MXPA04002967A - Hidrogel biocompatible polifuncional y metodo para la produccion del mismo. - Google Patents
Hidrogel biocompatible polifuncional y metodo para la produccion del mismo.Info
- Publication number
- MXPA04002967A MXPA04002967A MXPA04002967A MXPA04002967A MXPA04002967A MX PA04002967 A MXPA04002967 A MX PA04002967A MX PA04002967 A MXPA04002967 A MX PA04002967A MX PA04002967 A MXPA04002967 A MX PA04002967A MX PA04002967 A MXPA04002967 A MX PA04002967A
- Authority
- MX
- Mexico
- Prior art keywords
- mass
- acrylamide
- carried out
- biocompatible hydrogel
- production
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
- C08K5/0025—Crosslinking or vulcanising agents; including accelerators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/02—Elements
- C08K3/08—Metals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S524/00—Synthetic resins or natural rubbers -- part of the class 520 series
- Y10S524/916—Hydrogel compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Colloid Chemistry (AREA)
Abstract
Se describe un hidrogel biocompatible polifuncional y proceso para la preparacion del mismo que contiene de 1.3 a 5 % en masa de acrilaminda, de 0.004 - 0,975 % de agentes de entrecruzamiento de N,N`- metilen-bis-acrilaminda, 0.004 - 5.1 % de N,N`-metilen-bis-acrilaminda, 0.002 - 0.45 de poviargolum, y el resto hasta 100 de agua. El hidrogel es producido por la copolimerizacion de acrilaminada con agentes de entrecruzamiento en un medio acuoso en la presencia de un peroxido iniciador de polimerizacion, en la incubacion del compuesto de reaccion en dos etapas, la primera de la cual es conducida a una temperatura de 20 - 90degree c y la segunda a una temperatura de 17?? a 130degree c por no mas de dos horas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU2001/000392 WO2003026711A1 (fr) | 2001-09-28 | 2001-09-28 | Hydrogel biocompatible polyfonctionnel et procede de production associe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04002967A true MXPA04002967A (es) | 2004-07-15 |
Family
ID=20129652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04002967A MXPA04002967A (es) | 2001-09-28 | 2001-09-28 | Hidrogel biocompatible polifuncional y metodo para la produccion del mismo. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7294348B2 (es) |
| EP (1) | EP1438976B1 (es) |
| CN (1) | CN1257752C (es) |
| AT (1) | ATE381356T1 (es) |
| BR (1) | BR0117137B1 (es) |
| CA (1) | CA2461821C (es) |
| DE (1) | DE60132025T2 (es) |
| DK (1) | DK1438976T3 (es) |
| ES (1) | ES2298195T3 (es) |
| MX (1) | MXPA04002967A (es) |
| RU (1) | RU2205034C1 (es) |
| WO (1) | WO2003026711A1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0303798D0 (en) * | 2003-02-19 | 2003-03-26 | Bioartem Ltd | Gel |
| GB0327310D0 (en) * | 2003-11-24 | 2003-12-24 | Oztech Pty Ltd | Pressure impulse mitigation |
| DE102007040370B4 (de) * | 2007-08-20 | 2011-06-16 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Kollagenhaltiger Zellträger |
| DE102009005534B3 (de) * | 2008-12-18 | 2010-04-01 | Heraeus Medical Gmbh | Sporozide Zusammensetzungen und deren Verwendung |
| WO2010074958A1 (en) | 2008-12-22 | 2010-07-01 | The Trustees Of The University Of Pennsylvania | Hydrolytically degradable polysaccharide hydrogels |
| US9486404B2 (en) * | 2011-03-28 | 2016-11-08 | The Trustees Of The University Of Pennsylvania | Infarction treatment compositions and methods |
| RU2493173C1 (ru) * | 2012-03-22 | 2013-09-20 | Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт нефтехимического синтеза им. А.В. Топчиева Российской академии наук (ИНХС РАН) | Способ получения полиакриламидного гидрогеля |
| RU2499003C1 (ru) * | 2012-03-22 | 2013-11-20 | Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт нефтехимического синтеза им. А.В. Топчиева Российской академии наук (ИНХС РАН) | Способ получения полиакриламидного гидрогеля |
| EP4163617A1 (en) * | 2012-08-09 | 2023-04-12 | The Board of Trustees of the Leland Stanford Junior University | Methods and compositions for preparing biological specimens for microscopic analysis |
| RU2545806C1 (ru) | 2013-12-26 | 2015-04-10 | Международная коммерческая компания "НЬЮКРОСС ВЕНТУРЕС ЛТД" | Материал медицинского назначения "матрексин" на основе полиакриламидного гидрогеля и способ его получения (варианты) |
| WO2015146221A1 (ja) * | 2014-03-24 | 2015-10-01 | 富士フイルム株式会社 | 生体臓器模型用水性ゲル組成物および生体臓器模型 |
| WO2015184124A1 (en) | 2014-05-30 | 2015-12-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging large intact tissue samples |
| AU2016364917A1 (en) * | 2015-12-02 | 2018-06-21 | Clearlight Diagnostics Llc | Methods for preparing and analyzing tumor tissue samples for detection and monitoring of cancers |
| WO2017139501A1 (en) | 2016-02-10 | 2017-08-17 | The Board Of Trustees Of The Leland Stanford Junior University | Rna fixation and detection in clarity-based hydrogel tissue |
| RU2633490C1 (ru) * | 2016-11-23 | 2017-10-12 | Общество с ограниченной ответственностью "Медицина 3Д" | Материал для замещения дефектов мягких тканей |
| PL241064B1 (pl) | 2018-10-01 | 2022-08-01 | Dolniak Blazej | Sposób wytwarzania lepko-sprężystego żelu uzupełniającego maź stawową i lepko-sprężysty żel uzupełniający maź stawową |
| WO2023239695A1 (en) * | 2022-06-06 | 2023-12-14 | Phrixionls, Llc | Prophylaxis and treatment of degraded cartilage |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2114578B (en) | 1979-11-06 | 1984-06-27 | Ki Med I | Polyacrylamide gel for medical and biological application and method of its preparation |
| UA10911C2 (uk) | 1994-08-10 | 1996-12-25 | Мале Впроваджувальне Підприємство "Іhтерфалл" | Біосумісhий гідрогель |
| RU2088234C1 (ru) | 1994-11-25 | 1997-08-27 | Институт высокомолекулярных соединений РАН | Водорастворимая бактерицидная композиция и способ ее получения |
| US5941909A (en) * | 1995-02-14 | 1999-08-24 | Mentor Corporation | Filling material for soft tissue implant prostheses and implants made therewith |
| US5658329A (en) * | 1995-02-14 | 1997-08-19 | Mentor Corporation | Filling material for soft tissue implant prostheses and implants made therewith |
| RU2127129C1 (ru) * | 1996-05-28 | 1999-03-10 | Владислав Викторович Лопатин | Способ получения гелеобразного материала для пластики мягких тканей |
| RU2127095C1 (ru) * | 1996-05-28 | 1999-03-10 | Владислав Викторович Лопатин | Эндопротез молочной железы |
| RU2146127C1 (ru) * | 1996-08-07 | 2000-03-10 | Закрытое акционерное общество "Агрофарм-Питер-Сиб" | Мазь для лечения инфицированных ран |
| BG102375A (en) * | 1997-08-26 | 1999-11-30 | Пегас Оод | Inoculation biocompatible hydrophilic gel, method for its preparation and application |
| AU2001900A (en) * | 1999-12-29 | 2001-07-16 | Progen S.R.L. | Biocompatible hydrogel and method of its production |
-
2001
- 2001-09-28 US US10/490,969 patent/US7294348B2/en not_active Expired - Lifetime
- 2001-09-28 AT AT01274505T patent/ATE381356T1/de active
- 2001-09-28 DK DK01274505T patent/DK1438976T3/da active
- 2001-09-28 WO PCT/RU2001/000392 patent/WO2003026711A1/ru active IP Right Grant
- 2001-09-28 CN CNB018236650A patent/CN1257752C/zh not_active Expired - Fee Related
- 2001-09-28 EP EP01274505A patent/EP1438976B1/en not_active Expired - Lifetime
- 2001-09-28 CA CA2461821A patent/CA2461821C/en not_active Expired - Lifetime
- 2001-09-28 DE DE60132025T patent/DE60132025T2/de not_active Expired - Lifetime
- 2001-09-28 MX MXPA04002967A patent/MXPA04002967A/es active IP Right Grant
- 2001-09-28 RU RU2002102867/14A patent/RU2205034C1/ru not_active IP Right Cessation
- 2001-09-28 ES ES01274505T patent/ES2298195T3/es not_active Expired - Lifetime
- 2001-09-28 BR BRPI0117137-2A patent/BR0117137B1/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1257752C (zh) | 2006-05-31 |
| ATE381356T1 (de) | 2008-01-15 |
| RU2205034C1 (ru) | 2003-05-27 |
| DE60132025D1 (de) | 2008-01-31 |
| CA2461821C (en) | 2011-03-15 |
| ES2298195T3 (es) | 2008-05-16 |
| BR0117137A (pt) | 2004-10-13 |
| US7294348B2 (en) | 2007-11-13 |
| DE60132025T2 (de) | 2008-12-04 |
| DK1438976T3 (da) | 2008-04-28 |
| CN1549732A (zh) | 2004-11-24 |
| US20040241241A1 (en) | 2004-12-02 |
| EP1438976A4 (en) | 2007-04-18 |
| EP1438976A1 (en) | 2004-07-21 |
| CA2461821A1 (en) | 2004-04-03 |
| WO2003026711A1 (fr) | 2003-04-03 |
| EP1438976B1 (en) | 2007-12-19 |
| BR0117137B1 (pt) | 2014-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |