DE3486259D1 - Carboxyalkenamidocephalosporine. - Google Patents

Carboxyalkenamidocephalosporine.

Info

Publication number
DE3486259D1
DE3486259D1 DE84111916T DE3486259T DE3486259D1 DE 3486259 D1 DE3486259 D1 DE 3486259D1 DE 84111916 T DE84111916 T DE 84111916T DE 3486259 T DE3486259 T DE 3486259T DE 3486259 D1 DE3486259 D1 DE 3486259D1
Authority
DE
Germany
Prior art keywords
carboxyalkenamidocephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE84111916T
Other languages
English (en)
Other versions
DE3486259T2 (de
Inventor
Yoshio Hamashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58186601A external-priority patent/JPS6078987A/ja
Priority claimed from JP59018563A external-priority patent/JPS60163884A/ja
Priority claimed from JP59100890A external-priority patent/JPH0780892B2/ja
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE3486259D1 publication Critical patent/DE3486259D1/de
Publication of DE3486259T2 publication Critical patent/DE3486259T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
DE3486259T 1983-10-04 1984-10-04 Carboxyalkenamidocephalosporine. Expired - Lifetime DE3486259T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP58186601A JPS6078987A (ja) 1983-10-04 1983-10-04 アクリルアミドセフアロスポリン類
JP59018563A JPS60163884A (ja) 1984-02-03 1984-02-03 カルボキシアルケンアミドセフアロスポリン
JP59100890A JPH0780892B2 (ja) 1984-05-18 1984-05-18 カルボキシアルケンアミドセフアロスポリン

Publications (2)

Publication Number Publication Date
DE3486259D1 true DE3486259D1 (de) 1994-02-10
DE3486259T2 DE3486259T2 (de) 1994-07-21

Family

ID=27282263

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3486259T Expired - Lifetime DE3486259T2 (de) 1983-10-04 1984-10-04 Carboxyalkenamidocephalosporine.
DE198484111916T Pending DE136721T1 (de) 1983-10-04 1984-10-04 Carboxyalkenamidocephalosporine.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198484111916T Pending DE136721T1 (de) 1983-10-04 1984-10-04 Carboxyalkenamidocephalosporine.

Country Status (22)

Country Link
US (3) US4634697A (de)
EP (1) EP0136721B1 (de)
KR (2) KR880002376B1 (de)
AR (1) AR242392A1 (de)
AT (1) ATE99311T1 (de)
AU (2) AU575854B2 (de)
CA (2) CA1238910A (de)
DE (2) DE3486259T2 (de)
DK (1) DK171043B1 (de)
ES (3) ES8604602A1 (de)
FI (1) FI82057C (de)
GB (3) GB2154580B (de)
GR (1) GR80544B (de)
HU (1) HU193298B (de)
IE (1) IE57744B1 (de)
IL (3) IL84653A (de)
MX (1) MX174328B (de)
NL (1) NL940013I2 (de)
NO (2) NO173238C (de)
NZ (2) NZ218741A (de)
PH (2) PH20223A (de)
PT (1) PT79287A (de)

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JPS6153272A (ja) * 1984-08-24 1986-03-17 Shionogi & Co Ltd グルタル酸誘導体の製法
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters
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US4731362A (en) * 1985-08-05 1988-03-15 Shionogi & Co., Ltd. Alkylcarbamoyloxymethylcephem compounds
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DE3745094B4 (de) * 1986-07-02 2004-12-30 Shionogi & Co., Ltd. Ein kristallines Hydrat der 7ß-[(Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carbonsäure enthaltende Hartgelatinekapsel-Zusammensetzung
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
US5079242A (en) * 1987-03-11 1992-01-07 Pfizer Inc. Substituted 3-cephem compounds as antibacterial agents
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US4820832A (en) * 1988-03-23 1989-04-11 Eli Lilly And Company Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins
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Also Published As

Publication number Publication date
ES547300A0 (es) 1986-11-16
ES547301A0 (es) 1986-03-16
NO173238C (no) 1993-11-17
DE136721T1 (de) 1985-08-29
EP0136721B1 (de) 1993-12-29
AR242392A1 (es) 1993-03-31
AU575854B2 (en) 1988-08-11
CA1238910A (en) 1988-07-05
DK171043B1 (da) 1996-04-29
NZ218741A (en) 1988-07-28
DK474584A (da) 1985-04-05
DE3486259T2 (de) 1994-07-21
GB2154580B (en) 1988-08-17
NO176567C (no) 1995-04-26
GB8726623D0 (en) 1987-12-16
GB2190914A (en) 1987-12-02
ES8605278A1 (es) 1986-03-16
US4748170A (en) 1988-05-31
PT79287A (en) 1984-11-01
KR850002989A (ko) 1985-05-28
FI82057C (fi) 1991-01-10
MX174328B (es) 1994-05-09
FI843871L (fi) 1985-04-05
DK474584D0 (da) 1984-10-03
IE842524L (en) 1985-04-04
ES8604602A1 (es) 1986-02-01
AU601842B2 (en) 1990-09-20
GB8424923D0 (en) 1984-11-07
NO853806L (no) 1985-04-09
AU3330084A (en) 1985-05-09
EP0136721A2 (de) 1985-04-10
ES536502A0 (es) 1986-02-01
NO173238B (no) 1993-08-09
CA1272713A (en) 1990-08-14
HU193298B (en) 1987-09-28
NO843956L (no) 1985-04-09
NZ209634A (en) 1988-07-28
FI843871A0 (fi) 1984-10-02
GB2198727B (en) 1988-11-16
IL73159A (en) 1990-08-31
ATE99311T1 (de) 1994-01-15
IL73159A0 (en) 1985-01-31
FI82057B (fi) 1990-09-28
GB8700123D0 (en) 1987-02-11
IL84653A (en) 1990-08-31
EP0136721A3 (en) 1986-01-22
ES8700222A1 (es) 1986-11-16
NL940013I1 (nl) 1994-08-16
NO176567B (no) 1995-01-16
PH20223A (en) 1986-10-23
GB2154580A (en) 1985-09-11
KR880002684B1 (ko) 1988-12-20
IL84653A0 (en) 1988-04-29
US4912224A (en) 1990-03-27
US4634697A (en) 1987-01-06
GR80544B (en) 1985-02-05
AU1619488A (en) 1988-08-11
GB2190914B (en) 1988-08-17
NL940013I2 (nl) 1999-06-01
IE57744B1 (en) 1993-03-24
GB2198727A (en) 1988-06-22
CA1272713C (de) 1990-08-14
HUT36129A (en) 1985-08-28
KR880002376B1 (ko) 1988-11-03
PH21766A (en) 1988-02-18

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