YU61799A - Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima - Google Patents

Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima

Info

Publication number
YU61799A
YU61799A YU61799A YU61799A YU61799A YU 61799 A YU61799 A YU 61799A YU 61799 A YU61799 A YU 61799A YU 61799 A YU61799 A YU 61799A YU 61799 A YU61799 A YU 61799A
Authority
YU
Yugoslavia
Prior art keywords
pan
pantothenic acid
microorganisms
production
fermentativen
Prior art date
Application number
YU61799A
Other languages
English (en)
Inventor
Nicole Dusch
Jorn Kalinowski
Alfred Puhler
Original Assignee
Degussa-Huls Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa-Huls Aktiengesellschaft filed Critical Degussa-Huls Aktiengesellschaft
Publication of YU61799A publication Critical patent/YU61799A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Pronalazak se odnosi na postupak za proizvodnju D-pantotenske kiseline fermentacijom mikroorganizama, u kojima se bar panD-gen pojačava (prekomerno izražava), u datom slučaju u kombinaciji sa panB- i/ili pan C-genom, i obogaćivanjem sadržaja pantotenske kiseline u sredini ili u ćelijama mikroorganizama.[The invention refers to the production of the D-pantothenic acid by the fermentation of microorganisms, wherein the bar of D-gene is amplified (expressed overmeasure) in the given case with the combination with pan B- and/or pan C - gene, and enriching content of pantothenic acid in the environment or in microorganism cells.
YU61799A 1998-12-01 1999-11-26 Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima YU61799A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19855313A DE19855313A1 (de) 1998-12-01 1998-12-01 Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen

Publications (1)

Publication Number Publication Date
YU61799A true YU61799A (sh) 2003-02-28

Family

ID=7889569

Family Applications (1)

Application Number Title Priority Date Filing Date
YU61799A YU61799A (sh) 1998-12-01 1999-11-26 Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima

Country Status (14)

Country Link
US (1) US6184007B1 (sh)
EP (1) EP1006192B1 (sh)
JP (1) JP2000228990A (sh)
KR (1) KR20000047829A (sh)
CN (1) CN1256314A (sh)
AT (1) ATE442443T1 (sh)
BR (1) BR9905776A (sh)
DE (2) DE19855313A1 (sh)
HU (1) HUP9904447A2 (sh)
ID (1) ID24149A (sh)
IL (1) IL133214A0 (sh)
SK (1) SK163399A3 (sh)
YU (1) YU61799A (sh)
ZA (1) ZA997406B (sh)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19855314A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE19855312A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien
HU230509B1 (hu) * 1999-09-21 2016-09-28 Basf Aktiengesellschaft Eljárások és mikroorganizmusok panto-vegyületek előállítására
US8232081B2 (en) 1999-09-21 2012-07-31 Basf Se Methods and microorganisms for production of panto-compounds
DE10030702A1 (de) 2000-06-23 2002-01-03 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien
AU2001293740A1 (en) * 2000-09-02 2002-03-13 Degussa A.G. Nucleotide sequence coding for the sigc gene of corynebacterium glutamicum
DE10136986A1 (de) * 2000-09-03 2002-03-21 Degussa Für Gene cysD, cysN, cysK, cysE und cysH kodierende Nukleotidsequenzen
DE10046623A1 (de) * 2000-09-20 2002-03-28 Degussa Neue für das dps-Gen kodierende Nukleotidsequenzen
BR0206586A (pt) * 2001-01-19 2006-01-24 Basf Ag Processo para a produção de pantotenato aumentada, produto, composição, e, microorganismo recombinante para a produção de pantotenato aumentada
AU2002308290A1 (en) * 2001-02-21 2002-09-04 Basf Aktiengesellschaft Method for the production of D-pantothenic acid and/or salts thereof as adjunct for animal feedstuffs
DE10108223A1 (de) * 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
DE10108225A1 (de) * 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
JP2004523237A (ja) 2001-02-21 2004-08-05 ビーエーエスエフ アクチェンゲゼルシャフト 動物飼料添加剤としてのｄ−パントテン酸および／またはその塩の製造方法
DE10116519A1 (de) * 2001-04-03 2002-10-17 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salze
EP1247868A3 (de) * 2001-04-03 2002-10-30 Degussa AG Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen
WO2003004672A1 (en) * 2001-07-03 2003-01-16 Degussa Ag Process for the fermentative preparation of d-pantothenic acid and/or salts thereof
WO2003004673A1 (en) * 2001-07-03 2003-01-16 Degussa Ag Process for the fermentative preparation of d-pantothenic acid and/or salts thereof
DE10132178A1 (de) * 2001-07-03 2003-01-23 Degussa Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen
US7338792B2 (en) * 2001-07-07 2008-03-04 Degussa Ag Process for the preparation of D-pantothenic acid and/or salts thereof
DE10147960A1 (de) * 2001-09-28 2003-04-10 Degussa Verfahren zur fermentativen Herstellung von D-Panthothensäure und/oder deren Salzen
CA2491145A1 (en) * 2002-07-03 2004-01-15 Basf Aktiengesellschaft Microorganisms and processes for enhanced production of pantothenate
US20070180585A1 (en) * 2004-03-17 2007-08-02 Bala Rathinasabapathi Increased stress tolerance and enhanced yield in plants
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US9238687B2 (en) 2006-04-13 2016-01-19 Chugai Seiyaku Kabushiki Kaisha Method for recombinant production of a desired polypeptide using a mammalian cell co-expressing a taurine transporter polypeptide
US20100233759A1 (en) 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
DK2186905T3 (en) 2007-08-07 2016-09-19 Chugai Pharmaceutical Co Ltd Method of Preparation of Heterogeneous Protein
RU2486245C2 (ru) * 2007-10-15 2013-06-27 Чугаи Сейяку Кабусики Кайся Способ получения клетки, способной продуцировать гетеропротеины с высоким выходом
AU2008314973C1 (en) * 2007-10-24 2014-05-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
US8741601B2 (en) 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins
CN107354142A (zh) * 2017-09-14 2017-11-17 精晶药业股份有限公司 一种L‑天门冬氨酸‑α‑脱羧酶酶液处理方法
CN109593748B (zh) * 2017-10-01 2022-03-04 宁波酶赛生物工程有限公司 工程化脱羧酶多肽及其在制备β-丙氨酸中的应用
CN113122486B (zh) * 2019-12-31 2023-06-13 江南大学 一种丙二酸的全生物合成的方法
KR102389327B1 (ko) * 2020-07-01 2022-04-20 씨제이제일제당 (주) 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도
KR102589135B1 (ko) * 2021-05-10 2023-10-12 씨제이제일제당 (주) 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도
CN113789307B (zh) * 2021-09-10 2023-08-18 浙江工业大学 一种泛酸合成酶突变体、编码基因、载体及应用
KR20240105656A (ko) * 2022-12-28 2024-07-08 씨제이제일제당 (주) 음이온 수송 단백질의 활성이 강화된 미생물 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0493060A3 (en) * 1990-12-25 1993-04-14 Takeda Chemical Industries, Ltd. Production method of d-pantothenic acid and plasmids and microorganisms thereof
JP3710497B2 (ja) * 1992-09-25 2005-10-26 ビーエーエスエフ アクチェンゲゼルシャフト Ｄ−パント酸、ｄ−パントテン酸およびそれらの塩の製造法
ATE264392T1 (de) 1995-09-13 2004-04-15 Basf Ag Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salze
DE19846499A1 (de) * 1998-10-09 2000-04-20 Degussa Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen
DE19855314A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR20070087035A (ko) * 1999-06-25 2007-08-27 바스프 악티엔게젤샤프트 대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰유전자
EP1083225A1 (de) * 1999-09-09 2001-03-14 Degussa-Hüls Aktiengesellschaft Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien

Also Published As

Publication number Publication date
ZA997406B (en) 2000-06-08
US6184007B1 (en) 2001-02-06
EP1006192A3 (de) 2003-09-17
HUP9904447A2 (hu) 2000-11-28
BR9905776A (pt) 2001-04-24
EP1006192A2 (de) 2000-06-07
CN1256314A (zh) 2000-06-14
ATE442443T1 (de) 2009-09-15
DE59915077D1 (de) 2009-10-22
JP2000228990A (ja) 2000-08-22
DE19855313A1 (de) 2000-06-08
KR20000047829A (ko) 2000-07-25
EP1006192B1 (de) 2009-09-09
SK163399A3 (en) 2000-07-11
HU9904447D0 (en) 2000-01-28
ID24149A (id) 2000-07-13
IL133214A0 (en) 2001-03-19

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