ATE264392T1 - Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salze - Google Patents
Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salzeInfo
- Publication number
- ATE264392T1 ATE264392T1 AT96930354T AT96930354T ATE264392T1 AT E264392 T1 ATE264392 T1 AT E264392T1 AT 96930354 T AT96930354 T AT 96930354T AT 96930354 T AT96930354 T AT 96930354T AT E264392 T1 ATE264392 T1 AT E264392T1
- Authority
- AT
- Austria
- Prior art keywords
- acid
- pantoic
- pct
- producing
- alanine
- Prior art date
Links
- GHOKWGTUZJEAQD-UHFFFAOYSA-N pantothenic acid Chemical compound OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 title abstract 8
- OTOIIPJYVQJATP-BYPYZUCNSA-N (R)-pantoic acid Chemical compound OCC(C)(C)[C@@H](O)C(O)=O OTOIIPJYVQJATP-BYPYZUCNSA-N 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title 1
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 abstract 6
- 229940000635 beta-alanine Drugs 0.000 abstract 3
- 239000001963 growth medium Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23506595 | 1995-09-13 | ||
| PCT/JP1996/002585 WO1997010340A1 (en) | 1995-09-13 | 1996-09-11 | Process for producing d-pantoic acid and d-pantothenic acid or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264392T1 true ATE264392T1 (de) | 2004-04-15 |
Family
ID=16980558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96930354T ATE264392T1 (de) | 1995-09-13 | 1996-09-11 | Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salze |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5932457A (de) |
| EP (1) | EP0859848B1 (de) |
| KR (1) | KR100421088B1 (de) |
| CN (1) | CN1142997C (de) |
| AT (1) | ATE264392T1 (de) |
| AU (1) | AU6943696A (de) |
| DE (1) | DE69632199T2 (de) |
| DK (1) | DK0859848T3 (de) |
| SK (1) | SK30598A3 (de) |
| WO (1) | WO1997010340A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19855313A1 (de) | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen |
| DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| AU1798300A (en) | 1998-12-25 | 2000-07-31 | Fuji Chemical Industries, Ltd. | Method for producing calcium pantothenate |
| ATE227938T1 (de) * | 1999-05-05 | 2002-12-15 | Degussa | D-pantothensäure und/oder eines ihrer salze enthaltende futtermittel-additive und verfahren zu deren herstellung |
| MXPA02003017A (es) | 1999-09-21 | 2004-09-06 | Basf Ag | Metodos y microorganismos para la produccion de panto-compuestos. |
| US8232081B2 (en) * | 1999-09-21 | 2012-07-31 | Basf Se | Methods and microorganisms for production of panto-compounds |
| DE10021515A1 (de) * | 2000-05-03 | 2001-11-08 | Degussa | Verfahren zur Herstellung von Erdalkalisalzen der D-Pantothensäure |
| DE10032349A1 (de) | 2000-07-04 | 2002-01-17 | Degussa | Rieselfähige D-Pantothensäure und/oder deren Salze enthaltende Futtermittel-Additive und Verfahren zu deren Herstellung |
| KR20030038751A (ko) * | 2000-09-20 | 2003-05-16 | 바스프 악티엔게젤샤프트 | Ｄ-판토텐산 또는 그의 염을 포함하는 동물 사료 보충물,그의 개선된 제조 방법 및 그의 용도 |
| RU2003128532A (ru) * | 2001-02-21 | 2005-03-27 | Басф Акциенгезелльшафт (De) | Способ получения d-пантотеновой кислоты и/или ее солей, используемых в качестве добавок при производстве кормов для животных |
| CN1294271C (zh) * | 2001-02-21 | 2007-01-10 | 巴斯福股份公司 | 制备作为动物饲料添加剂的d－泛酸和/或其盐的方法 |
| DE10108225A1 (de) | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
| DE10112100A1 (de) * | 2001-03-14 | 2002-09-19 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| US6623944B2 (en) | 2001-03-14 | 2003-09-23 | Degussa Ag | Process for preparation of D-pantothenic acid and/or salts thereof |
| DE10132178A1 (de) | 2001-07-03 | 2003-01-23 | Degussa | Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| EP1404840A2 (de) | 2001-07-07 | 2004-04-07 | Degussa AG | Verfahren zur herstellung von d-pantothensäure und/oder salzen davon |
| MXPA04012812A (es) * | 2002-07-03 | 2005-02-24 | Basf Ag | Microorganismos y proceso para la produccion aumentada de pantotenato. |
| CN101448950B (zh) | 2006-05-16 | 2014-02-12 | 帝斯曼知识产权资产管理有限公司 | 用于生产泛醇的工艺 |
| CN109705065B (zh) * | 2018-12-29 | 2022-10-14 | 上海应用技术大学 | 一种不对称催化合成d-(-)-泛解酸内酯的方法 |
| KR102389327B1 (ko) * | 2020-07-01 | 2022-04-20 | 씨제이제일제당 (주) | 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도 |
| CN112592290B (zh) * | 2020-12-14 | 2023-08-11 | 广安摩珈生物科技有限公司 | 泛酸钙粗品纯化方法 |
| CN115595314B (zh) * | 2022-03-07 | 2025-06-24 | 中国科学院微生物研究所 | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
| KR102922207B1 (ko) * | 2023-01-19 | 2026-02-02 | 씨제이제일제당 (주) | 고순도의 d-판토텐산 염을 높은 수율로 얻는 방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2748418B2 (ja) * | 1988-08-03 | 1998-05-06 | 味の素株式会社 | 組換えｄｎａ、該組換えｄｎａを有する微生物 |
| EP0493060A3 (en) * | 1990-12-25 | 1993-04-14 | Takeda Chemical Industries, Ltd. | Production method of d-pantothenic acid and plasmids and microorganisms thereof |
| JP3710497B2 (ja) * | 1992-09-25 | 2005-10-26 | ビーエーエスエフ アクチェンゲゼルシャフト | Ｄ−パント酸、ｄ−パントテン酸およびそれらの塩の製造法 |
-
1996
- 1996-09-11 AU AU69436/96A patent/AU6943696A/en not_active Abandoned
- 1996-09-11 EP EP96930354A patent/EP0859848B1/de not_active Expired - Lifetime
- 1996-09-11 DE DE69632199T patent/DE69632199T2/de not_active Expired - Lifetime
- 1996-09-11 KR KR19980701859A patent/KR100421088B1/ko not_active Expired - Fee Related
- 1996-09-11 WO PCT/JP1996/002585 patent/WO1997010340A1/en not_active Ceased
- 1996-09-11 SK SK305-98A patent/SK30598A3/sk unknown
- 1996-09-11 US US08/750,983 patent/US5932457A/en not_active Expired - Fee Related
- 1996-09-11 AT AT96930354T patent/ATE264392T1/de not_active IP Right Cessation
- 1996-09-11 CN CNB961981849A patent/CN1142997C/zh not_active Expired - Fee Related
- 1996-09-11 DK DK96930354T patent/DK0859848T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| CN1142997C (zh) | 2004-03-24 |
| AU6943696A (en) | 1997-04-01 |
| DE69632199D1 (de) | 2004-05-19 |
| DK0859848T3 (da) | 2004-08-09 |
| DE69632199T2 (de) | 2005-04-21 |
| KR100421088B1 (ko) | 2004-06-04 |
| KR19990044609A (ko) | 1999-06-25 |
| WO1997010340A1 (en) | 1997-03-20 |
| US5932457A (en) | 1999-08-03 |
| EP0859848B1 (de) | 2004-04-14 |
| CN1201491A (zh) | 1998-12-09 |
| EP0859848A1 (de) | 1998-08-26 |
| SK30598A3 (en) | 1999-01-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0859848 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |