ES547300A0 - Nuevo procedimiento para la fabricacion de acido 7-beta- (carboxialquenoilamino)-3-cefem-4-carboxilico - Google Patents

Nuevo procedimiento para la fabricacion de acido 7-beta- (carboxialquenoilamino)-3-cefem-4-carboxilico

Info

Publication number
ES547300A0
ES547300A0 ES547300A ES547300A ES547300A0 ES 547300 A0 ES547300 A0 ES 547300A0 ES 547300 A ES547300 A ES 547300A ES 547300 A ES547300 A ES 547300A ES 547300 A0 ES547300 A0 ES 547300A0
Authority
ES
Spain
Prior art keywords
carboxialquenoilamino
carboxilico
cefem
beta
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES547300A
Other languages
English (en)
Other versions
ES8700222A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58186601A external-priority patent/JPS6078987A/ja
Priority claimed from JP59018563A external-priority patent/JPS60163884A/ja
Priority claimed from JP59100890A external-priority patent/JPH0780892B2/ja
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES8700222A1 publication Critical patent/ES8700222A1/es
Publication of ES547300A0 publication Critical patent/ES547300A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Steroid Compounds (AREA)
ES547300A 1983-10-04 1985-08-29 Nuevo procedimiento para la fabricacion de acido 7-beta- (carboxialquenoilamino)-3-cefem-4-carboxilico Expired ES8700222A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP58186601A JPS6078987A (ja) 1983-10-04 1983-10-04 アクリルアミドセフアロスポリン類
JP59018563A JPS60163884A (ja) 1984-02-03 1984-02-03 カルボキシアルケンアミドセフアロスポリン
JP59100890A JPH0780892B2 (ja) 1984-05-18 1984-05-18 カルボキシアルケンアミドセフアロスポリン

Publications (2)

Publication Number Publication Date
ES8700222A1 ES8700222A1 (es) 1986-11-16
ES547300A0 true ES547300A0 (es) 1986-11-16

Family

ID=27282263

Family Applications (3)

Application Number Title Priority Date Filing Date
ES536502A Expired ES8604602A1 (es) 1983-10-04 1984-10-04 Procedimiento para la fabricacion de acido 7beta-(carboxialquenoilamino)-3-cefem-4-carboxilico
ES547300A Expired ES8700222A1 (es) 1983-10-04 1985-08-29 Nuevo procedimiento para la fabricacion de acido 7-beta- (carboxialquenoilamino)-3-cefem-4-carboxilico
ES547301A Expired ES8605278A1 (es) 1983-10-04 1985-08-29 Procedimiento perfeccionado para la fabricacion de acido 7- beta-(carboxialquenoilamino)-3-cefem-4-carboxilico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES536502A Expired ES8604602A1 (es) 1983-10-04 1984-10-04 Procedimiento para la fabricacion de acido 7beta-(carboxialquenoilamino)-3-cefem-4-carboxilico

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES547301A Expired ES8605278A1 (es) 1983-10-04 1985-08-29 Procedimiento perfeccionado para la fabricacion de acido 7- beta-(carboxialquenoilamino)-3-cefem-4-carboxilico

Country Status (22)

