FIG. 4B, so that a specimen is retained in its grasp as it is withdrawn from the body.
  • FIG. 4C shows a cross section of the split-needle inner trocar 42 where the tip of the inner trocar 42 is in the open position.
  • FIG. 4D shows a cross section of the trocar 42 is shown in the closed position.
  • the apparatus may or may not include a reduction gear assembly.
  • a reduction gear assembly may include a worm gear assembly shown in more detail in FIG. 5A and may include first connector 50 that connects shaft 52 of motor 38 to worm gear 54 .
  • a reduction gear assembly may be used to decrease the RPMs between the motor and penetrator assembly to provide an optimum RPM at the point of insertion of penetrator assembly into bone.
  • FIG. 5B illustrates a further embodiment of a reduction gear assembly wherein a first spur gear 57 engages a second spur gear 58 .
  • FIG. 5C illustrates an alternate embodiment of a reduction gear assembly wherein spur gear 56 is offset forty-five degrees relative to hollow drive shaft 14 which may be preferable in some embodiments of the present invention.
  • spur gear 58 may be offset at any angle and is not limited to forty-five degrees.
  • Other gears may be used in a reduction gear assembly, for example a planetary gear (not expressly shown) may be used alone or in combination with a worm gear or a spur gear.

Abstract

An apparatus for removing portions of bone marrow from a bone is provided. The apparatus includes a housing and a hollow drive shaft operable to engage a gear assembly. The hollow drive shaft includes a first end operable to penetrate the bone and a second end operable to allow retrieval of portions of bone and bone marrow. The apparatus also includes a removable trocar. The removable trocar includes an inner channel operable to convey portions of bone and bone marrow. The gear assembly is able to engage and rotate the hollow drive shaft. A motor operable to drive the hollow drive shaft into the bone marrow by rotation of the hollow drive shaft and a power supply and associated circuitry operable to power the motor are also included.

Description

    RELATED APPLICATION
  • This application claims priority to U.S. Provisional Patent Application Serial No. 60/384756, filed May 31, 2002, and entitled “Apparatus and Method to Provide Access to Bone Marrow”[0001]
  • This application is copending to patent application entitled, “Apparatus and Method To Provide Access To Bone Marrow”, Ser. No. ______, filed ______; and copending to patent application entitled “Apparatus and Method to Access Bone Marrow”, Ser. No. ______, filed ______, which claim priority from the same provisional application.[0002]
  • TECHNICAL FIELD
  • The present invention is related to an apparatus and method for withdrawing specimens from the bone or bone marrow. The apparatus and method can be used to extract stem cells or bone marrow for transplantation or diagnostic purposes. [0003]
  • BACKGROUND OF THE INVENTION
  • There are many clinical conditions where it is important to be able to access and retrieve bone marrow. In some cases it may be necessary to treat diseases with a bone marrow or stem cell transplant to restore functioning blood cells in the body after high-dose chemotherapy. Such conditions may include acute leukemias, brain tumors, breast cancer, Hodgkin's disease, multiple myeloma, neuroblastoma, non-Hodgkin's lymphomas, ovarian cancer, sarcoma and testicular cancer. In other cases it is necessary to access the bone marrow to obtain a sample of the marrow for diagnostic testing. These conditions may include cancer of any type and hematologic disease of any origin. [0004]
  • Current techniques for gaining access to bone marrow can be difficult, traumatic and occasionally dangerous, depending on the site selected for harvest, the operator's expertise and the patient's anatomy. In general, the devices available for gaining access to the medullary cavity of the bone, where the bone marrow is located, include a trocar-fitted needle, with handles to facilitate application of pressure and rotation. These types of devices require substantial force to break through the outer cortex of the bone by a fracturing technique. The exertion of high pressure upon the needle causes pain for the patient and often damages the tip of the needle. This is particularly a problem when harvesting from the sternum of a patient because the excess force can cause penetration through the sternum and can damage underlying structures such as the heart and great vessels. [0005]
  • Another disadvantage of current techniques to access the bone marrow is that frequently more than one penetration site into the bone is required to retrieve enough bone marrow to either perform diagnostic tests or for transplantation purposes. To retrieve an adequate sample of bone marrow for either a bone marrow or stem cell transplant, a physician may need to put the needle into several different parts of the pelvis which may require up to six needle puncture sites or more. This multiple-pass requirement can be extremely painful for a patient and may deter people from donating bone marrow. This technique of using multiple passes can also cause fatigue in smaller operators who may lack strength to complete multiple-pass procedures. [0006]
  • Retrieving bone samples for diagnostic purposes is likewise difficult. Occasionally the core sample of bone is not retrieved because it is not extracted successfully with a standard biopsy needle. Thus, multiple attempts may be necessary to obtain a satisfactory bone or bone marrow biopsy. [0007]
  • Current techniques require that biopsy needles be forced by manual pressure into bone. These techniques may have undesirable side effects such as damaging a needle tip or having the needle slide off the proposed bone target and into organs or soft tissues. [0008]
  • SUMMARY OF THE INVENTION
  • There is a need for an apparatus and method to access the bone marrow that is minimally traumatic to the patient and that allows a sufficient amount of bone marrow to be removed the first time the bone is penetrated. In accordance with teachings of the present invention, an apparatus and method for the removal of portions of bone marrow from a bone are provided. [0009]
  • In one embodiment the apparatus includes a housing and a hollow drive shaft operable to engage a gear assembly. The hollow drive shaft includes a first end operable to penetrate the bone and a second end operable to allow retrieval of portions of bone and bone marrow. The hollow drive shaft also includes an inner channel operable to convey portions of bone and bone marrow. The apparatus also includes a removable trocar with a first end operable to penetrate the bone and a second end. The removable trocar includes an inner channel operable to convey portions of bone and bone marrow. The gear assembly is able to engage and rotate the hollow drive shaft. A motor operable to engage the gear assembly and drive the hollow drive shaft into the bone marrow by rotation of the hollow drive shaft and a power supply and associated circuitry operable to power the motor are also included. [0010]
  • In another embodiment, an apparatus for removing portions of bone and bone marrow from a bone for diagnostic or therapeutic purposes is provided that includes a housing and a hollow drive shaft operable to engage a gear assembly. The hollow drive shaft includes a first end operable to attach to a penetrator and a second end operable to allow retrieval of portions of bone marrow. The hollow drive shaft also includes an inner channel operable to convey portions of bone marrow to an operator. The detachable penetrator is able to penetrate the bone marrow and collect specimens of bone marrow. Also included is a trocar having a first end operable to penetrate the bone marrow and a second end. The trocar can be removably inserted into the inner channel of the hollow drive shaft. A connector operable to releasably attach the penetrator to a hollow drive shaft is also included. A gear assembly operable to engage and rotate the hollow drive shaft is provided. A motor operable to engage the reduction gear assembly and drive the penetrator into the bone marrow by rotation of the hollow drive shaft and a power supply and associated circuitry operable to power the motor are also provided. [0011]
  • In a further embodiment of the invention a hollow drive shaft assembly operable to remove bone or tissue from a bone marrow is provided. An outer hollow drive shaft and a removable inner trocar operable to penetrate the bone marrow are included. The outer hollow drive shaft is removably coupled to a gear assembly and the outer hollow drive shaft includes an inner channel operable to convey portions of bone and bone marrow. [0012]
  • In a further embodiment of the invention a method for performing a bone marrow biopsy is provided that includes inserting a hollow drive shaft and trocar into the bone marrow by means of a powered apparatus. The trocar may be removed from the hollow drive shaft and suction may be applied to an inner channel of the hollow drive shaft so that portions of bone and bone marrow may be retrieved from the inner channel of the hollow drive shaft. [0013]
  • An alternative method of performing a bone marrow biopsy is provided that includes attaching a penetrator to a hollow drive shaft and inserting an inner trocar into the hollow drive shaft and penetrator. The penetrator is then inserted into the bone marrow by a powered apparatus. The inner trocar is removed from the hollow drive shaft and penetrator, and suction may be applied to the inner channel of the hollow drive shaft to retrieve portions of bone marrow. In a particular embodiment of the invention the site of bone marrow biopsy is controlled by a second end of the trocar comprising a ratcheted gear operable to control the depth of sampling from the bone marrow. [0014]
  • In a further embodiment of the invention, a method of harvesting bone marrow for transplantation is provided that includes inserting a hollow drive shaft and inner trocar into the bone marrow by means of a powered apparatus coupled with the hollow drive shaft. The inner trocar is removed from the hollow drive shaft. A suction is then applied to the inner channel of the hollow drive shaft to retrieve portions of bone marrow. The inner trocar may be replaced into the hollow drive shaft. The steps of removing the inner trocar from the hollow drive shaft and applying suction to the inner channel of the hollow drive shaft to retrieve portions of bone marrow may be repeated until a sufficient quantity of bone marrow has been harvested for bone marrow transplantation. [0015]
  • In a particular embodiment of the invention, the site of harvest within the bone marrow may be changed by a ratcheted gear attached to the second end of the trocar. The gear may be used to change the depth of sampling from the bone marrow. [0016]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • A more complete and thorough understanding of the present embodiments and advantages thereof may be acquired by referring to the following description taken in conjunction with the accompanying drawings, in which like reference numbers indicate like features, and wherein: [0017]
  • FIG. 1A illustrates an embodiment of an apparatus for removing a bone marrow sample shown in longitudinal cross section. [0018]
  • FIG. 1B illustrates an embodiment of a hollow drive shaft of the current invention. [0019]
  • FIG. 1C illustrates an embodiment of a trocar of the current invention. [0020]
  • FIG. 1D illustrates an embodiment of an apparatus of the current invention. [0021]
  • FIG. 1E illustrates an embodiment of an apparatus for removing a bone marrow sample shown in longitudinal cross section. [0022]
  • FIG. 2A illustrates an example of a hollow drive shaft or penetrator of the current invention. [0023]
  • FIG. 2B illustrates an example of a hollow drive shaft or penetrator of the current invention. [0024]
  • FIG. 2C illustrates an example of an inner trocar of the current invention. [0025]
  • FIG. 2D illustrates an example of a hollow drive shaft or penetrator of the current invention. [0026]
  • FIG. 3A illustrates an example of an attachment of the current invention. [0027]
  • FIG. 3B is an illustration of an attachment of the current invention. [0028]
  • FIG. 4A is an illustration of a hollow drive shaft and trocar of the current invention. [0029]
  • FIG. 4B is an illustration of a hollow drive shaft and trocar of the current invention. [0030]
  • FIG. 4C is an illustration of a hollow drive shaft and trocar of the current invention in cross section. [0031]
  • FIG. 4D is an illustration of a hollow drive shaft and trocar of the current invention in cross section. [0032]
  • FIGS. [0033] 5A-C illustrates example gear assemblies of the current invention.
  • DETAILED DESCRIPTION OF THE INVENTION
  • Preferred embodiments of the invention and its advantages are best understood by reference to FIGS. [0034] 1A-5C herein like numbers refer to same and like parts.
  • FIG. 1A, illustrates an example of an apparatus for removing bone marrow from a bone. [0035] Apparatus 10 may be used to obtain a sample of bone marrow from any suitable bone in the body such as the iliac crest or the sternum. In one embodiment, apparatus 10 includes housing 12, a hollow drive shaft 14, removable trocar 19, gear assembly 37, motor 38 and power supply 39. Housing 12 may include on/off switch 3 handle 5 and guard 6. Handle 5 may be angled downward to allow ease of operation and also to allow end of hollow drive shaft 14 to turn without obstruction from a hand. Housing 12 encompasses power source 39, motor 38 and associated circuitry 18, hollow drive shaft 14 and gear assembly 37. Hollow drive shaft 14 includes inner channel 15 and collar 16. Gear 17 of gear assembly 37 engages collar 16 of hollow drill shaft 14 and thereby rotates hollow drive shaft 14.
  • [0036] Removable trocar 19 may be inserted into inner channel 15 of hollow drive shaft 14. Trocar 19 is hollow and has an inner channel operable to convey bone and bone marrow samples. Trocar 19 may have a handle 8 that can be used to tighten trocar 19 in place or to remove it from inner channel 15 of hollow drive shaft 14. Hollow drive shaft 14 may include luer lock connector 4 at the point where it exits housing 12. A luer lock connector may allow hollow drive shaft to connect to a suction apparatus such as a tubing or syringe or to any other suitable apparatus that would assist in obtaining a bone or bone marrow biopsy specimen. An access port, such as a suction port may also releasably attach to an end of hollow drive shaft where it exits housing 12, for example to a luer lock connector. Such an attachment may be a plug, a port, a suction apparatus, swivel port or other adapter.
  • FIG. 1B shows [0037] hollow drive shaft 14 removed from apparatus 10. In one embodiment, hollow drive shaft 14 may include one or more thrust bearings 21. Thrust bearings may absorb pressure from the thrust of a drive shaft into bone during drilling. Also included in hollow drive shaft are side ports shown in further detail in FIG. 2. FIG. 1C illustrates removable trocar 19 which includes handle 8. Handle 8 may be formed into a shape that is easily grasped and turned during the process of obtaining a biopsy. Removable trocar 19 may include one or more side ports operable to access a bone marrow specimen shown in greater detail in FIG. 2.
  • In one embodiment, shown in FIG. 1D, [0038] housing 12 may include a releasable hatch or door 12 a that may be opened to allow hollow drive shaft and attached gear 17 to be removed after use of apparatus 10. This may be desirable where apparatus 10 is reusable and hollow drill shaft 14 and removable trocar 19 are disposable. A releasable hatch or door may also be desirable to clean the inside of apparatus 10.
  • In another embodiment of the current invention, shown in FIG. 1E, [0039] detachable penetrator 20 may be attached to hollow drive shaft 14 by means of connector 36 and drilled into bone 2. In this embodiment, removable trocar 19 may be inserted into inner channel 15 of hollow drive shaft 14 and into the hollow channel of penetrator 20. Penetrator 20 may include side ports to permit access to bone and bone marrow samples during a biopsy or bone marrow harvest procedure. One advantage of an embodiment that includes a detachable penetrator is it allows penetrators of various sizes and configurations to be attached to hollow drive shaft 14. In this embodiment, connector 36 includes an inner channel operable to allow retrieval of bone and bone marrow specimens.
  • FIGS. [0040] 2A-D show an end 22 of either a hollow drive shaft or a penetrator that is suitable to penetrate a bone. FIG. 2A, illustrates hollow drive shaft or penetrator end 22 which may include multiple sampling ports 23 through which bone marrow or other biopsy material may be aspirated. Sampling ports 23 a, 23 b and 23 c are each operable to retrieve a portion of bone marrow. When removable trocar end 24 is in position within inner channel of hollow drive shaft end 22 sampling port 13 of removable trocar end 24 may align with sampling port 23 a, 23 b, or 23 c. An operator may determine the level in the bone marrow where a specimen is taken or which sampling port (23 a, 23 b or 23 c) to align with trocar sampling port 13. Hollow drive shaft or penetrator end 22 may include serrated tip 25 as shown in FIG. 2B or any other suitable configuration for sampling bone or bone marrow.
  • FIG. 2C shows [0041] removable trocar end 24 having a sampling port 23 near tip 27 through which a sample of bone or bone marrow can be retrieved as well as through a sampling port 23 a, 23 b or 23 c. When sampling port 23 a, 23 b or 23 c of hollow drive shaft or penetrator 22 is aligned with sampling port 13 of removable trocar 24, a portion of bone marrow may be suctioned out of the bone. Removable trocar 24 may be removed allowing bone marrow to be suctioned through one or more sampling ports 23 of hollow drive shaft or penetrator 22 at different sites in a bone marrow cavity sequentially. FIG. 2D shows another example of tip 25 of hollow drive shaft or penetrator end 22 having internal threads 26 that are able to engage a specimen of bone and core it out as hollow drive shaft or penetrator 22 is drilled into bone. Threads 26 may engage and adhere to a portion of bone or to a semisolid substance such as bone marrow and maintain contact with the specimen so it may be successfully retrieved.
  • FIG. 3A shows operating [0042] mechanism 32 that may be included in some embodiments of the invention and may be attached to hollow drive shaft 14 and manipulated to change the depth in a bone marrow where sampling occurs. Operating mechanism 32 includes handle 35 and gear 33. Gear 33 engages gear 34 attached to trocar 19. Suction port 28, shown attached to trocar 19, may be used to retrieve portions of bone marrow from inner channel 15 of hollow drive shaft 14.
  • FIG. 3B shows an [0043] example suction port 28 that may be connected to trocar 19 where it exits housing 12. In one embodiment of the invention a suction port or suction swivel apparatus may also be connected to the hollow drive shaft 14. This feature allows a suction apparatus of the type well known to one skilled in the art to be used to obtain bone marrow samples. Suction port 28 may also be configured to attach directly to a penetrator for example in an embodiment of the invention where the penetrator is detached from the housing before it is accessed for bone marrow retrieval. Also shown in FIG. 3B is a suction swivel apparatus 45 that allows a suction tube 41 to attach to suction port 28. Suction swivel apparatus 45 allows suction port 28 to remain attached to suction tube 41 while an attached drilling apparatus is drilling into bone marrow without kinking or twisting suction tube 41. Also shown in FIG. 3B is receptacle 43 that is interposed between suction tube 41 and a source of suction such that a bone marrow specimen may be successfully retrieved into receptacle 43 and not lost into a suction machine.
  • FIGS. [0044] 4A-D shows an example hollow drive shaft end or penetrator end 44 and inner trocar 42 having a split-needle configuration. An inner trocar 42 is inserted into a hollow drive shaft or penetrator end 44. Inner trocar 42 shown in the open position in FIG. 4A is advanced past the end of hollow drive shaft end or penetrator end 44 where it may be opened and inserted into bone, bone marrow or other tissue. Inner trocar 42 may be closed, shown in FIG. 4B, so that a specimen is retained in its grasp as it is withdrawn from the body. FIG. 4C shows a cross section of the split-needle inner trocar 42 where the tip of the inner trocar 42 is in the open position. FIG. 4D shows a cross section of the trocar 42 is shown in the closed position.
  • The apparatus may or may not include a reduction gear assembly. A reduction gear assembly may include a worm gear assembly shown in more detail in FIG. 5A and may include [0045] first connector 50 that connects shaft 52 of motor 38 to worm gear 54. A reduction gear assembly may be used to decrease the RPMs between the motor and penetrator assembly to provide an optimum RPM at the point of insertion of penetrator assembly into bone. FIG. 5B illustrates a further embodiment of a reduction gear assembly wherein a first spur gear 57 engages a second spur gear 58. FIG. 5C illustrates an alternate embodiment of a reduction gear assembly wherein spur gear 56 is offset forty-five degrees relative to hollow drive shaft 14 which may be preferable in some embodiments of the present invention. In this embodiment spur gear 58 may be offset at any angle and is not limited to forty-five degrees. Other gears may be used in a reduction gear assembly, for example a planetary gear (not expressly shown) may be used alone or in combination with a worm gear or a spur gear.
  • Although the present invention and its advantages have been described in detail, it should be understood that various changes, substitutions and alternations can be made herein without departing from the spirit and scope of the invention as defined by the following claims. [0046]

Claims (37)

What is claimed is:
1. An apparatus for removing portions of bone and bone marrow from a bone for diagnostic or therapeutic purposes comprising:
a housing;
a hollow drive shaft operable to engage a gear assembly;
the hollow drive shaft comprising a first end operable to penetrate the bone and a second end operable to allow retrieval of portions of bone and bone marrow;
the hollow drive shaft further comprising an inner channel operable to convey portions of bone and bone marrow;
a removable trocar comprising a first end operable to penetrate the bone and a second end;
the removable trocar further comprising an inner channel operable to convey portions of bone and bone marrow;
the gear assembly operable to engage the hollow drive shaft;
a motor, coupled to the hollow drive shaft, operable to drive the penetrator into the bone marrow by rotation of the hollow drive shaft; and
a power supply and associated circuitry operable to power the motor.
2. The apparatus of claim 1 wherein the hollow drive shaft and removable trocar are disposable and operable to be removed from the apparatus through a releasably coupled access panel in the housing.
3. The apparatus of claim 1 wherein the hollow drive shaft is operable to attach to an access port.
4. The apparatus of claim 1 wherein the hollow drive shaft is operable to attach to a suction port.
5. The apparatus of claim 1 wherein the second end of the trocar is coupled to a ratcheted gear the gear operable to align the sampling ports of the trocar with the sampling ports of the hollow drive shaft.
6. The apparatus of claim 1 wherein the removable trocar comprises a tip having a longitudinal groove operable to release bone chips from an insertion site into the bone marrow and the outer penetrator includes a cutting edge.
7. The apparatus of claim 1 wherein the housing comprises a portion of a base mounted on a surface.
8. The apparatus of claim 1 wherein the hollow drive shaft comprises a tip having internal threads operable to engage a bone or bone marrow biopsy specimen as it is removed from the bone marrow.
9. The apparatus of claim 1 wherein the removable trocar comprises a tip having two separate longitudinal pieces that can move together or apart.
10. The apparatus of claim 1 further comprising a reduction gear assembly operable to rotate the hollow drive shaft.
11. The apparatus of claim 1 wherein the hollow drive shaft comprises at least one thrust bearing.
12. The apparatus of claim 1 wherein the hollow drive shaft comprises at least one side port operable to access a portion of bone or bone marrow.
13. The apparatus of claim 1 wherein the removable trocar comprises at least one side port operable to align with a side port of the hollow drive shaft to access a portion of bone or bone marrow.
14. The apparatus of claim 1 wherein the hollow drive shaft comprises a luer lock connector.
15. The apparatus of claim 1 wherein the inner trocar comprises two longitudinal bodies, the longitudinal bodies having tips with jaws operable to grasp a portion of bone or bone marrow and wherein the longitudinal bodies are operable to separate or come together depending on their position relative to the hollow drive shaft.
16. An apparatus for removing portions of bone and bone marrow from a bone for diagnostic or therapeutic purposes comprising:
a housing;
a hollow drive shaft disposed in the housing;
the hollow drive shaft operable to engage a gear assembly;
the hollow drive shaft comprising a first end operable to attach to a penetrator and a second end operable to allow retrieval of portions of bone marrow;
the hollow drive shaft further comprising an inner channel operable to convey portions of bone marrow to an operator;
a detachable penetrator operable to penetrate the bone marrow and collect specimens of bone marrow;
a trocar having a first end operable to penetrate the bone marrow and a second end;
the trocar operable to removably insert into the inner channel of the hollow drive shaft;
a connector operable to releasably attach the penetrator to the hollow drive shaft;
a gear assembly operable to rotate the hollow drive shaft;
a motor coupled to the hollow drive shaft operable to drive the penetrator into the bone marrow by rotation of the hollow drive shaft; and
a power supply and associated circuitry operable to power the motor.
17. The apparatus of claim 16 wherein the trocar comprises a tip having a longitudinal groove operable to release bone chips from an insertion site into the bone marrow.
18. The apparatus of claim 16 wherein the second end of the hollow drive shaft comprises an access port operable to be used to obtain portions of bone and bone marrow from the inner channel.
19. The apparatus of claim 16 wherein the second end of the hollow drive shaft comprises a suction port to remove portions of bone and bone marrow into a receptacle.
20. The apparatus of claim 16 wherein the second end of the trocar comprises a ratcheted gear operable to control the depth of sampling from the bone marrow.
21. The apparatus of claim 16 wherein the penetrator comprises internal threads operable to engage bone or bone marrow as the penetrator is drilled into the bone.
22. The apparatus of claim 16 wherein the penetrator comprises two separate longitudinal pieces that can move together to grasp a biopsy specimen.
23. The apparatus of claim 16 further comprising a reduction gear assembly operable to rotate the hollow drive shaft.
24. The apparatus of claim 16 wherein the hollow drive shaft comprises at least one thrust bearing.
25. The apparatus of claim 16 wherein the penetrator comprises at least one side port.
26. The apparatus of claim 16 wherein the removable trocar comprises at least one side port operable to align with a side port of the penetrator.
27. The apparatus of claim 16 wherein the hollow drive shaft comprises a luer lock connector.
28. A hollow drive shaft assembly operable to remove bone or bone marrow from a bone for diagnostic or therapeutic purposes comprising:
an outer hollow drive shaft, and a removable inner trocar operable to penetrate the bone marrow;
the outer hollow drive shaft removably coupled to a gear assembly; and
the outer hollow drive shaft further comprising an inner channel operable to convey portions of bone and bone marrow.
29. The hollow drive shaft assembly of claim 28 wherein the hollow drive shaft comprises a tip with serrated teeth, the hollow drive shaft further comprising internal threads operable to engage a portion of bone or bone marrow.
30. The hollow drive shaft assembly of claim 28 wherein the hollow drive shaft comprises a body with at least one side port operable to obtain portions of bone marrow.
31. The hollow drive shaft assembly of claim 28 wherein the inner trocar comprises a tip with a cutting edge and further comprises a body with at least one side port operable to obtain bone marrow tissue from the bone marrow.
32. The hollow drive shaft assembly of claim 28 wherein the inner trocar comprises:
two longitudinal bodies, the longitudinal bodies further comprising tips with curved jaws; and
the longitudinal bodies operable to separate or come together depending on their position relative to the outer penetrator, and further operable to grasp a portion of bone or bone marrow between the curved jaws.
33. A method for performing a bone marrow biopsy comprising:
inserting a hollow drive shaft and trocar into the bone marrow using a powered apparatus;
removing the inner trocar from an outer penetrator;
applying suction to an inner channel; and
retrieving portions of bone marrow from the inner channel of the hollow drive shaft.
34. The method of claim 33 further comprising limiting sampling of the trocar from the bone marrow by adjusting a ratchet gear coupled to the trocar.
35. A method of performing a bone marrow biopsy comprising:
attaching a penetrator to a hollow drive shaft;
inserting an inner trocar into the hollow drive shaft and penetrator;
inserting the penetrator into the bone marrow by rotating the drive shaft using an electric motor;
removing an inner trocar from the hollow drive shaft and penetrator;
applying suction to an inner channel of the hollow drive shaft; and
retrieving portions of bone marrow from the inner channel.
36. The method of claim 35 further comprising selecting portions of the bone marrow for removal by limiting longitudinal movement of the trocar.
37. A method of harvesting bone marrow for transplantation comprising:
inserting a hollow drive shaft and inner trocar into the bone marrow by means of a powered apparatus coupled with the hollow drive shaft;
removing the inner trocar from the hollow drive shaft and penetrator;
applying suction to the inner channel of the hollow drive shaft and retrieving portions of bone and bone marrow;
replacing the inner trocar into the hollow drive shaft and penetrator;
changing the site of harvest within the bone marrow by using a ratcheted gear attached to a second end of the trocar, the gear operable to change the depth of sampling from the bone marrow; and
repeating the steps of removing the inner trocar from the hollow drive shaft and applying suction to the inner channel of the hollow drive shaft to retrieve portions of bone marrow until a sufficient quantity of bone marrow has been harvested for bone marrow transplantation.
US10/448,650 2002-05-31 2003-05-30 Apparatus and method to access the bone marrow for oncology and stem cell applications Abandoned US20030225344A1 (en)

