JP2003503454A5 - - Google Patents

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Publication number
JP2003503454A5
JP2003503454A5 JP2001507476A JP2001507476A JP2003503454A5 JP 2003503454 A5 JP2003503454 A5 JP 2003503454A5 JP 2001507476 A JP2001507476 A JP 2001507476A JP 2001507476 A JP2001507476 A JP 2001507476A JP 2003503454 A5 JP2003503454 A5 JP 2003503454A5
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JP
Japan
Prior art keywords
parkinson
medicament
disease
manufacture
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001507476A
Other languages
English (en)
Japanese (ja)
Other versions
JP4204783B2 (ja
JP2003503454A (ja
Filing date
Publication date
Priority claimed from FI991485A external-priority patent/FI109453B/fi
Application filed filed Critical
Publication of JP2003503454A publication Critical patent/JP2003503454A/ja
Publication of JP2003503454A5 publication Critical patent/JP2003503454A5/ja
Application granted granted Critical
Publication of JP4204783B2 publication Critical patent/JP4204783B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2001507476A 1999-06-30 2000-06-29 レボドパ/カルビドパ/エンタカポン医薬製剤 Expired - Lifetime JP4204783B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI991485A FI109453B (fi) 1999-06-30 1999-06-30 Farmaseuttinen koostumus
FI991485 1999-06-30
PCT/FI2000/000593 WO2001001984A1 (en) 1999-06-30 2000-06-29 Levodopa / carbidopa / entacapone pharmaceutical preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008063280A Division JP4885896B2 (ja) 1999-06-30 2008-03-12 レボドパ/カルビドパ/エンタカポン医薬製剤

Publications (3)

Publication Number Publication Date
JP2003503454A JP2003503454A (ja) 2003-01-28
JP2003503454A5 true JP2003503454A5 (enExample) 2007-06-07
JP4204783B2 JP4204783B2 (ja) 2009-01-07

Family

ID=8554988

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001507476A Expired - Lifetime JP4204783B2 (ja) 1999-06-30 2000-06-29 レボドパ/カルビドパ/エンタカポン医薬製剤
JP2008063280A Expired - Lifetime JP4885896B2 (ja) 1999-06-30 2008-03-12 レボドパ/カルビドパ/エンタカポン医薬製剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008063280A Expired - Lifetime JP4885896B2 (ja) 1999-06-30 2008-03-12 レボドパ/カルビドパ/エンタカポン医薬製剤

Country Status (42)

Country Link
US (2) US6500867B1 (enExample)
EP (1) EP1189608B1 (enExample)
JP (2) JP4204783B2 (enExample)
KR (1) KR100905428B1 (enExample)
CN (1) CN1168440C (enExample)
AR (1) AR033796A1 (enExample)
AT (1) ATE245417T1 (enExample)
AU (1) AU765932B2 (enExample)
BG (1) BG65364B1 (enExample)
BR (2) BRPI0011867B8 (enExample)
CA (1) CA2378469C (enExample)
CO (1) CO5180579A1 (enExample)
CZ (2) CZ304416B6 (enExample)
DE (1) DE60004052T2 (enExample)
DK (1) DK1189608T3 (enExample)
EA (1) EA004503B1 (enExample)
EE (1) EE05473B1 (enExample)
ES (1) ES2203495T3 (enExample)
FI (1) FI109453B (enExample)
FR (1) FR2797587A1 (enExample)
GE (1) GEP20043314B (enExample)
HK (1) HK1047040B (enExample)
HR (1) HRP20020088B1 (enExample)
HU (1) HU230395B1 (enExample)
IL (1) IL146807A (enExample)
IT (1) ITMI20001450A1 (enExample)
ME (1) ME00520B (enExample)
MX (1) MXPA01013167A (enExample)
MY (1) MY127685A (enExample)
NO (2) NO330260B1 (enExample)
NZ (1) NZ515780A (enExample)
PE (1) PE20010399A1 (enExample)
PL (1) PL197818B1 (enExample)
PT (1) PT1189608E (enExample)
RS (1) RS50368B (enExample)
SI (1) SI1189608T1 (enExample)
SK (1) SK286451B6 (enExample)
TR (1) TR200103763T2 (enExample)
TW (1) TWI241187B (enExample)
UA (1) UA75047C2 (enExample)
WO (1) WO2001001984A1 (enExample)
ZA (1) ZA200109868B (enExample)

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US20040006072A1 (en) * 2002-06-25 2004-01-08 Franz Robert M. Sustained-release alprazolam composition
US20040180086A1 (en) * 2002-10-11 2004-09-16 Zebunnissa Ramtoola Gastro-retentive levodopa delivery form
AR044007A1 (es) 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
SE0401842D0 (sv) 2004-07-12 2004-07-12 Dizlin Medical Design Ab Infusion and injection solution of levodopa
WO2006037061A2 (en) * 2004-09-28 2006-04-06 Farouk Karoum Compositions and methods of using d-dopa to treat parkinson's disease
US20060173074A1 (en) 2004-11-10 2006-08-03 Juha Ellmen Treatment of restless legs syndrome
AU2012216377C1 (en) * 2005-06-08 2013-10-10 Orion Corporation Oral dosage form
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US20070003621A1 (en) * 2005-06-23 2007-01-04 Spherics, Inc. Dosage forms for movement disorder treatment
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
US8168793B2 (en) * 2005-07-26 2012-05-01 Portela & Ca., S.A. Nitrocatechol derivatives as COMT inhibitors
US8877802B2 (en) * 2005-07-28 2014-11-04 Duke Univerity Antiparkinsonian action of phenylisopropylamines
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US20070178149A1 (en) * 2005-11-07 2007-08-02 Moshe Flashner-Barak Levodopa compositions
EP1954256A2 (en) * 2005-11-09 2008-08-13 Torrent Pharmaceuticals Ltd Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
GB2429645A (en) * 2006-03-10 2007-03-07 Sekhsaria Chemicals Ltd Solid pharmaceutical composition comprising a COMT inhibitor, a starch and a wetting agent
CN100384411C (zh) * 2006-03-17 2008-04-30 北京科信必成医药科技发展有限公司 卡左双多巴口腔崩解片
WO2007113371A1 (en) * 2006-03-31 2007-10-11 Iprbox Oy Pharmaceutical composition and preparation method thereof
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
EP1870097A1 (en) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
US20080131492A1 (en) * 2006-06-23 2008-06-05 Spherics, Inc. Dosage forms for movement disorder treatment
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US20100316712A1 (en) * 2006-12-22 2010-12-16 Combinatorx, Incorporated Pharmaceutical compositions for treatment of parkinson's disease and related disorders
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EP1946756A1 (en) * 2007-01-17 2008-07-23 Revotar Biopharmaceuticals AG Use of entacapone in cosmetic, dermatological and pharmaceutical compositions
PL2481410T3 (pl) 2007-01-31 2017-03-31 Bial - Portela & Ca., S.A. Pochodne nitrokatecholu jako inhibitory COMT podawane w określonym schemacie dawkowania
US20110171275A1 (en) * 2007-08-20 2011-07-14 Team Academy Of Pharmaceutical Science Gastroretentive drug delivery system, preparation method and use thereof
MX2010008711A (es) 2008-02-06 2011-05-03 Wockhardt Ltd Composiciones farmaceuticas de entacapona, levopoda y carbidopa, con biodisponibilidad mejorada.
US8728517B2 (en) * 2008-02-06 2014-05-20 Wockhardt Ltd. Pharmaceutical compositions of entacapone co-micronized with sugar alcohols
CL2009000628A1 (es) 2008-03-17 2010-04-09 Bial Portela & Companhia S A Forma cristalina de 5-[3-(2,5-dicloro-4,6-dimetil-1-oxi-piridin-3-il)-[1,2,4]oxadiazol-5-il]-3-nitrobenceno-1,2-diol, composicion farmaceutica que la comprende, proceso para obtenerla y su uso para tratar trastornos del animo, enfermedad de parkinson y trastornos parkinsonianos, alteraciones gastrointestinales, entre otros.
KR20110046555A (ko) 2008-08-22 2011-05-04 욱크하르트 리서치 센터 레보도파, 카비도파 및 엔타카폰 또는 이의 염을 포함하는 단일 단위 경구 투여 약학 조성물
BRPI0916922A2 (pt) * 2008-08-22 2015-11-24 Wockhardt Research Center composição farmacêutica de liberação prolongada de entacapona ou sais da mesma
TR200806646A2 (tr) * 2008-09-03 2009-06-22 Dr. F. Fri̇k İlaç San. Ve Ti̇c. A.Ş. Entakapon, levodopa ve karbidoba içeren farmasötik kombinasyonlar
EP2233131A1 (en) 2009-03-23 2010-09-29 Laboratorios Lesvi, S.L. Pharmaceutical composition containing levodopa, entacapone and carbidopa
US9132094B2 (en) 2009-04-01 2015-09-15 Bial—Portela & Ca, S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making thereof
AU2010250766B2 (en) 2009-05-19 2015-04-09 Neuroderm Ltd Compositions for continuous administration of dopa decarboxylase inhibitors
JP5718937B2 (ja) * 2009-12-25 2015-05-13 イノファーマックス インコーポレイテッド パーキンソン病を治療するための医薬組成物及びその調製方法
CN102781424B (zh) 2010-03-04 2016-03-30 奥赖恩公司 左旋多巴、卡比多巴和恩他卡朋用于治疗帕金森病的应用
DE102010023828A1 (de) * 2010-06-15 2011-12-15 IIP - Institut für industrielle Pharmazie, Forschungs- und Entwicklungsgesellschaft mbH Pharmazeutisches Präparat, welches Entacapon, Levodopa und Carbidopa enthält
NZ610911A (en) * 2010-11-15 2015-02-27 Neuroderm Ltd Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
EP2508174A1 (en) 2011-04-06 2012-10-10 Ljiljana Sovic Brkicic Pharmaceutical composition
WO2012147099A1 (en) * 2011-04-25 2012-11-01 Suven Nishtaa Pharma Pvt. Ltd. Pharmaceutical compositions of levodopa, carbidopa and entacapone
KR101807907B1 (ko) * 2011-04-26 2017-12-11 이노파막스, 인크. 엔타카폰의 조성물
PT2791134T (pt) 2011-12-13 2019-12-18 BIAL PORTELA & Cª S A Composto químico útil como intermediário para a preparação de um inibidor de catecol-o-metiltransferase
TR201204839A2 (tr) 2012-04-25 2012-12-21 Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. Uzatılmış salım sağlayan levodopa karbıdopa entakapon içeren tablet formülasyonu.
US9999674B2 (en) 2012-06-05 2018-06-19 Neuroderm, Ltd. Compositions comprising apomorphine and organic acids and uses thereof
JP6472391B2 (ja) * 2013-03-13 2019-02-20 ニューロダーム リミテッドNeuroderm Ltd パーキンソン病の治療方法
EP2799065A1 (en) * 2013-04-30 2014-11-05 Deva Holding Anonim Sirketi Levodopa carbidopa entacapone pharmaceutical formulations
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
ES2823000T3 (es) 2013-10-07 2021-05-05 Impax Laboratories Llc Formulaciones muco-adhesivas de liberación controlada de levodopa y/o ésteres de levodopa y usos de las mismas
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
MX2016011837A (es) 2014-03-13 2017-04-27 Neuroderm Ltd Composiciones de inhibidores de la dopa decarboxilasa.
JP6622310B2 (ja) 2014-09-04 2019-12-18 ロブソル・ファーマシューティカルズ・アクチボラグLobsor Pharmaceuticals Aktiebolag レボドパ、ドーパミン脱炭酸酵素阻害薬およびcomt阻害薬を含む医薬組成物ならびにその投与方法
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
WO2016101969A1 (en) 2014-12-23 2016-06-30 Pharmathen S.A. Levodopa/carbidopa/entacapone pharmaceutical preparation and method for preparing the same
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ES2895054T3 (es) 2016-08-18 2022-02-17 Ilko Ilac Sanayi Ve Ticaret Anonim Sirketi Fórmula de comprimido antiparkinson con perfil de disolución mejorado
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KR20200136008A (ko) 2018-03-23 2020-12-04 롭서 파마슈티컬스 악티에볼라그 신경퇴행성 장애의 치료를 위한 약제학적 조성물의 연속 투여
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen
JP2024501235A (ja) 2020-12-22 2024-01-11 アムニール ファーマスーティカルズ エルエルシー レボドパ投薬レジメン
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

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US4190672A (en) 1978-09-01 1980-02-26 Stanley Fahn Method and compositions of treating Parkinsonisms with levodopa and 3',4'-dihydroxy-2-methylisopropiophenone
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US5283352A (en) 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
DE4101873C2 (de) 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
US5888534A (en) 1995-06-13 1999-03-30 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
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US6599530B2 (en) 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus

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