IL136738A0 - Inhibition of p38 kinase activity using substituted heterocyclic ureas - Google Patents
Inhibition of p38 kinase activity using substituted heterocyclic ureasInfo
- Publication number
- IL136738A0 IL136738A0 IL13673898A IL13673898A IL136738A0 IL 136738 A0 IL136738 A0 IL 136738A0 IL 13673898 A IL13673898 A IL 13673898A IL 13673898 A IL13673898 A IL 13673898A IL 136738 A0 IL136738 A0 IL 136738A0
- Authority
- IL
- Israel
- Prior art keywords
- inhibition
- kinase activity
- substituted heterocyclic
- heterocyclic ureas
- ureas
- Prior art date
Links
- 235000013877 carbamide Nutrition 0.000 title abstract 2
- -1 heterocyclic ureas Chemical class 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- 102000002574 p38 Mitogen-Activated Protein Kinases Human genes 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 230000003157 cancerolytic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99575097A | 1997-12-22 | 1997-12-22 | |
| PCT/US1998/026080 WO1999032111A1 (en) | 1997-12-22 | 1998-12-22 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL136738A0 true IL136738A0 (en) | 2001-06-14 |
Family
ID=25542167
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13673898A IL136738A0 (en) | 1997-12-22 | 1998-12-22 | Inhibition of p38 kinase activity using substituted heterocyclic ureas |
| IL136738A IL136738A (en) | 1997-12-22 | 2000-06-12 | USE OF SUBSTITUTED HETEROCYCLIC UREAS FOR THE PREPARATION OF MEDICAMENTS FOR TREATING A DISEASE MEDIATED BY p38 OTHER THAN CANCER |
| IL170201A IL170201A (en) | 1997-12-22 | 2005-08-10 | Sustituted heterocyclic ureas and pharmaceutical compositions comprising them |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL136738A IL136738A (en) | 1997-12-22 | 2000-06-12 | USE OF SUBSTITUTED HETEROCYCLIC UREAS FOR THE PREPARATION OF MEDICAMENTS FOR TREATING A DISEASE MEDIATED BY p38 OTHER THAN CANCER |
| IL170201A IL170201A (en) | 1997-12-22 | 2005-08-10 | Sustituted heterocyclic ureas and pharmaceutical compositions comprising them |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1041982B1 (enExample) |
| JP (1) | JP4403482B2 (enExample) |
| AT (1) | ATE529109T1 (enExample) |
| AU (1) | AU739642B2 (enExample) |
| CA (1) | CA2315720A1 (enExample) |
| DE (1) | DE1041982T1 (enExample) |
| ES (1) | ES2154253T3 (enExample) |
| IL (3) | IL136738A0 (enExample) |
| MX (1) | MXPA00006233A (enExample) |
| WO (1) | WO1999032111A1 (enExample) |
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-
1998
- 1998-12-22 JP JP2000525102A patent/JP4403482B2/ja not_active Expired - Fee Related
- 1998-12-22 DE DE1041982T patent/DE1041982T1/de active Pending
- 1998-12-22 EP EP98964709A patent/EP1041982B1/en not_active Expired - Lifetime
- 1998-12-22 IL IL13673898A patent/IL136738A0/xx active IP Right Grant
- 1998-12-22 MX MXPA00006233A patent/MXPA00006233A/es not_active Application Discontinuation
- 1998-12-22 CA CA002315720A patent/CA2315720A1/en not_active Abandoned
- 1998-12-22 WO PCT/US1998/026080 patent/WO1999032111A1/en not_active Ceased
- 1998-12-22 AT AT98964709T patent/ATE529109T1/de not_active IP Right Cessation
- 1998-12-22 ES ES98964709T patent/ES2154253T3/es not_active Expired - Lifetime
- 1998-12-22 AU AU19971/99A patent/AU739642B2/en not_active Ceased
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2000
- 2000-06-12 IL IL136738A patent/IL136738A/en not_active IP Right Cessation
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2005
- 2005-08-10 IL IL170201A patent/IL170201A/en not_active IP Right Cessation
Also Published As
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| ATE529109T1 (de) | 2011-11-15 |
| MXPA00006233A (es) | 2002-09-18 |
| JP4403482B2 (ja) | 2010-01-27 |
| ES2154253T1 (es) | 2001-04-01 |
| EP1041982B1 (en) | 2011-10-19 |
| IL170201A (en) | 2006-12-31 |
| JP2001526223A (ja) | 2001-12-18 |
| DE1041982T1 (de) | 2001-06-07 |
| IL136738A (en) | 2007-06-17 |
| EP1041982A4 (en) | 2006-06-14 |
| CA2315720A1 (en) | 1999-07-01 |
| AU739642B2 (en) | 2001-10-18 |
| EP1041982A1 (en) | 2000-10-11 |
| ES2154253T3 (es) | 2012-01-27 |
| AU1997199A (en) | 1999-07-12 |
| WO1999032111A1 (en) | 1999-07-01 |
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