IL73159A - Carboxyalkenamido-cephalosporins,processes for the preparation thereof and methods for the use thereof - Google Patents
Carboxyalkenamido-cephalosporins,processes for the preparation thereof and methods for the use thereofInfo
- Publication number
- IL73159A IL73159A IL73159A IL7315984A IL73159A IL 73159 A IL73159 A IL 73159A IL 73159 A IL73159 A IL 73159A IL 7315984 A IL7315984 A IL 7315984A IL 73159 A IL73159 A IL 73159A
- Authority
- IL
- Israel
- Prior art keywords
- carboxyalkenamido
- cephalosporins
- processes
- preparation
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 229940124587 cephalosporin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL84653A IL84653A (en) | 1983-10-04 | 1984-10-04 | Amino-alpha-carboxyethylidenethiazoleacetic acid derivatives and processes for the preparation thereof |
IL84653A IL84653A0 (en) | 1983-10-04 | 1987-11-27 | Carboxybutenoic acids and processes for the preparation thereof |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58186601A JPS6078987A (ja) | 1983-10-04 | 1983-10-04 | アクリルアミドセフアロスポリン類 |
JP59018563A JPS60163884A (ja) | 1984-02-03 | 1984-02-03 | カルボキシアルケンアミドセフアロスポリン |
JP59100890A JPH0780892B2 (ja) | 1984-05-18 | 1984-05-18 | カルボキシアルケンアミドセフアロスポリン |
Publications (2)
Publication Number | Publication Date |
---|---|
IL73159A0 IL73159A0 (en) | 1985-01-31 |
IL73159A true IL73159A (en) | 1990-08-31 |
Family
ID=27282263
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL84653A IL84653A (en) | 1983-10-04 | 1984-10-04 | Amino-alpha-carboxyethylidenethiazoleacetic acid derivatives and processes for the preparation thereof |
IL73159A IL73159A (en) | 1983-10-04 | 1984-10-04 | Carboxyalkenamido-cephalosporins,processes for the preparation thereof and methods for the use thereof |
IL84653A IL84653A0 (en) | 1983-10-04 | 1987-11-27 | Carboxybutenoic acids and processes for the preparation thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL84653A IL84653A (en) | 1983-10-04 | 1984-10-04 | Amino-alpha-carboxyethylidenethiazoleacetic acid derivatives and processes for the preparation thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL84653A IL84653A0 (en) | 1983-10-04 | 1987-11-27 | Carboxybutenoic acids and processes for the preparation thereof |
Country Status (22)
Country | Link |
---|---|
US (3) | US4634697A (de) |
EP (1) | EP0136721B1 (de) |
KR (2) | KR880002376B1 (de) |
AR (1) | AR242392A1 (de) |
AT (1) | ATE99311T1 (de) |
AU (2) | AU575854B2 (de) |
CA (2) | CA1238910A (de) |
DE (2) | DE3486259T2 (de) |
DK (1) | DK171043B1 (de) |
ES (3) | ES8604602A1 (de) |
FI (1) | FI82057C (de) |
GB (3) | GB2154580B (de) |
GR (1) | GR80544B (de) |
HU (1) | HU193298B (de) |
IE (1) | IE57744B1 (de) |
IL (3) | IL84653A (de) |
MX (1) | MX174328B (de) |
NL (1) | NL940013I2 (de) |
NO (2) | NO173238C (de) |
NZ (2) | NZ218741A (de) |
PH (2) | PH20223A (de) |
PT (1) | PT79287A (de) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU575854B2 (en) * | 1983-10-04 | 1988-08-11 | Shionogi & Co., Ltd. | 7beta-(carboxyalkenamido) cephalosporins |
JP2501785B2 (ja) * | 1984-07-09 | 1996-05-29 | 明治製菓株式会社 | 新規セフアロスポリン系化合物 |
JPS6124580A (ja) * | 1984-07-12 | 1986-02-03 | Shionogi & Co Ltd | アミノチアゾリルグルタル酸誘導体の製造方法 |
JPS6153272A (ja) * | 1984-08-24 | 1986-03-17 | Shionogi & Co Ltd | グルタル酸誘導体の製法 |
AU580855B2 (en) * | 1985-03-29 | 1989-02-02 | Shionogi & Co., Ltd. | Alkeneamidocephalosporin esters |
EP0202046B1 (de) | 1985-04-30 | 1991-01-30 | Eli Lilly And Company | 7-Substituierte bicyclische Pyrazolidinone |
US4731362A (en) * | 1985-08-05 | 1988-03-15 | Shionogi & Co., Ltd. | Alkylcarbamoyloxymethylcephem compounds |
DE3745094B4 (de) * | 1986-07-02 | 2004-12-30 | Shionogi & Co., Ltd. | Ein kristallines Hydrat der 7ß-[(Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carbonsäure enthaltende Hartgelatinekapsel-Zusammensetzung |
NZ220764A (en) * | 1986-07-02 | 1989-09-27 | Shionogi & Co | Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions |
US5017380A (en) * | 1986-07-02 | 1991-05-21 | Shionogi & Co., Ltd. | Gelatin hard capsule containing crystalline hydrate of oral cephalosporin |
AT396652B (de) * | 1986-07-02 | 1993-11-25 | Shionogi & Co | Verfahren zur herstellung von hartgelatinekapsel-zusammensetzungen |
US5147871A (en) * | 1986-07-03 | 1992-09-15 | Hoffmann La-Roche, Inc. | Anti-bacterial cephalosporin compounds |
US5242913A (en) * | 1987-03-11 | 1993-09-07 | Pfizer Inc. | Substituted 3-cephem compounds as antibacterial agents |
US5079242A (en) * | 1987-03-11 | 1992-01-07 | Pfizer Inc. | Substituted 3-cephem compounds as antibacterial agents |
US4820832A (en) * | 1988-03-23 | 1989-04-11 | Eli Lilly And Company | Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins |
CS273349B2 (en) * | 1988-03-31 | 1991-03-12 | Hoffmann La Roche | Method of cephalosporin's new derivatives production |
US5336768A (en) * | 1988-05-24 | 1994-08-09 | Hoffmann-La Roche Inc. | Antibacterial cephalosporin compounds |
US5245027A (en) * | 1989-11-21 | 1993-09-14 | Bristol-Myers Squibb Company | 3-fluorosulfonyloxyceph-3-em compounds |
US5612048A (en) * | 1994-11-22 | 1997-03-18 | Amvac Chemical Corporation | Stabilized moisture-sensitive pesticide composition and method of making |
US5571910A (en) * | 1994-12-09 | 1996-11-05 | Schering Corporation | Process for the preparation of intermediates useful in the synthesis of cephalosporins |
JPH101482A (ja) * | 1996-06-13 | 1998-01-06 | Otsuka Chem Co Ltd | 3−ノルセフェム化合物の製造法 |
US6544555B2 (en) * | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US6565882B2 (en) * | 2000-02-24 | 2003-05-20 | Advancis Pharmaceutical Corp | Antibiotic composition with inhibitor |
US6541014B2 (en) * | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
US20020068078A1 (en) * | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
US20020197314A1 (en) * | 2001-02-23 | 2002-12-26 | Rudnic Edward M. | Anti-fungal composition |
US8225458B1 (en) | 2001-07-13 | 2012-07-24 | Hoffberg Steven M | Intelligent door restraint |
IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
US20050152852A1 (en) * | 2002-05-27 | 2005-07-14 | Morinaga & Co., Ltd. | Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria |
AU2004258944B2 (en) * | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
CA2533292C (en) * | 2003-07-21 | 2013-12-31 | Advancis Pharmaceutical Corporation | Antibiotic product, use and formulation thereof |
AU2004258949B2 (en) * | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
JP2007502296A (ja) * | 2003-08-11 | 2007-02-08 | アドバンシス ファーマスーティカル コーポレイション | ロバストペレット |
US8062672B2 (en) * | 2003-08-12 | 2011-11-22 | Shionogi Inc. | Antibiotic product, use and formulation thereof |
WO2005023184A2 (en) * | 2003-08-29 | 2005-03-17 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
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EP1701705A4 (de) * | 2003-12-24 | 2007-08-08 | Advancis Pharmaceutical Corp | Verbesserte absorption von dosierformen mit modifizierter freisetzung |
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US20110104109A1 (en) * | 2005-07-13 | 2011-05-05 | Frank Bennett | Tetracyclic indole derivatives and their use for treating or preventing viral infections |
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US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
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MX2010002317A (es) | 2007-08-29 | 2010-03-22 | Schering Corp | Derivados de indol sustituidos y metodos para su utilizacion. |
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CA2734489C (en) | 2008-08-20 | 2016-11-08 | Southern Research Institute | Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
AR072940A1 (es) | 2008-08-20 | 2010-09-29 | Schering Corp | Derivados de piridina y pirimidina sustituidos con etinilo y su uso en el tratamiento de infecciones virales |
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WO2013151518A1 (en) | 2012-04-04 | 2013-10-10 | Mahmut Bilgic | Capsule formulations comprising ceftibuten |
EP2815743A1 (de) | 2013-06-21 | 2014-12-24 | Sanovel Ilac Sanayi ve Ticaret A.S. | Formulierungen mit Ceftibuten |
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Family Cites Families (12)
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---|---|---|---|---|
GB149039A (en) * | 1919-04-30 | 1920-07-30 | Lawrence Ennis | Improvements in or relating to steel framed cottages |
GB966131A (en) * | 1959-04-07 | 1964-08-06 | Union Carbide Corp | Process for the preparation of organic compounds |
US3994888A (en) * | 1973-06-18 | 1976-11-30 | Eli Lilly And Company | Cephalosporin cleavage process |
GB1497039A (en) * | 1973-12-05 | 1978-01-05 | Glaxo Lab Ltd | Penicillins and cephalosporins |
US4263212A (en) * | 1979-02-28 | 1981-04-21 | Rikagaku Kenkyusho | Process for preparation of substituted olefins |
GB2076801A (en) * | 1980-04-14 | 1981-12-09 | Erba Farmitalia | alpha , beta -Disubstituted Acrylamido Cephalosporins |
DE3037997A1 (de) * | 1980-10-08 | 1982-05-13 | Bayer Ag | (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
DE3145727A1 (de) * | 1981-11-19 | 1983-05-26 | Bayer Ag, 5090 Leverkusen | Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen |
CA1201431A (en) * | 1981-12-17 | 1986-03-04 | Daiei Tunemoto | .beta.-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF |
DE3224866A1 (de) * | 1982-07-02 | 1984-01-05 | Bayer Ag, 5090 Leverkusen | Ss-lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
DE3300593A1 (de) * | 1983-01-11 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Neue cephalosporine und verfahren zu ihrer herstellung |
AU575854B2 (en) * | 1983-10-04 | 1988-08-11 | Shionogi & Co., Ltd. | 7beta-(carboxyalkenamido) cephalosporins |
-
1984
- 1984-09-19 AU AU33300/84A patent/AU575854B2/en not_active Expired
- 1984-09-21 NZ NZ218741A patent/NZ218741A/xx unknown
- 1984-09-21 NZ NZ209634A patent/NZ209634A/xx unknown
- 1984-09-25 PH PH31265A patent/PH20223A/en unknown
- 1984-09-27 CA CA000464215A patent/CA1238910A/en not_active Expired
- 1984-10-01 PT PT79287A patent/PT79287A/pt unknown
- 1984-10-02 NO NO843956A patent/NO173238C/no not_active IP Right Cessation
- 1984-10-02 FI FI843871A patent/FI82057C/fi not_active IP Right Cessation
- 1984-10-03 DK DK474584A patent/DK171043B1/da not_active IP Right Cessation
- 1984-10-03 GB GB08424923A patent/GB2154580B/en not_active Expired
- 1984-10-03 IE IE2524/84A patent/IE57744B1/en not_active IP Right Cessation
- 1984-10-03 HU HU843743A patent/HU193298B/hu unknown
- 1984-10-03 GR GR80544A patent/GR80544B/el unknown
- 1984-10-03 MX MX013280A patent/MX174328B/es unknown
- 1984-10-04 AR AR84298181A patent/AR242392A1/es active
- 1984-10-04 EP EP84111916A patent/EP0136721B1/de not_active Expired - Lifetime
- 1984-10-04 AT AT84111916T patent/ATE99311T1/de active
- 1984-10-04 IL IL84653A patent/IL84653A/xx not_active IP Right Cessation
- 1984-10-04 KR KR1019840006134A patent/KR880002376B1/ko not_active IP Right Cessation
- 1984-10-04 DE DE3486259T patent/DE3486259T2/de not_active Expired - Lifetime
- 1984-10-04 DE DE198484111916T patent/DE136721T1/de active Pending
- 1984-10-04 IL IL73159A patent/IL73159A/xx not_active IP Right Cessation
- 1984-10-04 ES ES536502A patent/ES8604602A1/es not_active Expired
-
1985
- 1985-03-12 US US06/711,017 patent/US4634697A/en not_active Expired - Lifetime
- 1985-08-29 ES ES547300A patent/ES8700222A1/es not_active Expired
- 1985-08-29 ES ES547301A patent/ES8605278A1/es not_active Expired
- 1985-09-27 NO NO853806A patent/NO176567C/no not_active IP Right Cessation
-
1986
- 1986-02-20 US US06/831,435 patent/US4748170A/en not_active Expired - Lifetime
- 1986-05-27 PH PH33818A patent/PH21766A/en unknown
-
1987
- 1987-01-06 GB GB08700123A patent/GB2190914B/en not_active Expired
- 1987-03-04 CA CA000531176A patent/CA1272713A/en not_active Expired - Lifetime
- 1987-11-13 GB GB08726623A patent/GB2198727B/en not_active Expired
- 1987-11-27 IL IL84653A patent/IL84653A0/xx unknown
- 1987-12-09 US US07/132,882 patent/US4912224A/en not_active Expired - Lifetime
-
1988
- 1988-05-16 AU AU16194/88A patent/AU601842B2/en not_active Expired
- 1988-09-21 KR KR1019880012223A patent/KR880002684B1/ko not_active IP Right Cessation
-
1994
- 1994-07-04 NL NL940013C patent/NL940013I2/nl unknown
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