JP2001520088A - エアロゾル化薬剤の送出方法と装置 - Google Patents

エアロゾル化薬剤の送出方法と装置

Info

Publication number
JP2001520088A
JP2001520088A JP2000516721A JP2000516721A JP2001520088A JP 2001520088 A JP2001520088 A JP 2001520088A JP 2000516721 A JP2000516721 A JP 2000516721A JP 2000516721 A JP2000516721 A JP 2000516721A JP 2001520088 A JP2001520088 A JP 2001520088A
Authority
JP
Japan
Prior art keywords
conduit
canister
air
wall
open end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000516721A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001520088A5 (enExample
Inventor
アーマー，トーマス・アレツクス
エバンス，ブライス・バーウイツク
モーゼン，ナヘド・モーゼン
パブコフ，リチヤード・マシユウ
シユダールカール，アチユル・エム
Original Assignee
システミツク・パルマナリイ・デリバリー・リミテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by システミツク・パルマナリイ・デリバリー・リミテツド filed Critical システミツク・パルマナリイ・デリバリー・リミテツド
Publication of JP2001520088A publication Critical patent/JP2001520088A/ja
Publication of JP2001520088A5 publication Critical patent/JP2001520088A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A61M15/0088—Inhalation chambers with variable volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0095—Preventing manual activation in absence of inhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Nozzles (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
JP2000516721A 1997-10-17 1998-10-15 エアロゾル化薬剤の送出方法と装置 Pending JP2001520088A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/954,352 1997-10-17
US08/954,352 US5954047A (en) 1997-10-17 1997-10-17 Methods and apparatus for delivering aerosolized medication
PCT/US1998/021667 WO1999020331A1 (en) 1997-10-17 1998-10-15 Method and apparatus for delivering aerosolized medication

Related Child Applications (3)

Application Number Title Priority Date Filing Date
JP2009092696A Division JP2009183734A (ja) 1997-10-17 2009-04-07 エアロゾル化薬剤の送出方法と装置
JP2010043745A Division JP5114515B2 (ja) 1997-10-17 2010-03-01 エアロゾル化薬剤の送出方法と装置
JP2011031934A Division JP5395100B2 (ja) 1997-10-17 2011-02-17 エアロゾル化薬剤の送出方法と装置

Publications (2)

Publication Number Publication Date
JP2001520088A true JP2001520088A (ja) 2001-10-30
JP2001520088A5 JP2001520088A5 (enExample) 2006-01-05

Family

ID=25495309

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2000516721A Pending JP2001520088A (ja) 1997-10-17 1998-10-15 エアロゾル化薬剤の送出方法と装置
JP2009092696A Withdrawn JP2009183734A (ja) 1997-10-17 2009-04-07 エアロゾル化薬剤の送出方法と装置
JP2010043745A Expired - Lifetime JP5114515B2 (ja) 1997-10-17 2010-03-01 エアロゾル化薬剤の送出方法と装置
JP2011031934A Expired - Lifetime JP5395100B2 (ja) 1997-10-17 2011-02-17 エアロゾル化薬剤の送出方法と装置
JP2011146003A Expired - Lifetime JP5352630B2 (ja) 1997-10-17 2011-06-30 エアロゾル流制御装置

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2009092696A Withdrawn JP2009183734A (ja) 1997-10-17 2009-04-07 エアロゾル化薬剤の送出方法と装置
JP2010043745A Expired - Lifetime JP5114515B2 (ja) 1997-10-17 2010-03-01 エアロゾル化薬剤の送出方法と装置
JP2011031934A Expired - Lifetime JP5395100B2 (ja) 1997-10-17 2011-02-17 エアロゾル化薬剤の送出方法と装置
JP2011146003A Expired - Lifetime JP5352630B2 (ja) 1997-10-17 2011-06-30 エアロゾル流制御装置

Country Status (16)

Country Link
US (3) US5954047A (enExample)
EP (3) EP0911048B1 (enExample)
JP (5) JP2001520088A (enExample)
KR (1) KR20010031187A (enExample)
CN (1) CN1285759A (enExample)
AT (2) ATE311913T1 (enExample)
AU (1) AU750459B2 (enExample)
CA (3) CA2243175C (enExample)
DE (2) DE69841603D1 (enExample)
DK (2) DK0911048T3 (enExample)
ES (2) ES2255134T3 (enExample)
MX (1) MXPA00003766A (enExample)
NO (1) NO983631L (enExample)
NZ (1) NZ504021A (enExample)
TR (1) TR200001033T2 (enExample)
WO (1) WO1999020331A1 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003513763A (ja) * 1999-11-01 2003-04-15 システミツク・パルマナリイ・デリバリー・リミテツド 吸入装置のための内部渦機構
JP2008161696A (ja) * 2005-01-25 2008-07-17 Valois Sas 流体ディスペンサ装置
JP2008295685A (ja) * 2007-05-30 2008-12-11 Yoshino Kogyosho Co Ltd 吸引式投薬器
JP2011504387A (ja) * 2007-11-22 2011-02-10 ジークフリート・ジェネリクス・インターナショナル・アクチェンゲゼルシャフト 粉末物質の吸入のための計量装置
JP2012232183A (ja) * 2006-02-17 2012-11-29 Sanofi Sa 分散装置
KR101261231B1 (ko) * 2004-10-15 2013-05-07 씨아이피엘에이 엘티디. 개량된 스페이서
JP2013515577A (ja) * 2009-12-23 2013-05-09 マップ ファーマシューティカルズ， インコーポレイテッド 強化排出装置設計
JP2015526226A (ja) * 2012-08-28 2015-09-10 カインド・コンシューマー・リミテッドＫｉｎｄ Ｃｏｎｓｕｍｅｒ Ｌｉｍｉｔｅｄ プルームに空気ジェットが衝突する呼吸作動式吸入器
JP2019513477A (ja) * 2016-04-15 2019-05-30 アプター フランス エスアーエス 吸気同期式の流体吐出装置
JP2019513478A (ja) * 2016-04-15 2019-05-30 アプター フランス エスアーエス 吸気同期式の流体吐出装置
JP2021526945A (ja) * 2018-06-04 2021-10-11 トゥルーデル メディカル インターナショナル 陽気圧治療装置、そのキット、並びに使用法及び組み立て法

Families Citing this family (243)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6703050B1 (en) * 1998-09-04 2004-03-09 The Regents Of The University Of Michigan Methods and compositions for the prevention or treatment of cancer
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6257231B1 (en) * 1998-12-03 2001-07-10 Ferraris Medical, Inc. Aerosol enhancement
ZA9811257B (en) * 1998-12-09 2001-01-31 App Sub Cipla Ltd 8 8 2000 Inhalation device.
CA2377566C (en) * 1999-05-20 2007-08-07 Iep Pharmaceutical Devices, Inc. Low spray force, low retention atomization system
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
CA2383058A1 (en) * 1999-09-13 2001-05-31 Nahed Mohsen Aerosol airflow control system and method
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
GB0002798D0 (en) * 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
CA2401288A1 (en) 2000-02-28 2001-09-07 Vectura Limited Improvements in or relating to the delivery of oral drugs
US6443151B1 (en) 2000-03-08 2002-09-03 Aradigm Corporation Fluid velocity-sensitive trigger mechanism
GB2360216A (en) * 2000-03-18 2001-09-19 Astrazeneca Uk Ltd Inhaler
PT1142601E (pt) * 2000-04-07 2006-05-31 Andi Ventis Ltd Bocal para inalador de particulas
WO2001076671A2 (en) 2000-04-11 2001-10-18 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
US6328035B1 (en) * 2000-05-09 2001-12-11 Iep Pharmaceutical Devices Inc. Pneumatic breath actuated inhaler
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
HRP20021025B1 (hr) * 2000-05-22 2013-11-22 Chiesi Farmaceutici S.P.A. Formulacije stabilnih farmaceutskih otopina za inhalatore s odmjerenom dozom pod tlakom
TWI224511B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd De-agglomerator for breath-actuated dry powder inhaler
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
SE517226C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator med luftbroms för torrt pulver
GB0023845D0 (en) * 2000-09-29 2000-11-15 Pa Knowledge Ltd Dosing device
US7093594B2 (en) * 2000-09-29 2006-08-22 Pfizer Limited Dosing device
EP1935869A1 (en) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
US6964647B1 (en) * 2000-10-06 2005-11-15 Ellaz Babaev Nozzle for ultrasound wound treatment
US6601581B1 (en) 2000-11-01 2003-08-05 Advanced Medical Applications, Inc. Method and device for ultrasound drug delivery
US6761729B2 (en) 2000-12-22 2004-07-13 Advanced Medicalapplications, Inc. Wound treatment method and device with combination of ultrasound and laser energy
US6533803B2 (en) 2000-12-22 2003-03-18 Advanced Medical Applications, Inc. Wound treatment method and device with combination of ultrasound and laser energy
US7914470B2 (en) * 2001-01-12 2011-03-29 Celleration, Inc. Ultrasonic method and device for wound treatment
US8235919B2 (en) 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
US6960173B2 (en) * 2001-01-30 2005-11-01 Eilaz Babaev Ultrasound wound treatment method and device using standing waves
US6623444B2 (en) 2001-03-21 2003-09-23 Advanced Medical Applications, Inc. Ultrasonic catheter drug delivery method and device
SE518397C2 (sv) * 2001-04-05 2002-10-01 Microdrug Ag Förfarande och anordning för frigörande av pulver och inhalatoranordning för administrering av medicinskt pulver
US6478754B1 (en) 2001-04-23 2002-11-12 Advanced Medical Applications, Inc. Ultrasonic method and device for wound treatment
WO2002088841A1 (en) 2001-04-25 2002-11-07 Matsushita Electric Industrial Co., Ltd. Projection display device
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US6681768B2 (en) * 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
ES2222294T3 (es) * 2001-07-02 2005-02-01 Chiesi Farmaceutici S.P.A. Formulacion optimizada de tobramicina para administracion en forma de aerosol.
US7343914B2 (en) * 2001-09-06 2008-03-18 Microdose Technologies, Inc. Adaptors for inhalers to improve performance
AU2002340083A1 (en) 2001-09-28 2003-04-07 Kurve Technology, Inc Nasal nebulizer
US6701922B2 (en) * 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
LT3494995T (lt) * 2002-03-01 2020-04-10 Chiesi Farmaceutici S.P.A. Ypatingai smulki formoterolio kompozicija
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
GB0209494D0 (en) * 2002-04-25 2002-06-05 Optinose As Nasal devices
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
AU2003225071A1 (en) * 2002-05-03 2003-11-17 Trudell Medical International Aerosol medication delivery apparatus with narrow orifice
WO2003099359A1 (en) * 2002-05-09 2003-12-04 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
US7118010B2 (en) 2002-05-10 2006-10-10 Oriel Therapeutics, Inc. Apparatus, systems and related methods for dispensing and /or evaluating dry powders
US6889690B2 (en) * 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US7677411B2 (en) 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
US6985798B2 (en) 2002-05-10 2006-01-10 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
JP4243499B2 (ja) * 2002-06-11 2009-03-25 富士通株式会社 貼合せ基板製造装置及び貼合せ基板製造方法
AU2003258985B2 (en) * 2002-06-27 2008-07-03 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
US7189865B2 (en) * 2002-07-23 2007-03-13 Attenuon, Llc Thiomolybdate analogues and uses thereof
MXPA05000875A (es) 2002-07-23 2005-09-30 Univ Michigan Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas.
ATE491521T1 (de) * 2002-09-06 2011-01-15 Philip Morris Usa Inc Aerosolerzeugungsvorrichtungen und verfahren zur erzeugung von aerosolen mit gesteuerten teilchengrössen
US20060135463A1 (en) * 2002-09-27 2006-06-22 Wood Christopher B Methods and compositions for the treatment of lupus using clofarabine
AU2003276988B2 (en) * 2002-09-27 2009-11-05 Bioenvision, Inc. Methods and compositions for the treatment of autoimmune disorders using clofarabine
US6834717B2 (en) 2002-10-04 2004-12-28 R&M Energy Systems, Inc. Tubing rotator
AU2003282534A1 (en) * 2002-10-07 2004-05-04 Radiorx, Inc. X-nitro compounds, pharmaceutical compositions thereof and uses therof
AU2003285109A1 (en) * 2002-10-30 2004-06-07 Glaxo Group Limited Tubular nozzles for use in systems for delivering medicaments
MXPA05005469A (es) * 2002-11-25 2005-09-08 Attenuon Llc Peptidos que inhibien angiogenesis, migracion celular, invasion celular y proliferacion celular, composiciones y usos de los mismos.
EP1575648A4 (en) * 2002-12-18 2007-07-04 Glaxo Group Ltd DRUG DELIVERY SYSTEM WITH A VENTILATED MOUTHPIECE
WO2004064705A2 (en) * 2003-01-17 2004-08-05 Schering Corporation Training device for medicament inhalers
ZA200504940B (en) * 2003-01-28 2006-09-27 Xenoport Inc Amino acid derived prodrugs of propofol, compositions and uses thereof
BRPI0408223A (pt) 2003-03-12 2006-03-01 Celgene Corp composto, isÈmeros, composição farmacêutica, e, métodos de inibir pde4 e mmp, de modular a produção de tnf-alfa em um mamìfero e de tratar, previnir ou controlar uma doença ou condição
PL2910551T3 (pl) 2003-04-11 2017-09-29 Ptc Therapeutics, Inc. Związki kwasu 1,2,4-oksadiazolobenzoesowego i ich zastosowanie do supresji mutacji nonsensownych i leczenia choroby
US7360537B2 (en) * 2003-04-16 2008-04-22 Trudell Medical International Antistatic medication delivery apparatus
EP1633310A4 (en) * 2003-05-27 2006-10-18 Attenuon Llc THIOWOLFRAM ANALOGUE AND ITS USES
US20050009782A1 (en) * 2003-07-09 2005-01-13 Comper Wayne D. Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof
WO2005023334A2 (en) * 2003-09-05 2005-03-17 Kurve Technology, Inc. Nasal adapter for the base of the nose
EP1673123A2 (en) * 2003-09-05 2006-06-28 Kurve Technology, Inc. Integrated nebulizer and particle dispersing chamber for delivery of medicament
US7230003B2 (en) * 2003-09-09 2007-06-12 Xenoport, Inc. Aromatic prodrugs of propofol, compositions and uses thereof
CA2538237A1 (en) * 2003-09-10 2005-03-24 Map Pharmaceuticals, Inc. Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
GB2405799A (en) * 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler incorporating a valve which is opened and closed by pressurized gas
US7342660B2 (en) * 2003-09-25 2008-03-11 Deka Products Limited Partnership Detection system and method for aerosol delivery
US7066029B2 (en) * 2003-09-25 2006-06-27 Deka Products Limited Partnership System and method for improved volume measurement
US7451761B2 (en) 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
US7377277B2 (en) 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
EP1692128A1 (en) 2003-11-19 2006-08-23 Signal Pharmaceuticals LLC Indazole compounds and methods of use thereof as protein kinase inhibitors
EP1729784A1 (en) * 2004-02-23 2006-12-13 Attenuon, LLC Formulations of thiomolybdate or thiotungstate compounds and uses thereof
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
EP1730751B1 (en) * 2004-03-12 2009-10-21 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin A magnetoresistive medium
US7448385B2 (en) * 2004-06-07 2008-11-11 Purepharm Inc. Nasal adaptation of an oral inhaler device
WO2006017351A1 (en) * 2004-07-12 2006-02-16 Xenoport, Inc. Prodrugs of propofol, compositions and uses thereof
ES2315897T3 (es) * 2004-07-12 2009-04-01 Xenoport, Inc. Aminoacidos derivados de porfarmacos de composiciones de propofol y usos del mismo.
US20060128676A1 (en) * 2004-07-13 2006-06-15 Pharmacofore, Inc. Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
CN101010305B (zh) 2004-08-20 2010-08-11 曼金德公司 二酮哌嗪合成的催化反应
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
WO2006031775A2 (en) * 2004-09-13 2006-03-23 Oriel Therapeutics, Inc. Dry powder inhalers that inhibit agglomeration, related devices and methods
US7425552B2 (en) * 2004-12-17 2008-09-16 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
ES2459368T3 (es) 2004-12-17 2014-05-09 Anadys Pharmaceuticals, Inc. Compuestos de 3H-oxazolo y 3H-tiazolo[4,5-d]pirimidin-2-ona 3,5-disustituidos y 3,5,7-trisustituidos y profármacos de los mismos
DE602005019210D1 (de) * 2004-12-23 2010-03-18 Xenoport Inc Von serinaminosäure abgeleitete prodrugs von propofol, zusammensetzungen, anwendungen und kristalline formen davon
US7785277B2 (en) 2005-06-23 2010-08-31 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
US7713218B2 (en) 2005-06-23 2010-05-11 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
AU2006272922A1 (en) 2005-07-22 2007-02-01 Amgen Inc. Aniline sulfonamide derivatives and their uses
US20070135380A1 (en) 2005-08-12 2007-06-14 Radiorx, Inc. O-nitro compounds, pharmaceutical compositions thereof and uses thereof
US7507842B2 (en) 2005-08-12 2009-03-24 Radiorx, Inc. Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof
EP1928881A2 (en) 2005-08-19 2008-06-11 Pharmacofore, Inc. Prodrugs of active agents
KR101384456B1 (ko) 2005-09-14 2014-04-10 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
DE102005054383B4 (de) * 2005-11-15 2013-10-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Nadel zum Lochen von Pulverkapseln für die Inhalation
US20070249572A1 (en) * 2005-12-20 2007-10-25 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070160542A1 (en) * 2005-12-20 2007-07-12 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070197486A1 (en) * 2005-12-20 2007-08-23 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids
US20070178049A1 (en) * 2005-12-20 2007-08-02 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070185066A1 (en) * 2005-12-20 2007-08-09 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
CA2641574C (en) 2006-02-09 2015-05-05 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
EP1988878A2 (en) * 2006-02-15 2008-11-12 Tika Läkemedel AB Sterilization of corticosteroids with reduced mass loss
AU2013205495B2 (en) * 2006-02-17 2015-11-26 Sanofi Sa Dispersing unit
GB2433207B (en) * 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
EP2004619A1 (en) * 2006-03-23 2008-12-24 Amgen Inc. 1-phenylsulfonyl-diaza heterocyclic amide compounds and their uses as modulators of hydroxsteroid dehydrogenases
DK2046393T3 (da) 2006-05-26 2014-05-12 Signature Therapeutics Inc Kontrolleret frigivelse af phenol-opioider
US7431704B2 (en) * 2006-06-07 2008-10-07 Bacoustics, Llc Apparatus and method for the treatment of tissue with ultrasound energy by direct contact
US8562547B2 (en) 2006-06-07 2013-10-22 Eliaz Babaev Method for debriding wounds
EP2029540B1 (en) * 2006-06-08 2010-08-04 Amgen Inc. Benzamide derivatives and uses related thereto
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
JP5306194B2 (ja) 2006-06-22 2013-10-02 アナディス ファーマシューティカルズ インク ピロ［１，２−ｂ］ピリダジノン化合物
ATE496924T1 (de) 2006-06-22 2011-02-15 Anadys Pharmaceuticals Inc Prodrugs von 5-amino-3-(3'-deoxy-beta-d- ribofuranosyl)-thiazolä4,5-düpyrimidin-2,7-dion
WO2008051637A2 (en) * 2006-06-22 2008-05-02 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
EP2037999B1 (en) 2006-07-07 2016-12-28 Proteus Digital Health, Inc. Smart parenteral administration system
BRPI0714831A2 (pt) 2006-07-18 2013-04-02 Anadys Pharmaceuticals Inc composto, composiÇço farmacÊutica e mÉtodos de modulaÇço de atividades imuno da citoquina em paciente, de tratamento de infecÇço de vÍrus c da hepatite em paciente e de desordem relacionada com proliferaÇço em mamÍfero necessitado do mesmo
AU2007275301A1 (en) * 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1
EP2106268B1 (en) 2006-08-30 2018-12-12 Kurve Technology, Inc. Aerosol generating and delivery device
BRPI0603695A (pt) * 2006-09-13 2008-04-29 Cesar Eduardo Marques Da Silva aerocámara para aplicação de medicamentos aerossol com válvula geométrica
US20080087279A1 (en) * 2006-10-11 2008-04-17 Tieck Catharine Laureen Johnso Metered dose inhaler
US20080177221A1 (en) * 2006-12-22 2008-07-24 Celleration, Inc. Apparatus to prevent applicator re-use
CA2673586A1 (en) * 2006-12-26 2008-07-24 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
WO2008082725A1 (en) * 2006-12-29 2008-07-10 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
US8491521B2 (en) 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
US20080214965A1 (en) * 2007-01-04 2008-09-04 Celleration, Inc. Removable multi-channel applicator nozzle
ES2691033T3 (es) * 2007-02-11 2018-11-23 Map Pharmaceuticals Inc. Método de administración terapéutica de DHE para activar el alivio rápido de la migraña a la vez que se reduce al mínimo el perfil de los efectos secundarios
SI2129422T1 (sl) * 2007-02-27 2013-11-29 Ivax Pharmaceuticals Ireland Dozirni inhalator
US20080306076A1 (en) * 2007-06-08 2008-12-11 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) * 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US9603848B2 (en) * 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
WO2011163272A1 (en) 2010-06-21 2011-12-29 Mannkind Corporation Dry powder drug delivery system and methods
JP5243548B2 (ja) 2007-10-25 2013-07-24 プロテウス デジタル ヘルス， インコーポレイテッド 情報システムのための流体伝達ポート
GB2454742B (en) * 2007-11-17 2011-02-02 David Ohayon Inhaler adapter
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
JP5570996B2 (ja) 2007-12-14 2014-08-13 エアロデザインズ インコーポレイテッド エアロゾル化可能な食料品の送達
US20090177122A1 (en) * 2007-12-28 2009-07-09 Celleration, Inc. Methods for treating inflammatory skin disorders
US20090177123A1 (en) * 2007-12-28 2009-07-09 Celleration, Inc. Methods for treating inflammatory disorders
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2293833T3 (en) 2008-06-13 2016-05-23 Mannkind Corp DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
US8517009B2 (en) 2008-07-13 2013-08-27 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
US20100022919A1 (en) * 2008-07-22 2010-01-28 Celleration, Inc. Methods of Skin Grafting Using Ultrasound
UA113831C2 (xx) 2008-07-31 2017-03-27 Способи і проміжні сполуки для одержання підсилювачів солодкого смаку
RU2511315C2 (ru) 2008-07-31 2014-04-10 Синомикс, Инк. Композиции, содержащие усилители сладкого вкуса, и способы их получения
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US20110229438A1 (en) 2008-10-09 2011-09-22 Anadys Pharmaceuticals, Inc. Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
WO2010065547A1 (en) * 2008-12-01 2010-06-10 Map Pharmaceuticals, Inc. Inhalation delivery methods and devices
WO2010074753A1 (en) 2008-12-23 2010-07-01 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
US8495998B2 (en) * 2009-06-17 2013-07-30 British American Tobacco (Investments) Limited Inhaler
US20110171141A1 (en) * 2009-06-26 2011-07-14 Kellerman Donald J Administration of dihydroergotamine mesylate particles using a metered dose inhaler
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
MX2012005711A (es) * 2009-11-17 2012-10-05 Cipla Ltd Soluciones de inhalacion.
MY169700A (en) 2010-02-01 2019-05-13 Proteus Digital Health Inc Data gathering system
RU2587795C2 (ru) 2010-02-01 2016-06-20 Проутьюс Диджитал Хэлс, Инк. Система сбора данных
US8471041B2 (en) * 2010-02-09 2013-06-25 Alliant Techsystems Inc. Methods of synthesizing and isolating N-(bromoacetyl)-3,3-dinitroazetidine and a composition including the same
EP2824111B1 (en) 2010-04-30 2017-03-22 Alexion Pharmaceuticals, Inc. Anti-C5A Antibodies and Methods for Using the Antibodies
DE102010024912B4 (de) * 2010-06-15 2013-02-28 Aptar Radolfzell Gmbh Inhalationsvorrichtung
CN103249432A (zh) 2010-06-22 2013-08-14 科罗拉多大学董事会,法人团体 补体成分3的C3d片段的抗体
EP2603098B1 (en) 2010-08-12 2025-08-06 Firmenich Incorporated Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
ES2625858T3 (es) 2011-04-01 2017-07-20 Mannkind Corporation Paquete de tipo blíster para cartuchos farmacéuticos
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US8664247B2 (en) 2011-08-26 2014-03-04 Radiorx, Inc. Acyclic organonitro compounds for use in treating cancer
EP2763667B1 (en) 2011-10-07 2022-10-26 EpicentRx, Inc. Organonitro thioether compounds and medical uses thereof
WO2013052803A2 (en) 2011-10-07 2013-04-11 Radiorx, Inc. Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products
HK1201475A1 (en) 2011-10-24 2015-09-04 Mannkind Corporation Methods and compositions for treating pain
US9603906B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Inhalable liquid formulations of DNase I
ES2690398T3 (es) 2012-03-07 2018-11-20 Advanced Inhalation Therapies (Ait) Ltd. Inhalación de óxido nítrico para el tratamiento de enfermedades respiratorias
CA3098386C (en) 2012-07-12 2022-11-29 Mannkind Corporation Dry powder drug delivery systems and methods
KR20200028050A (ko) 2012-08-06 2020-03-13 피르메니히 인코포레이티드 단맛 향미 개질제
US9713687B2 (en) * 2012-08-21 2017-07-25 Philip Morris Usa Inc. Ventilator aerosol delivery system with transition adapter for introducing carrier gas
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
MX369136B (es) 2013-03-15 2019-10-30 Mannkind Corp Composiciones de dicetopiperazina microcristalina y metodos.
BR122019026637B1 (pt) 2013-07-18 2023-09-26 Mannkind Corporation Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US11224767B2 (en) 2013-11-26 2022-01-18 Sanuwave Health, Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
GB2524469A (en) * 2014-02-14 2015-09-30 Kind Consumer Ltd A cannabinoid inhaler and composition therefor
NZ711451A (en) 2014-03-07 2016-05-27 Alexion Pharma Inc Anti-c5 antibodies having improved pharmacokinetics
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561809B2 (en) * 2014-06-06 2020-02-18 Rijksuniversiteit Groningen Breath actuated dry powder inhaler
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016057693A1 (en) 2014-10-10 2016-04-14 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
BR112018001018B1 (pt) * 2015-07-20 2022-07-19 Pearl Therapeutics, Inc Unidade de liberação de aerossol
CN105092786A (zh) * 2015-07-23 2015-11-25 上海化工研究院 一种对冲式定量雾化给药装置
GB2556817B (en) 2015-10-01 2019-11-06 Elysium Therapeutics Inc Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
US10342778B1 (en) 2015-10-20 2019-07-09 Epicentrx, Inc. Treatment of brain metastases using organonitro compound combination therapy
US9987270B1 (en) 2015-10-29 2018-06-05 Epicentrix, Inc. Treatment of gliomas using organonitro compound combination therapy
WO2017112451A1 (en) 2015-12-21 2017-06-29 3M Innovative Properties Company Auto-reset dose release firing systems, medicinal inhalers comprising same, and methods of using same
WO2017112400A1 (en) 2015-12-21 2017-06-29 3M Innovative Properties Company Medicinal inhalers
US11071837B2 (en) 2015-12-21 2021-07-27 Kindeva Drug Delivery L.P. Dose release firing systems and medicinal inhalers comprising same
AU2017207304B2 (en) 2016-01-11 2022-05-26 Epicentrx, Inc. Compositions and methods for intravenous administration of 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone
CN109475630A (zh) 2016-05-27 2019-03-15 瑞颂医药公司 治疗难治性全身型重症肌无力的方法
WO2018064825A1 (zh) * 2016-10-09 2018-04-12 益得生物科技股份有限公司 药物传递装置及其系统
CA3040479A1 (en) 2016-10-14 2018-04-19 Epicentrx, Inc. Sulfoxyalkyl organonitro and related compounds and pharmaceutical compositions for use in medicine
CA3056239C (en) 2017-03-17 2023-09-12 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
IL311727A (en) 2017-07-07 2024-05-01 Epicentrx Inc Preparations for intravenous administration of medical substances
PT3658184T (pt) 2017-07-27 2023-11-29 Alexion Pharma Inc Formulações de anticorpo anti-c5 de elevada concentração
CN109481802B (zh) * 2017-09-12 2024-09-24 张海飞 全自动定量气雾吸入装置
BR112020008182A2 (pt) 2017-10-26 2020-10-27 Alexion Pharmaceuticals, Inc. dosagem e administração de anticorpos anti-c5 para tratamento de hemoglobinúria paroxística noturna (hpn) e síndrome hemolítica urêmica atípica (shua)
IL255520A0 (en) * 2017-11-08 2017-12-31 Omrix Biopharmaceuticals Ltd Powder release device
WO2019164593A2 (en) 2018-01-08 2019-08-29 Epicentrx, Inc. Methods and compositions utilizing rrx-001 combination therapy for radioprotection
CN111587133B (zh) * 2018-01-23 2023-03-10 艾斯曲尔医疗公司 气雾剂发生器
EP3773614A1 (en) 2018-04-12 2021-02-17 Matrx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown
JP7520725B2 (ja) 2018-05-31 2024-07-23 アレクシオン ファーマシューティカルズ， インコーポレイテッド 小児患者における発作性夜間ヘモグロビン尿症（ｐｎｈ）の治療のための抗ｃ５抗体の用量および投与
US12460012B2 (en) 2018-06-04 2025-11-04 Alexion Pharmaceuticals, Inc. Dosage and administration of anti-C5 antibodies for treatment of atypical hemolytic uremic syndrome (aHUS) in pediatric patients
EP3814373A1 (en) 2018-06-28 2021-05-05 Alexion Pharmaceuticals, Inc. Methods of producing anti-c5 antibodies
CN109078234A (zh) * 2018-07-03 2018-12-25 李骏达 用于慢性伤口清创的局部组织闭合涡流冲洗器
EP3814344B1 (en) 2018-08-07 2024-07-24 Firmenich Incorporated 5-substituted 4-amino-1h-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof
US12240893B2 (en) 2018-10-30 2025-03-04 Alexion Pharmaceuticals, Inc. Subcutaneous dosage and administration of anti-C5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (PNH)
JP7250317B2 (ja) * 2019-03-18 2023-04-03 学校法人日本大学 薬剤吸入器
NL2023033B1 (en) * 2019-04-30 2020-11-23 Medspray B V Spray inhaler device
KR20220039657A (ko) * 2019-05-24 2022-03-29 블루 오션 그룹 엘엘씨 정량식 분무흡입기용 소형 스페이서
KR102200764B1 (ko) * 2020-02-18 2021-01-08 가톨릭대학교 산학협력단 마취용 기화기의 마취액용기 가압유지장치
CN111359060A (zh) * 2020-02-20 2020-07-03 深圳麦克韦尔科技有限公司 雾化吸嘴及雾化装置
CN111214737B (zh) * 2020-03-06 2020-10-20 张洁 一种儿童用雾化器
CN111544715B (zh) * 2020-04-02 2022-08-19 佛山市澳斯卡医疗器械有限公司 一种瓶装雾化器
CN111536555A (zh) * 2020-05-08 2020-08-14 中国航发湖南动力机械研究所 发动机及其发动机燃烧室
US11925749B2 (en) * 2021-03-18 2024-03-12 Funai Electric Co., Ltd. Venting of pharmaceutical drug delivery device for air flow and humidity control
CN115120819B (zh) * 2021-03-24 2024-02-09 心诚镁行动医电股份有限公司 雾化装置以及喷嘴模块
KR102682149B1 (ko) * 2022-03-15 2024-07-05 주식회사 이엠텍 액상의 점성 변화에 의해 분무되는 에어로졸 발생 장치
WO2023178283A1 (en) 2022-03-18 2023-09-21 Epicentrx, Inc. Co-crystals of 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone and methods
WO2023215227A1 (en) 2022-05-02 2023-11-09 Epicentrx, Inc. Systems and methods to improve exercise tolerance
WO2023215229A1 (en) 2022-05-02 2023-11-09 Epicentrx, Inc. Compositions and methods for treatment of pulmonary hypertension
TW202408485A (zh) 2022-06-13 2024-03-01 美商埃皮辛特瑞科斯公司 用於減少癌症治療中不良副作用之組合物及方法
WO2024098009A1 (en) 2022-11-04 2024-05-10 Epicentrx, Inc. Rrx-001 for minimizing post-infarct adverse ventricular remodeling and complications
WO2024124152A1 (en) 2022-12-08 2024-06-13 Epicentrx, Inc. Rrx-001 for the treatment of a hemoglobinopathy
CN116510139B (zh) * 2023-04-04 2025-12-12 深圳雾芯科技有限公司 用于吸入器的测速装置及具有其的吸入器套装

