BE905796A - Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine. - Google Patents
Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine.Info
- Publication number
- BE905796A BE905796A BE0/217445A BE217445A BE905796A BE 905796 A BE905796 A BE 905796A BE 0/217445 A BE0/217445 A BE 0/217445A BE 217445 A BE217445 A BE 217445A BE 905796 A BE905796 A BE 905796A
- Authority
- BE
- Belgium
- Prior art keywords
- superoxide dismutase
- manganese superoxide
- human manganese
- bacteria
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Molécule d'ADN à double brin qui comprend de l'ADN encodant de la superoxyde dismutase de manganèse humaine, ces molécules pouvant etre introduites dans des cellules procaryotiques, par exemple bactériennes, ou eucaryotiques, par exemple des levures ou des cellules de mammifères, les cellules résultantes étant cultivées sous des conditions appropriées de manière à produire de la superoxyde dismutase de manganèse humaine ou des analogues de celle-ci qui peuvent ensuite etre récupérés.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80109085A | 1985-11-22 | 1985-11-22 | |
US90705186A | 1986-09-12 | 1986-09-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE905796A true BE905796A (fr) | 1987-03-16 |
Family
ID=27122291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/217445A BE905796A (fr) | 1985-11-22 | 1986-11-20 | Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine. |
Country Status (21)
Country | Link |
---|---|
JP (2) | JP2609449B2 (fr) |
AT (1) | AT400443B (fr) |
AU (1) | AU607897B2 (fr) |
BE (1) | BE905796A (fr) |
CA (1) | CA1341362C (fr) |
CH (1) | CH676990A5 (fr) |
DE (1) | DE3639725C2 (fr) |
DK (1) | DK534686A (fr) |
ES (1) | ES2003518A6 (fr) |
FI (1) | FI90353C (fr) |
FR (1) | FR2590591B1 (fr) |
GB (1) | GB2183658B (fr) |
GR (1) | GR862713B (fr) |
HK (1) | HK75195A (fr) |
IE (1) | IE59498B1 (fr) |
IL (2) | IL106449A (fr) |
IT (1) | IT1205418B (fr) |
LU (1) | LU86676A1 (fr) |
NL (1) | NL8602960A (fr) |
PT (1) | PT83792B (fr) |
SE (1) | SE8604884L (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0284105B1 (fr) * | 1987-03-27 | 1995-11-15 | Bio-Technology General Corporation | Manganèse superoxyde dismutase humaine et méthodes de traitement |
EP0282899B1 (fr) * | 1987-03-14 | 1996-01-10 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | La manganèse-superoxyde-dismutase humaine (hMn-SOD) |
US5540911A (en) * | 1985-11-22 | 1996-07-30 | Bio-Technology General Corp. | Methods of use of human manganese superoxide dismutase |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62215532A (ja) * | 1986-03-18 | 1987-09-22 | Ube Ind Ltd | 抗炎症剤 |
JPH0643341B2 (ja) * | 1986-03-27 | 1994-06-08 | 宇部興産株式会社 | 臓器機能改善剤 |
JPH0643340B2 (ja) * | 1986-09-03 | 1994-06-08 | 宇部興産株式会社 | 虚血性心疾患治療薬 |
JPS6377822A (ja) * | 1986-09-18 | 1988-04-08 | Ube Ind Ltd | 臓器機能改善剤 |
US6326003B1 (en) | 1986-10-14 | 2001-12-04 | Chiron Corporation | Manganese superoxide dismutase cloning and expression in microorganisms |
US5260204A (en) * | 1987-03-14 | 1993-11-09 | Boehringer Ingelheim International Gmbh | Human manganese superoxide dismutase (hMn-SOD) |
JPH01233228A (ja) * | 1988-03-11 | 1989-09-19 | Toyo Jozo Co Ltd | 悪性腫瘍細胞転移防止剤 |
US5772996A (en) * | 1990-08-03 | 1998-06-30 | Public Health Laboratory Service Board | Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax |
DE4038563A1 (de) * | 1990-12-04 | 1992-06-11 | Gruenenthal Gmbh | Verwendung von superoxiddismutasen zur prophylaxe und/oder behandlung von organversagen bei risikopatienten mit polytrauma |
EP0587055B1 (fr) * | 1992-09-09 | 2001-12-05 | Bio-Technology General Corporation | Utilisation de manganèse superoxyde dismutase (Mn-SOD) en bas dosage pour la production de médicaments pour le traitement de maladies |
DE4239877C1 (de) * | 1992-11-27 | 1994-03-17 | Boehringer Ingelheim Int | Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56102787A (en) * | 1980-01-18 | 1981-08-17 | Mamoru Sugiura | Preparation of human placenta superoxide dismutase |
BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio- Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
EP0138111B1 (fr) * | 1983-10-03 | 1991-11-21 | Chiron Corporation | Clonage de la dismutase du peroxyde et expression dans des micro-organismes |
-
1986
- 1986-10-29 IE IE285186A patent/IE59498B1/en not_active IP Right Cessation
- 1986-11-07 DK DK534686A patent/DK534686A/da not_active Application Discontinuation
- 1986-11-10 AU AU64975/86A patent/AU607897B2/en not_active Ceased
- 1986-11-13 GR GR862713A patent/GR862713B/el unknown
- 1986-11-14 SE SE8604884A patent/SE8604884L/xx not_active Application Discontinuation
- 1986-11-14 GB GB8627294A patent/GB2183658B/en not_active Expired - Fee Related
- 1986-11-18 ES ES8603083A patent/ES2003518A6/es not_active Expired
- 1986-11-19 AT AT0308986A patent/AT400443B/de not_active IP Right Cessation
- 1986-11-20 IL IL10644986A patent/IL106449A/xx active IP Right Grant
- 1986-11-20 IL IL80702A patent/IL80702A0/xx unknown
- 1986-11-20 LU LU86676A patent/LU86676A1/fr unknown
- 1986-11-20 BE BE0/217445A patent/BE905796A/fr not_active IP Right Cessation
- 1986-11-21 NL NL8602960A patent/NL8602960A/nl active Search and Examination
- 1986-11-21 JP JP61278528A patent/JP2609449B2/ja not_active Expired - Lifetime
- 1986-11-21 CA CA000523536A patent/CA1341362C/fr not_active Expired - Lifetime
- 1986-11-21 DE DE3639725A patent/DE3639725C2/de not_active Expired - Fee Related
- 1986-11-21 PT PT83792A patent/PT83792B/pt not_active IP Right Cessation
- 1986-11-21 IT IT67865/86A patent/IT1205418B/it active
- 1986-11-21 FI FI864756A patent/FI90353C/fi not_active IP Right Cessation
- 1986-11-21 FR FR868616238A patent/FR2590591B1/fr not_active Expired
- 1986-11-21 CH CH4680/86A patent/CH676990A5/de not_active IP Right Cessation
-
1995
- 1995-05-18 HK HK75195A patent/HK75195A/xx not_active IP Right Cessation
-
1996
- 1996-01-22 JP JP8008627A patent/JP2967557B2/ja not_active Expired - Fee Related
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5540911A (en) * | 1985-11-22 | 1996-07-30 | Bio-Technology General Corp. | Methods of use of human manganese superoxide dismutase |
US6361772B1 (en) | 1985-11-22 | 2002-03-26 | Bio-Technology General Corp. | Human manganese superoxide dismutase DNA, its expression and method of recovering human manganese superoxide dismutase |
US6610520B1 (en) | 1985-11-22 | 2003-08-26 | Bio-Technology General Corp. | Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby |
EP0282899B1 (fr) * | 1987-03-14 | 1996-01-10 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | La manganèse-superoxyde-dismutase humaine (hMn-SOD) |
EP0284105B1 (fr) * | 1987-03-27 | 1995-11-15 | Bio-Technology General Corporation | Manganèse superoxyde dismutase humaine et méthodes de traitement |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: *BIO-TECHNOLOGY GENERAL CORP. Effective date: 20021130 |