IT1205418B - Cdna di manganese superossido dismutasi umana sua espressione in batteri e metodo per il recupero di manganese superossido dismutasi umana - Google Patents

Cdna di manganese superossido dismutasi umana sua espressione in batteri e metodo per il recupero di manganese superossido dismutasi umana

Info

Publication number
IT1205418B
IT1205418B IT67865/86A IT6786586A IT1205418B IT 1205418 B IT1205418 B IT 1205418B IT 67865/86 A IT67865/86 A IT 67865/86A IT 6786586 A IT6786586 A IT 6786586A IT 1205418 B IT1205418 B IT 1205418B
Authority
IT
Italy
Prior art keywords
dismutasi
human
manganese superoxide
cdna
bacteria
Prior art date
Application number
IT67865/86A
Other languages
English (en)
Italian (it)
Other versions
IT8667865A0 (it
Inventor
Jacob R Hartman
Yaffa Beck
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Publication of IT8667865A0 publication Critical patent/IT8667865A0/it
Application granted granted Critical
Publication of IT1205418B publication Critical patent/IT1205418B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0089Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT67865/86A 1985-11-22 1986-11-21 Cdna di manganese superossido dismutasi umana sua espressione in batteri e metodo per il recupero di manganese superossido dismutasi umana IT1205418B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80109085A 1985-11-22 1985-11-22
US90705186A 1986-09-12 1986-09-12

Publications (2)

Publication Number Publication Date
IT8667865A0 IT8667865A0 (it) 1986-11-21
IT1205418B true IT1205418B (it) 1989-03-15

Family

ID=27122291

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67865/86A IT1205418B (it) 1985-11-22 1986-11-21 Cdna di manganese superossido dismutasi umana sua espressione in batteri e metodo per il recupero di manganese superossido dismutasi umana

Country Status (21)

Country Link
JP (2) JP2609449B2 (enrdf_load_stackoverflow)
AT (1) AT400443B (enrdf_load_stackoverflow)
AU (1) AU607897B2 (enrdf_load_stackoverflow)
BE (1) BE905796A (enrdf_load_stackoverflow)
CA (1) CA1341362C (enrdf_load_stackoverflow)
CH (1) CH676990A5 (enrdf_load_stackoverflow)
DE (1) DE3639725C2 (enrdf_load_stackoverflow)
DK (1) DK534686A (enrdf_load_stackoverflow)
ES (1) ES2003518A6 (enrdf_load_stackoverflow)
FI (1) FI90353C (enrdf_load_stackoverflow)
FR (1) FR2590591B1 (enrdf_load_stackoverflow)
GB (1) GB2183658B (enrdf_load_stackoverflow)
GR (1) GR862713B (enrdf_load_stackoverflow)
HK (1) HK75195A (enrdf_load_stackoverflow)
IE (1) IE59498B1 (enrdf_load_stackoverflow)
IL (2) IL80702A0 (enrdf_load_stackoverflow)
IT (1) IT1205418B (enrdf_load_stackoverflow)
LU (1) LU86676A1 (enrdf_load_stackoverflow)
NL (1) NL8602960A (enrdf_load_stackoverflow)
PT (1) PT83792B (enrdf_load_stackoverflow)
SE (1) SE8604884L (enrdf_load_stackoverflow)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610520B1 (en) * 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS62215532A (ja) * 1986-03-18 1987-09-22 Ube Ind Ltd 抗炎症剤
JPH0643341B2 (ja) * 1986-03-27 1994-06-08 宇部興産株式会社 臓器機能改善剤
JPH0643340B2 (ja) * 1986-09-03 1994-06-08 宇部興産株式会社 虚血性心疾患治療薬
JPS6377822A (ja) * 1986-09-18 1988-04-08 Ube Ind Ltd 臓器機能改善剤
US6326003B1 (en) 1986-10-14 2001-12-04 Chiron Corporation Manganese superoxide dismutase cloning and expression in microorganisms
ATE132902T1 (de) * 1987-03-14 1996-01-15 Boehringer Ingelheim Int Humane mangan-superoxiddismutase (hmn-sod)
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
EP0284105B1 (en) * 1987-03-27 1995-11-15 Bio-Technology General Corporation Human manganese superoxide dismutase and methods of treatment
JPH01233228A (ja) * 1988-03-11 1989-09-19 Toyo Jozo Co Ltd 悪性腫瘍細胞転移防止剤
US5772996A (en) * 1990-08-03 1998-06-30 Public Health Laboratory Service Board Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
DE4038563A1 (de) * 1990-12-04 1992-06-11 Gruenenthal Gmbh Verwendung von superoxiddismutasen zur prophylaxe und/oder behandlung von organversagen bei risikopatienten mit polytrauma
DE59310242D1 (de) * 1992-09-09 2002-01-17 Bio Technology General Corp Verwendung von Mangan-Superoxiddismutase (Mn-SOD) zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen in niedriger Dosierung
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
BG49718A3 (bg) * 1983-07-15 1992-01-15 Bio- Technology General Corp Метод за получаване на полипептид със супероксиддисмутазна активност
DE3485284D1 (de) * 1983-10-03 1992-01-02 Chiron Corp Klonieren von superoxid-dismutase und expression in mikroorganismen.

Also Published As

Publication number Publication date
GB2183658A (en) 1987-06-10
DE3639725C2 (de) 1998-02-19
CH676990A5 (enrdf_load_stackoverflow) 1991-03-28
SE8604884L (sv) 1987-05-23
FI90353B (fi) 1993-10-15
FR2590591B1 (fr) 1989-12-01
DK534686A (da) 1987-05-23
FI864756A7 (fi) 1987-05-23
JPH08289792A (ja) 1996-11-05
NL8602960A (nl) 1987-06-16
AT400443B (de) 1995-12-27
FI864756A0 (fi) 1986-11-21
PT83792A (en) 1986-12-01
IL80702A0 (en) 1987-02-27
LU86676A1 (fr) 1987-05-04
IT8667865A0 (it) 1986-11-21
AU607897B2 (en) 1991-03-21
HK75195A (en) 1995-05-26
ATA308986A (de) 1995-05-15
GB2183658B (en) 1990-04-25
FI90353C (fi) 1994-01-25
BE905796A (fr) 1987-03-16
JP2967557B2 (ja) 1999-10-25
IL106449A0 (en) 1993-11-15
IL106449A (en) 1997-02-18
IE862851L (en) 1987-05-22
GR862713B (en) 1987-03-24
DE3639725A1 (de) 1987-07-23
AU6497586A (en) 1987-05-28
PT83792B (pt) 1989-01-17
JPS62289187A (ja) 1987-12-16
FR2590591A1 (fr) 1987-05-29
JP2609449B2 (ja) 1997-05-14
DK534686D0 (da) 1986-11-07
GB8627294D0 (en) 1986-12-17
CA1341362C (en) 2002-05-28
SE8604884D0 (sv) 1986-11-14
IE59498B1 (en) 1994-03-09
ES2003518A6 (es) 1988-11-01

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971031