YU61799A - Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima - Google Patents
Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmimaInfo
- Publication number
- YU61799A YU61799A YU61799A YU61799A YU61799A YU 61799 A YU61799 A YU 61799A YU 61799 A YU61799 A YU 61799A YU 61799 A YU61799 A YU 61799A YU 61799 A YU61799 A YU 61799A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- pan
- pantothenic acid
- microorganisms
- production
- fermentativen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Pronalazak se odnosi na postupak za proizvodnju D-pantotenske kiseline fermentacijom mikroorganizama, u kojima se bar panD-gen pojačava (prekomerno izražava), u datom slučaju u kombinaciji sa panB- i/ili pan C-genom, i obogaćivanjem sadržaja pantotenske kiseline u sredini ili u ćelijama mikroorganizama.[The invention refers to the production of the D-pantothenic acid by the fermentation of microorganisms, wherein the bar of D-gene is amplified (expressed overmeasure) in the given case with the combination with pan B- and/or pan C - gene, and enriching content of pantothenic acid in the environment or in microorganism cells.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19855313A DE19855313A1 (de) | 1998-12-01 | 1998-12-01 | Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen |
Publications (1)
Publication Number | Publication Date |
---|---|
YU61799A true YU61799A (sh) | 2003-02-28 |
Family
ID=7889569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU61799A YU61799A (sh) | 1998-12-01 | 1999-11-26 | Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima |
Country Status (14)
Country | Link |
---|---|
US (1) | US6184007B1 (sh) |
EP (1) | EP1006192B1 (sh) |
JP (1) | JP2000228990A (sh) |
KR (1) | KR20000047829A (sh) |
CN (1) | CN1256314A (sh) |
AT (1) | ATE442443T1 (sh) |
BR (1) | BR9905776A (sh) |
DE (2) | DE19855313A1 (sh) |
HU (1) | HUP9904447A2 (sh) |
ID (1) | ID24149A (sh) |
IL (1) | IL133214A0 (sh) |
SK (1) | SK163399A3 (sh) |
YU (1) | YU61799A (sh) |
ZA (1) | ZA997406B (sh) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
DE19855312A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
HU230509B1 (hu) * | 1999-09-21 | 2016-09-28 | Basf Aktiengesellschaft | Eljárások és mikroorganizmusok panto-vegyületek előállítására |
US8232081B2 (en) | 1999-09-21 | 2012-07-31 | Basf Se | Methods and microorganisms for production of panto-compounds |
DE10030702A1 (de) | 2000-06-23 | 2002-01-03 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
AU2001293740A1 (en) * | 2000-09-02 | 2002-03-13 | Degussa A.G. | Nucleotide sequence coding for the sigc gene of corynebacterium glutamicum |
DE10136986A1 (de) * | 2000-09-03 | 2002-03-21 | Degussa | Für Gene cysD, cysN, cysK, cysE und cysH kodierende Nukleotidsequenzen |
DE10046623A1 (de) * | 2000-09-20 | 2002-03-28 | Degussa | Neue für das dps-Gen kodierende Nukleotidsequenzen |
BR0206586A (pt) * | 2001-01-19 | 2006-01-24 | Basf Ag | Processo para a produção de pantotenato aumentada, produto, composição, e, microorganismo recombinante para a produção de pantotenato aumentada |
AU2002308290A1 (en) * | 2001-02-21 | 2002-09-04 | Basf Aktiengesellschaft | Method for the production of D-pantothenic acid and/or salts thereof as adjunct for animal feedstuffs |
DE10108223A1 (de) * | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
DE10108225A1 (de) * | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
JP2004523237A (ja) | 2001-02-21 | 2004-08-05 | ビーエーエスエフ アクチェンゲゼルシャフト | 動物飼料添加剤としてのd−パントテン酸および/またはその塩の製造方法 |
DE10116519A1 (de) * | 2001-04-03 | 2002-10-17 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salze |
EP1247868A3 (de) * | 2001-04-03 | 2002-10-30 | Degussa AG | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
WO2003004672A1 (en) * | 2001-07-03 | 2003-01-16 | Degussa Ag | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
WO2003004673A1 (en) * | 2001-07-03 | 2003-01-16 | Degussa Ag | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
DE10132178A1 (de) * | 2001-07-03 | 2003-01-23 | Degussa | Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen |
US7338792B2 (en) * | 2001-07-07 | 2008-03-04 | Degussa Ag | Process for the preparation of D-pantothenic acid and/or salts thereof |
DE10147960A1 (de) * | 2001-09-28 | 2003-04-10 | Degussa | Verfahren zur fermentativen Herstellung von D-Panthothensäure und/oder deren Salzen |
CA2491145A1 (en) * | 2002-07-03 | 2004-01-15 | Basf Aktiengesellschaft | Microorganisms and processes for enhanced production of pantothenate |
US20070180585A1 (en) * | 2004-03-17 | 2007-08-02 | Bala Rathinasabapathi | Increased stress tolerance and enhanced yield in plants |
DE102005048818A1 (de) | 2005-10-10 | 2007-04-12 | Degussa Ag | Mikrobiologische Herstellung von 3-Hydroxypropionsäure |
US9238687B2 (en) | 2006-04-13 | 2016-01-19 | Chugai Seiyaku Kabushiki Kaisha | Method for recombinant production of a desired polypeptide using a mammalian cell co-expressing a taurine transporter polypeptide |
US20100233759A1 (en) | 2007-03-15 | 2010-09-16 | Chugai Seiyaku Kabushiki Kaisha | Method for production of polypeptide |
DE102007015583A1 (de) | 2007-03-29 | 2008-10-02 | Albert-Ludwigs-Universität Freiburg | Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung |
DK2186905T3 (en) | 2007-08-07 | 2016-09-19 | Chugai Pharmaceutical Co Ltd | Method of Preparation of Heterogeneous Protein |
RU2486245C2 (ru) * | 2007-10-15 | 2013-06-27 | Чугаи Сейяку Кабусики Кайся | Способ получения клетки, способной продуцировать гетеропротеины с высоким выходом |
AU2008314973C1 (en) * | 2007-10-24 | 2014-05-08 | Chugai Seiyaku Kabushiki Kaisha | A cell for use in production of heteroproteins and production method using the same |
US8741601B2 (en) | 2009-04-22 | 2014-06-03 | Chugai Seiyaku Kabushiki Kaisha | Method for producing a cell capable of high-yield production of heteroproteins |
CN107354142A (zh) * | 2017-09-14 | 2017-11-17 | 精晶药业股份有限公司 | 一种L‑天门冬氨酸‑α‑脱羧酶酶液处理方法 |
CN109593748B (zh) * | 2017-10-01 | 2022-03-04 | 宁波酶赛生物工程有限公司 | 工程化脱羧酶多肽及其在制备β-丙氨酸中的应用 |
CN113122486B (zh) * | 2019-12-31 | 2023-06-13 | 江南大学 | 一种丙二酸的全生物合成的方法 |
KR102389327B1 (ko) * | 2020-07-01 | 2022-04-20 | 씨제이제일제당 (주) | 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도 |
KR102589135B1 (ko) * | 2021-05-10 | 2023-10-12 | 씨제이제일제당 (주) | 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도 |
CN113789307B (zh) * | 2021-09-10 | 2023-08-18 | 浙江工业大学 | 一种泛酸合成酶突变体、编码基因、载体及应用 |
KR20240105656A (ko) * | 2022-12-28 | 2024-07-08 | 씨제이제일제당 (주) | 음이온 수송 단백질의 활성이 강화된 미생물 및 이의 용도 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0493060A3 (en) * | 1990-12-25 | 1993-04-14 | Takeda Chemical Industries, Ltd. | Production method of d-pantothenic acid and plasmids and microorganisms thereof |
JP3710497B2 (ja) * | 1992-09-25 | 2005-10-26 | ビーエーエスエフ アクチェンゲゼルシャフト | D−パント酸、d−パントテン酸およびそれらの塩の製造法 |
ATE264392T1 (de) | 1995-09-13 | 2004-04-15 | Basf Ag | Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salze |
DE19846499A1 (de) * | 1998-10-09 | 2000-04-20 | Degussa | Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen |
DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
KR20070087035A (ko) * | 1999-06-25 | 2007-08-27 | 바스프 악티엔게젤샤프트 | 대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰유전자 |
EP1083225A1 (de) * | 1999-09-09 | 2001-03-14 | Degussa-Hüls Aktiengesellschaft | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
-
1998
- 1998-12-01 DE DE19855313A patent/DE19855313A1/de not_active Ceased
-
1999
- 1999-05-26 US US09/318,793 patent/US6184007B1/en not_active Expired - Fee Related
- 1999-11-13 AT AT99122650T patent/ATE442443T1/de not_active IP Right Cessation
- 1999-11-13 EP EP99122650A patent/EP1006192B1/de not_active Expired - Lifetime
- 1999-11-13 DE DE59915077T patent/DE59915077D1/de not_active Expired - Fee Related
- 1999-11-26 YU YU61799A patent/YU61799A/sh unknown
- 1999-11-29 ID IDP991098A patent/ID24149A/id unknown
- 1999-11-30 HU HU9904447A patent/HUP9904447A2/hu unknown
- 1999-11-30 ZA ZA9907406A patent/ZA997406B/xx unknown
- 1999-11-30 SK SK1633-99A patent/SK163399A3/sk unknown
- 1999-11-30 IL IL13321499A patent/IL133214A0/xx unknown
- 1999-11-30 JP JP11340840A patent/JP2000228990A/ja not_active Ceased
- 1999-12-01 KR KR1019990054167A patent/KR20000047829A/ko not_active Application Discontinuation
- 1999-12-01 BR BR9905776-0A patent/BR9905776A/pt not_active Application Discontinuation
- 1999-12-01 CN CN99120980A patent/CN1256314A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA997406B (en) | 2000-06-08 |
US6184007B1 (en) | 2001-02-06 |
EP1006192A3 (de) | 2003-09-17 |
HUP9904447A2 (hu) | 2000-11-28 |
BR9905776A (pt) | 2001-04-24 |
EP1006192A2 (de) | 2000-06-07 |
CN1256314A (zh) | 2000-06-14 |
ATE442443T1 (de) | 2009-09-15 |
DE59915077D1 (de) | 2009-10-22 |
JP2000228990A (ja) | 2000-08-22 |
DE19855313A1 (de) | 2000-06-08 |
KR20000047829A (ko) | 2000-07-25 |
EP1006192B1 (de) | 2009-09-09 |
SK163399A3 (en) | 2000-07-11 |
HU9904447D0 (en) | 2000-01-28 |
ID24149A (id) | 2000-07-13 |
IL133214A0 (en) | 2001-03-19 |
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