HUS1300028I1 - Sztiril-piridin-származékok és alkalmazásuk amyloid-plakkok megkötésére és leképezésére - Google Patents
Sztiril-piridin-származékok és alkalmazásuk amyloid-plakkok megkötésére és leképezéséreInfo
- Publication number
- HUS1300028I1 HUS1300028I1 HUS1300028C HUS1300028C HUS1300028I1 HU S1300028 I1 HUS1300028 I1 HU S1300028I1 HU S1300028 C HUS1300028 C HU S1300028C HU S1300028 C HUS1300028 C HU S1300028C HU S1300028 I1 HUS1300028 I1 HU S1300028I1
- Authority
- HU
- Hungary
- Prior art keywords
- binding
- amyloid plaques
- styrylpyridine
- imaging amyloid
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78715606P | 2006-03-30 | 2006-03-30 | |
PCT/US2007/007400 WO2007126733A2 (en) | 2006-03-30 | 2007-03-26 | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques |
EP07753982A EP1999109B1 (en) | 2006-03-30 | 2007-03-26 | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques |
Publications (1)
Publication Number | Publication Date |
---|---|
HUS1300028I1 true HUS1300028I1 (hu) | 2017-08-28 |
Family
ID=38326579
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE11152124A HUE032660T2 (hu) | 2006-03-30 | 2007-03-26 | Sztirilpiridin-származékok és azok alkalmazása amiloid plakkok megkötésére és leképezésére |
HUS1300028C HUS1300028I1 (hu) | 2006-03-30 | 2013-06-27 | Sztiril-piridin-származékok és alkalmazásuk amyloid-plakkok megkötésére és leképezésére |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE11152124A HUE032660T2 (hu) | 2006-03-30 | 2007-03-26 | Sztirilpiridin-származékok és azok alkalmazása amiloid plakkok megkötésére és leképezésére |
Country Status (34)
Country | Link |
---|---|
US (3) | US7687052B2 (hu) |
EP (3) | EP2363391A1 (hu) |
JP (1) | JP5290954B2 (hu) |
KR (1) | KR101376807B1 (hu) |
CN (1) | CN101522624B (hu) |
AT (1) | ATE539060T1 (hu) |
AU (1) | AU2007243712B2 (hu) |
BR (1) | BRPI0710225B1 (hu) |
CA (1) | CA2644530C (hu) |
CR (1) | CR10329A (hu) |
CY (3) | CY1113048T1 (hu) |
DK (2) | DK2363392T3 (hu) |
EA (1) | EA017898B1 (hu) |
EC (1) | ECSP088783A (hu) |
ES (2) | ES2628882T3 (hu) |
FR (1) | FR13C0034I2 (hu) |
GT (1) | GT200800201A (hu) |
HR (2) | HRP20120135T1 (hu) |
HU (2) | HUE032660T2 (hu) |
IL (1) | IL193567A (hu) |
LT (1) | LT2363392T (hu) |
LU (1) | LU92232I2 (hu) |
MX (1) | MX2008012527A (hu) |
NO (2) | NO342090B1 (hu) |
NZ (1) | NZ570887A (hu) |
PL (2) | PL2363392T3 (hu) |
PT (2) | PT1999109E (hu) |
RS (2) | RS56171B1 (hu) |
SG (1) | SG173338A1 (hu) |
SI (2) | SI1999109T1 (hu) |
TW (1) | TWI399366B (hu) |
UA (1) | UA97802C2 (hu) |
WO (1) | WO2007126733A2 (hu) |
ZA (1) | ZA200807955B (hu) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007243712B2 (en) * | 2006-03-30 | 2013-01-10 | The Trustees Of The University Of Pennsylvania | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques |
JP5322180B2 (ja) * | 2007-07-04 | 2013-10-23 | 国立大学法人東北大学 | フッ素およびヒドロキシ基で置換されたアルコキシ基を有するpetプローブ |
US8557222B2 (en) | 2008-04-04 | 2013-10-15 | Avid Radiopharmaceuticals, Inc. | Radiopharmaceutical imaging of neurodegenerative diseases |
UA105914C2 (uk) * | 2008-12-31 | 2014-07-10 | Евід Рейдіофармасьютікалз, Інк. | Синтез стирилпіридину, міченого радіоізотопом 18f, з тозилатного прекурсора та стабільна фармацевтична композиція на його основі |
CA2767475A1 (en) * | 2009-07-10 | 2011-01-13 | Bayer Pharma Aktiengesellschaft | Usage of low to medium-pressure liquid chromatography for the purification of radiotracers |
