JP2005520821A5 - - Google Patents
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- Publication number
- JP2005520821A5 JP2005520821A5 JP2003575716A JP2003575716A JP2005520821A5 JP 2005520821 A5 JP2005520821 A5 JP 2005520821A5 JP 2003575716 A JP2003575716 A JP 2003575716A JP 2003575716 A JP2003575716 A JP 2003575716A JP 2005520821 A5 JP2005520821 A5 JP 2005520821A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- formula
- compound
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *c1c(*=C)c(N(*)*)nc(*)n1 Chemical compound *c1c(*=C)c(N(*)*)nc(*)n1 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02405201 | 2002-03-15 | ||
| PCT/EP2003/002438 WO2003077656A1 (en) | 2002-03-15 | 2003-03-10 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005520821A JP2005520821A (ja) | 2005-07-14 |
| JP2005520821A5 true JP2005520821A5 (https=) | 2006-04-20 |
Family
ID=27838195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003575716A Pending JP2005520821A (ja) | 2002-03-15 | 2003-03-10 | 4−アミノピリミジン及び表面の抗菌処理のためのその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7731985B2 (https=) |
| EP (1) | EP1484971B1 (https=) |
| JP (1) | JP2005520821A (https=) |
| CN (1) | CN1642422A (https=) |
| AT (1) | ATE366045T1 (https=) |
| AU (1) | AU2003214110A1 (https=) |
| DE (1) | DE60314730T2 (https=) |
| ES (1) | ES2290436T3 (https=) |
| WO (1) | WO2003077656A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037916B2 (en) * | 1999-07-15 | 2006-05-02 | Pharmacopeia Drug Discovery, Inc. | Pyrimidine derivatives as IL-8 receptor antagonists |
| MXPA05007485A (es) * | 2003-01-14 | 2006-01-30 | Arena Pharm Inc | Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia. |
| SI1599468T1 (sl) | 2003-01-14 | 2008-02-29 | Arena Pharm Inc | 1,2,3-trisubstituirani arilni in heteroarilni derivati kot modulatorji metabolizma ter profilaksa in zdravljenje motenj v zvezi z njim, kot diabetesain hiperglikemije |
| AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| JP2007506746A (ja) | 2003-09-24 | 2007-03-22 | ワイス・ホールディングズ・コーポレイション | 抗癌剤としての5−アリールピリミジン類 |
| GB0323137D0 (en) | 2003-10-03 | 2003-11-05 | Chang Lisa C W | 2,4,6- Trisubstituted pyrimidines and their different uses |
| WO2005099711A1 (en) * | 2004-04-13 | 2005-10-27 | Icagen, Inc. | Polycyclic pyrimidines as potassium ion channel modulators |
| PH12013500547A1 (en) | 2010-09-22 | 2013-06-10 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| JP6116554B2 (ja) * | 2011-07-07 | 2017-04-19 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | がんの処置のための置換されたアザ複素環 |
| AR090880A1 (es) | 2012-04-30 | 2014-12-10 | Janssen R & D Ireland | Derivados de pirimidina |
| CA2896731A1 (en) | 2012-12-28 | 2014-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibitors of the usp1/uaf1 deubiquitinase complex and uses thereof |
| MX386419B (es) | 2015-01-06 | 2025-03-18 | Arena Pharm Inc | Metodos de condiciones de tratamiento relacionadas con el receptor s1p1. |
| EP3939965A1 (en) | 2015-06-22 | 2022-01-19 | Arena Pharmaceuticals, Inc. | Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in sipi receptor-associated disorders |
| MA47504A (fr) | 2017-02-16 | 2019-12-25 | Arena Pharm Inc | Composés et méthodes de traitement de l'angiocholite biliaire primitive |
| CA3058813A1 (en) * | 2017-04-05 | 2018-10-11 | University Of Utah Research Foundation | Compositions and methods comprising a triaryl polyamine |
| CN108162528B (zh) * | 2017-12-22 | 2020-07-10 | 宿迁市金田塑业有限公司 | 一种新型高性能抗菌防雾膜 |
| ES2987794T3 (es) | 2018-06-06 | 2024-11-18 | Arena Pharm Inc | Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1 |