Country Link
US (3) US4634697A (es)
EP (1) EP0136721B1 (es)
KR (2) KR880002376B1 (es)
AR (1) AR242392A1 (es)
AT (1) ATE99311T1 (es)
AU (2) AU575854B2 (es)
CA (2) CA1238910A (es)
DE (2) DE136721T1 (es)
DK (1) DK171043B1 (es)
ES (3) ES8604602A1 (es)
FI (1) FI82057C (es)
GB (3) GB2154580B (es)
GR (1) GR80544B (es)
HU (1) HU193298B (es)
IE (1) IE57744B1 (es)
IL (3) IL84653A (es)
MX (1) MX174328B (es)
NL (1) NL940013I2 (es)
NO (2) NO173238C (es)
NZ (2) NZ209634A (es)
PH (2) PH20223A (es)
PT (1) PT79287A (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
JP2501785B2 (ja) * 1984-07-09 1996-05-29 明治製菓株式会社 新規セフアロスポリン系化合物
JPS6124580A (ja) * 1984-07-12 1986-02-03 Shionogi & Co Ltd アミノチアゾリルグルタル酸誘導体の製造方法
JPS6153272A (ja) * 1984-08-24 1986-03-17 Shionogi & Co Ltd グルタル酸誘導体の製法
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters
PT82468B (en) 1985-04-30 1988-03-23 Lilly Co Eli Process for preparing 7-substituted bycyclic pyrazolidinones
US4731362A (en) * 1985-08-05 1988-03-15 Shionogi & Co., Ltd. Alkylcarbamoyloxymethylcephem compounds
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
DE3745094B4 (de) * 1986-07-02 2004-12-30 Shionogi & Co., Ltd. Ein kristallines Hydrat der 7ß-[(Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carbonsäure enthaltende Hartgelatinekapsel-Zusammensetzung
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
AT396652B (de) * 1986-07-02 1993-11-25 Shionogi & Co Verfahren zur herstellung von hartgelatinekapsel-zusammensetzungen
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
US5242913A (en) * 1987-03-11 1993-09-07 Pfizer Inc. Substituted 3-cephem compounds as antibacterial agents
WO1993013108A1 (en) * 1987-03-11 1993-07-08 Susumu Nakanishi Substituted 3-cephem compounds as antibacterial agents
US4820832A (en) * 1988-03-23 1989-04-11 Eli Lilly And Company Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5245027A (en) * 1989-11-21 1993-09-14 Bristol-Myers Squibb Company 3-fluorosulfonyloxyceph-3-em compounds
US5612048A (en) * 1994-11-22 1997-03-18 Amvac Chemical Corporation Stabilized moisture-sensitive pesticide composition and method of making
US5571910A (en) * 1994-12-09 1996-11-05 Schering Corporation Process for the preparation of intermediates useful in the synthesis of cephalosporins
JPH101482A (ja) * 1996-06-13 1998-01-06 Otsuka Chem Co Ltd ３−ノルセフェム化合物の製造法
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
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US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US8225458B1 (en) 2001-07-13 2012-07-24 Hoffberg Steven M Intelligent door restraint
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JP5654990B2 (ja) 2008-08-20 2015-01-14 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． アゾ置換ピリジンおよびピリミジン誘導体ならびにそれらのウイルス感染の治療における使用
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Also Published As

Publication number Publication date
IL84653A (en) 1990-08-31
NL940013I2 (nl) 1999-06-01
GR80544B (en) 1985-02-05
FI82057B (fi) 1990-09-28
EP0136721A2 (en) 1985-04-10
ES8700222A1 (es) 1986-11-16
DE3486259T2 (de) 1994-07-21
GB8726623D0 (en) 1987-12-16
NO173238C (no) 1993-11-17
NO176567B (no) 1995-01-16
FI82057C (fi) 1991-01-10
AU3330084A (en) 1985-05-09
GB2198727A (en) 1988-06-22
NO843956L (no) 1985-04-09
NZ209634A (en) 1988-07-28
DE3486259D1 (de) 1994-02-10
PH21766A (en) 1988-02-18
DK474584D0 (da) 1984-10-03
KR850002989A (ko) 1985-05-28
IL73159A (en) 1990-08-31
AU1619488A (en) 1988-08-11
PT79287A (en) 1984-11-01
EP0136721B1 (en) 1993-12-29
HU193298B (en) 1987-09-28
CA1272713A (en) 1990-08-14
FI843871L (fi) 1985-04-05
AU601842B2 (en) 1990-09-20
KR880002684B1 (ko) 1988-12-20
AU575854B2 (en) 1988-08-11
NL940013I1 (nl) 1994-08-16
NO853806L (no) 1985-04-09
PH20223A (en) 1986-10-23
US4912224A (en) 1990-03-27
NO173238B (no) 1993-08-09
EP0136721A3 (en) 1986-01-22
ES547301A0 (es) 1986-03-16
DK474584A (da) 1985-04-05
US4748170A (en) 1988-05-31
IL84653A0 (en) 1988-04-29
IE842524L (en) 1985-04-04
ES536502A0 (es) 1986-02-01
IL73159A0 (en) 1985-01-31
GB2190914A (en) 1987-12-02
GB8700123D0 (en) 1987-02-11
MX174328B (es) 1994-05-09
GB8424923D0 (en) 1984-11-07
ES8604602A1 (es) 1986-02-01
GB2154580A (en) 1985-09-11
DE136721T1 (de) 1985-08-29
FI843871A0 (fi) 1984-10-02
ATE99311T1 (de) 1994-01-15
US4634697A (en) 1987-01-06
IE57744B1 (en) 1993-03-24
CA1238910A (en) 1988-07-05
DK171043B1 (da) 1996-04-29
HUT36129A (en) 1985-08-28
NO176567C (no) 1995-04-26
ES8605278A1 (es) 1986-03-16
AR242392A1 (es) 1993-03-31
GB2190914B (en) 1988-08-17
NZ218741A (en) 1988-07-28
GB2198727B (en) 1988-11-16
CA1272713C (es) 1990-08-14
GB2154580B (en) 1988-08-17
KR880002376B1 (ko) 1988-11-03

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