HK75195A - Human manganese superoxide dismutase analog, plasmid for its expression and method of recovering it in enzymatically active form - Google Patents

Human manganese superoxide dismutase analog, plasmid for its expression and method of recovering it in enzymatically active form

Info

Publication number
HK75195A
HK75195A HK75195A HK75195A HK75195A HK 75195 A HK75195 A HK 75195A HK 75195 A HK75195 A HK 75195A HK 75195 A HK75195 A HK 75195A HK 75195 A HK75195 A HK 75195A
Authority
HK
Hong Kong
Prior art keywords
plasmid
recovering
expression
active form
superoxide dismutase
Prior art date
Application number
HK75195A
Inventor
Jacob R Hartman
Yaffa Beck
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Publication of HK75195A publication Critical patent/HK75195A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK75195A 1985-11-22 1995-05-18 Human manganese superoxide dismutase analog, plasmid for its expression and method of recovering it in enzymatically active form HK75195A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80109085A 1985-11-22 1985-11-22
US90705186A 1986-09-12 1986-09-12

Publications (1)

Publication Number Publication Date
HK75195A true HK75195A (en) 1995-05-26

Family

ID=27122291

Family Applications (1)

Application Number Title Priority Date Filing Date
HK75195A HK75195A (en) 1985-11-22 1995-05-18 Human manganese superoxide dismutase analog, plasmid for its expression and method of recovering it in enzymatically active form

Country Status (21)

Country Link
JP (2) JP2609449B2 (en)
AT (1) AT400443B (en)
AU (1) AU607897B2 (en)
BE (1) BE905796A (en)
CA (1) CA1341362C (en)
CH (1) CH676990A5 (en)
DE (1) DE3639725C2 (en)
DK (1) DK534686A (en)
ES (1) ES2003518A6 (en)
FI (1) FI90353C (en)
FR (1) FR2590591B1 (en)
GB (1) GB2183658B (en)
GR (1) GR862713B (en)
HK (1) HK75195A (en)
IE (1) IE59498B1 (en)
IL (2) IL106449A (en)
IT (1) IT1205418B (en)
LU (1) LU86676A1 (en)
NL (1) NL8602960A (en)
PT (1) PT83792B (en)
SE (1) SE8604884L (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610520B1 (en) 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS62215532A (en) * 1986-03-18 1987-09-22 Ube Ind Ltd Anti-inflammatory drug
JPH0643341B2 (en) * 1986-03-27 1994-06-08 宇部興産株式会社 Organ function improving agent
JPH0643340B2 (en) * 1986-09-03 1994-06-08 宇部興産株式会社 Ischemic heart disease drug
JPS6377822A (en) * 1986-09-18 1988-04-08 Ube Ind Ltd Organ function improver
US6326003B1 (en) 1986-10-14 2001-12-04 Chiron Corporation Manganese superoxide dismutase cloning and expression in microorganisms
EP0676472A1 (en) * 1987-03-14 1995-10-11 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Human manganese superoxide dismutase (hMn-SOD)
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
ATE130196T1 (en) * 1987-03-27 1995-12-15 Bio Technology General Corp HUMAN MANGANESE SUPEROXIDE DISMUTASE AND TREATMENT METHODS.
JPH01233228A (en) * 1988-03-11 1989-09-19 Toyo Jozo Co Ltd Metastasis preventive of malignant tumor cells
US5772996A (en) * 1990-08-03 1998-06-30 Public Health Laboratory Service Board Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
DE4038563A1 (en) * 1990-12-04 1992-06-11 Gruenenthal Gmbh USE OF SUPEROXIDE DISMUTASES FOR PROPHYLAXIS AND / OR TREATMENT OF ORGAN FAILURE IN RISK PATIENTS WITH POLYTRAUMA
DK0587055T3 (en) * 1992-09-09 2002-04-02 Bio Technology General Corp Use of manganese superoxide dismutase (Mn-SOD) in the manufacture of drugs for the treatment of low-dose diseases
DE4239877C1 (en) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilized superoxide dismutase (SOD) composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio- Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
DE3486493T2 (en) * 1983-10-03 2003-05-22 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Cloning of superoxide dismutase and expression in microorganisms

Also Published As

Publication number Publication date
FI864756A (en) 1987-05-23
IT8667865A0 (en) 1986-11-21
IT1205418B (en) 1989-03-15
FI90353B (en) 1993-10-15
JP2609449B2 (en) 1997-05-14
FR2590591B1 (en) 1989-12-01
GB2183658A (en) 1987-06-10
FR2590591A1 (en) 1987-05-29
AU607897B2 (en) 1991-03-21
IE59498B1 (en) 1994-03-09
GB2183658B (en) 1990-04-25
IL106449A (en) 1997-02-18
CA1341362C (en) 2002-05-28
LU86676A1 (en) 1987-05-04
AU6497586A (en) 1987-05-28
DK534686D0 (en) 1986-11-07
NL8602960A (en) 1987-06-16
DE3639725C2 (en) 1998-02-19
GB8627294D0 (en) 1986-12-17
PT83792B (en) 1989-01-17
AT400443B (en) 1995-12-27
PT83792A (en) 1986-12-01
FI864756A0 (en) 1986-11-21
IL106449A0 (en) 1993-11-15
BE905796A (en) 1987-03-16
SE8604884L (en) 1987-05-23
ATA308986A (en) 1995-05-15
JPS62289187A (en) 1987-12-16
JPH08289792A (en) 1996-11-05
DE3639725A1 (en) 1987-07-23
FI90353C (en) 1994-01-25
IL80702A0 (en) 1987-02-27
JP2967557B2 (en) 1999-10-25
IE862851L (en) 1987-05-22
ES2003518A6 (en) 1988-11-01
CH676990A5 (en) 1991-03-28
GR862713B (en) 1987-03-24
SE8604884D0 (en) 1986-11-14
DK534686A (en) 1987-05-23

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)