Priority Applications (17)

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US10/448,650 US20030225344A1 (en) 2002-05-31 2003-05-30 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/389,732 US20060167378A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/389,733 US20060167379A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/380,340 US9072543B2 (en) 2002-05-31 2006-04-26 Vascular access kits and methods
US11/427,501 US7951089B2 (en) 2002-05-31 2006-06-29 Apparatus and methods to harvest bone and bone marrow
US11/781,597 US20080015468A1 (en) 2002-05-31 2007-07-23 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/781,568 US20080015467A1 (en) 2002-05-31 2007-07-23 Apparatus and Method to Access the Bone Marrow for Oncology and Stem Cell Applications
US11/853,685 US7850620B2 (en) 2002-05-31 2007-09-11 Biopsy devices and related methods
US11/853,691 US9545243B2 (en) 2002-05-31 2007-09-11 Bone marrow aspiration devices and related methods
US12/259,745 US9078637B2 (en) 2002-05-31 2008-10-28 Apparatus and methods to harvest bone and bone marrow
US12/427,310 US8690791B2 (en) 2002-05-31 2009-04-21 Apparatus and method to access the bone marrow
US12/701,268 US20100137740A1 (en) 2002-05-31 2010-02-05 Apparatus and method to access the bone marrow for oncology and stem cell applications
US12/963,255 US9717564B2 (en) 2002-05-31 2010-12-08 Biopsy devices and related methods
US14/791,654 US9872703B2 (en) 2002-05-31 2015-07-06 Vascular access kits and methods
US14/798,182 US10413282B2 (en) 2002-05-31 2015-07-13 Apparatus and methods to harvest bone and bone marrow
US15/615,596 US11298202B2 (en) 2002-05-31 2017-06-06 Biopsy devices and related methods
US16/571,937 US20200022686A1 (en) 2002-05-31 2019-09-16 Apparatus and methods to harvest bone and bone marrow

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US38475602P 2002-05-31 2002-05-31
US10/448,650 US20030225344A1 (en) 2002-05-31 2003-05-30 Apparatus and method to access the bone marrow for oncology and stem cell applications

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US11/389,732 Division US20060167378A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/389,732 Continuation-In-Part US20060167378A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/389,733 Division US20060167379A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/427,501 Continuation-In-Part US7951089B2 (en) 2002-05-31 2006-06-29 Apparatus and methods to harvest bone and bone marrow
US12/427,310 Continuation-In-Part US8690791B2 (en) 2002-05-31 2009-04-21 Apparatus and method to access the bone marrow

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US10/449,503 Active 2026-09-02 US7670328B2 (en) 2002-05-31 2003-05-30 Apparatus and method to provide emergency access to bone marrow
US10/449,476 Active 2024-10-20 US7699850B2 (en) 2002-05-31 2003-05-30 Apparatus and method to access bone marrow
US10/448,650 Abandoned US20030225344A1 (en) 2002-05-31 2003-05-30 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/253,959 Active 2029-05-08 US8506568B2 (en) 2002-05-31 2005-10-19 Apparatus and method to access bone marrow
US11/253,467 Active 2028-09-03 US8876826B2 (en) 2002-05-31 2005-10-19 Apparatus and method to access bone marrow
US11/389,733 Abandoned US20060167379A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/389,732 Abandoned US20060167378A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/781,597 Abandoned US20080015468A1 (en) 2002-05-31 2007-07-23 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/781,568 Abandoned US20080015467A1 (en) 2002-05-31 2007-07-23 Apparatus and Method to Access the Bone Marrow for Oncology and Stem Cell Applications
US12/331,979 Active 2026-11-14 US8715287B2 (en) 2002-05-31 2008-12-10 Apparatus and method to provide emergency access to bone marrow
US12/701,268 Abandoned US20100137740A1 (en) 2002-05-31 2010-02-05 Apparatus and method to access the bone marrow for oncology and stem cell applications
US12/718,606 Active US8480632B2 (en) 2002-05-31 2010-03-05 Cartridge apparatus for injecting fluids into bone
US13/966,104 Expired - Lifetime US9314270B2 (en) 2002-05-31 2013-08-13 Apparatus and method to access bone marrow
US14/271,144 Expired - Lifetime US8992535B2 (en) 2002-05-31 2014-05-06 Apparatus and method to provide emergency access to bone marrow
US14/532,635 Active 2024-08-30 US10456149B2 (en) 2002-05-31 2014-11-04 Apparatus and method to access bone marrow
US14/666,391 Expired - Lifetime US9393031B2 (en) 2002-05-31 2015-03-24 Apparatus and method to provide emergency access to bone marrow
US15/064,175 Expired - Lifetime US10893875B2 (en) 2002-05-31 2016-03-08 Apparatus to access bone marrow
US16/664,282 Abandoned US20200054350A1 (en) 2002-05-31 2019-10-25 Apparatus and method to access bone marrow
US16/821,627 Expired - Lifetime US11324521B2 (en) 2002-05-31 2020-03-17 Apparatus and method to access bone marrow

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US11/389,733 Abandoned US20060167379A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/389,732 Abandoned US20060167378A1 (en) 2002-05-31 2006-03-27 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/781,597 Abandoned US20080015468A1 (en) 2002-05-31 2007-07-23 Apparatus and method to access the bone marrow for oncology and stem cell applications
US11/781,568 Abandoned US20080015467A1 (en) 2002-05-31 2007-07-23 Apparatus and Method to Access the Bone Marrow for Oncology and Stem Cell Applications
US12/331,979 Active 2026-11-14 US8715287B2 (en) 2002-05-31 2008-12-10 Apparatus and method to provide emergency access to bone marrow
US12/701,268 Abandoned US20100137740A1 (en) 2002-05-31 2010-02-05 Apparatus and method to access the bone marrow for oncology and stem cell applications
US12/718,606 Active US8480632B2 (en) 2002-05-31 2010-03-05 Cartridge apparatus for injecting fluids into bone
US13/966,104 Expired - Lifetime US9314270B2 (en) 2002-05-31 2013-08-13 Apparatus and method to access bone marrow
US14/271,144 Expired - Lifetime US8992535B2 (en) 2002-05-31 2014-05-06 Apparatus and method to provide emergency access to bone marrow
US14/532,635 Active 2024-08-30 US10456149B2 (en) 2002-05-31 2014-11-04 Apparatus and method to access bone marrow
US14/666,391 Expired - Lifetime US9393031B2 (en) 2002-05-31 2015-03-24 Apparatus and method to provide emergency access to bone marrow
US15/064,175 Expired - Lifetime US10893875B2 (en) 2002-05-31 2016-03-08 Apparatus to access bone marrow
US16/664,282 Abandoned US20200054350A1 (en) 2002-05-31 2019-10-25 Apparatus and method to access bone marrow
US16/821,627 Expired - Lifetime US11324521B2 (en) 2002-05-31 2020-03-17 Apparatus and method to access bone marrow

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Cited By (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225364A1 (en) * 2002-06-04 2003-12-04 Stanford, Office Of Technology Licensing Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US20040215102A1 (en) * 2001-08-09 2004-10-28 Susumu Ikehara Marrow fluid sampling set and marrow needle
FR2861572A1 (en) * 2003-10-30 2005-05-06 Patrice Richard DEVICE FOR TAKING AND / OR INJECTING BONE MARROW AND SYSTEM COMPRISING SUCH A DEVICE
US20060106363A1 (en) * 2004-07-01 2006-05-18 Aravena Ines M Injection systems
US20060211953A1 (en) * 2004-10-29 2006-09-21 Zannis Anthony D Coordinate instrument set
US20070270712A1 (en) * 2004-10-04 2007-11-22 Vibratech Ab Arrangement for Taking a Sample of Bone Marrow and/or Evacuating the Sinuses
US20070276352A1 (en) * 2002-06-04 2007-11-29 Stemcor Systems, Inc. Removable device and method for tissue disruption
WO2008002961A2 (en) * 2006-06-29 2008-01-03 Vidacare Corporation Apparatus and methods to harvest bone and bone marrow
US20080039884A1 (en) * 2006-08-10 2008-02-14 Nohilly Martin J Morcellator with detachable handle
US20080045861A1 (en) * 2002-05-31 2008-02-21 Miller Larry J Medical Procedures Trays And Related Methods
WO2008033872A2 (en) 2006-09-12 2008-03-20 Vidacare Corporation Biopsy devices and related methods
US20080109007A1 (en) * 2006-11-02 2008-05-08 Stryker Trauma Gmbh Implantation device, applicator and sonotrode
US20090149774A1 (en) * 2007-12-06 2009-06-11 Ebi, L.P. bone marrow aspiration needle
US7670328B2 (en) 2002-05-31 2010-03-02 Vidacare Corporation Apparatus and method to provide emergency access to bone marrow
US7811260B2 (en) 2002-05-31 2010-10-12 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US7815642B2 (en) 2004-01-26 2010-10-19 Vidacare Corporation Impact-driven intraosseous needle
US7850620B2 (en) 2002-05-31 2010-12-14 Vidacare Corporation Biopsy devices and related methods
US20110082387A1 (en) * 2002-05-31 2011-04-07 Miller Larry J Biopsy Devices and Related Methods
US20110082425A1 (en) * 2009-10-02 2011-04-07 Howmedica Osteonics Corp. Bone Marrow Aspirator And Methods Therefor
US20110184312A1 (en) * 2008-08-14 2011-07-28 Moran Jr Antonio Bone Tissue Extracting Device and Method
US7998086B2 (en) 2003-09-11 2011-08-16 Depuy Mitek, Inc. Tissue extraction and maceration device
US20110218502A1 (en) * 2008-11-14 2011-09-08 Toshiaki Iio Carrying case and syringe system with same
US8034003B2 (en) 2003-09-11 2011-10-11 Depuy Mitek, Inc. Tissue extraction and collection device
US20110264129A1 (en) * 2010-03-31 2011-10-27 James Alistair Holdgate Surgical instrument
WO2012007812A1 (en) * 2010-07-15 2012-01-19 Kebomed Ag Laparoscopic morcellator
US8142365B2 (en) 2002-05-31 2012-03-27 Vidacare Corporation Apparatus and method for accessing the bone marrow of the sternum
EP2438867A3 (en) * 2010-10-05 2012-05-02 Trokamed GmbH Medical instrument
US8419683B2 (en) 2004-11-12 2013-04-16 Vidacare Corporation Intraosseous device and methods for accessing bone marrow in the sternum and other target areas
US8562542B2 (en) 2003-03-28 2013-10-22 Depuy Mitek, Llc Tissue collection device and methods
US20140031794A1 (en) * 2011-04-19 2014-01-30 Ao Technology Ag Cannula and kit for evaluation and preparation of bone tissue
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
US8690791B2 (en) 2002-05-31 2014-04-08 Vidacare Corporation Apparatus and method to access the bone marrow
US20140144663A1 (en) * 2012-11-28 2014-05-29 Robert Bosch Gmbh Portable power tool
US20150032067A1 (en) * 2013-03-12 2015-01-29 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
US8974410B2 (en) 2006-10-30 2015-03-10 Vidacare LLC Apparatus and methods to communicate fluids and/or support intraosseous devices
US9072543B2 (en) 2002-05-31 2015-07-07 Vidacare LLC Vascular access kits and methods
US9173679B2 (en) 2011-04-11 2015-11-03 Waismed Ltd. Intraosseous device for inserting a cannula into a bone
US9314228B2 (en) 2002-05-31 2016-04-19 Vidacare LLC Apparatus and method for accessing the bone marrow
US9433400B2 (en) 2004-01-26 2016-09-06 Vidacare LLC Manual intraosseous device
US9439667B2 (en) 2002-05-31 2016-09-13 Vidacare LLC Apparatus and methods to install, support and/or monitor performance of intraosseous devices
US9451968B2 (en) 2002-05-31 2016-09-27 Vidacare LLC Powered drivers, intraosseous devices and methods to access bone marrow
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
US9730729B2 (en) 2011-07-11 2017-08-15 Teleflex Medical Devices S.A R.L. Sternal locators and associated systems and methods
US9770425B2 (en) 2014-10-09 2017-09-26 Aperture Medical Technology Llc Implantable bone marrow access apparatus
US9839740B2 (en) 2010-02-02 2017-12-12 Teleflex Medical Devices S.À R.L Intraosseous-needle stabilizer and methods
WO2018006045A1 (en) * 2016-06-30 2018-01-04 Actuated Medical, Inc. Medical device for delivery and/or extraction of material
CN107595327A (en) * 2017-10-20 2018-01-19 中国人民解放军第四军医大学 Parathyroid gland accurately identifies method and its detection means in art
US20180028212A1 (en) * 2016-07-28 2018-02-01 Covidien Lp Reciprocating rotary surgical cutting device and system for tissue resecting, and method for its use
US20180085115A1 (en) * 2006-01-27 2018-03-29 Endoevolution, Llc Apparatus and method for tissue closure
US20180092632A1 (en) * 2016-10-05 2018-04-05 Aperture Medical Technology Llc Bone marrow access apparatus
US20180140319A1 (en) * 2016-11-23 2018-05-24 Iyad Saidi Apparatus and methods for tissue reduction
CN108309364A (en) * 2018-02-06 2018-07-24 重庆医科大学附属永川医院 A kind of marrow puncture device and its piercing method
US10052109B2 (en) 2012-07-12 2018-08-21 DePuy Synthes Products, Inc. Saw, a saw blade, a connection mechanism and associated methods
WO2018165334A1 (en) * 2017-03-07 2018-09-13 Piper Access, Llc. Safety shields for elongated instruments and related systems and methods
CN108836444A (en) * 2018-05-08 2018-11-20 徐州蓝湖信息科技有限公司 A kind of clinical medicine stem cell extraction puncturing structure
US10136878B2 (en) 2015-12-24 2018-11-27 Waismed Ltd. Automatic device and kit for inserting a cannula to a predetermined depth within a bone, irrespective of the thickness of the tissue above the bone
WO2019051343A1 (en) * 2017-09-09 2019-03-14 June Medical Ip, Llc Passive safety intraosseous device
WO2019173411A1 (en) * 2018-03-05 2019-09-12 Piper Access, Llc Bone biopsy devices, systems, and methods
US10576594B2 (en) * 2017-03-29 2020-03-03 Michael Paul Hill Center point drill and center point drill attachment
US10653444B2 (en) 2013-07-01 2020-05-19 Merit Medical Systems, Inc. Perforating trocar
US20200229932A1 (en) * 2016-05-26 2020-07-23 Dmitry Arbuck Methods and tools for treating bone pain
CN111954484A (en) * 2018-04-11 2020-11-17 波士顿科学国际有限公司 Apparatus and method for extending a working channel
WO2020264463A1 (en) * 2019-06-28 2020-12-30 H & M Innovations, Llc Harvesting cancellous bone and bone marrow using bone press apparatus
CN112245671A (en) * 2020-11-02 2021-01-22 王天琦 Gall bladder puncture drainage check out test set
US10898218B2 (en) 2019-02-25 2021-01-26 Covidien Lp Tissue resecting device including a motor cooling assembly
WO2021062394A1 (en) * 2019-09-27 2021-04-01 Bard Access Systems, Inc. Various operating mechanisms for intraosseous access medical devices and methods thereof
US10973532B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US11013901B2 (en) 2017-03-10 2021-05-25 Piper Access, Llc Securement devices, systems, and methods
US20210259803A1 (en) * 2020-02-25 2021-08-26 Amit R. Patel Drill for surgical screw insertion with reoriented torque
CN113317849A (en) * 2021-04-22 2021-08-31 卫飞 Bone puncture needle emitter
CN113575570A (en) * 2021-09-01 2021-11-02 河南中博科技有限公司 Method for manufacturing plasticized specimen not easy to mildew
US11191550B2 (en) 2018-02-20 2021-12-07 Piper Access, Llc Medical drilling devices and related systems and methods
US11298202B2 (en) 2002-05-31 2022-04-12 Teleflex Life Sciences Limited Biopsy devices and related methods
US11337728B2 (en) 2002-05-31 2022-05-24 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US11344319B2 (en) 2019-06-28 2022-05-31 H & M Innovations, Llc Harvesting cancellous bone and marrow from intramedullary canal formed in medullary cavity using bone press apparatus
US11357515B2 (en) 2017-09-09 2022-06-14 June Access Ip, Llc Intraosseous device having retractable motor/stylet assembly and automatic stylet point cover upon retraction operation
US11389141B2 (en) 2016-02-01 2022-07-19 RegenMed Systems, Inc. Cannula for tissue disruption
US11517349B2 (en) 2019-09-27 2022-12-06 Bard Access Systems, Inc. Autovance feature of an intraosseous device
US11534145B2 (en) 2018-10-12 2022-12-27 Aperture Medical Technology Llc Bone marrow access apparatus and methods for locating same
US11583442B2 (en) 2017-04-09 2023-02-21 Sanoculis Ltd. Device and method for creating a channel in soft tissue
US20230181176A1 (en) * 2011-01-28 2023-06-15 The General Hospital Corporation Apparatus and method for tissue biopsy
US11759235B2 (en) 2019-09-27 2023-09-19 Bard Access Systems, Inc. Constant-torque intraosseous access devices and methods thereof
US11883071B2 (en) 2016-10-27 2024-01-30 C. R. Bard, Inc. Intraosseous access device
US11896264B2 (en) 2020-04-21 2024-02-13 Bard Access Systems, Inc. Reusable push-activated intraosseous access device
US11925361B2 (en) 2022-02-08 2024-03-12 Bard Access Systems, Inc. Intraosseous modular power

Families Citing this family (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6912927B2 (en) * 2002-05-15 2005-07-05 Reliance Electric Technologies, Llc Modular-flexible wormshaft assembly
DE60326014D1 (en) * 2003-04-04 2009-03-12 Laura Raus osteotome
US7641620B2 (en) * 2003-12-23 2010-01-05 Vance Products Incorporated Rotatable sampling apparatus
JP4542362B2 (en) * 2004-04-15 2010-09-15 オリンパス株式会社 Endoscopic treatment system
US7740594B2 (en) * 2004-09-29 2010-06-22 Ethicon Endo-Surgery, Inc. Cutter for biopsy device
DE102004049247A1 (en) 2004-10-01 2006-04-13 Aesculap Ag & Co. Kg Surgical instrument
DE102004049243B4 (en) * 2004-10-01 2008-07-10 Fabrizio Dr. Caroli Surgical instrument
JP2008515480A (en) * 2004-10-04 2008-05-15 ビブラテック・アクチボラゲット Device for taking bone marrow samples and / or for eliminating cavities
US7749194B2 (en) 2005-02-01 2010-07-06 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US8172886B2 (en) 2004-12-14 2012-05-08 Depuy Products, Inc. Bone plate with pre-assembled drill guide tips
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
DE102005005007B3 (en) * 2005-02-03 2006-09-07 Lts Lohmann Therapie-Systeme Ag Biopsy needle for histological examination of body tissue
CA2609970C (en) 2005-06-03 2014-08-12 Tyco Healthcare Group Lp Battery powered surgical instrument
BRMU8600004Y1 (en) * 2006-01-03 2014-12-09 Eugenio Machado De Andrade PROVISION INTRODUCED IN BIOPSY AND SIMILAR SAMPLE COLLECTOR
US7935126B2 (en) 2006-03-20 2011-05-03 Depuy Products, Inc. Bone plate shaping system
WO2007127102A2 (en) * 2006-04-28 2007-11-08 Harvest Technologies Corporation Injection of anticoagulant into bone marrow space
US20070282447A1 (en) * 2006-06-01 2007-12-06 Yedlicka Joseph W Fluid-transfer device, vertebral treatment device,system and methods of use
WO2008010992A1 (en) * 2006-07-17 2008-01-24 Abeo, Llc Motor having a hollow drive shaft
CA2662958C (en) 2006-09-13 2015-01-13 Vascular Insights Llc Vascular treatment device
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
JP4576587B2 (en) 2007-01-23 2010-11-10 株式会社Jimro Bone marrow drill
US8696674B2 (en) 2007-03-30 2014-04-15 Smith & Nephew, Inc. Tissue harvesting
CN101541253B (en) * 2007-04-04 2014-04-23 维达保健公司 Electric driving device
US7833204B2 (en) * 2007-05-14 2010-11-16 Applied Medical Research Intramedullary access or infusion devices
CN101720243A (en) * 2007-05-17 2010-06-02 维达保健公司 Monitor patients and with the method and apparatus of treat with intraosseous fluids
WO2008144552A1 (en) * 2007-05-17 2008-11-27 Pro-Dex, Inc. Handheld medical device
JP5325101B2 (en) * 2007-06-11 2013-10-23 株式会社根本杏林堂 Nozzle adapter for chemical syringe
EP2022522B1 (en) * 2007-07-25 2011-12-28 W & H Dentalwerk Bürmoos GmbH Devices and methods for the injection of agents into human and animal tissue
JP5570971B2 (en) * 2007-08-08 2014-08-13 スミス アンド ネフュー インコーポレーテッド Tissue collection
CA2698200C (en) 2007-09-04 2015-03-24 Strathmore Industries Inc. Method and apparatus for aspiration
SG154343A1 (en) * 2008-01-08 2009-08-28 Ting Choon Meng Method and apparatus for intra-articular injection or aspiration
US8388621B2 (en) 2008-03-06 2013-03-05 Smith & Nephew, Inc. Retrodrill system
US8494608B2 (en) * 2008-04-18 2013-07-23 Medtronic, Inc. Method and apparatus for mapping a structure
US9011412B2 (en) 2008-05-16 2015-04-21 Ford Albritton, IV Apparatus, system and method for manipulating a surgical catheter and working device with a single hand
JP5350474B2 (en) 2008-06-26 2013-11-27 ウェイン・アンダーソン Medical driver device whose depth is controllable and measurable and method of using the same
US8114053B2 (en) * 2008-07-17 2012-02-14 Tyco Healthcare Group Lp Port fixation with interlocking structure
US7850651B2 (en) * 2008-09-15 2010-12-14 Biomet Biologics, Llc Bone marrow aspiration needle
US8273053B2 (en) * 2009-05-05 2012-09-25 Pyng Medical Corp. Patient status sensor
WO2010138538A1 (en) 2009-05-26 2010-12-02 Zimmer, Inc. Handheld tool for driving a bone pin into a fractured bone
CN101934105B (en) * 2009-06-30 2013-03-20 王立祥 Disposable intra-bone marrow injection device
CN101601882B (en) * 2009-07-15 2012-02-01 无锡市宇寿医疗器械股份有限公司 Disposable safety syringe with replaceable and automatically retracted needle
CN101987220B (en) * 2009-07-30 2013-11-13 德昌电机(深圳)有限公司 Needle driving assembly for medical instrument
US8377013B2 (en) * 2009-08-05 2013-02-19 The University Of Toledo Needle for directional control of the injection of bone cement into a vertebral compression fracture
US8283890B2 (en) * 2009-09-25 2012-10-09 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
EP3763303A1 (en) 2009-10-01 2021-01-13 MAKO Surgical Corp. Surgical system for positioning prosthetic component and/or for constraining movement of surgical tool
EP2490603A1 (en) * 2009-10-20 2012-08-29 Smith & Nephew, Inc. Connector assembly
US8900181B2 (en) 2009-12-18 2014-12-02 Srgi Holdings, Llc Skin treatment and drug delivery device
JP5858930B2 (en) 2010-01-11 2016-02-10 プロ−デツクス・インコーポレイテツド Handheld medical device with thermal pad
WO2011123703A1 (en) * 2010-03-31 2011-10-06 Smart Medical Devices, Inc. Depth controllable and measurable medical driver devices
JP5833639B2 (en) * 2010-05-07 2015-12-16 ザ ジェネラル ホスピタル コーポレイション System for tissue transplantation and replication
US8986331B2 (en) * 2010-05-12 2015-03-24 Ethicon Endo-Surgery, Inc. Instrument for debriding fistula and applying therapeutic cells
US8858546B2 (en) 2010-05-12 2014-10-14 Ethicon Endo-Surgery, Inc. Instrument for debriding fistula and applying therapeutic cells
CN101926670B (en) * 2010-09-30 2013-05-08 重庆润泽医疗器械有限公司 Craniotomy drill
US20120116265A1 (en) 2010-11-05 2012-05-10 Houser Kevin L Surgical instrument with charging devices
US20120116381A1 (en) 2010-11-05 2012-05-10 Houser Kevin L Surgical instrument with charging station and wireless communication
US10660695B2 (en) 2010-11-05 2020-05-26 Ethicon Llc Sterile medical instrument charging device
US9585667B2 (en) 2010-11-15 2017-03-07 Vascular Insights Llc Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein
US9320535B2 (en) * 2010-11-15 2016-04-26 Spine View, Inc. Tissue removal system with retention mechanism
US11000310B2 (en) 2010-12-17 2021-05-11 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US10702684B2 (en) 2010-12-17 2020-07-07 Srgi Holdings, Llc Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal
US10736653B2 (en) 2013-12-06 2020-08-11 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11278309B2 (en) 2010-12-17 2022-03-22 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11103275B2 (en) 2010-12-17 2021-08-31 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11109887B2 (en) * 2013-12-06 2021-09-07 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US10716924B2 (en) 2010-12-17 2020-07-21 Srgi Holdings, Llc Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal
US10695546B2 (en) 2010-12-17 2020-06-30 Srgi Holdings, Llc Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal
US9101441B2 (en) 2010-12-21 2015-08-11 Alcon Research, Ltd. Vitrectomy probe with adjustable cutter port size
US8888802B2 (en) 2010-12-21 2014-11-18 Alcon Research, Ltd. Vitrectomy probe with adjustable cutter port size
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9943360B2 (en) 2011-01-30 2018-04-17 University Health Network Coil electrode for thermal therapy
CN102225021B (en) * 2011-05-26 2013-05-01 王玉梅 Bone marrow puncture device for children
EP2726006A1 (en) * 2011-06-28 2014-05-07 SafeAir AG An elongated electrosurgical instrument, a suction tip for the electrosurgical instrument and method of adjusting the axial position of the suction tip on the electrosurgical instrument
BE1020047A3 (en) * 2011-07-05 2013-04-02 Janssens Johan INSTRUMENT TO TAKE A BOTBIOPSY.
US20130041385A1 (en) * 2011-08-10 2013-02-14 Joseph Giovannoli Apparatus for skin reduction
US20130150752A1 (en) * 2011-12-12 2013-06-13 Karl W. Swann Apparatus for Bone Aspiration
US9095409B2 (en) * 2011-12-20 2015-08-04 Alcon Research, Ltd. Vitrectomy probe with adjustable cutter port size
US8894647B2 (en) * 2012-01-13 2014-11-25 Covidien Lp System and method for performing surgical procedures with a reusable instrument module
JP5974616B2 (en) * 2012-04-30 2016-08-23 日立工機株式会社 Electric tool
WO2014011841A1 (en) 2012-07-11 2014-01-16 Zimmer, Inc. Bone fixation tool
US9872687B2 (en) * 2012-07-19 2018-01-23 Clariance Driving assembly for a cutting tool of the shaver type
US9347533B2 (en) 2012-07-25 2016-05-24 Cook Medical Technologies Llc Rotational drive system for a biopsy member
US20140031715A1 (en) * 2012-07-30 2014-01-30 Michael David SHERAR Coil electrode apparatus for thermal therapy for treating bone tissue
EP2892607B1 (en) 2012-09-06 2019-08-07 Corindus, Inc System for guide catheter control
US9301735B2 (en) 2012-12-19 2016-04-05 Cook Medical Technologies Llc Drive system for a biopsy member
CA2896746A1 (en) 2012-12-27 2014-07-03 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
EP2961447A4 (en) * 2013-03-01 2016-11-09 Us Health Direct pressure-mediated intra-bone delivery system for cellular therapeutics
US9308020B2 (en) 2013-03-14 2016-04-12 Cook Medical Technologies Llc Tri-fluted vascular access needle
AU2013381963B2 (en) 2013-03-15 2017-04-13 Teleflex Medical Devices S.À R.L. Intraosseous device handles, systems, and methods
US20140262880A1 (en) * 2013-03-15 2014-09-18 Vidacare Corporation Containment Assemblies, Methods, and Kits
US9615816B2 (en) 2013-03-15 2017-04-11 Vidacare LLC Drivers and drive systems
KR101466747B1 (en) * 2013-09-27 2014-11-28 주의탁 Drilling Device For Acromioplasty
MX2016004331A (en) 2013-10-02 2016-11-10 Srgi Holdings Llc Pixel array medical devices and methods.
ES2827049T3 (en) 2013-10-02 2021-05-19 Srgi Holdings Llc Pixel Set Medical Devices
US9445941B2 (en) * 2013-11-07 2016-09-20 Drug Delivery Company, Llc Bioresorbable drug eluting intravitreal implant system and method
CN103750879B (en) * 2013-11-28 2015-09-02 张秀华 A kind of brill cranium device of neurosurgery
US11229452B2 (en) 2013-12-06 2022-01-25 Srgi Holdings, Llc Pixel array medical systems, devices and methods
WO2015109100A1 (en) * 2014-01-15 2015-07-23 Endocellutions, Inc. Bone marrow harvesting needle improvements
CN110200663B (en) * 2014-02-17 2022-04-29 泰利福生命科学有限公司 Power driver actuated by force on a drive shaft and related kits, components, and methods
CA2944654C (en) 2014-04-03 2020-07-14 Zimmer, Inc. Orthopedic tool for bone fixation
US10631888B2 (en) * 2014-04-28 2020-04-28 Emory University Systems and methods for tissue treatment
US9925068B2 (en) 2014-05-30 2018-03-27 Treace Medical Concepts, Inc. Bone harvester and bone marrow removal system and method
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US10335126B2 (en) 2014-07-30 2019-07-02 Arthrex, Inc. Bone marrow aspiration needle assembly
CN105555209A (en) * 2014-08-19 2016-05-04 瑞特医疗技术公司 Geared instrument for tibial stem reaming or removal
EP3579767A4 (en) 2014-10-02 2020-11-18 SRGI Holdings, LLC Pixel array medical systems, devices and methods
US10426940B2 (en) 2014-11-13 2019-10-01 PAVmed Inc. Intraosseous infusion ports and methods of use
US10898196B2 (en) * 2014-11-21 2021-01-26 Covidien Lp Cleaning apparatus for surgical instruments
CN104510505B (en) * 2015-01-12 2016-11-16 周健 Vertebral body sampling trepan
CN105852914B (en) * 2015-01-12 2018-09-14 青岛亿嘉诺日化有限公司 Medical orthopedic samples trepan
CN104644272A (en) * 2015-01-23 2015-05-27 芜湖锐进医疗设备有限公司 Medical electric saw storage box
WO2016125032A1 (en) * 2015-02-02 2016-08-11 Yale University Integrated painless bone marrow biopsy device
EP3253308A4 (en) 2015-02-05 2018-10-24 SRGI Holdings LLC Pixel array medical systems, devices and methods
RU2594980C1 (en) * 2015-03-03 2016-08-20 Константин Сергеевич Казанин Device to puncture proximal end of femur
CN104799956A (en) * 2015-04-10 2015-07-29 芜湖锐进医疗设备有限公司 Storing plate of drill bit and swing saw
US10299804B2 (en) * 2015-05-31 2019-05-28 Insurgical, Inc. Dual speed medical procedure power tool
US11759231B2 (en) 2015-08-31 2023-09-19 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11490952B2 (en) 2015-08-31 2022-11-08 Srgi Holdings, Llc Pixel array medical devices and methods
EP3808287B1 (en) 2015-09-03 2023-08-16 Stryker Corporation Powered surgical drill with integral depth gauge that includes a probe that slides over the drill bit
DE202015105693U1 (en) * 2015-10-26 2017-01-27 Autefa Solutions Germany Gmbh Entnadelungswerkzeug
US10631880B1 (en) * 2015-12-01 2020-04-28 Innovative Medical Solutions LLC Cannulated modular magnetic glenoid reamer
CN105455857B (en) * 2016-01-14 2018-05-04 黄泽浩 A kind of medullo-puncture needle aids in sting device
US20170203053A1 (en) * 2016-01-19 2017-07-20 Joseph Choate Burkett Visual-Assisted Insertion Device
US11564706B2 (en) 2019-10-28 2023-01-31 Srgi Holdings, Llc Pixel array medical systems, devices and methods
EP3413812B1 (en) 2016-02-12 2021-05-19 Smart Medical Devices, Inc. Driving devices for determining material strength in real-time
EP3422986B1 (en) 2016-03-04 2023-12-27 Covidien LP Robotic surgical assemblies
CN106308853A (en) * 2016-08-17 2017-01-11 中国人民解放军第三军医大学第二附属医院 Bone marrow aspiration needle of hematology department
JP7091350B2 (en) * 2016-10-18 2022-06-27 パイパー・アクセス、エルエルシー Intraosseous access devices, systems, and methods
US10966704B2 (en) 2016-11-09 2021-04-06 Biomet Sports Medicine, Llc Methods and systems for stitching soft tissue to bone
CA3046354A1 (en) 2017-01-17 2018-07-26 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
US10874406B2 (en) * 2017-02-28 2020-12-29 MFr Technologies, Inc. Handheld surgical instrument
WO2018160269A1 (en) * 2017-03-03 2018-09-07 The Johns Hopkins University Steerable device for treatment of hard-tissue-related diseases and minimally invasive surgery
US11406364B2 (en) * 2017-03-08 2022-08-09 Access Health, Llc Selectively extendable and retractable biopsy devices
CN107583127B (en) * 2017-08-31 2020-07-28 安徽信息工程学院 Transfusion system
EP3681420B1 (en) 2017-09-11 2023-08-16 Teleflex Life Sciences Limited Powered intraosseous driver with protective member, and related kits and components
US10959755B2 (en) 2017-11-02 2021-03-30 Shippert Tech, Llc Apparatus and method for removing intra-osseous device
DE202017106855U1 (en) * 2017-11-10 2018-01-12 Olaf Thiessies Lavage system
RU177286U1 (en) * 2017-12-04 2018-02-15 Федеральное государственное бюджетное образовательное учреждение высшего образования Санкт-Петербургская государственная академия ветеринарной медицины Puncture needle for obtaining bone marrow punctate in cattle
WO2019125428A1 (en) 2017-12-20 2019-06-27 C. R. Bard, Inc. Biopsy device having a linear motor
WO2019125699A1 (en) * 2017-12-21 2019-06-27 Tact Ip, Llc Auto-injector devices to facilitate perispinal delivery of biologics and drugs
US11304709B2 (en) 2018-01-25 2022-04-19 Medtronic Holdings Company Sarl Adaptor and drill for use with a driver and a cannula for drilling into bone
US10980587B2 (en) 2018-01-25 2021-04-20 Medtronic Holding Company Sàrl Adaptor for use with a driver, a drill, and a cannula for drilling into bone
USD893709S1 (en) * 2018-02-02 2020-08-18 Ferton Holding S.A. Medical device
WO2019195221A1 (en) * 2018-04-06 2019-10-10 Tendonova Corporation Improved devices for tissue treatment and methods of use thereof
WO2019236042A2 (en) * 2018-06-07 2019-12-12 Matek Medikal Aygitlar Teknoloji Sanayi Ve Ticaret Anonim Sirketi Intraosseous infusion device
CN109124694B (en) * 2018-08-14 2021-08-27 温州市中心医院 Bone marrow puncture needle for hematology department
EP3886739A1 (en) * 2018-11-28 2021-10-06 Teleflex Medical Devices S.à.r.l. Pull chord manually driven intraosseous injection devices and methods
WO2020113144A1 (en) 2018-11-29 2020-06-04 Hubly Inc. System and method for integrated surgical guide-hub and drill with guided drilling and plunge protection
WO2020141408A1 (en) * 2019-01-04 2020-07-09 Teleflex Medical Devices S.A.R.L. Hand crank manually driven intraosseous injection devices and methods
US11123086B1 (en) * 2019-01-04 2021-09-21 Innovative Medical Solutions LLC Cannulated modular magnetic glenoid reamer
CN109875638B (en) * 2019-03-06 2021-08-10 何志友 Medical intramedullary vein reflux device
CN109893177B (en) * 2019-04-24 2021-05-04 山东省立医院 Marrow puncture extraction device
US11344309B2 (en) * 2019-07-05 2022-05-31 Covidien Lp Circular stapling instruments
CN110522498A (en) * 2019-08-27 2019-12-03 重庆医科大学附属第一医院 A kind of full-automatic bone marrow aspiration infusion device of hand-held
CN110859660B (en) * 2019-11-26 2020-12-29 潘宝军 Thyroid cyst puncture suction device
CN215606058U (en) * 2020-06-03 2022-01-25 巴德阿克塞斯系统股份有限公司 Obturator assembly configured for use with an intraosseous access system
USD968627S1 (en) * 2020-08-07 2022-11-01 Recensmedical, Inc. Medical cooling device
USD968626S1 (en) * 2020-08-07 2022-11-01 Recensmedical, Inc. Medical cooling device
WO2022056005A1 (en) * 2020-09-09 2022-03-17 Bard Access Systems, Inc. Aspiration apparatus for intraosseous access system
US20220133334A1 (en) * 2020-11-05 2022-05-05 Warsaw Orthopedic, Inc. Protected drill
CN112370126A (en) * 2020-11-27 2021-02-19 山西白求恩医院(山西医学科学院) Self-negative pressure pericardium puncture device
USD974558S1 (en) 2020-12-18 2023-01-03 Stryker European Operations Limited Ultrasonic knife
US11696793B2 (en) 2021-03-19 2023-07-11 Crossfire Medical Inc Vascular ablation
US11369789B2 (en) 2021-04-05 2022-06-28 Ishaan Jain Transdermal drug delivery system
CN113331923B (en) * 2021-04-21 2022-11-11 四川大学华西医院 Bone channel infusion device
WO2023137375A1 (en) * 2022-01-12 2023-07-20 Innovative Drive Corporation Mechanical hole punch for the reduction of intraocular pressure and methods of use
US20230285049A1 (en) * 2022-03-14 2023-09-14 Bard Access Systems, Inc. Intraosseous Access System
US11911581B1 (en) 2022-11-04 2024-02-27 Controlled Delivery Systems, Inc. Catheters and related methods for the aspiration controlled delivery of closure agents

Citations (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US389445A (en) * 1888-09-11 William crede
US2317648A (en) * 1941-07-08 1943-04-27 Ivar E Siqveland Process and apparatus for producing intraosseous anesthesia
US2419045A (en) * 1947-01-04 1947-04-15 Charles C Whittaker Spring-driven rotatable surgical cutter with hand pressure speed control
US2773501A (en) * 1955-01-26 1956-12-11 Harold S Young Drill element for effecting intraosseous fluid injections and the like
US3120845A (en) * 1961-02-20 1964-02-11 David B Horner Self-powered surgical drill
US3173417A (en) * 1961-06-15 1965-03-16 David B Horner Self-powered sterilizable surgical drill
US3893445A (en) * 1974-01-09 1975-07-08 Becton Dickinson Co Bone marrow biopsy instrument
US4258722A (en) * 1978-12-15 1981-03-31 Ferris Manufacturing Corp. Disposable biopsy needle, particularly for bone marrow samplings
US4262676A (en) * 1979-08-24 1981-04-21 Khosrow Jamshidi Biopsy needle having integral stylet locking device
US4381777A (en) * 1980-01-14 1983-05-03 Micro-Mega S.A. Syringe with oscillating needle
US4469109A (en) * 1981-12-24 1984-09-04 Creative Research And Manufacturing Inc. Bone marrow aspiration needle
US4655226A (en) * 1983-12-16 1987-04-07 Southland Instruments, Inc. Disposable biopsy needle unit
US4692073A (en) * 1985-02-25 1987-09-08 Martindell J Richard Handle adapter and chuck apparatus for power bits
US4723945A (en) * 1984-05-03 1988-02-09 Bunder Glas Gmbh Hypodermic syringe
US4787893A (en) * 1985-05-09 1988-11-29 Alain Villette Instrument for injecting biocompatible products through bone tissue
US4867158A (en) * 1987-07-20 1989-09-19 Sugg Winfred L Hand held battery powered bone awl
US4919146A (en) * 1988-10-25 1990-04-24 Medrad, Inc. Biopsy device
US4969870A (en) * 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
US5122114A (en) * 1991-02-01 1992-06-16 Board Of Regents, University Of Texas System Method of using intramedullary catheter
US5139500A (en) * 1989-05-08 1992-08-18 Schwartz Nathan H Bone attachment system
US5195985A (en) * 1990-05-25 1993-03-23 Hall John E Syringe having a retractable needle
US5207697A (en) * 1991-06-27 1993-05-04 Stryker Corporation Battery powered surgical handpiece
US5257632A (en) * 1992-09-09 1993-11-02 Symbiosis Corporation Coaxial bone marrow biopsy coring and aspirating needle assembly and method of use thereof
US5279306A (en) * 1981-03-16 1994-01-18 Creative Research And Manufacturing Biopsy needle
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
US5324300A (en) * 1991-10-25 1994-06-28 Elias Elias G Device for the controlled excision of tissue from a living body
US5332398A (en) * 1992-02-01 1994-07-26 Board Of Regents, The University Of Texas System Intramedullary catheter
US5423824A (en) * 1992-03-23 1995-06-13 Radi Medical Systems Ab Method of accessing hard tissue
US5431655A (en) * 1988-10-24 1995-07-11 Cook Incorporated Intraosseous needle
US5451210A (en) * 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
US5554154A (en) * 1995-03-03 1996-09-10 Rosenberg; Norman Intra-osseous needle drill
US5586847A (en) * 1995-06-06 1996-12-24 Mattern, Jr.; Charles J. Power tool adapter
US5591188A (en) * 1994-04-12 1997-01-07 Wais-Med Lmt, A Subsidiary Company Of Teic Technion Enterpreneurial Incubator Ltd. Surgical instrument for impact insertion of an intraosseous trocar-needle
US5762639A (en) * 1995-04-07 1998-06-09 Gibbs; David E. Device for targeted, catherized delivery of medications
US5779708A (en) * 1996-08-15 1998-07-14 Cyberdent, Inc. Intraosseous drug delivery device and method
US5817052A (en) * 1995-12-26 1998-10-06 Pyng Medical Corp. Apparatus for intraosseous infusion or aspiration
US5924864A (en) * 1997-04-18 1999-07-20 Kaltenbach & Voigt Gmbh Handpiece for medical purposes, in particular for a medical or dental treatment device, preferably for a cutting treatment of a dental root canal
US5928238A (en) * 1995-03-15 1999-07-27 Osteotech, Inc. Bone dowel cutter
US5927976A (en) * 1996-05-10 1999-07-27 Cyberdent, Inc. Medication injection device and method
US5941706A (en) * 1997-10-20 1999-08-24 Ura; Robert S. Variable depth medical drill and method of making the same
US5980545A (en) * 1996-05-13 1999-11-09 United States Surgical Corporation Coring device and method
US6033369A (en) * 1998-09-23 2000-03-07 Goldenberg; Alec Disposable handle and needle assembly
US6096042A (en) * 1996-01-04 2000-08-01 Herbert; Timothy James Driver
US6110129A (en) * 1998-07-13 2000-08-29 Medical Device Technologies, Inc. Biopsy needle and surgical instrument
US6135769A (en) * 1998-11-20 2000-10-24 Kwan; Danny Pak-Nam Intraosseous injection system
US6183442B1 (en) * 1998-03-02 2001-02-06 Board Of Regents Of The University Of Texas System Tissue penetrating device and methods for using same
US6210376B1 (en) * 1999-04-08 2001-04-03 New York University Cannulated delivery pin
US6217561B1 (en) * 1995-06-06 2001-04-17 David Gibbs Medication injection device and method
US6221029B1 (en) * 1999-05-13 2001-04-24 Stryker Corporation Universal biopsy system
US6247928B1 (en) * 1998-04-09 2001-06-19 Moshe Meller Disposable anesthesia delivery system
US6257351B1 (en) * 1999-06-29 2001-07-10 Microaire Surgical Instruments, Inc. Powered surgical instrument having locking systems and a clutch mechanism
US6273715B1 (en) * 1999-06-09 2001-08-14 X-Tip Technologies, Llc Disposable anesthesia delivery system with shortened outer sleeve and inner hollow drill
US6283970B1 (en) * 1997-03-20 2001-09-04 Philipp Lubinus Cutting tool for cleaning out the femur medullary space and artificial hip to be inserted into this space
US6287114B1 (en) * 1999-06-09 2001-09-11 X-Tip Technologies, Llc Disposable anesthesia delivery system with shortened outer sleeve and inner solid drill
US6302852B1 (en) * 2000-04-25 2001-10-16 Manan Medical Products, Inc. Bone marrow biopsy device
US6312394B1 (en) * 2000-04-25 2001-11-06 Manan Medical Products, Inc. Bone marrow biopsy device
US6315737B1 (en) * 1998-01-02 2001-11-13 Biopsy Needle Limited Partnership Biopsy needle for a biopsy instrument
US6325806B1 (en) * 1995-10-30 2001-12-04 Biomedical Enterprises, Inc. Materials collection system and uses thereof
US6328744B1 (en) * 1999-06-04 2001-12-11 American Medical Systems, Inc. Bone suturing device
US20020029007A1 (en) * 1997-09-19 2002-03-07 Bryan Graham W. Biopsy apparatus and method
US6358252B1 (en) * 1997-07-01 2002-03-19 Ira L. Shapira Apparatus for extracting bone marrow
US6468248B2 (en) * 1995-06-06 2002-10-22 David Gibbs Device for targeted, catherized delivery of medications
US6478751B1 (en) * 2000-04-18 2002-11-12 Allegiance Corporation Bone marrow aspiration needle
US20030009132A1 (en) * 2001-04-13 2003-01-09 Tricardia Llc Syringe system
US20030032939A1 (en) * 1995-06-06 2003-02-13 David Gibbs Device for targeted, catherized delivery of medications
US6523698B1 (en) * 1993-07-12 2003-02-25 Baxter International, Inc. Bone marrow kit
US6547561B2 (en) * 1999-06-09 2003-04-15 Tulsa Dental Products Inc. Disposable anesthesia delivery system with shortened outer sleeve and inner hollow drill
US20030078586A1 (en) * 1997-07-01 2003-04-24 Shapira Ira L. Method and apparatus for extracting bone marrow
US6582399B1 (en) * 1998-04-27 2003-06-24 Computer Controlled Syringe Inc. Syringe with detachable syringe barrel
US20030191414A1 (en) * 1999-10-19 2003-10-09 Kyphon Inc. Hand-held instruments that access interior body regions
US20030225411A1 (en) * 2002-05-31 2003-12-04 Vidacare Corporation Apparatus and method to access bone marrow
US6761726B1 (en) * 1998-05-15 2004-07-13 Pyng Medical Corp. Method and apparatus for the intraosseous introduction of a device such as an infusion tube
US6875219B2 (en) * 2003-02-14 2005-04-05 Yves P. Arramon Bone access system

Family Cites Families (657)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE24056E (en) 1955-08-30 Johansen
US679657A (en) * 1901-02-13 1901-07-30 Frank Williams Paper-rack.
US694669A (en) * 1901-07-17 1902-03-04 James T Sargent Washboard.
US1272104A (en) 1914-11-25 1918-07-09 Richard H Riethmueller Hypodermic needle.
US1539637A (en) 1923-06-04 1925-05-26 Finn J Bronner Dental instrument
US1686482A (en) 1927-05-25 1928-10-02 Randolph T Windle Trigger lock for firearms
US1954620A (en) 1932-04-25 1934-04-10 Edwin L Connell Clutch
US2080202A (en) 1935-05-27 1937-05-11 Wilkie M Drake Trigger protector
US2130845A (en) 1936-12-19 1938-09-20 Siemens Ag Electrode arrangement
US2138842A (en) 1937-03-27 1938-12-06 Mitchell N Drew Pole setting device
US2219605A (en) 1938-06-06 1940-10-29 Turkel Henry Device for performing a biopsy
US2318648A (en) 1939-01-30 1943-05-11 H A Douglas Mfg Co Connector
FR853349A (en) * 1939-04-22 1940-03-15 Improvements to devices for removing pieces of tissue from human or animal organs
US2261958A (en) 1940-12-03 1941-11-11 Lucien S Burri Article of jewelry
US2426535A (en) 1944-10-21 1947-08-26 Turkel Henry Infusion and biopsy needle
GB629824A (en) * 1945-12-20 1949-09-29 Henry Turkel Infusion and biopsy needle
US2525839A (en) 1946-01-31 1950-10-17 Birtman Electric Co Variable-speed electric drill
US2525588A (en) 1946-12-12 1950-10-10 Leroy F Cameron Illuminated electric drill and the like
CH269534A (en) 1948-01-02 1950-07-15 Sig Schweiz Industrieges Firearm with trigger and safety device for the same.
US2660635A (en) 1948-12-08 1953-11-24 Ite Circuit Breaker Ltd Air operated circuit breaker
US2714026A (en) 1954-08-03 1955-07-26 R C S Eugineering Corp Rotating tool connector
US2817648A (en) 1954-12-24 1957-12-24 Hercules Powder Co Ltd Process for inhibiting polymerization in free-radical reactions
US2766907A (en) 1955-03-15 1956-10-16 Robbins Instr Corp Pressure infusion apparatus
US2876369A (en) 1955-04-28 1959-03-03 Dormeyer Corp Portable power drill
US2860635A (en) 1957-03-20 1958-11-18 Edgar H Wilburn Sterilizable and sterilized hypodermic syringe assemblies
US3022596A (en) 1960-05-11 1962-02-27 Colbert H Cannon Safety device for trigger guard
US3104448A (en) 1961-09-21 1963-09-24 Morrow Mortician's body cavity injector
US3175554A (en) 1963-03-26 1965-03-30 Becton Dickinson Co Split biopsy needle
US3413498A (en) 1965-08-09 1968-11-26 Rockwell Mfg Co Electrically powered hand tool
US3269046A (en) 1965-08-11 1966-08-30 Central Specialties Company Trigger shield for firearms
US3519858A (en) 1967-03-13 1970-07-07 Stanley Works Portable electrical tool having permanent magnet field
US3507276A (en) 1968-08-28 1970-04-21 Murray B Burgess Jet injector
US3543966A (en) 1968-10-16 1970-12-01 Mattel Inc Mixing and dispensing device
US3529580A (en) 1968-10-23 1970-09-22 Foster Wheeler Corp Start-up system
US3598108A (en) 1969-02-28 1971-08-10 Khosrow Jamshidi Biopsy technique and biopsy device
US3802555A (en) 1969-06-03 1974-04-09 Abbott Lab Surgical instrument package and handling procedure
US3536943A (en) 1969-10-31 1970-10-27 Rockwell Mfg Co Electrically powered hand tool
US3664163A (en) 1970-02-24 1972-05-23 Master Lock Co Protective anchoring assemblage
US3697223A (en) 1970-07-14 1972-10-10 Medipak Corp Ltd Container for surgical instruments and appliances
US3671699A (en) 1970-11-19 1972-06-20 Lucerne Products Inc Power tool control
US4040462A (en) 1971-03-08 1977-08-09 William P. Green Fasteners having threads formed of essentially helical coil structures
US3843143A (en) 1971-04-23 1974-10-22 T Laxson Chuck adapter
US3815605A (en) 1971-05-19 1974-06-11 Philips Corp Device and holder therefor for inserting a hollow coupling member into bone marrow
US3893455A (en) 1971-07-16 1975-07-08 Aubrey D Mcnally Male retaining device
US3713417A (en) 1971-07-26 1973-01-30 M Shugart Air operated ultrasonic transducer
US3734207A (en) 1971-12-27 1973-05-22 M Fishbein Battery powered orthopedic cutting tool
US3750667A (en) 1972-01-31 1973-08-07 N Pshenichny Device for intraosseous injection of liquid substances
US3844291A (en) 1973-04-26 1974-10-29 G Moen Grip device
US4021920A (en) * 1973-06-18 1977-05-10 Horst Kirschner Drilling or milling apparatus for the working of live bone, particularly for dentistry
US3835860A (en) 1973-06-21 1974-09-17 H Garretson Surgical bone punch
US3850158A (en) 1973-07-09 1974-11-26 E Elias Bone biopsy instrument and method
JPS5048287U (en) 1973-08-28 1975-05-13
US4046254A (en) 1973-09-19 1977-09-06 Kramer Steven G Surgical trays
ZA745849B (en) 1974-09-13 1975-11-26 Pienaar H An aid in the management of clinical emergencies in medical and dental practices and other circumstances
US3999110A (en) 1975-02-06 1976-12-21 The Black And Decker Manufacturing Company Battery pack and latch
US3991765A (en) 1975-04-09 1976-11-16 Howard Cohen Cricothyrotomy apparatus
US3976066A (en) 1975-04-28 1976-08-24 Mccartney James S Skin protective device
US4189266A (en) 1975-08-01 1980-02-19 George Koslow Rotary drill bit for hand-held power drills
CA1060744A (en) 1975-09-05 1979-08-21 Vernon H. Troutner Wire inserter and sterile wire pack
US4185619A (en) * 1975-12-01 1980-01-29 Atomic Products Corporation Retractable shield for syringes
US4359052A (en) 1976-01-26 1982-11-16 Concept Inc. Removable tip cautery
US4099518A (en) 1976-05-10 1978-07-11 Baylis Shelby M Biopsy apparatus
DE2621383A1 (en) 1976-05-14 1977-12-01 Gardner Denver Gmbh METHOD OF PLACING IMPLANTS INTO BONE AND APPARATUS
US4142517A (en) * 1976-07-23 1979-03-06 Contreras Guerrero De Stavropo Apparatus for extracting bone marrow specimens
JPS6043134B2 (en) 1977-08-25 1985-09-26 信紘 佐藤 Device for measuring reflection characteristics of biological organs and tissues
US4269192A (en) 1977-12-02 1981-05-26 Olympus Optical Co., Ltd. Stabbing apparatus for diagnosis of living body
US4170993A (en) 1978-03-13 1979-10-16 Marcial Alvarez Sliding I.V. needle carrier assembly
US4154026A (en) 1978-03-15 1979-05-15 Palthe John W Abrading tool
US4194505A (en) * 1978-09-15 1980-03-25 Vac-O-Cast, Inc. Containerized hypodermic module
US4200111A (en) 1978-09-21 1980-04-29 Harris Arthur M Specimen removal instrument
US4262376A (en) * 1978-10-20 1981-04-21 Nevins Robert L Method and apparatus for manufacturing a solar energy collector
US4299230A (en) 1979-05-09 1981-11-10 Olympus Optical Co., Ltd. Stabbing apparatus for diagnosis of living body
US4356826A (en) 1979-05-09 1982-11-02 Olympus Optical Co., Ltd. Stabbing apparatus for diagnosis of living body
FR2457105A1 (en) 1979-05-22 1980-12-19 Villette Alain Penetrating compact materials with injection syringe - rotary needle, used esp. for anaesthesia in dentistry
US4399723A (en) 1979-07-11 1983-08-23 Gilles Marleau Compact combination tool set
US4266555A (en) 1979-11-09 1981-05-12 Khosrow Jamshidi Biopsy needle with stylet and cannula orientation
EP0029968A3 (en) 1979-11-30 1982-01-27 Black & Decker Inc. Tool holder
DE8006721U1 (en) 1980-03-12 1981-09-03 Becker, Michael, 5020 Frechen INJECTION DEVICE FOR INTRAMUSCULAR INJECTION OF A MEDICINE, IN PARTICULAR INSULIN
DE3163728D1 (en) 1980-04-08 1984-06-28 Greater Glasgow Health Board Dispensing device
US4393872A (en) 1980-05-27 1983-07-19 Eder Instrument Co., Inc. Aspirating surgical forceps
GB2079831B (en) 1980-07-14 1984-07-11 Hayes Derek Improvements in gripping or locating devices
US4330093A (en) 1980-08-08 1982-05-18 Western Electric Company, Inc. Thumb-controlled hand-held tool
US4306570A (en) 1980-08-20 1981-12-22 Matthews Larry S Counter rotating biopsy needle
US4373518A (en) 1980-09-26 1983-02-15 Zimmer, Inc. Method of drilling living bone
US4504267A (en) 1980-11-28 1985-03-12 Parmelee William H Apparatus for intravenous injection of liquids
US4316463A (en) 1981-01-26 1982-02-23 Vac-O-Cast, Inc. Corrosive protected hypodermic module
US4487209A (en) 1981-03-16 1984-12-11 Creative Research And Manufacturing Inc. Biopsy needle
US4922602A (en) 1981-03-16 1990-05-08 Creative Research And Manufacturing, Inc. Method of manufacturing a biopsy needle
US4334529A (en) 1981-04-14 1982-06-15 Caroline G. Wirth Wirth's sterile, disposable surgical drape
JPS57179838A (en) 1981-04-30 1982-11-05 Konishiroku Photo Ind Co Ltd Cartridge and its manufacture
GB2099703B (en) 1981-06-10 1985-01-23 Downs Surgical Ltd Biopsy needle
US4484577A (en) 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4595322A (en) 1981-08-10 1986-06-17 Burke Clement Spade drill bit
US4461305A (en) * 1981-09-04 1984-07-24 Cibley Leonard J Automated biopsy device
US4441563A (en) * 1981-11-02 1984-04-10 Black & Decker Inc. Tool collet and control means
FR2516386A1 (en) 1981-11-16 1983-05-20 Walther Roger Medical partic. dental anaesthetic syringe for penetrating bone etc. - has power driven rotary needle which revolves during insertion
US4420085A (en) 1982-01-15 1983-12-13 The Kendall Company Stand up organizer
JPS5982011U (en) * 1982-11-25 1984-06-02 株式会社吉田製作所 Drive control device for dental treatment instruments
GB2130890B (en) * 1982-11-30 1987-07-29 Downs Surgical Plc Aspiration needle
JPS59119808A (en) * 1982-12-27 1984-07-11 Toshiba Corp Transformer for vehicle
JPS59119808U (en) 1983-01-31 1984-08-13 株式会社吉田製作所 dental handpiece
SE434332B (en) 1983-03-23 1984-07-23 Jan Ingemar Neslund CELL SAMPLING DEVICE
US4620539A (en) 1983-07-11 1986-11-04 Andrews E Trent Pistol grip, bone drill
US4553539A (en) 1983-09-30 1985-11-19 Surgikos, Inc. Bilateral fenestrated drape
US4645492A (en) 1983-10-11 1987-02-24 Medical Engineering Corporation Catheter anchoring device
US4578064A (en) 1983-12-21 1986-03-25 Survival Technology Inc. Plural dosage automatic injector with improved safety
US4522302A (en) 1984-03-05 1985-06-11 Sterling Drug Inc. Pre-sterilized medical procedure kit packages
DE3413793A1 (en) * 1984-04-12 1985-10-24 Brown, Boveri & Cie Ag, 6800 Mannheim DRIVE FOR A SWITCH
US4753345A (en) 1984-06-14 1988-06-28 American Home Products Corporation Hypodermic syringe tray
US4630616A (en) * 1984-06-15 1986-12-23 Berkley And Company, Inc. Bone marrow needle
JPS6132663A (en) 1984-07-25 1986-02-15 Matsushita Electric Ind Co Ltd Picture signal processing device
JPS6130476U (en) 1984-07-27 1986-02-24 株式会社 新飯田製作所 double chainstitch sewing machine
US4659329A (en) * 1984-07-27 1987-04-21 The Kendall Company Liquid drainage system
GB8424436D0 (en) * 1984-09-27 1984-10-31 Pratt Int Ltd Burnerd Surgical appliance
US4646731A (en) * 1985-05-20 1987-03-03 Brower Arthur B Self adhesive suture and bandage
US4670008A (en) * 1985-07-01 1987-06-02 Albertini Beat High flux threaded needle
US4702261A (en) 1985-07-03 1987-10-27 Sherwood Medical Company Biopsy device and method
US4838877A (en) 1985-08-06 1989-06-13 Massau Bruce A Polymeric hypodermic device
US4801293A (en) 1985-10-09 1989-01-31 Anthony Jackson Apparatus and method for detecting probe penetration of human epidural space and injecting a therapeutic substance thereinto
US4623335A (en) 1985-10-09 1986-11-18 Anthony Jackson Apparatus and methods for detecting probe penetration of human internal target tissue having predetermined internal pressure
US4711636A (en) 1985-11-08 1987-12-08 Bierman Steven F Catheterization system
GB8527646D0 (en) 1985-11-08 1985-12-11 Cox J A Devices for sampling drainage
DE3539912A1 (en) 1985-11-11 1987-05-14 Hilti Ag TOOL HOLDER FOR DRILLING AND CHISEL TOOLS
US4654034A (en) 1986-02-03 1987-03-31 Masters Edwin J Safety needle cap
US4728876A (en) 1986-02-19 1988-03-01 Minnesota Mining And Manufacturing Company Orthopedic drive assembly
US4654030A (en) 1986-02-24 1987-03-31 Endotherapeutics Trocar
US4696308A (en) * 1986-04-09 1987-09-29 The Cleveland Clinic Foundation Core sampling apparatus
US4713061A (en) 1986-07-14 1987-12-15 Survival Technology, Inc. Cartridge with universal plastic hub
JPS6327805A (en) 1986-07-21 1988-02-05 Sumitomo Electric Ind Ltd Member for connecting optical fiber and connecting method using same
US4720881A (en) 1986-09-08 1988-01-26 Meyers William K Anesthesia accessories
US4793363A (en) * 1986-09-11 1988-12-27 Sherwood Medical Company Biopsy needle
US4736850A (en) 1986-10-17 1988-04-12 W. L. Gore & Associates, Inc. Endothelial cell harvesting kit
GB8627808D0 (en) 1986-11-20 1986-12-17 Cox J A Sampling liquids from human/animal body
US4772261A (en) 1987-01-29 1988-09-20 Board Of Regents, The University Of Texas System Intramedullary catheter
US5217478A (en) 1987-02-18 1993-06-08 Linvatec Corporation Arthroscopic surgical instrument drive system
US4838282A (en) 1987-02-26 1989-06-13 Manan Manufacturing Co., Inc. Bone biopsy needle assembly
US5002546A (en) * 1987-04-13 1991-03-26 Romano Jack W Curved bore drilling apparatus
US4944677A (en) 1987-06-29 1990-07-31 Raymond Joseph Alexandre Intraosseus dental anesthesia apparatus and method
US4762118A (en) 1987-07-28 1988-08-09 Welch Allyn, Inc. Self-adjusting steering mechanism for borescope, endoscope, or guide tube
ES2007667A6 (en) 1987-07-28 1989-07-01 Espejo Martinez Antonio A device for locating the epidural space.
DE8712926U1 (en) 1987-09-25 1987-11-05 B. Braun Melsungen Ag, 3508 Melsungen, De
US5529580A (en) 1987-10-30 1996-06-25 Olympus Optical Co., Ltd. Surgical resecting tool
US5064426A (en) 1987-12-11 1991-11-12 Huebsch Donald L Apparatus for removal of bone cement
US4844259A (en) 1987-12-22 1989-07-04 Osteotech, Inc. Medical and surgical procedure pack
US4874181A (en) 1988-05-31 1989-10-17 Hsu Shing Wang Coupling member for securing a drilling head to the rotatable rod of a pneumatic tool body
US5204670A (en) 1988-08-29 1993-04-20 B. I. Incorporated Adaptable electric monitoring and identification system
US4940459A (en) 1988-10-12 1990-07-10 Mallinckrodt, Inc. Inflation device for balloon catheter
US5601559A (en) * 1988-10-24 1997-02-11 Cook Incorporated Intraosseous needle
US5172700A (en) 1989-01-31 1992-12-22 C. R. Bard, Inc. Disposable biopsy forceps
US4986279A (en) * 1989-03-01 1991-01-22 National-Standard Company Localization needle assembly with reinforced needle assembly
US5025797A (en) 1989-03-29 1991-06-25 Baran Gregory W Automated biopsy instrument
US5400798A (en) * 1989-03-29 1995-03-28 Baran; Gregory W. Automated biopsy instrument
USRE34056E (en) 1989-07-31 1992-09-08 C.R. Bard, Inc. Tissue sampling device
US4921013A (en) * 1989-08-21 1990-05-01 Aeroquip Corporation Coupling adapter
JPH0395616A (en) 1989-09-08 1991-04-22 Toshiba Corp Keyboard connection control system
US5012605A (en) 1989-10-23 1991-05-07 Nishioka Jim Z Trigger cover
US4976269A (en) 1989-10-26 1990-12-11 Creative Research & Manufacturing Tissue needle
US5341816A (en) 1989-11-06 1994-08-30 Allen William C Biopsy device
US5172702A (en) 1989-11-24 1992-12-22 Medical Device Technologies, Inc. Disposable spring-loaded soft tissue biopsy apparatus
US5036860A (en) 1989-11-24 1991-08-06 Medical Device Technologies, Inc. Disposable soft tissue biopsy apparatus
US5057085A (en) 1989-11-24 1991-10-15 Medical Device Technologies, Inc. Stabilized aspiration biopsy needle assembly
US5074311A (en) 1989-12-06 1991-12-24 Hasson Harrith M Biopsy device
US5172701A (en) * 1990-02-28 1992-12-22 Medical Device Technologies, Inc. Single use automated soft tissue aspiration biopsy device
US5040542A (en) 1990-03-05 1991-08-20 Norman Gray Bone biopsy needle
US5120312A (en) 1990-04-20 1992-06-09 Regents Of The University Of Minnesota Method and apparatus for catheterization
US5145369A (en) 1990-04-23 1992-09-08 L. Paul Lustig Dental tool driving apparatus having rotating and roto-reciprocating motions
US5269785A (en) 1990-06-28 1993-12-14 Bonutti Peter M Apparatus and method for tissue removal
US5176415A (en) 1990-08-16 1993-01-05 Choksi Pradip V Taper fitting with protective skirt
US5990382A (en) * 1990-08-29 1999-11-23 Biomedical Enterprises, Inc. Method and implant for surgical manipulation of bone
US5030207A (en) 1990-11-02 1991-07-09 Becton, Dickinson And Company Instantaneous vein entry indicator for intravenous needle
US5685820A (en) 1990-11-06 1997-11-11 Partomed Medizintechnik Gmbh Instrument for the penetration of body tissue
DE4035146A1 (en) 1990-11-06 1992-05-07 Riek Siegfried INSTRUMENT FOR PENETRATING BODY TISSUE
IL96352A (en) 1990-11-14 1994-11-11 Du Kedem Tech Ltd Hard tissue biopsy instrument
WO1992008410A1 (en) 1990-11-14 1992-05-29 Kedem, Hadar Hard tissue biopsy instrument
US5148813A (en) 1990-11-20 1992-09-22 Bucalo Brian D Biopsy instrument with tissue specimen retaining and retrieval device
DE4039399A1 (en) * 1990-12-10 1992-06-11 Siteg Siebtech Gmbh DOUBLE SPIRAL, THEIR PRODUCTION AND THEIR USE FOR THE PRODUCTION OF A SPIRAL LINK STRAP
GB9100147D0 (en) 1991-01-04 1991-02-20 Smiths Industries Plc Tracheal tube assemblies and liners
US5261891A (en) 1991-01-15 1993-11-16 Ethicon, Inc. Trocar
US5104382A (en) 1991-01-15 1992-04-14 Ethicon, Inc. Trocar
US5354287A (en) 1991-01-16 1994-10-11 Senetek Plc Injector for delivering fluid to internal target tissue
US5249583A (en) 1991-02-01 1993-10-05 Vance Products Incorporated Electronic biopsy instrument with wiperless position sensors
US5984919A (en) 1991-02-13 1999-11-16 Applied Medical Resources Corporation Surgical trocar
US5599347A (en) 1991-02-13 1997-02-04 Applied Medical Resources Corporation Surgical trocar with cutoff circuit
DE69229902T2 (en) 1991-02-13 2000-05-04 Applied Med Resources SURGICAL TROCAR
US5075994A (en) 1991-03-19 1991-12-31 Nishioka Jim Z Trigger cover
US5405362A (en) 1991-04-29 1995-04-11 The Board Of Regents For The University Of Texas System Interactive external defibrillation and drug injection system
US5271744A (en) 1991-04-29 1993-12-21 George C. Kramer System and method for rapid vascular drug delivery
US5868711A (en) 1991-04-29 1999-02-09 Board Of Regents, The University Of Texas System Implantable intraosseous device for rapid vascular access
US5176643A (en) 1991-04-29 1993-01-05 George C. Kramer System and method for rapid vascular drug delivery
US5244619A (en) 1991-05-03 1993-09-14 Burnham Warren R Method of making catheter with irregular inner and/or outer surfaces to reduce travelling friction
US5137500A (en) 1991-05-22 1992-08-11 The Chamberlain Group, Inc. Sprocket conversion kit for garage door opener
DE4118732A1 (en) * 1991-06-07 1992-12-10 Joka Kathetertechnik Gmbh HOSE CLAMP FOR MEDICAL PURPOSES
US5116324A (en) * 1991-07-15 1992-05-26 Brierley Carol L Protector for IV site
US5207303A (en) 1991-07-15 1993-05-04 Oswalt Brenda K Medical emergency carrying case
US5385553A (en) * 1991-07-18 1995-01-31 Applied Medical Resources Corporation Trocar with floating septum seal
US5261877A (en) * 1991-07-22 1993-11-16 Dow Corning Wright Method of performing a thrombectomy procedure
US5187422A (en) 1991-07-31 1993-02-16 Stryker Corporation Charger for batteries of different type
USD338270S (en) 1991-08-07 1993-08-10 Ethicon, Inc. Adjustable trocar stabilizing collar
US5183054A (en) 1991-09-09 1993-02-02 Sherwood Medical Company Actuated biopsy cutting needle with removable stylet
US5312361A (en) 1991-09-13 1994-05-17 Zadini Filiberto P Automatic cannulation device
US5210376A (en) 1991-10-25 1993-05-11 Imperial Underground Sprinkler Co. Sealed electrical connection device and method
US5320110A (en) * 1991-10-29 1994-06-14 Wang Ko P Pleural biopsy syringe-needles
US5159163A (en) 1991-11-27 1992-10-27 Otis Elevator Company Elevator management system time based security
US5361853A (en) 1991-11-29 1994-11-08 Ryobi Limited Power tool
US5766221A (en) 1991-12-03 1998-06-16 Boston Scientific Technology, Inc. Bone anchor implantation device
US5462062A (en) 1991-12-13 1995-10-31 Rubinstein; Daniel B. Bone marrow biopsy needle with cutting and/or retaining device at distal end
US6358239B1 (en) 1992-01-24 2002-03-19 I-Flow Corporation Platen pump
US5339831A (en) 1992-01-30 1994-08-23 Baxter International Inc. Pouch within a pouch design
US5209721A (en) 1992-01-31 1993-05-11 Wilk Peter J Laparoscopic surgical device and related method
US5290276A (en) * 1992-02-06 1994-03-01 Sewell Jr Frank Rotatable laparoscopic puncturing instrument
DE4204947A1 (en) 1992-02-19 1993-08-26 Scintilla Ag POWERED HAND MACHINE
US5436566A (en) 1992-03-17 1995-07-25 Conmed Corporation Leakage capacitance compensating current sensor for current supplied to medical device loads
US5432459A (en) 1992-03-17 1995-07-11 Conmed Corporation Leakage capacitance compensating current sensor for current supplied to medical device loads with unconnected reference conductor
US5300070A (en) 1992-03-17 1994-04-05 Conmed Corporation Electrosurgical trocar assembly with bi-polar electrode
US5156399A (en) 1992-03-18 1992-10-20 Robert Gauer Golf glove-supported golf swing aid
US5595186A (en) * 1992-04-06 1997-01-21 Alan I. Rubinstein Bone marrow biopsy needle
US5499997A (en) 1992-04-10 1996-03-19 Sharpe Endosurgical Corporation Endoscopic tenaculum surgical instrument
US5318589A (en) 1992-04-15 1994-06-07 Microsurge, Inc. Surgical instrument for endoscopic surgery
US5333790A (en) 1992-04-20 1994-08-02 Christopher Gilman O Quick disconnect nozzle apparatus
US5334169A (en) 1992-05-11 1994-08-02 American Interventional Technologies, Inc. Reinforced catheter with thin monolithic walls
WO1993025151A1 (en) 1992-06-12 1993-12-23 Larry Steven Nichter Wire driver and method
US5315737A (en) * 1992-06-29 1994-05-31 Serge Ouimet Worm drive clamp with band guide channels
US5334204A (en) 1992-08-03 1994-08-02 Ace Medical Company Fixation screw
US5527290A (en) 1992-08-10 1996-06-18 Zadini; Filiberto Semi-automatic cannulation device or manually triggered self-propelled catheter cannulation device
US5271414A (en) 1992-09-30 1993-12-21 Becton, Dickinson And Company Biopsy cannula having non-cylindrical interior
IL107038A (en) 1992-10-05 1997-04-15 Senetek Plc Medicament injectors and methods for injection using same
US5318543A (en) 1992-10-08 1994-06-07 Abbott Laboratories Laparoscopic jejunostomy instrumentation kit
JPH06132663A (en) 1992-10-21 1994-05-13 Murata Mfg Co Ltd Manufacture of multilayer interconnection board
US5312408A (en) * 1992-10-21 1994-05-17 Brown Byron L Apparatus and method of cutting and suctioning the medullary canal of long bones prior to insertion of an endoprosthesis
US5313733A (en) 1992-10-28 1994-05-24 Meade Ronald A Quick release safety device for firearms
US5372583A (en) 1992-11-25 1994-12-13 Cardiopulmonary Specialities, Inc. Bone marrow infuser and method of use
US5357979A (en) 1992-12-01 1994-10-25 Intelliwire, Inc. Flexible elongate device having a distal extremity with current controlled adjustable stiffness and adjustable bend location and method
US5331972A (en) 1992-12-03 1994-07-26 Baxter International Inc. Bone marrow biopsy, aspiration and transplant needles
US5257972A (en) 1992-12-04 1993-11-02 Simon Gurmarnik Device for and method of length determination of epidural anesthesia catheter
US5356006A (en) 1992-12-16 1994-10-18 Ethicon, Inc. Sterile package for surgical devices
US5312351A (en) 1993-01-29 1994-05-17 Gerrone Carmen J Combined pneumo-needle and trocar apparatus
US5405348A (en) * 1993-02-12 1995-04-11 Anspach, Jr.; William E. Surgical cutting instrument
US5330480A (en) 1993-03-03 1994-07-19 Codman & Shurtleff, Inc. Surgical drill
US5357974A (en) 1993-03-04 1994-10-25 Thomas F. Robinson Bone marrow biopsy instrument
US5307924A (en) 1993-03-26 1994-05-03 Abbott Laboratories Packaging for T-shaped tension devices
US5366445A (en) * 1993-03-30 1994-11-22 Habley Medical Technology Corp. Trocar with rotating safety shield
US5449370A (en) 1993-05-12 1995-09-12 Ethicon, Inc. Blunt tipped ultrasonic trocar
US5526821A (en) 1993-06-03 1996-06-18 Medical Biopsy, Inc. Biopsy needle with sample retaining means
US5389553A (en) * 1993-06-30 1995-02-14 National Semiconductor Corporation Methods for fabrication of transistors
US5549565A (en) * 1993-07-13 1996-08-27 Symbiosis Corporation Reusable surgical trocar with disposable valve assembly
US5454791A (en) 1993-09-07 1995-10-03 United States Surgical Corporation Trocar with tissue penetration pressure indicator
US5423796A (en) 1993-10-08 1995-06-13 United States Surgical Corporation Trocar with electrical tissue penetration indicator
US5421821A (en) 1993-11-12 1995-06-06 Marlow Surgical Technologies, Inc. Verres needle system and method
US5407243A (en) 1993-12-10 1995-04-18 Riemann; Mathew W. Tick removing device
US6248110B1 (en) 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US6241734B1 (en) 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
US6716216B1 (en) * 1998-08-14 2004-04-06 Kyphon Inc. Systems and methods for treating vertebral bodies
US5514097A (en) 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
GB9405002D0 (en) 1994-03-15 1994-04-27 Univ Manitoba Apparatus and method of use for pulsatile blood flow with return of in vivo variability of the pulse waveform
US5526822A (en) * 1994-03-24 1996-06-18 Biopsys Medical, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
USD369858S (en) 1994-06-14 1996-05-14 Medical Device Technologies, Inc. Combined biopsy stylet and biopsy cannula
US5476102A (en) 1994-06-29 1995-12-19 Baxter International Inc. Biopsy needle assembly and guide
US5505737A (en) 1994-07-01 1996-04-09 Midas Rex Pneumatic Tools, Inc. Quick release coupling for a dissecting tool
CA2150663A1 (en) 1994-07-22 1996-01-23 William Ishmael Control system
US6270087B1 (en) 1994-07-27 2001-08-07 Mednext, Inc. Tool shaft coupler
US5497787A (en) 1994-08-05 1996-03-12 Nemesdy; Gabor Limb monitoring method and associated apparatus
US5437119A (en) 1994-08-16 1995-08-01 Weinraub Enterprises, Inc. Gun trigger blocking structure
GB9417399D0 (en) 1994-08-30 1994-10-19 Scherer Corp R P Ocular treatment device
AU3546395A (en) 1994-09-09 1996-03-27 Ryobi North America, Inc. Attachment system for battery powered tool
US5526820A (en) 1994-09-19 1996-06-18 Myelotec, Inc. Catheter with integral pressure sensor
US5533843A (en) 1994-09-19 1996-07-09 Chung; Lee H.-C. Electric hand drill set
US5591119A (en) 1994-12-07 1997-01-07 Adair; Edwin L. Sterile surgical coupler and drape
US6080092A (en) 1994-10-06 2000-06-27 Xomed Surgical Products, Inc. Industrial cleaning sponge
US5533978A (en) 1994-11-07 1996-07-09 Teirstein; Paul S. Method and apparatus for uninterrupted delivery of radiographic dye
JP3079921B2 (en) * 1994-11-28 2000-08-21 松下電器産業株式会社 Solder ball mounting device and mounting method
US5525842A (en) 1994-12-02 1996-06-11 Volt-Aire Corporation Air tool with integrated generator and light ring assembly
CA2138842A1 (en) * 1994-12-22 1996-06-23 David E. Gibbs Catheterized intra-osseus delivery system
US6321855B1 (en) 1994-12-29 2001-11-27 George Edward Barnes Anti-vibration adaptor
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5556399A (en) 1995-02-14 1996-09-17 Huebner; Randall J. Bone-harvesting drill apparatus and method for its use
US5782835A (en) * 1995-03-07 1998-07-21 Innovasive Devices, Inc. Apparatus and methods for articular cartilage defect repair
US5571133A (en) 1995-06-01 1996-11-05 Yoon; Inbae Penetrating instrument with sequential indication of entry into anatomical cavities
CH690905A5 (en) 1995-06-14 2001-02-28 Sodem Diffusion Sa And process connection device and surgical instrument for driving interchangeable rotary tools.
US5807275A (en) 1995-07-19 1998-09-15 Medical Biopsy, Inc. Biopsy needle
DE19527193A1 (en) 1995-07-26 1997-01-30 Hilti Ag Screwdriver
US5738177A (en) 1995-07-28 1998-04-14 Black & Decker Inc. Production assembly tool
US5704435A (en) 1995-08-17 1998-01-06 Milwaukee Electric Tool Corporation Hand held power tool including inertia switch
US5687802A (en) 1995-09-21 1997-11-18 Chicago Pneumatic Tool Company Power hand tool with rotatable handle
US5712543A (en) 1995-10-31 1998-01-27 Smith & Nephew Endoscopy Inc. Magnetic switching element for controlling a surgical device
US5769086A (en) 1995-12-06 1998-06-23 Biopsys Medical, Inc. Control system and method for automated biopsy device
US5807277A (en) 1995-12-15 1998-09-15 Swaim; William R. Biopsy hand tool for capturing tissue sample
US5624214A (en) 1995-12-15 1997-04-29 Carroll; Stuart Adjustable drill bit extension
IL116685A (en) 1996-01-05 2000-07-16 Vascular Technologies Ltd Blood vessel entry indicator
US5713149A (en) 1996-01-11 1998-02-03 Trigger Block, Inc. Electronic trigger lock
US6749576B2 (en) 1996-01-26 2004-06-15 Allegiance Corporation Biopsy device with adjustable sampling
US5916229A (en) 1996-02-07 1999-06-29 Evans; Donald Rotating needle biopsy device and method
US5800389A (en) 1996-02-09 1998-09-01 Emx, Inc. Biopsy device
FR2744629B1 (en) 1996-02-13 1998-05-22 Advanced Technical Fabrication HIP PROSTHESIS INSTRUMENTATION
DE29603447U1 (en) 1996-02-26 1996-04-18 Aesculap Ag Drilling machine for surgical purposes
US5823970A (en) 1996-03-22 1998-10-20 Medical Device Technologies, Inc. Biopsy needle set
US6152918A (en) 1996-04-05 2000-11-28 Eclipse Surgical Technologies, Inc. Laser device with auto-piercing tip for myocardial revascularization procedures
US5733262A (en) * 1996-04-18 1998-03-31 Paul; Kamaljit S. Blood vessel cannulation device
JP3240923B2 (en) * 1996-05-10 2001-12-25 日立工機株式会社 Multi-stroke driving machine
IE80772B1 (en) 1996-06-10 1999-02-10 Elan Corp Plc Delivery needle
US5672155A (en) * 1996-06-14 1997-09-30 Riley; Robert Q. Fluid transfer apparatus
US5762498A (en) 1996-06-18 1998-06-09 Gonzalez; Arnaldo Dental drill bit
US5752923A (en) 1996-06-24 1998-05-19 Medical Device Technologies, Inc. Biopsy instrument with handle and needle set
USD403405S (en) 1996-06-24 1998-12-29 Medical Device Technologies, Inc. Biopsy needle set
US5724873A (en) * 1996-07-12 1998-03-10 Hillinger; George Composite magnetic-field screwdriver
US5941851A (en) * 1996-07-12 1999-08-24 C.R. Bard, Inc. Pulsed lavage handpiece with improved handle
DE69631669T2 (en) 1996-07-16 2004-12-02 Fire-Trol Holdings, L.L.C., Phoenix DOSING VALVE AND CONTROL DEVICE THEREFOR
US5919172A (en) 1996-07-17 1999-07-06 Becton, Dickinson And Company Hypodermic needle having a differential surface finish
US6033408A (en) 1996-07-30 2000-03-07 Midas Rex, L.P. Resecting tool for magnetic field environment
US5873499A (en) 1996-08-14 1999-02-23 Scientific Resources, Inc. Pressure breakaway dispensing gun
US6017354A (en) 1996-08-15 2000-01-25 Stryker Corporation Integrated system for powered surgical tools
US5921987A (en) 1996-09-13 1999-07-13 Depuy Orthopaedic Technology, Inc. Articular cartilage transplant instrument set
JP3986597B2 (en) 1996-10-15 2007-10-03 関東電化工業株式会社 Method for treating nitrogen trifluoride-containing gas and treating agent therefor
JP3667477B2 (en) 1996-12-09 2005-07-06 滲透工業株式会社 Gas carburizing furnace parts and jigs
US5947989A (en) * 1996-12-12 1999-09-07 United States Surgical Corporation Method and apparatus for transmyocardial revascularization
US6027458A (en) * 1996-12-23 2000-02-22 Janssens; Jacques Phillibert Device for taking a tissue sample
US6007496A (en) 1996-12-30 1999-12-28 Brannon; James K. Syringe assembly for harvesting bone
IT1290628B1 (en) 1997-01-03 1998-12-10 Gallini Srl DEVICE FOR THE EXECUTION OF BIOPSIES
JP3577921B2 (en) 1997-01-13 2004-10-20 株式会社村田製作所 Dielectric filter and dielectric duplexer
US5873580A (en) * 1997-01-17 1999-02-23 Commando Products, Inc. Tool holder with interchangeable collet/chuck system
CN2294028Y (en) 1997-03-25 1998-10-14 顾利华 Removabe chargeable drill for bone
US5893851A (en) 1997-04-18 1999-04-13 Midas Rex Pneumatic Tools, Inc. Multiple chuck resecting tool
US5902306A (en) 1997-05-01 1999-05-11 Linvatec Corporation Surgical wire driver with one-handed gripping attachment
US7347840B2 (en) 2000-03-02 2008-03-25 Pyng Medical Corp. Patch for locating a target zone for penetration
CA2205623A1 (en) 1997-05-16 1998-11-16 Pyng Medical Corp. Method and apparatus for intraosseous infusion and aspiration using an automatic release mechanism
US6050754A (en) 1997-05-29 2000-04-18 Black & Decker Inc. Self-centering drill bit with pilot tip, and process
US5938636A (en) 1997-06-20 1999-08-17 The Bd Of Regents Of The University Of California Autoinfuser for resuscitation and method of infusion fluid injection
US6171276B1 (en) 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
US5858005A (en) * 1997-08-27 1999-01-12 Science Incorporated Subcutaneous infusion set with dynamic needle
US5960575A (en) 1997-09-22 1999-10-05 Chiovitt; Joseph R. Trigger guard lock for a firearm
US6716192B1 (en) * 1997-09-30 2004-04-06 Charles F. Schroeder Medical needle having a visibly marked tip
DE69720447T2 (en) * 1997-10-06 2003-12-24 Pirelli Reinforcing fabric for an article made of elastomeric material and article containing such fabric
US6033411A (en) 1997-10-14 2000-03-07 Parallax Medical Inc. Precision depth guided instruments for use in vertebroplasty
US6049725A (en) 1997-10-15 2000-04-11 Motorola, Inc. Charging cradle
US5926989A (en) 1997-10-16 1999-07-27 Oliver, Sr.; Frank Trigger finger stop assembly
US5868750A (en) * 1997-11-03 1999-02-09 Spectrum Surgical Instruments, Inc. Orthopedic pin insertion tool
US5865711A (en) * 1997-11-12 1999-02-02 Chen; Ping Exercise bicycle
CN2320209Y (en) 1997-12-03 1999-05-26 山东省滨州地区人民医院 Simple marrow puncture needle
US5951026A (en) 1997-12-12 1999-09-14 Black & Decker Inc. Removable chuck
US6550786B2 (en) 1997-12-12 2003-04-22 Black & Decker Inc. Removable chuck
US6076152A (en) 1997-12-17 2000-06-13 Src Computers, Inc. Multiprocessor computer architecture incorporating a plurality of memory algorithm processors in the memory subsystem
US5993417A (en) 1998-01-06 1999-11-30 Yerfino; Daniel Alberto Disposable syringe with an automatically retractable hypodermic needle
USD404458S (en) 1998-01-13 1999-01-19 Pruitt Bobby E Trigger guard
US6007495A (en) * 1998-01-22 1999-12-28 United States Surgical Corporation Biopsy apparatus and method
US5921562A (en) 1998-01-27 1999-07-13 Robison; Troy Magnetic chuck assembly
US6468279B1 (en) 1998-01-27 2002-10-22 Kyphon Inc. Slip-fit handle for hand-held instruments that access interior body regions
US5911701A (en) 1998-01-29 1999-06-15 Sdgi Holidings, Inc. Surgical cutting instrument
US6098042A (en) 1998-01-30 2000-08-01 International Business Machines Corporation Homograph filter for speech synthesis system
DE19806693A1 (en) 1998-02-18 1999-08-19 Daum Gmbh Telescopically working needle and tube system for removal of tumor
US6193673B1 (en) * 1998-02-20 2001-02-27 United States Surgical Corporation Biopsy instrument driver apparatus
JP3559441B2 (en) 1998-03-05 2004-09-02 テルモ株式会社 Tube unit system
US5989257A (en) 1998-03-11 1999-11-23 Midas Rex L.P. Redundant safety lock mechanism
JP3527405B2 (en) 1998-03-18 2004-05-17 株式会社マキタ Power tool charging system
US7572263B2 (en) 1998-04-01 2009-08-11 Arthrocare Corporation High pressure applicator
US5954671A (en) * 1998-04-20 1999-09-21 O'neill; Michael J. Bone harvesting method and apparatus
US6159163A (en) 1998-05-07 2000-12-12 Cedars-Sinai Medical Center System for attenuating pain during bone marrow aspiration and method
US6106484A (en) 1998-05-12 2000-08-22 Medical Device Technologies, Inc. Reusable automated biopsy needle handle
US6283925B1 (en) 1998-05-12 2001-09-04 Medical Device Technologies, Inc. Biopsy needle handle
US6083176A (en) 1998-08-11 2000-07-04 Medical Device Technologies, Inc. Automated biopsy needle handle
US6018230A (en) 1998-06-15 2000-01-25 Casey; John P. Apparatus and method for interrupting charging of self-charging electronic device
US6086543A (en) 1998-06-24 2000-07-11 Rubicor Medical, Inc. Fine needle and core biopsy devices and methods
US6102887A (en) 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
US6063037A (en) 1998-08-21 2000-05-16 Manan Medical Products, Inc. Bone marrow biopsy needle
US6872187B1 (en) 1998-09-01 2005-03-29 Izex Technologies, Inc. Orthoses for joint rehabilitation
US5993454A (en) 1998-09-29 1999-11-30 Stryker Corporation Drill attachment for a surgical drill
US6015391A (en) 1998-10-06 2000-01-18 Medsol, Corp. Biopsy needle structure
CA2287087C (en) 1998-10-23 2007-12-04 Ethicon Endo-Surgery, Inc. Surgical device for the collection of soft tissue
US6309258B1 (en) 1998-10-23 2001-10-30 Cooper Industries, Inc. Single pole cable connector
US20010047183A1 (en) 2000-04-05 2001-11-29 Salvatore Privitera Surgical device for the collection of soft tissue
JP2000171671A (en) 1998-12-09 2000-06-23 Matsushita Electric Ind Co Ltd Optical communication module and its mounting method
US6110128A (en) 1998-12-11 2000-08-29 Andelin; John B. Bone marrow biopsy needle and method for using the same
US6126670A (en) 1998-12-16 2000-10-03 Medtronic, Inc. Cordless surgical handpiece with disposable battery; and method
US6025683A (en) 1998-12-23 2000-02-15 Stryker Corporation Motor control circuit for regulating a D.C. motor
US6162203A (en) 1999-01-11 2000-12-19 Haaga; John R. Cargo delivery needle
US7189206B2 (en) 2003-02-24 2007-03-13 Senorx, Inc. Biopsy device with inner cutter
DE29901723U1 (en) 1999-02-02 2000-06-29 Synthes Ag Device for extracting bone chips
US6053884A (en) * 1999-02-18 2000-04-25 Athlete Protection Gear, Llc Ankle brace with cuff
US6080115A (en) 1999-02-24 2000-06-27 Rubinstein; Alan I. Bone marrow biopsy needle
US6549511B1 (en) 1999-02-24 2003-04-15 Hewlett Packard Development Company, L.P. Optical disk medium having features for radial tilt detection and apparatus for measuring radial tilt
JP4638051B2 (en) * 1999-03-19 2011-02-23 ヴァイダケア、コーパレイシャン Biopsy needle
US6402701B1 (en) 1999-03-23 2002-06-11 Fna Concepts, Llc Biopsy needle instrument
US6086544A (en) 1999-03-31 2000-07-11 Ethicon Endo-Surgery, Inc. Control apparatus for an automated surgical biopsy device
US6267763B1 (en) * 1999-03-31 2001-07-31 Surgical Dynamics, Inc. Method and apparatus for spinal implant insertion
US6120462A (en) 1999-03-31 2000-09-19 Ethicon Endo-Surgery, Inc. Control method for an automated surgical biopsy device
US6154995A (en) 1999-04-07 2000-12-05 Lenoir; Richard C. Trigger cover for firearm
US6242009B1 (en) 1999-04-20 2001-06-05 Kareem I. Batarseh Microbicidal formulations and methods to control microorganisms
US6187768B1 (en) 1999-06-01 2001-02-13 Becton, Dickinson And Company Kit for flushing medical devices and method of preparation
US6626887B1 (en) 1999-06-08 2003-09-30 Intravantage, Inc. Hard tissue drug delivery device and method
US6575745B2 (en) 2000-12-05 2003-06-10 Tulsa Dental Products Inc. Titanium alloy intraosseous anesthesia delivery device
US6616579B1 (en) 1999-06-14 2003-09-09 Sensorpad Systems, Inc. Apparatus for isometric exercise
US6272007B1 (en) 1999-06-28 2001-08-07 Sun Microsystems, Inc. Computer system cooling configuration
IT1313279B1 (en) 1999-07-30 2002-07-17 Makita S P A LIGHTING DEVICE FOR ELECTRIC MACHINE TOOLS AND MACHINE TOOL INCLUDING SUCH DEVICE.
US6349496B1 (en) 1999-08-31 2002-02-26 George Joseph Neely Safety locking device for a firearm
US6302409B1 (en) * 1999-09-10 2001-10-16 Gunter Emil Gutsche Elements for a magnetic tool holder system
US6500180B1 (en) * 1999-10-20 2002-12-31 Sdgi Holdings, Inc. Methods and instrumentation for distraction of a disc space
US6308540B1 (en) 1999-10-22 2001-10-30 Li-Chiue Lee Cable-type fastening device for pistol trigger lock
US6716215B1 (en) * 1999-10-29 2004-04-06 Image-Guided Neurologics Cranial drill with sterile barrier
DE19954373B4 (en) 1999-11-11 2011-01-27 Helvoet Pharma Belgium N.V. Protective cap for a cannula
US6446734B1 (en) 1999-11-11 2002-09-10 Black & Decker Inc. Motor/handle housing and gear case mounting for portable power tool
US6585622B1 (en) 1999-12-03 2003-07-01 Nike, Inc. Interactive use an athletic performance monitoring and reward method, system, and computer program product
US6428487B1 (en) 1999-12-17 2002-08-06 Ethicon Endo-Surgery, Inc. Surgical biopsy system with remote control for selecting an operational mode
DK176336B1 (en) 1999-12-22 2007-08-20 Asahi Optical Co Ltd Endoscopic tissue collection instrument
US6382212B1 (en) 2000-01-18 2002-05-07 Medtronic, Inc. Fenestrated surgical drape with in situ features
US6458117B1 (en) * 2000-01-19 2002-10-01 Kevin Daniel Pollins, Sr. Intraosseous infusion assembly and method for intraosseous infusion
US6702761B1 (en) * 2000-03-06 2004-03-09 Fonar Corporation Vibration assisted needle device
EP1769887B1 (en) 2000-03-16 2008-07-30 Makita Corporation Power tools
US6770070B1 (en) 2000-03-17 2004-08-03 Rita Medical Systems, Inc. Lung treatment apparatus and method
US6416484B1 (en) 2000-03-24 2002-07-09 Promex, Inc. Biopsy extractor
WO2001072369A1 (en) * 2000-03-29 2001-10-04 Bioaccess, Inc. System and method for processing bone marrow
US7201722B2 (en) * 2000-04-18 2007-04-10 Allegiance Corporation Bone biopsy instrument having improved sample retention
US6730043B2 (en) 2000-04-18 2004-05-04 Allegiance Corporation Bone marrow biopsy needle
US6443910B1 (en) 2000-04-18 2002-09-03 Allegiance Corporation Bone marrow biopsy needle
WO2001087739A1 (en) 2000-05-12 2001-11-22 Lindon Products, Inc. Cases for medication delivery devices
US6425388B1 (en) 2000-05-22 2002-07-30 The Garland Group Pizza oven deck
DE20009786U1 (en) * 2000-05-31 2000-10-19 Taufig Ahmmed Ziah Liposuction device
US6537242B1 (en) 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6394979B1 (en) 2000-06-09 2002-05-28 Inviro Medical Devices Ltd. Cannula for use with a medical syringe
US6890279B2 (en) * 2000-06-09 2005-05-10 Vkr Holding A/S Window operator
US6450973B1 (en) 2000-06-16 2002-09-17 Kieran P. J. Murphy Biopsy gun
US6462448B1 (en) 2000-07-05 2002-10-08 Black & Decker Inc. Flux ring for an electric motor
JP2002019122A (en) 2000-07-10 2002-01-23 Canon Inc Substrate for ink jet recording head, ink jet recording head and method of manufacturing the head
DE10034079A1 (en) 2000-07-13 2002-01-24 Heidenhain Gmbh Dr Johannes Device and method for controlling a machine tool
IT1316915B1 (en) 2000-07-20 2003-05-13 Hs Hospital Service Spa TRANSCUTANEOUS BIOPSY DEVICE FOR RIGID TISSUES.
IT1317102B1 (en) 2000-07-24 2003-05-26 Pietro Castellacci NEEDLE OF THE BIOPSY TYPE OR FOR OTHER WITHDRAWALS FROM HUMAN OR DIANIMAL ORGANS.
DE60124990T2 (en) 2000-07-29 2007-09-20 Worldwide Medical Technologies, Woodbury Tool for extracting bone marrow
US6641395B2 (en) 2000-08-02 2003-11-04 Nobel Biocare Ab Endosseous implant drill
DE50101865D1 (en) * 2000-08-09 2004-05-06 Fraunhofer Ges Forschung ARRANGEMENT WITH VARIABLE CAPACITY
US6712773B1 (en) 2000-09-11 2004-03-30 Tyco Healthcare Group Lp Biopsy system
US6730044B2 (en) 2000-10-13 2004-05-04 Ethicon Endo-Surgery, Inc. Firing mechanism for use in a surgical biopsy device
US6656133B2 (en) 2000-10-13 2003-12-02 Ethicon Endo-Surgery, Inc. Transmission assembly for a surgical biopsy device
US6540694B1 (en) * 2000-10-16 2003-04-01 Sanarus Medical, Inc. Device for biopsy tumors
AU1156802A (en) 2000-10-16 2002-04-29 Sanarus Medical Inc Device for biopsy of tumors
DE10051591A1 (en) 2000-10-18 2002-05-02 Festo Ag & Co Bus Repeater
US6527736B1 (en) * 2000-10-23 2003-03-04 Grieshaber & Co. Ag Schaffhausen Device for use in ophthalmologic procedures
US6547511B1 (en) * 2000-10-30 2003-04-15 Owens Corning Fiberglas Technology, Inc. Process of loading rolls of roofing material onto a pallet
US7491176B2 (en) 2000-11-01 2009-02-17 Vascular Biosciences Kit for obtaining an endoarterial biopsy sample
US6758824B1 (en) 2000-11-06 2004-07-06 Suros Surgical Systems, Inc. Biopsy apparatus
AU2002245125A1 (en) * 2000-11-06 2002-07-08 Francis C. Classe Biopsy and coagulant device
US7458940B2 (en) * 2000-11-06 2008-12-02 Suros Surgical Systems, Inc. Biopsy apparatus
JP4064243B2 (en) * 2000-11-06 2008-03-19 スルーズ サージカル システムズ、インク Biological tissue examination device
DE10057831A1 (en) 2000-11-21 2002-05-23 Knf Flodos Ag Sursee Membrane pump
DE10057931B4 (en) 2000-11-22 2007-11-08 Lell, Peter, Dr.-Ing. Pyrotechnic surgical instrument (Pyronadel)
FR2816824B1 (en) 2000-11-23 2003-05-23 Michel Kurc BONE RECOVERY BIT AND DRILLING DEVICE COMPRISING SUCH A BIT
EP1404214A2 (en) * 2000-11-24 2004-04-07 CKM Diagnostics, Inc. Nerve stimulator output control needle with depth determination capability and method of use
US6520971B1 (en) 2000-11-27 2003-02-18 Scimed Life Systems, Inc. Full thickness resection device control handle
WO2002041787A2 (en) * 2000-11-27 2002-05-30 Tyco Healthcare Group Lp Tissue sampling and removal apparatus and method
IT1316978B1 (en) 2000-12-28 2003-05-13 Hs Hospital Service Spa DEVICE FOR TRANSCUTANEOUS BIOPSY OF RIGID TISSUES, IN PARTICULAR OSTEOMIDOLLAR TISSUE.
DE10100027B4 (en) 2001-01-03 2005-07-14 Schweiger, Bernd Change holder for hollow drill
US6626173B2 (en) 2001-01-08 2003-09-30 Iep Pharmaceutical Devices Inc. Dry powder inhaler
JP4111829B2 (en) 2001-01-11 2008-07-02 リタ メディカル システムズ インコーポレイテッド Bone treatment instrument
US6511440B2 (en) 2001-01-22 2003-01-28 Long Hsiung Chen Safety vacuum syringe for blood sampling conformed to ergonomics
US6431289B1 (en) 2001-01-23 2002-08-13 Black & Decker Inc. Multi-speed power tool transmission
US6451023B1 (en) 2001-01-25 2002-09-17 Linvatec Corporation Guide bushing for coring reamer, storage package for reamer assembly, and method of use
US6419490B1 (en) 2001-01-30 2002-07-16 Arthur Kitchings Weathers, Jr. Grooved intraosseous dental drill bit
BE1013974A3 (en) * 2001-02-16 2003-01-14 Janssens Jacques Phillibert Device for taking a tissue language.
US7544196B2 (en) 2001-02-20 2009-06-09 Orthovita, Inc. System and kit for delivery of restorative materials
US6947669B2 (en) 2001-03-07 2005-09-20 Meriton Networks Inc. Generic optical routing information base support
JP2002271205A (en) 2001-03-09 2002-09-20 Victor Co Of Japan Ltd Modulation method, modulator, demodulation method, demodulator, information recoding medium, information transmitting method and information transmitting equipment
US7001391B2 (en) 2001-03-21 2006-02-21 Medtronic, Inc. Surgical instrument with rotary cutting member and quick release coupling arrangement
WO2002076308A2 (en) 2001-03-21 2002-10-03 Medtronic, Inc. Surgical rotary cutting instrument with quick release coupling
US20020138021A1 (en) 2001-03-23 2002-09-26 Devonrex, Inc. Micro-invasive tissue removal device
US6626848B2 (en) 2001-03-30 2003-09-30 Eric M. Neuenfeldt Method and device to reduce needle insertion force
US6595911B2 (en) 2001-04-03 2003-07-22 Lovuolo Michael Method and device for anchor implantation and support of bodily structures
US6620111B2 (en) 2001-04-20 2003-09-16 Ethicon Endo-Surgery, Inc. Surgical biopsy device having automatic rotation of the probe for taking multiple samples
US7225959B2 (en) 2001-04-30 2007-06-05 Black & Decker, Inc. Portable, battery-powered air compressor for a pneumatic tool system
AUPR529101A0 (en) 2001-05-29 2001-06-21 Noble, David The utilisation of the intraosseous route for gas exchange
US6595979B1 (en) 2001-07-10 2003-07-22 Myocardial Therapeutics, Inc. Methods for sterile aspiration/reinjection of bodily fluid
US6796957B2 (en) 2001-07-10 2004-09-28 Myocardial Therapeutics, Inc. Sterile aspiration/reinjection systems
AU2002259265B2 (en) 2001-07-27 2008-06-05 Becton, Dickinson And Company Luer connector assembly
US6554809B2 (en) * 2001-08-02 2003-04-29 Teodulo Aves Epidural catheter needle
AU2002321889A1 (en) * 2001-08-03 2003-02-24 Stemsource Llc Devices and method for extraction of bone marrow
JP4058614B2 (en) 2001-08-09 2008-03-12 株式会社Jimro Bone marrow needle
US6786897B2 (en) 2001-08-16 2004-09-07 Linvatec Corporation Temperature indicator and insulator for powered surgical instruments
DK174792B1 (en) * 2001-09-07 2003-11-24 Coloplast As Packaging for an ostomy device
US7001342B2 (en) 2001-10-30 2006-02-21 Movdice Holding, Inc. Biopsy/access tool with integrated biopsy device and access cannula and use thereof
CA2465653C (en) * 2001-10-30 2013-10-08 Renomedix Institute Inc. Method for inducing differentiation of mesodermal stem cells, es cells, or immortalized mesodermal stem cells into neural cells
ES2246999T3 (en) 2001-11-23 2006-03-01 Nucletron B.V. AUTOCONTROLLED DEVICE GUIDED BY IMAGES TO INSERT A NEEDLE IN THE BODY OF AN ANIMAL TO PERFORM RADIOTHERAPY IN THIS BODY.
US6726649B2 (en) 2001-12-28 2004-04-27 Becton, Dickinson And Company Medical needle assemblies
US20030125639A1 (en) 2002-01-02 2003-07-03 Fisher John S. Biopsy needle having rotating core for shearing tissue
US7278972B2 (en) 2002-01-24 2007-10-09 Worldwide Medical Technologies, Llc Combined bone marrow aspiration and core biopsy device
AU2003236757B2 (en) * 2002-01-25 2009-12-03 Takeda Pharmaceutical Company Limited Process for producing dioxolane nucleoside analogues
US6887209B2 (en) 2002-01-25 2005-05-03 Advanced Medical Optics Pulsed vacuum and/or flow method and apparatus for tissue removal
DE10303235B4 (en) 2002-01-29 2011-03-31 Makita Corp., Anjo Torque-transmitting mechanisms and power tools with such torque-transmitting mechanisms
US8277411B2 (en) 2002-01-31 2012-10-02 Boston Scientific Scimed, Inc. Needle device
US20030149436A1 (en) 2002-02-04 2003-08-07 Mcdowell Charles L. Fixation and compression fastener assembly for bone fractures
FR2835732B1 (en) 2002-02-11 2004-11-12 Spinevision DEVICE FOR TRACKING THE PENETRATION OF A PENETRATION MEANS IN ANATOMICAL ELEMENTS
DE10207355C1 (en) 2002-02-19 2003-06-18 Aesculap Ag & Co Kg Fluid powered surgical drill has connector with thermally actuated closure to allow pressure fluid flow only above set temperature
US7169127B2 (en) 2002-02-21 2007-01-30 Boston Scientific Scimed, Inc. Pressure apron direct injection catheter
US6896141B2 (en) 2002-02-28 2005-05-24 Kimberly-Clark Worldwide, Inc. Surgical kit with multiple planar recess surfaces
US8043287B2 (en) 2002-03-05 2011-10-25 Kimberly-Clark Inc. Method of treating biological tissue
CA2479339C (en) 2002-03-19 2013-03-12 Bard Dublin Itc Limited Vacuum biopsy device
AU2003218696A1 (en) 2002-03-19 2003-09-29 Bard Dublin Itc Limited Biopsy device and biopsy needle module that can be inserted into the biopsy device
AU2003225869A1 (en) * 2002-03-20 2003-10-08 Board Of Regents, The University Of Texas System Biopsy needle
EP1492456B1 (en) 2002-04-05 2012-10-24 CareFusion 2200, Inc. Improved biopsy needle and biopsy device containing the same
US20030195524A1 (en) 2002-04-12 2003-10-16 Gil Barner Body tissue aspiration cannula
US6884245B2 (en) * 2002-04-22 2005-04-26 Spranza, Iii Joseph John Hardware for cutting bone cores
US20050075581A1 (en) 2002-04-23 2005-04-07 Jeffrey Schwindt Pneumatic circuit
US6917183B2 (en) 2002-05-01 2005-07-12 Linvatec Corporation Battery pack for sterile transfer battery container
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US9545243B2 (en) 2002-05-31 2017-01-17 Vidacare LLC Bone marrow aspiration devices and related methods
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
US7850620B2 (en) 2002-05-31 2010-12-14 Vidacare Corporation Biopsy devices and related methods
US9072543B2 (en) 2002-05-31 2015-07-07 Vidacare LLC Vascular access kits and methods
US7811260B2 (en) 2002-05-31 2010-10-12 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US8690791B2 (en) 2002-05-31 2014-04-08 Vidacare Corporation Apparatus and method to access the bone marrow
US8142365B2 (en) 2002-05-31 2012-03-27 Vidacare Corporation Apparatus and method for accessing the bone marrow of the sternum
US9314228B2 (en) 2002-05-31 2016-04-19 Vidacare LLC Apparatus and method for accessing the bone marrow
US10973532B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US7951089B2 (en) 2002-05-31 2011-05-31 Vidacare Corporation Apparatus and methods to harvest bone and bone marrow
US20070049945A1 (en) * 2002-05-31 2007-03-01 Miller Larry J Apparatus and methods to install, support and/or monitor performance of intraosseous devices
CA2498962A1 (en) 2002-06-04 2003-12-11 Office Of Technology Licensing Stanford University Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US7081123B2 (en) 2002-06-18 2006-07-25 Musculoskeletal Transplant Foundation Bone marrow aspiration instrument
US6916292B2 (en) 2002-07-12 2005-07-12 Depuy Spine, Inc. Bone marrow aspirator
AU2003255276A1 (en) 2002-08-13 2004-02-25 Arbios Systems, Inc. Selective plasma exchange therapy
US7331967B2 (en) 2002-09-09 2008-02-19 Hansen Medical, Inc. Surgical instrument coupling mechanism
AU2002335737A1 (en) 2002-09-11 2004-04-30 Nuvasive, Inc. Systems and methods for removing body tissue
US7326203B2 (en) * 2002-09-30 2008-02-05 Depuy Acromed, Inc. Device for advancing a functional element through tissue
US6709392B1 (en) 2002-10-10 2004-03-23 Koninklijke Philips Electronics N.V. Imaging ultrasound transducer temperature control system and method using feedback
US20040073139A1 (en) * 2002-10-11 2004-04-15 Hirsch Joshua A. Cannula for extracting and implanting material
US6880860B2 (en) * 2002-10-31 2005-04-19 Maria D. Atwood Fluid conducting elbow
US7351210B2 (en) 2002-12-11 2008-04-01 Ethicon-Endo-Surgery, Inc. Biopsy device with piston advance
US7740597B2 (en) 2002-12-11 2010-06-22 Ethicon Endo-Surgery, Inc. Biopsy device with sample tube
US20040127814A1 (en) 2002-12-12 2004-07-01 Carlos Negroni Biopsy assembly
US20040127818A1 (en) 2002-12-27 2004-07-01 Roe Steven N. Precision depth control lancing tip
US6790185B1 (en) 2002-12-31 2004-09-14 Biopsy Sciences, Llc Sealant plug delivery methods
US7063672B2 (en) 2003-01-31 2006-06-20 Inter-V Manan Integrated biopsy needle assembly
DE10303964A1 (en) 2003-01-31 2004-08-19 Wolfgang Prof. Dr. Oettinger Medical drilling device and medical drilling method
US7229419B2 (en) 2003-02-11 2007-06-12 Promex/U.S. Biosy Llc Single-handed biopsy system
US7252641B2 (en) * 2003-02-25 2007-08-07 Ethicon Endo-Surgery, Inc. Method of operating a biopsy device
WO2004075728A2 (en) 2003-02-25 2004-09-10 Ethicon Endo-Surgery, Inc. Biopsy device with variable speed cutter advance
MXPA05010221A (en) 2003-03-25 2006-02-22 Terry O Herndon Drill device and method for forming microconduits.
CA2520472A1 (en) 2003-03-31 2004-10-21 The Cleveland Clinic Foundation Apparatus and method for harvesting bone marrow
US7182752B2 (en) 2003-04-08 2007-02-27 Surgiquest, Incorporated Continuous gas flow trocar assembly
US7854724B2 (en) 2003-04-08 2010-12-21 Surgiquest, Inc. Trocar assembly with pneumatic sealing
US7338473B2 (en) 2003-04-08 2008-03-04 Surgiquest, Incorporated Pneumoseal trocar arrangement
US8317815B2 (en) 2006-10-06 2012-11-27 Surgiquest, Inc. Visualization trocar
US7285112B2 (en) 2003-04-08 2007-10-23 Surgiquest, Incorporated Gas flow trocar arrangement
US20040210198A1 (en) 2003-04-18 2004-10-21 Life-Shield Products, Inc. Safety retractable type syringe
US20050116673A1 (en) 2003-04-18 2005-06-02 Rensselaer Polytechnic Institute Methods and systems for controlling the operation of a tool
US7311673B2 (en) 2003-04-24 2007-12-25 Acueity, Inc. Biopsy device
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
US6890308B2 (en) 2003-06-03 2005-05-10 Abul Bashar Mohammed Anwarul Islam Bone marrow biopsy needle
US7186257B2 (en) 2003-06-09 2007-03-06 Jun Hyun Kim Auxiliary apparatus for inserting a pin into a broken bone
US7494473B2 (en) 2003-07-30 2009-02-24 Intact Medical Corp. Electrical apparatus and system with improved tissue capture component
US6960164B2 (en) 2003-08-01 2005-11-01 Neosurg Technologies, Inc. Obturator tip for a trocar
US7615043B2 (en) 2003-08-20 2009-11-10 Boston Scientific Scimed, Inc. Medical device incorporating a polymer blend
US7137985B2 (en) 2003-09-24 2006-11-21 N Spine, Inc. Marking and guidance method and system for flexible fixation of a spine
WO2005030318A1 (en) 2003-09-25 2005-04-07 Nuvasive, Inc. Surgical access system and related methods
US7419472B2 (en) 2003-09-30 2008-09-02 Ethicon Endo-Surgery, Inc. Biopsy instrument with internal specimen collection mechanism
CN2664675Y (en) 2003-11-21 2004-12-22 中国人民解放军第三军医大学野战外科研究所 Incorporated breast bone transfusion device
US9408592B2 (en) 2003-12-23 2016-08-09 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US7513722B2 (en) 2003-12-30 2009-04-07 Greenberg Surgical Technologies, Llc Collet collar stop for a drill bit
CN1913833B (en) 2004-01-26 2010-06-09 维达保健公司 Manual interosseous device
US7815642B2 (en) 2004-01-26 2010-10-19 Vidacare Corporation Impact-driven intraosseous needle
US7402140B2 (en) 2004-02-12 2008-07-22 Sanarus Medical, Inc. Rotational core biopsy device with liquid cryogen adhesion probe
WO2005087449A1 (en) 2004-03-15 2005-09-22 Maxtech Manufacturing Inc. Rotary tool with improved connecting means for attachments thereto
WO2005107525A2 (en) 2004-04-22 2005-11-17 Children's Medical Center Corporation Medical procedure cart and method of customizing the same
WO2005112800A2 (en) 2004-05-17 2005-12-01 Tiax Llc Intraosseous infusion device
WO2005110259A1 (en) 2004-05-19 2005-11-24 Sintea Biotech S.P.A. Intravertebral widening device, injection device, and kit and method for kyphoplasty
US7934333B1 (en) 2004-05-21 2011-05-03 Michael Tuz Pistol concealment device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1659414A4 (en) 2004-06-30 2012-12-19 Panasonic Corp Capacitor deterioration judgment method
US7308985B2 (en) * 2004-07-14 2007-12-18 Scimed Life Systems, Inc. Packaging for a kit, and related methods of use
DE102004051913A1 (en) 2004-08-09 2006-02-23 Robert Bosch Gmbh Cordless Screwdriver
US20060043685A1 (en) 2004-08-25 2006-03-02 Burton Kozak Universal bit and tool holder for a linear-to-rotational motion converting device
US20060074345A1 (en) 2004-09-29 2006-04-06 Hibner John A Biopsy apparatus and method
SE0402394D0 (en) 2004-10-04 2004-10-04 Vibratech Ab Medical arrangement
US20060079774A1 (en) * 2004-10-08 2006-04-13 Wendell Anderson Microwave biopsy probe
US7938830B2 (en) 2004-10-15 2011-05-10 Baxano, Inc. Powered tissue modification devices and methods
US7329227B2 (en) * 2004-10-21 2008-02-12 Inter-V-Manan Forward-fired automatic tissue sampling apparatus with safety lock
US7331462B2 (en) 2004-10-26 2008-02-19 Alcon, Inc. Kit management system
US7828773B2 (en) 2005-07-11 2010-11-09 Covidien Ag Safety reset key and needle assembly
US8998848B2 (en) 2004-11-12 2015-04-07 Vidacare LLC Intraosseous device and methods for accessing bone marrow in the sternum and other target areas
US7424288B2 (en) 2004-11-22 2008-09-09 Searete Llc Call transfer to proximate devices
US20060111724A1 (en) 2004-11-24 2006-05-25 Yeung Research Bone harvesting drill bit for oral surgery
US20060122535A1 (en) 2004-12-08 2006-06-08 Wolfgang Daum Method and device to obtain percutaneous tissue samples
WO2006061514A1 (en) 2004-12-08 2006-06-15 Laurane Medical Perforating trocar
US7611474B2 (en) 2004-12-29 2009-11-03 Ethicon Endo-Surgery, Inc. Core sampling biopsy device with short coupled MRI-compatible driver
US20060144548A1 (en) 2004-12-30 2006-07-06 Beckman Andrew T Method of manufacturing a needle assembly for use with a biopsy device
US7249638B2 (en) 2005-01-07 2007-07-31 Black & Decker Inc. Impact wrench anvil and method of forming an impact wrench anvil
US20060173480A1 (en) 2005-01-31 2006-08-03 Yi Zhang Safety penetrating method and apparatus into body cavities, organs, or potential spaces
DE102005005007B3 (en) 2005-02-03 2006-09-07 Lts Lohmann Therapie-Systeme Ag Biopsy needle for histological examination of body tissue
DE102005005017A1 (en) 2005-02-03 2006-08-17 Roche Diagnostics Gmbh Electromechanical lancing device for obtaining liquid samples
US20060184063A1 (en) 2005-02-15 2006-08-17 Miller Michael E Single motor handheld biopsy device
US20060189940A1 (en) 2005-02-24 2006-08-24 Kirsch Andrew J Implant positioning system and method
DE102005000015A1 (en) 2005-02-25 2006-08-31 Hilti Ag tool holder
US20060237205A1 (en) 2005-04-21 2006-10-26 Eastway Fair Company Limited Mode selector mechanism for an impact driver
DE102005000097A1 (en) 2005-07-28 2007-02-01 Hilti Ag Impact tool holder
DE102005000168A1 (en) 2005-11-25 2007-05-31 Hilti Ag tool holder
US7510543B2 (en) 2005-12-28 2009-03-31 Smiths Medical Md, Inc. Removable sharps device for accessing a portal reservoir
US7565935B1 (en) 2006-03-06 2009-07-28 Phillips Robert E Powered tap driver with rotary control structure
US20070209957A1 (en) 2006-03-09 2007-09-13 Sdgi Holdings, Inc. Packaging system for medical devices
US9867646B2 (en) 2006-04-07 2018-01-16 Gamal Baroud Integrated cement delivery system for bone augmentation procedures and methods
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
EP3167813B1 (en) 2006-09-12 2019-11-13 Teleflex Medical Devices S.à.r.l. Bone marrow aspiration devices
EP2068743B1 (en) * 2006-09-12 2017-03-15 Vidacare LLC Medical procedures trays, kits and related methods
US20080072719A1 (en) 2006-09-27 2008-03-27 Burton Kozak Non-ferrous bit for use with a magnetic chuck
US7980321B2 (en) 2006-10-13 2011-07-19 Snap-On Incorporated Anvil for a power tool
US8974410B2 (en) 2006-10-30 2015-03-10 Vidacare LLC Apparatus and methods to communicate fluids and/or support intraosseous devices
WO2008077080A2 (en) 2006-12-18 2008-06-26 Surgiquest, Incorporated System for surgical insufflation and gas recirculation
US8221431B2 (en) 2006-12-18 2012-07-17 Greatbatch Medical S.A. Calibrated mechanical orthopedic driver with wear-compensated torque-limiting mechanism
IL180469A0 (en) 2006-12-31 2007-06-03 Gil Shetrit Vascular access system and method
JP4576587B2 (en) 2007-01-23 2010-11-10 株式会社Jimro Bone marrow drill
CA2714069A1 (en) 2007-02-07 2008-08-14 Massachusetts Institute Of Technology Methods and devices for sensing tissues and tissue compartments
US9468396B2 (en) 2007-03-19 2016-10-18 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
EP2134253B1 (en) 2007-03-19 2022-01-26 University Of Virginia Patent Foundation Access needle pressure sensor device
US8066717B2 (en) 2007-03-19 2011-11-29 Restoration Robotics, Inc. Device and method for harvesting and implanting follicular units
WO2008124463A2 (en) 2007-04-04 2008-10-16 Vidacare Corporation Powered drivers, intraosseous devices and methods to access bone marrow
US20080262383A1 (en) 2007-04-17 2008-10-23 Needletech Products, Inc. Needle assembly with separable handle
CN101720243A (en) 2007-05-17 2010-06-02 维达保健公司 Monitor patients and with the method and apparatus of treat with intraosseous fluids
JP2008302434A (en) 2007-06-05 2008-12-18 Hitachi Koki Co Ltd Power tool
US7798331B2 (en) 2007-08-20 2010-09-21 Suros Surgical Systems, Inc. Tissue collection tray
JP4405572B1 (en) 2007-09-17 2010-01-27 日本特殊陶業株式会社 Spark plug
US8192353B2 (en) 2007-10-05 2012-06-05 Tyco Healthcare Group Lp Visual obturator
WO2009066972A1 (en) 2007-11-20 2009-05-28 Innovamédica S.A.P.I. De C.V. Electronic syringe with safety system for spinal injections
AR070764A1 (en) 2007-12-07 2010-05-05 Pyng Medical Corp APPLIANCES AND METHODS TO ENTER OSEOS PORTALS
US8668398B2 (en) * 2008-03-26 2014-03-11 Andrea ROSENGARD Hair coloration applicator
US8814935B2 (en) 2008-03-31 2014-08-26 The Lonnie and Shannon Paulos Trust Interference screw driver assembly and method of use
US9017333B2 (en) 2008-04-17 2015-04-28 Warsaw Orthopedic, Inc. Surgical tool
FR2931451B1 (en) 2008-05-22 2010-12-17 Fmc Technologies Sa CONTROL DEVICE FOR SYSTEM FOR LOADING AND / OR UNLOADING FLUIDS
US8109183B2 (en) 2008-06-06 2012-02-07 Black & Decker Inc. Impact resistant tool bit and tool bit holder
GB0812555D0 (en) 2008-07-10 2008-08-13 Depuy Int Ltd Container and system of containers of surgical instruments
MX2008011713A (en) 2008-09-12 2010-03-12 Hector De Jesus Velez Rivera Epidural space locating device.
US8974569B2 (en) 2008-10-10 2015-03-10 Paul A. Matula Multi-flow filtration system
KR101649505B1 (en) 2008-10-10 2016-08-19 서지퀘스트, 인코포레이티드 System and method for improved gas recirculation in surgical trocars with pneumatic sealing
WO2010042914A2 (en) 2008-10-10 2010-04-15 Surgiquest, Inc. Multi-flow filtration system
ATE525023T1 (en) 2009-02-06 2011-10-15 Roberto Zambelli BONE BIOPSY APPARATUS
WO2010098905A1 (en) 2009-02-25 2010-09-02 Joint Product Solutions, Llc Surgical retention port and method of use
CA3221305A1 (en) 2009-08-19 2011-02-24 Medline Industries, Inc. Systems, methods, and devices for facilitating access to target anatomical sites or environments
US8814807B2 (en) 2009-08-19 2014-08-26 Mirador Biomedical Spinal canal access and probe positioning, devices and methods
US10463838B2 (en) 2009-08-19 2019-11-05 Medline Industries, Inc Vascular access methods and devices
EP2954870B1 (en) 2009-09-18 2018-04-25 Biomet C.V. Disposable orthopaedic surgery kit and components
WO2011070593A1 (en) 2009-12-11 2011-06-16 Secretary, Department Of Biotechnology Device for vascular access
WO2011085194A1 (en) 2010-01-07 2011-07-14 Black & Decker Inc. Power screwdriver having rotary input control
US20150173818A1 (en) 2010-01-20 2015-06-25 Gamal Baroud Minimally invasive method and applications for injectible materials
WO2011123703A1 (en) 2010-03-31 2011-10-06 Smart Medical Devices, Inc. Depth controllable and measurable medical driver devices
US9301690B2 (en) 2010-04-22 2016-04-05 University Of Houston System Device, system, and method for a stress sensing medical needle
WO2012044410A2 (en) 2010-09-20 2012-04-05 Surgiquest, Inc. Multi-flow filtration system
FR2972176B1 (en) 2011-03-04 2014-03-07 Messier Bugatti HYDRAULIC BRAKING ARCHITECTURES FOR AIRCRAFT FOR BRAKING AT LEAST ONE WHEEL OF THE AIRCRAFT.
KR20120134169A (en) 2011-06-01 2012-12-12 삼성전자주식회사 Voltage-temperature sensor and system including the same
GB2492091B (en) 2011-06-21 2018-04-04 Seatriever International Holdings Ltd An illumination device for a balloon
US8720097B2 (en) 2011-09-11 2014-05-13 Jay S Derman Trigger lock
US8584853B2 (en) 2012-02-16 2013-11-19 Biomedical Enterprises, Inc. Method and apparatus for an orthopedic fixation system
CN104219998A (en) 2012-03-30 2014-12-17 皇家飞利浦有限公司 Medical needle
GB2517363B (en) 2012-06-05 2016-02-24 Mayank Goyal Systems and methods for enhancing preparation and completion of surgical and medical procedures
US9901398B2 (en) 2012-06-29 2018-02-27 Covidien Lp Microwave antenna probes
WO2014097301A1 (en) 2012-12-22 2014-06-26 Omeq Medical Ltd. Positioning and tissue sensing devices and methods
US9615816B2 (en) 2013-03-15 2017-04-11 Vidacare LLC Drivers and drive systems
US20140311302A1 (en) 2013-04-17 2014-10-23 Vessel Industrial Co., Ltd. Attachment for rotating tool
JP6132663B2 (en) 2013-06-03 2017-05-24 レンゴー株式会社 Corrugated cardboard box
US9370372B2 (en) 2013-09-04 2016-06-21 Mcginley Engineered Solutions, Llc Drill bit penetration measurement systems and methods
CN106572845B (en) 2014-02-07 2020-04-21 泰利福医疗工具有限公司 Auxiliary device for taking a biological sample from an intraosseous device, and related kit and method
CN110200663B (en) 2014-02-17 2022-04-29 泰利福生命科学有限公司 Power driver actuated by force on a drive shaft and related kits, components, and methods
EP3168005A1 (en) 2015-08-03 2017-05-17 Chervon (HK) Limited Torque output tool and torque output assembly
TWM522105U (en) 2016-03-15 2016-05-21 wei-jie Zhuang Torque socket with torque adjustability
US10736649B2 (en) 2016-08-25 2020-08-11 Ethicon Llc Electrical and thermal connections for ultrasonic transducer

Patent Citations (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US389445A (en) * 1888-09-11 William crede
US2317648A (en) * 1941-07-08 1943-04-27 Ivar E Siqveland Process and apparatus for producing intraosseous anesthesia
US2419045A (en) * 1947-01-04 1947-04-15 Charles C Whittaker Spring-driven rotatable surgical cutter with hand pressure speed control
US2773501A (en) * 1955-01-26 1956-12-11 Harold S Young Drill element for effecting intraosseous fluid injections and the like
US3120845A (en) * 1961-02-20 1964-02-11 David B Horner Self-powered surgical drill
US3173417A (en) * 1961-06-15 1965-03-16 David B Horner Self-powered sterilizable surgical drill
US3893445A (en) * 1974-01-09 1975-07-08 Becton Dickinson Co Bone marrow biopsy instrument
US4258722A (en) * 1978-12-15 1981-03-31 Ferris Manufacturing Corp. Disposable biopsy needle, particularly for bone marrow samplings
US4262676A (en) * 1979-08-24 1981-04-21 Khosrow Jamshidi Biopsy needle having integral stylet locking device
US4381777A (en) * 1980-01-14 1983-05-03 Micro-Mega S.A. Syringe with oscillating needle
US5279306B1 (en) * 1981-03-16 1998-06-02 Creative Res & Mfg Biopsy needle
US5279306A (en) * 1981-03-16 1994-01-18 Creative Research And Manufacturing Biopsy needle
US4469109A (en) * 1981-12-24 1984-09-04 Creative Research And Manufacturing Inc. Bone marrow aspiration needle
US4655226A (en) * 1983-12-16 1987-04-07 Southland Instruments, Inc. Disposable biopsy needle unit
US4723945A (en) * 1984-05-03 1988-02-09 Bunder Glas Gmbh Hypodermic syringe
US4692073A (en) * 1985-02-25 1987-09-08 Martindell J Richard Handle adapter and chuck apparatus for power bits
US4787893A (en) * 1985-05-09 1988-11-29 Alain Villette Instrument for injecting biocompatible products through bone tissue
US4867158A (en) * 1987-07-20 1989-09-19 Sugg Winfred L Hand held battery powered bone awl
US5431655A (en) * 1988-10-24 1995-07-11 Cook Incorporated Intraosseous needle
US4919146A (en) * 1988-10-25 1990-04-24 Medrad, Inc. Biopsy device
US5139500A (en) * 1989-05-08 1992-08-18 Schwartz Nathan H Bone attachment system
US4969870A (en) * 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
US5195985A (en) * 1990-05-25 1993-03-23 Hall John E Syringe having a retractable needle
US5122114A (en) * 1991-02-01 1992-06-16 Board Of Regents, University Of Texas System Method of using intramedullary catheter
US5451210A (en) * 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
US5207697A (en) * 1991-06-27 1993-05-04 Stryker Corporation Battery powered surgical handpiece
US5324300A (en) * 1991-10-25 1994-06-28 Elias Elias G Device for the controlled excision of tissue from a living body
US6228088B1 (en) * 1992-02-01 2001-05-08 Board Of Regents, The University Of Texas System Combination drill bit and intrametullary catheter and method of using same
US5332398A (en) * 1992-02-01 1994-07-26 Board Of Regents, The University Of Texas System Intramedullary catheter
US5810826A (en) * 1992-03-23 1998-09-22 Radi Medical Systems Ab Puncture instrument
US5423824A (en) * 1992-03-23 1995-06-13 Radi Medical Systems Ab Method of accessing hard tissue
US5257632A (en) * 1992-09-09 1993-11-02 Symbiosis Corporation Coaxial bone marrow biopsy coring and aspirating needle assembly and method of use thereof
US5368046A (en) * 1992-09-09 1994-11-29 Symbiosis Corporation Bone marrow needle assembly
US6523698B1 (en) * 1993-07-12 2003-02-25 Baxter International, Inc. Bone marrow kit
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
US5591188A (en) * 1994-04-12 1997-01-07 Wais-Med Lmt, A Subsidiary Company Of Teic Technion Enterpreneurial Incubator Ltd. Surgical instrument for impact insertion of an intraosseous trocar-needle
US5554154A (en) * 1995-03-03 1996-09-10 Rosenberg; Norman Intra-osseous needle drill
US5928238A (en) * 1995-03-15 1999-07-27 Osteotech, Inc. Bone dowel cutter
US5762639A (en) * 1995-04-07 1998-06-09 Gibbs; David E. Device for targeted, catherized delivery of medications
US5586847A (en) * 1995-06-06 1996-12-24 Mattern, Jr.; Charles J. Power tool adapter
US20030032939A1 (en) * 1995-06-06 2003-02-13 David Gibbs Device for targeted, catherized delivery of medications
US6468248B2 (en) * 1995-06-06 2002-10-22 David Gibbs Device for targeted, catherized delivery of medications
US6217561B1 (en) * 1995-06-06 2001-04-17 David Gibbs Medication injection device and method
US6325806B1 (en) * 1995-10-30 2001-12-04 Biomedical Enterprises, Inc. Materials collection system and uses thereof
US5817052A (en) * 1995-12-26 1998-10-06 Pyng Medical Corp. Apparatus for intraosseous infusion or aspiration
US6096042A (en) * 1996-01-04 2000-08-01 Herbert; Timothy James Driver
US5927976A (en) * 1996-05-10 1999-07-27 Cyberdent, Inc. Medication injection device and method
US5980545A (en) * 1996-05-13 1999-11-09 United States Surgical Corporation Coring device and method
US5779708A (en) * 1996-08-15 1998-07-14 Cyberdent, Inc. Intraosseous drug delivery device and method
US6283970B1 (en) * 1997-03-20 2001-09-04 Philipp Lubinus Cutting tool for cleaning out the femur medullary space and artificial hip to be inserted into this space
US5924864A (en) * 1997-04-18 1999-07-20 Kaltenbach & Voigt Gmbh Handpiece for medical purposes, in particular for a medical or dental treatment device, preferably for a cutting treatment of a dental root canal
US20030078586A1 (en) * 1997-07-01 2003-04-24 Shapira Ira L. Method and apparatus for extracting bone marrow
US6358252B1 (en) * 1997-07-01 2002-03-19 Ira L. Shapira Apparatus for extracting bone marrow
US20020029007A1 (en) * 1997-09-19 2002-03-07 Bryan Graham W. Biopsy apparatus and method
US5941706A (en) * 1997-10-20 1999-08-24 Ura; Robert S. Variable depth medical drill and method of making the same
US6315737B1 (en) * 1998-01-02 2001-11-13 Biopsy Needle Limited Partnership Biopsy needle for a biopsy instrument
US6183442B1 (en) * 1998-03-02 2001-02-06 Board Of Regents Of The University Of Texas System Tissue penetrating device and methods for using same
US6247928B1 (en) * 1998-04-09 2001-06-19 Moshe Meller Disposable anesthesia delivery system
US6582399B1 (en) * 1998-04-27 2003-06-24 Computer Controlled Syringe Inc. Syringe with detachable syringe barrel
US6761726B1 (en) * 1998-05-15 2004-07-13 Pyng Medical Corp. Method and apparatus for the intraosseous introduction of a device such as an infusion tube
US6110129A (en) * 1998-07-13 2000-08-29 Medical Device Technologies, Inc. Biopsy needle and surgical instrument
US6033369A (en) * 1998-09-23 2000-03-07 Goldenberg; Alec Disposable handle and needle assembly
US6135769A (en) * 1998-11-20 2000-10-24 Kwan; Danny Pak-Nam Intraosseous injection system
US6210376B1 (en) * 1999-04-08 2001-04-03 New York University Cannulated delivery pin
US6221029B1 (en) * 1999-05-13 2001-04-24 Stryker Corporation Universal biopsy system
US6328744B1 (en) * 1999-06-04 2001-12-11 American Medical Systems, Inc. Bone suturing device
US6547561B2 (en) * 1999-06-09 2003-04-15 Tulsa Dental Products Inc. Disposable anesthesia delivery system with shortened outer sleeve and inner hollow drill
US6273715B1 (en) * 1999-06-09 2001-08-14 X-Tip Technologies, Llc Disposable anesthesia delivery system with shortened outer sleeve and inner hollow drill
US6287114B1 (en) * 1999-06-09 2001-09-11 X-Tip Technologies, Llc Disposable anesthesia delivery system with shortened outer sleeve and inner solid drill
US6257351B1 (en) * 1999-06-29 2001-07-10 Microaire Surgical Instruments, Inc. Powered surgical instrument having locking systems and a clutch mechanism
US20030191414A1 (en) * 1999-10-19 2003-10-09 Kyphon Inc. Hand-held instruments that access interior body regions
US6478751B1 (en) * 2000-04-18 2002-11-12 Allegiance Corporation Bone marrow aspiration needle
US6302852B1 (en) * 2000-04-25 2001-10-16 Manan Medical Products, Inc. Bone marrow biopsy device
US6312394B1 (en) * 2000-04-25 2001-11-06 Manan Medical Products, Inc. Bone marrow biopsy device
US20030009132A1 (en) * 2001-04-13 2003-01-09 Tricardia Llc Syringe system
US20030225411A1 (en) * 2002-05-31 2003-12-04 Vidacare Corporation Apparatus and method to access bone marrow
US6875219B2 (en) * 2003-02-14 2005-04-05 Yves P. Arramon Bone access system

Cited By (195)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060247552A1 (en) * 2001-08-09 2006-11-02 Jimro Co., Ltd. Bone marrow harvesting set and bone marrow harvesting needle
US20040215102A1 (en) * 2001-08-09 2004-10-28 Susumu Ikehara Marrow fluid sampling set and marrow needle
US9439667B2 (en) 2002-05-31 2016-09-13 Vidacare LLC Apparatus and methods to install, support and/or monitor performance of intraosseous devices
US9451968B2 (en) 2002-05-31 2016-09-27 Vidacare LLC Powered drivers, intraosseous devices and methods to access bone marrow
US11324521B2 (en) 2002-05-31 2022-05-10 Teleflex Life Sciences Limited Apparatus and method to access bone marrow
US9072543B2 (en) 2002-05-31 2015-07-07 Vidacare LLC Vascular access kits and methods
US9078637B2 (en) 2002-05-31 2015-07-14 Vidacare LLC Apparatus and methods to harvest bone and bone marrow
US9295487B2 (en) 2002-05-31 2016-03-29 Vidacare LLC Apparatus and method to inject fluids into bone marrow and other target sites
US11298202B2 (en) 2002-05-31 2022-04-12 Teleflex Life Sciences Limited Biopsy devices and related methods
US9314228B2 (en) 2002-05-31 2016-04-19 Vidacare LLC Apparatus and method for accessing the bone marrow
US11291472B2 (en) 2002-05-31 2022-04-05 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US11266441B2 (en) 2002-05-31 2022-03-08 Teleflex Life Sciences Limited Penetrator assembly for accessing bone marrow
US20080045861A1 (en) * 2002-05-31 2008-02-21 Miller Larry J Medical Procedures Trays And Related Methods
US11234683B2 (en) 2002-05-31 2022-02-01 Teleflex Life Sciences Limited Assembly for coupling powered driver with intraosseous device
US11103282B1 (en) 2002-05-31 2021-08-31 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US11103281B2 (en) 2002-05-31 2021-08-31 Teleflex Life Sciences Limited Apparatus and methods to install, support and/or monitor performance of intraosseous devices
US11065382B2 (en) 2002-05-31 2021-07-20 Teleflex Life Sciences Limited Apparatus to inject fluids into bone marrow and other target sites
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US10973532B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US9314270B2 (en) 2002-05-31 2016-04-19 Vidacare LLC Apparatus and method to access bone marrow
US10893875B2 (en) 2002-05-31 2021-01-19 Teleflex Life Sciences Limited Apparatus to access bone marrow
US10806491B2 (en) 2002-05-31 2020-10-20 Teleflex Life Sciences Limited Vascular access kits and methods
US10595896B2 (en) 2002-05-31 2020-03-24 Teleflex Life Sciences Limited Apparatus for accessing bone marrow including depth control mechanism
US10512474B2 (en) 2002-05-31 2019-12-24 Teleflex Medical Devices S.À R.L. Powered drivers, intraosseous devices and methods to access bone marrow
US7670328B2 (en) 2002-05-31 2010-03-02 Vidacare Corporation Apparatus and method to provide emergency access to bone marrow
US10492830B2 (en) 2002-05-31 2019-12-03 Teleflex Medical Devices S.À R.L. Penetrator assembly for accessing bone marrow
US7699850B2 (en) 2002-05-31 2010-04-20 Vidacare Corporation Apparatus and method to access bone marrow
US7811260B2 (en) 2002-05-31 2010-10-12 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US8715287B2 (en) 2002-05-31 2014-05-06 Vidacare Corporation Apparatus and method to provide emergency access to bone marrow
US7850620B2 (en) 2002-05-31 2010-12-14 Vidacare Corporation Biopsy devices and related methods
US20110082387A1 (en) * 2002-05-31 2011-04-07 Miller Larry J Biopsy Devices and Related Methods
US10456149B2 (en) 2002-05-31 2019-10-29 Teleflex Medical Devices S.À R.L. Apparatus and method to access bone marrow
US10413282B2 (en) 2002-05-31 2019-09-17 Teleflex Medical Devices S.Àr.L. Apparatus and methods to harvest bone and bone marrow
US7951089B2 (en) 2002-05-31 2011-05-31 Vidacare Corporation Apparatus and methods to harvest bone and bone marrow
US10245010B2 (en) 2002-05-31 2019-04-02 Teleflex Medical Devices S.A.R.L Assembly for coupling powered driver with intraosseous device
US8690791B2 (en) 2002-05-31 2014-04-08 Vidacare Corporation Apparatus and method to access the bone marrow
US8684978B2 (en) 2002-05-31 2014-04-01 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US10166332B2 (en) 2002-05-31 2019-01-01 Teleflex Medical Devices S.À R.L. Apparatus to inject fluids into bone marrow and other target sites
US9393031B2 (en) 2002-05-31 2016-07-19 Vidacare LLC Apparatus and method to provide emergency access to bone marrow
US8876826B2 (en) 2002-05-31 2014-11-04 Vidacare Corporation Apparatus and method to access bone marrow
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
US8656929B2 (en) 2002-05-31 2014-02-25 Vidacare Corporation Medical procedures trays and related methods
US10016217B2 (en) 2002-05-31 2018-07-10 Teleflex Medical Devices S.À.R.L. Apparatus and methods to install, support and/or monitor performance of intraosseous devices
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US9872703B2 (en) 2002-05-31 2018-01-23 Teleflex Medical Devices S.Àr.L. Vascular access kits and methods
US8992535B2 (en) 2002-05-31 2015-03-31 Vidacare LLC Apparatus and method to provide emergency access to bone marrow
US8142365B2 (en) 2002-05-31 2012-03-27 Vidacare Corporation Apparatus and method for accessing the bone marrow of the sternum
US9717847B2 (en) 2002-05-31 2017-08-01 Teleflex Medical Devices S.Àr.L. Apparatus and method to inject fluids into bone marrow and other target sites
US11337728B2 (en) 2002-05-31 2022-05-24 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US8308693B2 (en) 2002-05-31 2012-11-13 Vidacare Corporation Bone penetrating needle with angled ports
US9717564B2 (en) * 2002-05-31 2017-08-01 Teleflex Medical Devices S.À R.L. Biopsy devices and related methods
US9545243B2 (en) 2002-05-31 2017-01-17 Vidacare LLC Bone marrow aspiration devices and related methods
US8038664B2 (en) 2002-05-31 2011-10-18 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US8480632B2 (en) 2002-05-31 2013-07-09 Vidacare Corporation Cartridge apparatus for injecting fluids into bone
US8506568B2 (en) 2002-05-31 2013-08-13 Vidacare Corporation Apparatus and method to access bone marrow
US8043253B2 (en) 2002-06-04 2011-10-25 Daniel Kraft Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US8002733B2 (en) 2002-06-04 2011-08-23 Daniel Kraft Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US20030225364A1 (en) * 2002-06-04 2003-12-04 Stanford, Office Of Technology Licensing Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US8109919B2 (en) 2002-06-04 2012-02-07 Daniel Kraft Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US9895512B2 (en) 2002-06-04 2018-02-20 The Board Of Trustees Of The Leland Stanford Junior University Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US20070135759A1 (en) * 2002-06-04 2007-06-14 Daniel Kraft Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US20070276352A1 (en) * 2002-06-04 2007-11-29 Stemcor Systems, Inc. Removable device and method for tissue disruption
US9131925B2 (en) 2002-06-04 2015-09-15 The Board Of Trustees Of The Leland Stanford Junior University Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US20070197996A1 (en) * 2002-06-04 2007-08-23 Daniel Kraft Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US7462181B2 (en) 2002-06-04 2008-12-09 Stanford Office Of Technology Licensing Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US8562542B2 (en) 2003-03-28 2013-10-22 Depuy Mitek, Llc Tissue collection device and methods
US10052111B2 (en) 2003-05-30 2018-08-21 Teleflex Medical Devices S.À R.L. Powered driver
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
US8870788B2 (en) 2003-09-11 2014-10-28 Depuy Mitek, Llc Tissue extraction and collection device
US8585610B2 (en) 2003-09-11 2013-11-19 Depuy Mitek, Llc Tissue extraction and maceration device
US8034003B2 (en) 2003-09-11 2011-10-11 Depuy Mitek, Inc. Tissue extraction and collection device
US7998086B2 (en) 2003-09-11 2011-08-16 Depuy Mitek, Inc. Tissue extraction and maceration device
FR2861572A1 (en) * 2003-10-30 2005-05-06 Patrice Richard DEVICE FOR TAKING AND / OR INJECTING BONE MARROW AND SYSTEM COMPRISING SUCH A DEVICE
US8870872B2 (en) 2004-01-26 2014-10-28 Vidacare Corporation Impact-driven intraosseous needle
US7815642B2 (en) 2004-01-26 2010-10-19 Vidacare Corporation Impact-driven intraosseous needle
US9433400B2 (en) 2004-01-26 2016-09-06 Vidacare LLC Manual intraosseous device
US8246584B2 (en) 2004-07-01 2012-08-21 W&H Dentalwerk Bürmoos GmbH Injection systems
US20060106363A1 (en) * 2004-07-01 2006-05-18 Aravena Ines M Injection systems
US7588559B2 (en) 2004-07-01 2009-09-15 W&H Dentalwerk Bürmoos GmbH Injection systems
US20100057005A1 (en) * 2004-07-01 2010-03-04 W&H Dentalwerk Burmoos Gmbh Injection systems
US20070270712A1 (en) * 2004-10-04 2007-11-22 Vibratech Ab Arrangement for Taking a Sample of Bone Marrow and/or Evacuating the Sinuses
WO2006050087A3 (en) * 2004-10-29 2009-04-09 Depuy Products Inc Coordinate instrument set
US9113954B2 (en) 2004-10-29 2015-08-25 DePuy Synthes Products, Inc. Coordinate instrument set
US20060211953A1 (en) * 2004-10-29 2006-09-21 Zannis Anthony D Coordinate instrument set
US8419683B2 (en) 2004-11-12 2013-04-16 Vidacare Corporation Intraosseous device and methods for accessing bone marrow in the sternum and other target areas
US8998848B2 (en) 2004-11-12 2015-04-07 Vidacare LLC Intraosseous device and methods for accessing bone marrow in the sternum and other target areas
US20180085115A1 (en) * 2006-01-27 2018-03-29 Endoevolution, Llc Apparatus and method for tissue closure
US11033262B2 (en) * 2006-01-27 2021-06-15 Intuitive Surgical Operations, Inc. Apparatus and method for tissue closure
WO2008002961A2 (en) * 2006-06-29 2008-01-03 Vidacare Corporation Apparatus and methods to harvest bone and bone marrow
WO2008002961A3 (en) * 2006-06-29 2008-05-15 Vidacare Corp Apparatus and methods to harvest bone and bone marrow
US20080039884A1 (en) * 2006-08-10 2008-02-14 Nohilly Martin J Morcellator with detachable handle
WO2008021716A3 (en) * 2006-08-10 2008-10-02 Ethicon Inc Morcellator with detachable handle
KR101399298B1 (en) 2006-08-10 2014-05-27 에디컨인코포레이티드 Morcellator with detachable handle
US8100928B2 (en) 2006-08-10 2012-01-24 Ethicon, Inc. Morcellator with detachable handle
WO2008021716A2 (en) * 2006-08-10 2008-02-21 Ethicon, Inc. Morcellator with detachable handle
AU2007284244B2 (en) * 2006-08-10 2013-01-31 Ethicon, Inc. Morcellator with detachable handle
WO2008033873A3 (en) * 2006-09-12 2008-07-17 Vidacare Corp Medical procedures trays and related methods
US11426249B2 (en) 2006-09-12 2022-08-30 Teleflex Life Sciences Limited Vertebral access system and methods
US9510910B2 (en) 2006-09-12 2016-12-06 Vidacare LLC Medical procedures trays and related methods
WO2008033872A2 (en) 2006-09-12 2008-03-20 Vidacare Corporation Biopsy devices and related methods
EP2073728A2 (en) * 2006-09-12 2009-07-01 Vidacare Corporation Biopsy devices and related methods
EP2073728A4 (en) * 2006-09-12 2011-04-20 Vidacare Corp Biopsy devices and related methods
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
EP3659520A3 (en) * 2006-09-12 2020-07-29 Teleflex Medical Devices S.à.r.l. Bone marrow aspiration devices
US8974410B2 (en) 2006-10-30 2015-03-10 Vidacare LLC Apparatus and methods to communicate fluids and/or support intraosseous devices
US10258783B2 (en) 2006-10-30 2019-04-16 Teleflex Medical Devices S.À R.L. Apparatus and methods to communicate fluids and/or support intraosseous devices
US11583668B2 (en) 2006-10-30 2023-02-21 Teleflex Life Sciences Limited Apparatus and methods to communicate fluids and/or support intraosseous devices
US20080109007A1 (en) * 2006-11-02 2008-05-08 Stryker Trauma Gmbh Implantation device, applicator and sonotrode
US11771439B2 (en) 2007-04-04 2023-10-03 Teleflex Life Sciences Limited Powered driver
US20090149774A1 (en) * 2007-12-06 2009-06-11 Ebi, L.P. bone marrow aspiration needle
US8617085B2 (en) * 2008-08-14 2013-12-31 Antonio Moran, JR. Bone tissue extracting device and method
US20110184312A1 (en) * 2008-08-14 2011-07-28 Moran Jr Antonio Bone Tissue Extracting Device and Method
US8674656B2 (en) 2008-11-14 2014-03-18 Panasonic Corporation Carrying case and syringe system with same
CN102202703A (en) * 2008-11-14 2011-09-28 松下电器产业株式会社 Carrying case and syringe system with same
US8398602B2 (en) 2008-11-14 2013-03-19 Panasonic Corporation Carrying case and syringe system with same
US20110218502A1 (en) * 2008-11-14 2011-09-08 Toshiaki Iio Carrying case and syringe system with same
US20110082425A1 (en) * 2009-10-02 2011-04-07 Howmedica Osteonics Corp. Bone Marrow Aspirator And Methods Therefor
US9078638B2 (en) 2009-10-02 2015-07-14 Howmedica Osteonics Corp. Bone marrow aspirator and methods therefor
US10857284B2 (en) 2010-02-02 2020-12-08 Teleflex Life Sciences Limited Intraosseous-needle stabilizer and methods
US9839740B2 (en) 2010-02-02 2017-12-12 Teleflex Medical Devices S.À R.L Intraosseous-needle stabilizer and methods
US20110264129A1 (en) * 2010-03-31 2011-10-27 James Alistair Holdgate Surgical instrument
US8652156B2 (en) * 2010-03-31 2014-02-18 Gyrus Medical Limited Surgical instrument
WO2012007812A1 (en) * 2010-07-15 2012-01-19 Kebomed Ag Laparoscopic morcellator
US9144432B2 (en) 2010-10-05 2015-09-29 Trokamed Gmbh Medical instrument
EP2438867A3 (en) * 2010-10-05 2012-05-02 Trokamed GmbH Medical instrument
US20230181176A1 (en) * 2011-01-28 2023-06-15 The General Hospital Corporation Apparatus and method for tissue biopsy
US9173679B2 (en) 2011-04-11 2015-11-03 Waismed Ltd. Intraosseous device for inserting a cannula into a bone
US9451983B2 (en) * 2011-04-19 2016-09-27 Ao Technology Ag Cannula and kit for evaluation and preparation of bone tissue
US20140031794A1 (en) * 2011-04-19 2014-01-30 Ao Technology Ag Cannula and kit for evaluation and preparation of bone tissue
US11771462B2 (en) 2011-07-11 2023-10-03 Teleflex Life Sciences Limited Sternal locators and associated systems and methods
US9730729B2 (en) 2011-07-11 2017-08-15 Teleflex Medical Devices S.A R.L. Sternal locators and associated systems and methods
US10052109B2 (en) 2012-07-12 2018-08-21 DePuy Synthes Products, Inc. Saw, a saw blade, a connection mechanism and associated methods
US11109871B2 (en) 2012-07-12 2021-09-07 DePuy Synthes Products, Inc. Saw, a saw blade, a connection mechanism and associated methods
US20140144663A1 (en) * 2012-11-28 2014-05-29 Robert Bosch Gmbh Portable power tool
US9908234B2 (en) * 2012-11-28 2018-03-06 Robert Bosch Gmbh Portable power tool
CN103846884A (en) * 2012-11-28 2014-06-11 罗伯特·博世有限公司 Portable power tool
US9788774B2 (en) 2013-03-12 2017-10-17 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US20150032067A1 (en) * 2013-03-12 2015-01-29 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US10478109B2 (en) 2013-03-12 2019-11-19 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US9788775B2 (en) * 2013-03-12 2017-10-17 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US11439332B2 (en) 2013-03-12 2022-09-13 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US11806042B2 (en) 2013-07-01 2023-11-07 Merit Medical Systems, Inc. Perforating trocar
US10653444B2 (en) 2013-07-01 2020-05-19 Merit Medical Systems, Inc. Perforating trocar
US9770425B2 (en) 2014-10-09 2017-09-26 Aperture Medical Technology Llc Implantable bone marrow access apparatus
US10136878B2 (en) 2015-12-24 2018-11-27 Waismed Ltd. Automatic device and kit for inserting a cannula to a predetermined depth within a bone, irrespective of the thickness of the tissue above the bone
US11006933B2 (en) 2015-12-24 2021-05-18 Waismed Ltd. Device and method for inserting a cannula to a predetermined depth within a bone, irrespective of the thickness of the tissue above the bone
US11672514B2 (en) 2016-02-01 2023-06-13 RegenMed Systems, Inc. Cannula for tissue disruption
US11389141B2 (en) 2016-02-01 2022-07-19 RegenMed Systems, Inc. Cannula for tissue disruption
US20200229932A1 (en) * 2016-05-26 2020-07-23 Dmitry Arbuck Methods and tools for treating bone pain
WO2018006045A1 (en) * 2016-06-30 2018-01-04 Actuated Medical, Inc. Medical device for delivery and/or extraction of material
US20180028212A1 (en) * 2016-07-28 2018-02-01 Covidien Lp Reciprocating rotary surgical cutting device and system for tissue resecting, and method for its use
US11172954B2 (en) 2016-07-28 2021-11-16 Covidien Lp Reciprocating rotary surgical cutting device and system for tissue resecting, and method for its use
US10299819B2 (en) * 2016-07-28 2019-05-28 Covidien Lp Reciprocating rotary surgical cutting device and system for tissue resecting, and method for its use
US11103223B2 (en) 2016-10-05 2021-08-31 Aperture Medical Technology Llc Bone marrow access apparatus
US10448933B2 (en) 2016-10-05 2019-10-22 Aperture Medical Technology Llc Bone marrow access system
US11849926B2 (en) 2016-10-05 2023-12-26 Aperture Medical Technology Llc Bone marrow access apparatus
US20180092632A1 (en) * 2016-10-05 2018-04-05 Aperture Medical Technology Llc Bone marrow access apparatus
US10517576B2 (en) * 2016-10-05 2019-12-31 Aperture Medical Technology Llc Bone marrow access apparatus
US11883071B2 (en) 2016-10-27 2024-01-30 C. R. Bard, Inc. Intraosseous access device
US11826071B2 (en) 2016-11-23 2023-11-28 Corit Medical, Llc Apparatus and methods for tissue reduction
US10849645B2 (en) * 2016-11-23 2020-12-01 Corit Llc Apparatus and methods for tissue reduction
US20180140319A1 (en) * 2016-11-23 2018-05-24 Iyad Saidi Apparatus and methods for tissue reduction
US11484341B2 (en) 2017-03-07 2022-11-01 Piper Access, Llc Safety shields for elongated instruments and related systems and methods
WO2018165334A1 (en) * 2017-03-07 2018-09-13 Piper Access, Llc. Safety shields for elongated instruments and related systems and methods
US11013901B2 (en) 2017-03-10 2021-05-25 Piper Access, Llc Securement devices, systems, and methods
US11364583B2 (en) 2017-03-29 2022-06-21 Michael Paul Hill Center point drill and center point drill attachment
US10576594B2 (en) * 2017-03-29 2020-03-03 Michael Paul Hill Center point drill and center point drill attachment
US11701257B2 (en) 2017-04-09 2023-07-18 Sanoculis Ltd. Device and method for creating a channel in soft tissue
US11583442B2 (en) 2017-04-09 2023-02-21 Sanoculis Ltd. Device and method for creating a channel in soft tissue
US11357515B2 (en) 2017-09-09 2022-06-14 June Access Ip, Llc Intraosseous device having retractable motor/stylet assembly and automatic stylet point cover upon retraction operation
WO2019051343A1 (en) * 2017-09-09 2019-03-14 June Medical Ip, Llc Passive safety intraosseous device
US11484339B2 (en) 2017-09-09 2022-11-01 June Access, IP LLC Passive safety intraosseous device
CN107595327A (en) * 2017-10-20 2018-01-19 中国人民解放军第四军医大学 Parathyroid gland accurately identifies method and its detection means in art
CN108309364A (en) * 2018-02-06 2018-07-24 重庆医科大学附属永川医院 A kind of marrow puncture device and its piercing method
US11191550B2 (en) 2018-02-20 2021-12-07 Piper Access, Llc Medical drilling devices and related systems and methods
WO2019173411A1 (en) * 2018-03-05 2019-09-12 Piper Access, Llc Bone biopsy devices, systems, and methods
CN111954484A (en) * 2018-04-11 2020-11-17 波士顿科学国际有限公司 Apparatus and method for extending a working channel
CN108836444A (en) * 2018-05-08 2018-11-20 徐州蓝湖信息科技有限公司 A kind of clinical medicine stem cell extraction puncturing structure
US11534145B2 (en) 2018-10-12 2022-12-27 Aperture Medical Technology Llc Bone marrow access apparatus and methods for locating same
US11871950B2 (en) 2019-02-25 2024-01-16 Covidien Lp Tissue resecting device including a motor cooling assembly
US10898218B2 (en) 2019-02-25 2021-01-26 Covidien Lp Tissue resecting device including a motor cooling assembly
US11540843B2 (en) 2019-06-28 2023-01-03 H&M Innovations, Llc Harvesting cancellous bone and marrow from distal femur, proximal tibia, distal tibia, or calcaneus using bone press apparatus
US11344319B2 (en) 2019-06-28 2022-05-31 H & M Innovations, Llc Harvesting cancellous bone and marrow from intramedullary canal formed in medullary cavity using bone press apparatus
WO2020264463A1 (en) * 2019-06-28 2020-12-30 H & M Innovations, Llc Harvesting cancellous bone and bone marrow using bone press apparatus
WO2021062394A1 (en) * 2019-09-27 2021-04-01 Bard Access Systems, Inc. Various operating mechanisms for intraosseous access medical devices and methods thereof
US11759235B2 (en) 2019-09-27 2023-09-19 Bard Access Systems, Inc. Constant-torque intraosseous access devices and methods thereof
US11633214B2 (en) 2019-09-27 2023-04-25 Bard Access Systems, Inc. Various operating mechanisms for intraosseous access medical devices and methods thereof
US11517349B2 (en) 2019-09-27 2022-12-06 Bard Access Systems, Inc. Autovance feature of an intraosseous device
US20210259803A1 (en) * 2020-02-25 2021-08-26 Amit R. Patel Drill for surgical screw insertion with reoriented torque
US11911233B2 (en) * 2020-02-25 2024-02-27 Amit R. Patel Drill for surgical screw insertion with reoriented torque
US11896264B2 (en) 2020-04-21 2024-02-13 Bard Access Systems, Inc. Reusable push-activated intraosseous access device
CN112245671A (en) * 2020-11-02 2021-01-22 王天琦 Gall bladder puncture drainage check out test set
CN113317849A (en) * 2021-04-22 2021-08-31 卫飞 Bone puncture needle emitter
CN113575570A (en) * 2021-09-01 2021-11-02 河南中博科技有限公司 Method for manufacturing plasticized specimen not easy to mildew
US11925361B2 (en) 2022-02-08 2024-03-12 Bard Access Systems, Inc. Intraosseous modular power

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