DE602005023426D1 - Hybridisierungskettenreaktion - Google Patents
HybridisierungskettenreaktionInfo
- Publication number
- DE602005023426D1 DE602005023426D1 DE602005023426T DE602005023426T DE602005023426D1 DE 602005023426 D1 DE602005023426 D1 DE 602005023426D1 DE 602005023426 T DE602005023426 T DE 602005023426T DE 602005023426 T DE602005023426 T DE 602005023426T DE 602005023426 D1 DE602005023426 D1 DE 602005023426D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- chain reaction
- initiator
- hybridization chain
- monomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55614704P | 2004-03-25 | 2004-03-25 | |
| PCT/US2005/009471 WO2005098049A2 (en) | 2004-03-25 | 2005-03-22 | Hybridization chain reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005023426D1 true DE602005023426D1 (de) | 2010-10-21 |
Family
ID=35125688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005023426T Active DE602005023426D1 (de) | 2004-03-25 | 2005-03-22 | Hybridisierungskettenreaktion |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7632641B2 (de) |
| EP (1) | EP1730161B1 (de) |
| AT (1) | ATE480550T1 (de) |
| DE (1) | DE602005023426D1 (de) |
| WO (1) | WO2005098049A2 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005023426D1 (de) | 2004-03-25 | 2010-10-21 | California Inst Of Techn | Hybridisierungskettenreaktion |
| US7727721B2 (en) | 2005-03-08 | 2010-06-01 | California Institute Of Technology | Hybridization chain reaction amplification for in situ imaging |
| US20060234261A1 (en) * | 2005-03-08 | 2006-10-19 | Pierce Niles A | Colorimetric readout of hybridization chain reaction |
| WO2007044727A2 (en) * | 2005-10-07 | 2007-04-19 | California Institute Of Technology | Pkr activation via hybridization chain reaction |
| US8318921B2 (en) * | 2007-03-01 | 2012-11-27 | California Institute Of Technology | Triggered RNAi |
| US8043810B2 (en) * | 2007-05-02 | 2011-10-25 | Eagle Eye Research, Inc. | Analyte detection using autocatalytic chain reactions |
| EP2155770B1 (de) * | 2007-05-16 | 2013-10-16 | California Institute of Technology | Vielseitiges nukleinsäure-haarnadel-motiv zur programmierung biomolekularer selbstanordnungspfade |
| US8497364B2 (en) | 2008-02-27 | 2013-07-30 | California Institute Of Technology | Triggered RNAi |
| US20100021904A1 (en) * | 2008-05-21 | 2010-01-28 | Pierce Niles A | Shielded cross-linking probes |
| US8241854B2 (en) * | 2008-05-22 | 2012-08-14 | California Institute Of Technology | Triggered RNAi |
| US20100021901A1 (en) * | 2008-05-22 | 2010-01-28 | Peng Yin | Compositions and methods for detecting analytes |
| CN102196773B (zh) * | 2008-10-23 | 2013-09-25 | 皇家飞利浦电子股份有限公司 | 分子成像 |
| US8658780B2 (en) | 2010-05-18 | 2014-02-25 | California Institute Of Technology | Triggered covalent probes for imaging and silencing genetic expression |
| US8877438B2 (en) | 2010-07-20 | 2014-11-04 | California Institute Of Technology | Self-assembled polynucleotide structure |
| US9834439B2 (en) | 2010-07-20 | 2017-12-05 | California Institute Of Technology | Biomolecular self-assembly |
| US8962241B2 (en) | 2010-07-20 | 2015-02-24 | California Institute Of Technology | Triggered molecular geometry based bioimaging probes |
| EP2444501A1 (de) | 2010-10-22 | 2012-04-25 | Université de Fribourg | Sensor |
| US9284602B2 (en) * | 2010-10-27 | 2016-03-15 | President And Fellows Of Harvard College | Compositions of toehold primer duplexes and methods of use |
| CN102653789A (zh) * | 2012-03-14 | 2012-09-05 | 河北大学 | 一种生物分子的定量检测方法 |
| EP4163617A1 (de) | 2012-08-09 | 2023-04-12 | The Board of Trustees of the Leland Stanford Junior University | Verfahren und zusammensetzungen zur herstellung biologischer proben zur mikroskopischen untersuchung |
| WO2014169216A2 (en) | 2013-04-11 | 2014-10-16 | Carnegie Mellon University | TEMPLATE-DIRECTED γPNA SYNTHESIS AND γPNA TARGETING COMPOUNDS |
| US10370415B2 (en) | 2013-04-11 | 2019-08-06 | Carnegie Mellon University | Divalent nucleobase compounds and uses therefor |
| US9856472B2 (en) | 2013-07-01 | 2018-01-02 | California Institute Of Technology | Small conditional RNAs |
| CN106103818A (zh) * | 2013-12-16 | 2016-11-09 | 威廉马歇莱思大学 | 精细调节的超特异性核酸杂交探针 |
| CN104726548A (zh) * | 2013-12-20 | 2015-06-24 | 深圳先进技术研究院 | 一种基于杂交链式反应的dna、rna或蛋白质检测探针、检测方法及试剂盒 |
| GB201401885D0 (en) | 2014-02-04 | 2014-03-19 | Olink Ab | Proximity assay with detection based on hybridisation chain reaction (HCR) |
| US10851407B2 (en) | 2014-05-08 | 2020-12-01 | Carnegie Mellon University | Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor |
| ES2961374T3 (es) | 2015-04-24 | 2024-03-11 | Atila Biosystems Incorporated | Amplificación con cebadores de composición de nucleótidos limitada |
| CA3038658A1 (en) | 2015-12-14 | 2017-06-22 | The Penn State Research Foundation | Polymer-based signal amplification for protein and cell detection |
| US11254974B2 (en) | 2016-02-10 | 2022-02-22 | The Board Of Trustees Of The Leland Stanford Junior University | RNA fixation and detection in clarity-based hydrogel tissue |
| AU2017257624B2 (en) | 2016-04-25 | 2023-05-25 | President And Fellows Of Harvard College | Hybridization chain reaction methods for in situ molecular detection |
| EP3481843B1 (de) | 2016-07-05 | 2022-01-26 | California Institute of Technology | Hybridisierungskettenreaktion mit fraktioniertem initiator |
| IT201600073964A1 (it) * | 2016-07-14 | 2018-01-14 | Ulisse Biomed S R L | Nanointerruttore basato su nucleotidi e metodi per la rilevazione di anticorpi e altri analiti |
| AU2017321492A1 (en) | 2016-08-30 | 2019-03-14 | California Institute Of Technology | Immunohistochemistry via hybridization chain reaction |
| EP3523284A4 (de) | 2016-09-26 | 2021-07-07 | Carnegie Mellon University | Divalente nukleobasenverbindungen und verwendungen davon |
| CN110799576B (zh) | 2017-04-17 | 2023-02-17 | 南加利福尼亚大学 | 生成用于具有多模式标记和信号放大的分析物检测的生物相容的树枝状聚合物的方法 |
| CA3095292A1 (en) | 2018-04-02 | 2019-10-10 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
| CN108624620A (zh) * | 2018-04-02 | 2018-10-09 | 湖南大学 | DNA纳米四分体实现对核酸高效输送及miRNA的超灵敏检测方法 |
| US11414701B2 (en) | 2018-05-24 | 2022-08-16 | The Broad Institute, Inc. | Multimodal readouts for quantifying and sequencing nucleic acids in single cells |
| GB201818742D0 (en) | 2018-11-16 | 2019-01-02 | Cartana Ab | Method for detection of RNA |
| WO2020206170A1 (en) | 2019-04-02 | 2020-10-08 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
| CN110257520B (zh) * | 2019-07-04 | 2020-12-25 | 福州大学 | 一种利用短毛细管高速电泳检测肺癌细胞中miRNA的技术 |
| WO2021034956A2 (en) * | 2019-08-19 | 2021-02-25 | Northwestern University | Controlling the dna hybridization chain reaction |
| GB201919029D0 (en) | 2019-12-20 | 2020-02-05 | Cartana Ab | Method of detecting an analyte |
| GB201919032D0 (en) | 2019-12-20 | 2020-02-05 | Cartana Ab | Method of detecting an analyte |
| EP4284925A1 (de) | 2021-01-26 | 2023-12-06 | California Institute of Technology | Allosterische bedingte guide-rnas zur zellselektiven regulierung von crispr/cas |
| WO2022187366A1 (en) | 2021-03-03 | 2022-09-09 | 10X Genomics, Inc. | Analyte detection in situ using nucleic acid origami |
| US20220380838A1 (en) | 2021-06-01 | 2022-12-01 | 10X Genomics, Inc. | Methods and compositions for analyte detection and probe resolution |
| EP4347880A1 (de) | 2021-06-02 | 2024-04-10 | 10X Genomics, Inc. | Probenanalyse mit asymmetrischen zirkularisierbaren sonden |
