|
GB9818731D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
ES2260570T3
(es)
|
1998-08-27 |
2006-11-01 |
Spirogen Limited |
Pirrolobenziodiazepinas dimericas.
|
|
GB9818732D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
CA2520898C
(en)
*
|
2003-03-31 |
2009-10-20 |
Council Of Scientific And Industrial Research |
Non-cross-linking pyrrolo(2,1-c)(1,4)benzodiazepines as potential antitumour agents and process thereof
|
|
GB0321295D0
(en)
*
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
GB0416511D0
(en)
*
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2005040170A2
(en)
|
2003-10-22 |
2005-05-06 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
|
JPWO2005040172A1
(ja)
*
|
2003-10-29 |
2007-03-08 |
協和醗酵工業株式会社 |
三環性プロリン誘導体
|
|
AU2003300720A1
(en)
*
|
2003-12-31 |
2005-07-21 |
Council Of Scientific And Industrial Research |
C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids
|
|
GB2424883B
(en)
*
|
2003-12-31 |
2008-10-22 |
Council Scient Ind Res |
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
|
|
ATE542821T1
(de)
*
|
2004-03-01 |
2012-02-15 |
Spirogen Ltd |
11-hydroxy-5h-pyrroloä2,1-cüä1,4übenzodiazepin- - on derivate als zwischenverbindungen für die herstellung von c2 substituierten pyrrolobenzodiazepinen
|
|
GB0404577D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404578D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404574D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
JP5166861B2
(ja)
|
2004-03-09 |
2013-03-21 |
スピロゲン リミティッド |
ピロロベンゾジアゼピン
|
|
US7056913B2
(en)
|
2004-03-30 |
2006-06-06 |
Council Of Scientific And Industrial Research |
C8—linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
|
|
US6951853B1
(en)
|
2004-03-30 |
2005-10-04 |
Council Of Scientific And Industrial Research |
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
|
|
FR2869231B1
(fr)
*
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
*
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
GB0508084D0
(en)
*
|
2005-04-21 |
2005-06-01 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2006111759A1
(en)
*
|
2005-04-21 |
2006-10-26 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
DE602006006199D1
(de)
*
|
2005-10-05 |
2009-05-20 |
Spirogen Ltd |
4-ä4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo ä2, 1-cüä1,4übenzodiazepin-8-yloxy)-butyrylaminoü-1h-pyrrol-2-carbonsäurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
|
SI1813614T1
(sl)
|
2006-01-25 |
2012-01-31 |
Sanofi 174 |
Citotoksična sredstva, ki obsegajo nove tomajmicinske derivate
|
|
DE102006013678A1
(de)
*
|
2006-03-24 |
2007-09-27 |
Bayerische Motoren Werke Ag |
Gleit- oder Schmiermittel und Verfahren zum Aufziehen eines Fahrzeugreifens auf eine Felge
|
|
AU2007274738B2
(en)
|
2006-07-18 |
2013-11-28 |
Sanofi-Aventis |
Antagonist antibody against EphA2 for the treatment of cancer
|
|
GB0619325D0
(en)
|
2006-09-30 |
2006-11-08 |
Univ Strathclyde |
New compounds
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
ES2435779T3
(es)
|
2007-07-19 |
2013-12-23 |
Sanofi |
Agentes citotóxicos que comprenden nuevos derivados de tomaimicina y su uso terapéutico
|
|
KR20230003298A
(ko)
|
2008-04-30 |
2023-01-05 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
CN105175434A
(zh)
|
2009-02-05 |
2015-12-23 |
伊缪诺金公司 |
新型苯并二氮杂*衍生物
|
|
AU2015224492B2
(en)
*
|
2009-02-05 |
2017-04-20 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
|
SG176068A1
(en)
|
2009-06-03 |
2011-12-29 |
Immunogen Inc |
Conjugation methods
|
|
FR2949469A1
(fr)
*
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
AR078470A1
(es)
|
2009-10-02 |
2011-11-09 |
Sanofi Aventis |
Anticuerpos que se unen especificamente al receptor epha2
|
|
GB201006340D0
(en)
*
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
AU2011239507B2
(en)
|
2010-04-15 |
2015-04-09 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
BR112012026801B8
(pt)
|
2010-04-15 |
2021-05-25 |
Medimmune Ltd |
conjugados de pirrolobenzodiazepina direcionados, composição farmacêutica, uso dos mesmos para tratamento de uma doença proliferativa ou autoimune e ligante de medicamento
|
|
MX368648B
(es)
|
2010-04-15 |
2019-10-09 |
Seattle Genetics Inc |
Pirrolobenzodiazepinas usadas para tratar enfermedades proliferativas.
|
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
|
DK2675480T3
(en)
|
2011-02-15 |
2019-04-15 |
Immunogen Inc |
PROCEDURES FOR PREPARING CONJUGATES
|
|
FR2972006B1
(fr)
|
2011-02-24 |
2016-03-25 |
Centre Nat Rech Scient |
Nouveaux fragments d'il-33 superactifs et leurs utilisations
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
EA027971B1
(ru)
|
2011-09-20 |
2017-09-29 |
Медимьюн Лимитед |
Пирролбензодиазепины
|
|
EP2751111B1
(en)
*
|
2011-10-14 |
2017-04-26 |
MedImmune Limited |
Asymmetrical bis-(5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one) derivatives for the treatment of proliferative or autoimmune diseases
|
|
MX375987B
(es)
*
|
2011-10-14 |
2025-03-07 |
Seagen Inc |
Pirrolobenzodiazepinas y conjugados dirigidos
|
|
US11135303B2
(en)
|
2011-10-14 |
2021-10-05 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
JP6393617B2
(ja)
|
2011-10-14 |
2018-09-19 |
シアトル ジェネティクス，インコーポレーテッド |
ピロロベンゾジアゼピンおよび標的コンジュゲート
|
|
WO2013053872A1
(en)
|
2011-10-14 |
2013-04-18 |
Spirogen Sàrl |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
|
CA2850264C
(en)
|
2011-10-14 |
2019-11-05 |
Spirogen Sarl |
Pyrrolobenzodiazepines
|
|
WO2013126810A1
(en)
|
2012-02-24 |
2013-08-29 |
Stem Centrx, Inc. |
Anti sez6 antibodies and methods of use
|
|
BR112014020826A8
(pt)
|
2012-02-24 |
2017-09-19 |
Stem Centrx Inc |
Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
IN2014MN02092A
(cg-RX-API-DMAC7.html)
|
2012-04-30 |
2015-09-04 |
Spirogen Sarl |
|
|
NZ701478A
(en)
|
2012-04-30 |
2016-08-26 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
EP2844300B1
(en)
|
2012-05-01 |
2018-10-17 |
Genentech, Inc. |
Anti-pmel17 antibodies and immunoconjugates
|
|
CN104540526A
(zh)
|
2012-07-09 |
2015-04-22 |
基因泰克公司 |
包含抗cd79b抗体的免疫偶联物
|
|
AU2013288929A1
(en)
|
2012-07-09 |
2014-12-04 |
Genentech, Inc. |
Immunoconjugates comprising anti-CD22 antibodies
|
|
US9464141B2
(en)
|
2012-08-02 |
2016-10-11 |
Genentech, Inc. |
Anti-ETBR antibodies and immunoconjugates
|
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
HRP20180945T1
(hr)
|
2012-10-12 |
2018-08-10 |
Adc Therapeutics Sa |
Konjugati protutijelo-pirolobenzodiazepin
|
|
JP6270859B2
(ja)
|
2012-10-12 |
2018-01-31 |
エイディーシー・セラピューティクス・エス・アー・エール・エルＡｄｃ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｓａｒｌ |
ピロロベンゾジアゼピン−抗体結合体
|
|
EP3470086B1
(en)
|
2012-10-12 |
2020-11-25 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
AU2013328580B2
(en)
|
2012-10-12 |
2016-01-21 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2014057114A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
|
HUE042731T2
(hu)
|
2012-10-12 |
2019-07-29 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin-antitest konjugátumok
|
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
AU2013328628B2
(en)
|
2012-10-12 |
2016-12-15 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-anti-CD22 antibody conjugates
|
|
AU2013328673B2
(en)
|
2012-10-12 |
2017-07-13 |
Medimmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
|
EP2922818B1
(en)
|
2012-11-24 |
2018-09-05 |
Hangzhou Dac Biotech Co., Ltd |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
|
EP2935268B2
(en)
*
|
2012-12-21 |
2021-02-17 |
MedImmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
JP6527466B2
(ja)
|
2012-12-21 |
2019-06-05 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
増殖性疾患および自己免疫疾患の治療に使用するための非対称ピロロベンゾジアゼピンニ量体
|
|
LT2958944T
(lt)
|
2013-02-22 |
2019-07-10 |
Abbvie Stemcentrx Llc |
Antikūno prieš dll3 ir pbd konjugatai bei jų panaudojimas
|
|
CN105209077B
(zh)
|
2013-03-13 |
2019-06-11 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓以及其结合物
|
|
MX364330B
(es)
|
2013-03-13 |
2019-04-23 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas.
|
|
AR096287A1
(es)
|
2013-03-13 |
2015-12-23 |
Spirogen Sàrl |
Pirrolobenzodiacepinas y conjugados
|
|
PE20151672A1
(es)
|
2013-03-14 |
2015-11-27 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-b7-h4
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
MX2016001862A
(es)
|
2013-08-12 |
2016-08-03 |
Genentech Inc |
Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo[e]indol, y metodos de uso y tratamiento.
|
|
BR112016004242A8
(pt)
|
2013-08-28 |
2018-06-12 |
Stemcentrx Inc |
Métodos para conjugação sítio-específica de anticorpos e composições
|
|
CN105792836A
(zh)
|
2013-08-28 |
2016-07-20 |
施特姆森特克斯股份有限公司 |
新型sez6调节剂以及应用方法
|
|
EA201600252A1
(ru)
|
2013-09-12 |
2017-05-31 |
Галозим, Инк. |
Модифицированные антитела к рецепторам антиэпидермального фактора роста и способы их использования
|
|
HK1218124A1
(zh)
|
2013-09-17 |
2017-02-03 |
豪夫迈．罗氏有限公司 |
使用抗lgr5抗体的方法
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
BR112016010169A2
(pt)
|
2013-11-06 |
2017-12-05 |
Stemcentrx Inc |
anticorpos anticlaudina e métodos de uso
|
|
CN115504924A
(zh)
|
2013-11-27 |
2022-12-23 |
雷德伍德生物科技股份有限公司 |
肼基-吡咯并化合物及用于生成缀合物的方法
|
|
PE20160993A1
(es)
|
2013-12-12 |
2016-10-14 |
Abbvie Stemcentrx Llc |
Nuevos anticuerpos anti-dpep3 y metodos de uso
|
|
SG11201604784XA
(en)
|
2013-12-13 |
2016-07-28 |
Genentech Inc |
Anti-cd33 antibodies and immunoconjugates
|
|
BR112016013258A2
(pt)
|
2013-12-16 |
2018-01-16 |
Genentech Inc |
composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit
|
|
CN106550593A
(zh)
|
2014-02-21 |
2017-03-29 |
艾伯维施特姆森特克斯有限责任公司 |
用于黑素瘤的抗‑dll3抗体和药物缀合物
|
|
WO2015127685A1
(en)
|
2014-02-28 |
2015-09-03 |
Hangzhou Dac Biotech Co., Ltd |
Charged linkers and their uses for conjugation
|
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
|
KR20170003582A
(ko)
|
2014-05-22 |
2017-01-09 |
제넨테크, 인크. |
항-gpc3 항체 및 면역접합체
|
|
KR102818922B1
(ko)
|
2014-08-28 |
2025-06-11 |
바이오아트라, 인코퍼레이티드 |
변형된 t 세포에 대한 조건부 활성 키메라 항원 수용체
|
|
SG11201701455SA
(en)
|
2014-09-03 |
2017-03-30 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
WO2016036804A1
(en)
|
2014-09-03 |
2016-03-10 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗ｍｆｉ２抗體及使用方法
|
|
EP3193940A1
(en)
|
2014-09-10 |
2017-07-26 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
PE20170670A1
(es)
|
2014-09-12 |
2017-06-06 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CN106804108B
(zh)
|
2014-09-12 |
2021-08-10 |
基因泰克公司 |
抗-b7-h4抗体及免疫缀合物
|
|
SG11201701128YA
(en)
|
2014-09-12 |
2017-03-30 |
Genentech Inc |
Cysteine engineered antibodies and conjugates
|
|
SG11201701623UA
(en)
|
2014-09-12 |
2017-03-30 |
Genentech Inc |
Anti-her2 antibodies and immunoconjugates
|
|
CA2957148A1
(en)
|
2014-09-17 |
2016-03-24 |
Genentech, Inc. |
Immunoconjugates comprising anti-her2 antibodies and pyrrolobenzodiazepines
|
|
US10780096B2
(en)
|
2014-11-25 |
2020-09-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
KR102693806B1
(ko)
|
2014-12-11 |
2024-08-09 |
피에르 파브르 메디카먼트 |
항-c10orf54 항체들 및 그들의 용도들
|
|
ES2747386T3
(es)
|
2015-01-14 |
2020-03-10 |
Bristol Myers Squibb Co |
Dímeros de benzodiacepina unidos por heteroarileno, conjugados de los mismos y métodos de preparación y uso
|
|
BR112017014599A2
(pt)
|
2015-01-14 |
2018-01-16 |
Bristol-Myers Squibb Company |
dímeros de benzodiazepina, conjugados dos mesmos, e métodos de preparação e uso
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201510010D0
(en)
|
2015-06-09 |
2015-07-22 |
King S College London |
PDD and BPD compounds
|
|
CN108026123B
(zh)
|
2015-06-15 |
2021-02-05 |
杭州多禧生物科技有限公司 |
用于偶联的亲水链接体
|
|
AU2016284340A1
(en)
|
2015-06-23 |
2018-02-08 |
Bristol-Myers Squibb Company |
Macrocyclic benzodiazepine dimers, conjugates thereof, preparation and uses
|
|
CA2991973C
(en)
|
2015-07-12 |
2021-12-07 |
Suzhou M-Conj Biotech Co., Ltd. |
Bridge linkers for conjugation of a cell-binding molecule
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
AU2016297087B2
(en)
|
2015-07-21 |
2021-02-18 |
Immunogen, Inc |
Methods of preparing cytotoxic benzodiazepine derivatives
|
|
US20180339985A1
(en)
|
2015-08-21 |
2018-11-29 |
Femtogenix Limited |
Pdd compounds
|
|
GB201514928D0
(en)
|
2015-08-21 |
2015-10-07 |
King S College London |
PDD compounds
|
|
EP4477269A3
(en)
|
2015-09-20 |
2025-03-19 |
The United States of America, as Represented By the Secretary, Department of Health and Human Services |
Monoclonal antibodies specific for fibroblast growth factor receptor 4 (fgfr4) and methods of their use
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
US12102689B2
(en)
|
2015-11-09 |
2024-10-01 |
R.P. Scherer Technologies, Llc |
Anti-CD22 antibody-maytansine conjugates and methods of use thereof
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
JP6735355B2
(ja)
|
2016-04-15 |
2020-08-05 |
バイオアトラ、エルエルシー |
抗Ａｘｌ抗体、抗体断片およびそれらの免疫コンジュゲートならびにそれらの使用
|
|
TW201805309A
(zh)
|
2016-04-21 |
2018-02-16 |
艾伯維史坦森特瑞斯有限責任公司 |
新穎抗－bmpr1b抗體及使用方法
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
|
TW201808336A
(zh)
|
2016-05-11 |
2018-03-16 |
賽諾菲公司 |
用抗ｍｕｃ１類美登素免疫綴合物抗體治療腫瘤的治療方案
|
|
WO2017197234A1
(en)
|
2016-05-13 |
2017-11-16 |
Bioatla, Llc |
Anti-ror2 antibodies, antibody fragments, their immunoconjugates and uses thereof
|
|
WO2017205741A1
(en)
|
2016-05-27 |
2017-11-30 |
Genentech, Inc. |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
|
US11066479B2
(en)
|
2016-08-02 |
2021-07-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies targeting glypican-2 (GPC2) and use thereof
|
|
CN109963871A
(zh)
|
2016-08-05 |
2019-07-02 |
豪夫迈·罗氏有限公司 |
具有激动活性的多价及多表位抗体以及使用方法
|
|
EP3496763A1
(en)
|
2016-08-11 |
2019-06-19 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
|
US20200023072A1
(en)
|
2016-10-11 |
2020-01-23 |
Medimmune Limited |
Antibody-drug conjugates with immune-mediated therapy agents
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
KR102345175B1
(ko)
|
2016-11-14 |
2021-12-31 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
|
KR102221364B1
(ko)
|
2016-11-21 |
2021-03-04 |
쿠레아브 게엠베하 |
항-gp73 항체 및 면역접합체
|
|
FR3059550B1
(fr)
|
2016-12-01 |
2020-01-03 |
Universite De Rouen Normandie |
Traitement des troubles causes par l'alcoolisation foetale (tcaf)
|
|
WO2018119279A1
(en)
|
2016-12-21 |
2018-06-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies specific for flt3 and uses thereof
|
|
EP3544636B1
(en)
|
2017-02-08 |
2021-03-31 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
CA3059519C
(en)
*
|
2017-04-18 |
2021-03-23 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
CN110536703B
(zh)
|
2017-04-20 |
2024-07-12 |
Adc治疗有限公司 |
使用抗axl抗体-药物缀合物的组合疗法
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
CA3059472A1
(en)
|
2017-05-19 |
2018-11-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibody targeting tnfr2 for cancer immunotherapy
|
|
UA127900C2
(uk)
|
2017-06-14 |
2024-02-07 |
Ейдісі Терапьютікс Са |
Схема дозування для введення adc до cd19
|
|
CA3066953A1
(en)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
Human monoclonal antibodies specific for cd33 and methods of their use
|
|
WO2019005208A1
(en)
|
2017-06-30 |
2019-01-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
ANTIBODIES TO HUMAN MESOTHELIN AND USES IN ANTICANCER THERAPY
|
|
CN111201030B
(zh)
|
2017-07-25 |
2024-11-01 |
真和制药有限公司 |
通过阻断tim-3和其配体的相互作用治疗癌症
|
|
MX384245B
(es)
|
2017-08-18 |
2025-03-14 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina
|
|
IL273471B2
(en)
|
2017-09-29 |
2023-09-01 |
Daiichi Sankyo Co Ltd |
Conjugation of an antibody with a pyrrolobenzodiazepine derivative
|
|
JP2021502969A
(ja)
|
2017-11-14 |
2021-02-04 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
ピロロベンゾジアゼピン複合体
|
|
EP3724225A1
(en)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics, Inc. |
Anti-cct5 binding molecules and methods of use thereof
|
|
WO2019133652A1
(en)
|
2017-12-28 |
2019-07-04 |
Immunogen, Inc. |
Benzodiazepine derivatives
|
|
GB201803342D0
(en)
*
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2019224340A1
(en)
|
2018-05-25 |
2019-11-28 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
FR3081707A1
(fr)
|
2018-05-30 |
2019-12-06 |
Universite De Rouen Normandie |
Traitement des troubles neurologiques causes par l'alcoolisation foetale
|
|
EP3820903A1
(en)
|
2018-07-12 |
2021-05-19 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Affinity matured cd22-specific monoclonal antibody and uses thereof
|
|
WO2020033430A1
(en)
|
2018-08-08 |
2020-02-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
High affinity monoclonal antibodies targeting glypican-2 and uses thereof
|
|
EP3866856A1
(en)
|
2018-10-19 |
2021-08-25 |
MedImmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
CN112867510A
(zh)
|
2018-10-19 |
2021-05-28 |
免疫医疗有限公司 |
吡咯并苯并二氮杂䓬缀合物
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
AU2020206308A1
(en)
|
2019-01-08 |
2021-07-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cross-species single domain antibodies targeting mesothelin for treating solid tumors
|
|
WO2020154150A1
(en)
|
2019-01-22 |
2020-07-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
High affinity monoclonal antibodies targeting glypican-1 and methods of use
|
|
CA3127113A1
(en)
|
2019-01-30 |
2020-08-06 |
Dongxu Sun |
Anti-gal3 antibodies and uses thereof
|
|
AU2020242747B2
(en)
|
2019-03-15 |
2025-09-18 |
Medimmune Limited |
Azetidobenzodiazepine dimers and conjugates comprising them for use in the treatment of cancer
|
|
TW202102506A
(zh)
|
2019-03-29 |
2021-01-16 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
JP7690468B2
(ja)
|
2019-10-22 |
2025-06-10 |
ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
多様な固形腫瘍を処置するためのｂ７ｈ３（ｃｄ２７６）を標的とする高親和性ナノボディ
|
|
WO2021118968A1
(en)
|
2019-12-12 |
2021-06-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-drug conjugates specific for cd276 and uses thereof
|
|
KR20220156867A
(ko)
|
2020-03-19 |
2022-11-28 |
어비디티 바이오사이언시스 인크. |
안면견갑상완 근이영양증의 치료용 조성물 및 방법
|
|
EP4126066B1
(en)
|
2020-03-27 |
2025-11-19 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle dystrophy
|
|
JP2023528797A
(ja)
|
2020-05-26 |
2023-07-06 |
トゥルーバインディング，インコーポレイテッド |
ガレクチン－３を遮断することにより炎症性疾患を処置する方法
|
|
US20230391852A1
(en)
|
2020-10-26 |
2023-12-07 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting sars coronavirus spike protein and uses thereof
|
|
US20240218055A1
(en)
|
2021-04-29 |
2024-07-04 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Lassa virus-specific nanobodies and methods of their use
|
|
US20240270851A1
(en)
|
2021-06-09 |
2024-08-15 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Cross species single domain antibodies targeting pd-l1 for treating solid tumors
|
|
US20250026838A1
(en)
|
2021-07-13 |
2025-01-23 |
Truebinding, Inc. |
Methods of preventing protein aggregation
|
|
EP4401792A4
(en)
|
2021-09-16 |
2025-12-03 |
Avidity Biosciences Inc |
COMPOSITIONS AND METHODS OF TREATMENT OF FACIO-SCAPULO-HUMERAL MUSCULAR DYSTROPHY
|
|
AU2021362997A1
(en)
|
2021-11-03 |
2024-05-16 |
Hangzhou Dac Biotech Co., Ltd. |
Specific conjugation of an antibody
|
|
CN118524852A
(zh)
|
2021-11-09 |
2024-08-20 |
真和制药有限公司 |
治疗或抑制心血管疾病的方法
|
|
KR20250006932A
(ko)
|
2022-05-03 |
2025-01-13 |
제넨테크, 인크. |
항-Ly6E 항체, 면역접합체 및 이들의 용도
|
|
WO2025019228A1
(en)
|
2023-07-20 |
2025-01-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment of solid tumors
|
|
WO2025171238A1
(en)
|
2024-02-07 |
2025-08-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind the juxta-membrane region of mesothelin and uses thereof
|