| US11993580B1 (en) | 2022-12-02 | 2024-05-28 | Neumora Therapeutics, Inc. | Methods of treating neurological disorders |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1143167A (en) * | 1967-01-25 | 1969-02-19 | Ucb Sa | Derivatives of pyrimidine |
| US3755583A (en) * | 1970-06-05 | 1973-08-28 | Chas0!nhx | |
| US3707560A (en) * | 1970-10-05 | 1972-12-26 | Pfizer | Certain 4-amino-6-aryl-pyrimidines |
| DE2202385A1 (de) * | 1972-01-19 | 1973-07-26 | Boehringer Mannheim Gmbh | Nitrofuran-derivate |
| US4144338A (en) * | 1977-02-17 | 1979-03-13 | Merck & Co., Inc. | N-pyrimidinyl-N-dialkylaminoalkyl ureas |
| JPS6059883B2 (ja) * | 1978-05-08 | 1985-12-27 | 北興化学工業株式会社 | 農園芸用殺菌剤 |
| MA18829A1 (fr) * | 1979-05-18 | 1980-12-31 | Ciba Geigy Ag | Derives de la pyrimidine,procedes pour leur preparation,compositions pharmaceutiques contenant ces composes et leur utilisation therapeutique |
| JPS57126481A (en) * | 1981-01-29 | 1982-08-06 | Sankyo Co Ltd | Aminopyrimidine derivative, fungicide, insecticide, and acaricide |
| PH20344A (en) * | 1981-01-29 | 1986-12-04 | Sankyo Co | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them |
| JPS57176967A (en) * | 1981-04-21 | 1982-10-30 | Sankyo Co Ltd | Aminopyrimidine derivative and antibacterial, insecticidal and miticidal agent |
| JPS5936666A (ja) * | 1982-07-23 | 1984-02-28 | Sankyo Co Ltd | アミノピリミジン誘導体 |
| EP0136976A3 (de) * | 1983-08-23 | 1985-05-15 | Ciba-Geigy Ag | Verwendung von Phenylpyrimidinen als Pflanzenregulatoren |
| GB8417852D0 (en) * | 1984-07-13 | 1984-08-15 | Fujisawa Pharmaceutical Co | Pyrimidine derivatives |
| DE3642452A1 (de) * | 1986-12-12 | 1988-06-23 | Bayer Ag | Substituierte 4-amino-pyrimidine |
| JPH01250363A (ja) * | 1987-12-28 | 1989-10-05 | Kumiai Chem Ind Co Ltd | 4―ベンジルアミノピリミジン誘導体及び除草剤 |
| JPH0745481B2 (ja) * | 1988-01-07 | 1995-05-17 | 宇部興産株式会社 | アルキルアミノピリミジン誘導体、その製造法ならびに該誘導体を有効成分とする殺虫剤、殺ダニ剤および殺菌剤 |
| US4931455A (en) * | 1988-01-07 | 1990-06-05 | Ube Industries, Ltd. | Alkylaminopyrimidine derivative and insecticide, acaricide and fungicide containing the same as active ingredient |
| DE3922735A1 (de) * | 1989-07-11 | 1991-01-24 | Hoechst Ag | Aminopyrimidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide |
| JPH0368563A (ja) * | 1989-08-09 | 1991-03-25 | Kumiai Chem Ind Co Ltd | (S)―α―メチルベンジルアミノピリミジン誘導体及び除草剤 |
| EP0424125A3 (en) * | 1989-10-18 | 1991-10-09 | Ube Industries, Ltd. | Aralkylamine derivatives, preparation method thereof and fungicides containing the same |
| US5589477A (en) * | 1990-08-31 | 1996-12-31 | Nippon Shinyaku Company, Limited | Pyrimidine derivatives and drugs |
| DE4031798A1 (de) * | 1990-10-08 | 1992-04-09 | Hoechst Ag | Pyridylpyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide |
| DE4034762A1 (de) * | 1990-11-02 | 1992-05-07 | Hoechst Ag | Pyridylpyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide |
| ATE176226T1 (de) * | 1990-11-19 | 1999-02-15 | Du Pont | Insektizide, akarizide und fungizide aminopyrimidine |
| EP0519211A1 (de) * | 1991-05-17 | 1992-12-23 | Hoechst Schering AgrEvo GmbH | Substituierte 4-Aminopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
| JPH05194418A (ja) * | 1992-01-23 | 1993-08-03 | Kirin Brewery Co Ltd | 2−アミノピリミジン誘導体及びその用途 |
| JP3086316B2 (ja) * | 1992-01-31 | 2000-09-11 | アグロカネショウ株式会社 | フェニルカーバメート誘導体、その製造法及び該誘導体を有効成分とする農園芸用殺菌剤 |
| JP2649119B2 (ja) * | 1992-04-21 | 1997-09-03 | 宇部興産株式会社 | アルキルアミノピリミジン化合物、その製法及び有害生物防除剤 |
| US5354738A (en) * | 1992-09-04 | 1994-10-11 | G. D. Searle & Co. | Platelet aggregation inhibitors |
| AU7551894A (en) | 1993-09-09 | 1995-03-27 | E.I. Du Pont De Nemours And Company | Fungicidal, miticidal and arthropodicidal aminopyrimidines |
| AU7938994A (en) * | 1993-10-25 | 1995-05-22 | Shell Internationale Research Maatschappij B.V. | Pyrimidine derivatives |
| JPH08283246A (ja) * | 1994-06-01 | 1996-10-29 | Nippon Soda Co Ltd | ピリミジン誘導体、その製造方法及び有害生物防除剤 |
| DE19511562A1 (de) * | 1995-03-29 | 1996-10-02 | Hoechst Schering Agrevo Gmbh | Cyclohexylamino- und alkoxy-Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide |
| DE19600934A1 (de) * | 1996-01-12 | 1997-07-17 | Basf Ag | Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung |
| US6011029A (en) * | 1996-02-26 | 2000-01-04 | Bristol-Myers Squibb Company | Inhibitors of farnesyl protein transferase |
| DE19613329A1 (de) * | 1996-04-03 | 1997-10-09 | Hoechst Schering Agrevo Gmbh | Substituierte Pyridine/Pyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
| JPH10130149A (ja) * | 1996-07-12 | 1998-05-19 | Sankyo Co Ltd | Tnf産生抑制剤 |
| JPH11246528A (ja) * | 1997-12-05 | 1999-09-14 | Tomono Agrica Co Ltd | 含窒素芳香族化合物およびその塩 |
| PT1091957E (pt) | 1998-05-23 | 2005-05-31 | Altana Pharma Ag | Derivados de pirimidino-aminometil-piridina, sua preparacao e sua utilizacao no comtrolo de bacterias helicobacter |
| GB9816729D0 (en) * | 1998-08-01 | 1998-09-30 | Hoechst Schering Agrevo Gmbh | Substituted cyclohexylaminopyrimidines |
| DE19836697A1 (de) | 1998-08-13 | 2000-02-17 | Hoechst Marion Roussel De Gmbh | Substituierte 4-Amino-2-aryl-pyrimidine, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| JP2001139561A (ja) * | 1999-11-17 | 2001-05-22 | Dainippon Pharmaceut Co Ltd | 5−ハロゲノ−6−(4−トリフルオロメチルフェニル)−4−アミノピリミジン誘導体 |
| JP2001247411A (ja) * | 2000-03-09 | 2001-09-11 | Tomono Agrica Co Ltd | 有害生物防除剤 |
| GB0018951D0 (en) * | 2000-08-03 | 2000-09-20 | Smithkline Beecham Plc | Novel compounds |
| CN1473156A (zh) * | 2000-11-10 | 2004-02-04 | - | 嘧啶衍生物及其作为神经肽y受体配体的用途 |
| US20020137755A1 (en) * | 2000-12-04 | 2002-09-26 | Bilodeau Mark T. | Tyrosine kinase inhibitors |
| PL364625A1 (en) * | 2001-02-23 | 2004-12-13 | Merck & Co, Inc. | N-substituted nonaryl-heterocyclic nmda/nr2b antagonists |
| DE60204509T2 (de) * | 2001-04-20 | 2006-03-16 | Ciba Speciality Chemicals Holding Inc. | 4-Amino-2-(2-pyridinyl)pyrimidine als mikrobizide Wirksubstanzen |
| EP1254903B1 (en) * | 2001-04-20 | 2005-06-08 | Ciba SC Holding AG | 4-Amino-2-(pyridin-2-yl)pyrimidine as microbicidal active substances |
| DE10131543A1 (de) * | 2001-06-29 | 2003-01-16 | Abbott Lab | Pyrimidinoxyalkylpiperazine und ihre therapeutische Verwendung |
| WO2003026661A1 (fr) * | 2001-09-14 | 2003-04-03 | Yamanouchi Pharmaceutical Co., Ltd. | Accelerateur de secretion de l'insuline et nouveau derive de pyrimidine |
| GB0226724D0 (en) * | 2002-11-15 | 2002-12-24 | Merck Sharp & Dohme | Therapeutic agents |
| US7423148B2 (en) * | 2002-11-21 | 2008-09-09 | Chiron Corporation | Small molecule PI 3-kinase inhibitors and methods of their use |
-
2003
- 2003-03-10 AU AU2003214110A patent/AU2003214110A1/en not_active Abandoned
- 2003-03-10 CN CNA038059894A patent/CN1642422A/zh active Pending
- 2003-03-10 US US10/507,800 patent/US7731985B2/en not_active Expired - Fee Related
- 2003-03-10 WO PCT/EP2003/002438 patent/WO2003077656A1/en not_active Ceased
- 2003-03-10 EP EP03709767A patent/EP1484971B1/en not_active Expired - Lifetime
- 2003-03-10 JP JP2003575716A patent/JP2005520821A/ja active Pending
- 2003-03-10 DE DE60314730T patent/DE60314730T2/de not_active Expired - Lifetime
- 2003-03-10 ES ES03709767T patent/ES2290436T3/es not_active Expired - Lifetime
- 2003-03-10 AT AT03709767T patent/ATE366045T1/de not_active IP Right Cessation
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