IL88517A - Water-soluble camptocin analogues, their preparation, pharmaceutical preparations containing the same intermediates and their preparation - Google Patents

Water-soluble camptocin analogues, their preparation, pharmaceutical preparations containing the same intermediates and their preparation

Info

Publication number
IL88517A
IL88517A IL8851788A IL8851788A IL88517A IL 88517 A IL88517 A IL 88517A IL 8851788 A IL8851788 A IL 8851788A IL 8851788 A IL8851788 A IL 8851788A IL 88517 A IL88517 A IL 88517A
Authority
IL
Israel
Prior art keywords
compound
hydroxy
hydrogen
formyl
formula
Prior art date
Application number
IL8851788A
Other languages
English (en)
Hebrew (he)
Other versions
IL88517A0 (en
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of IL88517A0 publication Critical patent/IL88517A0/xx
Publication of IL88517A publication Critical patent/IL88517A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
IL8851788A 1987-12-01 1988-11-28 Water-soluble camptocin analogues, their preparation, pharmaceutical preparations containing the same intermediates and their preparation IL88517A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12714887A 1987-12-01 1987-12-01

Publications (2)

Publication Number Publication Date
IL88517A0 IL88517A0 (en) 1989-06-30
IL88517A true IL88517A (en) 1994-10-07

Family

ID=22428545

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8851788A IL88517A (en) 1987-12-01 1988-11-28 Water-soluble camptocin analogues, their preparation, pharmaceutical preparations containing the same intermediates and their preparation

Country Status (25)

Country Link
US (1) US5004758A (fi)
EP (1) EP0321122B1 (fi)
JP (1) JPH0633268B2 (fi)
KR (1) KR930009357B1 (fi)
CN (3) CN1027265C (fi)
AT (1) ATE143368T1 (fi)
AU (1) AU612735B2 (fi)
CA (1) CA1308102C (fi)
CY (1) CY2017A (fi)
DE (2) DE19775017I2 (fi)
DK (1) DK173034B1 (fi)
ES (1) ES2094721T3 (fi)
FI (1) FI89923C (fi)
GR (1) GR3021990T3 (fi)
HK (1) HK81097A (fi)
IE (1) IE74873B1 (fi)
IL (1) IL88517A (fi)
LU (2) LU90026I2 (fi)
MX (1) MX9203744A (fi)
NL (1) NL970017I2 (fi)
NO (2) NO170487C (fi)
NZ (1) NZ227124A (fi)
PT (1) PT89111B (fi)
SG (1) SG66254A1 (fi)
ZA (1) ZA888938B (fi)

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US4775759A (en) * 1984-11-27 1988-10-04 The United States Of America As Represented By The Department Of Health And Human Services Synthesis and utilization of 17-methyl and 17-cyclopropylmethyl-3,14-dihydroxy-4,5α-epoxy 6β-fluoromorphinans (foxy and cyclofoxy) as (18F)-labeled opioid ligands for position emission transaxial tomography (PETT)
US4820816A (en) * 1985-08-02 1989-04-11 President And Fellows Of Harvard College 3-trifuoromethylsulfonyloxy-substituted 1-carbacephalosporins as intermediates for antibiotics
JPH0615546B2 (ja) * 1986-02-24 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体
US4894456A (en) * 1987-03-31 1990-01-16 Research Triangle Institute Synthesis of camptothecin and analogs thereof
JP3431931B2 (ja) * 1992-07-16 2003-07-28 旭電化工業株式会社 銅及び銅合金の表面処理方法

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US5004758A (en) 1991-04-02
AU612735B2 (en) 1991-07-18
EP0321122A3 (en) 1990-12-27
SG66254A1 (en) 1999-07-20
DE3855575T2 (de) 1997-03-20
ZA888938B (en) 1990-03-28
NO1998003I1 (no) 1998-01-15
FI885569A (fi) 1989-06-02
FI89923B (fi) 1993-08-31
IE74873B1 (en) 1997-08-13
DK173034B1 (da) 1999-11-29
CN1035380C (zh) 1997-07-09
NO170487B (no) 1992-07-13
NO885352L (no) 1989-06-02
MX9203744A (es) 1992-09-01
KR930009357B1 (ko) 1993-09-28
JPH0633268B2 (ja) 1994-05-02
NO885352D0 (no) 1988-11-30
LU90053I2 (fr) 1997-07-01
CY2017A (en) 1998-02-20
NL970017I2 (nl) 1997-09-01
CA1308102C (en) 1992-09-29
PT89111B (pt) 1994-01-31
FI885569A0 (fi) 1988-11-30
CN1034724A (zh) 1989-08-16
JPH01186893A (ja) 1989-07-26
FI89923C (fi) 1993-12-10
DK663688D0 (da) 1988-11-28
CN1083817A (zh) 1994-03-16
CN1087637A (zh) 1994-06-08
KR890009934A (ko) 1989-08-05
NZ227124A (en) 1991-12-23
DE19775017I2 (de) 2002-11-07
NO170487C (no) 1992-10-21
DE3855575D1 (de) 1996-10-31
DK663688A (da) 1989-06-02
IE883576L (en) 1989-06-01
GR3021990T3 (en) 1997-03-31
PT89111A (pt) 1989-12-29
CN1037574C (zh) 1998-03-04
IL88517A0 (en) 1989-06-30
EP0321122A2 (en) 1989-06-21
NL970017I1 (nl) 1997-06-02
HK81097A (en) 1997-06-20
ATE143368T1 (de) 1996-10-15
ES2094721T3 (es) 1997-02-01
EP0321122B1 (en) 1996-09-25
AU2639488A (en) 1989-06-01
CN1027265C (zh) 1995-01-04
LU90026I2 (fr) 1997-04-22

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