US20120263646A1 (en) | 2009-10-15 | 2012-10-18 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
EA022447B1 (ru) * | 2009-12-23 | 2016-01-29 | Пирамаль Имэджинг Са | Композиции, приемлемые для рет-визуализации при помощи гидрофобных рет-агентов |
WO2011141515A1 (en) | 2010-05-14 | 2011-11-17 | Bayer Pharma Aktiengesellschaft | Diagnostic agents for amyloid beta imaging |
MX2012014116A (es) * | 2010-06-04 | 2013-08-08 | Piramal Imaging Sa | Metodo para la produccion de ligandos beta amiloide marcados con 18f. |
SG185785A1 (en) * | 2010-06-04 | 2013-01-30 | Piramal Imaging Sa | Method for production of f-18 labeled amyloid beta ligand |
ES2642086T5 (es) | 2010-06-04 | 2020-04-13 | Life Molecular Imaging Sa | Procedimiento para la producción de ligandos de beta amiloide marcados con F-18 |
TWI504414B (zh) | 2010-06-04 | 2015-10-21 | Bayer Schering Pharma Ag | 生產F-18標記之Aβ配位體之方法 |
CN101891674B (zh) * | 2010-06-24 | 2012-11-14 | 山东大学 | 4-苯乙烯基吡啶类化合物及其制备方法与应用 |
EP2627361B1 (en) * | 2010-10-12 | 2017-09-20 | Mayo Foundation For Medical Education And Research | Imaging of meningiomas using phenylbenzothiazole, stilbene, or biphenylalkyne derivatives |
US20140079635A1 (en) * | 2011-03-30 | 2014-03-20 | Case Western Reserve University | Molecular probes for detecting lipid composition |
CA3058702C (en) | 2011-04-21 | 2023-11-07 | Massoud Akhtari | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles |
MX2014004274A (es) | 2011-10-19 | 2014-07-09 | Piramal Imaging Sa | METODO MEJORADO PARA LA PRODUCCION DE LIGANDOS Aß MARCADOS CON F-18. |
SG10201608370TA (en) | 2012-04-10 | 2016-11-29 | Lantheus Medical Imaging Inc | Radiopharmaceutical synthesis methods |
JP6099045B2 (ja) * | 2013-04-30 | 2017-03-22 | 国立大学法人京都大学 | トリアゾロピリミジン誘導体化合物 |
JP2014218454A (ja) * | 2013-05-07 | 2014-11-20 | 日本メジフィジックス株式会社 | スチリルピリジン誘導体化合物 |
JP6041751B2 (ja) * | 2013-05-07 | 2016-12-14 | 日本メジフィジックス株式会社 | スチリルピリジン誘導体化合物 |
CN103645254B (zh) * | 2013-11-28 | 2015-01-07 | 江苏省原子医学研究所 | 一种Aβ斑块显像剂前体AV45的含量分析方法 |
HUE053939T2 (hu) | 2014-05-13 | 2021-08-30 | Hoffmann La Roche | Deuterált heterociklikus vegyületek és képalkotó kontrasztanyagként való használatuk |
AU2016308189B2 (en) | 2015-08-18 | 2021-03-11 | The Regents Of The University Of California | Nitroxide containing amyloid binding agents for imaging and therapeutic uses |
US10300155B2 (en) | 2015-12-31 | 2019-05-28 | Washington University | Alpha-synuclein ligands |
CN109400615B (zh) * | 2017-08-18 | 2021-07-16 | 上海交通大学医学院附属新华医院 | 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用 |
CN108299287A (zh) * | 2018-01-02 | 2018-07-20 | 北京师范大学 | 与Aβ斑块具有高亲和力的N2S2类吡啶基苯乙烯化合物 |
CN114805190A (zh) * | 2022-06-08 | 2022-07-29 | 吉林大学第一医院 | 一种甲基苯胺类Aβ蛋白显像剂的双柱合成方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992000963A1 (en) * | 1990-07-12 | 1992-01-23 | Yoshitomi Pharmaceutical Industries, Ltd. | Styryl compounds and use thereof as medicine |
JPH0545875A (ja) * | 1991-08-08 | 1993-02-26 | Konica Corp | 感光性組成物 |
US6020436A (en) * | 1993-03-09 | 2000-02-01 | The Chromaline Corporation | Photosensitive resin composition |
TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
WO2001070667A1 (fr) * | 2000-03-22 | 2001-09-27 | Bf Research Institute, Inc. | Sonde de diagnostic par image, a base d'azobenzene substitue ou d'un analogue de celui-ci, pour les maladies imputables a l'accumulation d'amyloide et composition pour le diagnostic par image le contenant |
US8007954B2 (en) | 2000-11-09 | 2011-08-30 | The Trustees Of The University Of Pennsylvania | Use of sulfur-containing fuels for direct oxidation fuel cells |
JP2002182254A (ja) | 2000-12-18 | 2002-06-26 | Fuji Photo Film Co Ltd | 非線形光学材料とその製造方法 |
DK1432453T3 (da) * | 2001-08-27 | 2013-11-18 | Univ Pennsylvania | Stilbenderivater og anvendelse heraf til binding og billeddannelse af amyloid-plaques |
CN1672283A (zh) | 2002-06-06 | 2005-09-21 | 宾夕法尼亚州大学理事会 | 陶瓷阳极及其制造方法 |
WO2004016271A1 (en) * | 2002-08-14 | 2004-02-26 | Axxima Pharmaceuticals Ag | Pyrimidones as antiviral agents |
JP4482352B2 (ja) | 2004-03-11 | 2010-06-16 | 本田技研工業株式会社 | 固体高分子型燃料電池 |
WO2006078384A2 (en) * | 2004-12-17 | 2006-07-27 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use |
DK2213652T3 (en) * | 2004-12-17 | 2015-01-26 | Univ Pennsylvania | Stilbene AND USE THEREOF FOR BINDING AND IMAGING OF amyloid plaques |
AU2006261917A1 (en) * | 2005-06-24 | 2007-01-04 | The Trustees Of The University Of Pennsylvania | Radiolabeled-pegylation of ligands for use as imaging agents |
AU2007243712B2 (en) * | 2006-03-30 | 2013-01-10 | The Trustees Of The University Of Pennsylvania | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques |
US20080253967A1 (en) * | 2007-04-13 | 2008-10-16 | Kung Hank F | Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques |
-
2007
- 2007-03-26 AU AU2007243712A patent/AU2007243712B2/en active Active
- 2007-03-26 RS RS20170578A patent/RS56171B1/sr unknown
- 2007-03-26 PT PT07753982T patent/PT1999109E/pt unknown
- 2007-03-26 SG SG2011048477A patent/SG173338A1/en unknown
- 2007-03-26 SI SI200730865T patent/SI1999109T1/sl unknown
- 2007-03-26 DK DK11152124.1T patent/DK2363392T3/en active
- 2007-03-26 RS RS20120077A patent/RS52222B/en unknown
- 2007-03-26 JP JP2009502912A patent/JP5290954B2/ja active Active
- 2007-03-26 EP EP11152115A patent/EP2363391A1/en not_active Withdrawn
- 2007-03-26 CN CN2007800116909A patent/CN101522624B/zh active Active
- 2007-03-26 NZ NZ570887A patent/NZ570887A/en unknown
- 2007-03-26 PL PL11152124T patent/PL2363392T3/pl unknown
- 2007-03-26 CA CA2644530A patent/CA2644530C/en active Active
- 2007-03-26 BR BRPI0710225-9A patent/BRPI0710225B1/pt active IP Right Grant
- 2007-03-26 WO PCT/US2007/007400 patent/WO2007126733A2/en active Application Filing
- 2007-03-26 EA EA200870389A patent/EA017898B1/ru not_active IP Right Cessation
- 2007-03-26 SI SI200731938T patent/SI2363392T1/sl unknown
- 2007-03-26 MX MX2008012527A patent/MX2008012527A/es active IP Right Grant
- 2007-03-26 UA UAA200812698A patent/UA97802C2/uk unknown
- 2007-03-26 US US11/727,401 patent/US7687052B2/en active Active
- 2007-03-26 HU HUE11152124A patent/HUE032660T2/hu unknown
- 2007-03-26 PT PT111521241T patent/PT2363392T/pt unknown
- 2007-03-26 ES ES11152124.1T patent/ES2628882T3/es active Active
- 2007-03-26 ES ES07753982T patent/ES2378785T3/es active Active
- 2007-03-26 EP EP11152124.1A patent/EP2363392B1/en active Active
- 2007-03-26 PL PL07753982T patent/PL1999109T3/pl unknown
- 2007-03-26 DK DK07753982.3T patent/DK1999109T3/da active
- 2007-03-26 LT LTEP11152124.1T patent/LT2363392T/lt unknown
- 2007-03-26 EP EP07753982A patent/EP1999109B1/en active Active
- 2007-03-26 AT AT07753982T patent/ATE539060T1/de active
- 2007-04-26 TW TW096114833A patent/TWI399366B/zh active
-
2008
- 2008-08-05 US US12/186,072 patent/US8506929B2/en active Active
- 2008-08-20 IL IL193567A patent/IL193567A/en active IP Right Grant
- 2008-09-16 ZA ZA2008/07955A patent/ZA200807955B/en unknown
