JP2006513238A5 - - Google Patents
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- Publication number
- JP2006513238A5 JP2006513238A5 JP2004565235A JP2004565235A JP2006513238A5 JP 2006513238 A5 JP2006513238 A5 JP 2006513238A5 JP 2004565235 A JP2004565235 A JP 2004565235A JP 2004565235 A JP2004565235 A JP 2004565235A JP 2006513238 A5 JP2006513238 A5 JP 2006513238A5
- Authority
- JP
- Japan
- Prior art keywords
- iminoethyl
- cysteine
- ethyl
- amino
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- NWBJAUFHPXRBKI-QMMMGPOBSA-N (2R)-2-amino-3-[2-(1-aminoethylideneamino)ethylsulfanyl]-2-methylpropanoic acid Chemical compound CC(=N)NCCSC[C@](C)(N)C(O)=O NWBJAUFHPXRBKI-QMMMGPOBSA-N 0.000 claims 1
- -1 1- Iminoethyl Chemical group 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 150000003840 hydrochlorides Chemical class 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
Claims (1)
- Ｓ−［２−［（１−イミノエチル）アミノ］エチル］−２−メチル−Ｌ−システインまたはその塩酸塩および少なくとも１種の非‐吸湿性ポリマーを含む固体粒子状組成物であって、前記Ｓ−［２−［（１−イミノエチル）アミノ］エチル］−２−メチル−Ｌ−システインまたはその塩酸塩および前記少なくとも１種の非‐吸湿性ポリマーが、まず水性液体中に共-分散されて次いで前記液体が除去され、ここで前記組成物が、２１〜２３℃の温度で４０％の相対湿度の条件に２４時間曝した場合、約１０％以下の質量増加を前記組成物が示すように非‐吸湿性である、前記固体粒子状組成物。
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43502202P | 2002-12-19 | 2002-12-19 | |
| US43514702P | 2002-12-19 | 2002-12-19 | |
| US43542202P | 2002-12-19 | 2002-12-19 | |
| PCT/US2003/038792 WO2004060352A1 (en) | 2002-12-19 | 2003-12-05 | Non-hygroscopic formulation comprising a hydroscopic drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006513238A JP2006513238A (ja) | 2006-04-20 |
| JP2006513238A5 true JP2006513238A5 (ja) | 2006-08-10 |
Family
ID=32719157
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004565235A Pending JP2006513238A (ja) | 2002-12-19 | 2003-12-05 | 吸湿性薬物を含む非‐吸湿性製剤 |
| JP2004565403A Withdrawn JP2006514052A (ja) | 2002-12-19 | 2003-12-11 | 吸湿性および／または潮解性の薬剤を含む固体分散剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004565403A Withdrawn JP2006514052A (ja) | 2002-12-19 | 2003-12-11 | 吸湿性および／または潮解性の薬剤を含む固体分散剤 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20050013856A1 (ja) |
| EP (2) | EP1575563B1 (ja) |
| JP (2) | JP2006513238A (ja) |
| AR (2) | AR042511A1 (ja) |
| AT (1) | ATE353633T1 (ja) |
| AU (2) | AU2003298010A1 (ja) |
| BR (2) | BR0317392A (ja) |
| CA (2) | CA2511385A1 (ja) |
| DE (1) | DE60311875T2 (ja) |
| ES (1) | ES2280835T3 (ja) |
| HN (1) | HN2003000417A (ja) |
| MX (2) | MXPA05006802A (ja) |
| NL (1) | NL1025069C2 (ja) |
| PE (1) | PE20040972A1 (ja) |
| TW (2) | TW200423971A (ja) |
| UY (1) | UY28138A1 (ja) |
| WO (2) | WO2004060352A1 (ja) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2262567T3 (es) | 2001-03-20 | 2006-12-01 | Schwarz Pharma Ag | Nuevo uso de una clase peptidica de compuesto para tratamiento del dolor inflamatorio no neuropatico. |
| DK1243263T3 (da) * | 2001-03-21 | 2003-03-17 | Sanol Arznei Schwarz Gmbh | Hidtil ukendt anvendelse af en klasse af peptidforbindelser til behandling af allodyni eller andre forskellige typer af kronisk- eller fantomsmerte |
| SE521512C2 (sv) * | 2001-06-25 | 2003-11-11 | Niconovum Ab | Anordning för administrering av en substans till främre delen av en individs munhåla |
| CA2511385A1 (en) * | 2002-12-19 | 2004-07-22 | Pharmacia Corporation | Non-hygroscopic formulation comprising a hydroscopic drug |
| JP4708795B2 (ja) * | 2002-12-20 | 2011-06-22 | ニコノヴァム エービー | 物理的および化学的に安定なニコチン−含有粒状物質 |
| US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| FR2865133B1 (fr) * | 2004-01-19 | 2008-01-18 | Rytek | Compositions pour le traitement de pathologies digestives |
| EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
| US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