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3838686A (en) * 1971-10-14 1974-10-01 G Szekely Aerosol apparatus for inhalation therapy
JPS62221366A (ja) * 1986-03-07 1987-09-29 アクチエボラゲツト・ドラコ 散薬吸入器用装置
JPS6377460A (ja) * 1986-09-22 1988-04-07 オムロン株式会社 霧化器
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
JPH0199570A (ja) * 1987-09-30 1989-04-18 Bootran Medical Technol Inc 吸入装置と吸入方法
GB2279879A (en) * 1993-07-14 1995-01-18 Bespak Plc Medicament inhalers
GB2299512A (en) * 1995-04-06 1996-10-09 Ian James Sharp Inhaler
JP2001506885A (ja) * 1996-12-18 2001-05-29 イノバータ・バイオミッド・リミテッド 粉末吸入器

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2305210A (en) * 1940-10-28 1942-12-15 Spraying Systems Co Spray shaper
US2751252A (en) * 1953-12-14 1956-06-19 Spraying Systems Co Whirl spray nozzle
US2984420A (en) * 1959-11-20 1961-05-16 Jr John W Hession Aerosol devices
US3072346A (en) * 1961-09-29 1963-01-08 Spraying Systems Co Spray nozzle
FR1322998A (fr) * 1962-02-23 1963-04-05 Perfectionnements aux dispositifs de production d'aérosols
US3240431A (en) * 1964-05-27 1966-03-15 Clayton Corp Of Delaware Combination valve spout and spray head assembly
US3385295A (en) * 1966-02-07 1968-05-28 Puritan Compressed Gas Corp Apparatus for use in administering intermittent positive pressure breathing therapy
US3406913A (en) * 1966-09-01 1968-10-22 Revlon Mechanical break-up actuator for fluid dispensers
US3456644A (en) * 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
GB1253221A (enExample) * 1968-04-23 1971-11-10
US3522806A (en) * 1968-08-07 1970-08-04 G S Intern Lab Corp Aerosol apparatus for inhalation therapy
DE1813993C3 (de) * 1968-12-11 1974-01-24 Paul Ritzau Pari-Werk Kg, 8135 Soecking Vorrichtung zum Zerstäuben und Vernebeln von flüssigen oder pulverförmigen Stoffen
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
US4049200A (en) * 1976-04-05 1977-09-20 Sobol Jacob M Nebulizer
DE3166709D1 (en) * 1980-08-04 1984-11-22 Fisons Plc Inhalation device for administering medicaments
DE3043377A1 (de) * 1980-11-17 1982-07-01 Brugger, Inge, 8130 Starnberg Zerstaeuber
FI69962C (fi) * 1983-12-28 1986-09-12 Huhtamaeki Oy Inhalationsanordning
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
DE8621135U1 (de) * 1985-09-02 1987-01-29 Callahan, George Edgar, Prof., 40479 Düsseldorf Sprühvorrichtung zum Aufsetzen auf einen zusammenpressbaren Behälter
GB8614805D0 (en) * 1986-06-18 1986-07-23 British American Tobacco Co Aerosol device
DE3775679D1 (de) * 1986-09-22 1992-02-13 Omron Tateisi Electronics Co Vernebler.
US4768717A (en) * 1987-02-12 1988-09-06 Specialty Packaging Licensing Company Nozzle
DE3856185D1 (de) * 1987-12-11 1998-06-18 Deutsch Zentr Luft & Raumfahrt Dralldüse zum Zerstäuben einer Flüssigkeit
DE68914932T2 (de) * 1988-10-04 1994-08-11 Univ Johns Hopkins Inhalationsgerät für Aerosolen.
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
GB8919131D0 (en) * 1989-08-23 1989-10-04 Riker Laboratories Inc Inhaler
DE8912098U1 (de) * 1989-10-11 1990-11-08 Magasi, Josef, 6902 Sandhausen Inhalator
FR2658081B1 (fr) * 1990-02-09 1995-06-30 Pesenti Yvan Dispositif d'automatisation et synchronisation des appareils aerosols a pompe doseuse.
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US5615670A (en) * 1990-03-07 1997-04-01 Fisons Plc Powder inhaler with centrifugal force used to meter powder
GB9015077D0 (en) * 1990-07-09 1990-08-29 Riker Laboratories Inc Inhaler
US5060643A (en) * 1990-08-07 1991-10-29 Tenax Corporation Breath-activated inhalation device
DE4027391A1 (de) * 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
US5178138A (en) * 1990-09-11 1993-01-12 Walstrom Dennis R Drug delivery device
GB9020555D0 (en) * 1990-09-20 1990-10-31 Bespak Plc Dispensing apparatus
US5027808A (en) * 1990-10-31 1991-07-02 Tenax Corporation Breath-activated inhalation device
US5217004A (en) * 1990-12-13 1993-06-08 Tenax Corporation Inhalation actuated dispensing apparatus
US5040527A (en) * 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
ES2179068T3 (es) * 1991-03-05 2003-01-16 Aradigm Corp Metodo y dispositivo para corregir el desplazamiento de deriva de un detector de presion de flujo.
EP0504459B1 (de) * 1991-03-21 1996-06-05 PAUL RITZAU PARI-WERK GmbH Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
ES2141108T3 (es) * 1991-07-02 2000-03-16 Inhale Inc Metodo y dispositivo para proporcionar medicamentos en aerosol.
PL169046B1 (pl) * 1991-08-29 1996-05-31 Christoph Klein Przyrzad medyczny do inhalacji aerozolem PL PL PL PL PL
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5228624A (en) * 1992-03-02 1993-07-20 Mensink Daniel L Swirling structure for mixing two concentric fluid flows at nozzle outlet
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
SE9201411D0 (sv) * 1992-05-05 1992-05-05 Astra Ab Dosage inhalator with indicating/interupting means
UA27938C2 (uk) * 1992-10-19 2000-10-16 Д'Юра Фармас'Ютікалз, Інк Пристрій для розпилення лікарського засобу у формі порошку для інгаляції
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
US5474059A (en) * 1995-04-08 1995-12-12 Cooper; Guy F. Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
US5598836A (en) * 1995-05-26 1997-02-04 Healthscan Products, Inc. Metered dose inhalation unit with slide means
US5724986A (en) * 1995-11-06 1998-03-10 Jones Medical Instrument Co. Casing and spirometer for metered dose inhaler
WO1997025086A2 (en) * 1996-01-03 1997-07-17 Glaxo Group Limited Inhalation device
US5875774A (en) * 1996-01-05 1999-03-02 Sunrise Medical Hhg Inc. Nebulizer
GB2312379B (en) * 1996-04-25 1999-11-17 Bespak Plc Improved inhalers
GB2312848B (en) * 1996-04-26 1999-11-17 Bespak Plc Controlled flow inhalers
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
US5894995A (en) * 1997-07-08 1999-04-20 Mazzei; Angelo L. Infusion nozzle imparting axial and rotational flow elements
GB2334686B (en) * 1998-02-26 2002-06-19 Medic Aid Ltd Nebuliser

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3838686A (en) * 1971-10-14 1974-10-01 G Szekely Aerosol apparatus for inhalation therapy
JPS62221366A (ja) * 1986-03-07 1987-09-29 アクチエボラゲツト・ドラコ 散薬吸入器用装置
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
JPS6377460A (ja) * 1986-09-22 1988-04-07 オムロン株式会社 霧化器
JPH0199570A (ja) * 1987-09-30 1989-04-18 Bootran Medical Technol Inc 吸入装置と吸入方法
GB2279879A (en) * 1993-07-14 1995-01-18 Bespak Plc Medicament inhalers
GB2299512A (en) * 1995-04-06 1996-10-09 Ian James Sharp Inhaler
JP2001506885A (ja) * 1996-12-18 2001-05-29 イノバータ・バイオミッド・リミテッド 粉末吸入器

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003513763A (ja) * 1999-11-01 2003-04-15 システミツク・パルマナリイ・デリバリー・リミテツド 吸入装置のための内部渦機構
KR101261231B1 (ko) * 2004-10-15 2013-05-07 씨아이피엘에이 엘티디. 개량된 스페이서
JP2008161696A (ja) * 2005-01-25 2008-07-17 Valois Sas 流体ディスペンサ装置
JP2008528156A (ja) * 2005-01-25 2008-07-31 バルワー エス．アー．エス． 流体ディスペンサ装置
JP2012232183A (ja) * 2006-02-17 2012-11-29 Sanofi Sa 分散装置
JP2008295685A (ja) * 2007-05-30 2008-12-11 Yoshino Kogyosho Co Ltd 吸引式投薬器
US8508385B2 (en) 2007-11-22 2013-08-13 Sanofi-Aventis Deutschland Gmbh Metering device for the inhalation of a pulverulent substance
JP2011504387A (ja) * 2007-11-22 2011-02-10 ジークフリート・ジェネリクス・インターナショナル・アクチェンゲゼルシャフト 粉末物質の吸入のための計量装置
US8573204B2 (en) 2007-11-22 2013-11-05 Siegfried Generics International Metering device for the inhalation of a pulverulent substance
US9895501B2 (en) 2007-11-22 2018-02-20 Sanofi-Aventis Deutschland Gmbh Metering device for the inhalation of a pulverulent substance
JP2013515577A (ja) * 2009-12-23 2013-05-09 マップ ファーマシューティカルズ， インコーポレイテッド 強化排出装置設計
JP2017164554A (ja) * 2009-12-23 2017-09-21 マップ・ファーマシューティカルズ・インコーポレイテッド 強化排出装置設計
JP2015526226A (ja) * 2012-08-28 2015-09-10 カインド・コンシューマー・リミテッドＫｉｎｄ Ｃｏｎｓｕｍｅｒ Ｌｉｍｉｔｅｄ プルームに空気ジェットが衝突する呼吸作動式吸入器
JP2019513477A (ja) * 2016-04-15 2019-05-30 アプター フランス エスアーエス 吸気同期式の流体吐出装置
JP2019513478A (ja) * 2016-04-15 2019-05-30 アプター フランス エスアーエス 吸気同期式の流体吐出装置
JP2021526945A (ja) * 2018-06-04 2021-10-11 トゥルーデル メディカル インターナショナル 陽気圧治療装置、そのキット、並びに使用法及び組み立て法
JP7313439B2 (ja) 2018-06-04 2023-07-24 トゥルーデル メディカル インターナショナル 陽気圧治療装置、そのキット、並びに使用法及び組み立て法

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