JP5395100B2 - エアロゾル化薬剤の送出方法と装置 - Google Patents
エアロゾル化薬剤の送出方法と装置 Download PDFInfo
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- JP5395100B2 JP5395100B2 JP2011031934A JP2011031934A JP5395100B2 JP 5395100 B2 JP5395100 B2 JP 5395100B2 JP 2011031934 A JP2011031934 A JP 2011031934A JP 2011031934 A JP2011031934 A JP 2011031934A JP 5395100 B2 JP5395100 B2 JP 5395100B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
- A61M15/0088—Inhalation chambers with variable volume
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0095—Preventing manual activation in absence of inhalation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Description
Claims (9)
- エアロゾル流制御装置であって、
レセプタクル部、ならびに、使用者の口に挿入されるように形成された開放端、開放端から離れた実質的な閉鎖端、および開放端と閉鎖端との間を縦方向に延びる内壁を有する導管を含むハウジングと、
ハウジングのレセプタクル部内に配設され、エアロゾル化薬剤を導管内に分与する薬剤ディスペンサと、
内壁に隣接する導管の実質的な閉鎖端を貫通して形成された複数の空気入口と、
空気入口の下流かつ薬剤ディスペンサの下流の内壁に取り付けられた複数の動かない渦発生器とを備えており、
これによって導管の開放端に与えられる吸入の試みで、空気が空気入口を介して渦発生器の上を通って吸気され、それにより周方向に渦を巻く乱流境界層流が、導管の内壁に沿って作られ、薬剤の衝突および付着を減少させることを特徴とする、前記エアロゾル流制御装置。 - 薬剤ディスペンサが、薬剤を含有する加圧キャニスタを含み、ハウジングが、キャニスタの中空排出軸を受容するように形成されたアクチュエータ・ノズルアセンブリを含み、アクチュエータ・ノズルアセンブリは、薬剤を導管内に排出するために設けられたノズル排出オリフィスを有している請求項1に記載のエアロゾル流制御装置。
- 導管の開放端に吸入の試みが与えられると、空気が空気管の入口に流入して空気管の出口から流出するように、ノズル排出オリフィスと対向して配置された出口と、導管の外側の周囲空気と流体連通をする入口とを有するとともに、導管内に支持された空気管を更に備えており、この空気管は、空気管の出口から流出する空気が、方向付けられて、ノズル排出オリフィスを介してキャニスタから排出されるエアロゾル化薬剤の噴霧に衝突するように、配向されている請求項2に記載のエアロゾル流制御装置。
- エアロゾル流制御装置であって、
内壁と開放端とを持つ略管状の導管を含むハウジングと、
ハウジング内に配置され、エアロゾル化薬剤を導管内に分与する薬剤ディスペンサアセンブリと、
薬剤ディスペンサの下流で導管の内壁に取り付けられており、空気流が導管の開放端を介して形成されると、周方向に渦を巻く乱流境界層流を導管の内壁に沿って形成する複数の動かない渦発生器とを備える、前記エアロゾル流制御装置。 - 導管が、開放端から離れた端壁によって画定される実質的な閉鎖端を含み、端壁が、導管の外側の周囲空気と流体連通して、渦発生器の上流側の内壁に隣接する導管内に開口する複数の補助空気入口を含み、補助空気入口と渦発生器とが協働して、導管の内面に沿った乱流境界層流を形成する請求項4に記載のエアロゾル流制御装置。
- 薬剤ディスペンサアセンブリが、薬剤の加圧キャニスタと、アクチュエータと、キャニスタの中空出口軸を受容するように形成された孔を含むノズルアセンブリと、孔と流体連通して、エアロゾル化薬剤の噴霧を導管内に方向付けするように配置されたノズル排出オリフィスとを備える請求項5に記載のエアロゾル流制御装置。
- 渦発生器が、導管の内壁に取り付けられ、導管の縦軸によって画定される方向と角度をなして配向されたベーンを備えている請求項6に記載のエアロゾル流制御装置。
- 端壁が、導管の開放端から最も離れた端壁の部分を形成する端壁の頂端を持つ、略円錐形または半球形であり、ノズル排出オリフィスが、頂端に配置され、補助空気入口が、導管の端壁と内壁との間の接合点に隣接配置されている請求項7に記載のエアロゾル流制御装置。
- アクチュエータ・ノズルアセンブリが、孔と流体連通する第2のノズル排出オリフィスを含み、2つのノズル排出オリフィスが、エアロゾル化薬剤の分散と混合を促進するように、オリフィスから排出される噴霧が導管内で互いに衝突するように、互いに対して離間し、角度をなして配向されている請求項8に記載のエアロゾル流制御装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/954,352 US5954047A (en) | 1997-10-17 | 1997-10-17 | Methods and apparatus for delivering aerosolized medication |
US08/954,352 | 1997-10-17 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2000516721A Division JP2001520088A (ja) | 1997-10-17 | 1998-10-15 | エアロゾル化薬剤の送出方法と装置 |
Publications (2)
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JP2011098224A JP2011098224A (ja) | 2011-05-19 |
JP5395100B2 true JP5395100B2 (ja) | 2014-01-22 |
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JP2000516721A Pending JP2001520088A (ja) | 1997-10-17 | 1998-10-15 | エアロゾル化薬剤の送出方法と装置 |
JP2009092696A Withdrawn JP2009183734A (ja) | 1997-10-17 | 2009-04-07 | エアロゾル化薬剤の送出方法と装置 |
JP2010043745A Expired - Lifetime JP5114515B2 (ja) | 1997-10-17 | 2010-03-01 | エアロゾル化薬剤の送出方法と装置 |
JP2011031934A Expired - Lifetime JP5395100B2 (ja) | 1997-10-17 | 2011-02-17 | エアロゾル化薬剤の送出方法と装置 |
JP2011146003A Expired - Lifetime JP5352630B2 (ja) | 1997-10-17 | 2011-06-30 | エアロゾル流制御装置 |
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JP2000516721A Pending JP2001520088A (ja) | 1997-10-17 | 1998-10-15 | エアロゾル化薬剤の送出方法と装置 |
JP2009092696A Withdrawn JP2009183734A (ja) | 1997-10-17 | 2009-04-07 | エアロゾル化薬剤の送出方法と装置 |
JP2010043745A Expired - Lifetime JP5114515B2 (ja) | 1997-10-17 | 2010-03-01 | エアロゾル化薬剤の送出方法と装置 |
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JP2011146003A Expired - Lifetime JP5352630B2 (ja) | 1997-10-17 | 2011-06-30 | エアロゾル流制御装置 |
Country Status (16)
Country | Link |
---|---|
US (3) | US5954047A (ja) |
EP (3) | EP0911048B1 (ja) |
JP (5) | JP2001520088A (ja) |
KR (1) | KR20010031187A (ja) |
CN (1) | CN1285759A (ja) |
AT (2) | ATE311913T1 (ja) |
AU (1) | AU750459B2 (ja) |
CA (3) | CA2565964C (ja) |
DE (2) | DE69832679T2 (ja) |
DK (2) | DK1591137T3 (ja) |
ES (2) | ES2255134T3 (ja) |
MX (1) | MXPA00003766A (ja) |
NO (1) | NO983631L (ja) |
NZ (1) | NZ504021A (ja) |
TR (1) | TR200001033T2 (ja) |
WO (1) | WO1999020331A1 (ja) |
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1997
- 1997-10-17 NZ NZ504021A patent/NZ504021A/xx not_active Application Discontinuation
- 1997-10-17 US US08/954,352 patent/US5954047A/en not_active Expired - Lifetime
-
1998
- 1998-07-14 CA CA002565964A patent/CA2565964C/en not_active Expired - Lifetime
- 1998-07-14 CA CA002565088A patent/CA2565088C/en not_active Expired - Lifetime
- 1998-07-14 CA CA002243175A patent/CA2243175C/en not_active Expired - Lifetime
- 1998-07-31 DE DE69832679T patent/DE69832679T2/de not_active Expired - Lifetime
- 1998-07-31 EP EP98306113A patent/EP0911048B1/en not_active Expired - Lifetime
- 1998-07-31 DK DK05076801.9T patent/DK1591137T3/da active
- 1998-07-31 AT AT98306113T patent/ATE311913T1/de active
- 1998-07-31 AT AT05076801T patent/ATE463271T1/de active
- 1998-07-31 EP EP05076801A patent/EP1591137B1/en not_active Expired - Lifetime
- 1998-07-31 EP EP05076802.7A patent/EP1627655B1/en not_active Expired - Lifetime
- 1998-07-31 ES ES98306113T patent/ES2255134T3/es not_active Expired - Lifetime
- 1998-07-31 DE DE69841603T patent/DE69841603D1/de not_active Expired - Lifetime
- 1998-07-31 DK DK98306113T patent/DK0911048T3/da active
- 1998-07-31 ES ES05076801T patent/ES2348495T3/es not_active Expired - Lifetime
- 1998-08-07 NO NO983631A patent/NO983631L/no not_active Application Discontinuation
- 1998-10-15 JP JP2000516721A patent/JP2001520088A/ja active Pending
- 1998-10-15 CN CN98811903A patent/CN1285759A/zh active Pending
- 1998-10-15 AU AU10847/99A patent/AU750459B2/en not_active Expired
- 1998-10-15 WO PCT/US1998/021667 patent/WO1999020331A1/en not_active Application Discontinuation
- 1998-10-15 MX MXPA00003766A patent/MXPA00003766A/es active IP Right Grant
- 1998-10-15 TR TR2000/01033T patent/TR200001033T2/xx unknown
- 1998-10-15 KR KR1020007004125A patent/KR20010031187A/ko not_active Application Discontinuation
-
1999
- 1999-06-07 US US09/326,531 patent/US6095141A/en not_active Expired - Lifetime
- 1999-06-07 US US09/326,538 patent/US6026808A/en not_active Expired - Lifetime
-
2009
- 2009-04-07 JP JP2009092696A patent/JP2009183734A/ja not_active Withdrawn
-
2010
- 2010-03-01 JP JP2010043745A patent/JP5114515B2/ja not_active Expired - Lifetime
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2011
- 2011-02-17 JP JP2011031934A patent/JP5395100B2/ja not_active Expired - Lifetime
- 2011-06-30 JP JP2011146003A patent/JP5352630B2/ja not_active Expired - Lifetime
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