| US20230012607A1 (en) | 2021-07-09 | 2023-01-19 | 10X Genomics, Inc. | Methods for detecting analytes using sparse labelling |
| CN117651855A (zh) | 2021-07-13 | 2024-03-05 | 10X基因组学有限公司 | 用于制备具有可控厚度的聚合基质的方法 |
| US20230061542A1 (en) | 2021-08-16 | 2023-03-02 | 10X Genomics, Inc. | Probes comprising a split barcode region and methods of use |
| WO2023059973A1 (en) | 2021-10-08 | 2023-04-13 | University Of Rochester | Nucleic acid hybridization cascade enhanced by droplet evaporation |
| CN114062672B (zh) * | 2021-11-12 | 2023-04-25 | 福州大学 | 一种检测covid-19抗体的血糖生物传感器 |
| WO2023108139A2 (en) | 2021-12-10 | 2023-06-15 | 10X Genomics, Inc. | Multi-resolution in situ decoding |
| CN114231632B (zh) * | 2021-12-20 | 2023-09-22 | 深圳大学 | 一种可刺激性响应的dna水凝胶微针贴片及其制备方法与应用 |
| WO2023129898A2 (en) | 2021-12-27 | 2023-07-06 | 10X Genomics, Inc. | Methods and compositions for rolling circle amplification |
| US20230279475A1 (en) | 2022-01-21 | 2023-09-07 | 10X Genomics, Inc. | Multiple readout signals for analyzing a sample |
| WO2023159240A1 (en) | 2022-02-21 | 2023-08-24 | Kanvas Biosciences, Inc. | Highly multiplexed detection of gene expression with hybridization chain reaction |
| WO2023172915A1 (en) | 2022-03-08 | 2023-09-14 | 10X Genomics, Inc. | In situ code design methods for minimizing optical crowding |
| WO2023192302A1 (en) | 2022-03-29 | 2023-10-05 | 10X Genomics, Inc. | Spectral unmixing combined with decoding for super-multiplexed in situ analysis |
| WO2023192616A1 (en) | 2022-04-01 | 2023-10-05 | 10X Genomics, Inc. | Compositions and methods for targeted masking of autofluorescence |
| WO2023196526A1 (en) | 2022-04-06 | 2023-10-12 | 10X Genomics, Inc. | Methods for multiplex cell analysis |
| WO2023215612A1 (en) | 2022-05-06 | 2023-11-09 | 10X Genomics, Inc. | Analysis of antigen and antigen receptor interactions |
| WO2023220300A1 (en) | 2022-05-11 | 2023-11-16 | 10X Genomics, Inc. | Compositions and methods for in situ sequencing |
| US20240035071A1 (en) | 2022-06-17 | 2024-02-01 | 10X Genomics, Inc. | Catalytic de-crosslinking of samples for in situ analysis |
| WO2024081869A1 (en) | 2022-10-14 | 2024-04-18 | 10X Genomics, Inc. | Methods for analysis of biological samples |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714680B1 (en) | 1984-02-06 | 1995-06-27 | Univ Johns Hopkins | Human stem cells |
| US4965204A (en) | 1984-02-06 | 1990-10-23 | The Johns Hopkins University | Human stem cells and monoclonal antibodies |
| US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| EP0273085A1 (de) | 1986-12-29 | 1988-07-06 | IntraCel Corporation | Verfahren zur Einführung fremder Nukleinsäuren in eukaryotische Zellen |
| US5057410A (en) | 1988-08-05 | 1991-10-15 | Cetus Corporation | Chimeric messenger RNA detection methods |
| US5061620A (en) | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| PL172710B1 (pl) | 1992-07-02 | 1997-11-28 | Hybridon Inc | Samostabilizujacy sie oligonukleotyd PL PL |
| US5677136A (en) | 1994-11-14 | 1997-10-14 | Systemix, Inc. | Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof |
| AU711702B2 (en) | 1995-03-23 | 1999-10-21 | Cambridge University Technical Services Limited | Vectors for gene delivery |
| AU727531B2 (en) | 1995-07-25 | 2000-12-14 | Crucell Holland B.V. | Methods and means for targeted gene delivery |
| US5579793A (en) | 1995-11-15 | 1996-12-03 | Rubbermaid Health Care Products, Inc. | Foldable walker |
| US6361944B1 (en) | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US5928823A (en) * | 1996-12-20 | 1999-07-27 | Fuji Photo Film Co., Ltd. | Method for preparation of waterless lithographic printing plate by electrophotographic process |
| US20020017295A1 (en) | 2000-07-07 | 2002-02-14 | Weers Jeffry G. | Phospholipid-based powders for inhalation |
| AU9692498A (en) | 1997-10-10 | 1999-05-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Complex of biotinylated viral vector and ligand for targeted gene delivery |
| GB9721909D0 (en) | 1997-10-17 | 1997-12-17 | Cantab Pharma Res | Gene delivery vectors and their uses |
| EP1049803A4 (de) * | 1997-12-15 | 2002-08-21 | Nexstar Pharmaceuticals Inc | Gleichmässige erkennung von zielmolekül durch nukleinsäure ligand - beacon ligand interaktion |
| US5989823A (en) | 1998-09-18 | 1999-11-23 | Nexstar Pharmaceuticals, Inc. | Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction |
| US6242246B1 (en) | 1997-12-15 | 2001-06-05 | Somalogic, Inc. | Nucleic acid ligand diagnostic Biochip |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| WO1999047180A1 (en) | 1998-03-20 | 1999-09-23 | Genzyme Corporation | Chimeric adenoviral vectors for targeted gene delivery |
| EP1092047B1 (de) | 1998-07-02 | 2009-08-26 | Gen-Probe Incorporated | Molekulare fackeln |
| DE19843415A1 (de) * | 1998-09-22 | 2000-03-23 | Philips Corp Intellectual Pty | Induktives Bauelement mit einem Stabkern |
| US6899871B2 (en) | 1998-10-01 | 2005-05-31 | University Of Southern California | Gene delivery system and methods of use |
| EP1059357A1 (de) | 1999-06-09 | 2000-12-13 | Universite Pierre Et Marie Curie Paris Vi | Replizierende oder 'semi-replizierende' retrovirale Konstrukte, ihre Herstellung und Verwendungen für den Gentransfer |
| DE19937800B4 (de) | 1999-08-10 | 2005-06-16 | Gea Energietechnik Gmbh | Anlage zur Kondensation von Dampf |
| ATE364722T1 (de) * | 2000-06-02 | 2007-07-15 | Bayer Corp | Verfahren zum nachweis und zur lokalisierung von genen in situ durch hybridisierung einer verzweigten dna |
| US20040223953A1 (en) | 2003-03-17 | 2004-11-11 | Hsiang-Fu Kung | Combined adeno-associated virus and adenovirus cocktail gene delivery system for high efficiency gene expression without eliciting immune response in immuno-competent subjects |
| DE602005023426D1 (de) | 2004-03-25 | 2010-10-21 | California Inst Of Techn | Hybridisierungskettenreaktion |
| US20060234261A1 (en) * | 2005-03-08 | 2006-10-19 | Pierce Niles A | Colorimetric readout of hybridization chain reaction |
| US7727721B2 (en) * | 2005-03-08 | 2010-06-01 | California Institute Of Technology | Hybridization chain reaction amplification for in situ imaging |
| JP2008541698A (ja) | 2005-05-03 | 2008-11-27 | アンサンブル ディスカバリー コーポレイション | 核酸検出のためのターンオーバープローブおよびその使用 |
| WO2007044727A2 (en) * | 2005-10-07 | 2007-04-19 | California Institute Of Technology | Pkr activation via hybridization chain reaction |
| EP2155770B1 (de) * | 2007-05-16 | 2013-10-16 | California Institute of Technology | Vielseitiges nukleinsäure-haarnadel-motiv zur programmierung biomolekularer selbstanordnungspfade |
-
2005
- 2005-03-22 DE DE602005023426T patent/DE602005023426D1/de active Active
- 2005-03-22 US US11/087,937 patent/US7632641B2/en active Active
- 2005-03-22 WO PCT/US2005/009471 patent/WO2005098049A2/en active Application Filing
- 2005-03-22 EP EP05730392A patent/EP1730161B1/de active Active
- 2005-03-22 AT AT05730392T patent/ATE480550T1/de not_active IP Right Cessation
-
2009
- 2009-11-03 US US12/611,875 patent/US8105778B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20050260635A1 (en) | 2005-11-24 |
| WO2005098049A2 (en) | 2005-10-20 |
| EP1730161B1 (de) | 2010-09-08 |
| EP1730161A2 (de) | 2006-12-13 |
| US7632641B2 (en) | 2009-12-15 |
| WO2005098049A3 (en) | 2006-05-11 |
| EP1730161A4 (de) | 2008-05-21 |
| US8105778B2 (en) | 2012-01-31 |
| ATE480550T1 (de) | 2010-09-15 |
| US20100047926A1 (en) | 2010-02-25 |
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