DK456686A - Stabiliseret human prourokinase - Google Patents
Stabiliseret human prourokinase Download PDFInfo
- Publication number
- DK456686A DK456686A DK456686A DK456686A DK456686A DK 456686 A DK456686 A DK 456686A DK 456686 A DK456686 A DK 456686A DK 456686 A DK456686 A DK 456686A DK 456686 A DK456686 A DK 456686A
- Authority
- DK
- Denmark
- Prior art keywords
- stabilized human
- human prourokinase
- prourokinase
- stabilized
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1103385 | 1985-01-25 | ||
JP8361185 | 1985-04-20 | ||
JP15929485 | 1985-07-20 | ||
PCT/JP1986/000031 WO1986004351A1 (en) | 1985-01-25 | 1986-01-24 | Stabilized human prourokinase |
Publications (2)
Publication Number | Publication Date |
---|---|
DK456686D0 DK456686D0 (da) | 1986-09-24 |
DK456686A true DK456686A (da) | 1986-09-24 |
Family
ID=27279225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK456686A DK456686A (da) | 1985-01-25 | 1986-09-24 | Stabiliseret human prourokinase |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0210279B1 (da) |
AU (1) | AU5390286A (da) |
DE (1) | DE3680838D1 (da) |
DK (1) | DK456686A (da) |
WO (1) | WO1986004351A1 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5219569A (en) * | 1985-04-22 | 1993-06-15 | Genentech, Inc. | Protease resistant urokinase |
US5204255A (en) * | 1986-01-31 | 1993-04-20 | Sagami Chemical Research Center | Hybrid tissue plasminogen activator/urokinase polypeptides |
EP0236040A3 (en) * | 1986-02-26 | 1989-05-03 | Collaborative Research Inc. | Amino acid modified prourokinase and method of preparation |
JPH0761266B2 (ja) * | 1986-07-03 | 1995-07-05 | 株式会社ミドリ十字 | 変異ヒトプロウロキナ−ゼ |
WO1988005081A2 (en) * | 1986-12-30 | 1988-07-14 | Cetus Corporation | Novel plasminogen activator |
MY103358A (en) * | 1987-04-15 | 1993-06-30 | Novartis Ag | Process for the production of protiens. |
WO1989001513A1 (en) * | 1987-08-19 | 1989-02-23 | Sagami Chemical Research Center | Fast-acting prourokinase |
DE3735916A1 (de) * | 1987-10-23 | 1989-05-03 | Basf Ag | Neue polypeptide, ihre herstellung und verwendung |
GB8823833D0 (en) * | 1988-10-11 | 1988-11-16 | Erba Carlo Spa | Production of human prourokinase |
JPH0322979A (ja) * | 1989-06-19 | 1991-01-31 | Kyowa Hakko Kogyo Co Ltd | 新規プラスミノーゲン活性化因子 |
US5240845A (en) * | 1989-07-11 | 1993-08-31 | Otsuka Pharmaceutical Factory, Ltd. | Mutated streptokinase proteins |
IE901849A1 (en) * | 1989-07-19 | 1991-06-19 | Gruenenthal Gmbh | Plasmids, their preparation and their use in the manufacture¹of a plasminogen activator |
US5087572A (en) * | 1989-12-01 | 1992-02-11 | Genentech, Inc. | Dna encoding human plasminogen modified at the cleavage site |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4370417A (en) * | 1980-04-03 | 1983-01-25 | Abbott Laboratories | Recombinant deoxyribonucleic acid which codes for plasminogen activator |
JPS58148899A (ja) * | 1982-02-27 | 1983-09-05 | Green Cross Corp:The | ウロキナ−ゼ様蛋白質をコ−ドするmRNA及びその製造法 |
GR78180B (da) * | 1982-04-15 | 1984-09-26 | Genentech Inc | |
JPS60180519A (ja) * | 1984-02-25 | 1985-09-14 | 千葉 光律 | サイレージの製造装置 |
-
1986
- 1986-01-24 AU AU53902/86A patent/AU5390286A/en not_active Abandoned
- 1986-01-24 WO PCT/JP1986/000031 patent/WO1986004351A1/ja active IP Right Grant
- 1986-01-24 EP EP19860900852 patent/EP0210279B1/en not_active Expired
- 1986-01-24 DE DE8686900852T patent/DE3680838D1/de not_active Expired - Lifetime
- 1986-09-24 DK DK456686A patent/DK456686A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK456686D0 (da) | 1986-09-24 |
EP0210279B1 (en) | 1991-08-14 |
EP0210279A1 (en) | 1987-02-04 |
DE3680838D1 (de) | 1991-09-19 |
WO1986004351A1 (en) | 1986-07-31 |
EP0210279A4 (en) | 1987-06-19 |
AU5390286A (en) | 1986-08-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |