IN2014DN09073A - - Google Patents
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- Publication number
- IN2014DN09073A IN2014DN09073A IN9073DEN2014A IN2014DN09073A IN 2014DN09073 A IN2014DN09073 A IN 2014DN09073A IN 9073DEN2014 A IN9073DEN2014 A IN 9073DEN2014A IN 2014DN09073 A IN2014DN09073 A IN 2014DN09073A
- Authority
- IN
- India
- Prior art keywords
- methods
- disease
- diagnose
- practicing
- toxicity
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000007431 microscopic evaluation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/549—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic with antigen or antibody entrapped within the carrier
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N2001/4038—Concentrating samples electric methods, e.g. electromigration, electrophoresis, ionisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261681551P | 2012-08-09 | 2012-08-09 | |
| PCT/US2013/031066 WO2014025392A1 (en) | 2012-08-09 | 2013-03-13 | Methods and compositions for preparing biological specimens for microscopic analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN09073A true IN2014DN09073A (de) | 2015-05-22 |
Family
ID=50068460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN9073DEN2014 IN2014DN09073A (de) | 2012-08-09 | 2013-03-13 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10545075B2 (de) |
| EP (2) | EP2883030B1 (de) |
| JP (1) | JP6228205B2 (de) |
| KR (1) | KR102148747B1 (de) |
| CN (1) | CN104350372B (de) |
| AU (1) | AU2013300171B2 (de) |
| HK (1) | HK1204677A1 (de) |
| IN (1) | IN2014DN09073A (de) |
| WO (1) | WO2014025392A1 (de) |
Families Citing this family (125)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| JP2014531908A (ja) | 2011-10-14 | 2014-12-04 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 構造アッセンブリによる配列決定 |
| EP3425063B9 (de) | 2011-12-22 | 2023-10-04 | President and Fellows of Harvard College | Verfahren zum nachweis von analyten |
| US11021737B2 (en) | 2011-12-22 | 2021-06-01 | President And Fellows Of Harvard College | Compositions and methods for analyte detection |
| US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
| KR102148747B1 (ko) | 2012-08-09 | 2020-08-27 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 | 현미경적 분석을 위한 생물학적 표본을 준비하기 위한 방법과 조성물 |
| EP2971184B1 (de) | 2013-03-12 | 2019-04-17 | President and Fellows of Harvard College | Verfahren zur erzeugung einer dreidimensionalen nukleinsäure mit matrix |
| DE102013205115A1 (de) * | 2013-03-22 | 2014-09-25 | Leica Microsystems Cms Gmbh | SPIM-Anordnung |
| CA2916660C (en) | 2013-06-25 | 2022-05-17 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| DE102013216934A1 (de) * | 2013-08-26 | 2015-02-26 | Leica Microsystems Cms Gmbh | Verfahren und Vorrichtung zur Erhöhung der optischen Transparenz von Bereichen einer Gewebeprobe |
| US10794802B2 (en) * | 2013-09-20 | 2020-10-06 | California Institute Of Technology | Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping |
| EP3047271B1 (de) * | 2013-09-20 | 2022-05-11 | California Institute Of Technology | Verfahren zur phänotypisierung von intaktem ganzen gewebe |
| CN103558055B (zh) * | 2013-09-29 | 2016-01-06 | 中国疾病预防控制中心病毒病预防控制所 | 一种针对感染病毒的病变细胞的定位超薄切片方法 |
| JP6456969B2 (ja) * | 2014-02-21 | 2019-01-23 | マサチューセッツ インスティテュート オブ テクノロジー | 膨張顕微鏡法 |
| WO2015154000A1 (en) * | 2014-04-04 | 2015-10-08 | Massachusetts Institute Of Technology | Active transport of charged molecules into, within, and/or from charged matrices |
| KR20170013855A (ko) * | 2014-05-30 | 2017-02-07 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 | 큰 손상되지 않은 조직 샘플들을 이미징하기 위한 방법들 및 디바이스들 |
| EP3168290B1 (de) * | 2014-07-07 | 2021-12-08 | Logos Biosystems, Inc. | Vorrichtung zur klärung von gewebe mittels elektrophorese |
| CN106715768B (zh) | 2014-07-30 | 2020-06-16 | 哈佛学院院长及董事 | 用于测定核酸的系统和方法 |
| US10571371B2 (en) | 2014-08-07 | 2020-02-25 | Wake Forest University Health Sciences | Compositions and methods for clearing a biological sample |
| KR101563826B1 (ko) * | 2014-12-31 | 2015-10-28 | 계명대학교 산학협력단 | 조직 투명화 방법 |
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| US10774374B2 (en) | 2015-04-10 | 2020-09-15 | Spatial Transcriptomics AB and Illumina, Inc. | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US10526649B2 (en) | 2015-04-14 | 2020-01-07 | Massachusetts Institute Of Technology | Augmenting in situ nucleic acid sequencing of expanded biological samples with in vitro sequence information |
| US11408890B2 (en) | 2015-04-14 | 2022-08-09 | Massachusetts Institute Of Technology | Iterative expansion microscopy |
| US10059990B2 (en) | 2015-04-14 | 2018-08-28 | Massachusetts Institute Of Technology | In situ nucleic acid sequencing of expanded biological samples |
| CN106198990A (zh) * | 2015-04-30 | 2016-12-07 | 上海交通大学 | 一种对组织样本进行免疫标记的方法 |
| CN104965016A (zh) * | 2015-06-15 | 2015-10-07 | 南昌大学 | 一体化的生物组织透明装置 |
| WO2017027367A1 (en) * | 2015-08-07 | 2017-02-16 | Massachusetts Institute Of Technology | Nanoscale imaging of proteins and nucleic acids via expansion microscopy |
| CA2994957A1 (en) * | 2015-08-07 | 2017-02-16 | Massachusetts Institute Of Technology | Protein retention expansion microscopy |
| WO2017031249A1 (en) * | 2015-08-17 | 2017-02-23 | California Institute Of Technology | Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping |
| WO2017075265A1 (en) * | 2015-10-28 | 2017-05-04 | The Broad Institute, Inc. | Multiplex analysis of single cell constituents |
| EP3371329A4 (de) | 2015-11-03 | 2019-06-19 | President and Fellows of Harvard College | Verfahren und vorrichtung zur volumetrischen bildgebung einer dreidimensionalen nukleinsäurehaltigen matrix |
| JP2019507352A (ja) * | 2015-12-02 | 2019-03-14 | クリアライト ダイアグノスティックス リミテッド ライアビリティ カンパニー | 癌の検出およびモニタリングのための腫瘍組織サンプルの調製および分析のための方法 |
| RU2727554C2 (ru) | 2015-12-23 | 2020-07-22 | Конинклейке Филипс Н.В. | Флуоресцентный калибровочный слайд |
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| WO2017139501A1 (en) * | 2016-02-10 | 2017-08-17 | The Board Of Trustees Of The Leland Stanford Junior University | Rna fixation and detection in clarity-based hydrogel tissue |
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| US11397140B2 (en) * | 2016-04-29 | 2022-07-26 | Massachusetts Institute Of Technology | Methods for reversible and tunable tissue magnification |
| US10281386B2 (en) * | 2016-05-11 | 2019-05-07 | Bonraybio Co., Ltd. | Automated testing apparatus |
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| EP3252452A1 (de) | 2016-05-25 | 2017-12-06 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur abbildung und analyse einer biologischen probe |
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| WO2018155925A2 (ko) * | 2017-02-27 | 2018-08-30 | 고려대학교 산학협력단 | 하이드로겔 중합체를 이용한 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직 |
| TWI620927B (zh) * | 2017-04-21 | 2018-04-11 | 胡宇光 | 神經組織樣本染色之方法及套組與顯現神經元之方法 |
| WO2018218150A1 (en) | 2017-05-26 | 2018-11-29 | President And Fellows Of Harvard College | Systems and methods for high-throughput image-based screening |
| MX2017008919A (es) * | 2017-07-05 | 2018-03-01 | Gabriela Reyes Fuchs Carmen | Proceso para formar una imagen a color de materiales incinerados mediante tecnicas de microscopia. |
| US11719606B2 (en) | 2017-07-06 | 2023-08-08 | University Public Corporation Osaka | Method and reagent for clearing biological tissue |
| KR101996722B1 (ko) * | 2017-07-07 | 2019-07-04 | 재단법인대구경북과학기술원 | 다채널 박막전극을 이용한 전기적 생체분자 이동방법 |
| WO2019023214A1 (en) | 2017-07-25 | 2019-01-31 | Massachusetts Institute Of Technology | ATAC IN SITU SEQUENCING |
| EP3668998A1 (de) | 2017-10-06 | 2020-06-24 | Cartana AB | Rna-template-ligation |
| KR102200618B1 (ko) * | 2018-01-12 | 2021-01-08 | 재단법인대구경북과학기술원 | 설포베타인계 쯔비터이온성 계면활성제를 포함하는 생물학적 분자의 조직침투용 조성물 및 이의 용도 |
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| WO2020011735A2 (en) | 2018-07-09 | 2020-01-16 | Universität Zürich | Systems, apparatuses, and methods for preparation of tissue samples |
| EP3836967A4 (de) | 2018-07-30 | 2022-06-15 | ReadCoor, LLC | Verfahren und systeme zur probenverarbeitung oder -analyse |
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| US11435302B2 (en) * | 2018-11-13 | 2022-09-06 | The Trustees Of Princeton University | X-ray assisted electron microscopy staining procedure |
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| CN109781493A (zh) * | 2018-12-26 | 2019-05-21 | 华中科技大学苏州脑空间信息研究院 | 一种可长时间连续精细切削成像的生物组织水凝胶包埋方法 |
| CN109612811A (zh) * | 2018-12-26 | 2019-04-12 | 华中科技大学苏州脑空间信息研究院 | 一种保护生物组织结构和荧光的水凝胶包埋方法 |
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| EP4163617A1 (de) | 2023-04-12 |
| KR102148747B1 (ko) | 2020-08-27 |
| AU2013300171A1 (en) | 2014-11-06 |
| US20170219465A1 (en) | 2017-08-03 |
| EP2883030B1 (de) | 2022-08-31 |
| EP2883030A4 (de) | 2016-03-02 |
| CN104350372B (zh) | 2018-03-02 |
| KR20150043241A (ko) | 2015-04-22 |
| HK1204677A1 (en) | 2015-11-27 |
| JP2015533210A (ja) | 2015-11-19 |
| JP6228205B2 (ja) | 2017-11-08 |
| CN104350372A (zh) | 2015-02-11 |
| US20150144490A1 (en) | 2015-05-28 |
| AU2013300171B2 (en) | 2017-09-14 |
| WO2014025392A1 (en) | 2014-02-13 |
| US20210215581A1 (en) | 2021-07-15 |
| US10545075B2 (en) | 2020-01-28 |
| EP2883030A1 (de) | 2015-06-17 |
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