- 2008-09-29 KR KR1020087023884A patent/KR101376807B1/ko active IP Right Grant
- 2008-09-30 CR CR10329A patent/CR10329A/es unknown
- 2008-09-30 GT GT200800201A patent/GT200800201A/es unknown
- 2008-09-30 EC EC2008008783A patent/ECSP088783A/es unknown
- 2008-10-29 NO NO20084590A patent/NO342090B1/no active Protection Beyond IP Right Term
-
2012
- 2012-02-10 HR HR20120135T patent/HRP20120135T1/hr unknown
- 2012-03-07 CY CY20121100225T patent/CY1113048T1/el unknown
-
2013
- 2013-01-07 US US13/735,609 patent/US8840866B2/en active Active
- 2013-06-26 LU LU92232C patent/LU92232I2/fr unknown
- 2013-06-26 FR FR13C0034C patent/FR13C0034I2/fr active Active
- 2013-06-27 HU HUS1300028C patent/HUS1300028I1/hu unknown
- 2013-06-27 CY CY2013024C patent/CY2013024I1/el unknown
-
2017
- 2017-06-06 HR HRP20170857TT patent/HRP20170857T1/hr unknown
- 2017-06-22 CY CY20171100664T patent/CY1119048T1/el unknown
-
2018
- 2018-09-11 NO NO2018030C patent/NO2018030I1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUS1300028I1 (hu) | Sztiril-piridin-származékok és alkalmazásuk amyloid-plakkok megkötésére és leképezésére | |
MX2007007380A (es) | Derivados de estilbeno y su uso para estudios de union y por imagenes de placas amiloides. | |
WO2008073350A3 (en) | Acetylene derivatives and their use for binding and imaging amyloid plaques | |
WO2006078384A3 (en) | Stilbene derivatives and their use | |
HUE059861T2 (hu) | N-Szubsztituált 2,5-dioxo-azolin vegyületek a rák kezelésében való felhasználásra | |
HK1110313A1 (en) | Stilbene derivatives and their use for binding and imaging amyloid plaques | |
WO2007033080A3 (en) | Alzheimer's disease imaging agents | |
EP1907846A4 (en) | METHOD AND COMPOSITION FOR DIAGNOSIS OF NEUROLOGICAL DISORDERS IN BODY FLUIDS | |
WO2008003943A3 (en) | Inhibition of alpha-synuclein aggregation | |
ZA201005116B (en) | 6.7-dialkoxy ouinazoline derivatives useful for treatment of cancer related disorders | |
IL200764A (en) | Preparations containing 3epha antibodies for use in the treatment of cancerous tumors | |
PL2401263T3 (pl) | Podstawione pochodne azotu, zawierająca pochodne kompozycja farmaceutyczna, i sposób leczenia choroby Parkinsona przy ich użyciu | |
HK1121378A1 (en) | Compositions and methods for the treatment of addiction and other neuropsychiatric disorders | |
IL196561A0 (en) | Compositions and methods for treating diabetes and neuropsychological dysfunction | |
EP1846432A4 (en) | METHOD FOR MANUFACTURING TARGETED THERAPEUTIC AGENTS | |
WO2006136454A3 (de) | Verwendung von inhibitorn der n-methyltransferasen in der therapie des parkinson-symdroms | |
EP2214488A4 (en) | COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE AND RELATED DISORDERS | |
WO2008050133A3 (en) | Inhibition of beta-amyloid aggregation | |
UA91996C2 (ru) | Производные стильбена и их применение для связывания и визуализации амилоидных бляшек | |
EP1942909A4 (en) | METHODS OF TREATING RESPIRATORY DISORDERS | |
WO2010135493A3 (en) | Alzheimer's disease imaging agents | |
EP1937242A4 (en) | METHOD AND COMPOSITIONS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISEASES AND ADDITIVES | |
UA99579C2 (ru) | АНТИТЕЛО, КОТОРОЕ СВЯЗЫВАЕТСЯ С Tau, ФОСФОРИЛИРОВАННЫМ ПО СЕРИНУ 422 (pS422), ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ ТАУПАТИИ | |
GB0620693D0 (en) | Composition and methods for the treatment of degenerative disease | |
EP1970075A4 (en) | THERAPEUTIC AGENT FOR NEUROBLASTOM TARGETING ARID3b |