IL80702A0 - Human manganese superoxide dismutase cdna and its expression in bacteria,and method of recovering enzymatically active human manganese superoxide dismutase - Google Patents

Human manganese superoxide dismutase cdna and its expression in bacteria,and method of recovering enzymatically active human manganese superoxide dismutase

Info

Publication number
IL80702A0
IL80702A0 IL80702A IL8070286A IL80702A0 IL 80702 A0 IL80702 A0 IL 80702A0 IL 80702 A IL80702 A IL 80702A IL 8070286 A IL8070286 A IL 8070286A IL 80702 A0 IL80702 A0 IL 80702A0
Authority
IL
Israel
Prior art keywords
superoxide dismutase
manganese superoxide
human manganese
bacteria
expression
Prior art date
Application number
IL80702A
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Priority to IL10644986A priority Critical patent/IL106449A/en
Publication of IL80702A0 publication Critical patent/IL80702A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL80702A 1985-11-22 1986-11-20 Human manganese superoxide dismutase cdna and its expression in bacteria,and method of recovering enzymatically active human manganese superoxide dismutase IL80702A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL10644986A IL106449A (en) 1985-11-22 1986-11-20 Human manganese superoxide dismutase cDNA

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80109085A 1985-11-22 1985-11-22
US90705186A 1986-09-12 1986-09-12

Publications (1)

Publication Number Publication Date
IL80702A0 true IL80702A0 (en) 1987-02-27

Family

ID=27122291

Family Applications (2)

Application Number Title Priority Date Filing Date
IL10644986A IL106449A (en) 1985-11-22 1986-11-20 Human manganese superoxide dismutase cDNA
IL80702A IL80702A0 (en) 1985-11-22 1986-11-20 Human manganese superoxide dismutase cdna and its expression in bacteria,and method of recovering enzymatically active human manganese superoxide dismutase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL10644986A IL106449A (en) 1985-11-22 1986-11-20 Human manganese superoxide dismutase cDNA

Country Status (21)

Country Link
JP (2) JP2609449B2 (en)
AT (1) AT400443B (en)
AU (1) AU607897B2 (en)
BE (1) BE905796A (en)
CA (1) CA1341362C (en)
CH (1) CH676990A5 (en)
DE (1) DE3639725C2 (en)
DK (1) DK534686A (en)
ES (1) ES2003518A6 (en)
FI (1) FI90353C (en)
FR (1) FR2590591B1 (en)
GB (1) GB2183658B (en)
GR (1) GR862713B (en)
HK (1) HK75195A (en)
IE (1) IE59498B1 (en)
IL (2) IL106449A (en)
IT (1) IT1205418B (en)
LU (1) LU86676A1 (en)
NL (1) NL8602960A (en)
PT (1) PT83792B (en)
SE (1) SE8604884L (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610520B1 (en) 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS62215532A (en) * 1986-03-18 1987-09-22 Ube Ind Ltd anti-inflammatory agent
JPH0643341B2 (en) * 1986-03-27 1994-06-08 宇部興産株式会社 Organ function improving agent
JPH0643340B2 (en) * 1986-09-03 1994-06-08 宇部興産株式会社 Ischemic heart disease drug
JPS6377822A (en) * 1986-09-18 1988-04-08 Ube Ind Ltd Organ function improver
US6326003B1 (en) 1986-10-14 2001-12-04 Chiron Corporation Manganese superoxide dismutase cloning and expression in microorganisms
ES2083357T3 (en) * 1987-03-14 1996-04-16 Boehringer Ingelheim Int HUMAN MANGANESE-SUPEROXIDE-DISMUTASE (HMN-SOD).
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
DE3854678T2 (en) * 1987-03-27 1996-06-13 Bio Technology General Corp Human manganese superoxide dismutase and treatment procedure.
JPH01233228A (en) * 1988-03-11 1989-09-19 Toyo Jozo Co Ltd Metastasis preventive of malignant tumor cells
US5772996A (en) * 1990-08-03 1998-06-30 Public Health Laboratory Service Board Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
DE4038563A1 (en) * 1990-12-04 1992-06-11 Gruenenthal Gmbh USE OF SUPEROXIDE DISMUTASES FOR PROPHYLAXIS AND / OR TREATMENT OF ORGAN FAILURE IN RISK PATIENTS WITH POLYTRAUMA
ATE209928T1 (en) * 1992-09-09 2001-12-15 Bio Technology General Corp USE OF MANGANEOUS SUPEROXIDE DISMUTASE (MN-SOD) FOR THE PRODUCTION OF MEDICINAL PRODUCTS FOR THE TREATMENT OF DISEASES IN LOW DOSES
DE4239877C1 (en) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilized superoxide dismutase (SOD) composition
WO2025178510A1 (en) * 2024-02-21 2025-08-28 Евгений Владимирович ГРИГОРЬЕВ Method of using superoxide dismutase 2 as an antioxidant in ultra-low doses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio- Technology General Corp METHOD FOR OBTAINING A POLYPEPTIDE WITH SUPEROXIDE DISMUTASE ACTIVITY
DE3486452T2 (en) * 1983-10-03 1997-11-06 Chiron Corp., Emeryville, Calif. Superoxide dismutase and its expression in microorganisms

Also Published As

Publication number Publication date
IL106449A0 (en) 1993-11-15
DK534686A (en) 1987-05-23
IE59498B1 (en) 1994-03-09
AU6497586A (en) 1987-05-28
FI90353B (en) 1993-10-15
ATA308986A (en) 1995-05-15
GB8627294D0 (en) 1986-12-17
CH676990A5 (en) 1991-03-28
FR2590591A1 (en) 1987-05-29
BE905796A (en) 1987-03-16
JPH08289792A (en) 1996-11-05
GB2183658B (en) 1990-04-25
LU86676A1 (en) 1987-05-04
JPS62289187A (en) 1987-12-16
IE862851L (en) 1987-05-22
DE3639725C2 (en) 1998-02-19
JP2609449B2 (en) 1997-05-14
GB2183658A (en) 1987-06-10
AU607897B2 (en) 1991-03-21
ES2003518A6 (en) 1988-11-01
SE8604884L (en) 1987-05-23
SE8604884D0 (en) 1986-11-14
FR2590591B1 (en) 1989-12-01
NL8602960A (en) 1987-06-16
DK534686D0 (en) 1986-11-07
CA1341362C (en) 2002-05-28
JP2967557B2 (en) 1999-10-25
IT8667865A0 (en) 1986-11-21
IL106449A (en) 1997-02-18
DE3639725A1 (en) 1987-07-23
GR862713B (en) 1987-03-24
AT400443B (en) 1995-12-27
FI864756A0 (en) 1986-11-21
FI864756A7 (en) 1987-05-23
FI90353C (en) 1994-01-25
PT83792B (en) 1989-01-17
IT1205418B (en) 1989-03-15
HK75195A (en) 1995-05-26
PT83792A (en) 1986-12-01

Similar Documents

Publication Publication Date Title
IL106449A0 (en) Human manganese superoxide dismutase cdna and its expression in bacteria,and method of recovering enzymatically active human manganese superoxide dismutase
CS938286A2 (en) Fungicide and method of active substances production
CA1268123C (en) Dietary products and uses comprising methylsulfonylmethane
CS265687A2 (en) Fungicide and method of its active substances production
GR861228B (en) Ascorbic acid derivatives production and use therefor
AU557784B2 (en) Detection of peroxidase activity and/or hemoglobin
GR861717B (en) Modified enzymes production and use thereof
CS872487A2 (en) Fungicide and method of active substances production
ZA864610B (en) Use of benzamido-azabicyclo compounds in the treatment of migraine,nausea,vomiting and cardiac arrhythmia
PT83301B (en) Expression of superoxide dismutase in eukaryotic cells and process for obtaining the same
ZA868610B (en) Human manganese superoxide dismutase cdna,its expression in bacteria and method of recovering enzymatically active human manganese superoxide dismutase
CS335287A2 (en) Fungicide and method of its active substance production
CS673586A2 (en) Fungicide and method of its active substance production
AU2722888A (en) Selective immobilization and detection of mycotoxins in solution
AU580635B2 (en) Improvements in or relating to the treatment of trees and bushes
CS335387A2 (en) Fungicide and method of its active substance production
EP0200527A3 (en) Norfloxacin salt
AU92306S (en) Buddha figurine
GB2172704B (en) Antigenically active protein and its use in the diagnosis of gonorrhoea
GB2208863B (en) Production of 2-methyl-5-isopropyl-hexa-2,5-dien-1-al and of 2-methyl-5-isopropyl-hexa-2,4-dien-1-al in microorganisms
IL120245A0 (en) Enzymatically active analogs and mutants of human manganese superoxide dismutase
GB2197801B (en) Improvements in and relating to pressure swing oxygen generation systems
CS103787A2 (en) Fungicide and method of active substances production
HUT41633A (en) Utilization of alpha-keto-carboxylic acid hydrazides and -oximes in diseases of the heart and circulation
PH24284A (en) Method and composition for reducing blood cholesterol in humans or animals

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed