ES2154253T3 - Inhibición de la actividad de p38 cinasa usando ureas heterocíclicas sustituidas. - Google Patents

Inhibición de la actividad de p38 cinasa usando ureas heterocíclicas sustituidas. Download PDF

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Publication number
ES2154253T3
ES2154253T3 ES98964709T ES98964709T ES2154253T3 ES 2154253 T3 ES2154253 T3 ES 2154253T3 ES 98964709 T ES98964709 T ES 98964709T ES 98964709 T ES98964709 T ES 98964709T ES 2154253 T3 ES2154253 T3 ES 2154253T3
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Spain
Prior art keywords
substituted
tert
butyl
urea
pyrazolyl
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ES98964709T
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English (en)
Spanish (es)
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ES2154253T1 (es
Inventor
Jacques Dumas
Uday Khire
Timothy B. Lowinger
Holger Paulsen
Bernd Riedl
William J. Scott
Roger A. Smith
Jill E. Wood
Holia Hatoum-Mokdad
Jeffrey Johnson
Wendy Lee
Aniko Redman
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Bayer Healthcare LLC
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Bayer Healthcare LLC
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
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ES98964709T 1997-12-22 1998-12-22 Inhibición de la actividad de p38 cinasa usando ureas heterocíclicas sustituidas. Expired - Lifetime ES2154253T3 (es)

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