JP2000503586A - 薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置 - Google Patents

薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置

Info

Publication number
JP2000503586A
JP2000503586A JP11511309A JP51130999A JP2000503586A JP 2000503586 A JP2000503586 A JP 2000503586A JP 11511309 A JP11511309 A JP 11511309A JP 51130999 A JP51130999 A JP 51130999A JP 2000503586 A JP2000503586 A JP 2000503586A
Authority
JP
Japan
Prior art keywords
electrode
applicator
needle
electroporation
needles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11511309A
Other languages
English (en)
Japanese (ja)
Inventor
ホフマン，ガンター，エイ．
デブ，スケンデュ，ビー．
ダイマー，スティーブン，シー．
レヴァター，ジェフリー，アイ．
ナンダ，ガーヴィンダー，エス．
Original Assignee
ジェネトロニクス，インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェネトロニクス，インコーポレーテッド filed Critical ジェネトロニクス，インコーポレーテッド
Publication of JP2000503586A publication Critical patent/JP2000503586A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502—Skin piercing electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrotherapy Devices (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP11511309A 1997-08-01 1998-07-31 薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置 Pending JP2000503586A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/905,240 1997-08-01
US08/905,240 US6055453A (en) 1997-08-01 1997-08-01 Apparatus for addressing needle array electrodes for electroporation therapy
PCT/US1998/016042 WO1999006101A1 (en) 1997-08-01 1998-07-31 Method and apparatus for using electroporation mediated delivery of drugs and genes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2002057679A Division JP4180285B2 (ja) 1997-08-01 2002-03-04 薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置

Publications (1)

Publication Number Publication Date
JP2000503586A true JP2000503586A (ja) 2000-03-28

Family

ID=25420478

Family Applications (2)

Application Number Title Priority Date Filing Date
JP11511309A Pending JP2000503586A (ja) 1997-08-01 1998-07-31 薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置
JP2002057679A Expired - Lifetime JP4180285B2 (ja) 1997-08-01 2002-03-04 薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2002057679A Expired - Lifetime JP4180285B2 (ja) 1997-08-01 2002-03-04 薬剤及び遺伝子の分配に供する電気穿孔法を使用した方法及び装置

Country Status (13)

Country Link
US (5) US6055453A (https=)
EP (1) EP0999867B1 (https=)
JP (2) JP2000503586A (https=)
KR (1) KR100756252B1 (https=)
CN (2) CN1768873B (https=)
AT (1) ATE480294T1 (https=)
AU (1) AU734343B2 (https=)
BR (1) BR9806069A (https=)
CA (1) CA2268026C (https=)
DE (1) DE69841888D1 (https=)
RU (1) RU2195332C2 (https=)
TW (1) TW396043B (https=)
WO (1) WO1999006101A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002505171A (ja) * 1998-03-06 2002-02-19 アルテア テクノロジーズ， インコーポレイテッド 微小穿孔された組織を通して電気穿孔するための装置
JP2003501134A (ja) * 1999-06-04 2003-01-14 サイムド ライフ システムズ， インコーポレイテッド 電極の急速展開
JP2007507247A (ja) * 2003-09-29 2007-03-29 エミシジョン リミテッド 外科的切除装置
JP2008503292A (ja) * 2004-06-24 2008-02-07 スフェルゲン 電気力を使用して分子を細胞に移動させるデバイス
JP2009528131A (ja) * 2006-03-03 2009-08-06 ジェネトロニクス，インコーポレイティド 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置
JP2017170161A (ja) * 2011-06-28 2017-09-28 イノビオ ファーマシューティカルズ，インコーポレイティド 低侵襲表皮電気穿孔装置
JP2020528325A (ja) * 2017-07-28 2020-09-24 スカンディナヴィアン キーモテック アーベー 電気パルスを哺乳動物の望ましい組織へ送達するために使用する電極装置および針電極

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JP2020028759A (ja) * 2011-06-28 2020-02-27 イノビオ ファーマシューティカルズ，インコーポレイティド 低侵襲表皮電気穿孔装置
US11291836B2 (en) 2011-06-28 2022-04-05 Inovio Pharmaceuticals, Inc. Minimally invasive dermal electroporation device
US12251561B2 (en) 2011-06-28 2025-03-18 Inovio Pharmaceuticals, Inc. Minimally invasive dermal electroporation device
JP2019058671A (ja) * 2011-06-28 2019-04-18 イノビオ ファーマシューティカルズ，インコーポレイティド 低侵襲表皮電気穿孔装置
JP2020528325A (ja) * 2017-07-28 2020-09-24 スカンディナヴィアン キーモテック アーベー 電気パルスを哺乳動物の望ましい組織へ送達するために使用する電極装置および針電極
JP7093832B2 (ja) 2017-07-28 2022-06-30 スカンディナヴィアン キーモテック アーベー 電気パルスを哺乳動物の望ましい組織へ送達するために使用する電極装置および針電極

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CA2268026A1 (en) 1999-02-11
CN1768873A (zh) 2006-05-10
KR20000068678A (ko) 2000-11-25
JP2002291910A (ja) 2002-10-08
RU2195332C2 (ru) 2002-12-27
ATE480294T1 (de) 2010-09-15
US6014584A (en) 2000-01-11
AU8682398A (en) 1999-02-22
TW396043B (en) 2000-07-01
DE69841888D1 (de) 2010-10-21
CN1248923A (zh) 2000-03-29
JP4180285B2 (ja) 2008-11-12
CN1217717C (zh) 2005-09-07
US6055453A (en) 2000-04-25
KR100756252B1 (ko) 2007-09-07
BR9806069A (pt) 2000-01-25
CA2268026C (en) 2003-07-29
EP0999867B1 (en) 2010-09-08
US6181964B1 (en) 2001-01-30
AU734343B2 (en) 2001-06-14
US6233482B1 (en) 2001-05-15
CN1768873B (zh) 2011-04-13
US6068650A (en) 2000-05-30
WO1999006101A1 (en) 1999-02-11
HK1027049A1 (en) 2001-01-05
EP0999867A4 (en) 2008-03-26

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