IL163863A0 - Form of presentation for3-Ä(2-äÄ4-(hexyloxycarbonylamino-imino-methyl)-phenylaminoÜmethylü-1-methyl-1H-benzimidaz - Google Patents

Form of presentation for3-Ä(2-äÄ4-(hexyloxycarbonylamino-imino-methyl)-phenylaminoÜmethylü-1-methyl-1H-benzimidaz

Info

Publication number
IL163863A0
IL163863A0 IL16386303A IL16386303A IL163863A0 IL 163863 A0 IL163863 A0 IL 163863A0 IL 16386303 A IL16386303 A IL 16386303A IL 16386303 A IL16386303 A IL 16386303A IL 163863 A0 IL163863 A0 IL 163863A0
Authority
IL
Israel
Prior art keywords
methyl
phenylaminoümethylü
benzimidaz
for3
hexyloxycarbonylamino
Prior art date
Application number
IL16386303A
Other languages
English (en)
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27789735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL163863(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10209985A external-priority patent/DE10209985A1/de
Priority claimed from DE2002145624 external-priority patent/DE10245624A1/de
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IL163863A0 publication Critical patent/IL163863A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL16386303A 2002-03-07 2003-03-03 Form of presentation for3-Ä(2-äÄ4-(hexyloxycarbonylamino-imino-methyl)-phenylaminoÜmethylü-1-methyl-1H-benzimidaz IL163863A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10209985A DE10209985A1 (de) 2002-03-07 2002-03-07 Oral zu applizierende Darreichungsform für 3-[(2-{[4-(Hexyloxycarbonylaminoimino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propinsäure-ethylester und dessen Salze
DE2002145624 DE10245624A1 (de) 2002-09-30 2002-09-30 Oral zu applizierende Darreichungsform für 3-[(2-{[4-(Hexyloxycarbonylaminoimino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2yl-amino]-propinsäure-ethylester und dessen Salze
PCT/EP2003/002141 WO2003074056A1 (fr) 2002-03-07 2003-03-03 Forme de presentation a administrer par voie orale pour l'ethylester d'acide 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionique et ses sels

Publications (1)

Publication Number Publication Date
IL163863A0 true IL163863A0 (en) 2005-12-18

Family

ID=27789735

Family Applications (3)

Application Number Title Priority Date Filing Date
IL16386303A IL163863A0 (en) 2002-03-07 2003-03-03 Form of presentation for3-Ä(2-äÄ4-(hexyloxycarbonylamino-imino-methyl)-phenylaminoÜmethylü-1-methyl-1H-benzimidaz
IL163863A IL163863A (en) 2002-03-07 2004-09-01 Pharmaceutical composition for oral administration of 3-[(2 -{[4- (hexyloxycarbonylamino- imino- methyl)-phenylamino]methyl}-1- methyl-1h- benzimidazol-5- carbonyl)- pyridin- 2- yl- amino] propionic acid ethyl ester
IL209368A IL209368A (en) 2002-03-07 2010-11-17 Ethylsulfonate Salt of Ethyl 3 - [(2– {4– (xyloxycarbonylamino – amino – methyl) –phenylamino] –methyl} –1 – methyl – H1– benzamideimzole – 5 – carbonyl) –pyridine – 2 – ile-amino] propionate and preparation Pharmacy containing it

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL163863A IL163863A (en) 2002-03-07 2004-09-01 Pharmaceutical composition for oral administration of 3-[(2 -{[4- (hexyloxycarbonylamino- imino- methyl)-phenylamino]methyl}-1- methyl-1h- benzimidazol-5- carbonyl)- pyridin- 2- yl- amino] propionic acid ethyl ester
IL209368A IL209368A (en) 2002-03-07 2010-11-17 Ethylsulfonate Salt of Ethyl 3 - [(2– {4– (xyloxycarbonylamino – amino – methyl) –phenylamino] –methyl} –1 – methyl – H1– benzamideimzole – 5 – carbonyl) –pyridine – 2 – ile-amino] propionate and preparation Pharmacy containing it

Country Status (36)

Country Link
US (2) US20190231766A1 (fr)
EP (2) EP1485094B2 (fr)
JP (3) JP3866715B2 (fr)
KR (1) KR101005716B1 (fr)
CN (1) CN100528157C (fr)
AR (2) AR042861A1 (fr)
AT (1) ATE540943T1 (fr)
AU (1) AU2003210400B8 (fr)
BR (1) BRPI0306559B8 (fr)
CA (1) CA2476054C (fr)
CL (1) CL2009001915A1 (fr)
CO (1) CO5611149A2 (fr)
CY (4) CY1112796T1 (fr)
DE (1) DE122012000047I1 (fr)
DK (2) DK1485094T4 (fr)
EA (1) EA009664B1 (fr)
EC (1) ECSP045331A (fr)
ES (2) ES2380704T3 (fr)
HK (1) HK1078792A1 (fr)
HR (1) HRP20040807B1 (fr)
IL (3) IL163863A0 (fr)
LU (2) LU92025I2 (fr)
ME (1) ME00325B (fr)
MX (1) MXPA04008542A (fr)
MY (1) MY143734A (fr)
NO (3) NO326918B1 (fr)
NZ (2) NZ546367A (fr)
PE (1) PE20030889A1 (fr)
PL (2) PL210862B1 (fr)
PT (2) PT1870100E (fr)
RS (1) RS52088B (fr)
SG (1) SG146435A1 (fr)
SI (2) SI1485094T2 (fr)
TW (1) TWI293879B (fr)
WO (1) WO2003074056A1 (fr)
ZA (1) ZA200406071B (fr)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
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DE10339862A1 (de) * 2003-08-29 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel
DE10341043A1 (de) * 2003-09-03 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue oral zu applizierende Darreichungsform für 3-[(2-{[4-Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester und dessen Salze
JPWO2005113010A1 (ja) * 2004-05-24 2008-07-31 クオリカプス株式会社 表面改質および溶解性が改善された硬カプセル
DE102004062864A1 (de) 2004-12-21 2006-06-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Folienbehälter
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DE102005025728A1 (de) 2005-06-04 2006-12-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Polymorphe von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-Propionsäure-ethylester
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EP2722034B1 (fr) 2012-10-19 2020-09-16 Sanovel Ilac Sanayi ve Ticaret A.S. Formulations pharmaceutiques orales comprenant du dabigatran
WO2014060545A1 (fr) 2012-10-19 2014-04-24 Sanovel Ilac Sanayi Ve Ticaret A.S. Compositions pharmaceutiques de dabigatran sous forme de base libre
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WO2015145462A1 (fr) 2014-03-26 2015-10-01 Cadila Healthcare Limited Compositions pharmaceutiques de dabigatran
WO2015155297A1 (fr) 2014-04-11 2015-10-15 Sanovel Ilac Sanayi Ve Ticaret A.S. Combinaisons pharmaceutiques de dabigatran et d'antagonistes du récepteur h2
EP2933002A1 (fr) 2014-04-11 2015-10-21 Sanovel Ilac Sanayi ve Ticaret A.S. Compositions pharmaceutiques comprenants de dabigratan et des inhibiteurs de la pompe à protons
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CN105640909B (zh) 2014-11-14 2019-09-20 正大天晴药业集团股份有限公司 一种含有达比加群酯的药用组合物
CN106924256B (zh) * 2015-12-25 2022-08-19 深圳市药欣生物科技有限公司 药物组合物及其制备方法
CN105797162B (zh) * 2014-12-31 2022-10-25 昆明积大制药股份有限公司 药用辅料表面改性方法
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CN106999434B (zh) * 2015-04-08 2020-05-22 杭州领业医药科技有限公司 一种含半胱氨酸盐酸盐的微丸及其制备方法
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