IL129866A - Pyrazoles are parasiticides, a process for their preparation and preparations containing them - Google Patents

Pyrazoles are parasiticides, a process for their preparation and preparations containing them

Info

Publication number
IL129866A
IL129866A IL12986697A IL12986697A IL129866A IL 129866 A IL129866 A IL 129866A IL 12986697 A IL12986697 A IL 12986697A IL 12986697 A IL12986697 A IL 12986697A IL 129866 A IL129866 A IL 129866A
Authority
IL
Israel
Prior art keywords
halo
dichloro
cyano
hydrogen
compound
Prior art date
Application number
IL12986697A
Other languages
English (en)
Hebrew (he)
Other versions
IL129866A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625290.3A external-priority patent/GB9625290D0/en
Priority claimed from GBGB9702235.4A external-priority patent/GB9702235D0/en
Priority claimed from GBGB9712045.5A external-priority patent/GB9712045D0/en
Application filed by Pfizer filed Critical Pfizer
Priority to IL15008897A priority Critical patent/IL150088A/en
Publication of IL129866A0 publication Critical patent/IL129866A0/xx
Publication of IL129866A publication Critical patent/IL129866A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL12986697A 1996-12-05 1997-11-25 Pyrazoles are parasiticides, a process for their preparation and preparations containing them IL129866A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL15008897A IL150088A (en) 1996-12-05 1997-11-25 Parasiticidal pyrazoles

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9625290.3A GB9625290D0 (en) 1996-12-05 1996-12-05 Parasiticidal agents
GBGB9702235.4A GB9702235D0 (en) 1997-02-04 1997-02-04 Parasiticidal agents
GBGB9712045.5A GB9712045D0 (en) 1997-06-10 1997-06-10 Parasiticidal agents
PCT/EP1997/006697 WO1998024767A1 (en) 1996-12-05 1997-11-25 Parasiticidal pyrazoles

Publications (2)

Publication Number Publication Date
IL129866A0 IL129866A0 (en) 2000-02-29
IL129866A true IL129866A (en) 2004-05-12

Family

ID=27268619

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12986697A IL129866A (en) 1996-12-05 1997-11-25 Pyrazoles are parasiticides, a process for their preparation and preparations containing them

Country Status (40)

Country Link
US (2) US6075043A (ja)
EP (1) EP0946515B1 (ja)
JP (2) JP3950483B2 (ja)
KR (1) KR100354311B1 (ja)
CN (1) CN1106386C (ja)
AR (1) AR013879A1 (ja)
AT (1) ATE233736T1 (ja)
AU (1) AU720705B2 (ja)
BG (1) BG64127B1 (ja)
BR (1) BR9713565A (ja)
CA (1) CA2273951C (ja)
CO (1) CO5031251A1 (ja)
CZ (1) CZ295295B6 (ja)
DE (1) DE69719547T2 (ja)
DK (1) DK0946515T3 (ja)
DZ (1) DZ2360A1 (ja)
EA (1) EA002278B1 (ja)
ES (1) ES2191870T3 (ja)
HK (1) HK1029111A1 (ja)
HR (1) HRP970663B1 (ja)
HU (1) HUP0000544A3 (ja)
ID (1) ID21556A (ja)
IL (1) IL129866A (ja)
IS (1) IS1982B (ja)
MA (1) MA24414A1 (ja)
MY (1) MY117021A (ja)
NO (2) NO313518B1 (ja)
NZ (1) NZ335611A (ja)
OA (1) OA11055A (ja)
PA (1) PA8442101A1 (ja)
PE (1) PE20199A1 (ja)
PL (1) PL190926B1 (ja)
PT (1) PT946515E (ja)
RS (1) RS49720B (ja)
SK (1) SK285203B6 (ja)
TN (1) TNSN97197A1 (ja)
TW (1) TW524667B (ja)
UA (1) UA60321C2 (ja)
UY (2) UY24798A1 (ja)
WO (1) WO1998024767A1 (ja)

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AR021608A1 (es) * 1998-12-11 2002-07-31 Merial Ltd Represion de artropodos en animales
GB9916052D0 (en) * 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
CN1939909A (zh) 1999-12-02 2007-04-04 阿温提斯作物科学股份有限公司 控制动物中的节肢动物
AU2003218758A1 (en) * 2002-03-14 2003-09-22 Syngenta Participations Ag Derivatives of 1-phenyl-3-phenylpyrazole as herbicides
CH697663B1 (de) * 2003-01-07 2009-01-15 Lanxess Deutschland Gmbh Pyrazolylalkine.
WO2005023773A1 (en) * 2003-09-04 2005-03-17 Pfizer Limited Process for the preparation of substituted aryl pyrazoles
US7514464B2 (en) * 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
GB0329314D0 (en) * 2003-12-18 2004-01-21 Pfizer Ltd Substituted arylpyrazoles
WO2005090313A1 (en) 2004-03-18 2005-09-29 Pfizer Limited N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
US20070149464A1 (en) * 2005-06-15 2007-06-28 Pfizer Inc. Combination
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
ATE456557T1 (de) 2005-06-15 2010-02-15 Pfizer Ltd Substituierte arylpyrazole zur verwendung gegen parasiten
US7645786B2 (en) 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
MX2008000250A (es) 2005-07-06 2008-03-19 Sepracor Inc Combinaciones de eszopiclona y trans-4-(3,4-diclorofenil)-1,2,3,4- tetrahidro-n-metil-1-naftalenamina o trans 4-(3,4-diclorofenil)-1, 2,3,4-tetrahidro-1-naftalenamina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y
EP1783114A1 (en) * 2005-11-03 2007-05-09 Novartis AG N-(hetero)aryl indole derivatives as pesticides
DE102006061537A1 (de) 2006-12-27 2008-07-03 Bayer Healthcare Ag Mittel zur Bekämpfung von Parasiten an Tieren
DE102006061538A1 (de) 2006-12-27 2008-07-03 Bayer Healthcare Ag Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren
JP2013523805A (ja) 2010-04-08 2013-06-17 ゾエティス・エルエルシー 殺虫剤および殺ダニ剤としての置換3,5−ジフェニル−イソオキサゾリン誘導体
JP5409968B2 (ja) 2010-08-05 2014-02-05 ゾエティス・エルエルシー 駆虫剤としてのイソオキサゾリン誘導体
EP2619189B1 (en) 2010-09-24 2020-04-15 Zoetis Services LLC Isoxazoline oximes as antiparasitic agents
RU2566083C3 (ru) 2011-03-10 2017-11-09 Зоетис Сервисиз ЛЛК Спироциклические производные изоксазолина в качестве противопаразитарных агентов
EP2688876A1 (en) 2011-03-22 2014-01-29 Zoetis Llc Isoxazoline derivatives as antiparasitic agents
US9925167B2 (en) 2011-06-30 2018-03-27 Hansen-Ab Gmbh Agents for the control of parasites on animals
MX336430B (es) 2012-02-03 2016-01-18 Zoetis Services Llc Derivados de dihidrofurano-azetadina como agentes antiparasitarios.
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
US9073912B2 (en) 2012-05-09 2015-07-07 Zoetis Services Llc Azetidine derivatives as antiparasitic agents
WO2014093481A1 (en) 2012-12-12 2014-06-19 Zoetis Llc Phenylpyrazole injectable compositions
CN111050750A (zh) 2017-08-24 2020-04-21 诺沃挪第克公司 Glp-1组合物及其用途
CN111116478B (zh) * 2019-12-18 2021-10-26 浙江金伯士药业有限公司 一种兽用抗生素维吉霉素中间体的制备方法
MX2022009523A (es) 2020-02-18 2022-09-09 Novo Nordisk As Formulaciones farmaceuticas.
CN115894374A (zh) * 2023-02-16 2023-04-04 广州佳途科技股份有限公司 一种氟甲腈的制备方法及其应用

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FR2739255B1 (fr) * 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
DE69627281T2 (de) * 1995-12-19 2003-11-13 Bayer Cropscience Sa Neue 1-Aryl Pyrazol Derivate und ihre Verwendung als Schädlingsbekämpfungsmittel
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TW524667B (en) 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
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Also Published As

Publication number Publication date
NO313518B1 (no) 2002-10-14
KR100354311B1 (ko) 2002-09-28
HK1029111A1 (en) 2001-03-23
ES2191870T3 (es) 2003-09-16
MA24414A1 (fr) 1998-07-01
IL129866A0 (en) 2000-02-29
EP0946515A1 (en) 1999-10-06
AU5485998A (en) 1998-06-29
PL333922A1 (en) 2000-01-31
NO992736D0 (no) 1999-06-04
HRP970663B1 (en) 2003-10-31
PE20199A1 (es) 1999-03-05
OA11055A (en) 2002-03-07
PA8442101A1 (es) 2000-05-24
NZ335611A (en) 2001-01-26
CZ195199A3 (cs) 2000-08-16
YU25299A (sh) 2002-10-18
HUP0000544A3 (en) 2002-01-28
NO992732L (no) 1999-08-05
JP2000505812A (ja) 2000-05-16
DE69719547T2 (de) 2003-10-02
EA199900447A1 (ru) 2000-02-28
BG64127B1 (bg) 2004-01-30
MY117021A (en) 2004-04-30
WO1998024767A1 (en) 1998-06-11
UY24923A1 (es) 1998-09-01
DK0946515T3 (da) 2003-07-14
IS5050A (is) 1999-05-11
IS1982B (is) 2005-01-14
US6075043A (en) 2000-06-13
CN1258282A (zh) 2000-06-28
PT946515E (pt) 2003-06-30
CO5031251A1 (es) 2001-04-27
CN1106386C (zh) 2003-04-23
SK74099A3 (en) 2001-02-12
US6268509B1 (en) 2001-07-31
AU720705B2 (en) 2000-06-08
JP3950483B2 (ja) 2007-08-01
BR9713565A (pt) 2000-03-14
DZ2360A1 (fr) 2002-12-28
AR013879A1 (es) 2001-01-31
TNSN97197A1 (fr) 2005-03-15
DE69719547D1 (de) 2003-04-10
HRP970663A2 (en) 1998-10-31
HUP0000544A2 (hu) 2000-06-28
SK285203B6 (sk) 2006-08-03
ID21556A (id) 1999-06-24
EA002278B1 (ru) 2002-02-28
PL190926B1 (pl) 2006-02-28
RS49720B (sr) 2007-12-31
UA60321C2 (uk) 2003-10-15
KR20000057432A (ko) 2000-09-15
CZ295295B6 (cs) 2005-06-15
CA2273951A1 (en) 1998-06-11
EP0946515B1 (en) 2003-03-05
JP2007211016A (ja) 2007-08-23
TW524667B (en) 2003-03-21
ATE233736T1 (de) 2003-03-15
CA2273951C (en) 2003-04-01
BG103454A (en) 2000-01-31
UY24798A1 (es) 2000-09-29
NO992732D0 (no) 1999-06-04

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