| EA013591B1 (ru) | 2004-04-16 | 2010-06-30 | Шварц Фарма Аг | Применение пептидных соединений для профилактики, облегчения и лечения головной боли и болезненных состояний, связанных с или вызванных распространяющейся кортикальной депрессией (csd) |
| ATE438390T1 (de) * | 2004-07-02 | 2009-08-15 | Radi Medical Biodegradable Ab | Rauchloses tabakprodukt |
| EP1781276B1 (en) | 2004-08-27 | 2010-06-23 | UCB Pharma GmbH | Use of peptide compounds for treating bone cancer pain, chemotherapy- and nucleoside-induced pain |
| US20060147518A1 (en) * | 2004-12-30 | 2006-07-06 | Pierre Fabre Medicament | Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
| US20070048372A1 (en) * | 2005-08-18 | 2007-03-01 | Srz Properties, Inc. | Method for treating non-inflammatory osteoarthritic pain |
| US20090304786A1 (en) * | 2005-11-25 | 2009-12-10 | Viswaprasad Varanasi | Stable Dosage Forms of an Antidepressant |
| CA2646942C (en) | 2006-03-16 | 2014-07-29 | Niconovum Ab | Improved snuff composition |
| DK2029110T3 (da) * | 2006-06-06 | 2011-12-19 | Tibotec Pharm Ltd | Fremgangsmåde til fremstilling af sprøjtetørrede formuleringer med TMC125 |
| AR061476A1 (es) * | 2006-06-15 | 2008-08-27 | Sanol Arznei Schwarz Gmbh | Composicion farmaceutica con efecto anticonvulsivo sinergico |
| EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
| JP5484910B2 (ja) * | 2006-12-22 | 2014-05-07 | ユーハン・コーポレイション | レバプラザン含有の固体分散体及びその製造方法 |
| EP2185472A1 (en) * | 2007-08-30 | 2010-05-19 | Prelief Inc. | Calcium glycerophosphate for treating and preventing respiratory diseases or conditions |
| US9358242B2 (en) | 2007-08-30 | 2016-06-07 | Prelief Inc. | Calcium glycerophosphate for treating and preventing respiratory diseases or conditions |
| KR101499533B1 (ko) * | 2008-02-15 | 2015-03-09 | 주식회사 씨티씨바이오 | 콜린 알포세레이트 함유 약학 제제 |
| DE102008020701A1 (de) * | 2008-04-24 | 2009-10-29 | Bayer Technology Services Gmbh | Formulierung mit reduzierter Hygroskopizität |
| DE102008047910A1 (de) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tablettierhilfsstoff auf Laktose- und Cellulosebasis |
| KR101172699B1 (ko) | 2011-05-16 | 2012-08-09 | 한국프라임제약주식회사 | 콜린알포세레이트를 함유하는 약학 제제, 및 그의 제조방법 |
| JP2014522893A (ja) | 2011-07-07 | 2014-09-08 | ザ ルブリゾル コーポレイション | ２ストロークサイクルエンジンのための改善された清浄性を提供する潤滑剤 |
| CN102525992A (zh) * | 2012-03-09 | 2012-07-04 | 徐奎 | L-α-甘油磷酸胆碱薄膜衣片及其制备方法 |
| ES2924478T3 (es) | 2012-03-15 | 2022-10-07 | Boehringer Ingelheim Vetmedica Gmbh | Formulación de comprimidos farmacéuticos para el sector médico veterinario, método de producción y uso de los mismos |
| US20150141457A1 (en) * | 2012-05-21 | 2015-05-21 | Hetero Research Foundation | Elvitegravir solid dispersion |
| CN105377235A (zh) | 2013-07-19 | 2016-03-02 | 勃林格殷格翰动物保健有限公司 | 含有防腐的醚化的环糊精衍生物的液体水性药物组合物 |
| BR112016011111B1 (pt) * | 2013-12-04 | 2022-11-16 | Boehringer Ingelheim Vetmedica Gmbh | Composições farmacêuticas aprimoradas de pimobendan |
| GB2525170A (en) * | 2014-04-07 | 2015-10-21 | Nokia Technologies Oy | Stereo viewing |
| CN104739776A (zh) * | 2015-04-15 | 2015-07-01 | 福州乾正药业有限公司 | 左卡尼汀的固体分散体组合物及其制备方法和药物应用 |
| WO2017013591A1 (en) * | 2015-07-22 | 2017-01-26 | Leiutis Pharmaceuticals Pvt Ltd | Stabilized liquid formulation of levothyroxine |
| MX2018011348A (es) * | 2016-03-18 | 2019-07-12 | Brian Reid Christopher | Composiciones de extractos naturales y uso de los mismos para prevenir o tratar enfermedades. |
| US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
| JP7319247B2 (ja) * | 2018-03-30 | 2023-08-01 | 株式会社カネカ | 酸化型グルタチオンを含む固体組成物及びその製造方法 |
| CN112316678A (zh) * | 2020-10-12 | 2021-02-05 | 常州市永勃机械有限公司 | 一种变电站柜体用驱潮剂制备工艺制备方法 |
| IT202100018578A1 (it) * | 2021-07-14 | 2023-01-14 | Indena Spa | Dispersione amorfa di maltolo ferrico e relativo processo di preparazione |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4835187A (en) * | 1987-06-15 | 1989-05-30 | American Home Products Corporation | Spray dried ibuprofen |
| JPH02218621A (ja) * | 1989-02-20 | 1990-08-31 | Nippon Chemiphar Co Ltd | 徐放性製剤 |
| US5582837A (en) * | 1992-03-25 | 1996-12-10 | Depomed, Inc. | Alkyl-substituted cellulose-based sustained-release oral drug dosage forms |
| SE9303574D0 (sv) * | 1993-11-01 | 1993-11-01 | Kabi Pharmacia Ab | Composition for drug delivery and method the manufacturing thereof |
| US5688510A (en) * | 1993-11-18 | 1997-11-18 | Nippon Shinyaku Co. Ltd. | Process for producing stable medicinal composition, and pharmaceutical preparation |
| JPH08157392A (ja) * | 1994-12-01 | 1996-06-18 | Kanegafuchi Chem Ind Co Ltd | 放出制御型製剤 |
| GB9607955D0 (en) * | 1996-04-17 | 1996-06-19 | Tillotts Pharma Ag | Hydrophobic carbomer salt compositions |
| JPH10182448A (ja) * | 1996-12-24 | 1998-07-07 | Zensei Yakuhin Kogyo Kk | 圧縮製剤用組成物の製造方法 |
| MA25590A1 (fr) * | 1998-09-14 | 2002-12-31 | Inhale Therapeutic Syst | Agent actif de delivraison de poudre seche |
| US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| ATE295832T1 (de) * | 2000-03-24 | 2005-06-15 | Pharmacia Corp | Amidino-verbindung sowie salze davon verwendbar als hemmstoffe der stickstoffmonoxid-synthase |
| US20020143058A1 (en) * | 2001-01-24 | 2002-10-03 | Taro Pharmaceutical Inductries Ltd. | Process for preparing non-hygroscopic sodium valproate composition |
| CA2511385A1 (en) * | 2002-12-19 | 2004-07-22 | Pharmacia Corporation | Non-hygroscopic formulation comprising a hydroscopic drug |
-
2003
- 2003-12-05 CA CA002511385A patent/CA2511385A1/en not_active Abandoned
- 2003-12-05 EP EP03796731A patent/EP1575563B1/en not_active Expired - Lifetime
- 2003-12-05 ES ES03796731T patent/ES2280835T3/es not_active Expired - Lifetime
- 2003-12-05 DE DE60311875T patent/DE60311875T2/de not_active Expired - Fee Related
- 2003-12-05 WO PCT/US2003/038792 patent/WO2004060352A1/en active IP Right Grant
- 2003-12-05 AT AT03796731T patent/ATE353633T1/de not_active IP Right Cessation
- 2003-12-05 AU AU2003298010A patent/AU2003298010A1/en not_active Abandoned
- 2003-12-05 BR BR0317392-5A patent/BR0317392A/pt not_active IP Right Cessation
- 2003-12-05 MX MXPA05006802A patent/MXPA05006802A/es unknown
- 2003-12-05 JP JP2004565235A patent/JP2006513238A/ja active Pending
- 2003-12-11 CA CA002509261A patent/CA2509261A1/en not_active Abandoned
- 2003-12-11 MX MXPA05005667A patent/MXPA05005667A/es unknown
- 2003-12-11 BR BR0317103-5A patent/BR0317103A/pt not_active IP Right Cessation
- 2003-12-11 WO PCT/US2003/039510 patent/WO2004060353A1/en not_active Application Discontinuation
- 2003-12-11 AU AU2003296948A patent/AU2003296948A1/en not_active Abandoned
- 2003-12-11 EP EP03814729A patent/EP1575564A1/en not_active Withdrawn
- 2003-12-11 JP JP2004565403A patent/JP2006514052A/ja not_active Withdrawn
- 2003-12-17 AR ARP030104684A patent/AR042511A1/es unknown
- 2003-12-17 TW TW092135756A patent/TW200423971A/zh unknown
- 2003-12-18 TW TW092135960A patent/TW200413006A/zh unknown
- 2003-12-18 US US10/741,526 patent/US20050013856A1/en not_active Abandoned
- 2003-12-18 US US10/741,530 patent/US20040197411A1/en not_active Abandoned
- 2003-12-18 NL NL1025069A patent/NL1025069C2/nl not_active IP Right Cessation
- 2003-12-18 AR ARP030104716A patent/AR042536A1/es unknown
- 2003-12-19 HN HN2003000417A patent/HN2003000417A/es unknown
- 2003-12-19 UY UY28138A patent/UY28138A1/es not_active Application Discontinuation
-
2004
- 2004-01-05 PE PE2004000027A patent/PE20040972A1/es not_active Application Discontinuation
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